| Year |
Citation |
Score |
| 2020 |
Kadosh BS, Garshick MS, Gaztanaga J, Moore KJ, Newman JD, Pillinger M, Ramasamy R, Reynolds HR, Shah B, Hochman J, Fishman GI, Katz SD. COVID-19 and the Heart and Vasculature: Novel Approaches to Reduce Virus-Induced Inflammation in Patients With Cardiovascular Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314513. PMID 32687400 DOI: 10.1161/Atvbaha.120.314513 |
0.329 |
|
| 2020 |
Senatus L, López-Díez R, Egaña-Gorroño L, Liu J, Hu J, Daffu G, Li Q, Rahman K, Vengrenyuk Y, Barrett TJ, Dewan MZ, Guo L, Fuller D, Finn AV, Virmani R, ... ... Ramasamy R, et al. RAGE impairs murine diabetic atherosclerosis regression and implicates IRF7 in macrophage inflammation and cholesterol metabolism. Jci Insight. 5. PMID 32641587 DOI: 10.1172/Jci.Insight.137289 |
0.385 |
|
| 2020 |
Egaña-Gorroño L, López-Díez R, Yepuri G, Ramirez LS, Reverdatto S, Gugger PF, Shekhtman A, Ramasamy R, Schmidt AM. Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models. Frontiers in Cardiovascular Medicine. 7: 37. PMID 32211423 DOI: 10.3389/Fcvm.2020.00037 |
0.419 |
|
| 2020 |
Perfetti R, Yepuri G, Quadri NA, Ghannam AF, Ramasamy R, Shendelman S. 1080-P: Addressing the Safety Challenges of Aldose Reductase Inhibition: Development of AT-001 for Diabetic Cardiomyopathy, a Potent and Selective Next Generation Aldose Reductase Inhibitor Diabetes. 69. DOI: 10.2337/Db20-1080-P |
0.33 |
|
| 2020 |
Manigrasso MB, Quadri NA, Frye LE, D’Agati V, DeVita RJ, Ramasamy R, Shekhtman A, Schmidt AM. Novel Therapeutic Opportunities for Diabetic Complications using a Small Molecule Antagonist of RAGE/DIAPH1 Interaction The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03475 |
0.339 |
|
| 2019 |
Ruiz HH, Ramasamy R, Schmidt AM. Advanced Glycation End Products: Building on the Concept of the "Common Soil" in Metabolic Disease. Endocrinology. PMID 31638645 DOI: 10.1210/Endocr/Bqz006 |
0.35 |
|
| 2019 |
Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, et al. A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Reports. 28: 773-791.e7. PMID 31315054 DOI: 10.1016/J.Celrep.2019.06.061 |
0.339 |
|
| 2019 |
Ruiz HH, López Díez R, Arivazahagan L, Ramasamy R, Schmidt AM. Metabolism, Obesity, and Diabetes Mellitus. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: e166-e174. PMID 31242034 DOI: 10.1161/Atvbaha.119.312005 |
0.305 |
|
| 2019 |
Abdulle A, Inman CK, Saleh A, Noshi M, Galani D, Abdelwareth L, Alsafar H, Elfatih A, Al Shamsi H, Ali R, Li H, Ramasamy R, Schmidt AM, Benbarka MM, Hassan MH. Metabolic dysfunction in Emirati subjects in Abu Dhabi: Relationship to levels of soluble RAGEs. Journal of Clinical & Translational Endocrinology. 16: 100192. PMID 31080742 DOI: 10.1016/J.Jcte.2019.100192 |
0.331 |
|
| 2019 |
MacLean M, Derk J, Ruiz HH, Juranek JK, Ramasamy R, Schmidt AM. The Receptor for Advanced Glycation End Products (RAGE) and DIAPH1: Implications for vascular and neuroinflammatory dysfunction in disorders of the central nervous system. Neurochemistry International. PMID 30902646 DOI: 10.1016/J.Neuint.2019.03.012 |
0.353 |
|
| 2019 |
Perfetti R, Rowell P, Shendelman S, Lawson F, Ramasamy R. Preclinical and Clinical Proof of Concept for Metabolic Intervention in Diabetic Cardiomyopathy Journal of Cardiac Failure. 25. DOI: 10.1016/J.Cardfail.2019.07.218 |
0.433 |
|
| 2018 |
Manigrasso MB, Friedman RA, Ramasamy R, D'Agati VD, Schmidt AM. Deletion of the Formin, Diaph1, Protects from Structural and Functional Abnormalities in the Murine Diabetic Kidney. American Journal of Physiology. Renal Physiology. PMID 30132346 DOI: 10.1152/Ajprenal.00075.2018 |
0.382 |
|
| 2018 |
Yuan C, Hu J, Parathath S, Grauer L, Cassella CB, Bagdasarov S, Goldberg IJ, Ramasamy R, Fisher EA. Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice. Diabetes. PMID 29891593 DOI: 10.2337/Db18-0156 |
0.376 |
|
| 2017 |
O'Shea KM, Ananthakrishnan R, Li Q, Quadri N, Thiagarajan D, Sreejit G, Wang L, Zirpoli H, Aranda JF, Alberts AS, Schmidt AM, Ramasamy R. The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury. Ebiomedicine. 26: 165-174. PMID 29239839 DOI: 10.1016/J.Ebiom.2017.11.012 |
