| Year |
Citation |
Score |
| 2023 |
Fejza A, Camicia L, Carobolante G, Poletto E, Paulitti A, Schinello G, Di Siena E, Cannizzaro R, Iozzo RV, Baldassarre G, Andreuzzi E, Spessotto P, Mongiat M. Emilin2 fosters vascular stability by promoting pericyte recruitment. Matrix Biology : Journal of the International Society For Matrix Biology. 122: 18-32. PMID 37579864 DOI: 10.1016/j.matbio.2023.08.002 |
0.307 |
|
| 2020 |
Neill T, Buraschi S, Kapoor A, Iozzo RV. Proteoglycan-driven Autophagy: A Nutrient-independent Mechanism to Control Intracellular Catabolism. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 22155420937370. PMID 32623955 DOI: 10.1369/0022155420937370 |
0.414 |
|
| 2020 |
Buraschi S, Neill T, Xu SQ, Palladino C, Belfiore A, Iozzo RV, Morrione A. Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 32417448 DOI: 10.1016/J.Matbio.2020.03.009 |
0.407 |
|
| 2020 |
Neill T, Chen CG, Buraschi S, Iozzo RV. Catabolic degradation of endothelial VEGFA via autophagy. The Journal of Biological Chemistry. PMID 32209654 DOI: 10.1074/Jbc.Ra120.012593 |
0.415 |
|
| 2020 |
Kapoor A, Chen CG, Iozzo RV. Endorepellin evokes an angiostatic stress signaling cascade in endothelial cells. The Journal of Biological Chemistry. PMID 32205445 DOI: 10.1074/Jbc.Ra120.012525 |
0.346 |
|
| 2020 |
Chen CG, Gubbiotti MA, Kapoor A, Han X, Yu Y, Linhardt RJ, Iozzo RV. Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 32084457 DOI: 10.1016/J.Matbio.2020.02.001 |
0.401 |
|
| 2019 |
Mongiat M, Buraschi S, Andreuzzi E, Neill T, Iozzo RV. Extracellular matrix: the gatekeeper of tumor angiogenesis. Biochemical Society Transactions. PMID 31652436 DOI: 10.1042/Bst20190653 |
0.412 |
|
| 2019 |
Han B, Li Q, Wang C, Patel P, Adams SM, Doyran B, Nia HT, Oftadeh R, Zhou S, Li CY, Liu XS, Lu XL, Enomoto-Iwamoto M, Qin L, Mauck RL, ... Iozzo RV, et al. Decorin Regulates the Aggrecan Network Integrity and Biomechanical Functions of Cartilage Extracellular Matrix. Acs Nano. PMID 31550133 DOI: 10.1021/Acsnano.9B04477 |
0.319 |
|
| 2019 |
Pellicani R, Poletto E, Andreuzzi E, Paulitti A, Doliana R, Bizzotto D, Braghetta P, Colladel R, Tarticchio G, Sabatelli P, Bucciotti F, Bressan G, Iozzo RV, Colombatti A, Bonaldo P, et al. Multimerin-2 maintains vascular stability and permeability. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 31422156 DOI: 10.1016/J.Matbio.2019.08.002 |
0.401 |
|
| 2019 |
Gubbiotti MA, Buraschi S, Kapoor A, Iozzo RV. Proteoglycan signaling in tumor angiogenesis and endothelial cell autophagy. Seminars in Cancer Biology. PMID 31078640 DOI: 10.1016/J.Semcancer.2019.05.003 |
0.33 |
|
| 2019 |
Passi A, Vigetti D, Buraschi S, Iozzo RV. Dissecting the role of hyaluronan synthases in the tumor microenvironment. The Febs Journal. PMID 30974514 DOI: 10.1111/Febs.14847 |
0.405 |
|
| 2019 |
Chen C, Kapoor A, Iozzo RV. Methods for Monitoring Matrix-Induced Autophagy. Methods in Molecular Biology (Clifton, N.J.). 1952: 157-191. PMID 30825174 DOI: 10.1007/978-1-4939-9133-4_14 |
0.345 |
|
| 2018 |
Lin R, Cai J, Kenyon L, Iozzo R, Rosenwasser R, Iacovitti L. Systemic factors trigger vasculature cells to drive Notch signaling and neurogenesis in neural stem cells in the adult brain. Stem Cells (Dayton, Ohio). PMID 30431198 DOI: 10.1002/Stem.2947 |
0.335 |
|
| 2018 |
Karamanos NK, Piperigkou Z, Theocharis AD, Watanabe H, Franchi M, Baud S, Brézillon S, Götte M, Passi A, Vigetti D, Ricard-Blum S, Sanderson RD, Neill T, Iozzo RV. Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics. Chemical Reviews. PMID 30204432 DOI: 10.1021/Acs.Chemrev.8B00354 |
0.335 |
|
| 2018 |
Karamanos NK, Theocharis AD, Neill T, Iozzo RV. Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 30130584 DOI: 10.1016/J.Matbio.2018.08.007 |
0.328 |
|
| 2018 |
Xu SQ, Buraschi S, Tanimoto R, Stefanello M, Belfiore A, Iozzo RV, Morrione A. Analysis of Progranulin-Mediated Akt and MAPK Activation. Methods in Molecular Biology (Clifton, N.J.). 1806: 121-130. PMID 29956273 DOI: 10.1007/978-1-4939-8559-3_9 |
0.336 |
|
| 2018 |
Neill T, Andreuzzi E, Wang ZX, Peiper SC, Mongiat M, Iozzo RV. Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature. The Journal of Biological Chemistry. PMID 29921586 DOI: 10.1074/Jbc.Ra118.002934 |
0.401 |
|
| 2018 |
Bouris P, Manou D, Sopaki-Valalaki A, Kolokotroni A, Moustakas A, Kapoor A, Iozzo RV, Karamanos NK, Theocharis AD. Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29842969 DOI: 10.1016/J.Matbio.2018.05.011 |
0.346 |
|
| 2018 |
Karalis TT, Heldin P, Vynios DH, Neill T, Buraschi S, Iozzo RV, Karamanos NK, Skandalis SS. Tumor-suppressive functions of 4-MU on breast cancer cells of different ER status: Regulation of hyaluronan/HAS2/CD44 and specific matrix effectors. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29673760 DOI: 10.1016/J.Matbio.2018.04.007 |
0.355 |
|
| 2018 |
Iozzo RV, Gubbiotti MA. Extracellular matrix: The driving force of mammalian diseases. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29625183 DOI: 10.1016/J.Matbio.2018.03.023 |
0.324 |
|
| 2018 |
Montano M, Dinnon KH, Jacobs L, Xiang W, Iozzo RV, Bushman W. Dual Regulation of Decorin by Androgen and Hedgehog Signaling During Prostate Morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 29368411 DOI: 10.1002/Dvdy.24619 |
0.308 |
|
| 2017 |
Buraschi S, Neill T, Iozzo RV. Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29080840 DOI: 10.1016/J.Matbio.2017.10.005 |
0.406 |
|
| 2017 |
Robinson KA, Sun M, Barnum CE, Weiss SN, Huegel J, Shetye SS, Lin L, Saez D, Adams SM, Iozzo RV, Soslowsky LJ, Birk DE. Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28882761 DOI: 10.1016/J.Matbio.2017.08.004 |
0.321 |
|
| 2017 |
Neill T, Sharpe C, Owens RT, Iozzo RV. Decorin-Evoked Paternally Expressed Gene 3 (PEG3) is an Upstream Regulator of the Transcription Factor EB (TFEB) in Endothelial Cell Autophagy. The Journal of Biological Chemistry. PMID 28798237 DOI: 10.1074/Jbc.M116.769950 |
0.376 |
|
| 2017 |
Andreuzzi E, Colladel R, Pellicani R, Tarticchio G, Cannizzaro R, Spessotto P, Bussolati B, Brossa A, De Paoli P, Canzonieri V, Iozzo RV, Colombatti A, Mongiat M. The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28435016 DOI: 10.1016/J.Matbio.2017.04.002 |
0.375 |
|
| 2017 |
Tanimoto R, Palladino C, Xu SQ, Buraschi S, Neill T, Gomella LG, Peiper SC, Belfiore A, Iozzo RV, Morrione A. The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28433812 DOI: 10.1016/J.Matbio.2017.04.001 |
0.372 |
|
| 2017 |
Nallasamy S, Yoshida K, Akins M, Myers K, Iozzo R, Mahendroo M. Steroid hormones are key modulators of tissue mechanical function via regulation of collagen and elastic fibers. Endocrinology. PMID 28204185 DOI: 10.1210/En.2016-1930 |
0.307 |
|
| 2017 |
Torres A, Gubbiotti MA, Iozzo RV. Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis. The Journal of Biological Chemistry. PMID 28174297 DOI: 10.1074/Jbc.M116.753632 |
0.393 |
|
| 2016 |
Pozzi A, Yurchenco PD, Iozzo RV. The nature and biology of basement membranes. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28040522 DOI: 10.1016/J.Matbio.2016.12.009 |
0.337 |
|
| 2016 |
Neill T, Buraschi S, Goyal A, Sharpe C, Natkanski E, Schaefer L, Morrione A, Iozzo RV. EphA2 is a functional receptor for the growth factor progranulin. The Journal of Cell Biology. PMID 27903606 DOI: 10.1083/Jcb.201603079 |
0.337 |
|
| 2016 |
Schaefer L, Tredup C, Gubbiotti MA, Iozzo RV. Proteoglycan neofunctions: Regulation of inflammation and autophagy in cancer biology. The Febs Journal. PMID 27860287 DOI: 10.1111/Febs.13963 |
0.331 |
|
| 2016 |
Gubbiotti MA, Vallet SD, Ricard-Blum S, Iozzo RV. Decorin interacting network: A comprehensive analysis of decorin-binding partners and their versatile functions. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27693454 DOI: 10.1016/J.Matbio.2016.09.009 |
0.342 |
|
| 2016 |
Gubbiotti MA, Neill T, Iozzo RV. A current view of perlecan in physiology and pathology: A mosaic of functions. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27613501 DOI: 10.1016/J.Matbio.2016.09.003 |
0.411 |
|
| 2016 |
