M Luisa Iruela-Arispe - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology

135 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sunshine HL, Cicchetto AC, Kaczor-Urbanowicz KE, Ma F, Pi D, Symons C, Turner M, Shukla V, Christofk HR, Vallim TA, Iruela-Arispe ML. Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins. Cell Reports. 43: 113627. PMID 38157296 DOI: 10.1016/j.celrep.2023.113627  0.406
2023 Fernández-Chacón M, Mühleder S, Regano A, Garcia-Ortega L, Rocha SF, Torroja C, Sanchez-Muñoz MS, Lytvyn M, Casquero-Garcia V, De Andrés-Laguillo M, Muhl L, Orlich MM, Gaengel K, Camafeita E, Vázquez J, ... ... Iruela-Arispe ML, et al. Incongruence between transcriptional and vascular pathophysiological cell states. Nature Cardiovascular Research. 2: 2023530-549. PMID 37745941 DOI: 10.1038/s44161-023-00272-4  0.394
2023 Iruela-Arispe ML. How to target vascular leakage in retinopathy: could a lipid tighten the pipes? Embo Molecular Medicine. e17520. PMID 36975378 DOI: 10.15252/emmm.202317520  0.306
2022 Salvador J, Iruela-Arispe ML. Nuclear Mechanosensation and Mechanotransduction in Vascular Cells. Frontiers in Cell and Developmental Biology. 10: 905927. PMID 35784481 DOI: 10.3389/fcell.2022.905927  0.346
2020 Evans CE, Iruela-Arispe ML, Zhao YY. Mechanisms of Endothelial Regeneration and Vascular Repair and Their Application to Regenerative Medicine. The American Journal of Pathology. PMID 33069720 DOI: 10.1016/j.ajpath.2020.10.001  0.37
2020 Chen G, Li Z, Liu Y, Chen D, Beers J, Cudrici C, Ferrante EA, Schwartzbeck R, Dmitrieva N, Yang D, Zou J, Iruela-Arispe ML, Boehm M. Generation of human induced pluripotent stem cells (NIHTVBi004-A, NIHTVBi005-A, NIHTVBi006-A, NIHTVBi007-A, NIHTVBi008-A) from 5 CADASIL patients with NOTCH3 mutation. Stem Cell Research. 45: 101821. PMID 32344328 DOI: 10.1016/J.Scr.2020.101821  0.319
2020 Hernandez GE, Iruela-Arispe ML. The many flavors of monocyte/macrophage--endothelial cell interactions. Current Opinion in Hematology. PMID 32167947 DOI: 10.1097/Moh.0000000000000573  0.333
2019 Romay MC, Toro C, Iruela-Arispe ML. Emerging molecular mechanisms of vascular dementia. Current Opinion in Hematology. PMID 30883434 DOI: 10.1097/Moh.0000000000000502  0.325
2019 Iruela-Arispe ML. A focus on vascular malformations. Current Opinion in Hematology. PMID 30870249 DOI: 10.1097/Moh.0000000000000504  0.442
2018 Iruela-Arispe ML. A dual origin for blood vessels. Nature. 562: 195-197. PMID 30291309 DOI: 10.1038/D41586-018-06199-2  0.403
2018 Iruela-Arispe ML. Pumping blood with self-reliance and cooperation. The Journal of Experimental Medicine. PMID 30228158 DOI: 10.1084/Jem.20181537  0.458
2018 McDonald AI, Shirali AS, Aragón R, Ma F, Hernandez G, Vaughn DA, Mack JJ, Lim TY, Sunshine H, Zhao P, Kalinichenko V, Hai T, Pelegrini M, Ardehali R, Iruela-Arispe ML. Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities. Cell Stem Cell. 23: 210-225.e6. PMID 30075129 DOI: 10.1016/J.Stem.2018.07.011  0.461
2018 Chattopadhyay A, Yang X, Mukherjee P, Sulaiman D, Fogelman HR, Grijalva V, Dubinett S, Wasler TC, Paul MK, Salehi-Rad R, Mack JJ, Iruela-Arispe ML, Navab M, Fogelman AM, Reddy ST. Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer. Scientific Reports. 8: 9032. PMID 29899427 DOI: 10.1038/S41598-018-26755-0  0.303
2018 Hilfenhaus G, Nguyen DP, Freshman J, Prajapati D, Ma F, Song D, Ziyad S, Cuadrado M, Pellegrini M, Bustelo XR, Iruela-Arispe ML. Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers. The Journal of Cell Biology. PMID 29858212 DOI: 10.1083/Jcb.201706041  0.486
2018 Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, ... ... Iruela-Arispe ML, et al. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. PMID 29766399 DOI: 10.1007/S10456-018-9613-X  0.404
2018 Freitas VM, Hilfenhaus G, Iruela-Arispe ML. Metastasis of Circulating Tumor Cells: Speed Matters. Developmental Cell. 45: 3-5. PMID 29634934 DOI: 10.1016/J.Devcel.2018.03.005  0.341
2018 Shirali AS, Romay MC, McDonald AI, Su T, Steel ME, Iruela-Arispe ML. A multi-step transcriptional cascade underlies vascular regeneration in vivo. Scientific Reports. 8: 5430. PMID 29615716 DOI: 10.1038/S41598-018-23653-3  0.396
