| Year |
Citation |
Score |
| 2024 |
Kumar S, Bajpai P, Joyce C, Kabra SK, Lodha R, Burton DR, Briney B, Luthra K. B cell repertoire sequencing of HIV-1 pediatric elite-neutralizers identifies multiple broadly neutralizing antibody clonotypes. Frontiers in Immunology. 15: 1272493. PMID 38433846 DOI: 10.3389/fimmu.2024.1272493 |
0.4 |
|
| 2024 |
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, ... ... Burton DR, et al. Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Biorxiv : the Preprint Server For Biology. PMID 38405899 DOI: 10.1101/2024.02.13.580058 |
0.501 |
|
| 2024 |
Khalek IS, Senji Laxme RR, Nguyen YTK, Khochare S, Patel RN, Woehl J, Smith JM, Saye-Francisco K, Kim Y, Misson Mindrebo L, Tran Q, Kędzior M, Boré E, Limbo O, Verma M, ... ... Burton DR, et al. Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins. Science Translational Medicine. 16: eadk1867. PMID 38381847 DOI: 10.1126/scitranslmed.adk1867 |
0.382 |
|
| 2024 |
Grunst MW, Gil HM, Grandea AG, Snow BJ, Andrabi R, Nedellec R, Burton I, Clark NM, Janaka SK, Keles NK, Moriarty RV, Weiler AM, Capuano S, Fennessey CM, Friedrich TC, ... ... Burton DR, et al. Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge. Plos Pathogens. 20: e1011819. PMID 38252675 DOI: 10.1371/journal.ppat.1011819 |
0.447 |
|
| 2023 |
Phung I, Rodrigues KA, Marina-Zárate E, Maiorino L, Pahar B, Lee WH, Melo M, Kaur A, Allers C, Fahlberg M, Grasperge BF, Dufour JP, Schiro F, Aye PP, Lopez PG, ... ... Burton DR, et al. A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nature Communications. 14: 7107. PMID 37925510 DOI: 10.1038/s41467-023-42923-x |
0.436 |
|
| 2023 |
Stab V, Stahl-Hennig C, Ensser A, Richel E, Fraedrich K, Sauermann U, Tippler B, Klein F, Burton DR, Tenbusch M, Überla K. HIV-1 neutralizing antibodies provide sterilizing immunity by blocking infection of the first cells. Cell Reports. Medicine. 4: 101201. PMID 37804829 DOI: 10.1016/j.xcrm.2023.101201 |
0.448 |
|
| 2023 |
Huang R, Warner Jenkins G, Kim Y, Stanfield RL, Singh A, Martinez-Yamout M, Kroon GJ, Torres JL, Jackson AM, Kelley A, Shaabani N, Zeng B, Bacica M, Chen W, Warner C, ... ... Burton DR, et al. The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303455120. PMID 37722054 DOI: 10.1073/pnas.2303455120 |
0.35 |
|
| 2023 |
Zhao F, Yuan M, Keating C, Shaabani N, Limbo O, Joyce C, Woehl J, Barman S, Burns A, Tran Q, Zhu X, Ricciardi M, Peng L, Smith J, Huang D, ... ... Burton DR, et al. Broadening a SARS-CoV-1-neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution. Science Signaling. 16: eabk3516. PMID 37582161 DOI: 10.1126/scisignal.abk3516 |
0.387 |
|
| 2023 |
Cottrell CA, Pratap PP, Cirelli KM, Carnathan DG, Enemuo CA, Antanasijevic A, Ozorowski G, Sewall LM, Gao H, Greene KM, Allen JD, Ngo JT, Choe Y, Nogal B, Silva M, ... ... Burton DR, et al. Focusing antibody responses to the fusion peptide in rhesus macaques. Biorxiv : the Preprint Server For Biology. PMID 37425865 DOI: 10.1101/2023.06.26.545779 |
0.474 |
|
| 2023 |
Joyce C, Murrell S, Murrell B, Omorodion O, Ver LS, Carrico N, Bastidas R, Nedellec R, Bick M, Woehl J, Zhao F, Burns A, Barman S, Appel M, Ramos A, ... ... Burton DR, et al. Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies. Plos Pathogens. 19: e1011416. PMID 37384622 DOI: 10.1371/journal.ppat.1011416 |
0.497 |
|
| 2023 |
Misson Mindrebo L, Liu H, Ozorowski G, Tran Q, Woehl J, Khalek I, Smith JM, Barman S, Zhao F, Keating C, Limbo O, Verma M, Liu J, Stanfield RL, Zhu X, ... ... Burton DR, et al. Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216612120. PMID 37276407 DOI: 10.1073/pnas.2216612120 |
0.365 |
|
| 2023 |
Kaku CI, Starr TN, Zhou P, Dugan HL, Khalifé P, Song G, Champney ER, Mielcarz DW, Geoghegan JC, Burton DR, Andrabi R, Bloom JD, Walker LM. Evolution of antibody immunity following Omicron BA.1 breakthrough infection. Nature Communications. 14: 2751. PMID 37173311 DOI: 10.1038/s41467-023-38345-4 |
0.379 |
|
| 2023 |
Song G, Yuan M, Liu H, Capozzola T, Lin RN, Torres JL, He WT, Musharrafieh R, Dueker K, Zhou P, Callaghan S, Mishra N, Yong P, Anzanello F, Avillion G, ... ... Burton DR, et al. Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift. Biorxiv : the Preprint Server For Biology. PMID 37162858 DOI: 10.1101/2023.04.26.538488 |
0.347 |
|
| 2023 |
Burton DR. Antiviral neutralizing antibodies: from in vitro to in vivo activity. Nature Reviews. Immunology. 1-15. PMID 37069260 DOI: 10.1038/s41577-023-00858-w |
0.45 |
|
| 2023 |
Hurtado J, Rogers TF, Jaffe DB, Adams BA, Bangaru S, Garcia E, Capozzola T, Messmer T, Sharma P, Song G, Beutler N, He W, Dueker K, Musharrafieh R, Stubbington MJT, ... Burton DR, et al. Deep repertoire mining uncovers ultra-broad coronavirus neutralizing antibodies targeting multiple spike epitopes. Biorxiv : the Preprint Server For Biology. PMID 37034676 DOI: 10.1101/2023.03.28.534602 |
0.436 |
|
| 2023 |
Ricciardi MJ, Rust LN, Pedreño-Lopez N, Yusova S, Biswas S, Webb GM, Gonzalez-Nieto L, Voigt TB, Louw JJ, Laurino FD, DiBello JR, Raué HP, Barber-Axthelm AM, Chun K, Uttke S, ... ... Burton DR, et al. Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection. Science Translational Medicine. 15: eade5795. PMID 36989376 DOI: 10.1126/scitranslmed.ade5795 |
0.373 |
|
| 2023 |
Allen JD, Ivory DP, Song SG, He WT, Capozzola T, Yong P, Burton DR, Andrabi R, Crispin M. The diversity of the glycan shield of sarbecoviruses related to SARS-CoV-2. Cell Reports. 42: 112307. PMID 36972173 DOI: 10.1016/j.celrep.2023.112307 |
0.31 |
|
| 2023 |
Hurtado J, Flynn C, Lee JH, Salcedo EC, Cottrell CA, Skog PD, Burton DR, Nemazee D, Schief WR, Landais E, Sok D, Briney B. Efficient isolation of rare B cells using next-generation antigen barcoding. Frontiers in Cellular and Infection Microbiology. 12: 962945. PMID 36968243 DOI: 10.3389/fcimb.2022.962945 |
0.338 |
|
| 2023 |
Zhou P, Song G, Liu H, Yuan M, He WT, Beutler N, Zhu X, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, ... ... Burton DR, et al. Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity. PMID 36889306 DOI: 10.1016/j.immuni.2023.02.005 |
0.44 |
|
| 2023 |
Rosato PC, Lotfi-Emran S, Joag V, Wijeyesinghe S, Quarnstrom CF, Degefu HN, Nedellec R, Schenkel JM, Beura LK, Hangartner L, Burton DR, Masopust D. Tissue resident memory T cells trigger rapid exudation and local antibody accumulation. Mucosal Immunology. PMID 36657662 DOI: 10.1016/j.mucimm.2022.11.004 |
0.334 |
|
| 2023 |
Bibollet-Ruche F, Russell RM, Ding W, Liu W, Li Y, Wagh K, Wrapp D, Habib R, Skelly AN, Roark RS, Sherrill-Mix S, Wang S, Rando J, Lindemuth E, Cruickshank K, ... ... Burton DR, et al. A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies. Mbio. e0337022. PMID 36629414 DOI: 10.1128/mbio.03370-22 |
0.451 |
|
| 2022 |
Frankel AE, Capozzola T, Andrabi R, Ahn C, Zhou P, He WT, Burton DR. The Effects of an mRNA Covid-19 Vaccine Booster on Immune Responses in Cancer-Bearing Veterans. Medical Research Archives. 10. PMID 36405515 DOI: 10.18103/mra.v10i7.2932 |
0.394 |
|
| 2022 |
van Schooten J, Schorcht A, Farokhi E, Umotoy JC, Gao H, van den Kerkhof TLGM, Dorning J, Rijkhold Meesters TG, van der Woude P, Burger JA, Bijl T, Ghalaiyini R, Torrents de la Peña A, Turner HL, Labranche CC, ... ... Burton DR, et al. Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer. Plos Pathogens. 18: e1010945. PMID 36395347 DOI: 10.1371/journal.ppat.1010945 |
0.536 |
|
| 2022 |
Prévost J, Anand SP, Rajashekar JK, Zhu L, Richard J, Goyette G, Medjahed H, Gendron-Lepage G, Chen HC, Chen Y, Horwitz JA, Grunst MW, Zolla-Pazner S, Haynes BF, Burton DR, et al. HIV-1 Vpu restricts Fc-mediated effector functions in vivo. Cell Reports. 41: 111624. PMID 36351384 DOI: 10.1016/j.celrep.2022.111624 |
0.418 |
|
| 2022 |
Kaku CI, Starr TN, Zhou P, Dugan HL, Khalifé P, Song G, Champney ER, Mielcarz DW, Geoghegan JC, Burton DR, Andrabi R, Bloom JD, Walker LM. Evolution of antibody immunity following Omicron BA.1 breakthrough infection. Biorxiv : the Preprint Server For Biology. PMID 36172124 DOI: 10.1101/2022.09.21.508922 |
0.381 |
|
| 2022 |
Lee JH, Sutton HJ, Cottrell CA, Phung I, Ozorowski G, Sewall LM, Nedellec R, Nakao C, Silva M, Richey ST, Torre JL, Lee WH, Georgeson E, Kubitz M, Hodges S, ... ... Burton DR, et al. Long-primed germinal centres with enduring affinity maturation and clonal migration. Nature. PMID 36131022 DOI: 10.1038/s41586-022-05216-9 |
0.401 |
|
| 2022 |
Zhao F, Berndsen ZT, Pedreño-Lopez N, Burns A, Allen JD, Barman S, Lee WH, Chakraborty S, Gnanakaran S, Sewall LM, Ozorowski G, Limbo O, Song G, Yong P, Callaghan S, ... ... Burton DR, et al. Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nature Communications. 13: 5236. PMID 36068229 DOI: 10.1038/s41467-022-32783-2 |
0.469 |
|
| 2022 |
Allen JD, Ivory D, Song SG, He WT, Capozzola T, Yong P, Burton DR, Andrabi R, Crispin M. The diversity of the glycan shield of sarbecoviruses closely related to SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 36052375 DOI: 10.1101/2022.08.24.505118 |
0.355 |
|
| 2022 |
Tas JMJ, Koo JH, Lin YC, Xie Z, Steichen JM, Jackson AM, Hauser BM, Wang X, Cottrell CA, Torres JL, Warner JE, Kirsch KH, Weldon SR, Groschel B, Nogal B, ... ... Burton DR, et al. Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses. Immunity. PMID 35987201 DOI: 10.1016/j.immuni.2022.07.020 |
0.438 |
|
| 2022 |
Zhao F, Keating C, Ozorowski G, Shaabani N, Francino-Urdaniz IM, Barman S, Limbo O, Burns A, Zhou P, Ricciardi MJ, Woehl J, Tran Q, Turner HL, Peng L, Huang D, ... ... Burton DR, et al. TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways. Iscience. 104914. PMID 35971553 DOI: 10.1016/j.isci.2022.104914 |
0.453 |
|
| 2022 |
He WT, Yuan M, Callaghan S, Musharrafieh R, Song G, Silva M, Beutler N, Lee WH, Yong P, Torres JL, Melo M, Zhou P, Zhao F, Zhu X, Peng L, ... ... Burton DR, et al. Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science Translational Medicine. 14: eabl9605. PMID 35947674 DOI: 10.1126/scitranslmed.abl9605 |
0.468 |
|
| 2022 |
van Schooten J, Farokhi E, Schorcht A, van den Kerkhof TLGM, Gao H, van der Woude P, Burger JA, Meesters TGR, Bijl T, Ghalaiyini R, Turner HL, Dorning J, van Schaik BDC, van Kampen AHC, Labranche CC, ... ... Burton DR, et al. Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nature Communications. 13: 4515. PMID 35922441 DOI: 10.1038/s41467-022-32208-0 |
0.473 |
|
| 2022 |
Liu H, Kaku CI, Song G, Yuan M, Andrabi R, Burton DR, Walker LM, Wilson IA. Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron. Communications Biology. 5: 766. PMID 35906394 DOI: 10.1038/s42003-022-03700-6 |
0.433 |
|
| 2022 |
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, ... ... Burton DR, et al. A broad and potent neutralization epitope in SARS-related coronaviruses. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205784119. PMID 35767670 DOI: 10.1073/pnas.2205784119 |
0.403 |
|
| 2022 |
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, ... ... Burton DR, et al. Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses. Nature Immunology. 23: 960-970. PMID 35654851 DOI: 10.1038/s41590-022-01222-1 |
0.4 |
|
| 2022 |
Ferrara F, Erasmus MF, D'Angelo S, Leal-Lopes C, Teixeira AA, Choudhary A, Honnen W, Calianese D, Huang D, Peng L, Voss JE, Nemazee D, Burton DR, Pinter A, Bradbury ARM. Author Correction: A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies. Nature Communications. 13: 2097. PMID 35414071 DOI: 10.1038/s41467-022-29876-3 |
0.353 |
|
| 2022 |
Hurlburt NK, Homad LJ, Sinha I, Jennewein MF, MacCamy AJ, Wan YH, Boonyaratanakornkit J, Sholukh AM, Jackson AM, Zhou P, Burton DR, Andrabi R, Ozorowski G, Ward AB, Stamatatos L, et al. Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit. Communications Biology. 5: 342. PMID 35411021 DOI: 10.1038/s42003-022-03262-7 |
0.358 |
|
| 2022 |
Beutler N, Pholcharee T, Oyen D, Flores-Garcia Y, MacGill RS, Garcia E, Calla J, Parren M, Yang L, Volkmuth W, Locke E, Regules JA, Dutta S, Emerling D, Early AM, ... ... Burton DR, et al. A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum. Plos Pathogens. 18: e1010409. PMID 35344575 DOI: 10.1371/journal.ppat.1010409 |
0.4 |
|
| 2022 |
Yuan M, Zhu X, He WT, Zhou P, Kaku CI, Capozzola T, Zhu CY, Yu X, Liu H, Yu W, Hua Y, Tien H, Peng L, Song G, Cottrell CA, ... ... Burton DR, et al. A broad and potent neutralization epitope in SARS-related coronaviruses. Biorxiv : the Preprint Server For Biology. PMID 35313576 DOI: 10.1101/2022.03.13.484037 |
0.41 |
|
| 2022 |
Zhou P, Song G, He WT, Beutler N, Tse LV, Martinez DR, Schäfer A, Anzanello F, Yong P, Peng L, Dueker K, Musharrafieh R, Callaghan S, Capozzola T, Yuan M, ... ... Burton DR, et al. Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease. Biorxiv : the Preprint Server For Biology. PMID 35291291 DOI: 10.1101/2022.03.04.479488 |
0.416 |
|
| 2022 |
He WT, Musharrafieh R, Song G, Dueker K, Tse LV, Martinez DR, Schäfer A, Callaghan S, Yong P, Beutler N, Torres JL, Volk RM, Zhou P, Yuan M, Liu H, ... ... Burton DR, et al. Targeted isolation of panels of diverse human protective broadly neutralizing antibodies against SARS-like viruses. Biorxiv : the Preprint Server For Biology. PMID 35169804 DOI: 10.1101/2021.09.08.459480 |
0.42 |
|
| 2022 |
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, ... ... Burton DR, et al. A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection. Science Translational Medicine. eabi9215. PMID 35133175 DOI: 10.1126/scitranslmed.abi9215 |
0.357 |
|
| 2022 |
Ferrara F, Erasmus MF, D'Angelo S, Leal-Lopes C, Teixeira AA, Choudhary A, Honnen W, Calianese D, Huang D, Peng L, Voss JE, Nemazee D, Burton DR, Pinter A, Bradbury ARM. A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies. Nature Communications. 13: 462. PMID 35075126 DOI: 10.1038/s41467-021-27799-z |
0.391 |
|
| 2021 |
van Schooten J, van Haaren MM, Li H, McCoy LE, Havenar-Daughton C, Cottrell CA, Burger JA, van der Woude P, Helgers LC, Tomris I, Labranche CC, Montefiori DC, Ward AB, Burton DR, Moore JP, et al. Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates. Plos Pathogens. 17: e1009736. PMID 34432859 DOI: 10.1371/journal.ppat.1009736 |
0.481 |
|
| 2021 |
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, ... ... Burton DR, et al. Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM. Nature Communications. 12: 4817. PMID 34376662 DOI: 10.1038/s41467-021-25087-4 |
0.496 |
|
| 2021 |
Turner HL, Andrabi R, Cottrell CA, Richey ST, Song G, Callaghan S, Anzanello F, Moyer TJ, Abraham W, Melo M, Silva M, Scaringi N, Rakasz EG, Sattentau QJ, Irvine DJ, ... Burton DR, et al. Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization. Science Advances. 7. PMID 34321200 DOI: 10.1126/sciadv.abh2791 |
0.546 |
|
| 2021 |
Anand SP, Ding S, Tolbert WD, Prévost J, Richard J, Gil HM, Gendron-Lepage G, Cheung WF, Wang H, Pastora R, Saxena H, Wakarchuk W, Medjahed H, Wines BD, Hogarth PM, ... ... Burton DR, et al. Enhanced ability of plant-derived PGT121 glycovariants to eliminate HIV-1-infected cells. Journal of Virology. JVI0079621. PMID 34232070 DOI: 10.1128/JVI.00796-21 |
0.39 |
|
| 2021 |
Rissanen I, Krumm SA, Stass R, Whitaker A, Voss JE, Bruce EA, Rothenberger S, Kunz S, Burton DR, Huiskonen JT, Botten JW, Bowden TA, Doores KJ. Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen. Mbio. e0253120. PMID 34225492 DOI: 10.1128/mBio.02531-20 |
0.443 |
|
| 2021 |
Huang D, Tran JT, Peng L, Yang L, Suhandynata RT, Hoffman MA, Zhao F, Song G, He WT, Limbo O, Callaghan S, Landais E, Andrabi R, Sok D, Jardine JG, ... Burton DR, et al. A Rapid Assay for SARS-CoV-2 Neutralizing Antibodies That Is Insensitive to Antiretroviral Drugs. Journal of Immunology (Baltimore, Md. : 1950). PMID 34183368 DOI: 10.4049/jimmunol.2100155 |
0.381 |
|
| 2021 |
Yuan M, Huang D, Lee CD, Wu NC, Jackson AM, Zhu X, Liu H, Peng L, van Gils MJ, Sanders RW, Burton DR, Reincke SM, Prüss H, Kreye J, Nemazee D, et al. Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science (New York, N.Y.). PMID 34016740 DOI: 10.1126/science.abh1139 |
0.371 |
|
| 2021 |
Song G, He WT, Callaghan S, Anzanello F, Huang D, Ricketts J, Torres JL, Beutler N, Peng L, Vargas S, Cassell J, Parren M, Yang L, Ignacio C, Smith DM, ... ... Burton DR, et al. Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection. Nature Communications. 12: 2938. PMID 34011939 DOI: 10.1038/s41467-021-23074-3 |
0.332 |
|
| 2021 |
Zhou X, Ma F, Xie J, Yuan M, Li Y, Shaabani N, Zhao F, Huang D, Wu NC, Lee CD, Liu H, Li J, Chen Z, Hong Y, Liu WH, ... ... Burton DR, et al. Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2. Cell Reports. 109109. PMID 33932326 DOI: 10.1016/j.celrep.2021.109109 |
0.398 |
|
| 2021 |
Liu H, Yuan M, Huang D, Bangaru S, Zhao F, Lee CD, Peng L, Barman S, Zhu X, Nemazee D, Burton DR, van Gils MJ, Sanders RW, Kornau HC, Reincke SM, et al. A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection. Cell Host & Microbe. PMID 33894127 DOI: 10.1016/j.chom.2021.04.005 |
0.436 |
|
| 2021 |
Zhou P, Yuan M, Song G, Beutler N, Shaabani N, Huang D, He WT, Zhu X, Callaghan S, Yong P, Anzanello F, Peng L, Ricketts J, Parren M, Garcia E, ... ... Burton DR, et al. A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes. Biorxiv : the Preprint Server For Biology. PMID 33821273 DOI: 10.1101/2021.03.30.437769 |
0.347 |
|
| 2021 |
Hangartner L, Beauparlant D, Rakasz E, Nedellec R, Hozé N, McKenney K, Martins MA, Seabright GE, Allen JD, Weiler AM, Friedrich TC, Regoes RR, Crispin M, Burton DR. Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates. Science Translational Medicine. 13. PMID 33731434 DOI: 10.1126/scitranslmed.abe3349 |
0.519 |
|
| 2021 |
Conti S, Kaczorowski KJ, Song G, Porter K, Andrabi R, Burton DR, Chakraborty AK, Karplus M. Design of immunogens to elicit broadly neutralizing antibodies against HIV targeting the CD4 binding site. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33637649 DOI: 10.1073/pnas.2018338118 |
0.562 |
|
| 2021 |
Turner HL, Andrabi R, Cottrell CA, Richey ST, Song G, Callaghan S, Anzanello F, Moyer TJ, Abraham W, Melo M, Silva M, Scaringi N, Rakasz EG, Sattentau Q, Irvine DJ, ... Burton DR, et al. Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization. Biorxiv : the Preprint Server For Biology. PMID 33619491 DOI: 10.1101/2021.02.16.431310 |
0.545 |
|
| 2021 |
Yuan M, Huang D, Lee CD, Wu NC, Jackson AM, Zhu X, Liu H, Peng L, van Gils MJ, Sanders RW, Burton DR, Reincke SM, Prüss H, Kreye J, Nemazee D, et al. Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Biorxiv : the Preprint Server For Biology. PMID 33619487 DOI: 10.1101/2021.02.16.430500 |
0.349 |
|
| 2021 |
Turman JM, Cheplowitz AM, Tiwari C, Thomas T, Joshi D, Bhat M, Wu Q, Pong E, Chu SY, Szymkowski DE, Sharma A, Seveau S, Robinson JM, Kwiek JJ, Burton D, et al. Accelerated Clearance and Degradation of Cell-Free HIV by Neutralizing Antibodies Occurs via FcγRIIb on Liver Sinusoidal Endothelial Cells by Endocytosis. Journal of Immunology (Baltimore, Md. : 1950). PMID 33568400 DOI: 10.4049/jimmunol.2000772 |
0.382 |
|
| 2021 |