Frey H, Moreth K, Hsieh LT, Zeng-Brouwers J, Rathkolb B, Fuchs H, Gailus-Durner V, Iozzo RV, de Angelis MH, Schaefer L. A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia. Glycoconjugate Journal. PMID 27600268 DOI: 10.1007/S10719-016-9722-Y |
0.307 |
|
| 2016 |
Tanimoto R, Lu KG, Xu SQ, Buraschi S, Belfiore A, Iozzo RV, Morrione A. Mechanisms of Progranulin Action and Regulation in Genitourinary Cancers. Frontiers in Endocrinology. 7: 100. PMID 27512385 DOI: 10.3389/Fendo.2016.00100 |
0.332 |
|
| 2016 |
Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, Fitzgerald TJ, Altieri DC, et al. αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer Through JNK1-Mediated Activation of Androgen Receptor. Cancer Research. PMID 27450452 DOI: 10.1158/0008-5472.Can-16-0543 |
0.32 |
|
| 2016 |
Goyal A, Gubbiotti MA, Chery DR, Han L, Iozzo RV. Endorepellin-evoked autophagy contributes to angiostasis. The Journal of Biological Chemistry. PMID 27435676 DOI: 10.1074/Jbc.M116.740266 |
0.37 |
|
| 2016 |
Gronau T, Krüger K, Prein C, Aszodi A, Gronau I, Iozzo RV, Mooren FC, Clausen-Schaumann H, Bertrand J, Pap T, Bruckner P, Dreier R. Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin. Annals of the Rheumatic Diseases. PMID 27377816 DOI: 10.1136/Annrheumdis-2016-209319 |
0.326 |
|
| 2016 |
DeRita RM, Zerlanko B, Singh A, Lu H, Iozzo RV, Benovic JL, Languino LR. c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase Are Enriched into Prostate Cancer Cell Exosomes. Journal of Cellular Biochemistry. PMID 27232975 DOI: 10.1002/Jcb.25611 |
0.375 |
|
| 2016 |
Buraschi S, Xu SQ, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Birbe R, Peiper SC, Gomella LG, Belfiore A, Black PC, Iozzo RV, Morrione A. Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin. Oncotarget. PMID 27220888 DOI: 10.18632/Oncotarget.9556 |
0.371 |
|
| 2016 |
Neill T, Schaefer L, Iozzo RV. Decorin as a multivalent therapeutic agent against cancer. Advanced Drug Delivery Reviews. 97: 174-85. PMID 26522384 DOI: 10.1016/J.Addr.2015.10.016 |
0.391 |
|
| 2016 |
Poluzzi C, Iozzo RV, Schaefer L. Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers. Advanced Drug Delivery Reviews. 97: 156-73. PMID 26518982 DOI: 10.1016/J.Addr.2015.10.012 |
0.384 |
|
| 2016 |
Buraschi S, Xu S, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Neill T, Peiper SC, Gomella LG, Belfiore A, Black PC, Iozzo RV, Morrione A. Abstract 698: Progranulin targeting in urothelial cancer cells inhibits motility, tumor growthin vitroandin vivoand sensitizes cells to cisplatin Cancer Research. 76: 698-698. DOI: 10.1158/1538-7445.Am2016-698 |
0.389 |
|
| 2016 |
Xu W, Yang Y, Neill T, Wang H, Wang C, Yun C, Guise T, Brendler CB, Iozzo RV, Wang L, Seth P. 417. Intratumoral Delivery of Oncolytic Adenovirus Expressing Decorin Inhibits Growth and Metastases of 4T1 Breast Tumors in Syngeneic Immune Competent BALB/c Mice Model Molecular Therapy. 24: S165-S166. DOI: 10.1016/S1525-0016(16)33226-9 |
0.323 |
|
| 2016 |
Buraschi S, Xu S, Stefanello M, Moskalev I, Morcavallo A, Genua M, Tanimoto R, Neill T, Peiper SC, Gomella LG, Black PC, Belfiore A, Iozzo RV, Morrione A. MP61-13 PROGRANULIN TARGETING IN UROTHELIAL CANCER CELLS INHIBITS MOTILITY, ANCHORAGE-INDEPENDENT GROWTH, TUMOR FORMATION IN VIVO AND SENSITIZES CELLS TO CISPLATIN Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.887 |
0.374 |
|
| 2015 |
Neill T, Schaefer L, Iozzo RV. Oncosuppressive functions of decorin. Molecular & Cellular Oncology. 2: e975645. PMID 27308453 DOI: 10.4161/23723556.2014.975645 |
0.384 |
|
| 2015 |
Gubbiotti MA, Iozzo RV. Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept. Matrix Biology : Journal of the International Society For Matrix Biology. 48: 6-13. PMID 26462577 DOI: 10.1016/J.Matbio.2015.10.002 |
0.377 |
|
| 2015 |
Gubbiotti MA, Neill T, Frey H, Schaefer L, Iozzo RV. Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 26344480 DOI: 10.1016/J.Matbio.2015.09.001 |
0.388 |
|
| 2015 |
Douglass S, Goyal A, Iozzo RV. The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy. Connective Tissue Research. 56: 381-91. PMID 26181327 DOI: 10.3109/03008207.2015.1045297 |
0.425 |
|
| 2015 |
Neill T, Schaefer L, Iozzo RV. Decoding the Matrix: Instructive Roles of Proteoglycan Receptors. Biochemistry. 54: 4583-98. PMID 26177309 DOI: 10.1021/Acs.Biochem.5B00653 |
0.366 |
|
| 2015 |
Malaguarnera R, Nicolosi ML, Sacco A, Morcavallo A, Vella V, Voci C, Spatuzza M, Xu SQ, Iozzo RV, Vigneri R, Morrione A, Belfiore A. Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses. Oncotarget. PMID 25840417 DOI: 10.18632/Oncotarget.3177 |
0.349 |
|
| 2015 |
Xu SQ, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Birbe R, Belfiore A, Iozzo RV, Morrione A. A novel role for drebrin in regulating progranulin bioactivity in bladder cancer. Oncotarget. 6: 10825-39. PMID 25839164 DOI: 10.18632/Oncotarget.3424 |
0.388 |
|
| 2015 |
Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Sanderson RD, Schaefer L, Iozzo RV, et al. Insights into the key roles of proteoglycans in breast cancer biology and translational medicine. Biochimica Et Biophysica Acta. 1855: 276-300. PMID 25829250 DOI: 10.1016/J.Bbcan.2015.03.006 |
0.343 |
|
| 2015 |
Borges MC, Narayanan V, Iozzo RV, Ludwig MS. Deficiency of decorin induces expression of Foxp3 in CD4(+) CD25(+) T cells in a murine model of allergic asthma. Respirology (Carlton, Vic.). 20: 904-11. PMID 25712878 DOI: 10.1111/Resp.12485 |
0.309 |
|
| 2015 |
Iozzo RV, Schaefer L. Proteoglycan form and function: A comprehensive nomenclature of proteoglycans. Matrix Biology : Journal of the International Society For Matrix Biology. 42: 11-55. PMID 25701227 DOI: 10.1016/J.Matbio.2015.02.003 |
0.334 |
|
| 2015 |
Fedele C, Singh A, Zerlanko BJ, Iozzo RV, Languino LR. The αvβ6 integrin is transferred intercellularly via exosomes. The Journal of Biological Chemistry. 290: 4545-51. PMID 25568317 DOI: 10.1074/Jbc.C114.617662 |
0.367 |
|
| 2015 |
Xu W, Neill T, Yang Y, Hu Z, Cleveland E, Wu Y, Hutten R, Xiao X, Stock SR, Shevrin D, Kaul K, Brendler C, Iozzo RV, Seth P. The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer. Gene Therapy. 22: 31-40. PMID 25503693 DOI: 10.1038/Gt.2014.110 |
0.324 |
|
| 2015 |
Tanimoto R, Morcavallo A, Terracciano M, Xu SQ, Stefanello M, Buraschi S, Lu KG, Bagley DH, Gomella LG, Scotlandi K, Belfiore A, Iozzo RV, Morrione A. Sortilin regulates progranulin action in castration-resistant prostate cancer cells. Endocrinology. 156: 58-70. PMID 25365768 DOI: 10.1210/En.2014-1590 |
0.358 |
|
| 2015 |
Xu S, Buraschi S, Morcavallo A, Genua M, Shirao T, Peiper SC, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Abstract 4945: A novel role for drebrin in regulating progranulin bioactivity in bladder cancer Cancer Research. 75: 4945-4945. DOI: 10.1158/1538-7445.Am2015-4945 |
0.365 |
|
| 2014 |
Morcavallo A, Stefanello M, Iozzo RV, Belfiore A, Morrione A. Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function. Frontiers in Endocrinology. 5: 220. PMID 25566192 DOI: 10.3389/Fendo.2014.00220 |
0.321 |
|
| 2014 |
Theocharis AD, Gialeli C, Bouris P, Giannopoulou E, Skandalis SS, Aletras AJ, Iozzo RV, Karamanos NK. Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer. The Febs Journal. 281: 5023-42. PMID 25333340 DOI: 10.1111/Febs.12927 |
0.369 |
|
| 2014 |
Neill T, Schaefer L, Iozzo RV. Instructive roles of extracellular matrix on autophagy. The American Journal of Pathology. 184: 2146-53. PMID 24976620 DOI: 10.1016/J.Ajpath.2014.05.010 |
0.351 |
|
| 2014 |
Poluzzi C, Casulli J, Goyal A, Mercer TJ, Neill T, Iozzo RV. Endorepellin evokes autophagy in endothelial cells. The Journal of Biological Chemistry. 289: 16114-28. PMID 24737315 DOI: 10.1074/Jbc.M114.556530 |
0.426 |
|
| 2014 |
Goyal A, Neill T, Owens RT, Schaefer L, Iozzo RV. Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 42-50. PMID 24726292 DOI: 10.1016/J.Matbio.2014.04.002 |
0.374 |
|
| 2014 |
Lord MS, Chuang CY, Melrose J, Davies MJ, Iozzo RV, Whitelock JM. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 112-22. PMID 24509440 DOI: 10.1016/J.Matbio.2014.01.016 |
0.392 |
|
| 2014 |