2018 Li L, Zeng Q, Bhutkar A, Galván JA, Karamitopoulou E, Noordermeer D, Peng MW, Piersigilli A, Perren A, Zlobec I, Robinson H, Iruela-Arispe ML, Hanahan D. GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth. Cancer Cell. PMID 29606348 DOI: 10.1016/J.Ccell.2018.02.011  0.344
2018 Mack JJ, Iruela-Arispe ML. NOTCH regulation of the endothelial cell phenotype. Current Opinion in Hematology. PMID 29547401 DOI: 10.1097/Moh.0000000000000425  0.453
2018 Sereti KI, Nguyen NB, Kamran P, Zhao P, Ranjbarvaziri S, Park S, Sabri S, Engel JL, Sung K, Kulkarni RP, Ding Y, Hsiai TK, Plath K, Ernst J, Sahoo D, ... ... Iruela-Arispe ML, et al. Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. Nature Communications. 9: 754. PMID 29467410 DOI: 10.1038/S41467-018-02891-Z  0.309
2018 Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML. A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Reports. 22: 1211-1224. PMID 29386109 DOI: 10.1016/J.Celrep.2018.01.017  0.351
2017 Mack JJ, Mosqueiro TS, Archer BJ, Jones WM, Sunshine H, Faas GC, Briot A, Aragón RL, Su T, Romay MC, McDonald AI, Kuo CH, Lizama CO, Lane TF, Zovein AC, ... ... Iruela-Arispe ML, et al. NOTCH1 is a mechanosensor in adult arteries. Nature Communications. 8: 1620. PMID 29158473 DOI: 10.1038/S41467-017-01741-8  0.405
2016 Shirali AS, McDonald AI, Mack JJ, Iruela-Arispe ML. Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model. Journal of Visualized Experiments : Jove. PMID 27911412 DOI: 10.3791/54755  0.393
2016 Inkeles MS, Teles RM, Pouldar D, Andrade PR, Madigan CA, Lopez D, Ambrose M, Noursadeghi M, Sarno EN, Rea TH, Ochoa MT, Iruela-Arispe ML, Swindell WR, Ottenhoff TH, Geluk A, et al. Cell-type deconvolution with immune pathways identifies gene networks of host defense and immunopathology in leprosy. Jci Insight. 1: e88843. PMID 27699251 DOI: 10.1172/Jci.Insight.88843  0.312
2016 He H, Mack JJ, Güç E, Warren CM, Squadrito ML, Kilarski WW, Baer C, Freshman RD, McDonald AI, Ziyad S, Swartz MA, De Palma M, Iruela-Arispe ML. Perivascular Macrophages Limit Permeability. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27634833 DOI: 10.1161/Atvbaha.116.307592  0.404
2016 Briot A, Bouloumié A, Iruela-Arispe ML. Notch, lipids, and endothelial cells. Current Opinion in Lipidology. PMID 27454451 DOI: 10.1097/Mol.0000000000000337  0.417
2016 Uebelhoer M, Iruela-Arispe ML. Cross-talk between signaling and metabolism in the vasculature. Vascular Pharmacology. PMID 27291139 DOI: 10.1016/J.Vph.2016.06.002  0.354
2015 Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, ... ... Iruela-Arispe ML, et al. Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis. The Journal of Experimental Medicine. PMID 26552708 DOI: 10.1084/Jem.20150603  0.435
2015 Hernández-García R, Iruela-Arispe ML, Reyes-Cruz G, Vázquez-Prado J. Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells. Vascular Pharmacology. 74: 60-72. PMID 26471833 DOI: 10.1016/J.Vph.2015.10.003  0.498
2015 Moughon D, He H, Schokrpur S, Jiang ZK, Yaqoob M, David J, Lin C, Iruela-Arispe ML, Dorigo O, Wu L. Macrophage Blockade Using CSF1R Inhibitors Reverses The Vascular Leakage Underlying Malignant Ascites In Late-Stage Epithelial Ovarian Cancer. Cancer Research. PMID 26471360 DOI: 10.1158/0008-5472.Can-14-3373  0.39
2015 McDonald AI, Iruela-Arispe ML. Healing arterial ulcers: Endothelial lining regeneration upon vascular denudation injury. Vascular Pharmacology. 72: 9-15. PMID 26093336 DOI: 10.1016/J.Vph.2015.06.007  0.423
2015 Domigan CK, Warren CM, Antanesian V, Happel K, Ziyad S, Lee S, Krall A, Duan L, Torres-Collado AX, Castellani LW, Elashoff D, Christofk HR, van der Bliek AM, Potente M, Iruela-Arispe ML. Autocrine VEGF maintains endothelial survival through regulation of metabolism and autophagy. Journal of Cell Science. 128: 2236-48. PMID 25956888 DOI: 10.1242/Jcs.163774  0.489
2015 Simons M, Alitalo K, Annex BH, Augustin HG, Beam C, Berk BC, Byzova T, Carmeliet P, Chilian W, Cooke JP, Davis GE, Eichmann A, Iruela-Arispe ML, Keshet E, Sinusas AJ, et al. State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circulation Research. 116: e99-132. PMID 25931450 DOI: 10.1161/Res.0000000000000054  0.488
