| Year |
Citation |
Score |
| 2023 |
Minns MS, Liboro K, Lima TS, Abbondante S, Miller BA, Marshall ME, Tran Chau J, Roistacher A, Rietsch A, Dubyak GR, Pearlman E. NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity. Nature Communications. 14: 5832. PMID 37730693 DOI: 10.1038/s41467-023-41391-7 |
0.372 |
|
| 2023 |
Abbondante S, Leal SM, Clark HL, Ratitong B, Sun Y, Ma LJ, Pearlman E. Immunity to pathogenic fungi in the eye. Seminars in Immunology. 67: 101753. PMID 37060806 DOI: 10.1016/j.smim.2023.101753 |
0.695 |
|
| 2023 |
Dubyak GR, Miller BA, Pearlman E. Pyroptosis in neutrophils: Multimodal integration of inflammasome and regulated cell death signaling pathways. Immunological Reviews. PMID 36656082 DOI: 10.1111/imr.13186 |
0.378 |
|
| 2022 |
Ratitong B, Marshall ME, Dragan MA, Anunciado CM, Abbondante S, Pearlman E. Differential Roles for IL-1α and IL-1β in Corneal Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 35851538 DOI: 10.4049/jimmunol.2200110 |
0.376 |
|
| 2021 |
Ratitong B, Pearlman E. Pathogenic Aspergillus and Fusarium as important causes of blinding corneal infections - the role of neutrophils in fungal killing, tissue damage and cytokine production. Current Opinion in Microbiology. 63: 195-203. PMID 34419783 DOI: 10.1016/j.mib.2021.07.018 |
0.396 |
|
| 2020 |
Karmakar M, Minns M, Greenberg EN, Diaz-Aponte J, Pestonjamasp K, Johnson JL, Rathkey JK, Abbott DW, Wang K, Shao F, Catz SD, Dubyak GR, Pearlman E. N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Nature Communications. 11: 2212. PMID 32371889 DOI: 10.1038/S41467-020-16043-9 |
0.346 |
|
| 2020 |
Mouyna I, Dellière S, Beauvais A, Gravelat F, Snarr B, Lehoux M, Zacharias C, Sun Y, de Jesus Carrion S, Pearlman E, Sheppard DC, Latgé JP. What Are the Functions of Chitin Deacetylases in ? Frontiers in Cellular and Infection Microbiology. 10: 28. PMID 32117802 DOI: 10.3389/Fcimb.2020.00028 |
0.341 |
|
| 2019 |
Flesher JL, Paterson-Coleman EK, Vasudeva P, Ruiz-Vega R, Marshall M, Pearlman E, MacGregor GR, Neumann J, Ganesan AK. Delineating the Role of MITF Isoforms in Pigmentation and Tissue Homeostasis. Pigment Cell & Melanoma Research. PMID 31562697 DOI: 10.1111/Pcmr.12828 |
0.307 |
|
| 2019 |
Albin TJ, Tom JK, Manna S, Gilkes AP, Stetkevich SA, Katz BB, Supnet M, Felgner J, Jain A, Nakajima R, Jasinskas A, Zlotnik A, Pearlman E, Davies DH, Felgner PL, et al. Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses. Acs Central Science. 5: 1137-1145. PMID 31403067 DOI: 10.1021/Acscentsci.8B00823 |
0.398 |
|
| 2019 |
Coulon PG, Dhanushkodi N, Prakash S, Srivastava R, Roy S, Alomari NI, Nguyen AM, Warsi WR, Ye C, Carlos-Cruz EA, Mai UT, Cruel AC, Ekmekciyan KM, Pearlman E, BenMohamed L. NLRP3, NLRP12, and IFI16 Inflammasomes Induction and Caspase-1 Activation Triggered by Virulent HSV-1 Strains Are Associated With Severe Corneal Inflammatory Herpetic Disease. Frontiers in Immunology. 10: 1631. PMID 31367214 DOI: 10.3389/Fimmu.2019.01631 |
0.467 |
|
| 2019 |
Swidergall M, Solis NV, Wang Z, Phan QT, Marshall ME, Lionakis MS, Pearlman E, Filler SG. EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection. Cell Reports. 28: 423-433.e5. PMID 31291578 DOI: 10.1016/J.Celrep.2019.06.020 |
0.411 |
|
| 2019 |
Carrion SJ, Abbondante S, Clark HL, Marshall ME, Mouyna I, Beauvais A, Sun Y, Taylor PR, Leal SM, Armstrong B, Carrera W, Latge JP, Pearlman E. Aspergillus fumigatus corneal infection is regulated by chitin synthases and by neutrophil-derived acidic mammalian chitinase. European Journal of Immunology. PMID 30903663 DOI: 10.1002/Eji.201847851 |
0.716 |
|
| 2019 |
Carrion SdJ, Abbondante S, Clark HL, Marshall ME, Mouyna I, Beauvais A, Sun Y, Taylor PR, Leal SM, Armstrong B, Carrera W, Latge J, Pearlman E. Author response for " Aspergillus fumigatus corneal infection is regulated by chitin synthases and by neutrophil–derived acidic mammalian chitinase" European Journal of Immunology. DOI: 10.1002/Eji.201847851/V2/Response1 |