Goyal A, Neill T, Owens RT, Schaefer L, Iozzo RV. Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells. Matrix Biology : Journal of the International Society For Matrix Biology. 34: 46-54. PMID 24472739 DOI: 10.1016/J.Matbio.2013.12.011 |
0.374 |
|
| 2014 |
Nikolovska K, Renke JK, Jungmann O, Grobe K, Iozzo RV, Zamfir AD, Seidler DG. A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 91-102. PMID 24447999 DOI: 10.1016/J.Matbio.2014.01.003 |
0.319 |
|
| 2014 |
Neill T, Torres A, Buraschi S, Owens RT, Hoek JB, Baffa R, Iozzo RV. Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin. The Journal of Biological Chemistry. 289: 4952-68. PMID 24403067 DOI: 10.1074/Jbc.M113.512566 |
0.349 |
|
| 2014 |
Morcavallo A, Buraschi S, Xu SQ, Belfiore A, Schaefer L, Iozzo RV, Morrione A. Decorin differentially modulates the activity of insulin receptor isoform A ligands. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 82-90. PMID 24389353 DOI: 10.1016/J.Matbio.2013.12.010 |
0.304 |
|
| 2014 |
Zeng-Brouwers J, Beckmann J, Nastase MV, Iozzo RV, Schaefer L. De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 132-42. PMID 24361484 DOI: 10.1016/J.Matbio.2013.12.003 |
0.317 |
|
| 2014 |
Horváth Z, Kovalszky I, Fullár A, Kiss K, Schaff Z, Iozzo RV, Baghy K. Decorin deficiency promotes hepatic carcinogenesis. Matrix Biology : Journal of the International Society For Matrix Biology. 35: 194-205. PMID 24361483 DOI: 10.1016/J.Matbio.2013.11.004 |
0.355 |
|
| 2014 |
Fetting JL, Guay JA, Karolak MJ, Iozzo RV, Adams DC, Maridas DE, Brown AC, Oxburgh L. FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney. Development (Cambridge, England). 141: 17-27. PMID 24284212 DOI: 10.1242/Dev.089078 |
0.354 |
|
| 2014 |
Romanello M, Piatkowska E, Antoniali G, Cesaratto L, Vascotto C, Iozzo RV, Delneri D, Brancia FL. Osteoblastic cell secretome: a novel role for progranulin during risedronate treatment. Bone. 58: 81-91. PMID 24120669 DOI: 10.1016/J.Bone.2013.10.003 |
0.358 |
|
| 2014 |
Morcavallo A, Buraschi S, Xu S, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Abstract 4415: Discoidin domain receptor 1 (DDR1) and IGF-I system crosstalk in bladder cancer progression Cancer Research. 74: 4415-4415. DOI: 10.1158/1538-7445.Am2014-4415 |
0.36 |
|
| 2013 |
Neill T, Torres A, Buraschi S, Iozzo RV. Decorin has an appetite for endothelial cell autophagy. Autophagy. 9: 1626-8. PMID 23989617 DOI: 10.4161/Auto.25881 |
0.416 |
|
| 2013 |
Buraschi S, Neill T, Goyal A, Poluzzi C, Smythies J, Owens RT, Schaefer L, Torres A, Iozzo RV. Decorin causes autophagy in endothelial cells via Peg3. Proceedings of the National Academy of Sciences of the United States of America. 110: E2582-91. PMID 23798385 DOI: 10.1073/Pnas.1305732110 |
0.377 |
|
| 2013 |
Chen S, Sun M, Iozzo RV, Kao WW, Birk DE. Intracellularly-retained decorin lacking the C-terminal ear repeat causes ER stress: a cell-based etiological mechanism for congenital stromal corneal dystrophy. The American Journal of Pathology. 183: 247-56. PMID 23685109 DOI: 10.1016/J.Ajpath.2013.04.001 |
0.321 |
|
| 2013 |
Baghy K, Horváth Z, Regős E, Kiss K, Schaff Z, Iozzo RV, Kovalszky I. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. The Febs Journal. 280: 2150-64. PMID 23448253 DOI: 10.1111/Febs.12215 |
0.391 |
|
| 2013 |
Willis CD, Poluzzi C, Mongiat M, Iozzo RV. Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells. The Febs Journal. 280: 2271-84. PMID 23374253 DOI: 10.1111/Febs.12164 |
0.375 |
|
| 2013 |
Morrione A, Neill T, Iozzo RV. Dichotomy of decorin activity on the insulin-like growth factor-I system. The Febs Journal. 280: 2138-49. PMID 23351020 DOI: 10.1111/Febs.12149 |
0.39 |
|
| 2013 |
Neill T, Jones HR, Crane-Smith Z, Owens RT, Schaefer L, Iozzo RV. Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1. The Febs Journal. 280: 2353-68. PMID 23350987 DOI: 10.1111/Febs.12148 |
0.406 |
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| 2013 |
Frey H, Schroeder N, Manon-Jensen T, Iozzo RV, Schaefer L. Biological interplay between proteoglycans and their innate immune receptors in inflammation. The Febs Journal. 280: 2165-79. PMID 23350913 DOI: 10.1111/Febs.12145 |
0.328 |
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| 2013 |
Jung M, Lord MS, Cheng B, Lyons JG, Alkhouri H, Hughes JM, McCarthy SJ, Iozzo RV, Whitelock JM. Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: a role in angiogenesis and wound healing. The Journal of Biological Chemistry. 288: 3289-304. PMID 23235151 DOI: 10.1074/Jbc.M112.387811 |
0.398 |
|
| 2013 |
Bix G, Fu J, Gonzalez EM, Macro L, Barker A, Campbell S, Zutter MM, Santoro SA, Kim JK, Höök M, Reed CC, Iozzo RV. Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin The Journal of Cell Biology. 201: 641-641. DOI: 10.1083/Jcb.20040115004252013C |
0.392 |
|
| 2012 |
Jungmann O, Nikolovska K, Stock C, Schulz JN, Eckes B, Riethmüller C, Owens RT, Iozzo RV, Seidler DG. The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis. Plos One. 7: e50809. PMID 23226541 DOI: 10.1371/Journal.Pone.0050809 |
0.374 |
|
| 2012 |
Goyal A, Poluzzi C, Willis CD, Smythies J, Shellard A, Neill T, Iozzo RV. Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factor of activated T cell 1 (NFAT1) activation. The Journal of Biological Chemistry. 287: 43543-56. PMID 23060442 DOI: 10.1074/Jbc.M112.401786 |
0.37 |
|
| 2012 |
Buraschi S, Neill T, Owens RT, Iniguez LA, Purkins G, Vadigepalli R, Evans B, Schaefer L, Peiper SC, Wang ZX, Iozzo RV. Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. Plos One. 7: e45559. PMID 23029096 DOI: 10.1371/Journal.Pone.0045559 |
0.345 |
|
| 2012 |
Genua M, Xu SQ, Buraschi S, Peiper SC, Gomella LG, Belfiore A, Iozzo RV, Morrione A. Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells. Plos One. 7: e40148. PMID 22859931 DOI: 10.1371/Journal.Pone.0040148 |
0.372 |
|
| 2012 |
Neill T, Schaefer L, Iozzo RV. Decorin: a guardian from the matrix. The American Journal of Pathology. 181: 380-7. PMID 22735579 DOI: 10.1016/J.Ajpath.2012.04.029 |
0.411 |
|
| 2012 |
Moreth K, Iozzo RV, Schaefer L. Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation. Cell Cycle (Georgetown, Tex.). 11: 2084-91. PMID 22580469 DOI: 10.4161/Cc.20316 |
0.328 |
|
| 2012 |
Dourte LM, Pathmanathan L, Jawad AF, Iozzo RV, Mienaltowski MJ, Birk DE, Soslowsky LJ. Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon. Journal of Biomechanical Engineering. 134: 031005. PMID 22482685 DOI: 10.1115/1.4006200 |
0.303 |
|
| 2012 |
Schaefer L, Iozzo RV. Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation. Current Opinion in Genetics & Development. 22: 56-7. PMID 22326829 DOI: 10.1016/J.Gde.2011.12.002 |
0.304 |
|
| 2012 |
Wu Z, Aron AW, Macksoud EE, Iozzo RV, Hai CM, Lechner BE. Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition. Plos One. 7: e29627. PMID 22253749 DOI: 10.1371/Journal.Pone.0029627 |
0.313 |
|
| 2012 |
Neill T, Painter H, Buraschi S, Owens RT, Lisanti MP, Schaefer L, Iozzo RV. Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3. The Journal of Biological Chemistry. 287: 5492-506. PMID 22194599 DOI: 10.1074/Jbc.M111.283499 |
0.394 |
|
| 2012 |
Bi X, Pohl NM, Qian Z, Yang GR, Gou Y, Guzman G, Kajdacsy-Balla A, Iozzo RV, Yang W. Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice. Carcinogenesis. 33: 326-30. PMID 22159220 DOI: 10.1093/Carcin/Bgr293 |
0.361 |
|
| 2012 |
Ichii M, Frank MB, Iozzo RV, Kincade PW. The canonical Wnt pathway shapes niches supportive of hematopoietic stem/progenitor cells. Blood. 119: 1683-92. PMID 22117039 DOI: 10.1182/Blood-2011-07-369199 |
0.334 |
|
| 2012 |
Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Iozzo R, ... ... Iozzo RV, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127 |
0.7 |
|
| 2011 |
Merline R, Moreth K, Beckmann J, Nastase MV, Zeng-Brouwers J, Tralhão JG, Lemarchand P, Pfeilschifter J, Schaefer RM, Iozzo RV, Schaefer L. Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21. Science Signaling. 4: ra75. PMID 22087031 DOI: 10.1126/Scisignal.2001868 |
0.342 |
|
| 2011 |