Burton DR. A new lease on life for an HIV-neutralizing antibody class and vaccine target. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33504595 DOI: 10.1073/pnas.2026390118 |
0.469 |
|
| 2021 |
Rappazzo CG, Tse LV, Kaku CI, Wrapp D, Sakharkar M, Huang D, Deveau LM, Yockachonis TJ, Herbert AS, Battles MB, O'Brien CM, Brown ME, Geoghegan JC, Belk J, Peng L, ... ... Burton DR, et al. Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody. Science (New York, N.Y.). PMID 33495307 DOI: 10.1126/science.abf4830 |
0.311 |
|
| 2020 |
Huang D, Tran JT, Olson A, Vollbrecht T, Tenuta M, Guryleva MV, Fuller RP, Schiffner T, Abadejos JR, Couvrette L, Blane TR, Saye K, Li W, Landais E, Gonzalez-Martin A, ... ... Burton DR, et al. Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nature Communications. 11: 6360. PMID 33288767 DOI: 10.1038/s41467-020-20304-y |
0.442 |
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| 2020 |
Wu NC, Yuan M, Bangaru S, Huang D, Zhu X, Lee CD, Turner HL, Peng L, Yang L, Burton DR, Nemazee D, Ward AB, Wilson IA. A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody. Plos Pathogens. 16: e1009089. PMID 33275640 DOI: 10.1371/journal.ppat.1009089 |
0.313 |
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| 2020 |
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ. Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections. Viruses. 12. PMID 33255202 DOI: 10.3390/v12121346 |
0.34 |
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| 2020 |
Huang D, Tran JT, Olson A, Vollbrecht T, Tenuta M, Guryleva MV, Fuller RP, Schiffner T, Abadejos JR, Couvrette L, Blane TR, Saye K, Li W, Landais E, Gonzalez-Martin A, ... ... Burton DR, et al. Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells. Nature Communications. 11: 5850. PMID 33203876 DOI: 10.1038/s41467-020-19650-8 |
0.452 |
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| 2020 |
Martins MA, Gonzalez-Nieto L, Ricciardi MJ, Bailey VK, Dang CM, Bischof GF, Pedreño-Lopez N, Pauthner MG, Burton DR, Parks CL, Earl P, Moss B, Rakasz EG, Lifson JD, Desrosiers RC, et al. Rectal Acquisition of SIVmac239 Infection Despite Vaccine-Induced Immune Responses Against the Entire SIV Proteome. Journal of Virology. PMID 33028714 DOI: 10.1128/JVI.00979-20 |
0.444 |
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| 2020 |
Song G, He WT, Callaghan S, Anzanello F, Huang D, Ricketts J, Torres JL, Beutler N, Peng L, Vargas S, Cassell J, Parren M, Yang L, Ignacio C, Smith DM, ... ... Burton DR, et al. Cross-reactive serum and memory B cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection. Biorxiv : the Preprint Server For Biology. PMID 32995770 DOI: 10.1101/2020.09.22.308965 |
0.324 |
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| 2020 |
Zhao F, Joyce C, Burns A, Nogal B, Cottrell CA, Ramos A, Biddle T, Pauthner M, Nedellec R, Qureshi H, Mason R, Landais E, Briney B, Ward AB, Burton DR, et al. Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques. Cell Reports. 32: 108122. PMID 32905766 DOI: 10.1016/J.Celrep.2020.108122 |
0.526 |
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| 2020 |
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, ... ... Burton DR, et al. Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates. Plos Pathogens. 16: e1008753. PMID 32866207 DOI: 10.1371/Journal.Ppat.1008753 |
0.55 |
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| 2020 |
Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, et al. Structural basis of a shared antibody response to SARS-CoV-2. Science (New York, N.Y.). PMID 32661058 DOI: 10.1126/Science.Abd2321 |
0.431 |
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| 2020 |
Carnathan DG, Kaushik K, Ellebedy AH, Enemuo CA, Gebru EH, Dhadvai P, Rasheed MAU, Pauthner MG, Ozorowski G, Ahmed R, Burton DR, Ward AB, Silvestri G, Crotty S, Locci M. Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers. Frontiers in Immunology. 11: 1213. PMID 32612608 DOI: 10.3389/Fimmu.2020.01213 |
0.394 |
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| 2020 |
Yuan M, Liu H, Wu NC, Lee CD, Zhu X, Zhao F, Huang D, Yu W, Hua Y, Tien H, Rogers TF, Landais E, Sok D, Jardine JG, Burton DR, et al. Structural basis of a public antibody response to SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 32577642 DOI: 10.1101/2020.06.08.141267 |
0.425 |
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| 2020 |
Nogal B, McCoy LE, van Gils MJ, Cottrell CA, Voss JE, Andrabi R, Pauthner M, Liang CH, Messmer T, Nedellec R, Shin M, Turner HL, Ozorowski G, Sanders RW, Burton DR, et al. HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite. Science Advances. 6: eaba0512. PMID 32548265 DOI: 10.1126/Sciadv.Aba0512 |
0.476 |
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| 2020 |
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, ... ... Burton DR, et al. Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model. Science (New York, N.Y.). PMID 32540903 DOI: 10.1126/Science.Abc7520 |
0.415 |
|
| 2020 |
Wec AZ, Wrapp D, Herbert AS, Maurer DP, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... Burton DR, et al. Broad neutralization of SARS-related viruses by human monoclonal antibodies. Science (New York, N.Y.). PMID 32540900 DOI: 10.1126/Science.Abc7424 |
0.439 |
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| 2020 |
Stanfield RL, Berndsen ZT, Huang R, Sok D, Warner G, Torres JL, Burton DR, Ward AB, Wilson IA, Smider VV. Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Science Advances. 6: eaba0468. PMID 32518821 DOI: 10.1126/Sciadv.Aba0468 |
0.513 |
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| 2020 |
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, ... ... Burton DR, et al. Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model. Biorxiv : the Preprint Server For Biology. PMID 32511387 DOI: 10.1101/2020.05.11.088674 |
0.415 |
|
| 2020 |
Wec AZ, Wrapp D, Herbert AS, Maurer D, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, ... ... Burton DR, et al. Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein. Biorxiv : the Preprint Server For Biology. PMID 32511337 DOI: 10.1101/2020.05.15.096511 |
0.427 |
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| 2020 |
Burton DR, Walker LM. Rational Vaccine Design in the Time of COVID-19. Cell Host & Microbe. 27: 695-698. PMID 32407707 DOI: 10.1016/j.chom.2020.04.022 |
0.316 |
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| 2020 |
Nogal B, Bianchi M, Cottrell CA, Kirchdoerfer RN, Sewall LM, Turner HL, Zhao F, Sok D, Burton DR, Hangartner L, Ward AB. Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines. Cell Reports. 30: 3755-3765.e7. PMID 32187547 DOI: 10.1016/j.celrep.2020.02.061 |
0.506 |
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| 2020 |
Pedreño-Lopez N, Dang CM, Rosen BC, Ricciardi MJ, Bailey VK, Gutman MJ, Gonzalez-Nieto L, Pauthner MG, Le K, Song G, Andrabi R, Weisgrau KL, Pomplun N, Martinez-Navio JM, Fuchs SP, ... ... Burton DR, et al. Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies. Molecular Therapy. Methods & Clinical Development. 16: 225-237. PMID 32083148 DOI: 10.1016/J.Omtm.2020.01.010 |
0.416 |
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| 2020 |
Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, ... ... Burton DR, et al. Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nature Medicine. PMID 32066977 DOI: 10.1038/S41591-020-0753-3 |
0.392 |
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| 2020 |
Joyce C, Burton DR, Briney B. Comparisons of the antibody repertoires of a humanized rodent and humans by high throughput sequencing. Scientific Reports. 10: 1120. PMID 31980672 DOI: 10.1038/S41598-020-57764-7 |
0.334 |
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| 2020 |
Yang YR, McCoy LE, van Gils MJ, Andrabi R, Turner HL, Yuan M, Cottrell CA, Ozorowski G, Voss J, Pauthner M, Polveroni TM, Messmer T, Wilson IA, Sanders RW, Burton DR, et al. Autologous neutralizing antibody responses to an HIV envelope glycan hole are not easily broadened in rabbits. Journal of Virology. PMID 31941772 DOI: 10.1128/Jvi.01861-19 |
0.348 |
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| 2020 |
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, ... ... Burton DR, et al. Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance. Cell. 180: 206. PMID 31923396 DOI: 10.1016/j.cell.2019.12.027 |
0.419 |
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| 2019 |
Zhang L, Irimia A, He L, Landais E, Rantalainen K, Leaman DP, Vollbrecht T, Stano A, Sands DI, Kim AS, Poignard P, Burton DR, Murrell B, Ward AB, et al. An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nature Communications. 10: 5389. PMID 31772165 DOI: 10.1038/S41467-019-12973-1 |
0.483 |
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| 2019 |
Steichen JM, Lin YC, Havenar-Daughton C, Pecetta S, Ozorowski G, Willis JR, Toy L, Sok D, Liguori A, Kratochvil S, Torres JL, Kalyuzhniy O, Melzi E, Kulp DW, Raemisch S, ... ... Burton DR, et al. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science (New York, N.Y.). PMID 31672916 DOI: 10.1126/Science.Aax4380 |
0.547 |
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| 2019 |
Haynes BF, Burton DR, Mascola JR. Multiple roles for HIV broadly neutralizing antibodies. Science Translational Medicine. 11. PMID 31666399 DOI: 10.1126/scitranslmed.aaz2686 |
0.501 |
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| 2019 |
Pegu A, Borate B, Huang Y, Pauthner MG, Hessell AJ, Julg B, Doria-Rose NA, Schmidt SD, Carpp LN, Cully MD, Chen X, Shaw GM, Barouch DH, Haigwood NL, Corey L, ... Burton DR, et al. A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge. Cell Host & Microbe. 26: 336-346.e3. PMID 31513771 DOI: 10.1016/J.Chom.2019.08.014 |
0.378 |
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| 2019 |
Burton DR. Antibody barriers to going viral. The Journal of Experimental Medicine. PMID 31444247 DOI: 10.1084/jem.20191099 |
0.374 |
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| 2019 |
Umotoy J, Bagaya BS, Joyce C, Schiffner T, Menis S, Saye-Francisco KL, Biddle T, Mohan S, Vollbrecht T, Kalyuzhniy O, Madzorera S, Kitchin D, Lambson B, Nonyane M, Kilembe W, ... ... Burton DR, et al. Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan. Immunity. 51: 141-154.e6. PMID 31315032 DOI: 10.1016/J.Immuni.2019.06.004 |
0.529 |
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| 2019 |
von Bredow B, Andrabi R, Grunst M, Grandea AG, Le K, Song G, Berndsen ZT, Porter K, Pallesen J, Ward AB, Burton DR, Evans DT. Differences in the Binding Affinity of an HIV-1 V2 Apex-Specific Antibody for the SIV Envelope Glycoprotein Uncouple Antibody-Dependent Cellular Cytotoxicity from Neutralization. Mbio. 10. PMID 31266872 DOI: 10.1128/mBio.01255-19 |
0.533 |
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| 2019 |
Andrabi R, Pallesen J, Allen JD, Song G, Zhang J, de Val N, Gegg G, Porter K, Su CY, Pauthner M, Newman A, Bouton-Verville H, Garces F, Wilson IA, Crispin M, ... ... Burton DR, et al. The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template. Cell Reports. 27: 2426-2441.e6. PMID 31116986 DOI: 10.1016/J.Celrep.2019.04.082 |
0.471 |
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| 2019 |
Khan SN, Sok D, Tran K, Movsesyan A, Dubrovskaya V, Burton DR, Wyatt RT. Correction for Khan et al., "Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry". Journal of Virology. 93. PMID 31092683 DOI: 10.1128/JVI.00391-19 |
0.336 |
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| 2019 |
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, ... ... Burton DR, et al. Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance. Cell. PMID 31080066 DOI: 10.1016/J.Cell.2019.04.012 |
0.386 |
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| 2019 |
Seabright GE, Doores KJ, Burton DR, Crispin M. Protein and glycan mimicry in HIV vaccine design. Journal of Molecular Biology. PMID 31028779 DOI: 10.1016/j.jmb.2019.04.016 |
0.503 |
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| 2019 |
Sok D, Burton DR. Publisher Correction: Recent progress in broadly neutralizing antibodies to HIV. Nature Immunology. PMID 30705417 DOI: 10.1038/s41590-019-0329-x |
0.41 |
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| 2019 |
Briney B, Inderbitzin A, Joyce C, Burton DR. Commonality despite exceptional diversity in the baseline human antibody repertoire. Nature. PMID 30664748 DOI: 10.1038/S41586-019-0879-Y |
0.325 |
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| 2019 |
Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, ... ... Burton D, et al. Reprogramming the antigen specificity of B cells using genome-editing technologies. Elife. 8. PMID 30648968 DOI: 10.7554/Elife.42995 |
0.349 |
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| 2018 |
Allen ER, Krumm SA, Raghwani J, Halldorsson S, Elliott A, Graham VA, Koudriakova E, Harlos K, Wright D, Warimwe GM, Brennan B, Huiskonen JT, Dowall SD, Elliott RM, Pybus OG, ... Burton DR, et al. A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus. Cell Reports. 25: 3750-3758.e4. PMID 30590046 DOI: 10.1016/j.celrep.2018.12.001 |
0.409 |
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| 2018 |
Burton DR. Advancing an HIV vaccine; advancing vaccinology. Nature Reviews. Immunology. PMID 30560910 DOI: 10.1038/s41577-018-0103-6 |
0.385 |
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| 2018 |
Pauthner MG, Nkolola JP, Havenar-Daughton C, Murrell B, Reiss SM, Bastidas R, Prévost J, Nedellec R, von Bredow B, Abbink P, Cottrell CA, Kulp DW, Tokatlian T, Nogal B, Bianchi M, ... ... Burton DR, et al. Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers. Immunity. PMID 30552025 DOI: 10.1016/J.Immuni.2018.11.011 |
0.455 |
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| 2018 |
He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, ... Burton DR, et al. HIV-1 vaccine design through minimizing envelope metastability. Science Advances. 4: eaau6769. PMID 30474059 DOI: 10.1126/Sciadv.Aau6769 |
0.439 |
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| 2018 |
Sok D, Burton DR. Recent progress in broadly neutralizing antibodies to HIV. Nature Immunology. 19: 1179-1188. PMID 30333615 DOI: 10.1038/s41590-018-0235-7 |
0.525 |
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| 2018 |
Cao L, Pauthner M, Andrabi R, Rantalainen K, Berndsen Z, Diedrich JK, Menis S, Sok D, Bastidas R, Park SR, Delahunty CM, He L, Guenaga J, Wyatt RT, Schief WR, ... ... Burton DR, et al. Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer. Nature Communications. 9: 3693. PMID 30209313 DOI: 10.1038/s41467-018-06121-4 |
0.513 |
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| 2018 |
Bianchi M, Turner HL, Nogal B, Cottrell CA, Oyen D, Pauthner M, Bastidas R, Nedellec R, McCoy LE, Wilson IA, Burton DR, Ward AB, Hangartner L. Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization. Immunity. PMID 30097292 DOI: 10.1016/J.Immuni.2018.07.009 |
0.472 |
|
| 2018 |
Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, ... ... Burton DR, et al. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 174: 938-952.e13. PMID 30096313 DOI: 10.1016/J.Cell.2018.07.033 |
0.46 |
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| 2018 |
Khan SN, Sok D, Tran K, Movsesyan A, Dubrovskaya V, Burton D, Wyatt RT. Targeting the HIV-1 spike and co-receptor with bi- and trispecific antibodies for single-component broad inhibition of entry. Journal of Virology. PMID 29976677 DOI: 10.1128/JVI.00384-18 |
0.442 |
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| 2018 |
Ali A, Ng HL, Blankson JN, Burton DR, Buckheit RW, Moldt B, Fulcher JA, Ibarrondo FJ, Anton PA, Yang OO. Highly Attenuated Infection with a Vpr-Deleted Molecular Clone of HIV-1. The Journal of Infectious Diseases. PMID 29878133 DOI: 10.1093/Infdis/Jiy346 |
0.398 |
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| 2018 |
Martins MA, Tully DC, Pedreño-Lopez N, von Bredow B, Pauthner MG, Shin YC, Yuan M, Lima NS, Bean DJ, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Magnani DM, Ricciardi MJ, ... ... Burton DR, et al. + rhesus macaques vaccinated with , and manifest early control of SIVmac239 replication. Journal of Virology. PMID 29875239 DOI: 10.1128/Jvi.00690-18 |
0.4 |
|
| 2018 |
Andrabi R, Bhiman JN, Burton DR. Strategies for a multi-stage neutralizing antibody-based HIV vaccine. Current Opinion in Immunology. 53: 143-151. PMID 29775847 DOI: 10.1016/j.coi.2018.04.025 |
0.492 |
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| 2018 |
Shivatare VS, Shivatare SS, Lee CD, Liang CH, Liao KS, Cheng YY, Saidachary G, Wu CY, Lin NH, Kwong PD, Burton DR, Wu CY, Wong CH. Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies. Journal of the American Chemical Society. PMID 29578688 DOI: 10.1021/Jacs.8B00896 |
0.519 |
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| 2018 |
Zhou T, Zheng A, Baxa U, Chuang GY, Georgiev IS, Kong R, O'Dell S, Shahzad-Ul-Hussan S, Shen CH, Tsybovsky Y, Bailer RT, Gift SK, Louder MK, McKee K, Rawi R, ... ... Burton DR, et al. A Neutralizing Antibody Recognizing Primarily N-linked Glycan Targets the Silent Face of the HIV Envelope. Immunity. PMID 29548671 DOI: 10.1016/J.Immuni.2018.02.013 |
0.474 |
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| 2018 |
Cheng HD, Grimm SK, Gilman MS, Gwom LC, Sok D, Sundling C, Donofrio G, Hedestam GBK, Bonsignori M, Haynes BF, Lahey TP, Maro I, von Reyn CF, Gorny MK, Zolla-Pazner S, ... ... Burton DR, et al. Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site. Jci Insight. 3. PMID 29515029 DOI: 10.1172/Jci.Insight.97018 |
0.49 |
|
| 2018 |
Wagh K, Seaman MS, Zingg M, Fitzsimons T, Barouch DH, Burton DR, Connors M, Ho DD, Mascola JR, Nussenzweig MC, Ravetch J, Gautam R, Martin MA, Montefiori DC, Korber B. Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections. Plos Pathogens. 14: e1006860. PMID 29505593 DOI: 10.1371/Journal.Ppat.1006860 |
0.401 |
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| 2018 |
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, ... Burton DR, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 22: 1103. PMID 29386130 DOI: 10.1016/j.celrep.2017.10.089 |
0.414 |
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| 2018 |
Walker LM, Burton DR. Passive immunotherapy of viral infections: 'super-antibodies' enter the fray. Nature Reviews. Immunology. PMID 29379211 DOI: 10.1038/nri.2017.148 |
0.375 |
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| 2018 |
Teijaro JR, Burton DR. Taking down defenses to improve vaccines. Science (New York, N.Y.). 359: 277-278. PMID 29348225 DOI: 10.1126/Science.Aar5421 |
0.322 |
|
| 2017 |
Landais E, Murrell B, Briney B, Murrell S, Rantalainen K, Berndsen ZT, Ramos A, Wickramasinghe L, Smith ML, Eren K, de Val N, Wu M, Cappelletti A, Umotoy J, Lie Y, ... ... Burton DR, et al. HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity. 47: 990-1003.e9. PMID 29166592 DOI: 10.1016/J.Immuni.2017.11.002 |
0.469 |
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| 2017 |
