Diane Heiser, Ph.D. - Publications

Affiliations: 
2013 Cellular and Molecular Medicine Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Cell Biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Venkatasubramanian M, Schwartz L, Ramachandra N, Bennett J, Subramanian KR, Chen X, Gordon-Mitchell S, Fromowitz A, Pradhan K, Shechter D, Sahu S, Heiser D, Scherle P, Chetal K, Kulkarni A, et al. Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation. Biorxiv : the Preprint Server For Biology. PMID 38370617 DOI: 10.1101/2024.02.04.578798  0.359
2020 Spinner MA, Aleshin A, Santaguida MT, Schaffert SA, Zehnder JL, Patterson AS, Gekas C, Heiser D, Greenberg PL. Ex vivo drug screening defines novel drug sensitivity patterns for informing personalized therapy in myeloid neoplasms. Blood Advances. 4: 2768-2778. PMID 32569379 DOI: 10.1182/Bloodadvances.2020001934  0.325
2019 Spinner MA, Aleshin A, Santaguida MA, Schaffert SA, Abbasi T, Sanders JN, Patterson AS, Heiser D, Zehnder JL, Greenberg PL. A Feasibility Study of Biologically Focused Therapy for Myelodysplastic Syndrome Patients Refractory to Hypomethylating Agents Blood. 134: 4239-4239. DOI: 10.1182/Blood-2019-129473  0.387
2018 Aleshin A, Medeiros BC, Kamble S, Heiser D, Santaguida M, Prashad S, Greenberg PL. Abstract 568: Recurrent drug sensitivity patterns in myelodysplastic syndrome patients are recapitulated by ex vivo drug response profiling Cancer Research. 78: 568-568. DOI: 10.1158/1538-7445.Am2018-568  0.331
2018 Aleshin A, Greenberg PL, Medeiros BC, Heiser D, Santaguida M, Prashad S, Durruthy-Durruthy R, Eastburn DJ. Abstract 3004: Single-cell mutational profiling of clonal evolution in myelodysplastic syndromes (MDS) during therapy and disease progression Cancer Research. 78: 3004-3004. DOI: 10.1158/1538-7445.Am2018-3004  0.463
2017 Cao L, Branstrom A, Baird J, Trotta C, Colacino J, Santaguida MT, Heiser D, Ma M, Kojima K, Peltz S, O'Mara E, Spiegel R, Weetall M. PTC299 Is a Novel DHODH Inhibitor That Modulates VEGFA mRNA Translation and Inhibits Proliferation of a Broad Range of Leukemia Cells Blood. 130: 1371-1371. DOI: 10.1182/Blood.V130.Suppl_1.1371.1371  0.436
2016 Cai S, Kalisky T, Sahoo D, Dalerba P, Feng W, Lin Y, Qian D, Kong A, Yu J, Wang F, Chen EY, Scheeren FA, Kuo AH, Sikandar SS, Hisamori S, ... ... Heiser D, et al. A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland. Cell Stem Cell. PMID 28041896 DOI: 10.1016/J.Stem.2016.11.007  0.411
2016 Jeong Y, Hoang NT, Lovejoy A, Stehr H, Newman AM, Gentles AJ, Kong W, Truong D, Martin S, Chaudhuri A, Heiser D, Zhou L, Say C, Carter JN, Hiniker SM, et al. Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance. Cancer Discovery. PMID 27663899 DOI: 10.1158/2159-8290.Cd-16-0127  0.302
2016 Poitras JL, Heiser D, Li L, Nguyen B, Nagai K, Duffield AS, Gamper C, Small D. Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model. Oncotarget. PMID 27636998 DOI: 10.18632/Oncotarget.11986  0.41
2016 Prashad SL, Drusbosky L, Sibai H, Minden MD, Western SJ, Biondi C, Shah R, Liu D, Nguyen T, Warnock C, Quinzio P, De Silva M, Traer E, Cogle CR, Schimmer AD, ... Heiser D, et al. Ex Vivo High-Throughput Flow Cytometry Screening Identifies Subsets of Responders to Differentiation Agents in Individual AML Patient Samples Blood. 128: 5206-5206. DOI: 10.1182/Blood.V128.22.5206.5206  0.45
2014 Heiser D, Tan YS, Kaplan I, Godsey B, Morisot S, Cheng WC, Small D, Civin CI. Correlated miR-mRNA expression signatures of mouse hematopoietic stem and progenitor cell subsets predict "Stemness" and "Myeloid" interaction networks. Plos One. 9: e94852. PMID 24747944 DOI: 10.1371/Journal.Pone.0094852  0.596
2012 Godsey B, Heiser D, Civin C. Inferring microRNA regulation of mRNA with partially ordered samples of paired expression data and exogenous prediction algorithms. Plos One. 7: e51480. PMID 23284698 DOI: 10.1371/Journal.Pone.0051480  0.533
2012 Chu SH, Heiser D, Li L, Kaplan I, Collector M, Huso D, Sharkis SJ, Civin C, Small D. FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm. Cell Stem Cell. 11: 346-58. PMID 22958930 DOI: 10.1016/J.Stem.2012.05.027  0.625
2011 Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence. Journal of Immunology (Baltimore, Md. : 1950). 186: 2826-34. PMID 21270394 DOI: 10.4049/Jimmunol.1002806  0.609
2011 Chu SH, Heiser D, Li L, Kaplan IM, Huso D, Civin CI, Small D. FLT3-ITD Knock-in Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to a Myeloproliferative Neoplasm Blood. 118: 46-46. DOI: 10.1182/BLOOD.V118.21.46.46  0.649
2010 Scheibner KA, Heiser D, Kaplan IM, Cheng W, Kim M, Bharne SS, Morisot S, Civin CI. MicroRNA Maestros of Hematopoiesis Blood. 116: SCI-32-SCI-32. DOI: 10.1182/Blood.V116.21.Sci-32.Sci-32  0.548
2010 Heiser D, Chu SH, Li L, Kaplan IM, Civin CI, Small D. Sorafenib Treatment Reverses Depletion of Primitive Hematopoietic Stem Cells and Resolves FLT3-ITD Driven Myeloproliferative Disease In a Mouse Model. Blood. 116: 1586-1586. DOI: 10.1182/Blood.V116.21.1586.1586  0.668
2009 Kaplan IM, Morisot S, Heiser D, Cheng W, LaDana C, Civin CI. The Hematopoietic Stem Cell (HSC) Compartment in Tristetraprolin (TTP) Knock-out Mice Is Abnormal Phenotypically but Normal Functionally. Blood. 114: 2541-2541. DOI: 10.1182/Blood.V114.22.2541.2541  0.61
2009 Chu SH, Heiser D, Li L, Kaplan IM, Civin CI, Small D. FLT3 Internal Tandem Duplication (ITD) Mutations Disrupt Homeostasis in Hematopoietic Stem Cells. Blood. 114: 1420-1420. DOI: 10.1182/Blood.V114.22.1420.1420  0.657
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