Seidler DG, Mohamed NA, Bocian C, Stadtmann A, Hermann S, Schäfers K, Schäfers M, Iozzo RV, Zarbock A, Götte M. The role for decorin in delayed-type hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 187: 6108-19. PMID 22043007 DOI: 10.4049/Jimmunol.1100373 |
0.323 |
|
| 2011 |
Iozzo RV. Autophagic tumor stroma: a biofuel for cancer growth. Cell Cycle (Georgetown, Tex.). 10: 3231-2. PMID 21946523 DOI: 10.4161/Cc.10.19.17124 |
0.304 |
|
| 2011 |
Chen S, Sun M, Meng X, Iozzo RV, Kao WW, Birk DE. Pathophysiological mechanisms of autosomal dominant congenital stromal corneal dystrophy: C-terminal-truncated decorin results in abnormal matrix assembly and altered expression of small leucine-rich proteoglycans. The American Journal of Pathology. 179: 2409-19. PMID 21893019 DOI: 10.1016/J.Ajpath.2011.07.026 |
0.341 |
|
| 2011 |
Iozzo RV, Buraschi S, Genua M, Xu SQ, Solomides CC, Peiper SC, Gomella LG, Owens RC, Morrione A. Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling. The Journal of Biological Chemistry. 286: 34712-21. PMID 21840990 DOI: 10.1074/Jbc.M111.262766 |
0.345 |
|
| 2011 |
Castello-Cros R, Whitaker-Menezes D, Molchansky A, Purkins G, Soslowsky LJ, Beason DP, Sotgia F, Iozzo RV, Lisanti MP. Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis. Cell Cycle (Georgetown, Tex.). 10: 2140-50. PMID 21670602 DOI: 10.4161/Cc.10.13.16227 |
0.311 |
|
| 2011 |
Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV. Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism. The Journal of Biological Chemistry. 286: 25947-62. PMID 21596751 DOI: 10.1074/Jbc.M111.243626 |
0.401 |
|
| 2011 |
Fassan M, D'Arca D, Letko J, Vecchione A, Gardiman MP, McCue P, Wildemore B, Rugge M, Shupp-Byrne D, Gomella LG, Morrione A, Iozzo RV, Baffa R. Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells. Plos One. 6: e19771. PMID 21573075 DOI: 10.1371/Journal.Pone.0019771 |
0.353 |
|
| 2011 |
Iozzo RV, Sanderson RD. Proteoglycans in cancer biology, tumour microenvironment and angiogenesis. Journal of Cellular and Molecular Medicine. 15: 1013-31. PMID 21155971 DOI: 10.1111/J.1582-4934.2010.01236.X |
0.406 |
|
| 2011 |
Trimmer C, Sotgia F, Whitaker-Menezes D, Balliet RM, Eaton G, Martinez-Outschoorn UE, Pavlides S, Howell A, Iozzo RV, Pestell RG, Scherer PE, Capozza F, Lisanti MP. Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts. Cancer Biology & Therapy. 11: 383-94. PMID 21150282 DOI: 10.4161/Cbt.11.4.14101 |
0.349 |
|
| 2011 |
Baghy K, Dezso K, László V, Fullár A, Péterfia B, Paku S, Nagy P, Schaff Z, Iozzo RV, Kovalszky I. Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 439-51. PMID 20956977 DOI: 10.1038/Labinvest.2010.172 |
0.302 |
|
| 2011 |
Morrione A, Genua M, Iozzo RV, Gomella LG. Evaluation of the insulin-like growth factor receptor I and Pyk2 kinase in urothelial carcinomas and effect on motility and invasion of urothelial carcinoma-derived cells. Journal of Clinical Oncology. 29: 254-254. DOI: 10.1200/Jco.2011.29.7_Suppl.254 |
0.347 |
|
| 2011 |
Bi X, Yang GR, Gou Y, Pohl N, Guzman G, Kajdacsy-Balla A, Iozzo RV, Yang W. Abstract 1448: Interaction between decorin and E-cadherin/beta-catenin signaling attenuates colorectal cancer growth and metastasis in vitro and in decorin knockout mice Cancer Research. 71: 1448-1448. DOI: 10.1158/1538-7445.Am2011-1448 |
0.367 |
|
| 2011 |
Genua M, Xu S, Gomella LG, Iozzo RV, Morrione A. Abstract 1408: The insulin-like growth factor receptor I and Pyk2 kinase are up-regulated in urothelial carcinomas and promote motility and invasion of urothelial carcinoma-derived cells Cancer Research. 71: 1408-1408. DOI: 10.1158/1538-7445.Am2011-1408 |
0.379 |
|
| 2010 |
Buraschi S, Pal N, Tyler-Rubinstein N, Owens RT, Neill T, Iozzo RV. Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels. The Journal of Biological Chemistry. 285: 42075-85. PMID 20974860 DOI: 10.1074/Jbc.M110.172841 |
0.393 |
|
| 2010 |
Iozzo RV, Schaefer L. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. The Febs Journal. 277: 3864-75. PMID 20840584 DOI: 10.1111/J.1742-4658.2010.07797.X |
0.343 |
|
| 2010 |
Iozzo RV, Karamanos N. Proteoglycans in health and disease: emerging concepts and future directions. The Febs Journal. 277: 3863. PMID 20812984 DOI: 10.1111/J.1742-4658.2010.07796.X |
0.436 |
|
| 2010 |
Chuang CY, Lord MS, Melrose J, Rees MD, Knox SM, Freeman C, Iozzo RV, Whitelock JM. Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan. Biochemistry. 49: 5524-32. PMID 20507176 DOI: 10.1021/Bi1005199 |
0.366 |
|
| 2010 |
Metalli D, Lovat F, Tripodi F, Genua M, Xu SQ, Spinelli M, Alberghina L, Vanoni M, Baffa R, Gomella LG, Iozzo RV, Morrione A. The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin. The American Journal of Pathology. 176: 2997-3006. PMID 20395438 DOI: 10.2353/Ajpath.2010.090904 |
0.372 |
|
| 2010 |
Sanches JC, Jones CJ, Aplin JD, Iozzo RV, Zorn TM, Oliveira SF. Collagen fibril organization in the pregnant endometrium of decorin-deficient mice. Journal of Anatomy. 216: 144-55. PMID 19900179 DOI: 10.1111/J.1469-7580.2009.01170.X |
0.302 |
|
| 2010 |
Rees MD, Whitelock JM, Malle E, Chuang CY, Iozzo RV, Nilasaroya A, Davies MJ. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 63-73. PMID 19788922 DOI: 10.1016/J.Matbio.2009.09.005 |
0.334 |
|
| 2010 |
Ferdous Z, Peterson SB, Tseng H, Anderson DK, Iozzo RV, Grande-Allen KJ. A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts. Journal of Biomedical Materials Research. Part A. 93: 419-28. PMID 19569212 DOI: 10.1002/Jbm.A.32545 |
0.347 |
|
| 2010 |
Metalli D, Lovat F, Tripodi F, Xu S, Alberghina L, Vanoni M, Baffa R, Iozzo RV, Gomella LG, Morrione A. Abstract 5057: The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and MAPK-dependent activation of paxillin Cancer Research. 70: 5057-5057. DOI: 10.1158/1538-7445.Am10-5057 |
0.374 |
|
| 2009 |
Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV. Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood. 114: 4897-906. PMID 19789387 DOI: 10.1182/Blood-2009-02-207134 |
0.37 |
|
| 2009 |
San Antonio JD, Zoeller JJ, Habursky K, Turner K, Pimtong W, Burrows M, Choi S, Basra S, Bennett JS, DeGrado WF, Iozzo RV. A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. The American Journal of Pathology. 175: 1338-47. PMID 19700757 DOI: 10.2353/Ajpath.2009.090234 |
0.74 |
|
| 2009 |
Iozzo RV, Zoeller JJ, Nyström A. Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis. Molecules and Cells. 27: 503-13. PMID 19466598 DOI: 10.1007/S10059-009-0069-0 |
0.741 |
|
| 2009 |
Goldoni S, Humphries A, Nyström A, Sattar S, Owens RT, McQuillan DJ, Ireton K, Iozzo RV. Decorin is a novel antagonistic ligand of the Met receptor. The Journal of Cell Biology. 185: 743-54. PMID 19433454 DOI: 10.1083/Jcb.200901129 |
0.359 |
|
| 2009 |
Zoeller JJ, Whitelock JM, Iozzo RV. Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 284-91. PMID 19422911 DOI: 10.1016/J.Matbio.2009.04.010 |
0.725 |
|
| 2009 |
Haruyama N, Sreenath TL, Suzuki S, Yao X, Wang Z, Wang Y, Honeycutt C, Iozzo RV, Young MF, Kulkarni AB. Genetic evidence for key roles of decorin and biglycan in dentin mineralization. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 129-36. PMID 19379665 DOI: 10.1016/J.Matbio.2009.01.005 |
0.316 |
|
| 2009 |
Lovat F, Bitto A, Xu SQ, Fassan M, Goldoni S, Metalli D, Wubah V, McCue P, Serrero G, Gomella LG, Baffa R, Iozzo RV, Morrione A. Proepithelin is an autocrine growth factor for bladder cancer. Carcinogenesis. 30: 861-8. PMID 19237611 DOI: 10.1093/Carcin/Bgp050 |
0.373 |
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| 2009 |
Zoeller JJ, Pimtong W, Corby H, Goldoni S, Iozzo AE, Owens RT, Ho SY, Iozzo RV. A central role for decorin during vertebrate convergent extension. The Journal of Biological Chemistry. 284: 11728-37. PMID 19211552 DOI: 10.1074/Jbc.M808991200 |
0.72 |
|
| 2009 |
Monami G, Emiliozzi V, Bitto A, Lovat F, Xu SQ, Goldoni S, Fassan M, Serrero G, Gomella LG, Baffa R, Iozzo RV, Morrione A. Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth. The American Journal of Pathology. 174: 1037-47. PMID 19179604 DOI: 10.2353/Ajpath.2009.080735 |
0.356 |
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| 2009 |