2015 Rodríguez-Manzaneque JC, Fernández-Rodríguez R, Rodríguez-Baena FJ, Iruela-Arispe ML. ADAMTS proteases in vascular biology. Matrix Biology : Journal of the International Society For Matrix Biology. 44: 38-45. PMID 25698314 DOI: 10.1016/J.Matbio.2015.02.004  0.435
2015 Briot A, Iruela-Arispe ML. Blockade of specific NOTCH ligands: a new promising approach in cancer therapy. Cancer Discovery. 5: 112-4. PMID 25656896 DOI: 10.1158/2159-8290.Cd-14-1501  0.319
2015 Domigan CK, Ziyad S, Iruela-Arispe ML. Canonical and noncanonical vascular endothelial growth factor pathways: new developments in biology and signal transduction. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 30-9. PMID 25278287 DOI: 10.1161/Atvbaha.114.303215  0.46
2014 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML. Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Developmental Cell. 31: 707-21. PMID 25535917 DOI: 10.1016/J.Devcel.2014.11.023  0.441
2014 Domigan CK, Iruela-Arispe ML. Stealing VEGF from thy neighbor. Cell. 159: 473-4. PMID 25417099 DOI: 10.1016/J.Cell.2014.10.008  0.443
2014 Warren CM, Iruela-Arispe ML. Podosome rosettes precede vascular sprouts in tumour angiogenesis. Nature Cell Biology. 16: 928-30. PMID 25271481 DOI: 10.1038/Ncb3044  0.476
2014 Nowak-Sliwinska P, Segura T, Iruela-Arispe ML. The chicken chorioallantoic membrane model in biology, medicine and bioengineering. Angiogenesis. 17: 779-804. PMID 25138280 DOI: 10.1007/S10456-014-9440-7  0.383
2014 Michael IP, Westenskow PD, Hacibekiroglu S, Greenwald AC, Ballios BG, Kurihara T, Li Z, Warren CM, Zhang P, Aguilar E, Donaldson L, Marchetti V, Baba T, Hussein SM, Sung HK, ... Iruela-Arispe ML, et al. Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye. Embo Molecular Medicine. 6: 604-23. PMID 24705878 DOI: 10.1002/Emmm.201303708  0.437
2014 Goddard LM, Murphy TJ, Org T, Enciso JM, Hashimoto-Partyka MK, Warren CM, Domigan CK, McDonald AI, He H, Sanchez LA, Allen NC, Orsenigo F, Chao LC, Dejana E, Tontonoz P, ... ... Iruela-Arispe ML, et al. Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation. Cell. 156: 549-62. PMID 24485460 DOI: 10.1016/J.Cell.2013.12.025  0.476
2014 Warren CM, Ziyad S, Briot A, Der A, Iruela-Arispe ML. A ligand-independent VEGFR2 signaling pathway limits angiogenic responses in diabetes. Science Signaling. 7: ra1. PMID 24399295 DOI: 10.1126/Scisignal.2004235  0.451
2013 Corada M, Orsenigo F, Morini MF, Pitulescu ME, Bhat G, Nyqvist D, Breviario F, Conti V, Briot A, Iruela-Arispe ML, Adams RH, Dejana E. Sox17 is indispensable for acquisition and maintenance of arterial identity. Nature Communications. 4: 2609. PMID 24153254 DOI: 10.1038/Ncomms3609  0.406
2013 Milde F, Lauw S, Koumoutsakos P, Iruela-Arispe ML. The mouse retina in 3D: quantification of vascular growth and remodeling. Integrative Biology : Quantitative Biosciences From Nano to Macro. 5: 1426-38. PMID 24136100 DOI: 10.1039/C3Ib40085A  0.43
2013 Turlo KA, Scapa J, Bagher P, Jones AW, Feil R, Korthuis RJ, Segal SS, Iruela-Arispe ML. β1-integrin is essential for vasoregulation and smooth muscle survival in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2325-35. PMID 23887637 DOI: 10.1161/Atvbaha.112.300648  0.368
2013 Goddard LM, Ton AN, Org T, Mikkola HK, Iruela-Arispe ML. Selective suppression of endothelial cytokine production by progesterone receptor. Vascular Pharmacology. 59: 36-43. PMID 23747964 DOI: 10.1016/J.Vph.2013.06.001  0.384
2013 Roodhart JM, He H, Daenen LG, Monvoisin A, Barber CL, van Amersfoort M, Hofmann JJ, Radtke F, Lane TF, Voest EE, Iruela-Arispe ML. Notch1 regulates angio-supportive bone marrow-derived cells in mice: relevance to chemoresistance. Blood. 122: 143-53. PMID 23690447 DOI: 10.1182/Blood-2012-11-459347  0.409
2013 Baer C, Squadrito ML, Iruela-Arispe ML, De Palma M. Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches. Experimental Cell Research. 319: 1626-34. PMID 23542777 DOI: 10.1016/J.Yexcr.2013.03.026  0.492
