Year |
Citation |
Score |
2023 |
Barbosa K, Deshpande A, Perales ME, Xiang P, Murad R, Pramod AB, Minkina A, Robertson NA, Schischlik F, Lei X, Sun Y, Brown A, Amend D, Jeremias I, Doench JG, ... ... Mali P, et al. TRANSCRIPTIONAL CONTROL OF LEUKEMOGENESIS BY THE CHROMATIN READER SGF29. Blood. PMID 38048593 DOI: 10.1182/blood.2023021234 |
0.507 |
|
2023 |
Ford K, Munson BP, Fong SH, Panwala R, Chu WK, Rainaldi J, Plongthongkum N, Arunachalam V, Kostrowicki J, Meluzzi D, Kreisberg JF, Jensen-Pergakes K, VanArsdale T, Paul T, Tamayo P, ... ... Mali P, et al. Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation. Scientific Reports. 13: 7678. PMID 37169829 DOI: 10.1038/s41598-023-33329-2 |
0.759 |
|
2023 |
Booth BJ, Nourreddine S, Katrekar D, Savva Y, Bose D, Long TJ, Huss DJ, Mali P. RNA Editing: Expanding the Potential of RNA Therapeutics. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36620962 DOI: 10.1016/j.ymthe.2023.01.005 |
0.778 |
|
2022 |
Tabet D, Parikh V, Mali P, Roth FP, Claussnitzer M. Scalable Functional Assays for the Interpretation of Human Genetic Variation. Annual Review of Genetics. PMID 36055970 DOI: 10.1146/annurev-genet-072920-032107 |
0.5 |
|
2022 |
Xiang Y, Katrekar D, Mali P. Methods For Recruiting Endogenous And Exogenous ADAR Enzymes For Site-Specific RNA Editing. Methods (San Diego, Calif.). PMID 35779766 DOI: 10.1016/j.ymeth.2022.06.011 |
0.317 |
|
2021 |
Leeper K, Kalhor K, Vernet A, Graveline A, Church GM, Mali P, Kalhor R. Lineage barcoding in mice with homing CRISPR. Nature Protocols. PMID 33692551 DOI: 10.1038/s41596-020-00485-y |
0.775 |
|
2020 |
McDonald D, Wu Y, Dailamy A, Tat J, Parekh U, Zhao D, Hu M, Tipps A, Zhang K, Mali P. Defining the Teratoma as a Model for Multi-lineage Human Development. Cell. PMID 33152263 DOI: 10.1016/j.cell.2020.10.018 |
0.407 |
|
2020 |
Kumar A, Mali P. Mapping regulators of cell fate determination: Approaches and challenges. Apl Bioengineering. 4: 031501. PMID 32637855 DOI: 10.1063/5.0004611 |
0.338 |
|
2020 |
Rocca CJ, Rainaldi JN, Sharma J, Shi Y, Haquang JH, Luebeck J, Mali P, Cherqui S. CRISPR-Cas9 Gene Editing of Hematopoietic Stem Cells from Patients with Friedreich's Ataxia. Molecular Therapy. Methods & Clinical Development. 17: 1026-1036. PMID 32462051 DOI: 10.1016/J.Omtm.2020.04.018 |
0.781 |
|
2019 |
Moreno AM, Palmer N, Alemán F, Chen G, Pla A, Jiang N, Leong Chew W, Law M, Mali P. Immune-orthogonal orthologues of AAV capsids and of Cas9 circumvent the immune response to the administration of gene therapy. Nature Biomedical Engineering. PMID 31332341 DOI: 10.1038/S41551-019-0431-2 |
0.328 |
|
2019 |
Mali P. Humanizing Transcriptome Engineering. Cell. 178: 8-9. PMID 31251918 DOI: 10.1016/J.Cell.2019.06.009 |
0.412 |
|
2019 |
Chen G, Katrekar D, Mali P. RNA-Guided Adenosine Deaminases: Advances and Challenges for Therapeutic RNA Editing. Biochemistry. PMID 30943016 DOI: 10.1021/Acs.Biochem.9B00046 |
0.418 |
|
2019 |
Katrekar D, Chen G, Meluzzi D, Ganesh A, Worlikar A, Shih YR, Varghese S, Mali P. In vivo RNA editing of point mutations via RNA-guided adenosine deaminases. Nature Methods. PMID 30737497 DOI: 10.1038/S41592-019-0323-0 |
0.405 |
|
2019 |
Deshpande A, Chen BR, Zhao L, Saddoris K, Kerr M, Zhu N, Mali P, Deshpande AJ. Investigation of Genetic Dependencies Using CRISPR-Cas9-based Competition Assays. Journal of Visualized Experiments : Jove. PMID 30663717 DOI: 10.3791/58710 |
0.428 |
|
2018 |
Parekh U, Wu Y, Zhao D, Worlikar A, Shah N, Zhang K, Mali P. Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout. Cell Systems. PMID 30448000 DOI: 10.1016/J.Cels.2018.10.008 |
0.448 |
|
2018 |
Hu M, Dailamy A, Lei XY, Parekh U, McDonald D, Kumar A, Mali P. Facile Engineering of Long-Term Culturable Ex Vivo Vascularized Tissues Using Biologically Derived Matrices. Advanced Healthcare Materials. e1800845. PMID 30369101 DOI: 10.1002/Adhm.201800845 |