Zhang G, Chen S, Goldoni S, Calder BW, Simpson HC, Owens RT, McQuillan DJ, Young MF, Iozzo RV, Birk DE. Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. The Journal of Biological Chemistry. 284: 8888-97. PMID 19136671 DOI: 10.1074/Jbc.M806590200 |
0.356 |
|
| 2009 |
Vecchione A, Fassan M, Anesti V, Morrione A, Goldoni S, Baldassarre G, Byrne D, D'Arca D, Palazzo JP, Lloyd J, Scorrano L, Gomella LG, Iozzo RV, Baffa R. MITOSTATIN , a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer Oncogene. 28: 257-269. PMID 18931701 DOI: 10.1038/Onc.2008.381 |
0.345 |
|
| 2009 |
Morrione A, Lovat F, Monami G, Bitto A, Xu S, Fassan M, Serrero G, Baffa R, Iozzo RV, Gomella LG. PROEPITHELIN IS A NOVEL BIOMARKER FOR PROSTATE CANCER AND REGULATES CELL GROWTH, MIGRATION AND ANCHORAGE-INDEPENDENT GROWTH OF PROSTATE CANCER CELLS Journal of Urology. 181: 512-512. DOI: 10.1016/S0022-5347(09)61445-2 |
0.309 |
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| 2008 |
Whitelock JM, Melrose J, Iozzo RV. Diverse cell signaling events modulated by perlecan. Biochemistry. 47: 11174-83. PMID 18826258 DOI: 10.1021/Bi8013938 |
0.413 |
|
| 2008 |
Goldoni S, Iozzo RV. Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs. International Journal of Cancer. 123: 2473-9. PMID 18798267 DOI: 10.1002/Ijc.23930 |
0.387 |
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| 2008 |
Goldoni S, Seidler DG, Heath J, Fassan M, Baffa R, Thakur ML, Owens RT, McQuillan DJ, Iozzo RV. An antimetastatic role for decorin in breast cancer. The American Journal of Pathology. 173: 844-55. PMID 18688028 DOI: 10.2353/Ajpath.2008.080275 |
0.379 |
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| 2008 |
Cailhier JF, Sirois I, Laplante P, Lepage S, Raymond MA, Brassard N, Prat A, Iozzo RV, Pshezhetsky AV, Hébert MJ. Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis. The Journal of Biological Chemistry. 283: 27220-9. PMID 18658137 DOI: 10.1074/Jbc.M801164200 |
0.31 |
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| 2008 |
Baker AB, Ettenson DS, Jonas M, Nugent MA, Iozzo RV, Edelman ER. Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circulation Research. 103: 289-97. PMID 18583708 DOI: 10.1161/Circresaha.108.179465 |
0.364 |
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| 2008 |
Bi X, Tong C, Dockendorff A, Bancroft L, Gallagher L, Guzman G, Iozzo RV, Augenlicht LH, Yang W. Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation. Carcinogenesis. 29: 1435-40. PMID 18550571 DOI: 10.1093/Carcin/Bgn141 |
0.365 |
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| 2008 |
Schaefer L, Iozzo RV. Biological functions of the small leucine-rich proteoglycans: From genetics to signal transduction Journal of Biological Chemistry. 283: 21305-21309. PMID 18463092 DOI: 10.1074/Jbc.R800020200 |
0.342 |
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| 2008 |
Zoeller JJ, McQuillan A, Whitelock J, Ho SY, Iozzo RV. A central function for perlecan in skeletal muscle and cardiovascular development. The Journal of Cell Biology. 181: 381-94. PMID 18426981 DOI: 10.1083/Jcb.200708022 |
0.707 |
|
| 2008 |
Bix G, Iozzo RV. Novel interactions of perlecan: unraveling perlecan's role in angiogenesis. Microscopy Research and Technique. 71: 339-48. PMID 18300285 DOI: 10.1002/Jemt.20562 |
0.36 |
|
| 2008 |
Zoeller JJ, Iozzo RV. Proteomic profiling of endorepellin angiostatic activity on human endothelial cells. Proteome Science. 6: 7. PMID 18269764 DOI: 10.1186/1477-5956-6-7 |
0.721 |
|
| 2008 |
Baffa R, Fassan M, Sevignani C, Vecchione A, Ishii H, Giarnieri E, Iozzo RV, Gomella LG, Croce CM. Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis. Carcinogenesis. 29: 846-8. PMID 18192690 DOI: 10.1093/Carcin/Bgn006 |
0.313 |
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| 2008 |
Woodall BP, Nyström A, Iozzo RA, Eble JA, Niland S, Krieg T, Eckes B, Pozzi A, Iozzo RV. Integrin α2β1 is the required receptor for endorepellin angiostatic activity Journal of Biological Chemistry. 283: 2335-2343. PMID 18024432 DOI: 10.1074/Jbc.M708364200 |
0.372 |
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| 2008 |
Fassan M, D'Arca D, Letko J, Vecchione A, Morrione A, Gardiman M, McCue P, Wildemore B, Rugge M, Shupp-Byrne D, Gomella LG, Iozzo RV, Baffa R. MITOSTATIN, A NOVEL MITOCHONDRIAL PROTEIN, THAT ACTS AS A TUMOR SUPPRESSOR IN PROSTATE CANCER CELLS Journal of Urology. 179: 458-458. DOI: 10.1016/S0022-5347(08)61344-0 |
0.351 |
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| 2008 |
Nystrom A, Shaik ZP, Pozzi A, Krieg T, Eckes B, Iozzo RV. Endorepellin evokes SHP1 activity in endothelial cells Matrix Biology. 27: 11-12. DOI: 10.1016/J.Matbio.2008.09.226 |
0.329 |
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| 2008 |
Whitelock J, Ma JL, Davies N, Nielsen N, Chuang C, Rees M, Iozzo RV, Knox S, Lord M. Recombinant heparan sulfate for use in tissue engineering applications Journal of Chemical Technology & Biotechnology. 83: 496-504. DOI: 10.1002/Jctb.1835 |
0.386 |
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| 2007 |
Ferdous Z, Wei VM, Iozzo R, Höök M, Grande-Allen KJ. Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. The Journal of Biological Chemistry. 282: 35887-98. PMID 17942398 DOI: 10.1074/Jbc.M705180200 |
0.334 |
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| 2007 |
Rühland C, Schönherr E, Robenek H, Hansen U, Iozzo RV, Bruckner P, Seidler DG. The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis. The Febs Journal. 274: 4246-55. PMID 17651433 DOI: 10.1111/J.1742-4658.2007.05951.X |
0.343 |
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| 2007 |
Schaefer L, Tsalastra W, Babelova A, Baliova M, Minnerup J, Sorokin L, Gröne HJ, Reinhardt DP, Pfeilschifter J, Iozzo RV, Schaefer RM. Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin. The American Journal of Pathology. 170: 301-15. PMID 17200203 DOI: 10.2353/Ajpath.2007.060497 |
0.32 |
|
| 2007 |
Bix G, Iozzo RA, Woodall B, Burrows M, McQuillan A, Campbell S, Fields GB, Iozzo RV. Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor. Blood. 109: 3745-8. PMID 17197432 DOI: 10.1182/Blood-2006-08-039925 |
0.319 |
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| 2007 |
Goldoni S, Iozzo RA, Kay P, Campbell S, McQuillan A, Agnew C, Zhu JX, Keene DR, Reed CC, Iozzo RV. A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity. Oncogene. 26: 368-81. PMID 16847455 DOI: 10.1038/Sj.Onc.1209803 |
0.383 |
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| 2006 |
Bix G, Castello R, Burrows M, Zoeller JJ, Weech M, Iozzo RA, Cardi C, Thakur ML, Barker CA, Camphausen K, Iozzo RV. Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism. Journal of the National Cancer Institute. 98: 1634-46. PMID 17105986 DOI: 10.1093/Jnci/Djj441 |
0.717 |
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| 2006 |
Laplante P, Raymond MA, Labelle A, Abe J, Iozzo RV, Hébert MJ. Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation. The Journal of Biological Chemistry. 281: 30383-92. PMID 16882656 DOI: 10.1074/Jbc.M606412200 |
0.327 |
|
| 2006 |
Monami G, Gonzalez EM, Hellman M, Gomella LG, Baffa R, Iozzo RV, Morrione A. Proepithelin promotes migration and invasion of 5637 bladder cancer cells through the activation of ERK1/2 and the formation of a paxillin/FAK/ERK complex. Cancer Research. 66: 7103-10. PMID 16849556 DOI: 10.1158/0008-5472.Can-06-0633 |
0.396 |
|
| 2006 |
Seidler DG, Goldoni S, Agnew C, Cardi C, Thakur ML, Owens RT, McQuillan DJ, Iozzo RV. Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation. The Journal of Biological Chemistry. 281: 26408-18. PMID 16835231 DOI: 10.1074/Jbc.M602853200 |
0.38 |
|
| 2006 |
Zhang G, Ezura Y, Chervoneva I, Robinson PS, Beason DP, Carine ET, Soslowsky LJ, Iozzo RV, Birk DE. Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development. Journal of Cellular Biochemistry. 98: 1436-49. PMID 16518859 DOI: 10.1002/Jcb.20776 |
0.339 |
|
| 2006 |