0.674 |
|
| 2018 |
Hill LJ, Moakes RJA, Vareechon C, Butt G, Ng A, Brock K, Chouhan G, Vincent RC, Abbondante S, Williams RL, Barnes NM, Pearlman E, Wallace GR, Rauz S, Logan A, et al. Sustained release of decorin to the surface of the eye enables scarless corneal regeneration. Npj Regenerative Medicine. 3: 23. PMID 30588331 DOI: 10.1038/S41536-018-0061-4 |
0.31 |
|
| 2018 |
Sun Y, Abbondante S, Karmakar M, de Jesus Carrion S, Che C, Hise AG, Pearlman E. Neutrophil Caspase-11 Is Required for Cleavage of Caspase-1 and Secretion of IL-1β in Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 30266768 DOI: 10.4049/Jimmunol.1701195 |
0.431 |
|
| 2018 |
Clark HL, Abbondante S, Minns MS, Greenberg EN, Sun Y, Pearlman E. Protein Deiminase 4 and CR3 Regulate and β-Glucan-Induced Neutrophil Extracellular Trap Formation, but Hyphal Killing Is Dependent Only on CR3. Frontiers in Immunology. 9: 1182. PMID 29896200 DOI: 10.3389/Fimmu.2018.01182 |
0.371 |
|
| 2018 |
Clark HL, Minns MS, Sun Y, de Jesus T, Ghannoum MG, Pearlman E. Atovaquone Impairs Growth of Aspergillus and Fusarium Keratitis Isolates by Modulating Mitochondrial Function and Zinc Homeostasis. Investigative Ophthalmology & Visual Science. 59: 1589-1598. PMID 29625485 DOI: 10.1167/Iovs.17-22585 |
0.321 |
|
| 2018 |
Minns MS, Pearlman E. Neutrophils Cause an Intravascular Traffic Jam. Cell Host & Microbe. 23: 6-8. PMID 29324230 DOI: 10.1016/J.Chom.2017.12.011 |
0.376 |
|
| 2017 |
Vareechon C, Zmina SE, Karmakar M, Pearlman E, Rietsch A. Pseudomonas aeruginosa Effector ExoS Inhibits ROS Production in Human Neutrophils. Cell Host & Microbe. 21: 611-618.e5. PMID 28494242 DOI: 10.1016/J.Chom.2017.04.001 |
0.309 |
|
| 2016 |
Hsu D, Taylor P, Fletcher D, van Heeckeren R, Eastman J, van Heeckeren A, Davis P, Chmiel JF, Pearlman E, Bonfield T. CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention. Infection and Immunity. PMID 27271746 DOI: 10.1128/Iai.00284-16 |
0.391 |
|
| 2016 |
Taylor PR, Bonfield TL, Chmiel JF, Pearlman E. Neutrophils from F508del cystic fibrosis patients produce IL-17A and express IL-23 - dependent IL-17RC. Clinical Immunology (Orlando, Fla.). PMID 27155366 DOI: 10.1016/J.Clim.2016.03.016 |
0.413 |
|
| 2016 |
Taylor PR, Roy S, Meszaros EC, Sun Y, Howell SJ, Malemud CJ, Pearlman E. JAK/STAT regulation of Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity. Journal of Leukocyte Biology. PMID 27034404 DOI: 10.1189/Jlb.4A1015-483R |
0.401 |
|
| 2016 |
Karmakar M, Katsnelson MA, Dubyak GR, Pearlman E. Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP. Nature Communications. 7: 10555. PMID 26877061 DOI: 10.1038/Ncomms10555 |
0.409 |
|
| 2016 |
Dietl AM, Amich J, Leal S, Beckmann N, Binder U, Beilhack A, Pearlman E, Haas H. Histidine biosynthesis plays a crucial role in metal homeostasis and virulence of Aspergillus fumigatus. Virulence. 7: 465-76. PMID 26854126 DOI: 10.1080/21505594.2016.1146848 |
0.689 |
|
| 2015 |
Underhill DM, Pearlman E. Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way Street. Immunity. 43: 845-58. PMID 26588778 DOI: 10.1016/J.Immuni.2015.10.023 |
0.381 |
|
| 2015 |
Clark HL, Jhingran A, Sun Y, Vareechon C, de Jesus Carrion S, Skaar EP, Chazin WJ, Calera JA, Hohl TM, Pearlman E. Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 26582948 DOI: 10.4049/Jimmunol.1502037 |
0.396 |
|
| 2015 |
Taylor PR, Pearlman E. IL-17A production by neutrophils. Immunology Letters. PMID 26582721 DOI: 10.1016/J.Imlet.2015.11.006 |
0.32 |
|
| 2015 |
Deng Z, Ma S, Zhou H, Zang A, Fang Y, Li T, Shi H, Liu M, Du M, Taylor PR, Zhu HH, Chen J, Meng G, Li F, Chen C, ... ... Pearlman E, et al. Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses. Nature Immunology. 16: 642-52. PMID 25915733 DOI: 10.1038/Ni.3155 |
0.462 |
|
| 2015 |
Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E. Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux. Journal of Immunology (Baltimore, Md. : 1950). 194: 1763-75. PMID 25609842 DOI: 10.4049/Jimmunol.1401624 |
0.426 |
|
| 2015 |
Karthikeyan RS, Vareechon C, Prajna NV, Dharmalingam K, Pearlman E, Lalitha P. Interleukin 17 expression in peripheral blood neutrophils from fungal keratitis patients and healthy cohorts in southern India. The Journal of Infectious Diseases. 211: 130-4. PMID 25001461 DOI: 10.1093/Infdis/Jiu381 |
0.355 |
|
| 2015 |
Taylor PR, Roy S, Leal SM, Sun Y, Howell SJ, Cobb BA, Li X, Pearlman E. Erratum: Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2 Nature Immunology. 16: 214-214. DOI: 10.1038/Ni0215-214A |
0.679 |
|
| 2014 |
Chandra J, Pearlman E, Ghannoum MA. Animal models to investigate fungal biofilm formation. Methods in Molecular Biology (Clifton, N.J.). 1147: 141-57. PMID 24664831 DOI: 10.1007/978-1-4939-0467-9_10 |
0.349 |
|
| 2014 |
Taylor PR, Leal SM, Sun Y, Pearlman E. Aspergillus and Fusarium corneal infections are regulated by Th17 cells and IL-17-producing neutrophils. Journal of Immunology (Baltimore, Md. : 1950). 192: 3319-27. PMID 24591369 DOI: 10.4049/Jimmunol.1302235 |
0.732 |
|
| 2014 |
Toska J, Sun Y, Carbonell DA, Foster AN, Jacobs MR, Pearlman E, Rietsch A. Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates. Plos One. 9: e86829. PMID 24466261 DOI: 10.1371/Journal.Pone.0086829 |
0.367 |
|
| 2014 |
Taylor PR, Roy S, Leal SM, Sun Y, Howell SJ, Cobb BA, Li X, Pearlman E. Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2. Nature Immunology. 15: 143-51. PMID 24362892 DOI: 10.1038/Ni.2797 |
0.675 |
|
| 2014 |
Ryan SO, Leal SM, Abbott DW, Pearlman E, Cobb BA. Mgat2 ablation in the myeloid lineage leads to defective glycoantigen T cell responses. Glycobiology. 24: 262-71. PMID 24310166 DOI: 10.1093/Glycob/Cwt107 |
0.671 |
|
| 2014 |
Roy S, Karmakar M, Pearlman E. CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo. The Journal of Biological Chemistry. 289: 1174-82. PMID 24275652 DOI: 10.1074/Jbc.M113.523167 |
0.454 |
|
| 2013 |
Carrion Sde J, Leal SM, Ghannoum MA, Aimanianda V, Latgé JP, Pearlman E. The RodA hydrophobin on Aspergillus fumigatus spores masks dectin-1- and dectin-2-dependent responses and enhances fungal survival in vivo. Journal of Immunology (Baltimore, Md. : 1950). 191: 2581-8. PMID 23926321 DOI: 10.4049/Jimmunol.1300748 |
0.721 |
|
| 2013 |
Tang J, Allen Lee C, Du Y, Sun Y, Pearlman E, Sheibani N, Kern TS. MyD88-dependent pathways in leukocytes affect the retina in diabetes. Plos One. 8: e68871. PMID 23874797 DOI: 10.1371/Journal.Pone.0068871 |
0.35 |
|
| 2013 |
Leal SM, Roy S, Vareechon C, Carrion Sd, Clark H, Lopez-Berges MS, Di Pietro A, diPietro A, Schrettl M, Beckmann N, Redl B, Haas H, Pearlman E. Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum. Plos Pathogens. 9: e1003436. PMID 23853581 DOI: 10.1371/Journal.Ppat.1003436 |
0.676 |
|
| 2013 |
Karthikeyan RS, Priya JL, Leal SM, Toska J, Rietsch A, Prajna V, Pearlman E, Lalitha P. Host response and bacterial virulence factor expression in Pseudomonas aeruginosa and Streptococcus pneumoniae corneal ulcers. Plos One. 8: e64867. PMID 23750216 DOI: 10.1371/Journal.Pone.0064867 |
0.698 |
|
| 2013 |
Kohno H, Chen Y, Kevany BM, Pearlman E, Miyagi M, Maeda T, Palczewski K, Maeda A. Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal. The Journal of Biological Chemistry. 288: 15326-41. PMID 23572532 DOI: 10.1074/Jbc.M112.448712 |
0.358 |
|
| 2013 |
Pearlman E, Sun Y, Roy S, Karmakar M, Hise AG, Szczotka-Flynn L, Ghannoum M, Chinnery HR, McMenamin PG, Rietsch A. Host defense at the ocular surface. International Reviews of Immunology. 32: 4-18. PMID 23360155 DOI: 10.3109/08830185.2012.749400 |
0.436 |
|
| 2013 |
Leal SM, Roy S, Vareechon C, Carrion Sd, Clark H, Lopez-Berges MS, Di Pietro A, Schrettl M, Beckmann N, Redl B, Haas H, Pearlman E. Correction: Targeting Iron Acquisition Blocks Infection with the Fungal Pathogens Aspergillus fumigatus and Fusarium oxysporum Plos Pathogens. 9. DOI: 10.1371/annotation/4f388450-90fe-4c65-9b9b-71a2b7935ac0 |