2013 Cristofaro B, Shi Y, Faria M, Suchting S, Leroyer AS, Trindade A, Duarte A, Zovein AC, Iruela-Arispe ML, Nih LR, Kubis N, Henrion D, Loufrani L, Todiras M, Schleifenbaum J, et al. Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models. Development (Cambridge, England). 140: 1720-9. PMID 23533173 DOI: 10.1242/Dev.092304  0.33
2013 DeFalco T, Saraswathula A, Briot A, Iruela-Arispe ML, Capel B. Testosterone levels influence mouse fetal leydig cell progenitors through notch signaling Biology of Reproduction. 88. PMID 23467742 DOI: 10.1095/Biolreprod.112.106138  0.367
2013 Goddard LM, Iruela-Arispe ML. Cellular and molecular regulation of vascular permeability. Thrombosis and Haemostasis. 109: 407-15. PMID 23389236 DOI: 10.1160/Th12-09-0678  0.364
2012 Hofmann JJ, Briot A, Enciso J, Zovein AC, Ren S, Zhang ZW, Radtke F, Simons M, Wang Y, Iruela-Arispe ML. Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome. Development (Cambridge, England). 139: 4449-60. PMID 23095891 DOI: 10.1242/Dev.084871  0.372
2012 He H, Xu J, Warren CM, Duan D, Li X, Wu L, Iruela-Arispe ML. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood. 120: 3152-62. PMID 22919031 DOI: 10.1182/Blood-2012-04-422758  0.475
2012 Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, ... ... Iruela-Arispe ML, et al. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nature Medicine. 18: 967-73. PMID 22581286 DOI: 10.1038/Nm.2759  0.467
2012 Domigan CK, Iruela-Arispe ML. Recent advances in vascular development. Current Opinion in Hematology. 19: 176-83. PMID 22406825 DOI: 10.1097/Moh.0B013E3283523E90  0.489
2012 Chhabra A, Lechner AJ, Ueno M, Acharya A, Van Handel B, Wang Y, Iruela-Arispe ML, Tallquist MD, Mikkola HK. Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling. Developmental Cell. 22: 651-9. PMID 22387002 DOI: 10.1016/J.Devcel.2011.12.022  0.338
2012 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM. CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. Plos One. 7: e30562. PMID 22363445 DOI: 10.1371/Journal.Pone.0030562  0.519
2012 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS. Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 303-14. PMID 22183742 DOI: 10.1002/Dvdy.23716  0.302
2012 Scheppke L, Murphy EA, Zarpellon A, Hofmann JJ, Merkulova A, Shields DJ, Weis SM, Byzova TV, Ruggeri ZM, Iruela-Arispe ML, Cheresh DA. Notch promotes vascular maturation by inducing integrin-mediated smooth muscle cell adhesion to the endothelial basement membrane. Blood. 119: 2149-58. PMID 22134168 DOI: 10.1182/Blood-2011-04-348706  0.5
2011 Ziyad S, Iruela-Arispe ML. Molecular mechanisms of tumor angiogenesis. Genes & Cancer. 2: 1085-96. PMID 22866200 DOI: 10.1177/1947601911432334  0.44
2011 Anderson SM, Shergill B, Barry ZT, Manousiouthakis E, Chen TT, Botvinick E, Platt MO, Iruela-Arispe ML, Segura T. VEGF internalization is not required for VEGFR-2 phosphorylation in bioengineered surfaces with covalently linked VEGF. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 887-96. PMID 21826315 DOI: 10.1039/C1Ib00037C  0.476
2011 Iruela-Arispe ML. LUMENating blood vessels. Developmental Cell. 20: 412-4. PMID 21497753 DOI: 10.1016/J.Devcel.2011.03.020  0.438
2010 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML. Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development (Cambridge, England). 137: 4061-72. PMID 21062863 DOI: 10.1242/Dev.052118  0.322
2010 Turlo KA, Gallaher SD, Vora R, Laski FA, Iruela-Arispe ML. When Cre-mediated recombination in mice does not result in protein loss. Genetics. 186: 959-67. PMID 20813881 DOI: 10.1534/Genetics.110.121608  0.301
2010 Zovein AC, Turlo KA, Ponec RM, Lynch MR, Chen KC, Hofmann JJ, Cox TC, Gasson JC, Iruela-Arispe ML. Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. Blood. 116: 3435-44. PMID 20699440 DOI: 10.1182/Blood-2010-04-279497  0.361
2010 da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V, Germain MA, Reynolds AR, Jones DT, Watson AR, Jones JL, Harris A, Hart IR, ... Iruela-Arispe ML, et al. Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. The American Journal of Pathology. 177: 1534-48. PMID 20639457 DOI: 10.2353/Ajpath.2010.100043  0.504
