Andras Kapus - Publications

Affiliations: 
Medical Science University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Oncology, Cell Biology

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Year Citation  Score
2019 Yeung T, Fung O, Bashkurov M, Khandani A, Subedar O, Wudwud A, Shaw P, Clarke B, Bartlett J, Rottapel R, Kapus A. Avoidance of apoptotic death via a hyperploid salvage survival pathway after platinum treatment in high grade serous carcinoma cell line models. Oncotarget. 10: 6691-6712. PMID 31803363 DOI: 10.18632/Oncotarget.27330  0.308
2019 Dan Q, Shi Y, Rabani R, Venugopal S, Xiao J, Anwer S, Ding M, Speight P, Pan W, Alexander RT, Kapus A, Szászi K. Claudin-2 suppresses GEF-H1, RHOA, and MRTF thereby impacting proliferation and profibrotic phenotype of tubular cells. The Journal of Biological Chemistry. PMID 31481470 DOI: 10.1074/Jbc.Ra118.006484  0.435
2019 Demian WL, Persaud A, Jiang C, Coyaud É, Liu S, Kapus A, Kafri R, Raught B, Rotin D. The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1. Cell Reports. 27: 1886-1896.e6. PMID 31067471 DOI: 10.1016/J.Celrep.2019.04.034  0.381
2019 Bialik JF, Ding M, Speight P, Dan Q, Miranda MZ, Di Ciano-Oliveira C, Kofler MM, Rotstein OD, Pedersen SF, Szászi K, Kapus A. Profibrotic epithelial phenotype: a central role for MRTF and TAZ. Scientific Reports. 9: 4323. PMID 30867502 DOI: 10.1038/S41598-019-40764-7  0.394
2018 Kofler M, Speight P, Little D, Di Ciano-Oliveira C, Szászi K, Kapus A. Mediated nuclear import and export of TAZ and the underlying molecular requirements. Nature Communications. 9: 4966. PMID 30470756 DOI: 10.1038/S41467-018-07450-0  0.355
2018 Safavian D, Leung CH, Kapus A, Ailenberg M, Szaszi K, Shani R, Di Ciano-Oliveira C, Ghazerian M, Rotstein O. Hemorrhagic Shock/Resuscitation Reduces the M2 Phenotype of Alveolar Macrophages: A Potential Mechanism Contributing to Increased LPS-Induced Lung Injury. Shock (Augusta, Ga.). PMID 29489738 DOI: 10.1097/Shk.0000000000001135  0.315
2017 Amoozadeh Y, Anwer S, Dan Q, Venugopal S, Shi Y, Branchard E, Liedtke E, Ailenberg M, Rotstein OD, Kapus A, Szaszi K. Cell confluence regulates claudin-2 expression: possible role for ZO-1 and Rac. American Journal of Physiology. Cell Physiology. ajpcell.00234.2017. PMID 29187366 DOI: 10.1152/Ajpcell.00234.2017  0.404
2017 Miranda MZ, Bialik JF, Speight P, Dan Q, Yeung T, Szászi K, Pedersen SF, Kapus A. TGF-β1 regulates the expression and transcriptional activity of TAZ via a Smad3-independent, myocardin-related transcription factor-mediated mechanism. The Journal of Biological Chemistry. PMID 28739802 DOI: 10.1074/Jbc.M117.780502  0.435
2017 Zhang Y, Connelly KA, Thai K, Wu X, Kapus A, Kepecs D, Gilbert RE. Sirtuin 1 Activation Reduces Transforming Growth Factor-β1-Induced Fibrogenesis and Affords Organ Protection in a Model of Progressive, Experimental Kidney and Associated Cardiac Disease. The American Journal of Pathology. 187: 80-90. PMID 27993241 DOI: 10.1016/J.Ajpath.2016.09.016  0.301
2016 Moodley S, Derouet M, Bai XH, Xu F, Kapus A, Yang BB, Liu M. Stimulus-dependent dissociation between XB130 and Tks5 scaffold proteins promotes airway epithelial cell migration. Oncotarget. PMID 27835612 DOI: 10.18632/Oncotarget.13261  0.392
2016 Speight P, Kofler M, Szászi K, Kapus A. Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3. Nature Communications. 7: 11642. PMID 27189435 DOI: 10.1038/Ncomms11642  0.373
2016 Tsang JL, Jia SH, Parodo J, Plant P, Lodyga M, Charbonney E, Szaszi K, Kapus A, Marshall JC. Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src. Plos One. 11: e0153946. PMID 27101103 DOI: 10.1371/Journal.Pone.0153946  0.7
