| Year |
Citation |
Score |
| 2024 |
Nguyen V, Schrank TP, Major MB, Weissman BE. ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas. Plos One. 19: e0297741. PMID 38358974 DOI: 10.1371/journal.pone.0297741 |
0.387 |
|
| 2023 |
Guan L, Nambiar DK, Cao H, Viswanathan V, Kwok S, Hui AB, Hou Y, Hildebrand R, von Eyben R, Holmes BJ, Zhao J, Kong CS, Wamsley N, Zhang W, Major MB, et al. NFE2L2 mutations enhance radioresistance in head and neck cancer by modulating intratumoral myeloid cells. Cancer Research. PMID 36652552 DOI: 10.1158/0008-5472.CAN-22-1903 |
0.302 |
|
| 2020 |
Song S, Nguyen V, Schrank T, Mulvaney K, Walter V, Wei D, Orvis T, Desai N, Zhang J, Hayes DN, Zheng Y, Major MB, Weissman BE. Loss of SWI/SNF chromatin remodeling alters NRF2 signaling in non-small cell lung carcinoma. Molecular Cancer Research : McR. PMID 32855269 DOI: 10.1158/1541-7786.Mcr-20-0082 |
0.467 |
|
| 2020 |
Skrajna A, Goldfarb D, Kedziora KM, Cousins EM, Grant GD, Spangler CJ, Barbour EH, Yan X, Hathaway NA, Brown NG, Cook JG, Major MB, McGinty RK. Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding. Nucleic Acids Research. PMID 32658293 DOI: 10.1093/Nar/Gkaa544 |
0.38 |
|
| 2020 |
Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Muvlaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, ... Major MB, et al. A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue. The Journal of Pathology. PMID 32619021 DOI: 10.1002/Path.5504 |
0.489 |
|
| 2019 |
Panea RI, Love CL, Shingleton JR, Reddy A, Bailey JA, Moormann AM, Otieno JA, Ong'echa JM, Oduor CI, Schroeder KMS, Masalu N, Chao NJ, Agajanian M, Major MB, Fedoriw Y, et al. The whole genome landscape of Burkitt lymphoma subtypes. Blood. PMID 31558468 DOI: 10.1182/Blood.2019001880 |
0.418 |
|
| 2019 |
Bonin JP, Sapienza PJ, Wilkerson E, Goldfarb D, Wang L, Herring L, Chen X, Major MB, Lee AL. Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase. Biophysical Journal. PMID 31500803 DOI: 10.1016/J.Bpj.2019.08.015 |
0.35 |
|
| 2019 |
Bocanegra JL, Fujita BM, Melton NR, Cowan JM, Schinski EL, Tamir TY, Major MB, Quintero OA. The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes. Cytoskeleton (Hoboken, N.J.). PMID 31479585 DOI: 10.1002/Cm.21560 |
0.33 |
|
| 2019 |
Cloer EW, Goldfarb D, Schrank TP, Weissman BE, Major MB. NRF2 Activation in Cancer: From DNA to Protein. Cancer Research. PMID 30760522 DOI: 10.1158/0008-5472.Can-18-2723 |
0.461 |
|
| 2019 |
Agajanian MJ, Walker MP, Axtman AD, Ruela-de-Sousa RR, Serafin DS, Rabinowitz AD, Graham DM, Ryan MB, Tamir T, Nakamichi Y, Gammons MV, Bennett JM, Couñago RM, Drewry DH, Elkins JM, ... ... Major MB, et al. WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop. Cell Reports. 26: 79-93.e8. PMID 30605688 DOI: 10.1016/J.Celrep.2018.12.023 |
0.353 |
|
| 2018 |
Fu J, Xiong Z, Huang C, Li J, Yang W, Han Y, Paiboonrungruan C, Major MB, Chen K, Kang X, Chen XL. Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus. The Journal of Biological Chemistry. PMID 30409900 DOI: 10.1074/Jbc.Ra118.005963 |
0.387 |
|
| 2018 |
Gao Y, Kardos J, Yang Y, Tamir TY, Mutter-Rottmayer E, Weissman B, Major MB, Kim WY, Vaziri C. The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells. Scientific Reports. 8: 15304. PMID 30333500 DOI: 10.1038/S41598-018-33601-W |
0.428 |
|
| 2018 |
Cloer EW, Siesser PF, Cousins EM, Goldfarb D, Mowrey DD, Harrison JS, Weir SJ, Dokholyan NV, Major MB. p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2. Molecular and Cellular Biology. 38. PMID 30126895 DOI: 10.1128/Mcb.00644-17 |