2010 Corada M, Nyqvist D, Orsenigo F, Caprini A, Giampietro C, Taketo MM, Iruela-Arispe ML, Adams RH, Dejana E. The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Developmental Cell. 18: 938-49. PMID 20627076 DOI: 10.1016/J.Devcel.2010.05.006  0.411
2010 Warren CM, Iruela-Arispe ML. Signaling circuitry in vascular morphogenesis. Current Opinion in Hematology. 17: 213-8. PMID 20216211 DOI: 10.1097/Moh.0B013E32833865D1  0.492
2010 Chen TT, Luque A, Lee S, Anderson SM, Segura T, Iruela-Arispe ML. Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells. The Journal of Cell Biology. 188: 595-609. PMID 20176926 DOI: 10.1083/Jcb.200906044  0.462
2010 Arroyo AG, Iruela-Arispe ML. Extracellular matrix, inflammation, and the angiogenic response. Cardiovascular Research. 86: 226-35. PMID 20154066 DOI: 10.1093/Cvr/Cvq049  0.417
2010 Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML. Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Developmental Cell. 18: 39-51. PMID 20152176 DOI: 10.1016/J.Devcel.2009.12.006  0.426
2010 Priceman SJ, Sung JL, Shaposhnik Z, Burton JB, Torres-Collado AX, Moughon DL, Johnson M, Lusis AJ, Cohen DA, Iruela-Arispe ML, Wu L. Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy. Blood. 115: 1461-71. PMID 20008303 DOI: 10.1182/Blood-2009-08-237412  0.355
2010 Karl DL, Lee YJ, Koch M, Torres-Collado AX, Fernando NT, Rothrock C, Kuruppu D, Ryeom S, Iruela-Arispe ML, Yoon SS. Abstract 2325: Thrombospondin 1 inhibits angiogenesis in liver metastases but not lung metastases due to differential cleavage activity of ADAMTS1 Cancer Research. 70: 2325-2325. DOI: 10.1158/1538-7445.Am10-2325  0.316
2009 Anderson SM, Chen TT, Iruela-Arispe ML, Segura T. The phosphorylation of vascular endothelial growth factor receptor-2 (VEGFR-2) by engineered surfaces with electrostatically or covalently immobilized VEGF. Biomaterials. 30: 4618-28. PMID 19540581 DOI: 10.1016/J.Biomaterials.2009.05.030  0.458
2009 Speck NA, Iruela-Arispe ML. Conditional Cre/LoxP strategies for the study of hematopoietic stem cell formation. Blood Cells, Molecules & Diseases. 43: 6-11. PMID 19250847 DOI: 10.1016/J.Bcmd.2009.01.010  0.351
2009 Iruela-Arispe ML, Davis GE. Cellular and molecular mechanisms of vascular lumen formation. Developmental Cell. 16: 222-31. PMID 19217424 DOI: 10.1016/J.Devcel.2009.01.013  0.481
2009 Rodríguez-Manzaneque JC, Carpizo D, Plaza-Calonge Mdel C, Torres-Collado AX, Thai SN, Simons M, Horowitz A, Iruela-Arispe ML. Cleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion. The International Journal of Biochemistry & Cell Biology. 41: 800-10. PMID 18775505 DOI: 10.1016/J.Biocel.2008.08.014  0.381
2008 Zovein AC, Hofmann JJ, Lynch M, French WJ, Turlo KA, Yang Y, Becker MS, Zanetta L, Dejana E, Gasson JC, Tallquist MD, Iruela-Arispe ML. Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells Cell Stem Cell. 3: 625-636. PMID 19041779 DOI: 10.1016/J.Stem.2008.09.018  0.432
2008 Iruela-Arispe ML. Regulation of thrombospondin1 by extracellular proteases. Current Drug Targets. 9: 863-8. PMID 18855620 DOI: 10.2174/138945008785909365  0.318
2008 Suárez Y, Fernández-Hernando C, Yu J, Gerber SA, Harrison KD, Pober JS, Iruela-Arispe ML, Merkenschlager M, Sessa WC. Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 14082-7. PMID 18779589 DOI: 10.1073/Pnas.0804597105  0.369
2008 Guo W, Lasky JL, Chang CJ, Mosessian S, Lewis X, Xiao Y, Yeh JE, Chen JY, Iruela-Arispe ML, Varella-Garcia M, Wu H. Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. Nature. 453: 529-33. PMID 18463637 DOI: 10.1038/Nature06933  0.305
2008 Stankunas K, Hang CT, Tsun ZY, Chen H, Lee NV, Wu JI, Shang C, Bayle JH, Shou W, Iruela-Arispe ML, Chang CP. Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Developmental Cell. 14: 298-311. PMID 18267097 DOI: 10.1016/J.Devcel.2007.11.018  0.302
2007 Lee S, Chen TT, Barber CL, Jordan MC, Murdock J, Desai S, Ferrara N, Nagy A, Roos KP, Iruela-Arispe ML. Autocrine VEGF signaling is required for vascular homeostasis. Cell. 130: 691-703. PMID 17719546 DOI: 10.1016/J.Cell.2007.06.054  0.504
2007 Hofmann JJ, Iruela-Arispe ML. Notch signaling in blood vessels: who is talking to whom about what? Circulation Research. 100: 1556-68. PMID 17556669 DOI: 10.1161/01.Res.0000266408.42939.E4  0.426