2016 Szeto SG, Narimatsu M, Lu M, He X, Sidiqi AM, Tolosa MF, Chan L, De Freitas K, Bialik JF, Majumder S, Boo S, Hinz B, Dan Q, Advani A, John R, ... ... Kapus A, et al. YAP/TAZ Are Mechanoregulators of TGF-β-Smad Signaling and Renal Fibrogenesis. Journal of the American Society of Nephrology : Jasn. PMID 26961347 DOI: 10.1681/Asn.2015050499  0.305
2016 Rozycki M, Bialik JF, Speight P, Dan Q, Knudsen TE, Szeto SG, Yuen DA, Szászi K, Pedersen SF, Kapus A. Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE. The Journal of Biological Chemistry. 291: 227-43. PMID 26555261 DOI: 10.1074/Jbc.M115.674606  0.397
2015 Moodley S, Hui Bai X, Kapus A, Yang B, Liu M. XB130/Tks5 scaffold protein interaction regulates Src-mediated cell proliferation and survival. Molecular Biology of the Cell. PMID 26446840 DOI: 10.1091/Mbc.E15-07-0483  0.408
2015 Yin J, Michalick L, Tang C, Tabuchi A, Goldenberg N, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles-Kursar G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, ... ... Kapus A, et al. Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 26222277 DOI: 10.1165/Rcmb.2014-0225Oc  0.374
2015 Talele NP, Fradette J, Davies JE, Kapus A, Hinz B. Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells. Stem Cell Reports. 4: 1016-30. PMID 26028530 DOI: 10.1016/J.Stemcr.2015.05.004  0.303
2015 Tawadros PS, Powers KA, Ailenberg M, Birch SE, Marshall JC, Szaszi K, Kapus A, Rotstein OD. Oxidative Stress Increases Surface Toll-Like Receptor 4 Expression in Murine Macrophages via Ceramide Generation. Shock (Augusta, Ga.). PMID 25944793 DOI: 10.1097/Shk.0000000000000392  0.406
2015 Ailenberg M, Di Ciano-Oliveira C, Szaszi K, Dan Q, Rozycki M, Kapus A, Rotstein OD. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. British Journal of Pharmacology. 172: 3748-63. PMID 25850711 DOI: 10.1111/Bph.13162  0.378
2015 Zabini D, Kapus A, Kuebler W. SMAD3 regulation contributes to lung vascular remodeling in pulmonary arterial hypertension European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Oa3496  0.338
2014 Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, et al. Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness. The American Journal of Pathology. 184: 1489-502. PMID 24650563 DOI: 10.1016/J.Ajpath.2014.01.016  0.344
2014 Jia SH, Parodo J, Charbonney E, Tsang JL, Jia SY, Rotstein OD, Kapus A, Marshall JC. Activated neutrophils induce epithelial cell apoptosis through oxidant-dependent tyrosine dephosphorylation of caspase-8. The American Journal of Pathology. 184: 1030-40. PMID 24589337 DOI: 10.1016/J.Ajpath.2013.12.031  0.73
2014 Rozycki M, Lodyga M, Lam J, Miranda MZ, Fátyol K, Speight P, Kapus A. The fate of the primary cilium during myofibroblast transition. Molecular Biology of the Cell. 25: 643-57. PMID 24403605 DOI: 10.1091/Mbc.E13-07-0429  0.338
2013 Charbonney E, Speight P, Kapus A. How do your contacts (or their absence) shape your fate? Tissue Barriers. 1: e23699. PMID 24665378 DOI: 10.4161/Tisb.23699  0.367
2013 Speight P, Nakano H, Kelley TJ, Hinz B, Kapus A. Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition. Molecular Biology of the Cell. 24: 3326-36. PMID 24006486 DOI: 10.1091/Mbc.E13-04-0220  0.336
2013 Kapus A, Janmey P. Plasma membrane-cortical cytoskeleton interactions: A cell biology approach with biophysical considerations Comprehensive Physiology. 3: 1231-1281. PMID 23897686 DOI: 10.1002/Cphy.C120015  0.308
2013 Waheed F, Dan Q, Amoozadeh Y, Zhang Y, Tanimura S, Speight P, Kapus A, Szászi K. Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells. Molecular Biology of the Cell. 24: 1068-82. PMID 23389627 DOI: 10.1091/Mbc.E12-09-0661  0.389