0.638 |
|
| 2012 |
Gentil K, Hoerauf A, Pearlman E. Differential induction of Th2- and Th1-associated responses by filarial antigens and endosymbiotic Wolbachia in a murine model of river blindness. European Journal of Microbiology & Immunology. 2: 134-9. PMID 24672682 DOI: 10.1556/Eujmi.2.2012.2.6 |
0.426 |
|
| 2012 |
Zhou R, Zhang R, Sun Y, Platt S, Szczotka-Flynn L, Pearlman E. Innate immune regulation of Serratia marcescens-induced corneal inflammation and infection. Investigative Ophthalmology & Visual Science. 53: 7382-8. PMID 23033384 DOI: 10.1167/Iovs.12-10238 |
0.482 |
|
| 2012 |
Karmakar M, Sun Y, Hise AG, Rietsch A, Pearlman E. Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1. Journal of Immunology (Baltimore, Md. : 1950). 189: 4231-5. PMID 23024281 DOI: 10.4049/Jimmunol.1201447 |
0.436 |
|
| 2012 |
Leal SM, Vareechon C, Cowden S, Cobb BA, Latgé JP, Momany M, Pearlman E. Fungal antioxidant pathways promote survival against neutrophils during infection. The Journal of Clinical Investigation. 122: 2482-98. PMID 22706306 DOI: 10.1172/Jci63239 |
0.693 |
|
| 2012 |
Leal SM, Pearlman E. The role of cytokines and pathogen recognition molecules in fungal keratitis - Insights from human disease and animal models. Cytokine. 58: 107-11. PMID 22280957 DOI: 10.1016/J.Cyto.2011.12.022 |
0.681 |
|
| 2012 |
Sun Y, Karmakar M, Taylor PR, Rietsch A, Pearlman E. ExoS and ExoT ADP ribosyltransferase activities mediate pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival Journal of Immunology. 188: 1884-1895. PMID 22250085 DOI: 10.4049/Jimmunol.1102148 |
0.416 |
|
| 2012 |
Chinnery HR, McLenachan S, Binz N, Sun Y, Forrester JV, Degli-Esposti MA, Pearlman E, McMenamin PG. TLR9 ligand CpG-ODN applied to the injured mouse cornea elicits retinal inflammation. The American Journal of Pathology. 180: 209-20. PMID 22085974 DOI: 10.1016/J.Ajpath.2011.09.041 |
0.446 |
|
| 2011 |
Karthikeyan RS, Leal SM, Prajna NV, Dharmalingam K, Geiser DM, Pearlman E, Lalitha P. Expression of innate and adaptive immune mediators in human corneal tissue infected with Aspergillus or fusarium. The Journal of Infectious Diseases. 204: 942-50. PMID 21828275 DOI: 10.1093/Infdis/Jir426 |
0.725 |
|
| 2011 |
Tamarozzi F, Halliday A, Gentil K, Hoerauf A, Pearlman E, Taylor MJ. Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment. Clinical Microbiology Reviews. 24: 459-68. PMID 21734243 DOI: 10.1128/Cmr.00057-10 |
0.439 |
|
| 2011 |
Roy S, Sun Y, Pearlman E. Interferon-gamma-induced MD-2 protein expression and lipopolysaccharide (LPS) responsiveness in corneal epithelial cells is mediated by Janus tyrosine kinase-2 activation and direct binding of STAT1 protein to the MD-2 promoter. The Journal of Biological Chemistry. 286: 23753-62. PMID 21572044 DOI: 10.1074/Jbc.M111.219345 |
0.43 |
|
| 2011 |
Shiose S, Chen Y, Okano K, Roy S, Kohno H, Tang J, Pearlman E, Maeda T, Palczewski K, Maeda A. Toll-like receptor 3 is required for development of retinopathy caused by impaired all-trans-retinal clearance in mice. The Journal of Biological Chemistry. 286: 15543-55. PMID 21383019 DOI: 10.1074/Jbc.M111.228551 |
0.378 |
|
| 2011 |
Tu Z, Portillo JA, Howell S, Bu H, Subauste CS, Al-Ubaidi MR, Pearlman E, Lin F. Photoreceptor cells constitutively express functional TLR4. Journal of Neuroimmunology. 230: 183-7. PMID 20801528 DOI: 10.1016/J.Jneuroim.2010.07.022 |
0.34 |
|
| 2010 |
Sun Y, Karmakar M, Roy S, Ramadan RT, Williams SR, Howell S, Shive CL, Han Y, Stopford CM, Rietsch A, Pearlman E. TLR4 and TLR5 on corneal macrophages regulate Pseudomonas aeruginosa keratitis by signaling through MyD88-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 185: 4272-83. PMID 20826748 DOI: 10.4049/Jimmunol.1000874 |
0.492 |
|
| 2010 |
