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Patrick Paddison - Publications

Affiliations: 
Molecular and Cellular Biology University of Washington, Seattle, Seattle, WA 
Area:
Molecular Biology, Cell Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kuppers DA, Linton J, Ortiz Espinosa S, McKenna KM, Rongvaux A, Paddison PJ. Gene knock-outs in human CD34+ hematopoietic stem and progenitor cells and in the human immune system of mice. Plos One. 18: e0287052. PMID 37379309 DOI: 10.1371/journal.pone.0287052  0.352
2023 Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer R, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, ... ... Paddison PJ, et al. WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma. Genes & Development. PMID 36732025 DOI: 10.1101/gad.349803.122  0.364
2020 Hoellerbauer P, Kufeld M, Paddison PJ. Efficient Multi-Allelic Genome Editing of Primary Cell Cultures via CRISPR-Cas9 Ribonucleoprotein Nucleofection. Current Protocols in Stem Cell Biology. 54: e126. PMID 32833346 DOI: 10.1002/cpsc.126  0.311
2019 Mathieu J, Detraux D, Kuppers D, Wang Y, Cavanaugh C, Sidhu S, Levy S, Robitaille AM, Ferreccio A, Bottorff T, McAlister A, Somasundaram L, Artoni F, Battle S, Hawkins RD, ... ... Paddison PJ, et al. Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency. Nature Communications. 10: 632. PMID 30733432 DOI: 10.1038/S41467-018-08020-0  0.363
2019 Feldman H, Arora S, Hoellerbauer P, Pollard S, Patel A, Plaisier C, Paddison P. STEM-05. NEURAL G0: A NOVEL QUIESCENT-LIKE STATE IN PROLIFERATING HUMAN NEURAL STEM AND GLIOBLASTOMA TUMOR CELLS Neuro-Oncology. 21: vi234-vi234. DOI: 10.1093/Neuonc/Noz175.979  0.381
2019 Hoellerbauer P, Kufeld M, Arora S, Wu H, Feldman H, Paddison P. GENE-10. A SIMPLE AND EFFICIENT METHOD FOR GENERATING MULTI-ALLELIC INSERTION-DELETION MUTATIONS AND PRECISE DELETIONS IN PRIMARY HUMAN CELL CULTURES Neuro-Oncology. 21: vi99-vi99. DOI: 10.1093/Neuonc/Noz175.412  0.446
2019 Szulzewsky F, Hoellerbauer P, Wu H, Cimino PJ, Michor F, Paddison P, Vasioukhin V, Holland E. GENE-04. THE ONCOGENIC FUNCTIONS OF YAP1-GENE FUSIONS CAN BE INHIBITED BY DISRUPTION OF YAP1-TEAD INTERACTION Neuro-Oncology. 21: vi98-vi98. DOI: 10.1093/Neuonc/Noz175.406  0.366
2019 Hoellerbauer P, Kufeld M, Arora S, Girard E, Olson J, Biery M, Chambwe N, Paddison P. COMP-04. MODELING PRECISION ONCOLOGY FOR GLIOBLASTOMA THROUGH INTEGRATION OF DESCRIPTIVE, FUNCTIONAL, AND NETWORK-BASED GENOMICS Neuro-Oncology. 21: vi61-vi62. DOI: 10.1093/Neuonc/Noz175.247  0.443
2019 Feldman H, Mihalas A, Plaisier C, Patel A, Paddison P. CBMT-42. A GENOME-WIDE CRISPR-Cas9 SCREEN FOR GENES REGULATING QUIESCENT-LIKE STATES IN GLIOBLASTOMA Neuro-Oncology. 21: vi42-vi42. DOI: 10.1093/Neuonc/Noz175.164  0.403
2019 Bonifert T, Arora S, Fitzgibbon M, Paddison P. CBMT-38. THERAPEUTIC INHIBITION OF THE SPLICEOSOME IN GLIOBLASTOMA: CHANGES FORM MINOR TO MAJOR Neuro-Oncology. 21: vi41-vi41. DOI: 10.1093/Neuonc/Noz175.160  0.389
2019 Lindsay K, Brenner C, Hockenbery D, Paddison P. CBMT-30. TARGETING NICOTINAMIDE ADENINE DINUCLEOTIDE BIOSYNTHESIS IN CNS TUMORS Neuro-Oncology. 21: vi39-vi39. DOI: 10.1093/Neuonc/Noz175.152  0.41
2019 Pattwell S, Arora S, Cimino PJ, Szulzewsky F, Hoellerbauer P, Hoffstrom B, Boiani N, Ozawa T, Bolouri H, Correnti C, Silber J, Paddison P, Holland E. TMOD-30. CHARACTERIZATION OF AN ALTERNATIVELY SPLICED NTRK2 VARIANT IN GLIOMAS Neuro-Oncology. 21: vi269-vi269. DOI: 10.1093/Neuonc/Noz175.1129  0.379
2018 Lee E, Yong RL, Paddison P, Zhu J. Comparison of glioblastoma (GBM) molecular classification methods. Seminars in Cancer Biology. PMID 30031763 DOI: 10.1016/J.Semcancer.2018.07.006  0.363
2018 Ferreccio A, Mathieu J, Detraux D, Logeshwaran S, Cavanaugh C, Sopher B, Fischer K, Bello T, Hussein AM, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, ... ... Paddison P, et al. Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal. Cell Cycle (Georgetown, Tex.). 0. PMID 29466914 DOI: 10.1080/15384101.2018.1442621  0.4
2017 Lee E, Pain M, Wang H, Herman JA, Toledo CM, DeLuca JG, Yong RL, Paddison P, Zhu J. Sensitivity to BUB1B inhibition defines an alternative classification of glioblastoma. Cancer Research. PMID 28855212 DOI: 10.1158/0008-5472.Can-17-0736  0.355