2013 Ly DL, Waheed F, Lodyga M, Speight P, Masszi A, Nakano H, Hersom M, Pedersen SF, Szászi K, Kapus A. Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton. American Journal of Physiology. Cell Physiology. 304: C115-27. PMID 23054059 DOI: 10.1152/Ajpcell.00290.2012  0.415
2011 Charbonney E, Speight P, Masszi A, Nakano H, Kapus A. β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition. Molecular Biology of the Cell. 22: 4472-85. PMID 21965288 DOI: 10.1091/Mbc.E11-04-0335  0.349
2011 Pedersen SF, Kapus A, Hoffmann EK. Osmosensory mechanisms in cellular and systemic volume regulation. Journal of the American Society of Nephrology : Jasn. 22: 1587-97. PMID 21852585 DOI: 10.1681/Asn.2010121284  0.323
2011 Malam Z, Parodo J, Waheed F, Szaszi K, Kapus A, Marshall JC. Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase. Journal of Immunology (Baltimore, Md. : 1950). 186: 6474-84. PMID 21518975 DOI: 10.4049/Jimmunol.1003706  0.403
2011 Gorbatenko A, Wiwel M, Klingberg H, Nielsen AB, Kapus A, Pedersen SF. Hyperosmotic stress strongly potentiates serum response factor (SRF)-dependent transcriptional activity in Ehrlich Lettré Ascites cells through a mechanism involving p38 mitogen-activated protein kinase. Journal of Cellular Physiology. 226: 2857-68. PMID 21302281 DOI: 10.1002/Jcp.22628  0.433
2011 Masszi A, Kapus A. Smaddening complexity: the role of Smad3 in epithelial-myofibroblast transition. Cells, Tissues, Organs. 193: 41-52. PMID 21051861 DOI: 10.1159/000320180  0.354
2011 Papia G, Fan J, Kapus A, Szaszi K, Marshall JC, Tawadros P, Ailenberg M, Rotstein OD. Altered inhibitory κBα expression in LPS-stimulated alveolar macrophages following resuscitated hemorrhagic shock. Shock (Augusta, Ga.). 35: 171-7. PMID 20661182 DOI: 10.1097/Shk.0B013E3181F21D2D  0.349
2011 Kapus A, Marshall J, Jia S, Parodo J, Battisti-Charbonney E, Tsang J, Jia S, Rotstein O. Circulating Neutrophils from Trauma Patients Induce Apoptosis Through Dephosphorylation of Epithelial Cell Caspase-8 Nature Precedings. 6: 1-1. DOI: 10.1038/Npre.2011.6393.1  0.731
2010 Lodyga M, Bai XH, Kapus A, Liu M. Adaptor protein XB130 is a Rac-controlled component of lamellipodia that regulates cell motility and invasion. Journal of Cell Science. 123: 4156-69. PMID 21084565 DOI: 10.1242/Jcs.071050  0.384
2010 Xiao H, Bai XH, Kapus A, Lu WY, Mak AS, Liu M. The protein kinase C cascade regulates recruitment of matrix metalloprotease 9 to podosomes and its release and activation. Molecular and Cellular Biology. 30: 5545-61. PMID 20937775 DOI: 10.1128/Mcb.00382-10  0.369
2010 Heijink IH, Oosterhout Av, Kapus A. Epidermal growth factor receptor signalling contributes to house dust mite-induced epithelial barrier dysfunction. European Respiratory Journal. 36: 1016-1026. PMID 20351035 DOI: 10.1183/09031936.00125809  0.381
2010 Waheed F, Speight P, Kawai G, Dan Q, Kapus A, Szászi K. Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase. American Journal of Physiology. Cell Physiology. 298: C1376-87. PMID 20237148 DOI: 10.1152/Ajpcell.00408.2009  0.433
2010 Masszi A, Speight P, Charbonney E, Lodyga M, Nakano H, Szászi K, Kapus A. Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3. The Journal of Cell Biology. 188: 383-99. PMID 20123992 DOI: 10.1083/Jcb.200906155  0.336
2010 Heijink IH, Postma DS, Noordhoek JA, Broekema M, Kapus A. House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium. American Journal of Respiratory Cell and Molecular Biology. 42: 69-79. PMID 19372245 DOI: 10.1165/Rcmb.2008-0449Oc  0.32