Sher I, Zisman-Rozen S, Eliahu L, Whitelock JM, Maas-Szabowski N, Yamada Y, Breitkreutz D, Fusenig NE, Arikawa-Hirasawa E, Iozzo RV, Bergman R, Ron D. Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation. The Journal of Biological Chemistry. 281: 5178-87. PMID 16269412 DOI: 10.1074/Jbc.M509500200 |
0.383 |
|
| 2006 |
HABURSKY K, TURNER K, BURROWS M, IOZZO R, CHOI S, DEGRADO W, SANANTONIO J. Endothelial cell_collagen interactions in angiogenesis Matrix Biology. 25: S58-S58. DOI: 10.1016/J.Matbio.2006.08.161 |
0.349 |
|
| 2006 |
BIX G, BURROWS M, CASTELLO R, ZOELLER J, IOZZO R, CARDI C, THAKUR M, IOZZO R. Actin' Up: Endorepellin and endothelial morphogenesis Matrix Biology. 25: S58-S58. DOI: 10.1016/J.Matbio.2006.08.160 |
0.692 |
|
| 2005 |
Goldberg M, Septier D, Rapoport O, Iozzo RV, Young MF, Ameye LG. Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation. Calcified Tissue International. 77: 297-310. PMID 16283572 DOI: 10.1007/S00223-005-0026-7 |
0.319 |
|
| 2005 |
Iozzo RV. Basement membrane proteoglycans: from cellar to ceiling. Nature Reviews. Molecular Cell Biology. 6: 646-56. PMID 16064139 DOI: 10.1038/Nrm1702 |
0.306 |
|
| 2005 |
Zhu JX, Goldoni S, Bix G, Owens RT, McQuillan DJ, Reed CC, Iozzo RV. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. The Journal of Biological Chemistry. 280: 32468-79. PMID 15994311 DOI: 10.1074/Jbc.M503833200 |
0.343 |
|
| 2005 |
Bi Y, Stuelten CH, Kilts T, Wadhwa S, Iozzo RV, Robey PG, Chen XD, Young MF. Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. The Journal of Biological Chemistry. 280: 30481-9. PMID 15964849 DOI: 10.1074/Jbc.M500573200 |
0.321 |
|
| 2005 |
Seidler DG, Schaefer L, Robenek H, Iozzo RV, Kresse H, Schönherr E. A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival. Biochemical and Biophysical Research Communications. 332: 1162-70. PMID 15949467 DOI: 10.1016/J.Bbrc.2005.04.175 |
0.353 |
|
| 2005 |
Schönherr E, Sunderkötter C, Iozzo RV, Schaefer L. Decorin, a novel player in the insulin-like growth factor system. The Journal of Biological Chemistry. 280: 15767-72. PMID 15701628 DOI: 10.1074/Jbc.M500451200 |
0.359 |
|
| 2005 |
Reed CC, Waterhouse A, Kirby S, Kay P, Owens RT, McQuillan DJ, Iozzo RV. Decorin prevents metastatic spreading of breast cancer. Oncogene. 24: 1104-10. PMID 15690056 DOI: 10.1038/Sj.Onc.1208329 |
0.331 |
|
| 2005 |
Bix G, Iozzo RV. Matrix revolutions: "tails" of basement-membrane components with angiostatic functions. Trends in Cell Biology. 15: 52-60. PMID 15653078 DOI: 10.1016/J.Tcb.2004.11.008 |
0.382 |
|
| 2005 |
Gonzalez EM, Reed CC, Bix G, Fu J, Zhang Y, Gopalakrishnan B, Greenspan DS, Iozzo RV. BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan Journal of Biological Chemistry. 280: 7080-7087. PMID 15591058 DOI: 10.1074/Jbc.M409841200 |
0.343 |
|
| 2004 |
Schönherr E, Sunderkötter C, Schaefer L, Thanos S, Grässel S, Oldberg A, Iozzo RV, Young MF, Kresse H. Decorin deficiency leads to impaired angiogenesis in injured mouse cornea Journal of Vascular Research. 41: 499-508. PMID 15528932 DOI: 10.1159/000081806 |
0.397 |
|
| 2004 |
Schaefer L, Mihalik D, Babelova A, Krzyzankova M, Gröne HJ, Iozzo RV, Young MF, Seidler DG, Lin G, Reinhardt DP, Schaefer RM. Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury. The American Journal of Pathology. 165: 383-96. PMID 15277214 DOI: 10.1016/S0002-9440(10)63305-6 |
0.304 |
|
| 2004 |
Goldoni S, Owens RT, McQuillan DJ, Shriver Z, Sasisekharan R, Birk DE, Campbell S, Iozzo RV. Biologically active decorin is a monomer in solution. The Journal of Biological Chemistry. 279: 6606-12. PMID 14660661 DOI: 10.1074/Jbc.M310342200 |
0.337 |
|
| 2004 |
Reed CC, Iozzo RV. The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconjugate Journal. 19: 249-55. PMID 12975602 DOI: 10.1023/A:1025383913444 |
0.329 |
|
| 2003 |
Gonzalez EM, Mongiat M, Slater SJ, Baffa R, Iozzo RV. A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth. The Journal of Biological Chemistry. 278: 38113-6. PMID 12900424 DOI: 10.1074/Jbc.C300310200 |
0.393 |
|
| 2003 |
Sweeney SM, DiLullo G, Slater SJ, Martinez J, Iozzo RV, Lauer-Fields JL, Fields GB, San Antonio JD. Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly. The Journal of Biological Chemistry. 278: 30516-24. PMID 12788934 DOI: 10.1074/Jbc.M304237200 |
0.344 |
|
| 2003 |
Kalabis J, Patterson MJ, Enders GH, Marian B, Iozzo RV, Rogler G, Gimotty PA, Herlyn M. Stimulation of human colonic epithelial cells by leukemia inhibitory factor is dependent on collagen-embedded fibroblasts in organotypic culture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1115-7. PMID 12692084 DOI: 10.1096/Fj.02-0852Fje |
0.386 |
|
| 2003 |
Tralhão JG, Schaefer L, Micegova M, Evaristo C, Schönherr E, Kayal S, Veiga-Fernandes H, Danel C, Iozzo RV, Kresse H, Lemarchand P. In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 464-6. PMID 12631584 DOI: 10.1096/Fj.02-0534Fje |
0.372 |
|
| 2003 |
Mongiat M, Fu J, Oldershaw R, Greenhalgh R, Gown AM, Iozzo RV. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. The Journal of Biological Chemistry. 278: 17491-9. PMID 12604605 DOI: 10.1074/Jbc.M210529200 |
0.423 |
|
| 2003 |
Mongiat M, Sweeney SM, San Antonio JD, Fu J, Iozzo RV. Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan. The Journal of Biological Chemistry. 278: 4238-49. PMID 12435733 DOI: 10.1074/Jbc.M210445200 |
0.398 |
|
| 2003 |
Ghiselli G, Eichstetter I, Iozzo RV. A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor. The Biochemical Journal. 359: 153-63. PMID 11563979 DOI: 10.1042/0264-6021:3590153 |
0.415 |
|
| 2002 |
Rosini P, Bonaccorsi L, Baldi E, Chiasserini C, Forti G, De Chiara G, Lucibello M, Mongiat M, Iozzo RV, Garaci E, Cozzolino F, Torcia MG. Androgen receptor expression induces FGF2, FGF-binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth, survival, and androgen receptor down-modulation. The Prostate. 53: 310-21. PMID 12430142 DOI: 10.1002/Pros.10164 |
0.338 |
|
| 2002 |
Santra M, Reed CC, Iozzo RV. Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope. The Journal of Biological Chemistry. 277: 35671-81. PMID 12105206 DOI: 10.1074/Jbc.M205317200 |
0.316 |
|
| 2002 |
Grant DS, Yenisey C, Rose RW, Tootell M, Santra M, Iozzo RV. Decorin suppresses tumor cell-mediated angiogenesis. Oncogene. 21: 4765-77. PMID 12101415 DOI: 10.1038/Sj.Onc.1205595 |
0.414 |
|
| 2002 |
Reed CC, Gauldie J, Iozzo RV. Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene. 21: 3688-95. PMID 12032837 DOI: 10.1038/Sj.Onc.1205470 |
0.371 |
|
| 2002 |
Schaefer L, Macakova K, Raslik I, Micegova M, Gröne HJ, Schönherr E, Robenek H, Echtermeyer FG, Grässel S, Bruckner P, Schaefer RM, Iozzo RV, Kresse H. Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction. The American Journal of Pathology. 160: 1181-91. PMID 11891213 DOI: 10.1016/S0002-9440(10)64937-1 |
0.358 |
|
| 2001 |
Iozzo RV, Antonio JDS. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena. Journal of Clinical Investigation. 108: 349-355. PMID 11489925 DOI: 10.1172/Jci13738 |
0.392 |
|
| 2001 |
Iozzo RV. Series Introduction: Heparan sulfate proteoglycans: intricate molecules with intriguing functions Journal of Clinical Investigation. 108: 165-167. PMID 11457866 DOI: 10.1172/Jci13560 |
0.31 |
|
| 2001 |
Powzaniuk MA, Trotta R, Loza MJ, Harth A, Iozzo RV, Eisenlohr LC, Perussia B, Calabretta B. B-Myb overexpression results in activation and increased Fas/Fas ligand-mediated cytotoxicity of T and NK cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 242-9. PMID 11418655 DOI: 10.4049/Jimmunol.167.1.242 |
0.322 |
|
| 2001 |
Demoor-Fossard M, Galéra P, Santra M, Iozzo RV, Pujol JP, Rédini F. A composite element binding the vitamin D receptor and the retinoic X receptor alpha mediates the transforming growth factor-beta inhibition of decorin gene expression in articular chondrocytes. The Journal of Biological Chemistry. 276: 36983-92. PMID 11406617 DOI: 10.1074/Jbc.M011442200 |
0.305 |
|
| 2001 |
Mongiat M, Otto J, Oldershaw R, Ferrer F, Sato JD, Iozzo RV. Fibroblast growth factor-binding protein is a novel partner for perlecan protein core. The Journal of Biological Chemistry. 276: 10263-71. PMID 11148217 DOI: 10.1074/Jbc.M011493200 |
0.349 |
|
| 2001 |