Andrabi R, Su CY, Liang CH, Shivatare SS, Briney B, Voss JE, Nawazi SK, Wu CY, Wong CH, Burton DR. Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development. Immunity. 47: 1004. PMID 29166578 DOI: 10.1016/j.immuni.2017.10.012 |
0.484 |
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| 2017 |
Kulp DW, Steichen JM, Pauthner M, Hu X, Schiffner T, Liguori A, Cottrell CA, Havenar-Daughton C, Ozorowski G, Georgeson E, Kalyuzhniy O, Willis JR, Kubitz M, Adachi Y, Reiss SM, ... ... Burton DR, et al. Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding. Nature Communications. 8: 1655. PMID 29162799 DOI: 10.1038/S41467-017-01549-6 |
0.512 |
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| 2017 |
Magnani DM, Rogers TF, Beutler N, Ricciardi MJ, Bailey VK, Gonzalez-Nieto L, Briney B, Sok D, Le K, Strubel A, Gutman MJ, Pedreño-Lopez N, Grubaugh ND, Silveira CGT, Maxwell HS, ... ... Burton DR, et al. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Science Translational Medicine. 9. PMID 28978754 DOI: 10.1126/Scitranslmed.Aan8184 |
0.362 |
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| 2017 |
Voss JE, Andrabi R, McCoy LE, de Val N, Fuller RP, Messmer T, Su CY, Sok D, Khan SN, Garces F, Pritchard LK, Wyatt RT, Ward AB, Crispin M, Wilson IA, ... Burton DR, et al. Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model. Cell Reports. 21: 222-235. PMID 28978475 DOI: 10.1016/J.Celrep.2017.09.024 |
0.496 |
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| 2017 |
Julg B, Liu PT, Wagh K, Fischer WM, Abbink P, Mercado NB, Whitney JB, Nkolola JP, McMahan K, Tartaglia LJ, Borducchi EN, Khatiwada S, Kamath M, LeSuer JA, Seaman MS, ... ... Burton DR, et al. Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail. Science Translational Medicine. 9. PMID 28931655 DOI: 10.1126/Scitranslmed.Aao4235 |
0.467 |
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| 2017 |
Xu L, Pegu A, Rao E, Doria-Rose N, Beninga J, McKee K, Lord DM, Wei RR, Deng G, Louder M, Schmidt SD, Mankoff Z, Wu L, Asokan M, Beil C, ... ... Burton DR, et al. Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. Science (New York, N.Y.). PMID 28931639 DOI: 10.1126/Science.Aan8630 |
0.523 |
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| 2017 |
Andrabi R, Su CY, Liang CH, Shivatare SS, Briney B, Voss JE, Nawazi SK, Wu CY, Wong CH, Burton DR. Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development. Immunity. PMID 28916265 DOI: 10.1016/J.Immuni.2017.08.006 |
0.476 |
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| 2017 |
He L, Lin X, de Val N, Saye-Francisco KL, Mann CJ, Augst R, Morris CD, Azadnia P, Zhou B, Sok D, Ozorowski G, Ward AB, Burton DR, Zhu J. Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer. Frontiers in Immunology. 8: 1025. PMID 28883821 DOI: 10.3389/Fimmu.2017.01025 |
0.498 |
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| 2017 |
Magnani DM, Silveira CGT, Ricciardi MJ, Gonzalez-Nieto L, Pedreño-Lopez N, Bailey VK, Gutman MJ, Maxwell HS, Domingues A, Costa PR, Ferrari L, Goulart R, Martins MA, Martinez-Navio JM, Fuchs SP, ... ... Burton DR, et al. Potent Plasmablast-Derived Antibodies Elicited by the NIH Dengue Vaccine. Journal of Virology. PMID 28878078 DOI: 10.1128/Jvi.00867-17 |
0.383 |
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| 2017 |
Julg B, Tartaglia LJ, Keele BF, Wagh K, Pegu A, Sok D, Abbink P, Schmidt SD, Wang K, Chen X, Gordon Joyce M, Georgiev IS, Choe M, Kwong PD, Doria-Rose NA, ... ... Burton DR, et al. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Science Translational Medicine. 9. PMID 28878010 DOI: 10.1126/Scitranslmed.Aal1321 |
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| 2017 |
Nandin IS, Fong C, Deantonio C, Torreno-Pina JA, Pecetta S, Maldonado P, Gasparrini F, Ordovas-Montanes J, Kazer SW, Kjaer S, Borley DW, Nair U, Coleman JA, Lingwood D, Shalek AK, ... ... Burton DR, et al. Correction: Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. The Journal of Experimental Medicine. PMID 28827449 DOI: 10.1084/Jem.2017063307262017C |
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| 2017 |
Rogers TF, Goodwin EC, Briney B, Sok D, Beutler N, Strubel A, Nedellec R, Le K, Brown ME, Burton DR, Walker LM. Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors. Science Immunology. 2. PMID 28821561 DOI: 10.1126/Sciimmunol.Aan6809 |
0.33 |
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| 2017 |
Julg B, Sok D, Schmidt SD, Abbink P, Newman RM, Broge T, Linde C, Nkolola J, Le K, Su D, Torabi J, Pack M, Pegu A, Allen TM, Mascola JR, ... Burton DR, et al. Protective Efficacy of Broadly Neutralizing Antibodies with Incomplete Neutralization Activity Against SHIV in Rhesus Monkeys. Journal of Virology. PMID 28768869 DOI: 10.1128/Jvi.01187-17 |
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| 2017 |
Magnani DM, Ricciardi MJ, Bailey VK, Gutman MJ, Pedreño-Lopez N, Silveira CGT, Maxwell HS, Domingues A, Gonzalez-Nieto L, Su Q, Newman RM, Pack M, Martins MA, Martinez-Navio JM, Fuchs SP, ... ... Burton DR, et al. Dengue Virus Evades AAV-Mediated Neutralizing Antibody Prophylaxis in Rhesus Monkeys. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28750738 DOI: 10.1016/J.Ymthe.2017.06.020 |
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| 2017 |
Sanjuan Nandin I, Fong C, Deantonio C, Torreno-Pina JA, Pecetta S, Maldonado P, Gasparrini F, Ordovas-Montanes J, Kazer SW, Kjaer S, Borley DW, Nair U, Coleman JA, Lingwood D, Shalek AK, ... ... Burton DR, et al. Novel in vitro booster vaccination to rapidly generate antigen-specific human monoclonal antibodies. The Journal of Experimental Medicine. PMID 28739603 DOI: 10.1084/jem.20170633 |
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| 2017 |
Martins MA, Shin YC, Gonzalez-Nieto L, Domingues A, Gutman MJ, Maxwell HS, Castro I, Magnani DM, Ricciardi M, Pedreño-Lopez N, Bailey V, Betancourt D, Altman JD, Pauthner M, Burton DR, et al. Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques. Plos Pathogens. 13: e1006529. PMID 28732035 DOI: 10.1371/Journal.Ppat.1006529 |
0.342 |
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| 2017 |
Sok D, Le KM, Vadnais M, Saye-Francisco K, Jardine JG, Torres J, Berndsen ZT, Kong L, Stanfield R, Ruiz J, Ramos A, Liang CH, Chen PL, Criscitiello MF, Mwangi W, ... ... Burton DR, et al. Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows. Nature. PMID 28726771 DOI: 10.1038/Nature23301 |
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| 2017 |
Pauthner M, Havenar-Daughton C, Sok D, Nkolola JP, Bastidas R, Boopathy AV, Carnathan DG, Chandrashekar A, Cirelli KM, Cottrell CA, Eroshkin AM, Guenaga J, Kaushik K, Kulp DW, Liu J, ... ... Burton DR, et al. Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches. Immunity. 46: 1073-1088.e6. PMID 28636956 DOI: 10.1016/J.Immuni.2017.05.007 |
0.428 |
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| 2017 |
Magnani DM, Silveira CGT, Rosen BC, Ricciardi MJ, Pedreño-Lopez N, Gutman MJ, Bailey VK, Maxwell HS, Domingues A, Gonzalez-Nieto L, Avelino-Silva VI, Trindade M, Nogueira J, Oliveira CS, Maestri A, ... ... Burton DR, et al. A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus. Plos Neglected Tropical Diseases. 11: e0005655. PMID 28604797 DOI: 10.1371/Journal.Pntd.0005655 |
0.368 |
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| 2017 |
Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, ... ... Burton DR, et al. A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure. Immunity. 46: 690-702. PMID 28423342 DOI: 10.1016/J.Immuni.2017.03.017 |
0.503 |
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| 2017 |
Xie J, Sok D, Wu NC, Zheng T, Zhang W, Burton DR, Lerner RA. Immunochemical engineering of cell surfaces to generate virus resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396429 DOI: 10.1073/Pnas.1702764114 |
0.39 |
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| 2017 |
Cao L, Diedrich JK, Kulp DW, Pauthner M, He L, Park SR, Sok D, Su CY, Delahunty CM, Menis S, Andrabi R, Guenaga J, Georgeson E, Kubitz M, Adachi Y, ... Burton DR, et al. Global site-specific N-glycosylation analysis of HIV envelope glycoprotein. Nature Communications. 8: 14954. PMID 28348411 DOI: 10.1038/Ncomms14954 |
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| 2017 |
Haynes BF, Burton DR. Developing an HIV vaccine. Science (New York, N.Y.). 355: 1129-1130. PMID 28302812 DOI: 10.1126/science.aan0662 |
0.392 |
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| 2017 |
Morris CD, Azadnia P, de Val N, Vora N, Honda A, Giang E, Saye-Francisco K, Cheng Y, Lin X, Mann CJ, Tang J, Sok D, Burton DR, Law M, Ward AB, et al. Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers. Mbio. 8. PMID 28246356 DOI: 10.1128/mBio.00036-17 |
0.514 |
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| 2017 |
Irimia A, Serra AM, Sarkar A, Jacak R, Kalyuzhniy O, Sok D, Saye-Francisco KL, Schiffner T, Tingle R, Kubitz M, Adachi Y, Stanfield RL, Deller MC, Burton DR, Schief WR, et al. Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. Plos Pathogens. 13: e1006212. PMID 28225819 DOI: 10.1371/Journal.Ppat.1006212 |
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| 2017 |
Burton DR. What Are the Most Powerful Immunogen Design Vaccine Strategies? Reverse Vaccinology 2.0 Shows Great Promise. Cold Spring Harbor Perspectives in Biology. PMID 28159875 DOI: 10.1101/cshperspect.a030262 |
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| 2017 |
McCoy LE, Burton DR. Identification and specificity of broadly neutralizing antibodies against HIV. Immunological Reviews. 275: 11-20. PMID 28133814 DOI: 10.1111/imr.12484 |
0.509 |
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| 2017 |
Freund NT, Wang H, Scharf L, Nogueira L, Horwitz JA, Bar-On Y, Golijanin J, Sievers SA, Sok D, Cai H, Cesar Lorenzi JC, Halper-Stromberg A, Toth I, Piechocka-Trocha A, Gristick HB, ... ... Burton DR, et al. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Science Translational Medicine. 9. PMID 28100831 DOI: 10.1126/Scitranslmed.Aal2144 |
0.449 |
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| 2017 |
Wibmer CK, Gorman J, Ozorowski G, Bhiman JN, Sheward DJ, Elliott DH, Rouelle J, Smira A, Joyce MG, Ndabambi N, Druz A, Asokan M, Burton DR, Connors M, Abdool Karim SS, et al. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. Plos Pathogens. 13: e1006074. PMID 28076415 DOI: 10.1371/Journal.Ppat.1006074 |
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| 2016 |
Havenar-Daughton C, Carnathan DG, Torrents de la Peña A, Pauthner M, Briney B, Reiss SM, Wood JS, Kaushik K, van Gils MJ, Rosales SL, van der Woude P, Locci M, Le KM, de Taeye SW, Sok D, ... ... Burton DR, et al. Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer. Cell Reports. 17: 2195-2209. PMID 27880897 DOI: 10.1016/J.Celrep.2016.10.085 |
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| 2016 |
Sok D, Burton DR. HIV Broadly Neutralizing Antibodies: Taking Good Care Of The 98. Immunity. 45: 958-960. PMID 27851923 DOI: 10.1016/j.immuni.2016.10.033 |
0.464 |
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| 2016 |
van Gils MJ, van den Kerkhof TL, Ozorowski G, Cottrell CA, Sok D, Pauthner M, Pallesen J, de Val N, Yasmeen A, de Taeye SW, Schorcht A, Gumbs S, Johanna I, Saye-Francisco K, Liang CH, ... ... Burton DR, et al. An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability. Nature Microbiology. 2: 16199. PMID 27841852 DOI: 10.1038/Nmicrobiol.2016.199 |
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| 2016 |
Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EM, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, ... ... Burton DR, et al. Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathogens. 12: e1005905. PMID 27627763 DOI: 10.1371/Journal.Ppat.1005905 |
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| 2016 |
Steichen JM, Kulp DW, Tokatlian T, Escolano A, Dosenovic P, Stanfield RL, McCoy LE, Ozorowski G, Hu X, Kalyuzhniy O, Briney B, Schiffner T, Garces F, Freund NT, Gitlin AD, ... ... Burton DR, et al. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity. PMID 27617678 DOI: 10.1016/J.Immuni.2016.08.016 |
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| 2016 |
Briney B, Sok D, Jardine JG, Kulp DW, Skog P, Menis S, Jacak R, Kalyuzhniy O, de Val N, Sesterhenn F, Le KM, Ramos A, Jones M, Saye-Francisco KL, Blane TR, ... ... Burton DR, et al. Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies. Cell. 166: 1459-1470.e11. PMID 27610570 DOI: 10.1016/J.Cell.2016.08.005 |
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| 2016 |
Escolano A, Steichen JM, Dosenovic P, Kulp DW, Golijanin J, Sok D, Freund NT, Gitlin AD, Oliveira T, Araki T, Lowe S, Chen ST, Heinemann J, Yao KH, Georgeson E, ... ... Burton DR, et al. Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice. Cell. 166: 1445-1458.e12. PMID 27610569 DOI: 10.1016/J.Cell.2016.07.030 |
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| 2016 |
Sok D, Briney B, Jardine JG, Kulp DW, Menis S, Pauthner M, Wood A, Lee EC, Le KM, Jones M, Ramos A, Kalyuzhniy O, Adachi Y, Kubitz M, MacPherson S, ... ... Burton DR, et al. Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice. Science (New York, N.Y.). PMID 27608668 DOI: 10.1126/Science.Aah3945 |
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| 2016 |
Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, ... ... Burton DR, et al. Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design. Plos Pathogens. 12: e1005815. PMID 27560183 DOI: 10.1371/Journal.Ppat.1005815 |
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| 2016 |
Larrick JW, Alfenito MR, Scott JK, Parren PW, Burton DR, Bradbury AR, Lemere CA, Messer A, Huston JS, Carter PJ, Veldman T, Chester KA, Schurrman J, Adams GP, Reichert JM. Antibody Engineering & Therapeutics 2016: The Antibody Society's Annual Meeting December 11-15, 2016, San Diego, CA. Mabs. 0. PMID 27557809 DOI: 10.1080/19420862.2016.1227665 |
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| 2016 |
McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M, Menis S, Cottrell CA, Torres JL, Hsueh J, Schief WR, ... ... Burton DR, et al. Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies. Cell Reports. PMID 27545891 DOI: 10.1016/J.Celrep.2016.07.074 |
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| 2016 |
Liu J, Ghneim K, Sok D, Bosche WJ, Li Y, Chipriano E, Berkemeier B, Oswald K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Jimenez J, Mondesir J, ... ... Burton DR, et al. Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus. Science (New York, N.Y.). PMID 27540005 DOI: 10.1126/Science.Aag0491 |
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| 2016 |
Sok D, Pauthner M, Briney B, Lee JH, Saye-Francisco KL, Hsueh J, Ramos A, Le KM, Jones M, Jardine JG, Bastidas R, Sarkar A, Liang CH, Shivatare SS, Wu CY, ... ... Burton DR, et al. A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans. Immunity. 45: 31-45. PMID 27438765 DOI: 10.1016/J.Immuni.2016.06.026 |
0.457 |
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| 2016 |
Voss JE, Macauley MS, Rogers KA, Villinger F, Duan L, Shang L, Fink EA, Andrabi R, Colantonio AD, Robinson JE, Johnson RP, Burton DR, Haase AT. Reproducing SIVΔnef vaccine correlates of protection: trimeric gp41 antibody concentrated at mucosal front lines. Aids (London, England). PMID 27428745 DOI: 10.1097/Qad.0000000000001199 |
0.458 |
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| 2016 |
van den Kerkhof TL, de Taeye SW, Boeser-Nunnink BD, Burton DR, Kootstra NA, Schuitemaker H, Sanders RW, van Gils MJ. HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds. Retrovirology. 13: 48. PMID 27388013 DOI: 10.1186/s12977-016-0279-4 |
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| 2016 |
Deruaz M, Moldt B, Le KM, Power KA, Vrbanac VD, Tanno S, Ghebremichael MS, Allen TM, Tager AM, Burton DR, Luster AD. Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo. The Journal of Infectious Diseases. PMID 27357340 DOI: 10.1093/Infdis/Jiw203 |
0.416 |
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| 2016 |
He L, de Val N, Morris CD, Vora N, Thinnes TC, Kong L, Azadnia P, Sok D, Zhou B, Burton DR, Wilson IA, Nemazee D, Ward AB, Zhu J. Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles. Nature Communications. 7: 12041. PMID 27349934 DOI: 10.1038/Ncomms12041 |
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| 2016 |
Kong L, He L, de Val N, Vora N, Morris CD, Azadnia P, Sok D, Zhou B, Burton DR, Ward AB, Wilson IA, Zhu J. Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability. Nature Communications. 7: 12040. PMID 27349805 DOI: 10.1038/Ncomms12040 |
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| 2016 |
Moldt B, Le KM, Carnathan DG, Whitney JB, Schultz N, Lewis MG, Borducchi EN, Smith KM, Mackel JJ, Sweat SL, Hodges AP, Godzik A, Parren PW, Silvestri G, Barouch DH, ... Burton DR, et al. Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques. Aids (London, England). 30: 1543-1551. PMID 27243773 DOI: 10.1097/Qad.0000000000001102 |
0.456 |
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| 2016 |
MacLeod DT, Choi NM, Briney B, Garces F, Ver LS, Landais E, Murrell B, Wrin T, Kilembe W, Liang CH, Ramos A, Bian CB, Wickramasinghe L, Kong L, Eren K, ... ... Burton DR, et al. Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity. 44: 1215-1226. PMID 27192579 DOI: 10.1016/J.Immuni.2016.04.016 |
0.478 |
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| 2016 |
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, ... ... Burton DR, et al. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (New York, N.Y.). 352: 828-33. PMID 27174988 DOI: 10.1126/Science.Aae0474 |
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| 2016 |
Burton DR, Hangartner L. Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design. Annual Review of Immunology. 34: 635-59. PMID 27168247 DOI: 10.1146/annurev-immunol-041015-055515 |
0.55 |
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| 2016 |
von Bredow B, Arias JF, Heyer LN, Moldt B, Le K, Robinson JE, Zolla-Pazner S, Burton DR, Evans DT. Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-specific Monoclonal Antibodies. Journal of Virology. PMID 27122574 DOI: 10.1128/Jvi.00347-16 |
0.504 |
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| 2016 |
Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, ... ... Burton DR, et al. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. Cell. PMID 27114034 DOI: 10.1016/J.Cell.2016.04.010 |
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| 2016 |
Briney B, Le K, Zhu J, Burton DR. Clonify: unseeded antibody lineage assignment from next-generation sequencing data. Scientific Reports. 6: 23901. PMID 27102563 DOI: 10.1038/Srep23901 |
0.324 |
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| 2016 |
Wagh K, Bhattacharya T, Williamson C, Robles A, Bayne M, Garrity J, Rist M, Rademeyer C, Yoon H, Lapedes A, Gao H, Greene K, Louder MK, Kong R, Karim SA, ... Burton DR, et al. Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection. Plos Pathogens. 12: e1005520. PMID 27028935 DOI: 10.1371/Journal.Ppat.1005520 |