0.463 |
|
| 2018 |
Lang JD, Hendricks WPD, Orlando KA, Yin H, Kiefer J, Ramos P, Sharma R, Pirrotte P, Raupach EA, Sereduk C, Tang N, Liang WS, Washington M, Facista SJ, Zismann VL, ... ... Major MB, et al. Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29440177 DOI: 10.1158/1078-0432.Ccr-17-1928 |
0.32 |
|
| 2017 |
Chen PH, Smith TJ, Wu J, Siesser PF, Bisnett BJ, Khan F, Hogue M, Soderblom E, Tang F, Marks JR, Major MB, Swarts BM, Boyce M, Chi JT. Glycosylation of KEAP1 links nutrient sensing to redox stress signaling. The Embo Journal. PMID 28663241 DOI: 10.15252/Embj.201696113 |
0.319 |
|
| 2017 |
Yi JJ, Paranjape SR, Walker MP, Choudhury R, Wolter JM, Fragola G, Emanuele MJ, Major MB, Zylka MJ. The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome. The Journal of Biological Chemistry. PMID 28559284 DOI: 10.1074/Jbc.M117.788448 |
0.441 |
|
| 2017 |
Stratford JK, Yan F, Hill RA, Major MB, Graves LM, Der CJ, Yeh JJ. Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability. Plos One. 12: e0174863. PMID 28380042 DOI: 10.1371/Journal.Pone.0174863 |
0.408 |
|
| 2016 |
Mulvaney KM, Matson JP, Siesser PF, Tamir TY, Goldfarb D, Jacobs TM, Cloer EW, Harrsion JS, Vaziri C, Cook JG, Major MB. Identification and Characterization of MCM3 as a Novel KEAP1 Substrate. The Journal of Biological Chemistry. PMID 27621311 DOI: 10.1074/Jbc.M116.729418 |
0.419 |
|
| 2016 |
Harrison JS, Cornett EM, Goldfarb D, DaRosa PA, Li ZM, Yan F, Dickson BM, Guo AH, Cantu DV, Kaustov L, Brown PJ, Arrowsmith CH, Erie DA, Major MB, Klevit RE, et al. Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. Elife. 5. PMID 27595565 DOI: 10.7554/Elife.17101 |
0.316 |
|
| 2016 |
Gao Y, Mutter-Rottmayer E, Greenwalt AM, Goldfarb D, Yan F, Yang Y, Martinez-Chacin RC, Pearce KH, Tateishi S, Major MB, Vaziri C. A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis. Nature Communications. 7: 12105. PMID 27377895 DOI: 10.1038/Ncomms12105 |
0.332 |
|
| 2016 |
Madan B, Walker MP, Young R, Quick L, Orgel KA, Ryan M, Gupta P, Henrich IC, Ferrer M, Marine S, Roberts BS, Arthur WT, Berndt JD, Oliveira AM, Moon RT, ... ... Major MB, et al. USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162353 DOI: 10.1073/Pnas.1605691113 |
0.4 |
|
| 2016 |
Kim TY, Chang JY, Ku JM, Hong SH, Kim jH, Choi HS, Lee K, Kim M, Woo SM, Major MB, Ko S. Abstract 4543: Substrate trapping proteomics reveals novel mechanism for regulation of mTORC1 signaling by βTrCP-FNIP1/2-FLCN axis Cancer Research. 76: 4543-4543. DOI: 10.1158/1538-7445.Am2016-4543 |
0.427 |
|
| 2015 |
Guntas G, Lewis SM, Mulvaney KM, Cloer EW, Tripathy A, Lane TR, Major MB, Kuhlman B. Engineering a genetically encoded competitive inhibitor of the KEAP1-NRF2 interaction via structure-based design and phage display. Protein Engineering, Design & Selection : Peds. PMID 26489878 DOI: 10.1093/Protein/Gzv055 |
0.376 |
|
| 2015 |
Walker MP, Stopford CM, Cederlund M, Fang F, Jahn C, Rabinowitz AD, Goldfarb D, Graham DM, Yan F, Deal AM, Fedoriw Y, Richards KL, Davis IJ, Weidinger G, Damania B, ... Major MB, et al. FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma. Science Signaling. 8: ra12. PMID 25650440 DOI: 10.1126/Scisignal.2005654 |
0.386 |
|
| 2015 |
Kim TY, Siesser PF, Rossman KL, Goldfarb D, Mackinnon K, Yan F, Yi X, MacCoss MJ, Moon RT, Der CJ, Major MB. Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Molecular and Cellular Biology. 35: 167-81. PMID 25332235 DOI: 10.1128/Mcb.00857-14 |
