Maja M. Janas, Ph.D. - Publications

Affiliations: 
2012 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
Genetics, Molecular Biology, Cell Biology

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kumar P, Degaonkar R, Guenther DC, Abramov M, Schepers G, Capobianco M, Jiang Y, Harp J, Kaittanis C, Janas MM, Castoreno A, Zlatev I, Schlegel MK, Herdewijn P, Egli M, et al. Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonuclease. Nucleic Acids Research. PMID 32170309 DOI: 10.1093/Nar/Gkaa125  0.353
2018 Janas MM, Harbison CE, Perry VK, Carito B, Sutherland JE, Vaishnaw AK, Keirstead ND, Warner G. The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies. Toxicologic Pathology. 192623318792537. PMID 30139307 DOI: 10.1177/0192623318792537  0.323
2018 Janas MM, Schlegel MK, Harbison CE, Yilmaz VO, Jiang Y, Parmar R, Zlatev I, Castoreno A, Xu H, Shulga-Morskaya S, Rajeev KG, Manoharan M, Keirstead ND, Maier MA, Jadhav V. Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity. Nature Communications. 9: 723. PMID 29459660 DOI: 10.1038/S41467-018-02989-4  0.353
2014 Bell RE, Khaled M, Netanely D, Schubert S, Golan T, Buxbaum A, Janas MM, Postolsky B, Goldberg MS, Shamir R, Levy C. Transcription factor/microRNA axis blocks melanoma invasion program by miR-211 targeting NUAK1. The Journal of Investigative Dermatology. 134: 441-51. PMID 23934065 DOI: 10.1038/Jid.2013.340  0.553
2013 Horman SR, Janas MM, Litterst C, Wang B, MacRae IJ, Sever MJ, Morrissey DV, Graves P, Luo B, Umesalma S, Qi HH, Miraglia LJ, Novina CD, Orth AP. Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Molecular Cell. 50: 356-67. PMID 23603119 DOI: 10.1016/J.Molcel.2013.03.015  0.705
2012 Janas MM, Wang B, Harris AS, Aguiar M, Shaffer JM, Subrahmanyam YV, Behlke MA, Wucherpfennig KW, Gygi SP, Gagnon E, Novina CD. Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins. Rna (New York, N.Y.). 18: 2041-55. PMID 23019594 DOI: 10.1261/Rna.035675.112  0.714
2012 Janas MM, Wang E, Love T, Harris AS, Stevenson K, Semmelmann K, Shaffer JM, Chen PH, Doench JG, Yerramilli SV, Neuberg DS, Iliopoulos D, Housman DE, Burge CB, Novina CD. Reduced expression of ribosomal proteins relieves microRNA-mediated repression. Molecular Cell. 46: 171-86. PMID 22541556 DOI: 10.1016/J.Molcel.2012.04.008  0.727
2012 Janas MM, Novina CD. Not lost in translation: stepwise regulation of microRNA targets. The Embo Journal. 31: 2446-7. PMID 22522704 DOI: 10.1038/Emboj.2012.119  0.735
2011 Janas MM, Khaled M, Schubert S, Bernstein JG, Golan D, Veguilla RA, Fisher DE, Shomron N, Levy C, Novina CD. Feed-forward microprocessing and splicing activities at a microRNA-containing intron. Plos Genetics. 7: e1002330. PMID 22028668 DOI: 10.1371/Journal.Pgen.1002330  0.709
2010 Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S, Chen PH, Li S, Fletcher AL, Yokoyama S, Scott KL, Garraway LA, Song JS, Granter SR, Turley SJ, et al. Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Molecular Cell. 40: 841-9. PMID 21109473 DOI: 10.1016/J.Molcel.2010.11.020  0.584
2009 Omer AD, Janas MM, Novina CD. The chicken or the egg: microRNA-mediated regulation of mRNA translation or mRNA stability. Molecular Cell. 35: 739-40. PMID 19782024 DOI: 10.1016/J.Molcel.2009.09.003  0.651
2008 Piskounova E, Viswanathan SR, Janas M, LaPierre RJ, Daley GQ, Sliz P, Gregory RI. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. The Journal of Biological Chemistry. 283: 21310-4. PMID 18550544 DOI: 10.1074/Jbc.C800108200  0.592
Show low-probability matches.