0.433 |
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| 2016 |
Jardine JG, Kulp DW, Havenar-Daughton C, Sarkar A, Briney B, Sok D, Sesterhenn F, Ereño-Orbea J, Kalyuzhniy O, Deresa I, Hu X, Spencer S, Jones M, Georgeson E, Adachi Y, ... ... Burton DR, et al. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science (New York, N.Y.). 351: 1458-63. PMID 27013733 DOI: 10.1126/Science.Aad9195 |
0.45 |
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| 2016 |
Moldt B, Le K, Carnathan DG, Whitney JB, Schultz N, Lewis MG, Borducchi E, Smith K, Mackel JJ, Sweat SL, Hodges AP, Godzik A, Parren PW, Silvestri G, Barouch DH, ... Burton DR, et al. Neutralizing antibody affords comparable protection against vaginal and rectal SHIV challenge in macaques. Aids (London, England). PMID 27003033 DOI: 10.1097/QAD.0000000000001102 |
0.45 |
|
| 2016 |
Shivatare SS, Chang SH, Tsai TI, Tseng SY, Shivatare VS, Lin YS, Cheng YY, Ren CT, Lee CC, Pawar S, Tsai CS, Shih HW, Zeng YF, Liang CH, Kwong PD, ... Burton DR, et al. Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies. Nature Chemistry. 8: 338-46. PMID 27001729 DOI: 10.1038/Nchem.2463 |
0.54 |
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| 2016 |
Behrens AJ, Vasiljevic S, Pritchard LK, Harvey DJ, Andev RS, Krumm SA, Struwe WB, Cupo A, Kumar A, Zitzmann N, Seabright GE, Kramer HB, Spencer DI, Royle L, Lee JH, ... ... Burton DR, et al. Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein. Cell Reports. PMID 26972002 DOI: 10.1016/J.Celrep.2016.02.058 |
0.424 |
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| 2016 |
Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, ... ... Burton DR, et al. Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak. Science (New York, N.Y.). PMID 26912366 DOI: 10.1126/Science.Aad5788 |
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| 2016 |
Krumm SA, Mohammed H, Le KM, Crispin M, Wrin T, Poignard P, Burton DR, Doores KJ. Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies. Retrovirology. 13: 8. PMID 26837192 DOI: 10.1186/s12977-016-0241-5 |
0.391 |
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| 2016 |
Jones TD, Carter PJ, Plückthun A, Vásquez M, Holgate RG, Hötzel I, Popplewell AG, Parren PW, Enzelberger M, Rademaker HJ, Clark MR, Lowe DC, Dahiyat BI, Smith V, Lambert JM, ... ... Burton DR, et al. The INNs and outs of antibody nonproprietary names. Mabs. 8: 1-9. PMID 26716992 DOI: 10.1080/19420862.2015.1114320 |
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| 2016 |
Krumm SA, Mohammed H, Le KM, Crispin M, Wrin T, Poignard P, Burton DR, Doores KJ. Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies Retrovirology. 13. DOI: 10.1186/s12977-016-0241-5 |
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| 2015 |
Garces F, Lee JH, de Val N, Torrents de la Pena A, Kong L, Puchades C, Hua Y, Stanfield RL, Burton DR, Moore JP, Sanders RW, Ward AB, Wilson IA. Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity. 43: 1053-63. PMID 26682982 DOI: 10.1016/J.Immuni.2015.11.007 |
0.5 |
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| 2015 |
Andrabi R, Voss JE, Liang CH, Briney B, McCoy LE, Wu CY, Wong CH, Poignard P, Burton DR. Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design. Immunity. 43: 959-973. PMID 26588781 DOI: 10.1016/J.Immuni.2015.10.014 |
0.477 |
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| 2015 |
Parren PW, Burton DR, Bradbury A, Huston JS, Carter PJ, Veldman T, Chester KA, Larrick JW, Alfenito MR, Scott JK, Weiner LM, Adams GP, Reichert JM. Antibody Engineering & Therapeutics 2015: The Antibody Society's annual meeting December 7-10, 2015, San Diego, CA. Mabs. 7: 981-8. PMID 26421752 DOI: 10.1080/19420862.2015.1089707 |
0.355 |
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| 2015 |
Lee JH, Leaman DP, Kim AS, Torrents de la Peña A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, et al. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nature Communications. 6: 8167. PMID 26404402 DOI: 10.1038/Ncomms9167 |
0.47 |
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| 2015 |
McCoy LE, Falkowska E, Doores KJ, Le K, Sok D, van Gils MJ, Euler Z, Burger JA, Seaman MS, Sanders RW, Schuitemaker H, Poignard P, Wrin T, Burton DR. Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies. Plos Pathogens. 11: e1005110. PMID 26267277 DOI: 10.1371/journal.ppat.1005110 |
0.483 |
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| 2015 |
Hu JK, Crampton JC, Cupo A, Ketas T, van Gils MJ, Sliepen K, de Taeye SW, Sok D, Ozorowski G, Deresa I, Stanfield R, Ward AB, Burton DR, Klasse PJ, Sanders RW, et al. Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity. Journal of Virology. PMID 26246566 DOI: 10.1128/Jvi.01653-15 |
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| 2015 |
Jardine JG, Ota T, Sok D, Pauthner M, Kulp DW, Kalyuzhniy O, Skog PD, Thinnes TC, Bhullar D, Briney B, Menis S, Jones M, Kubitz M, Spencer S, Adachi Y, ... Burton DR, et al. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen. Science (New York, N.Y.). PMID 26089355 DOI: 10.1126/Science.Aac5894 |
0.512 |
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| 2015 |
Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, ... ... Burton DR, et al. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science (New York, N.Y.). 349: aac4223. PMID 26089353 DOI: 10.1126/Science.Aac4223 |
0.524 |
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| 2015 |
Pritchard LK, Vasiljevic S, Ozorowski G, Seabright GE, Cupo A, Ringe R, Kim HJ, Sanders RW, Doores KJ, Burton DR, Wilson IA, Ward AB, Moore JP, Crispin M. Structural Constraints Determine the Glycosylation of HIV-1 Envelope Trimers. Cell Reports. 11: 1604-13. PMID 26051934 DOI: 10.1016/J.Celrep.2015.05.017 |
0.499 |
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| 2015 |
Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, ... ... Burton DR, et al. Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell. 161: 1280-92. PMID 26004070 DOI: 10.1016/J.Cell.2015.05.007 |
0.459 |
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| 2015 |
Burton DR, Mascola JR. Antibody responses to envelope glycoproteins in HIV-1 infection. Nature Immunology. 16: 571-6. PMID 25988889 DOI: 10.1038/ni.3158 |
0.516 |
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| 2015 |
Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, ... ... Burton DR, et al. Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. Mbio. 6. PMID 25900654 DOI: 10.1128/Mbio.00296-15 |
0.414 |
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| 2015 |
Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer. Plos Pathogens. 11: e1004767. PMID 25807248 DOI: 10.1371/Journal.Ppat.1004767 |
0.534 |
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| 2015 |
Gardner MR, Kattenhorn LM, Kondur HR, von Schaewen M, Dorfman T, Chiang JJ, Haworth KG, Decker JM, Alpert MD, Bailey CC, Neale ES, Fellinger CH, Joshi VR, Fuchs SP, Martinez-Navio JM, ... ... Burton DR, et al. AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges. Nature. 519: 87-91. PMID 25707797 DOI: 10.1038/Nature14264 |
0.474 |
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| 2015 |
Wang S, Mata-Fink J, Kriegsman B, Hanson M, Irvine DJ, Eisen HN, Burton DR, Wittrup KD, Kardar M, Chakraborty AK. Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies. Cell. 160: 785-97. PMID 25662010 DOI: 10.1016/J.Cell.2015.01.027 |
0.451 |
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| 2015 |
Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. Journal of Virology. 89: 3380-95. PMID 25589637 DOI: 10.1128/Jvi.03473-14 |
0.43 |
|
| 2015 |
Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, ... ... Burton DR, et al. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes. Virology. 475: 37-45. PMID 25462344 DOI: 10.1016/J.Virol.2014.10.032 |
0.397 |
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| 2015 |
Doores KJ, Kong L, Krumm SA, Le KM, Sok D, Laserson U, Garces F, Poignard P, Wilson IA, Burton DR. Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope. Journal of Virology. 89: 1105-18. PMID 25378488 DOI: 10.1128/Jvi.02905-14 |
0.495 |
|
| 2015 |
Schuster JE, Cox RG, Hastings AK, Boyd KL, Wadia J, Chen Z, Burton DR, Williamson RA, Williams JV. A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus. The Journal of Infectious Diseases. 211: 216-25. PMID 24864121 DOI: 10.1093/Infdis/Jiu307 |
0.347 |
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| 2015 |
Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, ... ... Burton DR, et al. Corrigendum to: Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes [Virology 475 (2015) 37-45] Virology. 478: 155-158. DOI: 10.1016/J.Virol.2015.01.023 |
0.3 |
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| 2014 |
Sok D, van Gils MJ, Pauthner M, Julien JP, Saye-Francisco KL, Hsueh J, Briney B, Lee JH, Le KM, Lee PS, Hua Y, Seaman MS, Moore JP, Ward AB, Wilson IA, ... ... Burton DR, et al. Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex. Proceedings of the National Academy of Sciences of the United States of America. 111: 17624-9. PMID 25422458 DOI: 10.1073/Pnas.1415789111 |
0.528 |
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| 2014 |
He L, Sok D, Azadnia P, Hsueh J, Landais E, Simek M, Koff WC, Poignard P, Burton DR, Zhu J. Toward a more accurate view of human B-cell repertoire by next-generation sequencing, unbiased repertoire capture and single-molecule barcoding. Scientific Reports. 4: 6778. PMID 25345460 DOI: 10.1038/srep06778 |
0.335 |
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| 2014 |
Munro JB, Gorman J, Ma X, Zhou Z, Arthos J, Burton DR, Koff WC, Courter JR, Smith AB, Kwong PD, Blanchard SC, Mothes W. Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions. Science (New York, N.Y.). 346: 759-63. PMID 25298114 DOI: 10.1126/Science.1254426 |
0.408 |
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| 2014 |
Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien JP, Hua Y, Cupo A, Moore JP, Paulson JC, Ward AB, Burton DR, Wilson IA. Structural evolution of glycan recognition by a family of potent HIV antibodies. Cell. 159: 69-79. PMID 25259921 DOI: 10.1016/J.Cell.2014.09.009 |
0.482 |
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| 2014 |
Hepler NL, Scheffler K, Weaver S, Murrell B, Richman DD, Burton DR, Poignard P, Smith DM, Kosakovsky Pond SL. IDEPI: rapid prediction of HIV-1 antibody epitopes and other phenotypic features from sequence data using a flexible machine learning platform. Plos Computational Biology. 10: e1003842. PMID 25254639 DOI: 10.1371/Journal.Pcbi.1003842 |
0.323 |
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| 2014 |
Del Prete GQ, Ailers B, Moldt B, Keele BF, Estes JD, Rodriguez A, Sampias M, Oswald K, Fast R, Trubey CM, Chertova E, Smedley J, LaBranche CC, Montefiori DC, Burton DR, et al. Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins. Cell Host & Microbe. 16: 412-8. PMID 25211081 DOI: 10.1016/J.Chom.2014.08.003 |
0.389 |
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| 2014 |
Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, Nason MC, Montefiori D, Moldt B, Poignard P, Diskin R, Bjorkman PJ, Eckhaus MA, Klein F, Mouquet H, ... ... Burton DR, et al. Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. The Journal of Experimental Medicine. 211: 2061-74. PMID 25155019 DOI: 10.1084/Jem.20132494 |
0.52 |
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| 2014 |
Li Q, Zeng M, Duan L, Voss JE, Smith AJ, Pambuccian S, Shang L, Wietgrefe S, Southern PJ, Reilly CS, Skinner PJ, Zupancic ML, Carlis JV, Piatak M, Waterman D, ... ... Burton DR, et al. Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry. Journal of Immunology (Baltimore, Md. : 1950). 193: 3113-25. PMID 25135832 DOI: 10.4049/Jimmunol.1400820 |
0.393 |
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| 2014 |
Zhou T, Zhu J, Yang Y, Gorman J, Ofek G, Srivatsan S, Druz A, Lees CR, Lu G, Soto C, Stuckey J, Burton DR, Koff WC, Connors M, Kwong PD, et al. Transplanting supersites of HIV-1 vulnerability. Plos One. 9: e99881. PMID 24992528 DOI: 10.1371/Journal.Pone.0099881 |
0.474 |
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| 2014 |
Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy. Journal of Virology. 88: 10177-88. PMID 24965454 DOI: 10.1128/Jvi.01229-14 |
0.421 |
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| 2014 |
Yasmeen A, Ringe R, Derking R, Cupo A, Julien JP, Burton DR, Ward AB, Wilson IA, Sanders RW, Moore JP, Klasse PJ. Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits. Retrovirology. 11: 41. PMID 24884783 DOI: 10.1186/1742-4690-11-41 |
0.509 |
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| 2014 |
Sok D, Doores KJ, Briney B, Le KM, Saye-Francisco KL, Ramos A, Kulp DW, Julien JP, Menis S, Wickramasinghe L, Seaman MS, Schief WR, Wilson IA, Poignard P, Burton DR. Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV. Science Translational Medicine. 6: 236ra63. PMID 24828077 DOI: 10.1126/Scitranslmed.3008104 |
0.375 |
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| 2014 |
Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Peña AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity. 40: 669-80. PMID 24768348 DOI: 10.1016/J.Immuni.2014.04.008 |
0.447 |
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| 2014 |
Falkowska E, Le KM, Ramos A, Doores KJ, Lee JH, Blattner C, Ramirez A, Derking R, van Gils MJ, Liang CH, Mcbride R, von Bredow B, Shivatare SS, Wu CY, Chan-Hui PY, ... ... Burton DR, et al. Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers. Immunity. 40: 657-68. PMID 24768347 DOI: 10.1016/J.Immuni.2014.04.009 |
0.564 |
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| 2014 |
Arias JF, Heyer LN, von Bredow B, Weisgrau KL, Moldt B, Burton DR, Rakasz EG, Evans DT. Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 111: 6425-30. PMID 24733916 DOI: 10.1073/pnas.1321507111 |
0.402 |
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| 2014 |
Diebolder CA, Beurskens FJ, de Jong RN, Koning RI, Strumane K, Lindorfer MA, Voorhorst M, Ugurlar D, Rosati S, Heck AJ, van de Winkel JG, Wilson IA, Koster AJ, Taylor RP, Saphire EO, ... Burton DR, et al. Complement is activated by IgG hexamers assembled at the cell surface. Science (New York, N.Y.). 343: 1260-3. PMID 24626930 DOI: 10.1126/Science.1248943 |
0.383 |
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| 2014 |
Asano S, Gavrilyuk J, Burton DR, Barbas CF. Preparation and activities of macromolecule conjugates of the CCR5 antagonist Maraviroc. Acs Medicinal Chemistry Letters. 5: 133-137. PMID 24563723 DOI: 10.1021/Ml400370W |
0.392 |
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| 2014 |
Trist HM, Tan PS, Wines BD, Ramsland PA, Orlowski E, Stubbs J, Gardiner EE, Pietersz GA, Kent SJ, Stratov I, Burton DR, Hogarth PM. Polymorphisms and interspecies differences of the activating and inhibitory FcγRII of Macaca nemestrina influence the binding of human IgG subclasses. Journal of Immunology (Baltimore, Md. : 1950). 192: 792-803. PMID 24342805 DOI: 10.4049/Jimmunol.1301554 |
0.399 |
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| 2014 |
Ruwona TB, Mcbride R, Chappel R, Head SR, Ordoukhanian P, Burton DR, Law M. Optimization of peptide arrays for studying antibodies to hepatitis C virus continuous epitopes. Journal of Immunological Methods. 402: 35-42. PMID 24269751 DOI: 10.1016/j.jim.2013.11.005 |
0.311 |
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| 2014 |
Eroshkin AM, LeBlanc A, Weekes D, Post K, Li Z, Rajput A, Butera ST, Burton DR, Godzik A. bNAber: database of broadly neutralizing HIV antibodies. Nucleic Acids Research. 42: D1133-9. PMID 24214957 DOI: 10.1093/Nar/Gkt1083 |
0.422 |
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| 2014 |
Moldt B, Saye-Francisco K, Schultz N, Burton DR, Hessell AJ. Simplifying the synthesis of SIgA: combination of dIgA and rhSC using affinity chromatography. Methods (San Diego, Calif.). 65: 127-32. PMID 23811333 DOI: 10.1016/j.ymeth.2013.06.022 |
0.335 |
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| 2013 |
Ferguson AL, Falkowska E, Walker LM, Seaman MS, Burton DR, Chakraborty AK. Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data. Plos One. 8: e80562. PMID 24312481 DOI: 10.1371/Journal.Pone.0080562 |
0.509 |
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| 2013 |
McMichael A, Picker LJ, Moore JP, Burton DR. Another HIV vaccine failure: where to next? Nature Medicine. 19: 1576-7. PMID 24309655 DOI: 10.1038/nm.3413 |
0.367 |
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| 2013 |
Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, ... Burton DR, et al. The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells. Plos Pathogens. 9: e1003776. PMID 24278022 DOI: 10.1371/Journal.Ppat.1003776 |
0.443 |
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| 2013 |
Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, ... ... Burton DR, et al. The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies. Plos Pathogens. 9: e1003754. PMID 24278016 DOI: 10.1371/Journal.Ppat.1003754 |
0.536 |
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| 2013 |
Sok D, Moldt B, Burton DR. SnapShot: broadly neutralizing antibodies. Cell. 155: 728-728.e1. PMID 24243025 DOI: 10.1016/j.cell.2013.10.009 |
0.381 |
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| 2013 |
Lyumkis D, Julien JP, de Val N, Cupo A, Potter CS, Klasse PJ, Burton DR, Sanders RW, Moore JP, Carragher B, Wilson IA, Ward AB. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 342: 1484-90. PMID 24179160 DOI: 10.1126/Science.1245627 |
0.421 |
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| 2013 |
Julien JP, Cupo A, Sok D, Stanfield RL, Lyumkis D, Deller MC, Klasse PJ, Burton DR, Sanders RW, Moore JP, Ward AB, Wilson IA. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science (New York, N.Y.). 342: 1477-83. PMID 24179159 DOI: 10.1126/Science.1245625 |
0.396 |
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| 2013 |
Barouch DH, Whitney JB, Moldt B, Klein F, Oliveira TY, Liu J, Stephenson KE, Chang HW, Shekhar K, Gupta S, Nkolola JP, Seaman MS, Smith KM, Borducchi EN, Cabral C, ... ... Burton DR, et al. Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature. 503: 224-8. PMID 24172905 DOI: 10.1038/Nature12744 |
0.484 |
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| 2013 |
Doyle-Cooper C, Hudson KE, Cooper AB, Ota T, Skog P, Dawson PE, Zwick MB, Schief WR, Burton DR, Nemazee D. Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10. Journal of Immunology (Baltimore, Md. : 1950). 191: 3186-91. PMID 23940276 DOI: 10.4049/Jimmunol.1301285 |
0.368 |
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| 2013 |
Ota T, Doyle-Cooper C, Cooper AB, Doores KJ, Aoki-Ota M, Le K, Schief WR, Wyatt RT, Burton DR, Nemazee D. B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates. Journal of Immunology (Baltimore, Md. : 1950). 191: 3179-85. PMID 23940273 DOI: 10.4049/Jimmunol.1301283 |
0.403 |