0.334 |
|
2018 |
Kalhor R, Kalhor K, Mejia L, Leeper K, Graveline A, Mali P, Church GM. Developmental barcoding of whole mouse via homing CRISPR. Science (New York, N.Y.). PMID 30093604 DOI: 10.1126/Science.Aat9804 |
0.771 |
|
2018 |
Ford K, McDonald D, Mali P. Functional Genomics via CRISPR-Cas. Journal of Molecular Biology. PMID 29959923 DOI: 10.1016/J.Jmb.2018.06.034 |
0.367 |
|
2018 |
Moreno AM, Fu X, Zhu J, Katrekar D, Shih YV, Marlett J, Cabotaje J, Tat J, Naughton J, Lisowski L, Varghese S, Zhang K, Mali P. In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29754775 DOI: 10.1016/J.Ymthe.2018.04.017 |
0.461 |
|
2018 |
Katrekar D, Moreno AM, Chen G, Worlikar A, Mali P. Oligonucleotide conjugated multi-functional adeno-associated viruses. Scientific Reports. 8: 3589. PMID 29483550 DOI: 10.1038/S41598-018-21742-X |
0.364 |
|
2018 |
Zhao D, Badur MG, Luebeck J, Magaña JH, Birmingham A, Sasik R, Ahn CS, Ideker T, Metallo CM, Mali P. Combinatorial CRISPR-Cas9 Metabolic Screens Reveal Critical Redox Control Points Dependent on the KEAP1-NRF2 Regulatory Axis. Molecular Cell. 69: 699-708.e7. PMID 29452643 DOI: 10.1016/J.Molcel.2018.01.017 |
0.309 |
|
2018 |
Shen JP, Zhao D, Munson B, Birmingham A, Sasik R, Bojorquez-Gomez A, Licon K, Klepper K, Beckett A, Sanchez KS, Mali P, Ideker T. Abstract 3299: High-throughput combinatorial CRISPR-Cas9 gene knockout reveals most genetic interactions are context dependent Cancer Research. 78: 3299-3299. DOI: 10.1158/1538-7445.Am2018-3299 |
0.369 |
|
2017 |
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Corrigendum: Engineering and optimising deaminase fusions for genome editing. Nature Communications. 8: 16169. PMID 28991237 DOI: 10.1038/Ncomms16169 |
0.736 |
|
2017 |
Du D, Roguev A, Gordon DE, Chen M, Chen SH, Shales M, Shen JP, Ideker T, Mali P, Qi LS, Krogan NJ. Genetic interaction mapping in mammalian cells using CRISPR interference. Nature Methods. PMID 28481362 DOI: 10.1038/Nmeth.4286 |
0.404 |
|
2017 |
Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, ... ... Mali P, et al. Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions. Nature Methods. PMID 28319113 DOI: 10.1038/Nmeth.4225 |
0.6 |
|
2017 |
Moreno AM, Mali P. Therapeutic genome engineering via CRISPR-Cas systems. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 28198142 DOI: 10.1002/Wsbm.1380 |
0.412 |
|
2017 |
Kalhor R, Mali P, Church GM. Rapidly evolving homing CRISPR barcodes. Nature Methods. 14: 195-200. PMID 27918539 DOI: 10.1038/Nmeth.4108 |
0.805 |
|
2017 |
Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Kreisberg J, Ideker T, Mali P. Abstract PR08: Combinatorial CRISPR-Cas9 reveals many cancer synthetic lethal interactions are private to cell type Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr08 |
0.405 |
|
2017 |
Shen JP, Zhao D, Sasik R, Luebeck J, Bojorquez-Gomez A, Licon K, Ideker T, Mali P. Abstract 3039: Combinatorial CRISPR-Cas9 gene knockout to enable genetic interaction mapping in human cells Cancer Research. 77: 3039-3039. DOI: 10.1158/1538-7445.Am2017-3039 |
0.383 |
|
2017 |
Parekh U, Yusupova M, Mali P. Genome engineering in human pluripotent stem cells Current Opinion in Chemical Engineering. 15: 56-67. DOI: 10.1016/J.Coche.2016.12.002 |
0.456 |
|
2017 |
Katrekar D, Hu M, Mali P. Advances in CRISPR-Cas based genome engineering Current Opinion in Biomedical Engineering. 1: 78-86. DOI: 10.1016/J.Cobme.2017.04.001 |
0.391 |
|
2016 |
Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Engineering and optimising deaminase fusions for genome editing. Nature Communications. 7: 13330. PMID 27804970 DOI: 10.1038/Ncomms13330 |
0.774 |
|
2016 |
Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM. A multifunctional AAV-CRISPR-Cas9 and its host response. Nature Methods. 13: 868-74. PMID 27595405 DOI: 10.1038/Nmeth.3993 |
0.55 |
|
2015 |
Chari R, Mali P, Moosburner M, Church GM. Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach. Nature Methods. 12: 823-6. PMID 26167643 DOI: 10.1038/Nmeth.3473 |
0.573 |
|
2015 |
Byrne SM, Ortiz L, Mali P, Aach J, Church GM. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Research. 43: e21. PMID 25414332 DOI: 10.1093/Nar/Gku1246 |
0.589 |
|
2015 |
Mali P. DNA Editing: A Primer Blood. 126. DOI: 10.1182/Blood.V126.23.Sci-16.Sci-16 |
0.437 |
|
2014 |
Byrne SM, Mali P, Church GM. Genome editing in human stem cells. Methods in Enzymology. 546: 119-38. PMID 25398338 DOI: 10.1016/B978-0-12-801185-0.00006-4 |
0.633 |
|
2014 |
Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Yang JL, Ferrante TC, Terry R, Jeanty SS, Li C, Amamoto R, Peters DT, Turczyk BM, Marblestone AH, Inverso SA, Bernard A, ... Mali P, et al. Highly multiplexed subcellular RNA sequencing in situ. Science (New York, N.Y.). 343: 1360-3. PMID 24578530 DOI: 10.1126/Science.1250212 |
0.781 |
|
2014 |
Yang L, Mali P, Kim-Kiselak C, Church G. CRISPR-Cas-mediated targeted genome editing in human cells. Methods in Molecular Biology (Clifton, N.J.). 1114: 245-67. PMID 24557908 DOI: 10.1007/978-1-62703-761-7_16 |
0.697 |
|
2013 |
Mali P, Esvelt KM, Church GM. Cas9 as a versatile tool for engineering biology. Nature Methods. 10: 957-63. PMID 24076990 DOI: 10.1038/Nmeth.2649 |
0.745 |
|
2013 |
Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nature Methods. 10: 1116-21. PMID 24076762 DOI: 10.1038/nmeth.2681 |
0.744 |
|
2013 |
Yang L, Guell M, Byrne S, Yang JL, De Los Angeles A, Mali P, Aach J, Kim-Kiselak C, Briggs AW, Rios X, Huang PY, Daley G, Church G. Optimization of scarless human stem cell genome editing. Nucleic Acids Research. 41: 9049-61. PMID 23907390 DOI: 10.1093/Nar/Gkt555 |
0.674 |
|
2013 |
Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church GM. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nature Biotechnology. 31: 833-8. PMID 23907171 DOI: 10.1038/Nbt.2675 |
0.797 |
|
2013 |
Kusuma S, Shen YI, Hanjaya-Putra D, Mali P, Cheng L, Gerecht S. Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix. Proceedings of the National Academy of Sciences of the United States of America. 110: 12601-6. PMID 23858432 DOI: 10.1073/pnas.1306562110 |
0.5 |
|
2013 |
Mali P, Aach J, Lee JH, Levner D, Nip L, Church GM. Barcoding cells using cell-surface programmable DNA-binding domains. Nature Methods. 10: 403-6. PMID 23503053 DOI: 10.1038/Nmeth.2407 |
0.591 |
|
2013 |
DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM. Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Research. 41: 4336-43. PMID 23460208 DOI: 10.1093/Nar/Gkt135 |
0.799 |
|
2013 |
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. RNA-guided human genome engineering via Cas9. Science (New York, N.Y.). 339: 823-6. PMID 23287722 DOI: 10.1126/Science.1232033 |
0.806 |
|
2012 |
Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Research. 40: e117. PMID 22740649 DOI: 10.1093/Nar/Gks624 |
0.636 |
|
2012 |
Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JS, Gerecht S, Wirtz D. The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. Plos One. 7: e36689. PMID 22574215 DOI: 10.1371/Journal.Pone.0036689 |
0.488 |
|
2012 |
Zou C, Chou BK, Dowey SN, Tsang K, Huang X, Liu CF, Smith C, Yen J, Mali P, Zhang YA, Cheng L, Ye Z. Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Stem Cells and Development. 21: 2298-311. PMID 22225458 DOI: 10.1089/Scd.2011.0688 |
0.757 |
|
2012 |
Mali P, Cheng L. Concise review: Human cell engineering: cellular reprogramming and genome editing. Stem Cells (Dayton, Ohio). 30: 75-81. PMID 21905170 DOI: 10.1002/Stem.735 |