0.404 |
|
| 2015 |
Walker MP, Major MB, VanHook AM. Science signaling Podcast: 3 February 2015 Science Signaling. 8. DOI: 10.1126/Scisignal.Aaa7112 |
0.314 |
|
| 2014 |
Goldfarb D, Hast BE, Wang W, Major MB. Spotlite: web application and augmented algorithms for predicting co-complexed proteins from affinity purification--mass spectrometry data. Journal of Proteome Research. 13: 5944-55. PMID 25300367 DOI: 10.1021/Pr5008416 |
0.681 |
|
| 2014 |
Chen H, Fu J, Chen H, Hu Y, Soroka DN, Prigge JR, Schmidt EE, Yan F, Major MB, Chen X, Sang S. Ginger compound [6]-shogaol and its cysteine-conjugated metabolite (M2) activate Nrf2 in colon epithelial cells in vitro and in vivo. Chemical Research in Toxicology. 27: 1575-85. PMID 25148906 DOI: 10.1021/Tx500211X |
0.369 |
|
| 2014 |
Orvis T, Hepperla A, Walter V, Song S, Simon J, Parker J, Wilkerson MD, Desai N, Major MB, Hayes DN, Davis IJ, Weissman B. BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization. Cancer Research. 74: 6486-98. PMID 25115300 DOI: 10.1158/0008-5472.Can-14-0061 |
0.398 |
|
| 2014 |
Wei D, Goldfarb D, Song S, Cannon C, Yan F, Sakellariou-Thompson D, Emanuele M, Major MB, Weissman BE, Kuwahara Y. SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development. Molecular Cancer Research : McR. 12: 1574-85. PMID 25009291 DOI: 10.1158/1541-7786.Mcr-14-0005 |
0.367 |
|
| 2014 |
Shah PK, Walker MP, Sims CE, Major MB, Allbritton NL. Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 673-84. PMID 24871928 DOI: 10.1039/C4Ib00050A |
0.343 |
|
| 2014 |
Hast BE, Cloer EW, Goldfarb D, Li H, Siesser PF, Yan F, Walter V, Zheng N, Hayes DN, Major MB. Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination. Cancer Research. 74: 808-17. PMID 24322982 DOI: 10.1158/0008-5472.Can-13-1655 |
0.707 |
|
| 2014 |
Arensman MD, Kovochich AN, Kulikauskas RM, Lay AR, Yang PT, Li X, Donahue T, Major MB, Moon RT, Chien AJ, Dawson DW. WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma. Oncogene. 33: 899-908. PMID 23416978 DOI: 10.1038/Onc.2013.23 |
0.434 |
|
| 2013 |
Conrad W, Major MB, Cleary MA, Ferrer M, Roberts B, Marine S, Chung N, Arthur WT, Moon RT, Berndt JD, Chien AJ. FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells. F1000research. 2: 134. PMID 24358901 DOI: 10.12688/F1000Research.2-134.V2 |
0.408 |
|
| 2013 |
Rasmussen NR, Wright TM, Brooks SA, Hacker KE, Debebe Z, Sendor AB, Walker MP, Major MB, Green J, Wahl GM, Rathmell WK. Receptor tyrosine kinase-like orphan receptor 2 (Ror2) expression creates a poised state of Wnt signaling in renal cancer. The Journal of Biological Chemistry. 288: 26301-10. PMID 23893409 DOI: 10.1074/Jbc.M113.466086 |
0.341 |
|
| 2013 |
Hast BE, Goldfarb D, Mulvaney KM, Hast MA, Siesser PF, Yan F, Hayes DN, Major MB. Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination. Cancer Research. 73: 2199-210. PMID 23382044 DOI: 10.1158/0008-5472.Can-12-4400 |
0.722 |
|
| 2013 |
Song S, Orvis T, Zheng Y, Major MB, Weissman BE. Abstract 1299: KEAP1-NRF2-ARE signaling interacts with the SWI/SNF chromatin remodeling complex in non-small cell lung cancer. Cancer Research. 73: 1299-1299. DOI: 10.1158/1538-7445.Am2013-1299 |
0.465 |
|
| 2012 |
James RG, Davidson KC, Bosch KA, Biechele TL, Robin NC, Taylor RJ, Major MB, Camp ND, Fowler K, Martins TJ, Moon RT. WIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signaling. Plos One. 7: e50457. PMID 23227175 DOI: 10.1371/Journal.Pone.0050457 |
0.366 |
|
| 2012 |