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| 2013 |
Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, ... ... Burton DR, et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity. 39: 245-58. PMID 23911655 DOI: 10.1016/J.Immuni.2013.04.012 |
0.468 |
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| 2013 |
Jaworski JP, Kobie J, Brower Z, Malherbe DC, Landucci G, Sutton WF, Guo B, Reed JS, Leon EJ, Engelmann F, Zheng B, Legasse A, Park B, Dickerson M, Lewis AD, ... ... Burton DR, et al. Neutralizing polyclonal IgG present during acute infection prevents rapid disease onset in simian-human immunodeficiency virus SHIVSF162P3-infected infant rhesus macaques. Journal of Virology. 87: 10447-59. PMID 23885083 DOI: 10.1128/Jvi.00049-13 |
0.332 |
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| 2013 |
Amin MN, McLellan JS, Huang W, Orwenyo J, Burton DR, Koff WC, Kwong PD, Wang LX. Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies. Nature Chemical Biology. 9: 521-6. PMID 23831758 DOI: 10.1038/Nchembio.1288 |
0.546 |
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| 2013 |
Ahmed R, Burton DR. Viral vaccines: past successes and future challenges. Current Opinion in Virology. 3: 307-8. PMID 23809262 DOI: 10.1016/J.Coviro.2013.06.007 |
0.365 |
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| 2013 |
Sato S, Inokuma T, Otsubo N, Burton DR, Barbas CF. Chemically Programmed Antibodies AS HIV-1 Attachment Inhibitors. Acs Medicinal Chemistry Letters. 4: 460-465. PMID 23750312 DOI: 10.1021/Ml400097Z |
0.472 |
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| 2013 |
Pancera M, Shahzad-Ul-Hussan S, Doria-Rose NA, McLellan JS, Bailer RT, Dai K, Loesgen S, Louder MK, Staupe RP, Yang Y, Zhang B, Parks R, Eudailey J, Lloyd KE, Blinn J, ... ... Burton DR, et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nature Structural & Molecular Biology. 20: 804-13. PMID 23708607 DOI: 10.1038/Nsmb.2600 |
0.478 |
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| 2013 |
Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, ... ... Burton DR, et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nature Structural & Molecular Biology. 20: 796-803. PMID 23708606 DOI: 10.1038/Nsmb.2594 |
0.497 |
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| 2013 |
Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, ... ... Burton DR, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathogens. 9: e1003342. PMID 23658524 DOI: 10.1371/Journal.Ppat.1003342 |
0.443 |
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| 2013 |
Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, et al. Rational HIV immunogen design to target specific germline B cell receptors. Science (New York, N.Y.). 340: 711-6. PMID 23539181 DOI: 10.1126/Science.1234150 |
0.47 |
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| 2013 |
Zhu J, Ofek G, Yang Y, Zhang B, Louder MK, Lu G, McKee K, Pancera M, Skinner J, Zhang Z, Parks R, Eudailey J, Lloyd KE, Blinn J, Alam SM, ... ... Burton DR, et al. Mining the antibodyome for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains. Proceedings of the National Academy of Sciences of the United States of America. 110: 6470-5. PMID 23536288 DOI: 10.1073/Pnas.1219320110 |
0.35 |
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| 2013 |
Hoffenberg S, Powell R, Carpov A, Wagner D, Wilson A, Kosakovsky Pond S, Lindsay R, Arendt H, Destefano J, Phogat S, Poignard P, Fling SP, Simek M, Labranche C, Montefiori D, ... ... Burton D, et al. Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes. Journal of Virology. 87: 5372-83. PMID 23468492 DOI: 10.1128/Jvi.02827-12 |
0.61 |
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| 2013 |
Pancera M, Yang Y, Louder MK, Gorman J, Lu G, McLellan JS, Stuckey J, Zhu J, Burton DR, Koff WC, Mascola JR, Kwong PD. N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function. Plos One. 8: e55701. PMID 23431362 DOI: 10.1371/journal.pone.0055701 |
0.452 |
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| 2013 |
Gavrilyuk J, Ban H, Uehara H, Sirk SJ, Saye-Francisco K, Cuevas A, Zablowsky E, Oza A, Seaman MS, Burton DR, Barbas CF. Antibody conjugation approach enhances breadth and potency of neutralization of anti-HIV-1 antibodies and CD4-IgG. Journal of Virology. 87: 4985-93. PMID 23427154 DOI: 10.1128/Jvi.03146-12 |
0.513 |
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| 2013 |
Hoot S, McGuire AT, Cohen KW, Strong RK, Hangartner L, Klein F, Diskin R, Scheid JF, Sather DN, Burton DR, Stamatatos L. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs. Plos Pathogens. 9: e1003106. PMID 23300456 DOI: 10.1371/Journal.Ppat.1003106 |
0.496 |
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| 2013 |
Doores KJ, Huber M, Le KM, Wang SK, Doyle-Cooper C, Cooper A, Pantophlet R, Wong CH, Nemazee D, Burton DR. 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies. Journal of Virology. 87: 2234-41. PMID 23221565 DOI: 10.1128/Jvi.02820-12 |
0.451 |
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| 2013 |
Benhnia MR, Maybeno M, Blum D, Aguilar-Sino R, Matho M, Meng X, Head S, Felgner PL, Zajonc DM, Koriazova L, Kato S, Burton DR, Xiang Y, Crowe JE, Peters B, et al. Unusual features of vaccinia virus extracellular virion form neutralization resistance revealed in human antibody responses to the smallpox vaccine. Journal of Virology. 87: 1569-85. PMID 23152530 DOI: 10.1128/Jvi.02152-12 |
0.37 |
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| 2013 |
Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien J, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, ... ... Burton DR, et al. Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies Plos Pathogens. 9. DOI: 10.1371/annotation/f1f8c791-61e9-45c6-a455-92c6dadf9f06 |
0.457 |
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| 2013 |
Hoot S, McGuire AT, Cohen KW, Strong RK, Hangartner L, Klein F, Diskin R, Scheid JF, Sather DN, Burton DR, Stamatatos L. Correction: Recombinant HIV Envelope Proteins Fail to Engage Germline Versions of Anti-CD4bs bNAbs Plos Pathogens. 9. DOI: 10.1371/Annotation/Ed7C0148-97Eb-4416-824D-6E6D1Aaeceef |
0.319 |
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| 2013 |
Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping L, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, ... Burton DR, et al. Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells Plos Pathogens. 9. DOI: 10.1371/annotation/31430955-703b-484a-96eb-e180f917d683 |
0.322 |
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| 2013 |
Beurskens FJ, de Jong RN, Verploegen S, Voorhorst M, Strumane K, Lindorfer MA, Taylor RP, Saphire EO, Burton D, Schuurman J, Parren PW. Enhanced IgG Hexamerization Mediates Efficient C1q Docking and Complement-Dependent Cytotoxicity; Preclinical Proof Of Concept On Primary CLL and Burkitt Lymphoma Blood. 122: 375-375. DOI: 10.1182/Blood.V122.21.375.375 |
0.443 |
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| 2013 |
Beurskens F, de Jong R, Voorhorst M, Strumane K, Lindorfer M, Taylor R, Ollmann-Saphire E, Burton D, Schuurman J, Parren P. IgG hexamerization mediates efficient C1q docking and complement-dependent cytotoxicity (CDC) Molecular Immunology. 56: 240-241. DOI: 10.1016/J.Molimm.2013.05.012 |
0.337 |
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| 2012 |
Moldt B, Rakasz EG, Schultz N, Chan-Hui PY, Swiderek K, Weisgrau KL, Piaskowski SM, Bergman Z, Watkins DI, Poignard P, Burton DR. Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 18921-5. PMID 23100539 DOI: 10.1073/Pnas.1214785109 |
0.406 |
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| 2012 |
Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, et al. A Blueprint for HIV Vaccine Discovery. Cell Host & Microbe. 12: 396-407. PMID 23084910 DOI: 10.1016/J.Chom.2012.09.008 |
0.477 |
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| 2012 |
Ota T, Doyle-Cooper C, Cooper AB, Huber M, Falkowska E, Doores KJ, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola JR, Poignard P, Binley JM, ... ... Burton DR, et al. Anti-HIV B Cell lines as candidate vaccine biosensors. Journal of Immunology (Baltimore, Md. : 1950). 189: 4816-24. PMID 23066156 DOI: 10.4049/Jimmunol.1202165 |
0.417 |
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| 2012 |
Zhu J, O'Dell S, Ofek G, Pancera M, Wu X, Zhang B, Zhang Z, Mullikin JC, Simek M, Burton DR, Koff WC, Shapiro L, Mascola JR, Kwong PD. Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics. Frontiers in Microbiology. 3: 315. PMID 23024643 DOI: 10.3389/Fmicb.2012.00315 |
0.356 |
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| 2012 |
Poignard P, Moldt B, Maloveste K, Campos N, Olson WC, Rakasz E, Watkins DI, Burton DR. Protection against high-dose highly pathogenic mucosal SIV challenge at very low serum neutralizing titers of the antibody-like molecule CD4-igG2 Plos One. 7. PMID 22848744 DOI: 10.1371/Journal.Pone.0042209 |
0.371 |
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| 2012 |
Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science (New York, N.Y.). 337: 183-6. PMID 22798606 DOI: 10.1126/Science.1225416 |
0.489 |
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| 2012 |
Doria-Rose NA, Georgiev I, O'Dell S, Chuang GY, Staupe RP, McLellan JS, Gorman J, Pancera M, Bonsignori M, Haynes BF, Burton DR, Koff WC, Kwong PD, Mascola JR. A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies. Journal of Virology. 86: 8319-23. PMID 22623764 DOI: 10.1128/Jvi.00696-12 |
0.34 |
|
| 2012 |
Giang E, Dorner M, Prentoe JC, Dreux M, Evans MJ, Bukh J, Rice CM, Ploss A, Burton DR, Law M. Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 109: 6205-10. PMID 22492964 DOI: 10.1073/Pnas.1114927109 |
0.308 |
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| 2012 |
Moldt B, Shibata-Koyama M, Rakasz EG, Schultz N, Kanda Y, Dunlop DC, Finstad SL, Jin C, Landucci G, Alpert MD, Dugast AS, Parren PW, Nimmerjahn F, Evans DT, Alter G, ... ... Burton DR, et al. A nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcγRIIIa-mediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques. Journal of Virology. 86: 6189-96. PMID 22457527 DOI: 10.1128/Jvi.00491-12 |
0.488 |
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| 2012 |
Falkowska E, Ramos A, Feng Y, Zhou T, Moquin S, Walker LM, Wu X, Seaman MS, Wrin T, Kwong PD, Wyatt RT, Mascola JR, Poignard P, Burton DR. PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4. Journal of Virology. 86: 4394-403. PMID 22345481 DOI: 10.1128/JVI.06973-11 |
0.355 |
|
| 2012 |
Montero M, Gulzar N, Klaric KA, Donald JE, Lepik C, Wu S, Tsai S, Julien JP, Hessell AJ, Wang S, Lu S, Burton DR, Pai EF, Degrado WF, Scott JK. Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane. Journal of Virology. 86: 2930-41. PMID 22238313 DOI: 10.1128/Jvi.06349-11 |
0.362 |
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| 2012 |
Ahmed FK, Clark BE, Burton DR, Pantophlet R. An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site. Vaccine. 30: 922-30. PMID 22142583 DOI: 10.1016/j.vaccine.2011.11.089 |
0.529 |
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| 2012 |
Sharma S, Pokorski J, Finn M, Jacqueline J, Rakasz E, Burton D, Wyatt R. Assessing the protective efficacy of antibodies to the HIV gp41 region by active vaccination Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P37 |
0.608 |
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| 2012 |
Hoffenberg S, Pond SK, Carpov A, Wagner D, Wilson A, Powell R, Lindsay R, Arendt H, DeStefano J, Poignard P, Simek M, Fling S, Phogat S, Labranche C, Montefiori D, ... Burton D, et al. Identification of a clade A HIV envelope immunogen from Protocol G that elicits neutralizing antibodies to tier 2 viruses Retrovirology. 9: 1-1. DOI: 10.1186/1742-4690-9-S2-O7 |
0.556 |
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| 2012 |
Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses Science. 337: 183-186. DOI: 10.1126/science.1225416 |
0.383 |
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| 2012 |
Kong L, Julien JP, Calarese D, Scanlan C, Lee HK, Rudd P, Wong CH, Dwek RA, Burton DR, Wilson IA. Toward a carbohydrate-based HIV-1 vaccine Acs Symposium Series. 1102: 187-215. DOI: 10.1021/bk-2012-1102.ch007 |
0.398 |
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| 2011 |
Walker LM, Sok D, Nishimura Y, Donau O, Sadjadpour R, Gautam R, Shingai M, Pejchal R, Ramos A, Simek MD, Geng Y, Wilson IA, Poignard P, Martin MA, Burton DR. Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque. Proceedings of the National Academy of Sciences of the United States of America. 108: 20125-9. PMID 22123961 DOI: 10.1073/Pnas.1117531108 |
0.461 |
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| 2011 |
McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, ... ... Burton DR, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/Nature10696 |
0.369 |
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| 2011 |
Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, ... ... Burton DR, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (New York, N.Y.). 334: 1097-103. PMID 21998254 DOI: 10.1126/Science.1213256 |
0.52 |
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| 2011 |
Bonomelli C, Doores KJ, Dunlop DC, Thaney V, Dwek RA, Burton DR, Crispin M, Scanlan CN. The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade. Plos One. 6: e23521. PMID 21858152 DOI: 10.1371/Journal.Pone.0023521 |
0.414 |
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| 2011 |
Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, ... ... Burton DR, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature. 477: 466-70. PMID 21849977 DOI: 10.1038/Nature10373 |
0.556 |
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| 2011 |
Moldt B, Schultz N, Dunlop DC, Alpert MD, Harvey JD, Evans DT, Poignard P, Hessell AJ, Burton DR. A panel of IgG1 b12 variants with selectively diminished or enhanced affinity for Fcγ receptors to define the role of effector functions in protection against HIV. Journal of Virology. 85: 10572-81. PMID 21849450 DOI: 10.1128/Jvi.05541-11 |
0.461 |
|
| 2011 |
Nicolaou KC, Ellery SP, Rivas F, Saye K, Rogers E, Workinger TJ, Schallenberger M, Tawatao R, Montero A, Hessell A, Romesberg F, Carson D, Burton D. Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues. Bioorganic & Medicinal Chemistry. 19: 5648-69. PMID 21840722 DOI: 10.1016/J.Bmc.2011.07.022 |
0.308 |
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| 2011 |
Wu X, Zhou T, Zhu J, Zhang B, Georgiev I, Wang C, Chen X, Longo NS, Louder M, McKee K, O'Dell S, Perfetto S, Schmidt SD, Shi W, Wu L, ... ... Burton DR, et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science (New York, N.Y.). 333: 1593-602. PMID 21835983 DOI: 10.1126/science.1207532 |
0.482 |
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| 2011 |
Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, Pietzsch J, Fenyo D, Abadir A, Velinzon K, Hurley A, Myung S, Boulad F, Poignard P, Burton DR, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (New York, N.Y.). 333: 1633-7. PMID 21764753 DOI: 10.1126/Science.1207227 |
0.517 |
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| 2011 |
Agrawal N, Leaman DP, Rowcliffe E, Kinkead H, Nohria R, Akagi J, Bauer K, Du SX, Whalen RG, Burton DR, Zwick MB. Functional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1). Plos One. 6: e21339. PMID 21738637 DOI: 10.1371/Journal.Pone.0021339 |
0.353 |
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| 2011 |
Du SX, Xu L, Zhang W, Tang S, Boenig RI, Chen H, Mariano EB, Zwick MB, Parren PW, Burton DR, Wrin T, Petropoulos CJ, Ballantyne JA, Chambers M, Whalen RG. A directed molecular evolution approach to improved immunogenicity of the HIV-1 envelope glycoprotein. Plos One. 6: e20927. PMID 21738594 DOI: 10.1371/journal.pone.0020927 |
0.525 |
|
| 2011 |
Li Y, O'Dell S, Walker LM, Wu X, Guenaga J, Feng Y, Schmidt SD, McKee K, Louder MK, Ledgerwood JE, Graham BS, Haynes BF, Burton DR, Wyatt RT, Mascola JR. Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01. Journal of Virology. 85: 8954-67. PMID 21715490 DOI: 10.1128/Jvi.00754-11 |
0.412 |
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| 2011 |
Burton DR, Hessell AJ, Keele BF, Klasse PJ, Ketas TA, Moldt B, Dunlop DC, Poignard P, Doyle LA, Cavacini L, Veazey RS, Moore JP. Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America. 108: 11181-6. PMID 21690411 DOI: 10.1073/pnas.1103012108 |
0.469 |
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| 2011 |
Chakrabarti BK, Walker LM, Guenaga JF, Ghobbeh A, Poignard P, Burton DR, Wyatt RT. Direct antibody access to the HIV-1 membrane-proximal external region positively correlates with neutralization sensitivity. Journal of Virology. 85: 8217-26. PMID 21653673 DOI: 10.1128/JVI.00756-11 |
0.441 |
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| 2011 |
Burton D, Mascola J, Michael N, Overbaugh J. As antibody findings mount, what comes next? Interview by Kristen Jill Kresge and Regina McEnery. Iavi Report : Newsletter On International Aids Vaccine Research. 15: 4-7. PMID 21449503 |
0.355 |
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| 2011 |
Ackerman ME, Moldt B, Wyatt RT, Dugast AS, McAndrew E, Tsoukas S, Jost S, Berger CT, Sciaranghella G, Liu Q, Irvine DJ, Burton DR, Alter G. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. Journal of Immunological Methods. 366: 8-19. PMID 21192942 DOI: 10.1016/J.Jim.2010.12.016 |
0.401 |
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| 2011 |
Weinfurter JT, May GE, Soma T, Hessell AJ, León EJ, Macnair CE, Piaskowski SM, Weisgrau K, Furlott J, Maness NJ, Reed J, Wilson NA, Rakasz EG, Burton DR, Friedrich TC. Macaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus. Journal of Virology. 85: 530-41. PMID 20962091 DOI: 10.1128/JVI.01025-10 |
0.305 |
|
| 2010 |
Ng CT, Jaworski JP, Jayaraman P, Sutton WF, Delio P, Kuller L, Anderson D, Landucci G, Richardson BA, Burton DR, Forthal DN, Haigwood NL. Passive neutralizing antibody controls SHIV viremia and enhances B cell responses in infant macaques. Nature Medicine. 16: 1117-9. PMID 20890292 DOI: 10.1038/Nm.2233 |
0.395 |
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| 2010 |
Doores KJ, Fulton Z, Hong V, Patel MK, Scanlan CN, Wormald MR, Finn MG, Burton DR, Wilson IA, Davis BG. A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proceedings of the National Academy of Sciences of the United States of America. 107: 17107-12. PMID 20852065 DOI: 10.1073/Pnas.1002717107 |
0.565 |
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| 2010 |
Gavrilyuk J, Uehara H, Otsubo N, Hessell A, Burton DR, Barbas CF. Potent inhibition of HIV-1 entry with a chemically programmed antibody aided by an efficient organocatalytic synthesis. Chembiochem : a European Journal of Chemical Biology. 11: 2113-8. PMID 20845359 DOI: 10.1002/Cbic.201000432 |
0.39 |
|
| 2010 |
Burton DR, Weiss RA. AIDS/HIV. A boost for HIV vaccine design. Science (New York, N.Y.). 329: 770-3. PMID 20705840 DOI: 10.1126/Science.1194693 |
0.554 |
|