2017 Ding Y, Herman JA, Toledo CM, Lang JM, Corrin P, Girard EJ, Basom R, Delrow JJ, Olson JM, Paddison PJ. ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5. Oncotarget. PMID 28596487 DOI: 10.18632/Oncotarget.18153  0.366
2016 Toledo C, Yu D, Hoellerbauer P, Davis R, Basom R, Girard E, Corrin P, Bolouri H, Davison J, Zhang Q, Nam D, Lee J, Pollard S, Delrow J, Clurman B, ... ... Paddison P, et al. Abstract 4370: Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in patient-derived glioblastoma stem-like cells Cancer Research. 76: 4370-4370. DOI: 10.1158/1538-7445.Am2016-4370  0.466
2015 Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, ... ... Paddison PJ, et al. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Reports. PMID 26673326 DOI: 10.1016/J.Celrep.2015.11.021  0.393
2015 Nayak RC, Trump LR, Aronow BJ, Myers K, Mehta P, Kalfa T, Wellendorf AM, Valencia CA, Paddison PJ, Horwitz MS, Grimes HL, Lutzko C, Cancelas JA. Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells Journal of Clinical Investigation. 125: 3103-3116. DOI: 10.1172/JCI80924  0.302
2015 Toledo C, Ding Y, Hoellerbauer P, Davis R, Basom R, Girard E, Corrin P, Delrow J, Clurman B, Olson J, Paddison P. ATPS-60COMPREHENSIVE IDENTIFICATION OF GLIOBLASTOMA MULTIFORME THERAPEUTIC TARGETS AND GROWTH SUPPRESSOR GENES USING GENE EDITING Neuro-Oncology. 17: v31.3-v31. DOI: 10.1093/Neuonc/Nov204.60  0.423
2014 Schones DE, Chen X, Trac C, Setten R, Paddison PJ. G9a/GLP-dependent H3K9me2 patterning alters chromatin structure at CpG islands in hematopoietic progenitors. Epigenetics & Chromatin. 7: 23. PMID 25237399 DOI: 10.1186/1756-8935-7-23  0.673
2013 Danovi D, Folarin A, Gogolok S, Ender C, Elbatsh AM, Engström PG, Stricker SH, Gagrica S, Georgian A, Yu D, U KP, Harvey KJ, Ferretti P, Paddison PJ, Preston JE, et al. A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1. Plos One. 8: e77053. PMID 24204733 DOI: 10.1371/Journal.Pone.0077053  0.343
2013 Hubert CG, Bradley RK, Ding Y, Toledo CM, Herman J, Skutt-Kakaria K, Girard EJ, Davison J, Berndt J, Corrin P, Hardcastle J, Basom R, Delrow JJ, Webb T, Pollard SM, ... ... Paddison PJ, et al. Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A. Genes & Development. 27: 1032-45. PMID 23651857 DOI: 10.1101/Gad.212548.112  0.334
2013 Betschinger J, Nichols J, Dietmann S, Corrin PD, Paddison PJ, Smith A. Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 153: 335-47. PMID 23582324 DOI: 10.1016/j.cell.2013.03.012  0.355
2013 Guo H, Isserlin R, Chen X, Wang W, Phanse S, Zandstra PW, Paddison PJ, Emili A. Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping. Proteomics. 13: 1325-33. PMID 23401153 DOI: 10.1002/Pmic.201200369  0.64
2013 Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, ... ... Paddison PJ, et al. Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells. Cancer Discovery. 3: 198-211. PMID 23154965 DOI: 10.1158/2159-8290.Cd-12-0353  0.306
2013 Ding Y, Hubert C, Herman J, DeLuca J, Olson J, Paddison P. Abstract A05: Functional genetic approach identifies cancer-specific requirement for BUB1B/BubR1 in human brain tumor isolates and genetically transformed cells Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A05  0.39
2012 Chen X, Skutt-Kakaria K, Davison J, Ou YL, Choi E, Malik P, Loeb K, Wood B, Georges G, Torok-Storb B, Paddison PJ. G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment. Genes & Development. 26: 2499-511. PMID 23105005 DOI: 10.1101/Gad.200329.112  0.689
2012 Wang Y, Hayes VM, Lu L, Chen X, Fuentes R, Wen QJ, Chou ST, Crispino J, Paddison P, French DL, Torok-Storb B, Poncz M. Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs) Blood. 120: 3450-3450. DOI: 10.1182/Blood.V120.21.3450.3450  0.652
2009 Schaniel C, Ang YS, Ratnakumar K, Cormier C, James T, Bernstein E, Lemischka IR, Paddison PJ. Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 2979-91. PMID 19785031 DOI: 10.1002/Stem.223  0.345
2003 Hemann MT, Fridman JS, Zilfou JT, Hernando E, Paddison PJ, Cordon-Cardo C, Hannon GJ, Lowe SW. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nature Genetics. 33: 396-400. PMID 12567186 DOI: 10.1038/Ng1091  0.319
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