Hayashi Y, Call MK, Chikama T, Liu H, Carlson EC, Sun Y, Pearlman E, Funderburgh JL, Babcock G, Liu CY, Ohashi Y, Kao WW. Lumican is required for neutrophil extravasation following corneal injury and wound healing. Journal of Cell Science. 123: 2987-95. PMID 20699360 DOI: 10.1242/Jcs.068221 |
0.386 |
|
| 2010 |
Leal SM, Cowden S, Hsia YC, Ghannoum MA, Momany M, Pearlman E. Distinct roles for Dectin-1 and TLR4 in the pathogenesis of Aspergillus fumigatus keratitis. Plos Pathogens. 6: e1000976. PMID 20617171 DOI: 10.1371/Journal.Ppat.1000976 |
0.728 |
|
| 2010 |
Carlson EC, Sun Y, Auletta J, Kao WW, Liu CY, Perez VL, Pearlman E. Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient. Journal of Leukocyte Biology. 88: 517-22. PMID 20495072 DOI: 10.1189/Jlb.0310134 |
0.388 |
|
| 2010 |
Szczotka-Flynn LB, Pearlman E, Ghannoum M. Microbial contamination of contact lenses, lens care solutions, and their accessories: a literature review. Eye & Contact Lens. 36: 116-29. PMID 20168237 DOI: 10.1097/Icl.0B013E3181D20Cae |
0.338 |
|
| 2009 |
Du Y, Carlson EC, Funderburgh ML, Birk DE, Pearlman E, Guo N, Kao WW, Funderburgh JL. Stem cell therapy restores transparency to defective murine corneas. Stem Cells (Dayton, Ohio). 27: 1635-42. PMID 19544455 DOI: 10.1002/Stem.91 |
0.333 |
|
| 2009 |
Turner JD, Langley RS, Johnston KL, Gentil K, Ford L, Wu B, Graham M, Sharpley F, Slatko B, Pearlman E, Taylor MJ. Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis. The Journal of Biological Chemistry. 284: 22364-78. PMID 19458089 DOI: 10.1074/Jbc.M901528200 |
0.415 |
|
| 2009 |
Chinnery HR, Carlson EC, Sun Y, Lin M, Burnett SH, Perez VL, McMenamin PG, Pearlman E. Bone marrow chimeras and c-fms conditional ablation (Mafia) mice reveal an essential role for resident myeloid cells in lipopolysaccharide/TLR4-induced corneal inflammation. Journal of Immunology (Baltimore, Md. : 1950). 182: 2738-44. PMID 19234168 DOI: 10.4049/Jimmunol.0803505 |
0.392 |
|
| 2009 |
Gentil K, Pearlman E. Gamma interferon and interleukin-1 receptor 1 regulate neutrophil recruitment to the corneal stroma in a murine model of Onchocerca volvulus keratitis. Infection and Immunity. 77: 1606-12. PMID 19168746 DOI: 10.1128/Iai.00671-08 |
0.425 |
|
| 2009 |
Sun Y, Pearlman E. Inhibition of corneal inflammation by the TLR4 antagonist Eritoran tetrasodium (E5564). Investigative Ophthalmology & Visual Science. 50: 1247-54. PMID 18936141 DOI: 10.1167/Iovs.08-2628 |
0.345 |
|
| 2008 |
Pearlman E, Johnson A, Adhikary G, Sun Y, Chinnery HR, Fox T, Kester M, McMenamin PG. Toll-like receptors at the ocular surface. The Ocular Surface. 6: 108-16. PMID 18781257 DOI: 10.1016/S1542-0124(12)70279-3 |
0.419 |
|
| 2008 |
Tarabishy AB, Aldabagh B, Sun Y, Imamura Y, Mukherjee PK, Lass JH, Ghannoum MA, Pearlman E. MyD88 regulation of Fusarium keratitis is dependent on TLR4 and IL-1R1 but not TLR2. Journal of Immunology (Baltimore, Md. : 1950). 181: 593-600. PMID 18566426 DOI: 10.4049/Jimmunol.181.1.593 |
0.454 |
|
| 2008 |
Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E. Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro. The American Journal of Pathology. 173: 144-53. PMID 18556780 DOI: 10.2353/Ajpath.2008.080081 |
0.318 |
|
| 2008 |
Chinnery HR, Humphries T, Clare A, Dixon AE, Howes K, Moran CB, Scott D, Zakrzewski M, Pearlman E, McMenamin PG. Turnover of bone marrow-derived cells in the irradiated mouse cornea. Immunology. 125: 541-8. PMID 18540963 DOI: 10.1111/J.1365-2567.2008.02868.X |
0.342 |
|
| 2008 |
Sun Y, Fox T, Adhikary G, Kester M, Pearlman E. Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide. Journal of Leukocyte Biology. 83: 1512-21. PMID 18372342 DOI: 10.1189/Jlb.0108076 |
0.353 |
|
| 2008 |
Adhikary G, Sun Y, Pearlman E. C-Jun NH2 terminal kinase (JNK) is an essential mediator of Toll-like receptor 2-induced corneal inflammation. Journal of Leukocyte Biology. 83: 991-7. PMID 18218857 DOI: 10.1189/Jlb.1107783 |
0.43 |
|
| 2008 |