| 2010 |
Doores KJ, Fulton Z, Huber M, Wilson IA, Burton DR. Antibody 2G12 recognizes di-mannose equivalently in domain- and nondomain-exchanged forms but only binds the HIV-1 glycan shield if domain exchanged. Journal of Virology. 84: 10690-9. PMID 20702629 DOI: 10.1128/Jvi.01110-10 |
0.49 |
|
| 2010 |
Walker LM, Simek MD, Priddy F, Gach JS, Wagner D, Zwick MB, Phogat SK, Poignard P, Burton DR. A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals Plos Pathogens. 6: 11-12. PMID 20700449 DOI: 10.1371/journal.ppat.1001028 |
0.534 |
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| 2010 |
Doores KJ, Burton DR. Variable loop glycan dependency of the broad and potent HIV-1-neutralizing antibodies PG9 and PG16. Journal of Virology. 84: 10510-21. PMID 20686044 DOI: 10.1128/JVI.00552-10 |
0.503 |
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| 2010 |
Doores KJ, Bonomelli C, Harvey DJ, Vasiljevic S, Dwek RA, Burton DR, Crispin M, Scanlan CN. Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens. Proceedings of the National Academy of Sciences of the United States of America. 107: 13800-5. PMID 20643940 DOI: 10.1073/Pnas.1006498107 |
0.533 |
|
| 2010 |
Reynolds MR, Weiler AM, Piaskowski SM, Kolar HL, Hessell AJ, Weiker M, Weisgrau KL, León EJ, Rogers WE, Makowsky R, McDermott AB, Boyle R, Wilson NA, Allison DB, Burton DR, et al. Macaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge. Journal of Virology. 84: 9190-9. PMID 20592091 DOI: 10.1128/Jvi.00041-10 |
0.323 |
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| 2010 |
Pejchal R, Walker LM, Stanfield RL, Phogat SK, Koff WC, Poignard P, Burton DR, Wilson IA. Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1. Proceedings of the National Academy of Sciences of the United States of America. 107: 11483-8. PMID 20534513 DOI: 10.1073/Pnas.1004600107 |
0.53 |
|
| 2010 |
Astronomo RD, Kaltgrad E, Udit AK, Wang SK, Doores KJ, Huang CY, Pantophlet R, Paulson JC, Wong CH, Finn MG, Burton DR. Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds. Chemistry & Biology. 17: 357-70. PMID 20416507 DOI: 10.1016/J.Chembiol.2010.03.012 |
0.803 |
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| 2010 |
Astronomo RD, Burton DR. Carbohydrate vaccines: developing sweet solutions to sticky situations? Nature Reviews. Drug Discovery. 9: 308-24. PMID 20357803 DOI: 10.1038/Nrd3012 |
0.73 |
|
| 2010 |
Shedlock DJ, Bailey MA, Popernack PM, Cunningham JM, Burton DR, Sullivan NJ. Antibody-mediated neutralization of Ebola virus can occur by two distinct mechanisms. Virology. 401: 228-35. PMID 20304456 DOI: 10.1016/j.virol.2010.02.029 |
0.424 |
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| 2010 |
Walker LM, Burton DR. Rational antibody-based HIV-1 vaccine design: current approaches and future directions. Current Opinion in Immunology. 22: 358-66. PMID 20299194 DOI: 10.1016/j.coi.2010.02.012 |
0.542 |
|
| 2010 |
Scherer EM, Leaman DP, Zwick MB, McMichael AJ, Burton DR. Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions Proceedings of the National Academy of Sciences of the United States of America. 107: 1529-1534. PMID 20080706 DOI: 10.1073/Pnas.0909680107 |
0.744 |
|
| 2010 |
Hessell AJ, Rakasz EG, Tehrani DM, Huber M, Weisgrau KL, Landucci G, Forthal DN, Koff WC, Poignard P, Watkins DI, Burton DR. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. Journal of Virology. 84: 1302-13. PMID 19906907 DOI: 10.1128/Jvi.01272-09 |
0.437 |
|
| 2009 |
Chen L, Kwon YD, Zhou T, Wu X, O'Dell S, Cavacini L, Hessell AJ, Pancera M, Tang M, Xu L, Yang ZY, Zhang MY, Arthos J, Burton DR, Dimitrov DS, et al. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science (New York, N.Y.). 326: 1123-7. PMID 19965434 DOI: 10.1126/Science.1175868 |
0.462 |
|
| 2009 |
Walker LM, Phogat SK, Chan-Hui PY, Wagner D, Phung P, Goss JL, Wrin T, Simek MD, Fling S, Mitcham JL, Lehrman JK, Priddy FH, Olsen OA, Frey SM, Hammond PW, ... ... Burton DR, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science (New York, N.Y.). 326: 285-9. PMID 19729618 DOI: 10.1126/science.1178746 |
0.529 |
|
| 2009 |
Hessell AJ, Poignard P, Hunter M, Hangartner L, Tehrani DM, Bleeker WK, Parren PWHI, Marx PA, Burton DR. Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques Nature Medicine. 15: 951-954. PMID 19525965 DOI: 10.1038/nm.1974 |
0.493 |
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| 2009 |
Stamatatos L, Morris L, Burton DR, Mascola JR. Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine? Nature Medicine. 15: 866-70. PMID 19525964 DOI: 10.1038/Nm.1949 |
0.527 |
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| 2009 |
Pejchal R, Gach JS, Brunel FM, Cardoso RM, Stanfield RL, Dawson PE, Burton DR, Zwick MB, Wilson IA. A conformational switch in human immunodeficiency virus gp41 revealed by the structures of overlapping epitopes recognized by neutralizing antibodies. Journal of Virology. 83: 8451-62. PMID 19515770 DOI: 10.1128/Jvi.00685-09 |
0.47 |
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| 2009 |
Simek MD, Rida W, Priddy FH, Pung P, Carrow E, Laufer DS, Lehrman JK, Boaz M, Tarragona-Fiol T, Miiro G, Birungi J, Pozniak A, McPhee DA, Manigart O, Karita E, ... ... Burton DR, et al. Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm. Journal of Virology. 83: 7337-48. PMID 19439467 DOI: 10.1128/JVI.00110-09 |
0.425 |
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| 2009 |
Hessell AJ, Rakasz EG, Poignard P, Hangartner L, Landucci G, Forthal DN, Koff WC, Watkins DI, Burton DR. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. Plos Pathogens. 5: e1000433. PMID 19436712 DOI: 10.1371/Journal.Ppat.1000433 |
0.543 |
|
| 2009 |
Walker LM, Bowley DR, Burton DR. Efficient recovery of high-affinity antibodies from a single-chain Fab yeast display library. Journal of Molecular Biology. 389: 365-75. PMID 19376130 DOI: 10.1016/j.jmb.2009.04.019 |
0.476 |
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| 2009 |
Parren PW, Burton DR. Immunology. Two-in-one designer antibodies. Science (New York, N.Y.). 323: 1567-8. PMID 19299606 DOI: 10.1126/science.1172253 |
0.328 |
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| 2009 |
Wu L, Zhou T, Yang ZY, Svehla K, O'Dell S, Louder MK, Xu L, Mascola JR, Burton DR, Hoxie JA, Doms RW, Kwong PD, Nabel GJ. Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain. Journal of Virology. 83: 5077-86. PMID 19264769 DOI: 10.1128/Jvi.02600-08 |
0.418 |
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| 2009 |
Bowley DR, Jones TM, Burton DR, Lerner RA. Libraries against libraries for combinatorial selection of replicating antigen-antibody pairs. Proceedings of the National Academy of Sciences of the United States of America. 106: 1380-5. PMID 19139405 DOI: 10.1073/Pnas.0812291106 |
0.378 |
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| 2009 |
Duenas-Decamp MJ, Peters PJ, Burton D, Clapham PR. Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes. Journal of Virology. 83: 2575-2583. PMID 19129457 DOI: 10.1128/Jvi.02133-08 |
0.321 |
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| 2009 |
Dunlop DC, Mansab F, Doores K, Zitzmann N, Smith D, Burton D, Dwek R, Scanlan C. P05-11. Yeast mannan genetics controls the molecular specificity of anti-carbohydrate antibodies cross-reactive to the HIV envelope Retrovirology. 6: P87. DOI: 10.1186/1742-4690-6-S3-P87 |
0.583 |
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| 2009 |
Walker LL, Poignard P, Simek M, Phogat S, Koff W, Burton D. P04-51 LB. The epitopes of two newly identified broad and potent neutralizing antibodies, PG9 and PG16 Retrovirology. 6: 391. DOI: 10.1186/1742-4690-6-S3-P391 |
0.455 |
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| 2009 |
Phogat S, Walker L, Wagner D, Chan-Hui P, Simek M, Phung P, Wrin T, Mitcham J, Investigator P, Kaminsky S, Zamb T, Moyle M, Koff W, Burton D. S021-06 OA. Potent and broad neutralizing antibodies from HIV-1 non-clade B infected donor reveal a new HIV-1 vaccine target Retrovirology. 6: 1-1. DOI: 10.1186/1742-4690-6-S3-O6 |
0.61 |
|
| 2008 |
Pantophlet R, Wang M, Aguilar-Sino RO, Burton DR. The human immunodeficiency virus type 1 envelope spike of primary viruses can suppress antibody access to variable regions. Journal of Virology. 83: 1649-59. PMID 19036813 DOI: 10.1128/JVI.02046-08 |
0.466 |
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| 2008 |
Reynolds MR, Weiler AM, Weisgrau KL, Piaskowski SM, Furlott JR, Weinfurter JT, Kaizu M, Soma T, León EJ, MacNair C, Leaman DP, Zwick MB, Gostick E, Musani SK, Price DA, ... ... Burton DR, et al. Macaques vaccinated with live-attenuated SIV control replication of heterologous virus. The Journal of Experimental Medicine. 205: 2537-50. PMID 18838548 DOI: 10.1084/Jem.20081524 |
0.322 |
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| 2008 |
Dunlop DC, Ulrich A, Appelmelk BJ, Burton DR, Dwek RA, Zitzmann N, Scanlan CN. Antigenic mimicry of the HIV envelope by AIDS-associated pathogens. Aids (London, England). 22: 2214-7. PMID 18832887 DOI: 10.1097/Qad.0B013E328314B5Df |
0.479 |
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| 2008 |
Pantophlet R, Wrin T, Cavacini LA, Robinson JE, Burton DR. Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity. Virology. 381: 251-60. PMID 18822440 DOI: 10.1016/j.virol.2008.08.032 |
0.406 |
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| 2008 |
Cohen C, Forzan M, Sproat B, Pantophlet R, McGowan I, Burton D, James W. An aptamer that neutralizes R5 strains of HIV-1 binds to core residues of gp120 in the CCR5 binding site. Virology. 381: 46-54. PMID 18799178 DOI: 10.1016/J.Virol.2008.08.025 |
0.51 |
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| 2008 |
Pollock S, Dwek RA, Burton DR, Zitzmann N. N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery. Aids (London, England). 22: 1961-9. PMID 18753929 DOI: 10.1097/Qad.0B013E32830Efd96 |
0.331 |
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| 2008 |
Zwick MB, Gach JS, Burton DR. A welcome burst of human antibodies Nature Biotechnology. 26: 886-887. PMID 18688242 DOI: 10.1038/nbt0808-886 |
0.396 |
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| 2008 |
Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC. HIV vaccine research: the way forward. Science (New York, N.Y.). 321: 530-2. PMID 18653883 DOI: 10.1126/Science.1161000 |
0.347 |
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| 2008 |
Lee JE, Fusco ML, Hessell AJ, Oswald WB, Burton DR, Saphire EO. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature. 454: 177-82. PMID 18615077 DOI: 10.1038/Nature07082 |
0.346 |
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| 2008 |
Watkins DI, Burton DR, Kallas EG, Moore JP, Koff WC. Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans. Nature Medicine. 14: 617-21. PMID 18535579 DOI: 10.1038/Nm.F.1759 |
0.362 |
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| 2008 |
Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, et al. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics. Virology. 377: 170-83. PMID 18499210 DOI: 10.1016/J.Virol.2008.04.005 |
0.528 |
|
| 2008 |
Walker BD, Burton DR. Toward an AIDS vaccine. Science (New York, N.Y.). 320: 760-4. PMID 18467582 DOI: 10.1126/science.1152622 |
0.412 |
|
| 2008 |
Astronomo RD, Lee HK, Scanlan CN, Pantophlet R, Huang CY, Wilson IA, Blixt O, Dwek RA, Wong CH, Burton DR. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120. Journal of Virology. 82: 6359-68. PMID 18434393 DOI: 10.1128/Jvi.00293-08 |
0.799 |
|
| 2008 |
Duenas-Decamp MJ, Peters P, Burton D, Clapham PR. Natural resistance of human immunodeficiency virus type 1 to the CD4bs antibody b12 conferred by a glycan and an arginine residue close to the CD4 binding loop. Journal of Virology. 82: 5807-14. PMID 18385254 DOI: 10.1128/JVI.02585-07 |
0.301 |
|
| 2008 |
Scanlan CN, Burton DR, Dwek RA. Making autoantibodies safe. Proceedings of the National Academy of Sciences of the United States of America. 105: 4081-2. PMID 18344326 DOI: 10.1073/Pnas.0801192105 |
0.32 |
|
| 2008 |
Wang SK, Liang PH, Astronomo RD, Hsu TL, Hsieh SL, Burton DR, Wong CH. Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN. Proceedings of the National Academy of Sciences of the United States of America. 105: 3690-5. PMID 18310320 DOI: 10.1073/Pnas.0712326105 |
0.793 |
|
| 2008 |
Selvarajah S, Puffer BA, Lee FH, Zhu P, Li Y, Wyatt R, Roux KH, Doms RW, Burton DR. Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140. Aids Research and Human Retroviruses. 24: 301-14. PMID 18284327 DOI: 10.1089/Aid.2007.0158 |
0.388 |
|
| 2008 |
Menendez A, Calarese DA, Stanfield RL, Chow KC, Scanlan CN, Kunert R, Katinger H, Burton DR, Wilson IA, Scott JK. A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1380-92. PMID 18198210 DOI: 10.1096/Fj.07-8983Com |
0.364 |
|
| 2008 |
Karlsson Hedestam GB, Fouchier RA, Phogat S, Burton DR, Sodroski J, Wyatt RT. The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus. Nature Reviews. Microbiology. 6: 143-55. PMID 18197170 DOI: 10.1038/Nrmicro1819 |
0.444 |
|
| 2008 |
Bell CH, Pantophlet R, Schiefner A, Cavacini LA, Stanfield RL, Burton DR, Wilson IA. Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization. Journal of Molecular Biology. 375: 969-78. PMID 18068724 DOI: 10.1016/J.Jmb.2007.11.013 |
0.439 |
|
| 2008 |
Lee J, Fusco M, Hessell A, Oswald W, Burton D, Saphire E. Structure of the trimeric prefusionEbolavirus GP complexed with an antibody from a human survivor Acta Crystallographica Section a Foundations of Crystallography. 64: C58-C58. DOI: 10.1107/S0108767308098152 |
0.324 |
|
| 2007 |
Scherer EM, Zwick MB, Teyton L, Burton DR. Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity. Aids (London, England). 21: 2131-9. PMID 18090039 DOI: 10.1097/Qad.0B013E3282A4A632 |
0.768 |
|
| 2007 |
Zwick MB, Burton DR. HIV-1 neutralization: Mechanisms and relevance to vaccine design Current Hiv Research. 5: 608-624. PMID 18045117 DOI: 10.2174/157016207782418443 |
0.482 |
|
| 2007 |
Klasse PJ, Burton DR. Antibodies to West Nile virus: a double-edged sword. Cell Host & Microbe. 1: 87-9. PMID 18005685 DOI: 10.1016/J.CHOM.2007.04.001 |
0.4 |
|
| 2007 |
Burton DR, Wilson IA. Immunology: Square-dancing antibodies Science. 317: 1507-1508. PMID 17872431 DOI: 10.1126/Science.1148905 |
0.363 |
|
| 2007 |
Hessell AJ, Hangartner L, Hunter M, Havenith CE, Beurskens FJ, Bakker JM, Lanigan CM, Landucci G, Forthal DN, Parren PW, Marx PA, Burton DR. Fc receptor but not complement binding is important in antibody protection against HIV. Nature. 449: 101-4. PMID 17805298 DOI: 10.1038/nature06106 |
0.554 |
|
| 2007 |
Mantis NJ, Palaia J, Hessell AJ, Mehta S, Zhu Z, Corthésy B, Neutra MR, Burton DR, Janoff EN. Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region. Journal of Immunology (Baltimore, Md. : 1950). 179: 3144-52. PMID 17709529 DOI: 10.4049/Jimmunol.179.5.3144 |
0.414 |
|
| 2007 |
Scanlan CN, Ritchie GE, Baruah K, Crispin M, Harvey DJ, Singer BB, Lucka L, Wormald MR, Wentworth P, Zitzmann N, Rudd PM, Burton DR, Dwek RA. Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralising, HIV-1 specific antibody. Journal of Molecular Biology. 372: 16-22. PMID 17631311 DOI: 10.1016/J.Jmb.2007.06.027 |
0.518 |
|
| 2007 |
Crooks ET, Moore PL, Franti M, Cayanan CS, Zhu P, Jiang P, de Vries RP, Wiley C, Zharkikh I, Schülke N, Roux KH, Montefiori DC, Burton DR, Binley JM. A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120. Virology. 366: 245-62. PMID 17580087 DOI: 10.1016/J.Virol.2007.04.033 |
0.488 |
|
| 2007 |
Saphire EO, Montero M, Menendez A, van Houten NE, Irving MB, Pantophlet R, Zwick MB, Parren PW, Burton DR, Scott JK, Wilson IA. Structure of a high-affinity "mimotope" peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies. Journal of Molecular Biology. 369: 696-709. PMID 17445828 DOI: 10.1016/J.Jmb.2007.01.060 |
0.344 |
|
| 2007 |
Pantophlet R, Aguilar-Sino RO, Wrin T, Cavacini LA, Burton DR. Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis. Virology. 364: 441-53. PMID 17418361 DOI: 10.1016/J.VIROL.2007.03.007 |
0.465 |
|
| 2007 |
Dhillon AK, Donners H, Pantophlet R, Johnson WE, Decker JM, Shaw GM, Lee FH, Richman DD, Doms RW, Vanham G, Burton DR. Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors. Journal of Virology. 81: 6548-62. PMID 17409160 DOI: 10.1128/Jvi.02749-06 |
0.55 |
|
| 2007 |
Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature. 445: 732-7. PMID 17301785 DOI: 10.1038/Nature05580 |
0.416 |
|
| 2007 |
Nelson JD, Brunel FM, Jensen R, Crooks ET, Cardoso RM, Wang M, Hessell A, Wilson IA, Binley JM, Dawson PE, Burton DR, Zwick MB. An affinity-enhanced neutralizing antibody against the membrane-proximal external region of human immunodeficiency virus type 1 gp41 recognizes an epitope between those of 2F5 and 4E10. Journal of Virology. 81: 4033-43. PMID 17287272 DOI: 10.1128/Jvi.02588-06 |
0.475 |
|
| 2007 |
Law M, Cardoso RM, Wilson IA, Burton DR. Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy. Journal of Virology. 81: 4272-85. PMID 17267498 DOI: 10.1128/Jvi.02536-06 |
0.451 |
|
| 2007 |
Bowley DR, Labrijn AF, Zwick MB, Burton DR. Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage Protein Engineering, Design and Selection. 20: 81-90. PMID 17242026 DOI: 10.1093/protein/gzl057 |
0.467 |
|
| 2007 |
Oswald WB, Geisbert TW, Davis KJ, Geisbert JB, Sullivan NJ, Jahrling PB, Parren PW, Burton DR. Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys. Plos Pathogens. 3: e9. PMID 17238286 DOI: 10.1371/Journal.Ppat.0030009 |
0.372 |
|
| 2007 |
Cardoso RM, Brunel FM, Ferguson S, Zwick M, Burton DR, Dawson PE, Wilson IA. Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10. Journal of Molecular Biology. 365: 1533-44. PMID 17125793 DOI: 10.1016/J.Jmb.2006.10.088 |
0.309 |
|
| 2007 |
Binley JM, Ngo-Abdalla S, Moore P, Bobardt M, Chatterji U, Gallay P, Burton DR, Wilson IA, Elder JH, de Parseval A. Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120 Retrovirology. 4: 23. DOI: 10.1186/1742-4690-4-23 |
0.497 |
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| 2006 |
Binley JM, Ngo-Abdalla S, Moore P, Bobardt M, Chatterji U, Gallay P, Burton DR, Wilson IA, Elder JH, de Parseval A. Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120. Retrovirology. 3: 39. PMID 16817962 DOI: 10.1186/1742-4690-3-39 |
0.469 |
|
| 2006 |
Wilson NA, Reed J, Napoe GS, Piaskowski S, Szymanski A, Furlott J, Gonzalez EJ, Yant LJ, Maness NJ, May GE, Soma T, Reynolds MR, Rakasz E, Rudersdorf R, McDermott AB, ... ... Burton DR, et al. Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239. Journal of Virology. 80: 5875-85. PMID 16731926 DOI: 10.1128/Jvi.00171-06 |
0.37 |
|
| 2006 |
Pantophlet R, Burton DR. GP120: target for neutralizing HIV-1 antibodies. Annual Review of Immunology. 24: 739-69. PMID 16551265 DOI: 10.1146/ANNUREV.IMMUNOL.24.021605.090557 |
0.549 |
|
| 2006 |
O'Connor DH, Burton DR. Immune responses and HIV: a little order from the chaos. The Journal of Experimental Medicine. 203: 501-3. PMID 16533889 DOI: 10.1084/jem.20060216 |
0.421 |
|
| 2006 |