2009 Kakiashvili E, Speight P, Waheed F, Seth R, Lodyga M, Tanimura S, Kohno M, Rotstein OD, Kapus A, Szászi K. GEF-H1 mediates tumor necrosis factor-alpha-induced Rho activation and myosin phosphorylation: role in the regulation of tubular paracellular permeability. The Journal of Biological Chemistry. 284: 11454-66. PMID 19261619 DOI: 10.1074/Jbc.M805933200  0.373
2009 Thirone AC, Speight P, Zulys M, Rotstein OD, Szászi K, Pedersen SF, Kapus A. Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response. American Journal of Physiology. Cell Physiology. 296: C463-75. PMID 19109524 DOI: 10.1152/Ajpcell.00467.2008  0.399
2009 Lodyga M, De Falco V, Bai XH, Kapus A, Melillo RM, Santoro M, Liu M. XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway. Oncogene. 28: 937-49. PMID 19060924 DOI: 10.1038/Onc.2008.447  0.371
2008 Arora PD, Conti MA, Ravid S, Sacks DB, Kapus A, Adelstein RS, Bresnick AR, McCulloch CA. Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Molecular Biology of the Cell. 19: 5032-46. PMID 18799623 DOI: 10.1091/Mbc.E08-04-0430  0.323
2008 Amin M, Magnusson KE, Kapus A, Glogauer M, Ellen RP. Treponema denticola Msp-deduced peptide conjugate, P34BSA, promotes RhoA-dependent actin stress fiber formation independent of its internalization by fibroblasts. Cell Motility and the Cytoskeleton. 65: 406-21. PMID 18330900 DOI: 10.1002/Cm.20270  0.368
2008 Sebe A, Masszi A, Zulys M, Yeung T, Speight P, Rotstein OD, Nakano H, Mucsi I, Szászi K, Kapus A. Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor. Febs Letters. 582: 291-8. PMID 18154735 DOI: 10.1016/J.Febslet.2007.12.021  0.402
2008 Jia SH, Parodo J, Kapus A, Rotstein OD, Marshall JC. Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8. The Journal of Biological Chemistry. 283: 5402-13. PMID 18086677 DOI: 10.1074/Jbc.M706462200  0.434
2008 Rasmussen M, Alexander RT, Darborg BV, Møbjerg N, Hoffmann EK, Kapus A, Pedersen SF. Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications. American Journal of Physiology. Cell Physiology. 294: C197-212. PMID 17977945 DOI: 10.1152/ajpcell.00268.2007  0.369
2008 Tawadros PS, Jung JJ, Birch SE, Kapus A, Szaszi K, Rotstein OD. QS377. Oxidant-Induced Activation of ERK in RAW 264.7 Macrophages Is Mediated by Sphingosine-1-Phosphate Journal of Surgical Research. 144: 417. DOI: 10.1016/J.Jss.2007.12.631  0.389
2008 Birch SE, Campbell M, Tawadros P, Szaszi K, Kapus A, Rotstein OD. QS375. The Role of p38 in Fer Kinase Dependent Regulation of the Jak/STAT Pathway Journal of Surgical Research. 144: 416-417. DOI: 10.1016/J.Jss.2007.12.629  0.363
2007 Tawadros PS, Powers KA, Yang I, Becker DA, Ginsberg MD, Szaszi K, Kapus A, Rotstein OD. Stilbazulenyl nitrone decreases oxidative stress and reduces lung injury after hemorrhagic shock/resuscitation and LPS. Antioxidants & Redox Signaling. 9: 1971-7. PMID 17715998 DOI: 10.1089/Ars.2007.1765  0.328
2007 Amin M, Grove DA, Kapus A, Glogauer M, Ellen RP. An actin-stabilizing peptide conjugate deduced from the major outer sheath protein of the bacterium Treponema denticola. Cell Motility and the Cytoskeleton. 64: 662-74. PMID 17565753 DOI: 10.1002/Cm.20213  0.324
2007 Zhao XH, Laschinger C, Arora P, Szászi K, Kapus A, McCulloch CA. Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway. Journal of Cell Science. 120: 1801-9. PMID 17456553 DOI: 10.1242/Jcs.001586  0.391
2007 Fan L, Sebe A, Péterfi Z, Masszi A, Thirone AC, Rotstein OD, Nakano H, McCulloch CA, Szászi K, Mucsi I, Kapus A. Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway. Molecular Biology of the Cell. 18: 1083-97. PMID 17215519 DOI: 10.1091/Mbc.E06-07-0602  0.422