Johnson AC, Li X, Pearlman E. MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase. The Journal of Biological Chemistry. 283: 3988-96. PMID 18057004 DOI: 10.1074/Jbc.M707264200 |
0.418 |
|
| 2007 |
Carlson EC, Lin M, Liu CY, Kao WW, Perez VL, Pearlman E. Keratocan and lumican regulate neutrophil infiltration and corneal clarity in lipopolysaccharide-induced keratitis by direct interaction with CXCL1. The Journal of Biological Chemistry. 282: 35502-9. PMID 17911102 DOI: 10.1074/Jbc.M705823200 |
0.383 |
|
| 2007 |
Gillette-Ferguson I, Daehnel K, Hise AG, Sun Y, Carlson E, Diaconu E, McGarry HF, Taylor MJ, Pearlman E. Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis. Infection and Immunity. 75: 5908-15. PMID 17875630 DOI: 10.1128/Iai.00991-07 |
0.407 |
|
| 2007 |
Daehnel K, Gillette-Ferguson I, Hise AG, Diaconu E, Harling MJ, Heinzel FP, Pearlman E. Filaria/Wolbachia activation of dendritic cells and development of Th1-associated responses is dependent on Toll-like receptor 2 in a mouse model of ocular onchocerciasis (river blindness). Parasite Immunology. 29: 455-65. PMID 17727569 DOI: 10.1111/J.1365-3024.2007.00962.X |
0.457 |
|
| 2007 |
Chinnery HR, Ruitenberg MJ, Plant GW, Pearlman E, Jung S, McMenamin PG. The chemokine receptor CX3CR1 mediates homing of MHC class II-positive cells to the normal mouse corneal epithelium. Investigative Ophthalmology & Visual Science. 48: 1568-74. PMID 17389486 DOI: 10.1167/Iovs.06-0746 |
0.333 |
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| 2007 |
Pearlman E, Gillette-Ferguson I. Onchocerca volvulus, Wolbachia and river blindness. Chemical Immunology and Allergy. 92: 254-65. PMID 17264501 DOI: 10.1159/000099276 |
0.406 |
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| 2007 |
Hise AG, Daehnel K, Gillette-Ferguson I, Cho E, McGarry HF, Taylor MJ, Golenbock DT, Fitzgerald KA, Kazura JW, Pearlman E. Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM. Journal of Immunology (Baltimore, Md. : 1950). 178: 1068-76. PMID 17202370 DOI: 10.4049/Jimmunol.178.2.1068 |
0.46 |
|
| 2007 |
Lin M, Carlson E, Diaconu E, Pearlman E. CXCL1/KC and CXCL5/LIX are selectively produced by corneal fibroblasts and mediate neutrophil infiltration to the corneal stroma in LPS keratitis. Journal of Leukocyte Biology. 81: 786-92. PMID 17110418 DOI: 10.1189/Jlb.0806502 |
0.357 |
|
| 2006 |
Sun Y, Hise AG, Kalsow CM, Pearlman E. Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88. Infection and Immunity. 74: 5325-32. PMID 16926427 DOI: 10.1128/Iai.00645-06 |
0.432 |
|
| 2006 |
Gillette-Ferguson I, Hise AG, Sun Y, Diaconu E, McGarry HF, Taylor MJ, Pearlman E. Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88. Infection and Immunity. 74: 2442-5. PMID 16552075 DOI: 10.1128/Iai.74.4.2442-2445.2006 |
0.378 |
|
| 2005 |
Johnson A, Pearlman E. Toll-like receptors in the cornea. The Ocular Surface. 3: S187-9. PMID 17216116 DOI: 10.1016/S1542-0124(12)70252-5 |
0.354 |
|
| 2005 |
McDermott AM, Perez V, Huang AJ, Pflugfelder SC, Stern ME, Baudouin C, Beuerman RW, Burns AR, Calder VL, Calonge M, Chodosh J, Coster DJ, Dana R, Hazlett LD, Jones DB, ... ... Pearlman E, et al. Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium. The Ocular Surface. 3: S131-8. PMID 17216102 DOI: 10.1016/S1542-0124(12)70238-0 |
0.305 |
|
| 2005 |
Johnson AC, Heinzel FP, Diaconu E, Sun Y, Hise AG, Golenbock D, Lass JH, Pearlman E. Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. Investigative Ophthalmology & Visual Science. 46: 589-95. PMID 15671286 DOI: 10.1167/Iovs.04-1077 |
0.414 |
|
| 2005 |
Pearlman E. Experimental onchocercal keratitis. Parasitology Today (Personal Ed.). 12: 261-7. PMID 15275190 DOI: 10.1016/0169-4758(96)10026-0 |
0.372 |
|
| 2004 |
Gillette-Ferguson I, Hise AG, McGarry HF, Turner J, Esposito A, Sun Y, Diaconu E, Taylor MJ, Pearlman E. Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness). Infection and Immunity. 72: 5687-92. PMID 15385467 DOI: 10.1128/Iai.72.10.5687-5692.2004 |