2007 Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 445: 776-80. PMID 17259973 DOI: 10.1038/Nature05571  0.516
2007 Yang LV, Radu CG, Roy M, Lee S, McLaughlin J, Teitell MA, Iruela-Arispe ML, Witte ON. Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor. Molecular and Cellular Biology. 27: 1334-47. PMID 17145776 DOI: 10.1128/Mcb.01909-06  0.383
2007 Iruela-Arispe ML. Signaling pathways that regulate vascular lumen formation The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A133-D  0.408
2006 Monvoisin A, Alva JA, Hofmann JJ, Zovein AC, Lane TF, Iruela-Arispe ML. VE-cadherin-CreERT2 transgenic mouse: a model for inducible recombination in the endothelium. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 3413-22. PMID 17072878 DOI: 10.1002/Dvdy.20982  0.462
2006 Zovein AC, Iruela-Arispe ML. My O'Myeloid, a tale of two lineages. Proceedings of the National Academy of Sciences of the United States of America. 103: 12959-60. PMID 16924095 DOI: 10.1073/Pnas.0606018103  0.361
2006 Iruela-Arispe ML. When it comes to blocking lymphatics, it is all a question of time. The American Journal of Pathology. 169: 347-50. PMID 16877337 DOI: 10.2353/Ajpath.2006.060427  0.426
2006 Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS. Proteolytic cleavage of versican during cardiac cushion morphogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2238-47. PMID 16691565 DOI: 10.1002/Dvdy.20838  0.353
2006 Barber CL, Iruela-Arispe ML. The ever-elusive endothelial progenitor cell: identities, functions and clinical implications. Pediatric Research. 59: 26R-32R. PMID 16549545 DOI: 10.1203/01.Pdr.0000203553.46471.18  0.476
2006 Alva JA, Zovein AC, Monvoisin A, Murphy T, Salazar A, Harvey NL, Carmeliet P, Iruela-Arispe ML. VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 759-67. PMID 16450386 DOI: 10.1002/Dvdy.20643  0.425
2005 Lee NV, Rodriguez-Manzaneque JC, Thai SN, Twal WO, Luque A, Lyons KM, Argraves WS, Iruela-Arispe ML. Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. The Journal of Biological Chemistry. 280: 34796-804. PMID 16061471 DOI: 10.1074/Jbc.M506980200  0.325
2005 Lee S, Jilani SM, Nikolova GV, Carpizo D, Iruela-Arispe ML. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. The Journal of Cell Biology. 169: 681-91. PMID 15911882 DOI: 10.1083/Jcb.200409115  0.446
2005 Krampert M, Kuenzle S, Thai SN, Lee N, Iruela-Arispe ML, Werner S. ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells. The Journal of Biological Chemistry. 280: 23844-52. PMID 15843381 DOI: 10.1074/Jbc.M412212200  0.385
2004 Alva JA, Iruela-Arispe ML. Notch signaling in vascular morphogenesis. Current Opinion in Hematology. 11: 278-83. PMID 15314528 DOI: 10.1097/01.Moh.0000130309.44976.Ad  0.477
2004 Iruela-Arispe ML, Luque A, Lee N. Thrombospondin modules and angiogenesis. The International Journal of Biochemistry & Cell Biology. 36: 1070-8. PMID 15094121 DOI: 10.1016/J.Biocel.2004.01.025  0.491
2004 Calzada MJ, Zhou L, Sipes JM, Zhang J, Krutzsch HC, Iruela-Arispe ML, Annis DS, Mosher DF, Roberts DD. Alpha4beta1 integrin mediates selective endothelial cell responses to thrombospondins 1 and 2 in vitro and modulates angiogenesis in vivo. Circulation Research. 94: 462-70. PMID 14699013 DOI: 10.1161/01.Res.0000115555.05668.93  0.495
2004 Lee S, Jilani S, Nikolova GV, Carpizo D, Yokoyama E, Iruela-Arispe ML. Proteolytic Processing Of Vegf-A Affects Biological Activity Without Altering Vegfr-2 Phosphorylation Levels Cardiovascular Pathology. 13: 9. DOI: 10.1016/J.Carpath.2004.03.020  0.423
2003 Iruela-Arispe ML, Carpizo D, Luque A. ADAMTS1: a matrix metalloprotease with angioinhibitory properties. Annals of the New York Academy of Sciences. 995: 183-90. PMID 12814950 DOI: 10.1111/J.1749-6632.2003.Tb03221.X  0.333
2003 Luque A, Carpizo DR, Iruela-Arispe ML. ADAMTS1/METH1 inhibits endothelial cell proliferation by direct binding and sequestration of VEGF165. The Journal of Biological Chemistry. 278: 23656-65. PMID 12716911 DOI: 10.1074/Jbc.M212964200  0.456
