| Year |
Citation |
Score |
| 2022 |
Carranza F, Shenasa H, Hertel KJ. Splice site proximity influences alternative exon definition. Rna Biology. 19: 829-840. PMID 35723015 DOI: 10.1080/15476286.2022.2089478 |
0.575 |
|
| 2021 |
Altieri JAC, Hertel KJ. The influence of 4-thiouridine labeling on pre-mRNA splicing outcomes. Plos One. 16: e0257503. PMID 34898625 DOI: 10.1371/journal.pone.0257503 |
0.506 |
|
| 2020 |
Shenasa H, Movassat M, Forouzmand EJ, Hertel KJ. Allosteric Regulation of U1 snRNP by Splicing Regulatory Proteins Controls Spliceosomal Assembly. Rna (New York, N.Y.). PMID 32522889 DOI: 10.1261/Rna.075135.120 |
0.593 |
|
| 2019 |
Reynolds DJ, Hertel KJ. Ultra-deep sequencing reveals pre-mRNA splicing as a sequence driven high-fidelity process. Plos One. 14: e0223132. PMID 31581208 DOI: 10.1371/Journal.Pone.0223132 |
0.648 |
|
| 2019 |
Movassat M, Forouzmand E, Reese F, Hertel KJ. Exon Size and Sequence Conservation Improves Identification of Splice Altering Nucleotides. Rna (New York, N.Y.). PMID 31554659 DOI: 10.1261/Rna.070987.119 |
0.482 |
|
| 2019 |
Shenasa H, Hertel KJ. Combinatorial regulation of alternative splicing. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. PMID 31276857 DOI: 10.1016/J.Bbagrm.2019.06.003 |
0.633 |
|
| 2018 |
Zhu Y, Wang X, Forouzmand E, Jeong J, Qiao F, Sowd GA, Engelman AN, Xie X, Hertel KJ, Shi Y. Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation. Molecular Cell. 69: 62-74.e4. PMID 29276085 DOI: 10.1016/J.Molcel.2017.11.031 |
0.547 |
|
| 2017 |
Garibaldi A, Carranza F, Hertel KJ. Isolation of Newly Transcribed RNA Using the Metabolic Label 4-Thiouridine. Methods in Molecular Biology (Clifton, N.J.). 1648: 169-176. PMID 28766297 DOI: 10.1007/978-1-4939-7204-3_13 |
0.42 |
|
| 2017 |
Movassat M, Shenasa H, Hertel KJ. Preparation of Splicing Competent Nuclear Extract from Mammalian Cells and In Vitro Pre-mRNA Splicing Assay. Methods in Molecular Biology (Clifton, N.J.). 1648: 11-26. PMID 28766286 DOI: 10.1007/978-1-4939-7204-3_2 |
0.504 |
|
| 2016 |
Aubol BE, Wu G, Keshwani MM, Movassat M, Fattet L, Hertel KJ, Fu XD, Adams JA. Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Molecular Cell. PMID 27397683 DOI: 10.1016/J.Molcel.2016.05.034 |
0.408 |
|
| 2016 |
Movassat M, Crabb TL, Busch A, Yao C, Reynolds DJ, Shi Y, Hertel KJ. Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns. Rna Biology. 0. PMID 27245359 DOI: 10.1080/15476286.2016.1191727 |
0.809 |
|
| 2015 |
Mueller WF, Larsen LS, Garibaldi A, Hatfield GW, Hertel KJ. The Silent Sway of Splicing by Synonymous Substitutions. The Journal of Biological Chemistry. PMID 26424794 DOI: 10.1074/Jbc.M115.684035 |
0.556 |
|
| 2015 |
Busch A, Hertel KJ. Splicing predictions reliably classify different types of alternative splicing. Rna (New York, N.Y.). 21: 813-23. PMID 25805853 DOI: 10.1261/Rna.048769.114 |
0.644 |
|
| 2014 |
Hoverter NP, Zeller MD, McQuade MM, Garibaldi A, Busch A, Selwan EM, Hertel KJ, Baldi P, Waterman ML. The TCF C-clamp DNA binding domain expands the Wnt transcriptome via alternative target recognition. Nucleic Acids Research. 42: 13615-32. PMID 25414359 DOI: 10.1093/Nar/Gku1186 |
0.432 |
|
| 2014 |
von Figura G, Fukuda A, Roy N, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J, Mueller WF, Busch A, Hertel KJ, Hebrok M. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. Nature Cell Biology. 16: 255-67. PMID 24561622 DOI: 10.1038/Ncb2916 |