Sorrells S, Carbonneau S, Harrington E, Chen AT, Hast B, Milash B, Pyati U, Major MB, Zhou Y, Zon LI, Stewart RA, Look AT, Jette C. Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53. Plos Genetics. 8: e1002922. PMID 22952453 DOI: 10.1371/Journal.Pgen.1002922 |
0.687 |
|
| 2012 |
Siesser PF, Motolese M, Walker MP, Goldfarb D, Gewain K, Yan F, Kulikauskas RM, Chien AJ, Wordeman L, Major MB. FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. Science Signaling. 5: ra64. PMID 22949735 DOI: 10.1126/Scisignal.2002871 |
0.427 |
|
| 2012 |
Camp ND, James RG, Dawson DW, Yan F, Davison JM, Houck SA, Tang X, Zheng N, Major MB, Moon RT. Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein. The Journal of Biological Chemistry. 287: 6539-50. PMID 22215675 DOI: 10.1074/Jbc.M111.316471 |
0.48 |
|
| 2010 |
Chung N, Marine S, Smith EA, Liehr R, Smith ST, Locco L, Hudak E, Kreamer A, Rush A, Roberts B, Major MB, Moon RT, Arthur W, Cleary M, Strulovici B, et al. A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway. Assay and Drug Development Technologies. 8: 286-94. PMID 20578927 DOI: 10.1089/Adt.2009.0262 |
0.3 |
|
| 2009 |
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Science Signaling. 2: ra25. PMID 19471023 DOI: 10.1126/Scisignal.2000230 |
0.38 |
|
| 2009 |
Berndt JD, Biechele TL, Moon RT, Major MB. Integrative analysis of genome-wide RNA interference screens. Science Signaling. 2: pt4. PMID 19436058 DOI: 10.1126/Scisignal.270Pt4 |
0.357 |
|
| 2009 |
Chien AJ, Moore EC, Lonsdorf AS, Kulikauskas RM, Rothberg BG, Berger AJ, Major MB, Hwang ST, Rimm DL, Moon RT. Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model. Proceedings of the National Academy of Sciences of the United States of America. 106: 1193-8. PMID 19144919 DOI: 10.1073/Pnas.0811902106 |
0.362 |
|
| 2008 |
Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, et al. New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening. Science Signaling. 1: ra12. PMID 19001663 DOI: 10.1126/Scisignal.2000037 |
0.41 |
|
| 2008 |
Major MB, Moon RT, VanHook AM. Science signaling podcast: 11 november 2008 Science Signaling. 1: pc11. DOI: 10.1126/Scisignal.145Pc11 |
0.308 |
|
| 2007 |
De Ferrari GV, Papassotiropoulos A, Biechele T, Wavrant De-Vrieze F, Avila ME, Major MB, Myers A, Sáez K, HenrÃquez JP, Zhao A, Wollmer MA, Nitsch RM, Hock C, Morris CM, Hardy J, et al. Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 9434-9. PMID 17517621 DOI: 10.1073/Pnas.0603523104 |
0.303 |
|
| 2007 |
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science (New York, N.Y.). 316: 1043-6. PMID 17510365 DOI: 10.1126/Science/1141515 |
0.387 |
|
| 2007 |
Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 104: 7444-8. PMID 17460038 DOI: 10.1073/Pnas.0702136104 |
0.385 |
|
| 2007 |
Stoick-Cooper CL, Weidinger G, Riehle KJ, Hubbert C, Major MB, Fausto N, Moon RT. Distinct Wnt signaling pathways have opposing roles in appendage regeneration. Development (Cambridge, England). 134: 479-89. PMID 17185322 DOI: 10.1242/Dev.001123 |
0.342 |
|
| 2004 |
Kloeker S, Major MB, Calderwood DA, Ginsberg MH, Jones DA, Beckerle MC. The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion. The Journal of Biological Chemistry. 279: 6824-33. PMID 14634021 DOI: 10.1074/Jbc.M307978200 |
0.351 |
|
| 2004 |
Major MB, Jones DA. Identification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor beta. The Journal of Biological Chemistry. 279: 5278-87. PMID 14630914 DOI: 10.1074/Jbc.M311517200 |
0.413 |
|
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