2007 Hyduk SJ, Chan JR, Duffy ST, Chen M, Peterson MD, Waddell TK, Digby GC, Szaszi K, Kapus A, Cybulsky MI. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 109: 176-84. PMID 16960156 DOI: 10.1182/Blood-2006-01-029199  0.393
2007 Di Ciano-Oliveira C, Thirone AC, Szászi K, Kapus A. Osmotic stress and the cytoskeleton: the R(h)ole of Rho GTPases. Acta Physiologica (Oxford, England). 187: 257-72. PMID 16734763 DOI: 10.1111/J.1748-1716.2006.01535.X  0.344
2007 Tawadros P, Wang Z, Birch S, Szaszi K, Kapus A, Marshall J, Rotstein O. Oxidant-induced TLR4 translocation in murine macrophages is Src kinase dependent Critical Care. 11: P44. DOI: 10.1186/Cc6023  0.388
2006 Cosen-Binker LI, Kapus A. Cortactin: the gray eminence of the cytoskeleton. Physiology (Bethesda, Md.). 21: 352-61. PMID 16990456 DOI: 10.1152/Physiol.00012.2006  0.351
2006 Powers KA, Szászi K, Khadaroo RG, Tawadros PS, Marshall JC, Kapus A, Rotstein OD. Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages. The Journal of Experimental Medicine. 203: 1951-61. PMID 16847070 DOI: 10.1084/Jem.20060943  0.352
2006 Birch SE, Tawadros P, Szaszi K, Kapus A, Rotstein OD. Fer kinase is a novel regulator of Jak/STAT signaling pathway Journal of the American College of Surgeons. 203: S27-S28. DOI: 10.1016/J.Jamcollsurg.2006.05.067  0.341
2006 Tawadros PS, Birch SE, Zou M, Szaszi K, Kapus A, Rotstein OD. Oxidant-induced Akt phosphorylation in murine macrophages involves ceramide generation through the acid sphingomyelinase pathway Journal of the American College of Surgeons. 203: S26. DOI: 10.1016/J.Jamcollsurg.2006.05.063  0.395
2005 El Sayegh TY, Arora PD, Fan L, Laschinger CA, Greer PA, McCulloch CA, Kapus A. Phosphorylation of N-cadherin-associated cortactin by Fer kinase regulates N-cadherin mobility and intercellular adhesion strength. Molecular Biology of the Cell. 16: 5514-27. PMID 16176974 DOI: 10.1091/Mbc.E05-05-0410  0.385
2005 Szászi K, Sirokmány G, Di Ciano-Oliveira C, Rotstein OD, Kapus A. Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells. American Journal of Physiology. Cell Physiology. 289: C673-85. PMID 15857905 DOI: 10.1152/Ajpcell.00481.2004  0.437
2005 Szászi K, Jones JJ, Nathens AB, Lo AY, Marsden PA, Kapus A, Rotstein OD. Glutathione depletion inhibits lipopolysaccharide-induced intercellular adhesion molecule 1 synthesis. Free Radical Biology & Medicine. 38: 1333-43. PMID 15855051 DOI: 10.1016/J.Freeradbiomed.2005.01.013  0.405
2005 Di Ciano-Oliveira C, Lodyga M, Fan L, Szászi K, Hosoya H, Rotstein OD, Kapus A. Is myosin light-chain phosphorylation a regulatory signal for the osmotic activation of the Na+-K+-2Cl- cotransporter? American Journal of Physiology. Cell Physiology. 289: C68-81. PMID 15728707 DOI: 10.1152/Ajpcell.00631.2004  0.426
2005 Wang Q, Downey GP, Bajenova E, Abreu M, Kapus A, McCulloch CA. Mitochondrial function is a critical determinant of IL-1-induced ERK activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 837-9. PMID 15728661 DOI: 10.1096/Fj.04-2657Fje  0.309
2005 Peterson MD, Vlasova E, Di Ciano-Oliveira C, Downey GP, Cybulsky MI, Kapus A, Waddell TK. Monocyte-induced endothelial calcium signaling mediates early xenogeneic endothelial activation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 237-47. PMID 15643983 DOI: 10.1111/J.1600-6143.2004.00666.X  0.336
2005 Powers KA, Zurawska J, Szaszi K, Khadaroo RG, Kapus A, Rotstein OD. Hypertonic resuscitation of hemorrhagic shock prevents alveolar macrophage activation by preventing systemic oxidative stress due to gut ischemia/reperfusion. Surgery. 137: 66-74. PMID 15614283 DOI: 10.1016/J.Surg.2004.05.051  0.337