0.323 |
|
| 2014 |
Mueller WF, Hertel KJ. Kinetic analysis of in vitro pre-mRNA splicing in HeLa nuclear extract. Methods in Molecular Biology (Clifton, N.J.). 1126: 161-8. PMID 24549663 DOI: 10.1007/978-1-62703-980-2_12 |
0.496 |
|
| 2014 |
Movassat M, Mueller WF, Hertel KJ. In vitro assay of pre-mRNA splicing in mammalian nuclear extract. Methods in Molecular Biology (Clifton, N.J.). 1126: 151-60. PMID 24549662 DOI: 10.1007/978-1-62703-980-2_11 |
0.494 |
|
| 2014 |
Webb CH, Hertel KJ. Preparation of splicing competent nuclear extracts. Methods in Molecular Biology (Clifton, N.J.). 1126: 117-21. PMID 24549659 DOI: 10.1007/978-1-62703-980-2_8 |
0.356 |
|
| 2013 |
Erkelenz S, Mueller WF, Evans MS, Busch A, Schöneweis K, Hertel KJ, Schaal H. Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms. Rna (New York, N.Y.). 19: 96-102. PMID 23175589 DOI: 10.1261/Rna.037044.112 |
0.619 |
|
| 2013 |
Busch A, Hertel KJ. HEXEvent: a database of Human EXon splicing Events. Nucleic Acids Research. 41: D118-24. PMID 23118488 DOI: 10.1093/Nar/Gks969 |
0.393 |
|
| 2012 |
Busch A, Hertel KJ. Extensive regulation of NAGNAG alternative splicing: new tricks for the spliceosome? Genome Biology. 13: 143. PMID 22356731 DOI: 10.1186/Gb3999 |
0.442 |
|
| 2012 |
Busch A, Hertel KJ. Evolution of SR protein and hnRNP splicing regulatory factors. Wiley Interdisciplinary Reviews. Rna. 3: 1-12. PMID 21898828 DOI: 10.1002/Wrna.100 |
0.637 |
|
| 2011 |
Shepard PJ, Choi EA, Busch A, Hertel KJ. Efficient internal exon recognition depends on near equal contributions from the 3' and 5' splice sites. Nucleic Acids Research. 39: 8928-37. PMID 21795381 DOI: 10.1093/Nar/Gkr481 |
0.634 |
|
| 2011 |
Shepard PJ, Choi EA, Lu J, Flanagan LA, Hertel KJ, Shi Y. Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq. Rna (New York, N.Y.). 17: 761-72. PMID 21343387 DOI: 10.1261/Rna.2581711 |
0.545 |
|
| 2011 |
Han J, Ding JH, Byeon CW, Kim JH, Hertel KJ, Jeong S, Fu XD. SR proteins induce alternative exon skipping through their activities on the flanking constitutive exons. Molecular and Cellular Biology. 31: 793-802. PMID 21135118 DOI: 10.1128/Mcb.01117-10 |
0.407 |
|
| 2011 |
Wang E, Mueller WF, Hertel KJ, Cambi F. G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site. The Journal of Biological Chemistry. 286: 4059-71. PMID 21127064 DOI: 10.1074/Jbc.M110.199927 |
0.586 |
|
| 2010 |
Crabb TL, Lam BJ, Hertel KJ. Retention of spliceosomal components along ligated exons ensures efficient removal of multiple introns. Rna (New York, N.Y.). 16: 1786-96. PMID 20610656 DOI: 10.1261/Rna.2186510 |
0.777 |
|
| 2010 |
Shepard PJ, Hertel KJ. Embracing the complexity of pre-mRNA splicing. Cell Research. 20: 866-8. PMID 20603640 DOI: 10.1038/Cr.2010.98 |
0.647 |
|
| 2010 |
Hicks MJ, Mueller WF, Shepard PJ, Hertel KJ. Competing upstream 5' splice sites enhance the rate of proximal splicing. Molecular and Cellular Biology. 30: 1878-86. PMID 20123971 DOI: 10.1128/Mcb.01071-09 |
0.624 |
|
| 2009 |
Geib T, Hertel KJ. Restoration of full-length SMN promoted by adenoviral vectors expressing RNA antisense oligonucleotides embedded in U7 snRNAs. Plos One. 4: e8204. PMID 19997596 DOI: 10.1371/Journal.Pone.0008204 |
0.414 |
|
| 2009 |