0.341 |
|
| 2004 |
Hise AG, Gillette-Ferguson I, Pearlman E. The role of endosymbiotic Wolbachia bacteria in filarial disease. Cellular Microbiology. 6: 97-104. PMID 14706096 DOI: 10.1046/J.1462-5822.2003.00350.X |
0.408 |
|
| 2003 |
Hise AG, Gillette-Ferguson I, Pearlman E. Immunopathogenesis of Onchocerca volvulus keratitis (river blindness): a novel role for TLR4 and endosymbiotic Wolbachia bacteria. Journal of Endotoxin Research. 9: 390-4. PMID 14733727 DOI: 10.1179/096805103225002746 |
0.457 |
|
| 2003 |
Pearlman E. Immunopathogenesis of Onchocerca volvulus keratitis (river blindness): a novel role for endosymbiotic Wolbachia bacteria. Medical Microbiology and Immunology. 192: 57-60. PMID 12592565 DOI: 10.1007/S00430-002-0160-Z |
0.419 |
|
| 2002 |
Hall LR, Berger RB, Diaconu E, Pearlman E. Onchocerca volvulus keratitis (river blindness) is exacerbated in BALB/c IL-4 gene knockout mice Cellular Immunology. 216: 1-5. PMID 12381344 DOI: 10.1016/S0008-8749(02)00500-2 |
0.376 |
|
| 2002 |
Berger RB, Blackwell NM, Lass JH, Diaconu E, Pearlman E. IL-4 and IL-13 regulation of ICAM-1 expression and eosinophil recruitment in Onchocerca volvulus keratitis. Investigative Ophthalmology & Visual Science. 43: 2992-7. PMID 12202520 |
0.301 |
|
| 2002 |
Saint André AV, Blackwell NM, Hall LR, Hoerauf A, Brattig NW, Volkmann L, Taylor MJ, Ford L, Hise AG, Lass JH, Diaconu E, Pearlman E. The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness Science. 295: 1892-1895. PMID 11884755 DOI: 10.1126/Science.1068732 |
0.447 |
|
| 2001 |
Hall LR, Diaconu E, Pearlman E. A dominant role for Fcγ receptors in antibody-dependent corneal inflammation Journal of Immunology. 167: 919-925. PMID 11441099 DOI: 10.4049/Jimmunol.167.2.919 |
0.383 |
|
| 2001 |
Kaifi JT, Diaconu E, Pearlman E. Distinct roles for PECAM-1, ICAM-1, and VCAM-1 in recruitment of neutrophils and eosinophils to the cornea in ocular onchocerciasis (river blindness). Journal of Immunology (Baltimore, Md. : 1950). 166: 6795-801. PMID 11359838 DOI: 10.4049/Jimmunol.166.11.6795 |
0.364 |
|
| 2001 |
Hall LR, Diaconu E, Patel R, Pearlman E. CXC chemokine receptor 2 but not C-C chemokine receptor 1 expression is essential for neutrophil recruitment to the cornea in helminth-mediated keratitis (river blindness) Journal of Immunology. 166: 4035-4041. PMID 11238651 DOI: 10.4049/Jimmunol.166.6.4035 |
0.413 |
|
| 2001 |
Mehlotra RK, Hall LR, Haxhiu MA, Pearlman E. Reciprocal immunomodulatory effects of gamma interferon and interleukin-4 on filaria-induced airway hyperresponsiveness Infection and Immunity. 69: 1463-1468. PMID 11179313 DOI: 10.1128/Iai.69.3.1463-1468.2001 |
0.401 |
|
| 2000 |
Pearlman E, Hall LR. Immune mechanisms in Onchocerca volvulus-mediated corneal disease (river blindness) Parasite Immunology. 22: 625-631. PMID 11123754 DOI: 10.1046/J.1365-3024.2000.00345.X |
0.42 |
|
| 2000 |
Al-Qaoud KM, Pearlman E, Hartung T, Klukowski J, Fleischer B, Hoerauf A. A new mechanism for IL-5-dependent helminth control: neutrophil accumulation and neutrophil-mediated worm encapsulation in murine filariasis are abolished in the absence of IL-5. International Immunology. 12: 899-908. PMID 10837417 DOI: 10.1093/Intimm/12.6.899 |
0.412 |
|
| 2000 |
Martin DL, King CL, Pearlman E, Strine E, Heinzel FP. IFN-gamma is necessary but not sufficient for anti-CD40 antibody-mediated inhibition of the Th2 response to Schistosoma mansoni eggs. Journal of Immunology (Baltimore, Md. : 1950). 164: 779-85. PMID 10623823 DOI: 10.4049/Jimmunol.164.2.779 |
0.394 |
|
| 1999 |
Pearlman E, Toé L, Boatin BA, Gilles AA, Higgins AW, Unnasch TR. Eotaxin expression in Onchocerca volvulus-induced dermatitis after topical application of diethylcarbamazine Journal of Infectious Diseases. 180: 1394-1397. PMID 10479181 DOI: 10.1086/315041 |
0.307 |
|
| 1999 |