Santra M, Eichstetter I, Iozzo RV. An anti-oncogenic role for decorin. Down-regulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells. The Journal of Biological Chemistry. 275: 35153-61. PMID 10942781 DOI: 10.1074/Jbc.M006821200 |
0.404 |
|
| 2001 |
GHISELLI G, EICHSTETTER I, IOZZO RV. A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor Biochemical Journal. 359: 153-163. DOI: 10.1042/bj3590153 |
0.3 |
|
| 2000 |
Csordás G, Santra M, Reed CC, Eichstetter I, McQuillan DJ, Gross D, Nugent MA, Hajnóczky G, Iozzo RV. Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo. The Journal of Biological Chemistry. 275: 32879-87. PMID 10913155 DOI: 10.1074/Jbc.M005609200 |
0.336 |
|
| 2000 |
Nugent MA, Nugent HM, Iozzo RV, Sanchack K, Edelman ER. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia. Proceedings of the National Academy of Sciences of the United States of America. 97: 6722-7. PMID 10841569 DOI: 10.1073/Pnas.97.12.6722 |
0.393 |
|
| 2000 |
Keene DR, San Antonio JD, Mayne R, McQuillan DJ, Sarris G, Santoro SA, Iozzo RV. Decorin binds near the C terminus of type I collagen. The Journal of Biological Chemistry. 275: 21801-4. PMID 10823816 DOI: 10.1074/Jbc.C000278200 |
0.314 |
|
| 2000 |
Fuki IV, Iozzo RV, Williams KJ. Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism. The Journal of Biological Chemistry. 275: 25742-50. PMID 10818109 DOI: 10.1074/Jbc.M909173199 |
0.335 |
|
| 2000 |
Ghiselli G, Iozzo RV. Overexpression of bamacan/SMC3 causes transformation. The Journal of Biological Chemistry. 275: 20235-8. PMID 10801778 DOI: 10.1074/Jbc.C000213200 |
0.361 |
|
| 2000 |
Mongiat M, Taylor K, Otto J, Aho S, Uitto J, Whitelock JM, Iozzo RV. The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7. The Journal of Biological Chemistry. 275: 7095-100. PMID 10702276 DOI: 10.1074/Jbc.275.10.7095 |
0.366 |
|
| 2000 |
Nugent MA, Iozzo RV. Fibroblast growth factor-2 International Journal of Biochemistry and Cell Biology. 32: 115-120. PMID 10687947 DOI: 10.1016/S1357-2725(99)00123-5 |
0.389 |
|
| 1999 |
Whitelock JM, Graham LD, Melrose J, Murdoch AD, Iozzo RV, Underwood PA. Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells. Matrix Biology : Journal of the International Society For Matrix Biology. 18: 163-78. PMID 10372557 DOI: 10.1016/S0945-053X(99)00014-1 |
0.394 |
|
| 1999 |
Ghiselli G, Siracusa LD, Iozzo RV. Complete cDNA cloning, genomic organization, chromosomal assignment, functional characterization of the promoter, and expression of the murine Bamacan gene. The Journal of Biological Chemistry. 274: 17384-93. PMID 10358101 DOI: 10.1074/Jbc.274.24.17384 |
0.346 |
|
| 1999 |
Iozzo RV, Chakrani F, Perrotti D, McQuillan DJ, Skorski T, Calabretta B, Eichstetter I. Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 96: 3092-7. PMID 10077642 DOI: 10.1073/Pnas.96.6.3092 |
0.355 |
|
| 1999 |
Iozzo RV, Moscatello DK, McQuillan DJ, Eichstetter I. Decorin Is a Biological Ligand for the Epidermal Growth Factor Receptor Journal of Biological Chemistry. 274: 4489-4492. PMID 9988678 DOI: 10.1074/Jbc.274.8.4489 |
0.347 |
|
| 1998 |
Iozzo RV, Danielson KG. Transcriptional and Posttranscriptional Regulation of Proteoglycan Gene Expression Progress in Nucleic Acid Research and Molecular Biology. 62: 19-53. PMID 9932451 DOI: 10.1016/S0079-6603(08)60504-8 |
0.369 |
|
| 1998 |
Fleischmajer R, Perlish JS, MacDonald ED, Schechter A, Murdoch AD, Iozzo RV, Yamada Y. There is binding of collagen IV to beta 1 integrin during early skin basement membrane assembly. Annals of the New York Academy of Sciences. 857: 212-27. PMID 9917843 DOI: 10.1111/J.1749-6632.1998.Tb10118.X |
0.307 |
|
| 1998 |
Sharma B, Handler M, Eichstetter I, Whitelock JM, Nugent MA, Iozzo RV. Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo. The Journal of Clinical Investigation. 102: 1599-608. PMID 9788974 DOI: 10.1172/Jci3793 |
0.391 |
|
| 1998 |
Iozzo RV. Matrix Proteoglycans: From Molecular Design to Cellular Function Annual Review of Biochemistry. 67: 609-652. PMID 9759499 DOI: 10.1146/Annurev.Biochem.67.1.609 |
0.398 |
|
| 1998 |
Kovalszky I, Dudás J, Oláh-Nagy J, Pogány G, Töváry J, Timár J, Kopper L, Jeney A, Iozzo RV. Inhibition of DNA topoisomerase I activity by heparan sulfate and modulation by basic fibroblast growth factor. Molecular and Cellular Biochemistry. 183: 11-23. PMID 9655174 DOI: 10.1023/A:1006898920637 |
0.309 |
|
| 1998 |
Sharma B, Iozzo RV. Transcriptional silencing of perlecan gene expression by interferon-gamma. The Journal of Biological Chemistry. 273: 4642-6. PMID 9468523 DOI: 10.1074/Jbc.273.8.4642 |
0.35 |
|
| 1998 |
Patel S, Santra M, McQuillan DJ, Iozzo RV, Thomas AP. Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells. The Journal of Biological Chemistry. 273: 3121-4. PMID 9452417 DOI: 10.1074/Jbc.273.6.3121 |
0.339 |
|
| 1998 |
Kyriakides TR, Zhu YH, Smith LT, Bain SD, Yang Z, Lin MT, Danielson KG, Iozzo RV, LaMarca M, McKinney CE, Ginns EI, Bornstein P. Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis Journal of Cell Biology. 140: 419-430. PMID 9442117 DOI: 10.1083/Jcb.140.2.419 |
0.344 |
|
| 1998 |
Moscatello DK, Santra M, Mann DM, McQuillan DJ, Wong AJ, Iozzo RV. Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor. The Journal of Clinical Investigation. 101: 406-12. PMID 9435313 DOI: 10.1172/Jci846 |
0.389 |
|
| 1997 |
Kovalszky, Nagy JO, Gallai M, Sebestyén A, Schaff Z, Paku S, Jeney A, Iozzo RV. Altered Proteoglycan Gene Expression in Human Biliary Cirrhosis. Pathology Oncology Research : Por. 3: 51-58. PMID 11173626 DOI: 10.1007/Bf02893354 |
0.325 |
|
| 1997 |
Handler M, Yurchenco PD, Iozzo RV. Developmental expression of perlecan during murine embryogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 210: 130-45. PMID 9337134 DOI: 10.1002/(Sici)1097-0177(199710)210:2<130::Aid-Aja6>3.0.Co;2-H |
0.35 |
|
| 1997 |
Fuki IV, Kuhn KM, Lomazov IR, Rothman VL, Tuszynski GP, Iozzo RV, Swenson TL, Fisher EA, Williams KJ. The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro. The Journal of Clinical Investigation. 100: 1611-22. PMID 9294130 DOI: 10.1172/Jci119685 |
0.336 |
|
| 1997 |
Santra M, Mann DM, Mercer EW, Skorski T, Calabretta B, Iozzo RV. Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases. The Journal of Clinical Investigation. 100: 149-57. PMID 9202067 DOI: 10.1172/Jci119507 |
0.389 |
|
| 1997 |
Iozzo RV. The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth. Critical Reviews in Biochemistry and Molecular Biology. 32: 141-174. PMID 9145286 DOI: 10.3109/10409239709108551 |
0.395 |
|
| 1997 |
Aviezer D, Iozzo RV, Noonan DM, Yayon A. Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA. Molecular and Cellular Biology. 17: 1938-46. PMID 9121441 DOI: 10.1128/Mcb.17.4.1938 |
0.406 |
|
| 1997 |
DeRocco SE, Iozzo R, Ma XP, Schwarting R, Peterson D, Calabretta B. Ectopic expression of A-myb in transgenic mice causes follicular hyperplasia and enhanced B lymphocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America. 94: 3240-4. PMID 9096377 DOI: 10.1073/Pnas.94.7.3240 |
0.331 |
|
| 1997 |
Iozzo RV, Pillarisetti J, Sharma B, Murdoch AD, Danielson KG, Uitto J, Mauviel A. Structural and Functional Characterization of the Human Perlecan Gene Promoter TRANSCRIPTIONAL ACTIVATION BY TRANSFORMING GROWTH FACTOR-β VIA A NUCLEAR FACTOR 1-BINDING ELEMENT Journal of Biological Chemistry. 272: 5219-5228. PMID 9030592 DOI: 10.1074/Jbc.272.8.5219 |
0.339 |
|
| 1997 |
Skorski T, Nieborowska-Skorska M, Wlodarski P, Perrotti D, Hoser G, Kawiak J, Majewski M, Christensen L, Iozzo RV, Calabretta B. Treatment of Philadelphia leukemia in severe combined immunodeficient mice by combination of cyclophosphamide and bcr/abl antisense oligodeoxynucleotides. Journal of the National Cancer Institute. 89: 124-33. PMID 8998181 DOI: 10.1093/Jnci/89.2.124 |
0.306 |
|
| 1997 |
Weber IT, Harrison RW, Iozzo RV. Model structure of decorin and implications for collagen fibrillogenesis. The Journal of Biological Chemistry. 271: 31767-70. PMID 8943211 DOI: 10.1074/Jbc.271.50.31767 |
0.316 |
|
| 1997 |