0.642 |
|
2012 |
Shah SN, Kerr C, Cope L, Mali P, Zambidis E, Lui C, Hillion J, Belton A, Huso D, Resar L. Abstract 429: The high mobility group A1 oncogene enhances cellular reprogramming to a pluripotent stem-like cell Cancer Research. 72: 429-429. DOI: 10.1158/1538-7445.Am2012-429 |
0.464 |
|
2011 |
Zou J, Mali P, Huang X, Dowey SN, Cheng L. Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood. 118: 4599-608. PMID 21881051 DOI: 10.1182/Blood-2011-02-335554 |
0.572 |
|
2011 |
Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Research. 21: 518-29. PMID 21243013 DOI: 10.1038/Cr.2011.12 |
0.746 |
|
2010 |
Mali P, Wirtz D, Searson PC. Interplay of RhoA and motility in the programmed spreading of daughter cells postmitosis. Biophysical Journal. 99: 3526-34. PMID 21112276 DOI: 10.1016/J.Bpj.2010.10.006 |
0.386 |
|
2010 |
Ohm JE, Mali P, Van Neste L, Berman DM, Liang L, Pandiyan K, Briggs KJ, Zhang W, Argani P, Simons B, Yu W, Matsui W, Van Criekinge W, Rassool FV, Zambidis E, et al. Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Research. 70: 7662-73. PMID 20841480 DOI: 10.1158/0008-5472.Can-10-1361 |
0.613 |
|
2010 |
Swistowski A, Peng J, Liu Q, Mali P, Rao MS, Cheng L, Zeng X. Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (Dayton, Ohio). 28: 1893-904. PMID 20715183 DOI: 10.1002/Stem.499 |
0.58 |
|
2010 |
Mali P, Ye Z, Chou BK, Yen J, Cheng L. An improved method for generating and identifying human induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 636: 191-205. PMID 20336524 DOI: 10.1007/978-1-60761-691-7_12 |
0.739 |
|
2010 |
Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, Baylin SB, Yusa K, Bradley A, Meyers DJ, Mukherjee C, Cole PA, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (Dayton, Ohio). 28: 713-20. PMID 20201064 DOI: 10.1002/Stem.402 |
0.757 |
|
2010 |
Huang X, Chou B, Mali P, Ye Z, Dowey SN, Cheng L. Human IPS Cells Generated From Adult Peripheral Blood Cells and Purified CD34+ Cells by a Non-Integrating Plasmid. Blood. 116: 1589-1589. DOI: 10.1182/Blood.V116.21.1589.1589 |
0.743 |
|
2009 |
Ye Z, Zhan H, Mali P, Dowey S, Williams DM, Jang YY, Dang CV, Spivak JL, Moliterno AR, Cheng L. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Blood. 114: 5473-5480. PMID 19797525 DOI: 10.1182/Blood-2009-04-217406 |
0.745 |
|
2009 |
Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 5: 97-110. PMID 19540188 DOI: 10.1016/J.Stem.2009.05.023 |
0.762 |
|
2009 |
Ye Z, Zhan H, Mali P, Dowey S, Williams D, Jang Y, Van Dang C, Spivak JL, Moliterno AR, Cheng L. Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Blood Cells of Healthy Donors and Patients with the JAK2-V617F Somatic Mutation. Blood. 114: 812-812. DOI: 10.1182/Blood.V114.22.812.812 |
0.746 |
|
2008 |
Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L. Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells (Dayton, Ohio). 26: 1998-2005. PMID 18511599 DOI: 10.1634/Stemcells.2008-0346 |
0.748 |
|
2008 |
Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L. Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell. 2: 461-71. PMID 18462696 DOI: 10.1016/J.Stem.2008.03.001 |
0.72 |
|
2008 |
Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L. Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins. Cell Stem Cell. 2: 345-55. PMID 18397754 DOI: 10.1016/J.Stem.2008.02.004 |
0.736 |
|
2007 |
Cai L, Ye Z, Zhou BY, Mali P, Zhou C, Cheng L. Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Research. 17: 62-72. PMID 17211448 DOI: 10.1038/Sj.Cr.7310138 |
0.755 |
|
2006 |
Mali P, Cheng L. Reprogramming somatic cells without fusion or ethical confusion Regenerative Medicine. 1: 837-840. DOI: 10.2217/17460751.1.6.837 |
0.614 |
|
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