Pearlman E, Garhart CA, Grand DJ, Diaconu E, Strine ER, Hall LR. Temporal recruitment of neutrophils and eosinophils to the skin in a murine model for onchocercal dermatitis. The American Journal of Tropical Medicine and Hygiene. 61: 14-8. PMID 10432048 DOI: 10.4269/Ajtmh.1999.61.14 |
0.347 |
|
| 1999 |
Mountford AP, Pearlman E. Interleukin-12 and the host response to parasitic helminths; the paradoxical effect on protective immunity and immunopathology. Parasite Immunology. 20: 509-17. PMID 9988307 DOI: 10.1046/J.1365-3024.1998.00182.X |
0.458 |
|
| 1999 |
Hall LR, Pearlman E. Pathogenesis of Onchocercal Keratitis (River Blindness) Clinical Microbiology Reviews. 12: 445-453. DOI: 10.1128/Cmr.12.3.445 |
0.386 |
|
| 1998 |
Mehlotra RK, Hall LR, Higgins AW, Dreshaj IA, Haxhiu MA, Kazura JW, Pearlman E. Interleukin-12 suppresses filaria-induced pulmonary eosinophilia, deposition of major basic protein and airway hyperresponsiveness Parasite Immunology. 20: 455-462. PMID 9797506 DOI: 10.1046/J.1365-3024.1998.00174.X |
0.396 |
|
| 1998 |
Hall LR, Mehlotra RK, Higgins AW, Haxhiu MA, Pearlman E. An essential role for interleukin-5 and eosinophils in helminth-induced airway hyperresponsiveness Infection and Immunity. 66: 4425-4430. PMID 9712797 DOI: 10.1128/Iai.66.9.4425-4430.1998 |
0.425 |
|
| 1998 |
Matthews AN, Friend DS, Zimmermann N, Sarafi MN, Luster AD, Pearlman E, Wert SE, Rothenberg ME. Eotaxin is required for the baseline level of tissue eosinophils. Proceedings of the National Academy of Sciences of the United States of America. 95: 6273-8. PMID 9600955 DOI: 10.1073/Pnas.95.11.6273 |
0.348 |
|
| 1998 |
Hall LR, Mehlotra RK, Higgins AW, Haxhiu MA, Pearlman E. An Essential Role for Interleukin-5 and Eosinophils in Helminth-Induced Airway Hyperresponsiveness Infection and Immunity. 66: 4425-4430. DOI: 10.1128/IAI.66.9.4425-4430.1998 |
0.313 |
|
| 1997 |
Bardenstein DS, Lass JH, Kazura JW, Pearlman E. Pleomorphism of stromal eosinophils in murine experimental onchocercal keratitis. Ocular Immunology and Inflammation. 5: 157-63. PMID 9326760 DOI: 10.3109/09273949709116890 |
0.319 |
|
| 1997 |
Pearlman E, Diaconu E, Hazlett FE, Merriweather A, Unnasch TR. Identification of an epitope of a recombinant Onchocerca volvulus protein that induces corneal pathology Molecular and Biochemical Parasitology. 89: 123-135. PMID 9297706 DOI: 10.1016/S0166-6851(97)00112-6 |
0.341 |
|
| 1997 |
Pearlman E. Immunopathology of onchocerciasis: a role for eosinophils in onchocercal dermatitis and keratitis. Chemical Immunology. 66: 26-40. PMID 9103664 DOI: 10.1159/000058664 |
0.412 |
|
| 1997 |
Rothenberg ME, MacLean JA, Pearlman E, Luster AD, Leder P. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia. The Journal of Experimental Medicine. 185: 785-90. PMID 9034156 DOI: 10.1084/Jem.185.4.785 |
0.388 |
|
| 1996 |
Pearlman E, Lass JH, Bardenstein DS, Diaconu E, Hazlett FE, Albright J, Higgins AW, Kazura JW. Onchocerca volvulus-mediated keratitis: cytokine production by IL-4-deficient mice. Experimental Parasitology. 84: 274-81. PMID 8932777 DOI: 10.1006/Expr.1996.0113 |
0.413 |
|
| 1995 |
Pearlman E, Lass JH, Bardenstein DS, Kopf M, Hazlett FE, Diaconu E, Kazura JW. Interleukin 4 and T helper type 2 cells are required for development of experimental onchocercal keratitis (river blindness). The Journal of Experimental Medicine. 182: 931-40. PMID 7561696 DOI: 10.1084/Jem.182.4.931 |
0.447 |
|
| 1993 |
Pearlman E, Kroeze WK, Hazlett FE, Chen SS, Mawhorter SD, Boom WH, Kazura JW. Brugia malayi: acquired resistance to microfilariae in BALB/c mice correlates with local Th2 responses. Experimental Parasitology. 76: 200-8. PMID 8454029 DOI: 10.1006/Expr.1993.1023 |
0.416 |
|
| 1993 |
Pearlman E, Hazlett FE, Boom WH, Kazura JW. Induction of murine T-helper-cell responses to the filarial nematode Brugia malayi. Infection and Immunity. 61: 1105-12. PMID 8094378 DOI: 10.1128/Iai.61.3.1105-1112.1993 |
0.406 |
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