2005 Wang J, Fan J, Laschinger C, Arora PD, Kapus A, Seth A, McCulloch CA. Smooth muscle actin determines mechanical force-induced p38 activation. The Journal of Biological Chemistry. 280: 7273-84. PMID 15591055 DOI: 10.1074/Jbc.M410819200  0.365
2005 Wang Q, Downey GP, Herrera-Abreu MT, Kapus A, McCulloch CA. SHP-2 modulates interleukin-1-induced Ca2+ flux and ERK activation via phosphorylation of phospholipase Cgamma1. The Journal of Biological Chemistry. 280: 8397-406. PMID 15563458 DOI: 10.1074/Jbc.M410462200  0.339
2005 Powers KA, Szaszi K, Khadaroo R, Tawadros P, Marshall JC, Kapus A, Rotstein OD. Hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages: A novel mechanism of cell priming for LPS signaling Journal of the American College of Surgeons. 201: S36. DOI: 10.1016/J.Jamcollsurg.2005.06.070  0.324
2004 El Sayegh TY, Arora PD, Laschinger CA, Lee W, Morrison C, Overall CM, Kapus A, McCulloch CA. Cortactin associates with N-cadherin adhesions and mediates intercellular adhesion strengthening in fibroblasts. Journal of Cell Science. 117: 5117-31. PMID 15383621 DOI: 10.1242/Jcs.01385  0.323
2004 Khadaroo RG, Fan J, Powers KA, Fann B, Kapus A, Rotstein OD. Impaired induction of IL-10 expression in the lung following hemorrhagic shock. Shock (Augusta, Ga.). 22: 333-9. PMID 15377888 DOI: 10.1097/01.Shk.0000136095.96306.08  0.301
2004 Khadaroo RG, He R, Parodo J, Powers KA, Marshall JC, Kapus A, Rotstein OD. The role of the Src family of tyrosine kinases after oxidant-induced lung injury in vivo. Surgery. 136: 483-8. PMID 15300219 DOI: 10.1016/J.Surg.2004.05.029  0.387
2004 Taneja R, Parodo J, Jia SH, Kapus A, Rotstein OD, Marshall JC. Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity. Critical Care Medicine. 32: 1460-9. PMID 15241089 DOI: 10.1097/01.Ccm.0000129975.26905.77  0.38
2004 Jia SH, Li Y, Parodo J, Kapus A, Fan L, Rotstein OD, Marshall JC. Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. The Journal of Clinical Investigation. 113: 1318-27. PMID 15124023 DOI: 10.1172/Jci19930  0.391
2004 Fan L, Di Ciano-Oliveira C, Weed SA, Craig AW, Greer PA, Rotstein OD, Kapus A. Actin depolymerization-induced tyrosine phosphorylation of cortactin: the role of Fer kinase. The Biochemical Journal. 380: 581-91. PMID 15030313 DOI: 10.1042/Bj20040178  0.361
2004 Arora PD, Glogauer M, Kapus A, Kwiatkowski DJ, McCulloch CA. Gelsolin mediates collagen phagocytosis through a rac-dependent step. Molecular Biology of the Cell. 15: 588-99. PMID 14617805 DOI: 10.1091/Mbc.E03-07-0468  0.353
2004 JeBailey L, Rudich A, Huang X, Di Ciano-Oliveira C, Kapus A, Klip A. Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling. Molecular Endocrinology (Baltimore, Md.). 18: 359-72. PMID 14615606 DOI: 10.1210/Me.2003-0294  0.327
2004 Khadaroo RG, Parodo J, Powers KA, Marshall JC, Kapus A, Rotstein OD. OXIDANT-INDUCED PRIMING OF THE MACROPHAGE INVOLVES TYROSINE PHOSPHORYLATION OF IKK VIA A SRC KINASE PATHWAY Shock. 21: 41. DOI: 10.1097/00024382-200403001-00164  0.386
2004 Powers KA, Szaszi K, Khadaroo RG, Papia G, Kapus A, Rotstein OD. LIPID RAFT RECRUITMENT OF TOLL LIKE RECEPTOR-4 (TLR4) IS NECESSARY FOR OXIDANAT INDUCED NFKAPPAB TRANSLOCATION IN MACROPHAGES. Shock. 21: 20. DOI: 10.1097/00024382-200403001-00078  0.302
2004 Powers KA, Fan B, Szaszi K, Khadaroo RG, Kapus A, Rotstein OD. Stilbazulenyl nitrone (STAZN), a novel azulenyl nitrone antioxidant prevents lung injury following hemorrhagic shock and alters TLR4 distribution in alveolar macrophages Journal of the American College of Surgeons. 199: 40. DOI: 10.1016/J.Jamcollsurg.2004.05.073  0.356
2003 Powers KA, Woo J, Khadaroo RG, Papia G, Kapus A, Rotstein OD. Hypertonic resuscitation of hemorrhagic shock upregulates the anti-inflammatory response by alveolar macrophages. Surgery. 134: 312-8. PMID 12947335 DOI: 10.1067/Msy.2003.246  0.31