Yuste E, Sanford HB, Carmody J, Bixby J, Little S, Zwick MB, Greenough T, Burton DR, Richman DD, Desrosiers RC, Johnson WE. Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma. Journal of Virology. 80: 3030-41. PMID 16501112 DOI: 10.1128/Jvi.80.6.3030-3041.2006 |
0.466 |
|
| 2006 |
Moore PL, Crooks ET, Porter L, Zhu P, Cayanan CS, Grise H, Corcoran P, Zwick MB, Franti M, Morris L, Roux KH, Burton DR, Binley JM. Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. Journal of Virology. 80: 2515-28. PMID 16474158 DOI: 10.1128/Jvi.80.5.2515-2528.2006 |
0.524 |
|
| 2006 |
Brunel FM, Zwick MB, Cardoso RM, Nelson JD, Wilson IA, Burton DR, Dawson PE. Structure-function analysis of the epitope for 4E10, a broadly neutralizing human immunodeficiency virus type 1 antibody. Journal of Virology. 80: 1680-7. PMID 16439525 DOI: 10.1128/Jvi.80.4.1680-1687.2006 |
0.377 |
|
| 2006 |
Scanlan C, Calarese D, Lee HK, Blixt O, Wong CH, Wilson I, Burton D, Dwek R, Rudd P. Antibody recognition of a carbohydrate epitope: a template for HIV vaccine design. Advances in Experimental Medicine and Biology. 564: 7-8. PMID 16400800 DOI: 10.1007/0-387-25515-X_4 |
0.594 |
|
| 2006 |
Koff WC, Johnson PR, Watkins DI, Burton DR, Lifson JD, Hasenkrug KJ, McDermott AB, Schultz A, Zamb TJ, Boyle R, Desrosiers RC. HIV vaccine design: insights from live attenuated SIV vaccines. Nature Immunology. 7: 19-23. PMID 16357854 DOI: 10.1038/Ni1296 |
0.34 |
|
| 2006 |
Venturini S, Allicotti G, Zhao Y, Simon R, Burton DR, Pinilla C, Poignard P. Identification of peptides from human pathogens able to cross-activate an HIV-1-gag-specific CD4+ T cell clone. European Journal of Immunology. 36: 27-36. PMID 16323241 DOI: 10.1002/EJI.200425767 |
0.325 |
|
| 2006 |
Zhou T, Xu L, Dey B, Hessell AJ, Majeed S, Van Ryk D, Xiang S, Yang X, Zhang M, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, et al. Retrovirology. 3: S22. DOI: 10.1186/1742-4690-3-S1-S22 |
0.46 |
|
| 2005 |
Burton DR, Stanfield RL, Wilson IA. Antibody vs. HIV in a clash of evolutionary titans. Proceedings of the National Academy of Sciences of the United States of America. 102: 14943-8. PMID 16219699 DOI: 10.1073/Pnas.0505126102 |
0.549 |
|
| 2005 |
Calarese DA, Lee HK, Huang CY, Best MD, Astronomo RD, Stanfield RL, Katinger H, Burton DR, Wong CH, Wilson IA. Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proceedings of the National Academy of Sciences of the United States of America. 102: 13372-7. PMID 16174734 DOI: 10.1073/Pnas.0505763102 |
0.801 |
|
| 2005 |
Selvarajah S, Puffer B, Pantophlet R, Law M, Doms RW, Burton DR. Comparing antigenicity and immunogenicity of engineered gp120. Journal of Virology. 79: 12148-63. PMID 16160142 DOI: 10.1128/Jvi.79.19.12148-12163.2005 |
0.418 |
|
| 2005 |
Koefoed K, Farnaes L, Wang M, Svejgaard A, Burton DR, Ditzel HJ. Molecular characterization of the circulating anti-HIV-1 gp120-specific B cell repertoire using antibody phage display libraries generated from pre-selected HIV-1 gp120 binding PBLs Journal of Immunological Methods. 297: 187-201. PMID 15777942 DOI: 10.1016/J.Jim.2004.12.008 |
0.479 |
|
| 2005 |
Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, Katinger H, Burton DR, Wilson IA. Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity. 22: 163-73. PMID 15723805 DOI: 10.1016/J.Immuni.2004.12.011 |
0.434 |
|
| 2005 |
Zwick MB, Jensen R, Church S, Wang M, Stiegler G, Kunert R, Katinger H, Burton DR. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. Journal of Virology. 79: 1252-61. PMID 15613352 DOI: 10.1128/JVI.79.2.1252-1261.2005 |
0.473 |
|
| 2005 |
Xu L, Du X, Zhang W, Tang S, Soong N, Zwick M, Burton D, Whalen R. 984. Directed Molecular Evolution Generates Novel HIV-1 Envelope Variants That Can Elicit Broadly Neutralizing Antibody Responses in Rabbits Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.528 |
0.58 |
|
| 2004 |
Binley JM, Wrin T, Korber B, Zwick MB, Wang M, Chappey C, Stiegler G, Kunert R, Zolla-Pazner S, Katinger H, Petropoulos CJ, Burton DR. Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies. Journal of Virology. 78: 13232-52. PMID 15542675 DOI: 10.1128/Jvi.78.23.13232-13252.2004 |
0.468 |
|
| 2004 |
Pantophlet R, Wilson IA, Burton DR. Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12. Protein Engineering, Design & Selection : Peds. 17: 749-58. PMID 15542540 DOI: 10.1093/Protein/Gzh085 |
0.471 |
|
| 2004 |
Zhang MY, Xiao X, Sidorov IA, Choudhry V, Cham F, Zhang PF, Bouma P, Zwick M, Choudhary A, Montefiori DC, Broder CC, Burton DR, Quinnan GV, Dimitrov DS. Identification and characterization of a new cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody. Journal of Virology. 78: 9233-42. PMID 15308718 DOI: 10.1128/Jvi.78.17.9233-9242.2004 |
0.476 |
|
| 2004 |
Moore JP, Burton DR. Urgently needed: a filter for the HIV-1 vaccine pipeline. Nature Medicine. 10: 769-71. PMID 15286768 DOI: 10.1038/nm0804-769 |
0.437 |
|
| 2004 |
Bryan MC, Fazio F, Lee HK, Huang CY, Chang A, Best MD, Calarese DA, Blixt O, Paulson JC, Burton D, Wilson IA, Wong CH. Covalent display of oligosaccharide arrays in microtiter plates. Journal of the American Chemical Society. 126: 8640-1. PMID 15250702 DOI: 10.1021/Ja048433F |
0.533 |
|
| 2004 |
Moroncini G, Kanu N, Solforosi L, Abalos G, Telling GC, Head M, Ironside J, Brockes JP, Burton DR, Williamson RA. Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc. Proceedings of the National Academy of Sciences of the United States of America. 101: 10404-9. PMID 15240877 DOI: 10.1073/Pnas.0403522101 |
0.415 |
|
| 2004 |
Woof JM, Burton DR. Human antibody-Fc receptor interactions illuminated by crystal structures. Nature Reviews. Immunology. 4: 89-99. PMID 15040582 DOI: 10.1038/nri1266 |
0.318 |
|
| 2004 |
Zwick MB, Komori HK, Stanfield RL, Church S, Wang M, Parren PW, Kunert R, Katinger H, Wilson IA, Burton DR. The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5. Journal of Virology. 78: 3155-61. PMID 14990736 DOI: 10.1128/Jvi.78.6.3155-3161.2004 |
0.3 |
|
| 2004 |
Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, Moore JP, Nabel GJ, Sodroski J, Wilson IA, Wyatt RT. HIV vaccine design and the neutralizing antibody problem. Nature Immunology. 5: 233-6. PMID 14985706 DOI: 10.1038/Ni0304-233 |
0.491 |
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| 2004 |
Lee HK, Scanlan CN, Huang CY, Chang AY, Calarese DA, Dwek RA, Rudd PM, Burton DR, Wilson IA, Wong CH. Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody. Angewandte Chemie (International Ed. in English). 43: 1000-3. PMID 14966891 DOI: 10.1002/Anie.200353105 |
0.511 |
|
| 2004 |
Darbha R, Phogat S, Labrijn AF, Shu Y, Gu Y, Andrykovitch M, Zhang MY, Pantophlet R, Martin L, Vita C, Burton DR, Dimitrov DS, Ji X. Crystal structure of the broadly cross-reactive HIV-1-neutralizing Fab X5 and fine mapping of its epitope. Biochemistry. 43: 1410-7. PMID 14769016 DOI: 10.1021/BI035323X |
0.317 |
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| 2004 |
Burton DR, Desrosiers RC, Doms RW, Feinberg MB, Gallo RC, Hahn B, Hoxie JA, Hunter E, Korber B, Landay A, Lederman MM, Lieberman J, McCune JM, Moore JP, Nathanson N, et al. Public health. A sound rationale needed for phase III HIV-1 vaccine trials. Science (New York, N.Y.). 303: 316. PMID 14726576 DOI: 10.1126/Science.1094620 |
0.303 |
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| 2004 |
Pantophlet R, Burton DR. Immunofocusing: antigen engineering to promote the induction of HIV-neutralizing antibodies. Trends in Molecular Medicine. 9: 468-73. PMID 14604823 DOI: 10.1016/J.MOLMED.2003.09.001 |
0.55 |
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| 2004 |
Lee H, Scanlan CN, Huang C, Chang AY, Calarese DA, Dwek RA, Rudd PM, Burton DR, Wilson IA, Wong C. Reactivity-Based One-Pot Synthesis of Oligomannoses: Defining Antigens Recognized by 2G12, a Broadly Neutralizing anti-HIV-1 Antibody. Cheminform. 35. DOI: 10.1002/CHIN.200418206 |
0.511 |
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| 2003 |
Scanlan CN, Pantophlet R, Wormald MR, Saphire EO, Calarese D, Stanfield R, Wilson IA, Katinger H, Dwek RA, Burton DR, Rudd PM. The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12. Advances in Experimental Medicine and Biology. 535: 205-18. PMID 14714897 DOI: 10.1007/978-1-4615-0065-0_13 |
0.448 |
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| 2003 |
Saphire EO, Stanfield RL, Crispin MD, Morris G, Zwick MB, Pantophlet RA, Parren PW, Rudd PM, Dwek RA, Burton DR, Wilson IA. Crystal structure of an intact human IgG: antibody asymmetry, flexibility, and a guide for HIV-1 vaccine design. Advances in Experimental Medicine and Biology. 535: 55-66. PMID 14714888 DOI: 10.1007/978-1-4615-0065-0_4 |
0.402 |
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| 2003 |
Labrijn AF, Poignard P, Raja A, Zwick MB, Delgado K, Franti M, Binley J, Vivona V, Grundner C, Huang CC, Venturi M, Petropoulos CJ, Wrin T, Dimitrov DS, Robinson J, ... ... Burton DR, et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. Journal of Virology. 77: 10557-65. PMID 12970440 DOI: 10.1128/Jvi.77.19.10557-10565.2003 |
0.544 |
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| 2003 |
Mascola JR, Lewis MG, VanCott TC, Stiegler G, Katinger H, Seaman M, Beaudry K, Barouch DH, Korioth-Schmitz B, Krivulka G, Sambor A, Welcher B, Douek DC, Montefiori DC, Shiver JW, ... ... Burton DR, et al. Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies. Journal of Virology. 77: 10348-56. PMID 12970419 DOI: 10.1128/JVI.77.19.10348-10356.2003 |
0.438 |
|
| 2003 |
Johnson WE, Sanford H, Schwall L, Burton DR, Parren PW, Robinson JE, Desrosiers RC. Assorted mutations in the envelope gene of simian immunodeficiency virus lead to loss of neutralization resistance against antibodies representing a broad spectrum of specificities. Journal of Virology. 77: 9993-10003. PMID 12941910 DOI: 10.1128/Jvi.77.18.9993-10003.2003 |
0.457 |
|
| 2003 |
Choe H, Li W, Wright PL, Vasilieva N, Venturi M, Huang CC, Grundner C, Dorfman T, Zwick MB, Wang L, Rosenberg ES, Kwong PD, Burton DR, Robinson JE, Sodroski JG, et al. Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120. Cell. 114: 161-70. PMID 12887918 DOI: 10.1016/S0092-8674(03)00508-7 |
0.489 |
|
| 2003 |
Calarese DA, Scanlan CN, Zwick MB, Deechongkit S, Mimura Y, Kunert R, Zhu P, Wormald MR, Stanfield RL, Roux KH, Kelly JW, Rudd PM, Dwek RA, Katinger H, Burton DR, et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science (New York, N.Y.). 300: 2065-71. PMID 12829775 DOI: 10.1126/Science.1083182 |
0.466 |
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| 2003 |
Zwick MB, Kelleher R, Jensen R, Labrijn AF, Wang M, Quinnan GV, Parren PW, Burton DR. A novel human antibody against human immunodeficiency virus type 1 gp120 is V1, V2, and V3 loop dependent and helps delimit the epitope of the broadly neutralizing antibody immunoglobulin G1 b12. Journal of Virology. 77: 6965-78. PMID 12768015 DOI: 10.1128/Jvi.77.12.6965-6978.2003 |
0.45 |
|
| 2003 |
Pantophlet R, Wilson IA, Burton DR. Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design. Journal of Virology. 77: 5889-901. PMID 12719582 DOI: 10.1128/Jvi.77.10.5889-5901.2003 |
0.519 |
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| 2003 |
Zwick MB, Parren PW, Saphire EO, Church S, Wang M, Scott JK, Dawson PE, Wilson IA, Burton DR. Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120. Journal of Virology. 77: 5863-76. PMID 12719580 DOI: 10.1128/Jvi.77.10.5863-5876.2003 |
0.347 |
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| 2003 |
Binley JM, Cayanan CS, Wiley C, Schülke N, Olson WC, Burton DR. Redox-triggered infection by disulfide-shackled human immunodeficiency virus type 1 pseudovirions Journal of Virology. 77: 5678-5684. PMID 12719560 DOI: 10.1128/JVI.77.10.5678-5684.2003 |
0.402 |
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| 2003 |
Veazey RS, Shattock RJ, Pope M, Kirijan JC, Jones J, Hu Q, Ketas T, Marx PA, Klasse PJ, Burton DR, Moore JP. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nature Medicine. 9: 343-6. PMID 12579198 DOI: 10.1038/nm833 |
0.369 |
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| 2003 |
Herrera C, Spenlehauer C, Fung MS, Burton DR, Beddows S, Moore JP. Nonneutralizing antibodies to the CD4-binding site on the gp120 subunit of human immunodeficiency virus type 1 do not interfere with the activity of a neutralizing antibody against the same site. Journal of Virology. 77: 1084-91. PMID 12502824 DOI: 10.1128/JVI.77.2.1084-1091.2003 |
0.465 |
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| 2003 |
Pantophlet R, Ollmann Saphire E, Poignard P, Parren PW, Wilson IA, Burton DR. Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120. Journal of Virology. 77: 642-58. PMID 12477867 DOI: 10.1128/Jvi.77.1.642-658.2003 |
0.355 |
|
| 2003 |
Poignard P, Moulard M, Golez E, Vivona V, Franti M, Venturini S, Wang M, Parren PW, Burton DR. Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies. Journal of Virology. 77: 353-65. PMID 12477840 DOI: 10.1128/JVI.77.1.353-365.2003 |
0.467 |
|
| 2002 |
Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PWIH, Robinson J, Van Ryk D, Wang L, ... Burton DR, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature. 420: 678-682. PMID 12478295 DOI: 10.1038/Nature01188 |
0.444 |
|
| 2002 |
Meissner F, Maruyama T, Frentsch M, Hessell AJ, Rodriguez LL, Geisbert TW, Jahrling PB, Burton DR, Parren PWHI. Detection of antibodies against the four subtypes of ebola virus in Sera from any species using a novel antibody-phage indicator assay Virology. 300: 236-243. PMID 12350354 DOI: 10.1006/Viro.2002.1533 |
0.374 |
|
| 2002 |
Burton DR. Antibodies, viruses and vaccines. Nature Reviews. Immunology. 2: 706-13. PMID 12209139 DOI: 10.1038/nri891 |
0.498 |
|
| 2002 |
Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, Burton DR. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120. Journal of Virology. 76: 7306-21. PMID 12072529 DOI: 10.1128/Jvi.76.14.7306-7321.2002 |
0.361 |
|
| 2002 |
Venturini S, Mosier DE, Burton DR, Poignard P. Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization. Journal of Virology. 76: 6987-99. PMID 12072499 DOI: 10.1128/JVI.76.14.6987-6999.2002 |
0.348 |
|
| 2002 |
Parren PWHI, Geisbert TW, Maruyama T, Jahrling PB, Burton DR. Pre- and postexposure prophylaxis of ebola virus infection in an animal model by passive transfer of a neutralizing human antibody Journal of Virology. 76: 6408-6412. PMID 12021376 DOI: 10.1128/Jvi.76.12.6408-6412.2002 |
0.36 |
|
| 2002 |
Moulard M, Phogat SK, Shu Y, Labrijn AF, Xiao X, Binley JM, Zhang MY, Sidorov IA, Broder CC, Robinson J, Parren PW, Burton DR, Dimitrov DS. Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 6913-8. PMID 11997472 DOI: 10.1073/pnas.102562599 |
0.476 |
|
| 2002 |
De Carvalho Nicacio C, Williamson AR, Parren PWHI, Lundkvist A, Burton DR, Björling E. Neutralizing human Fab fragments against measles virus recovered by phage display Journal of Virology. 76: 251-258. PMID 11739690 DOI: 10.1128/JVI.76.1.251-258.2002 |
0.314 |
|
| 2001 |
Zwick MB, Wang M, Poignard P, Stiegler G, Katinger H, Burton DR, Parren PWHI. Neutralization synergy of human immunodeficiency virus type 1 primary isolates by cocktails of broadly neutralizing antibodies Journal of Virology. 75: 12198-12208. PMID 11711611 DOI: 10.1128/JVI.75.24.12198-12208.2001 |
0.541 |
|
| 2001 |
Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, Moore JP, Stiegler G, Katinger H, Burton DR, Parren PW. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. Journal of Virology. 75: 10892-905. PMID 11602729 DOI: 10.1128/Jvi.75.22.10892-10905.2001 |
0.56 |
|
| 2001 |
Peretz D, Williamson RA, Kaneko K, Vergara J, Leclerc E, Schmitt-Ulms G, Mehlhorn IR, Legname G, Wormald MR, Rudd PM, Dwek RA, Burton DR, Prusiner SB. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature. 412: 739-43. PMID 11507642 DOI: 10.1038/35089090 |
0.351 |
|
| 2001 |
Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, Rudd PM, Dwek RA, Stanfield RL, Burton DR, Wilson IA. Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science (New York, N.Y.). 293: 1155-9. PMID 11498595 DOI: 10.1126/Science.1061692 |
0.504 |
|
| 2001 |
Parren PW, Marx PA, Hessell AJ, Luckay A, Harouse J, Cheng-Mayer C, Moore JP, Burton DR. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. Journal of Virology. 75: 8340-7. PMID 11483779 DOI: 10.1128/JVI.75.17.8340-8347.2001 |
0.417 |
|
| 2001 |
Zwick MB, Bonnycastle LL, Menendez A, Irving MB, Barbas CF, Parren PW, Burton DR, Scott JK. Identification and characterization of a peptide that specifically binds the human, broadly neutralizing anti-human immunodeficiency virus type 1 antibody b12. Journal of Virology. 75: 6692-9. PMID 11413337 DOI: 10.1128/Jvi.75.14.6692-6699.2001 |
0.329 |
|
| 2001 |
Moore JP, Parren PW, Burton DR. Genetic subtypes, humoral immunity, and human immunodeficiency virus type 1 vaccine development. Journal of Virology. 75: 5721-9. PMID 11390574 DOI: 10.1128/JVI.75.13.5721-5729.2001 |
0.31 |
|
| 2001 |
Bugli F, Bastidas R, Burton DR, Williamson RA, Clementi M, Burioni R. Molecular profile of a human monoclonal antibody Fab fragment specific for Epstein-Barr virus gp350/220 antigen. Human Immunology. 62: 362-7. PMID 11295468 DOI: 10.1016/S0198-8859(01)00216-6 |
0.414 |
|
| 2001 |
Parren PW, Burton DR. The antiviral activity of antibodies in vitro and in vivo. Advances in Immunology. 77: 195-262. PMID 11293117 DOI: 10.1016/S0065-2776(01)77018-6 |
0.311 |
|
| 2001 |
Poignard P, Saphire EO, Parren PW, Burton DR. gp120: Biologic aspects of structural features. Annual Review of Immunology. 19: 253-74. PMID 11244037 DOI: 10.1146/Annurev.Immunol.19.1.253 |
0.455 |
|
| 2001 |
Saphire EO, Parren PW, Barbas CF, Burton DR, Wilson IA. Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1. Acta Crystallographica. Section D, Biological Crystallography. 57: 168-71. PMID 11134947 DOI: 10.1107/S0907444900017376 |
0.41 |
|
| 2000 |
Ditzel HJ, Masaki Y, Nielsen H, Farnaes L, Burton DR. Cloning and expression of a novel human antibody-antigen pair associated with Felty's syndrome Proceedings of the National Academy of Sciences of the United States of America. 97: 9234-9239. PMID 10922075 DOI: 10.1073/Pnas.97.16.9234 |
0.336 |
|
| 2000 |
Dorrell L, Hessell AJ, Wang M, Whittle H, Sabally S, Rowland-Jones S, Burton DR, Parren PW. Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia. Aids (London, England). 14: 1117-22. PMID 10894275 DOI: 10.1097/00002030-200006160-00008 |
0.452 |
|
| 2000 |
Parren PW, Poignard P, Ditzel HJ, Williamson RA, Burton DR. Antibodies in human infectious disease. Immunologic Research. 21: 265-78. PMID 10852127 DOI: 10.1385/IR:21:2-3:265 |
0.35 |
|
| 2000 |
Burton DR, Parren PW. Vaccines and the induction of functional antibodies: time to look beyond the molecules of natural infection? Nature Medicine. 6: 123-5. PMID 10655088 DOI: 10.1038/72200 |
0.391 |
|
| 2000 |
Wang H, Griffiths MN, Burton DR, Ghazal P. Rapid antibody responses by low-dose, single-step, dendritic cell-targeted immunization. Proceedings of the National Academy of Sciences of the United States of America. 97: 847-52. PMID 10639168 DOI: 10.1073/PNAS.97.2.847 |