Tannukit S, Crabb TL, Hertel KJ, Wen X, Jans DA, Paine ML. Identification of a novel nuclear localization signal and speckle-targeting sequence of tuftelin-interacting protein 11, a splicing factor involved in spliceosome disassembly. Biochemical and Biophysical Research Communications. 390: 1044-50. PMID 19857462 DOI: 10.1016/J.Bbrc.2009.10.111 |
0.752 |
|
| 2009 |
Shepard PJ, Hertel KJ. The SR protein family. Genome Biology. 10: 242. PMID 19857271 DOI: 10.1186/Gb-2009-10-10-242 |
0.526 |
|
| 2009 |
Hsu SN, Hertel KJ. Spliceosomes walk the line: splicing errors and their impact on cellular function. Rna Biology. 6: 526-30. PMID 19829058 DOI: 10.4161/Rna.6.5.9860 |
0.564 |
|
| 2009 |
Klaue Y, Hertel KJ. Dangerous play--splitting the message may leave you empty handed. Nature Structural & Molecular Biology. 16: 907-8. PMID 19739289 DOI: 10.1038/Nsmb0909-907 |
0.552 |
|
| 2009 |
Fox-Walsh KL, Hertel KJ. Splice-site pairing is an intrinsically high fidelity process. Proceedings of the National Academy of Sciences of the United States of America. 106: 1766-71. PMID 19179398 DOI: 10.1073/Pnas.0813128106 |
0.665 |
|
| 2009 |
Kotlajich MV, Crabb TL, Hertel KJ. Spliceosome assembly pathways for different types of alternative splicing converge during commitment to splice site pairing in the A complex. Molecular and Cellular Biology. 29: 1072-82. PMID 19064642 DOI: 10.1128/Mcb.01071-08 |
0.779 |
|
| 2008 |
Kotlajich MV, Hertel KJ. Death by splicing: tumor suppressor RBM5 freezes splice-site pairing. Molecular Cell. 32: 162-4. PMID 18951082 DOI: 10.1016/J.Molcel.2008.10.008 |
0.808 |
|
| 2008 |
Shepard PJ, Hertel KJ. Conserved RNA secondary structures promote alternative splicing. Rna (New York, N.Y.). 14: 1463-9. PMID 18579871 DOI: 10.1261/Rna.1069408 |
0.648 |
|
| 2008 |
Hertel KJ. Combinatorial control of exon recognition. The Journal of Biological Chemistry. 283: 1211-5. PMID 18024426 DOI: 10.1074/Jbc.R700035200 |
0.681 |
|
| 2006 |
Sciabica KS, Hertel KJ. The splicing regulators Tra and Tra2 are unusually potent activators of pre-mRNA splicing. Nucleic Acids Research. 34: 6612-20. PMID 17135210 DOI: 10.1093/Nar/Gkl984 |
0.466 |
|
| 2006 |
Dou Y, Fox-Walsh KL, Baldi PF, Hertel KJ. Genomic splice-site analysis reveals frequent alternative splicing close to the dominant splice site. Rna (New York, N.Y.). 12: 2047-56. PMID 17053087 DOI: 10.1261/Rna.151106 |
0.661 |
|
| 2006 |
Hicks MJ, Yang CR, Kotlajich MV, Hertel KJ. Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns. Plos Biology. 4: e147. PMID 16640457 DOI: 10.1371/Journal.Pbio.0040147 |
0.832 |
|
| 2005 |
Hicks MJ, Lam BJ, Hertel KJ. Analyzing mechanisms of alternative pre-mRNA splicing using in vitro splicing assays. Methods (San Diego, Calif.). 37: 306-13. PMID 16314259 DOI: 10.1016/J.Ymeth.2005.07.012 |
0.841 |
|
| 2005 |
Fox-Walsh KL, Dou Y, Lam BJ, Hung SP, Baldi PF, Hertel KJ. The architecture of pre-mRNAs affects mechanisms of splice-site pairing. Proceedings of the National Academy of Sciences of the United States of America. 102: 16176-81. PMID 16260721 DOI: 10.1073/Pnas.0508489102 |
0.852 |
|
| 2005 |
Madocsai C, Lim SR, Geib T, Lam BJ, Hertel KJ. Correction of SMN2 Pre-mRNA splicing by antisense U7 small nuclear RNAs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 1013-22. PMID 16226920 DOI: 10.1016/J.Ymthe.2005.08.022 |
0.782 |
|
| 2005 |