2003 Khadaroo RG, Parodo J, Powers KA, Papia G, Marshall JC, Kapus A, Rotstein OD. Oxidant-induced priming of the macrophage involves activation of p38 mitogen-activated protein kinase through an Src-dependent pathway. Surgery. 134: 242-6. PMID 12947324 DOI: 10.1067/Msy.2003.228  0.434
2003 Khadaroo RG, Kapus A, Powers KA, Cybulsky MI, Marshall JC, Rotstein OD. Oxidative stress reprograms lipopolysaccharide signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. The Journal of Biological Chemistry. 278: 47834-41. PMID 12896983 DOI: 10.1074/Jbc.M302660200  0.391
2003 Di Ciano-Oliveira C, Sirokmány G, Szászi K, Arthur WT, Masszi A, Peterson M, Rotstein OD, Kapus A. Hyperosmotic stress activates Rho: differential involvement in Rho kinase-dependent MLC phosphorylation and NKCC activation. American Journal of Physiology. Cell Physiology. 285: C555-66. PMID 12748065 DOI: 10.1152/Ajpcell.00086.2003  0.426
2003 Masszi A, Di Ciano C, Sirokmány G, Arthur WT, Rotstein OD, Wang J, McCulloch CA, Rosivall L, Mucsi I, Kapus A. Central role for Rho in TGF-beta1-induced alpha-smooth muscle actin expression during epithelial-mesenchymal transition. American Journal of Physiology. Renal Physiology. 284: F911-24. PMID 12505862 DOI: 10.1152/Ajprenal.00183.2002  0.365
2002 Powers KA, Kapus A, Khadaroo RG, Papia G, Rotstein OD. 25% Albumin modulates adhesive interactions between neutrophils and the endothelium following shock/resuscitation. Surgery. 132: 391-8. PMID 12219040 DOI: 10.1067/Msy.2002.126508  0.315
2002 Di Ciano C, Nie Z, Szászi K, Lewis A, Uruno T, Zhan X, Rotstein OD, Mak A, Kapus A. Osmotic stress-induced remodeling of the cortical cytoskeleton. American Journal of Physiology. Cell Physiology. 283: C850-65. PMID 12176742 DOI: 10.1152/Ajpcell.00018.2002  0.406
2002 Fan J, Kapus A, Marsden PA, Li YH, Oreopoulos G, Marshall JC, Frantz S, Kelly RA, Medzhitov R, Rotstein OD. Regulation of Toll-like receptor 4 expression in the lung following hemorrhagic shock and lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 168: 5252-9. PMID 11994482 DOI: 10.4049/Jimmunol.168.10.5252  0.31
2002 Lewis A, Di Ciano C, Rotstein OD, Kapus A. Osmotic stress activates Rac and Cdc42 in neutrophils: role in hypertonicity-induced actin polymerization. American Journal of Physiology. Cell Physiology. 282: C271-9. PMID 11788338 DOI: 10.1152/Ajpcell.00427.2001  0.433
2001 Aharonovitz O, Kapus A, Szászi K, Coady-Osberg N, Jancelewicz T, Orlowski J, Grinstein S. Modulation of Na+/H+ exchange activity by Cl- American Journal of Physiology - Cell Physiology. 281. PMID 11401835 DOI: 10.1152/Ajpcell.2001.281.1.C133  0.328
2000 Szászi K, Grinstein S, Orlowski J, Kapus A. Regulation of the epithelial Na+/H+ exchanger isoform by the cytoskeleton Cellular Physiology and Biochemistry. 10: 265-272. PMID 11125205 DOI: 10.1159/000016358  0.377
2000 McGilvray ID, Serghides L, Kapus A, Rotstein OD, Kain KC. Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum-parasitized erythrocytes: a role for CD36 in malarial clearance. Blood. 96: 3231-40. PMID 11050008 DOI: 10.1182/Blood.V96.9.3231.H8003231_3231_3240  0.338
2000 Oreopoulos GD, Hamilton J, Rizoli SB, Fan J, Lu Z, Li YH, Marshall JC, Kapus A, Rotstein OD. In vivo and in vitro modulation of intercellular adhesion molecule (ICAM)-1 expression by hypertonicity. Shock (Augusta, Ga.). 14: 409-14; discussion 4. PMID 11028565 DOI: 10.1097/00024382-200014030-00029  0.327