2003 Jilani SM, Murphy TJ, Thai SN, Eichmann A, Alva JA, Iruela-Arispe ML. Selective binding of lectins to embryonic chicken vasculature. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 51: 597-604. PMID 12704207 DOI: 10.1177/002215540305100505  0.365
2002 Gaspar J, Thai S, Voland C, Dube A, Libermann TA, Iruela-Arispe ML, Oettgen P. Opposing functions of the Ets factors NERF and ELF-1 during chicken blood vessel development. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1106-12. PMID 12117724 DOI: 10.1161/01.Atv.0000023427.92642.Cd  0.356
2002 Thai SN, Iruela-Arispe ML. Expression of ADAMTS1 during murine development. Mechanisms of Development. 115: 181-5. PMID 12049787 DOI: 10.1016/S0925-4773(02)00115-6  0.302
2001 Rodriguez-Manzaneque JC, Lane TF, Ortega MA, Hynes RO, Lawler J, Iruela-Arispe ML. Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proceedings of the National Academy of Sciences of the United States of America. 98: 12485-90. PMID 11606713 DOI: 10.1073/Pnas.171460498  0.396
2001 Villa N, Walker L, Lindsell CE, Gasson J, Iruela-Arispe ML, Weinmaster G. Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels Mechanisms of Development. 108: 161-164. PMID 11578869 DOI: 10.1016/S0925-4773(01)00469-5  0.469
2001 Graubert MD, Ortega MA, Kessel B, Mortola JF, Iruela-Arispe ML. Vascular repair after menstruation involves regulation of vascular endothelial growth factor-receptor phosphorylation by sFLT-1. American Journal of Pathology. 158: 1399-1410. PMID 11290558 DOI: 10.1016/S0002-9440(10)64091-6  0.467
2000 Carpizo D, Iruela-Arispe ML. Endogenous regulators of angiogenesis : emphasis on proteins with thrombospondin : type I motifs Cancer and Metastasis Reviews. 19: 159-165. PMID 11191055 DOI: 10.1023/A:1026570331022  0.446
2000 Rodríguez-Manzaneque JC, Graubert M, Iruela-Arispe ML. Endothelial cell dysfunction following prolonged activation of progesterone receptor Human Reproduction. 15: 39-47. PMID 11041220 DOI: 10.1093/Humrep/15.Suppl_3.39  0.332
2000 Chandrasekaran L, He C, Al-Barazi H, Krutzsch HC, Iruela-Arispe ML, Roberts DD. Cell Contact–dependent Activation of α3β1 Integrin Modulates Endothelial Cell Responses to Thrombospondin-1 Molecular Biology of the Cell. 11: 2885-2900. PMID 10982388 DOI: 10.1091/Mbc.11.9.2885  0.473
2000 Pal S, Iruela-Arispe ML, Harvey VS, Zeng H, Nagy JA, Dvorak HF, Mukhopadhyay D. Retinoic acid selectively inhibits the vascular permeabilizing effect of VPF/VEGF, an early step in the angiogenic cascade. Microvascular Research. 60: 112-120. PMID 10964585 DOI: 10.1006/Mvre.2000.2246  0.425
2000 Pepper MS, Baetens D, Mandriota SJ, Sanza CD, Oikemus S, Lane TF, Soriano JV, Montesano R, Iruela-Arispe ML. Regulation of VEGF and VEGF receptor expression in the rodent mammary gland during pregnancy, lactation, and involution Developmental Dynamics. 218: 507-524. PMID 10878616 DOI: 10.1002/1097-0177(200007)218:3<507::Aid-Dvdy1012>3.0.Co;2-5  0.487
2000 Lee SW, Reimer CL, Fang L, Iruela-Arispe ML, Aaronson SA. Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression. Molecular and Cellular Biology. 20: 1723-32. PMID 10669749 DOI: 10.1128/Mcb.20.5.1723-1732.2000  0.307
2000 Iruela-Arispe ML, Vázquez F, Ortega MA. Antiangiogenic domains shared by thrombospondins and metallospondins, a new family of angiogenic inhibitors. Annals of the New York Academy of Sciences. 886: 58-66. PMID 10667203 DOI: 10.1111/j.1749-6632.1999.tb09400.x  0.321
1999 Iruela-Arispe ML, Lombardo M, Krutzsch HC, Lawler J, Roberts DD. Inhibition of Angiogenesis by Thrombospondin-1 Is Mediated by 2 Independent Regions Within the Type 1 Repeats Circulation. 100: 1423-1431. PMID 10500044 DOI: 10.1161/01.Cir.100.13.1423  0.433
1999 Iruela-Arispe ML, Rodriguez-Manzaneque JC, Abu-Jawdeh G. Endometrial endothelial cells express estrogen and progesterone receptors and exhibit a tissue specific response to angiogenic growth factors. Microcirculation (New York, N.Y. : 1994). 6: 127-40. PMID 10466115  0.36
1999 Vázquez F, Hastings G, Ortega MA, Lane TF, Oikemus S, Lombardo M, Iruela-Arispe ML. METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity. The Journal of Biological Chemistry. 274: 23349-57. PMID 10438512 DOI: 10.1074/Jbc.274.33.23349  0.426