Freund M, Hicks MJ, Konermann C, Otte M, Hertel KJ, Schaal H. Extended base pair complementarity between U1 snRNA and the 5' splice site does not inhibit splicing in higher eukaryotes, but rather increases 5' splice site recognition. Nucleic Acids Research. 33: 5112-9. PMID 16155183 DOI: 10.1093/Nar/Gki824 |
0.637 |
|
| 2005 |
Ibrahim EC, Schaal TD, Hertel KJ, Reed R, Maniatis T. Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. Proceedings of the National Academy of Sciences of the United States of America. 102: 5002-7. PMID 15753297 DOI: 10.1073/Pnas.0500543102 |
0.636 |
|
| 2005 |
Hertel KJ, Graveley BR. RS domains contact the pre-mRNA throughout spliceosome assembly. Trends in Biochemical Sciences. 30: 115-8. PMID 15752982 DOI: 10.1016/J.Tibs.2005.01.002 |
0.399 |
|
| 2004 |
Lim SR, Hertel KJ. Commitment to splice site pairing coincides with A complex formation. Molecular Cell. 15: 477-83. PMID 15304226 DOI: 10.1016/J.Molcel.2004.06.025 |
0.846 |
|
| 2003 |
Lam BJ, Bakshi A, Ekinci FY, Webb J, Graveley BR, Hertel KJ. Enhancer-dependent 5'-splice site control of fruitless pre-mRNA splicing. The Journal of Biological Chemistry. 278: 22740-7. PMID 12646561 DOI: 10.1074/Jbc.M301036200 |
0.844 |
|
| 2002 |
Lam BJ, Hertel KJ. A general role for splicing enhancers in exon definition. Rna (New York, N.Y.). 8: 1233-41. PMID 12403462 DOI: 10.1017/S1355838202028030 |
0.847 |
|
| 2001 |
Lim SR, Hertel KJ. Modulation of survival motor neuron pre-mRNA splicing by inhibition of alternative 3' splice site pairing. The Journal of Biological Chemistry. 276: 45476-83. PMID 11584013 DOI: 10.1074/Jbc.M107632200 |
0.846 |
|
| 2001 |
Graveley BR, Hertel KJ, Maniatis T. The role of U2AF35 and U2AF65 in enhancer-dependent splicing. Rna (New York, N.Y.). 7: 806-18. PMID 11421359 DOI: 10.1017/S1355838201010317 |
0.615 |
|
| 1999 |
Hertel KJ, Maniatis T. Serine-arginine (SR)-rich splicing factors have an exon-independent function in pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America. 96: 2651-5. PMID 10077565 DOI: 10.1073/Pnas.96.6.2651 |
0.563 |
|
| 1998 |
Hertel KJ, Stage-Zimmermann TK, Ammons G, Uhlenbeck OC. Thermodynamic dissection of the substrate-ribozyme interaction in the hammerhead ribozyme. Biochemistry. 37: 16983-8. PMID 9836592 DOI: 10.1021/Bi981740B |
0.311 |
|
| 1998 |
Graveley BR, Hertel KJ, Maniatis T. A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers. The Embo Journal. 17: 6747-56. PMID 9822617 DOI: 10.1093/Emboj/17.22.6747 |
0.557 |
|
| 1998 |
Hertel KJ, Maniatis T. The function of multisite splicing enhancers. Molecular Cell. 1: 449-55. PMID 9660929 DOI: 10.1016/S1097-2765(00)80045-3 |
0.509 |
|
| 1997 |
Hertel KJ, Peracchi A, Uhlenbeck OC, Herschlag D. Use of intrinsic binding energy for catalysis by an RNA enzyme. Proceedings of the National Academy of Sciences of the United States of America. 94: 8497-502. PMID 9238005 DOI: 10.1073/Pnas.94.16.8497 |
0.342 |
|
| 1997 |
Hertel KJ, Lynch KW, Maniatis T. Common themes in the function of transcription and splicing enhancers. Current Opinion in Cell Biology. 9: 350-7. PMID 9159075 DOI: 10.1016/S0955-0674(97)80007-5 |
0.581 |
|
| 1996 |
Hertel KJ, Herschlag D, Uhlenbeck OC. Specificity of hammerhead ribozyme cleavage. The Embo Journal. 15: 3751-7. PMID 8670879 |
0.308 |
|
| 1996 |
Hertel KJ, Herschlag D, Uhlenbeck OC. Specificity of hammerhead ribozyme cleavage. The Embo Journal. 15: 3751-3757. DOI: 10.1002/J.1460-2075.1996.Tb00745.X |
0.425 |
|
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