2000 Rizoli SB, Rotstein OD, Parodo J, Phillips MJ, Kapus A. Hypertonic inhibition of exocytosis in neutrophils: central role for osmotic actin skeleton remodeling. American Journal of Physiology. Cell Physiology. 279: C619-33. PMID 10942712 DOI: 10.1152/Ajpcell.2000.279.3.C619  0.408
2000 Fan J, Kapus A, Li YH, Rizoli S, Marshall JC, Rotstein OD. Priming for enhanced alveolar fibrin deposition after hemorrhagic shock: role of tumor necrosis factor. American Journal of Respiratory Cell and Molecular Biology. 22: 412-21. PMID 10745022 DOI: 10.1165/Ajrcmb.22.4.3857  0.352
2000 Kapus A, Sun J, Szászi K, DiCiano C, Wong T, Mak A, Rotstein O. Cell volume-dependent phosphorylation and reorganization of elements of the cortical cytoskeleton and the cell-cell contacts Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 126: 75. DOI: 10.1016/S1095-6433(00)80148-8  0.331
1999 Jones JJ, Fan J, Nathens AB, Kapus A, Shekhman M, Marshall JC, Parodo J, Rotstein OD. Redox manipulation using the thiol-oxidizing agent diethyl maleate prevents hepatocellular necrosis and apoptosis in a rodent endotoxemia model. Hepatology (Baltimore, Md.). 30: 714-24. PMID 10462378 DOI: 10.1002/Hep.510300324  0.392
1999 Rizoli SB, Rotstein OD, Kapus A. Cell volume-dependent regulation of L-selectin shedding in neutrophils. A role for p38 mitogen-activated protein kinase. The Journal of Biological Chemistry. 274: 22072-80. PMID 10419535 DOI: 10.1074/Jbc.274.31.22072  0.429
1999 Rizoli SB, Kapus A, Parodo J, Rotstein OD. Hypertonicity prevents lipopolysaccharide-stimulated CD11b/CD18 expression in human neutrophils in vitro: role for p38 inhibition. The Journal of Trauma. 46: 794-8; discussion 79. PMID 10338395 DOI: 10.1097/00005373-199905000-00006  0.346
1999 Kapus A, Szászi K, Sun J, Rizoli S, Rotstein OD. Cell shrinkage regulates Src kinases and induces tyrosine phosphorylation of cortactin, independent of the osmotic regulation of Na+/H+ exchangers. The Journal of Biological Chemistry. 274: 8093-102. PMID 10075710 DOI: 10.1074/Jbc.274.12.8093  0.421
1999 Rizoli S, Rotstein O, Kapus A. Hypertonicity induces shedding of L-selectin: a role for p38 activation Critical Care. 3: P087. DOI: 10.1186/Cc461  0.405
1998 McGilvray ID, Lu Z, Wei AC, Dackiw AP, Marshall JC, Kapus A, Levy G, Rotstein OD. Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation. The Journal of Biological Chemistry. 273: 32222-9. PMID 9822700 DOI: 10.1074/Jbc.273.48.32222  0.418
1998 Rizoli S, Kapus A, Rotstein O. HYPERIONICITY INHIBITS THE ACTIVATION OF p38 MAPK IN NEUIROPHILS The Journal of Trauma: Injury, Infection, and Critical Care. 45: 201. DOI: 10.1097/00005373-199807000-00092  0.32
1997 Geiszt M, Kapus A, Német K, Farkas L, Ligeti E. Regulation of capacitative Ca2+ influx in human neutrophil granulocytes. Alterations in chronic granulomatous disease. The Journal of Biological Chemistry. 272: 26471-8. PMID 9334224 DOI: 10.1074/Jbc.272.42.26471  0.328
1996 Cabado AG, Yu FH, Kapus A, Lukacs G, Grinstein S, Orlowski J. Distinct structural domains confer cAMP sensitivity and ATP dependence to the Na+/H+ exchanger NHE3 isoform. The Journal of Biological Chemistry. 271: 3590-9. PMID 8631966 DOI: 10.1074/Jbc.271.7.3590  0.342
1993 Lukacs GL, Kapus A, Nanda A, Romanek R, Grinstein S. Proton conductance of the plasma membrane: properties, regulation, and functional role. The American Journal of Physiology. 265: C3-14. PMID 8393283 DOI: 10.1152/Ajpcell.1993.265.1.C3  0.303
1993 Kapus A, Romanek R, Qu AY, Rotstein OD, Grinstein S. A pH-sensitive and voltage-dependent proton conductance in the plasma membrane of macrophages Journal of General Physiology. 102: 729-760. PMID 8270911 DOI: 10.1085/Jgp.102.4.729  0.307
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