0.401 |
|
| 2000 |
Owens GP, Williamson RA, Burgoon MP, Ghausi O, Burton DR, Gilden DH. Cloning the antibody response in humans with chronic inflammatory disease: immunopanning of subacute sclerosing panencephalitis (SSPE) brain sections with antibody phage libraries prepared from SSPE brain enriches for antibody recognizing measles virus antigens in situ. Journal of Virology. 74: 1533-7. PMID 10627565 DOI: 10.1128/Jvi.74.3.1533-1537.2000 |
0.303 |
|
| 1999 |
Kanyo ZF, Pan KM, Williamson RA, Burton DR, Prusiner SB, Fletterick RJ, Cohen FE. Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. Journal of Molecular Biology. 293: 855-63. PMID 10543972 DOI: 10.1006/Jmbi.1999.3193 |
0.311 |
|
| 1999 |
Maruyama T, Rodriguez LL, Jahrling PB, Sanchez A, Khan AS, Nichol ST, Peters CJ, Parren PW, Burton DR. Ebola virus can be effectively neutralized by antibody produced in natural human infection. Journal of Virology. 73: 6024-30. PMID 10364354 DOI: 10.1128/JVI.73.7.6024-6030.1999 |
0.449 |
|
| 1999 |
Poignard P, Sabbe R, Picchio GR, Wang M, Gulizia RJ, Katinger H, Parren PW, Mosier DE, Burton DR. Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo. Immunity. 10: 431-8. PMID 10229186 DOI: 10.1016/S1074-7613(00)80043-6 |
0.466 |
|
| 1999 |
Sakurai H, Williamson RA, Crowe JE, Beeler JA, Poignard P, Bastidas RB, Chanock RM, Burton DR. Human antibody responses to mature and immature forms of viral envelope in respiratory syncytial virus infection: significance for subunit vaccines. Journal of Virology. 73: 2956-62. PMID 10074145 DOI: 10.1128/JVI.73.4.2956-2962.1999 |
0.354 |
|
| 1999 |
Maruyama T, Parren PW, Sanchez A, Rensink I, Rodriguez LL, Khan AS, Peters CJ, Burton DR. Recombinant human monoclonal antibodies to Ebola virus. The Journal of Infectious Diseases. 179: S235-9. PMID 9988189 DOI: 10.1086/514280 |
0.303 |
|
| 1999 |
Moore JP, Burton DR. HIV-1 neutralizing antibodies: how full is the bottle? Nature Medicine. 5: 142-4. PMID 9930854 DOI: 10.1038/5502 |
0.476 |
|
| 1999 |
Crawford JM, Earl PL, Moss B, Reimann KA, Wyand MS, Manson KH, Bilska M, Zhou JT, Pauza CD, Parren PWHI, Burton DR, Sodroski JG, Letvin NL, Montefiori DC. Characterization of Primary Isolate-Like Variants of Simian-Human Immunodeficiency Virus Journal of Virology. 73: 10199-10207. DOI: 10.1128/jvi.73.12.10199-10207.1999 |
0.474 |
|
| 1998 |
Crowe JE, Firestone CY, Crim R, Beeler JA, Coelingh KL, Barbas CF, Burton DR, Chanock RM, Murphy BR. Monoclonal antibody-resistant mutants selected with a respiratory syncytial virus-neutralizing human antibody fab fragment (Fab 19) define a unique epitope on the fusion (F) glycoprotein. Virology. 252: 373-5. PMID 9878616 DOI: 10.1006/Viro.1998.9462 |
0.373 |
|
| 1998 |
Parren PW, Wang M, Trkola A, Binley JM, Purtscher M, Katinger H, Moore JP, Burton DR. Antibody neutralization-resistant primary isolates of human immunodeficiency virus type 1. Journal of Virology. 72: 10270-4. PMID 9811774 DOI: 10.1128/JVI.72.12.10270-10274.1998 |
0.459 |
|
| 1998 |
Williamson RA, Peretz D, Pinilla C, Ball H, Bastidas RB, Rozenshteyn R, Houghten RA, Prusiner SB, Burton DR. Mapping the prion protein using recombinant antibodies. Journal of Virology. 72: 9413-8. PMID 9765500 DOI: 10.1128/JVI.72.11.9413-9418.1998 |
0.339 |
|
| 1998 |
Agosto M, Allan J, Benson C, Berger EA, Blumenthal R, Burton D, Clements J, Coffin J, Connor R, Cullen B, Desrosiers R, Dimitrov D, Doms R, Emerman M, Feinberg M, et al. AIDS vaccine development. Science (New York, N.Y.). 280: 803, 804-5. PMID 9599148 DOI: 10.1126/Science.280.5365.803C |
0.453 |
|
| 1998 |
Burton DR, Moore JP. Why do we not have an HIV vaccine and how can we make one? . Nature Medicine. 4: 495-8. PMID 9585194 DOI: 10.1038/NM0598SUPP-495 |
0.391 |
|
| 1998 |
Salonen EM, Parren PW, Graus YF, Lundkvist A, Fisicaro P, Vapalahti O, Kallio-Kokko H, Vaheri A, Burton DR. Human recombinant Puumala virus antibodies: cross-reaction with other hantaviruses and use in diagnostics. The Journal of General Virology. 659-65. PMID 9568958 DOI: 10.1099/0022-1317-79-4-659 |
0.383 |
|
| 1998 |
Ditzel HJ, Rosenkilde MM, Garred P, Wang M, Koefoed K, Pedersen C, Burton DR, Schwartz TW. The CCR5 receptor acts as an alloantigen in CCR5Delta32 homozygous individuals: identification of chemokineand HIV-1-blocking human antibodies. Proceedings of the National Academy of Sciences of the United States of America. 95: 5241-5. PMID 9560260 DOI: 10.1073/PNAS.95.9.5241 |
0.343 |
|
| 1998 |
Parren PW, Mondor I, Naniche D, Ditzel HJ, Klasse PJ, Burton DR, Sattentau QJ. Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity. Journal of Virology. 72: 3512-9. PMID 9557629 DOI: 10.1128/JVI.72.5.3512-3519.1998 |
0.513 |
|
| 1998 |
Glamann J, Burton DR, Parren PWHI, Ditzel HJ, Kent KA, Arnold C, Montefiori D, Hirsch VM. Simian immunodeficiency virus (SIV) envelope-specific Fabs with high- level homologous neutralizing activity: Recovery from a long-term- nonprogressor SIV-infected macaque Journal of Virology. 72: 585-592. PMID 9420262 DOI: 10.1128/JVI.72.1.585-592.1998 |
0.382 |
|
| 1998 |
Gauduin MC, Parren PW, Weir R, Barbas CF, Burton DR, Koup RA. Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1. Nature Medicine. 3: 1389-93. PMID 9396610 DOI: 10.1038/NM1297-1389 |
0.51 |
|
| 1998 |
Moreno de Alborán I, Martínéz-alonso C, Barbas CF, Burton DR, Ditzel HJ. Human monoclonal Fab fragments specific for viral antigens from combinatorial IgA libraries. Immunotechnology : An International Journal of Immunological Engineering. 1: 21-8. PMID 9373330 DOI: 10.1016/1380-2933(95)00002-X |
0.362 |
|
| 1998 |
Sullivan N, Sun Y, Binley J, Lee J, Barbas CF, Parren PWHI, Burton DR, Sodroski J. Determinants of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Activation by Soluble CD4 and Monoclonal Antibodies Journal of Virology. 72: 6332-6338. DOI: 10.1128/jvi.72.8.6332-6338.1998 |
0.437 |
|
| 1998 |
Frankel SS, Steinman RM, Michael NL, Kim SR, Bhardwaj N, Pope M, Louder MK, Ehrenberg PK, Parren PWHI, Burton DR, Katinger H, VanCott TC, Robb ML, Birx DL, Mascola JR. Neutralizing Monoclonal Antibodies Block Human Immunodeficiency Virus Type 1 Infection of Dendritic Cells and Transmission to T Cells Journal of Virology. 72: 9788-9794. DOI: 10.1128/jvi.72.12.9788-9794.1998 |
0.415 |
|
| 1997 |
Burton DR. A vaccine for HIV type 1: the antibody perspective. Proceedings of the National Academy of Sciences of the United States of America. 94: 10018-23. PMID 9294155 DOI: 10.1073/PNAS.94.19.10018 |
0.572 |
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| 1997 |
Parren PW, Gauduin MC, Koup RA, Poignard P, Sattentau QJ, Fisicaro P, Burton DR. Erratum to "Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design". Immunology Letters. 58: 125-32. PMID 9271324 DOI: 10.1016/S0165-2478(97)00109-0 |
0.567 |
|
| 1997 |
Mo H, Stamatatos L, Ip JE, Barbas CF, Parren PW, Burton DR, Moore JP, Ho DD. Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody IgG1b12. off. Journal of Virology. 71: 6869-74. PMID 9261412 DOI: 10.1128/Jvi.71.9.6869-6874.1997 |
0.409 |
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| 1997 |
Parren PW, Gauduin MC, Koup RA, Poignard P, Fisicaro P, Burton DR, Sattentau QJ. Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design. Immunology Letters. 57: 105-12. PMID 9232434 DOI: 10.1016/S0165-2478(97)00043-6 |
0.567 |
|
| 1997 |
Graus YF, de Baets MH, van Breda Vriesman PJ, Burton DR. Anti-acetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies. Immunology Letters. 57: 59-62. PMID 9232426 DOI: 10.1016/S0165-2478(97)00046-1 |
0.332 |
|
| 1997 |
Li AN, Baba TW, Sodroski J, Zolla-Pazner S, Gorny MK, Robinson J, Posner MR, Katinger H, Barbas CF, Burton DR, Chou TC, Ruprecht RM. Synergistic neutralization of a chimetic SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins Aids Research and Human Retroviruses. 13: 647-656. PMID 9168233 DOI: 10.1089/Aid.1997.13.647 |
0.521 |
|
| 1997 |
Cattani P, Rossolini GM, Cresti S, Santangelo R, Burton DR, Williamson RA, Sanna PP, Fadda G. Detection and typing of herpes simplex viruses by using recombinant immunoglobulin fragments produced in bacteria. Journal of Clinical Microbiology. 35: 1504-9. PMID 9163470 DOI: 10.1128/jcm.35.6.1504-1509.1997 |
0.306 |
|
| 1997 |
Kessler JA, McKenna PM, Emini EA, Chan CP, Patel MD, Gupta SK, Mark GE, Barbas CF, Burton DR, Conley AJ. Recombinant human monoclonal antibody IgG1b12 neutralizes diverse human immunodeficiency virus type 1 primary isolates. Aids Research and Human Retroviruses. 13: 575-82. PMID 9135875 |
0.475 |
|
| 1997 |
Ditzel HJ, Parren PW, Binley JM, Sodroski J, Moore JP, Barbas CF, Burton DR. Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries. Journal of Molecular Biology. 267: 684-95. PMID 9126846 DOI: 10.1006/Jmbi.1997.0912 |
0.447 |
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| 1997 |
Parren PW, Burton DR, Sattentau QJ. HIV-1 antibody--debris or virion? Nature Medicine. 3: 366-7. PMID 9095159 DOI: 10.1038/nm0497-366d |
0.469 |
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| 1997 |
Parren PW, Fisicaro P, Labrijn AF, Binley JM, Yang WP, Ditzel HJ, Barbas CF, Burton DR. In vitro antigen challenge of human antibody libraries for vaccine evaluation: the human immunodeficiency virus type 1 envelope. Journal of Virology. 70: 9046-50. PMID 8971041 DOI: 10.1128/jvi.70.12.9046-9050.1996 |
0.48 |
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| 1997 |
Parren PW, Sattenau QJ, Burton DR. Importance of anti-HIV-1 antibodies Nature Medicine. 3: 591-591. DOI: 10.1038/nm0697-591a |
0.461 |
|
| 1997 |
Graus Y, De Baets M, van Breda Vriesman P, Burton D. Fab fragments isolated from thymus of myasthenia gravis patients reflect predominant specificities in serum and block the action of serum antibodies Immunology Letters. 56: 369-370. DOI: 10.1016/S0165-2478(97)86492-9 |
0.372 |
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| 1997 |
Parren PW, Fisicaro P, Barbas CF, Poignard P, Burton DR. Characterization of the antibody response to HIV-1 envelope Immunology Letters. 56: 192. DOI: 10.1016/s0165-2478(97)85770-7 |
0.452 |
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| 1996 |
Zeitlin L, Whaley KJ, Sanna PP, Moench TR, Bastidas R, De Logu A, Williamson RA, Burton DR, Cone RA. Topically applied human recombinant monoclonal IgG1 antibody and its Fab and F(ab')2 fragments protect mice from vaginal transmission of HSV-2. Virology. 225: 213-5. PMID 8918548 DOI: 10.1006/viro.1996.0589 |
0.32 |
|
| 1996 |
Seligman SJ, Binley JM, Gorny MK, Burton DR, Zolla-Pazner S, Sokolowski KA. Characterization by serial deletion competition ELISAs of HIV-1 V3 loop epitopes recognized by monoclonal antibodies. Molecular Immunology. 33: 737-45. PMID 8811069 DOI: 10.1016/0161-5890(96)00044-2 |
0.416 |
|
| 1996 |
Binley JM, Ditzel HJ, Barbas CF, Sullivan N, Sodroski J, Parren PWHI, Burton DR. Human antibody responses to HIV type 1 glycoprotein 41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding Aids Research and Human Retroviruses. 12: 911-924. PMID 8798976 DOI: 10.1089/Aid.1996.12.911 |
0.494 |
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| 1996 |
Barbas CF, Burton DR. Selection and evolution of high-affinity human anti-viral antibodies. Trends in Biotechnology. 14: 230-4. PMID 8771795 DOI: 10.1016/0167-7799(96)10029-9 |
0.486 |
|
| 1996 |
Williamson RA, Peretz D, Smorodinsky N, Bastidas R, Serban H, Mehlhorn I, DeArmond SJ, Prusiner SB, Burton DR. Circumventing tolerance to generate autologous monoclonal antibodies to the prion protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 7279-82. PMID 8692983 DOI: 10.1073/pnas.93.14.7279 |
0.302 |
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| 1996 |
Sanna PP, De Logu A, Williamson RA, Hom YL, Straus SE, Bloom FE, Burton DR. Protection of nude mice by passive immunization with a type-common human recombinant monoclonal antibody against HSV. Virology. 215: 101-6. PMID 8553581 DOI: 10.1006/viro.1996.0011 |
0.355 |
|
| 1996 |
Yang WP, Green K, Pinz-Sweeney S, Briones AT, Burton DR, Barbas CF. CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range. Journal of Molecular Biology. 254: 392-403. PMID 7490758 DOI: 10.1006/jmbi.1995.0626 |
0.425 |
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| 1995 |
Sanna PP, De Logu A, Williamson RA, Samson ME, Altieri DC, Bloom FE, Burton DR. Rapid assay of phage-derived recombinant human fabs as bispecific antibodies. Bio/Technology (Nature Publishing Company). 13: 1221-4. PMID 9636296 DOI: 10.1038/nbt1195-1221 |
0.382 |
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| 1995 |
Parren PW, Ditzel HJ, Gulizia RJ, Binley JM, Barbas CF, Burton DR, Mosier DE. Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site. Aids (London, England). 9: F1-6. PMID 7662189 DOI: 10.1097/00002030-199506000-00001 |
0.423 |
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| 1995 |
Sanna PP, Williamson RA, De Logu A, Bloom FE, Burton DR. Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries. Proceedings of the National Academy of Sciences of the United States of America. 92: 6439-43. PMID 7604009 DOI: 10.1073/pnas.92.14.6439 |
0.416 |
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| 1995 |
Moore JP, Cao Y, Qing L, Sattentau QJ, Pyati J, Koduri R, Robinson J, Barbas CF, Burton DR, Ho DD. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. Journal of Virology. 69: 101-9. PMID 7527081 DOI: 10.1128/jvi.69.1.101-109.1995 |
0.426 |
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| 1995 |
Trkola A, Pomales AB, Yuan H, Korber B, Maddon PJ, Allaway GP, Katinger H, Barbas CF, Burton DR, Ho DD. Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG. Journal of Virology. 69: 6609-17. PMID 7474069 DOI: 10.1128/jvi.69.11.6609-6617.1995 |
0.381 |
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| 1994 |
Burioni R, Williamson RA, Sanna PP, Bloom FE, Burton DR. Recombinant human Fab to glycoprotein D neutralizes infectivity and prevents cell-to-cell transmission of herpes simplex viruses 1 and 2 in vitro. Proceedings of the National Academy of Sciences of the United States of America. 91: 355-9. PMID 8278393 DOI: 10.1073/pnas.91.1.355 |
0.33 |
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| 1994 |
Barbas CF, Hu D, Dunlop N, Sawyer L, Cababa D, Hendry RM, Nara PL, Burton DR. In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity. Proceedings of the National Academy of Sciences of the United States of America. 91: 3809-13. PMID 8170992 DOI: 10.1073/pnas.91.9.3809 |
0.425 |
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| 1994 |
Ditzel HJ, Barbas SM, Barbas CF, Burton DR. The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 91: 3710-4. PMID 8170974 DOI: 10.1073/pnas.91.9.3710 |
0.475 |
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| 1994 |
Hexham JM, Partridge LJ, Furmaniak J, Petersen VB, Colls JC, Pegg C, Rees Smith B, Burton DR. Cloning and characterisation of TPO autoantibodies using combinatorial phage display libraries. Autoimmunity. 17: 167-79. PMID 7524700 DOI: 10.3109/08916939409010651 |
0.309 |
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| 1994 |
Roben P, Moore JP, Thali M, Sodroski J, Barbas CF, Burton DR. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1 Journal of Virology. 68: 4821-4828. PMID 7518527 DOI: 10.1128/Jvi.68.8.4821-4828.1994 |
0.449 |
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| 1993 |
Williamson RA, Burioni R, Sanna PP, Partridge LJ, Barbas CF, Burton DR. Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries. Proceedings of the National Academy of Sciences of the United States of America. 90: 4141-5. PMID 7683424 DOI: 10.1073/pnas.90.9.4141 |
0.396 |
|
| 1993 |
Burton DR. Monoclonal antibodies from combinatorial libraries Accounts of Chemical Research. 26: 405-411. DOI: 10.1021/ar00032a003 |
0.346 |
|
| 1992 |
Lerner RA, Kang AS, Bain JD, Burton DR, Barbas CF. Antibodies without immunization. Science (New York, N.Y.). 258: 1313-4. PMID 1455226 DOI: 10.1126/Science.1455226 |
0.328 |
|
| 1992 |
Burton DR, Barbas CF. Antibodies from libraries. Nature. 359: 782-3. PMID 1436054 DOI: 10.1038/359782b0 |
0.348 |
|
| 1992 |
Zebedee SL, Barbas CF, Hom YL, Caothien RH, Graff R, DeGraw J, Pyati J, LaPolla R, Burton DR, Lerner RA, Thornton GB. Human combinatorial antibody libraries to hepatitis B surface antigen Proceedings of the National Academy of Sciences of the United States of America. 89: 3175-3179. PMID 1373487 DOI: 10.1073/Pnas.89.8.3175 |
0.364 |
|
| 1992 |
Barbas CF, Crowe JE, Cababa D, Jones TM, Zebedee SL, Murphy BR, Chanock RM, Burton DR. Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity. Proceedings of the National Academy of Sciences of the United States of America. 89: 10164-8. PMID 1279672 DOI: 10.1073/pnas.89.21.10164 |
0.312 |
|
| 1991 |
Persson MA, Caothien RH, Burton DR. Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning. Proceedings of the National Academy of Sciences of the United States of America. 88: 2432-6. PMID 1826052 DOI: 10.1073/pnas.88.6.2432 |
0.341 |
|
| 1991 |
Kang AS, Jones TM, Burton DR. Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries Proceedings of the National Academy of Sciences of the United States of America. 88: 11120-11123. PMID 1763028 DOI: 10.1073/pnas.88.24.11120 |
0.342 |
|
| 1991 |
Burton DR. Human and mouse monoclonal antibodies by repertoire cloning Trends in Biotechnology. 9: 169-175. PMID 1367284 DOI: 10.1016/0167-7799(91)90055-M |
0.369 |
|
| 1990 |
Partridge LJ, Dransfield I, Burton D. Characterization of a monoclonal antibody recognizing a novel leucocyte adhesion molecule. Biochemical Society Transactions. 18: 274-5. PMID 2379714 DOI: 10.1042/Bst0180274A |
0.422 |
|
| 1990 |
Burton DR. Antibody: the flexible adaptor molecule. Trends in Biochemical Sciences. 15: 64-9. PMID 2186517 DOI: 10.1016/0968-0004(90)90178-E |
0.35 |
|
| 1989 |
Burton DR, Jefferis R, Partridge LJ, Woof JM. Molecular recognition of antibody (IgG) by cellular Fc receptor (FcRI). Molecular Immunology. 25: 1175-81. PMID 2975762 DOI: 10.1016/0161-5890(88)90153-8 |
0.359 |
|
| 1988 |
Duncan AR, Woof JM, Partridge LJ, Burton DR, Winter G. Localization of the binding site for the human high-affinity Fc receptor on IgG. Nature. 332: 563-4. PMID 2965792 DOI: 10.1038/332563a0 |
0.334 |
|
| 1988 |
WALKER MR, WOOF JM, BURTON DR, BRÜGGEMANN M, JEFFERIS R. Immunoglobulin G subclass specificity of human Fc receptor II determined using human chimeric anti-5-iodio-4-hydroxy-3-nitrophenacetyl monoclonal antibodies Biochemical Society Transactions. 16: 725-726. DOI: 10.1042/bst0160725 |
0.32 |
|
| 1988 |
DRANSFIELD I, MOIR AJG, SHETH B, BURTON DR, PARTRIDGE LJ. Initial characterization of an anti-actin monoclonal antibody (NH3) Biochemical Society Transactions. 16: 163-164. DOI: 10.1042/bst0160163 |
0.327 |
|
| 1979 |
Burton DR, Forsén S, Franĕk F, Novotný J. Proton relaxation enhancement to probe the effects of antigen binding on pig antibody structure. Febs Letters. 102: 249-52. PMID 88375 DOI: 10.1016/0014-5793(79)80011-3 |
0.352 |
|
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