1999 Brown LF, Guidi AJ, Schnitt SJ, Van De Water L, Iruela-Arispe ML, Yeo TK, Tognazzi K, Dvorak HF. Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 1041-56. PMID 10353737  0.346
1999 Vázquez F, Rodríguez-Manzaneque JC, Lydon JP, Edwards DP, O'Malley BW, Iruela-Arispe ML. Progesterone regulates proliferation of endothelial cells. The Journal of Biological Chemistry. 274: 2185-92. PMID 9890981 DOI: 10.1074/Jbc.274.4.2185  0.461
1999 Iruela-Arispe ML, Rodriguez-Manzaneque JC, Abu-Jawdeh G. Endometrial Endothelial Cells Express Estrogen and Progesterone Receptors and Exhibit a Tissue Specific Response to Angiogenic Growth Factors Microcirculation. 6: 127-140. DOI: 10.1111/J.1549-8719.1999.Tb00095.X  0.445
1997 Lee SH, Hungerford JE, Little CD, Iruela-Arispe ML. Proliferation and differentiation of smooth muscle cell precursors occurs simultaneously during the development of the vessel wall. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 209: 342-52. PMID 9264258 DOI: 10.1002/(Sici)1097-0177(199708)209:4<342::Aid-Aja2>3.0.Co;2-I  0.372
1997 Iruela-Arispe ML, Dvorak HF. Angiogenesis: a dynamic balance of stimulators and inhibitors. Thrombosis and Haemostasis. 78: 672-7. PMID 9198237  0.356
1997 Iruela-Arispe ML. Normal placentation: a tale that requires an epithelial-to-endothelial conversion. The Journal of Clinical Investigation. 99: 2057-8. PMID 9151773 DOI: 10.1172/JCI119374  0.338
1997 Brown LF, Detmar M, Tognazzi K, Abu-Jawdeh G, Iruela-Arispe ML. Uterine smooth muscle cells express functional receptors (flt-1 and KDR) for vascular permeability factor/vascular endothelial growth factor. Laboratory Investigation; a Journal of Technical Methods and Pathology. 76: 245-55. PMID 9042161  0.356
1997 Iruela-Arispe ML, Vernon RB, Wu H, Jaenisch R, Sage EH. Type I collagen-deficient Mov-13 mice do not retain SPARC in the extracellular matrix: implications for fibroblast function. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 207: 171-83. PMID 8906420 DOI: 10.1002/(Sici)1097-0177(199610)207:2<171::Aid-Aja5>3.0.Co;2-E  0.342
1996 Iruela-Arispe ML, Porter P, Bornstein P, Sage EH. Thrombospondin-1, an inhibitor of angiogenesis, is regulated by progesterone in the human endometrium. The Journal of Clinical Investigation. 97: 403-12. PMID 8567961 DOI: 10.1172/Jci118429  0.303
1995 Vernon RB, Lara SL, Drake CJ, Iruela-Arispe ML, Angello JC, Little CD, Wight TN, Sage EH. Organized type I collagen influences endothelial patterns during "spontaneous angiogenesis in vitro": planar cultures as models of vascular development. In Vitro Cellular & Developmental Biology. Animal. 31: 120-31. PMID 7537585 DOI: 10.1007/Bf02633972  0.46
1993 Iruela-Arispe ML, Liska DJ, Sage EH, Bornstein P. Differential expression of thrombospondin 1, 2, and 3 during murine development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 197: 40-56. PMID 8400410 DOI: 10.1002/Aja.1001970105  0.358
1993 Iruela-Arispe ML, Sage EH. Endothelial cells exhibiting angiogenesis in vitro proliferate in response to TGF-beta 1. Journal of Cellular Biochemistry. 52: 414-30. PMID 7693728 DOI: 10.1002/Jcb.240520406  0.368
1993 Järveläinen HT, Iruela-Arispe ML, Kinsella MG, Sandell LJ, Sage EH, Wight TN. Expression of decorin by sprouting bovine aortic endothelial cells exhibiting angiogenesis in vitro. Experimental Cell Research. 203: 395-401. PMID 1281110 DOI: 10.1016/0014-4827(92)90013-X  0.397
1991 Iruela-Arispe ML, Diglio CA, Sage EH. Modulation of extracellular matrix proteins by endothelial cells undergoing angiogenesis in vitro. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 11: 805-15. PMID 1712229 DOI: 10.1161/01.ATV.11.4.805  0.348
1991 Iruela-Arispe ML, Bornstein P, Sage H. Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proceedings of the National Academy of Sciences of the United States of America. 88: 5026-30. PMID 1711216 DOI: 10.1073/Pnas.88.11.5026  0.341
1991 Iruela-Arispe ML, Hasselaar P, Sage H. Differential expression of extracellular proteins is correlated with angiogenesis in vitro. Laboratory Investigation; a Journal of Technical Methods and Pathology. 64: 174-86. PMID 1705300  0.329
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