Santra M, Mann DM, Mercer EW, Skorski T, Calabretta B, Iozzo RV. Ectopic expression of decorin protein core causes generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases Matrix Biology. 16: 121. DOI: 10.1016/S0945-053X(97)90047-0 |
0.334 |
|
| 1996 |
De Luca A, Santra M, Baldi A, Giordano A, Iozzo RV. Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases. The Journal of Biological Chemistry. 271: 18961-5. PMID 8702560 DOI: 10.1074/Jbc.271.31.18961 |
0.37 |
|
| 1996 |
Skorski T, Nieborowska-Skorska M, Campbell K, Iozzo RV, Zon G, Darzynkiewicz Z, Calabretta B. Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes. The Journal of Experimental Medicine. 182: 1645-53. PMID 7500009 DOI: 10.1084/Jem.182.6.1645 |
0.322 |
|
| 1996 |
Skorski T, Nieborowska-Skorska M, Wlodarski P, Zon G, Iozzo R, Calabretta B. Antisense oligodeoxynucleotide combination therapy of primary chronic myelogenous leukemia blast crisis in SCID mice Blood. 88: 1005-1012. DOI: 10.1182/Blood.V88.3.1005.1005 |
0.324 |
|
| 1995 |
Wegrowski Y, Pillarisetti J, Danielson KG, Suzuki S, Iozzo RV. The murine biglycan: complete cDNA cloning, genomic organization, promoter function, and expression. Genomics. 30: 8-17. PMID 8595907 DOI: 10.1006/Geno.1995.0002 |
0.307 |
|
| 1995 |
Danielson KG, Pillarisetti J, Cohen IR, Sholehvar B, Huebner K, Ng LJ, Nicholls JM, Cheah KSE, Iozzo RV. Characterization of the complete genomic structure of the human WNT-5A gene, functional analysis of its promoter, chromosomal mapping, and expression in early human embryogenesis Journal of Biological Chemistry. 270: 31225-31234. PMID 8537388 DOI: 10.1074/Jbc.270.52.31225 |
0.326 |
|
| 1995 |
Naso MF, Morgan JL, Buchberg AM, Siracusa LD, Iozzo RV. Expression pattern and mapping of the murine versican gene (Cspg2) to chromosome 13. Genomics. 29: 297-300. PMID 8530092 DOI: 10.1006/Geno.1995.1251 |
0.318 |
|
| 1995 |
Mauviel A, Santra M, Chen YQ, Uitto J, Iozzo RV. Transcriptional regulation of decorin gene expression. Induction by quiescence and repression by tumor necrosis factor-alpha. The Journal of Biological Chemistry. 270: 11692-700. PMID 7744809 DOI: 10.1074/Jbc.270.19.11692 |
0.331 |
|
| 1995 |
Santra M, Skorski T, Calabretta B, Lattime EC, Iozzo RV. De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 7016-20. PMID 7624361 DOI: 10.1073/Pnas.92.15.7016 |
0.422 |
|
| 1995 |
Grässel S, Cohen IR, Murdoch AD, Eichstetter I, Iozzo RV. The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester. Molecular and Cellular Biochemistry. 145: 61-8. PMID 7544867 DOI: 10.1007/Bf00925714 |
0.344 |
|
| 1995 |
Baribault H, Penner J, Iozzo RV, Wilson-Heiner M. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes & Development. 8: 2964-73. PMID 7528156 DOI: 10.1101/Gad.8.24.2964 |
0.309 |
|
| 1994 |
Skorski T, Nieborowska-Skorska M, Nicolaides NC, Szczylik C, Iversen P, Iozzo RV, Zon G, Calabretta B. Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide. Proceedings of the National Academy of Sciences of the United States of America. 91: 4504-8. PMID 8183938 DOI: 10.1073/Pnas.91.10.4504 |
0.307 |
|
| 1994 |
Reginato AM, Iozzo RV, Jimenez SA. Formation of nodular structures resembling mature articular cartilage in long-term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate. Arthritis and Rheumatism. 37: 1338-49. PMID 7945499 DOI: 10.1002/Art.1780370912 |
0.301 |
|
| 1994 |
Iozzo RV. Perlecan: A gem of a proteoglycan Matrix Biology. 14: 203-208. PMID 7921536 DOI: 10.1016/0945-053X(94)90183-X |
0.324 |
|
| 1994 |
Murdoch AD, Liu B, Schwarting R, Tuan RS, Iozzo RV. Widespread expression of perlecan proteoglycan in basement membranes and extracellular matrices of human tissues as detected by a novel monoclonal antibody against Domain III and by in situ hybridization Journal of Histochemistry and Cytochemistry. 42: 239-249. PMID 7507142 DOI: 10.1177/42.2.7507142 |
0.335 |
|
| 1993 |
Iozzo RV, Cohen I. Altered proteoglycan gene expression and the tumor stroma. Experientia. 49: 447-55. PMID 8500599 DOI: 10.1007/Bf01923588 |
0.367 |
|
| 1993 |
Danielson KG, Fazzio A, Cohen I, Cannizzaro LA, Eichstetter I, Iozzo RV. The Human Decorin Gene: Intron-Exon Organization, Discovery of Two Alternatively Spliced Exons in the 5′ Untranslated Region, and Mapping of the Gene to Chromosome 12q23 Genomics. 15: 146-160. PMID 8432526 DOI: 10.1006/Geno.1993.1022 |
0.306 |
|
| 1993 |
Cohen IR, Grässel S, Murdoch AD, Iozzo RV. Structural characterization of the complete human perlecan gene and its promoter. Proceedings of the National Academy of Sciences of the United States of America. 90: 10404-8. PMID 8234307 DOI: 10.1073/Pnas.90.21.10404 |
0.309 |
|
| 1992 |
Alvarez RJ, Sun MJ, Haverty TP, Iozzo RV, Myers JC, Neilson EG. Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines. Kidney International. 41: 14-23. PMID 1593850 DOI: 10.1038/Ki.1992.3 |
0.31 |
|
| 1992 |
Danielson KG, Martinez-Hernandez A, Hassell JR, Iozzo RV. Establishment of a cell line from the EHS tumor: biosynthesis of basement membrane constituents and characterization of a hybrid proteoglycan containing heparan and chondroitin sulfate chains. Matrix (Stuttgart, Germany). 12: 22-35. PMID 1560787 DOI: 10.1016/S0934-8832(11)80101-0 |
0.359 |
|
| 1991 |
Dodge GR, Kovalszky I, Chu ML, Hassell JR, McBride OW, Yi HF, Iozzo RV. Heparan sulfate proteoglycan of human colon: partial molecular cloning, cellular expression, and mapping of the gene (HSPG2) to the short arm of human chromosome 1. Genomics. 10: 673-80. PMID 1679749 DOI: 10.1016/0888-7543(91)90451-J |
0.307 |
|
| 1990 |
Kaner RJ, Iozzo RV, Ziaie Z, Kefalides NA. Inhibition of proteoglycan synthesis in human endothelial cells after infection with herpes simplex virus type 1 in vitro. American Journal of Respiratory Cell and Molecular Biology. 2: 423-31. PMID 2160254 DOI: 10.1165/Ajrcmb/2.5.423 |
0.321 |
|
| 1989 |
Ben-Rafael Z, Benadiva CA, Mastroianni L, Garcia CJ, Minda JM, Iozzo RV, Flickinger GL. Collagen matrix influences the morphologic features and steroid secretion of human granulosa cells. American Journal of Obstetrics and Gynecology. 159: 1570-4. PMID 3207133 DOI: 10.1016/0002-9378(88)90596-0 |
0.35 |
|
| 1989 |
Tan EM, Levine E, Sorger T, Unger GA, Hacobian N, Planck B, Iozzo RV. Heparin and endothelial cell growth factor modulate collagen and proteoglycan production in human smooth muscle cells. Biochemical and Biophysical Research Communications. 163: 84-92. PMID 2775295 DOI: 10.1016/0006-291X(89)92102-5 |
0.364 |
|
| 1989 |
Iozzo RV, Sampson PM, Schmitt GK. Neoplastic modulation of extracellular matrix: stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co-cultures of human colon carcinoma and smooth muscle cells. Journal of Cellular Biochemistry. 39: 355-78. PMID 2722966 DOI: 10.1002/Jcb.240390403 |
0.342 |
|
| 1989 |
Iozzo RV, Hassell JR. Identification of the precursor protein for the heparan sulfate proteoglycan of human colon carcinoma cells and its post-translational modifications. Archives of Biochemistry and Biophysics. 269: 239-249. PMID 2521785 DOI: 10.1016/0003-9861(89)90105-7 |
0.331 |
|
| 1988 |
Iozzo RV. Proteoglycans and neoplasia. Cancer Metastasis Reviews. 7: 39-50. PMID 3293831 DOI: 10.1007/Bf00048277 |
0.404 |
|
| 1988 |
Iozzo RV. Cell surface heparan sulfate proteoglycan and the neoplastic phenotype. Journal of Cellular Biochemistry. 37: 61-78. PMID 2968986 DOI: 10.1002/Jcb.240370107 |
0.393 |
|
| 1986 |
Iozzo RV, Ketterer CL, Slaymaker DJ. Evidence of a small hydrophobic domain in the core protein of the heparan sulfate proteoglycan from human colon carcinoma cells. Febs Letters. 206: 304-8. PMID 2944764 DOI: 10.1016/0014-5793(86)81001-8 |
0.321 |
|
| 1986 |
Uri AK, Wetmore RF, Iozzo RV. Glycogen-rich clear cell carcinoma in the tongue. A cytochemical and ultrastructural study. Cancer. 57: 1803-9. PMID 2420437 DOI: 10.1002/1097-0142(19860501)57:9<1803::Aid-Cncr2820570916>3.0.Co;2-E |
0.317 |
|
| 1984 |
Iozzo RV. Biosynthesis of heparan sulfate proteoglycan by human colon carcinoma cells and its localization at the cell surface. The Journal of Cell Biology. 99: 403-17. PMID 6235235 DOI: 10.1083/Jcb.99.2.403 |
0.33 |
|
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