0.425 |
|
| 2017 |
Inman CK, Aljunaibi A, Koh H, Abdulle A, Ali R, Alnaeemi A, Al Zaabi E, Oumeziane N, Al Bastaki M, Al-Houqani M, Al-Maskari F, Al Dhaheri A, Shah SM, Abdel Wareth L, Al Mahmeed W, ... ... Ramasamy R, et al. The AGE-RAGE axis in an Arab population: The United Arab Emirates Healthy Futures (UAEHFS) pilot study. Journal of Clinical & Translational Endocrinology. 10: 1-8. PMID 29204365 DOI: 10.1016/J.Jcte.2017.08.001 |
0.334 |
|
| 2017 |
Thiagarajan D, O' Shea K, Sreejit G, Ananthakrishnan R, Quadri N, Li Q, Schmidt AM, Gabbay K, Ramasamy R. Aldose reductase modulates acute activation of mesenchymal markers via the β-catenin pathway during cardiac ischemia-reperfusion. Plos One. 12: e0188981. PMID 29190815 DOI: 10.1371/Journal.Pone.0188981 |
0.431 |
|
| 2016 |
Shekhtman A, Ramasamy R, Schmidt AM. Glycation & the RAGE axis: targeting signal transduction through Diaph1. Expert Review of Proteomics. PMID 27967251 DOI: 10.1080/14789450.2017.1271719 |
0.348 |
|
| 2016 |
Thiagarajan D, Vedantham S, Ananthakrishnan R, Schmidt AM, Ramasamy R. Mechanisms of transcription factor acetylation and consequences in hearts. Biochimica Et Biophysica Acta. PMID 27543804 DOI: 10.1016/J.Bbadis.2016.08.011 |
0.301 |
|
| 2016 |
Diez RL, Shekhtman A, Ramasamy R, Schmidt AM. Cellular mechanisms and consequences of glycation in atherosclerosis and obesity. Biochimica Et Biophysica Acta. PMID 27166197 DOI: 10.1016/J.Bbadis.2016.05.005 |
0.364 |
|
| 2016 |
Thiagarajan D, Ananthakrishnan R, Zhang J, O'Shea KM, Quadri N, Li Q, Sas K, Jing X, Rosario R, Pennathur S, Schmidt AM, Ramasamy R. Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor. Cell Reports. PMID 27052179 DOI: 10.1016/J.Celrep.2016.02.086 |
0.31 |
|
| 2016 |
Manigrasso MB, Pan J, Rai V, Zhang J, Reverdatto S, Quadri N, DeVita RJ, Ramasamy R, Shekhtman A, Schmidt AM. Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction. Scientific Reports. 6: 22450. PMID 26936329 DOI: 10.1038/Srep22450 |
0.346 |
|
| 2015 |
Ramasamy R, Shekhtman A, Schmidt AM. The multiple faces of RAGE - opportunities for therapeutic intervention in aging and chronic disease. Expert Opinion On Therapeutic Targets. 1-16. PMID 26558318 DOI: 10.1517/14728222.2016.1111873 |
0.307 |
|
| 2015 |
Daffu G, Shen X, Senatus L, Thiagarajan D, Abedini A, Hurtado Del Pozo C, Rosario R, Song F, Friedman RA, Ramasamy R, Schmidt AM. RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes. Diabetes. PMID 26253613 DOI: 10.2337/Db15-0575 |
0.351 |
|
| 2015 |
Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Glutaminolysis and Transferrin Regulate Ferroptosis. Molecular Cell. 59: 298-308. PMID 26166707 DOI: 10.1016/J.Molcel.2015.06.011 |
0.357 |
|
| 2015 |
Litwinoff E, Hurtado Del Pozo C, Ramasamy R, Schmidt AM. Emerging Targets for Therapeutic Development in Diabetes and Its Complications: The RAGE Signaling Pathway. Clinical Pharmacology and Therapeutics. PMID 25974754 DOI: 10.1002/Cpt.148 |
0.394 |
|
| 2015 |
Zirpoli H, Abdillahi M, Quadri N, Ananthakrishnan R, Wang L, Rosario R, Zhu Z, Deckelbaum RJ, Ramasamy R. Acute administration of n-3 rich triglyceride emulsions provides cardioprotection in murine models after ischemia-reperfusion. Plos One. 10: e0116274. PMID 25559887 DOI: 10.1371/Journal.Pone.0116274 |
0.73 |
|
| 2014 |
Song F, Hurtado del Pozo C, Rosario R, Zou YS, Ananthakrishnan R, Xu X, Patel PR, Benoit VM, Yan SF, Li H, Friedman RA, Kim JK, Ramasamy R, Ferrante AW, Schmidt AM. RAGE regulates the metabolic and inflammatory response to high-fat feeding in mice. Diabetes. 63: 1948-65. PMID 24520121 DOI: 10.2337/Db13-1636 |
0.308 |
|
| 2014 |
Vedantham S, Thiagarajan D, Ananthakrishnan R, Wang L, Rosario R, Zou YS, Goldberg I, Yan SF, Schmidt AM, Ramasamy R. Aldose reductase drives hyperacetylation of Egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals. Diabetes. 63: 761-74. PMID 24186862 DOI: 10.2337/Db13-0032 |
0.393 |
|
| 2014 |
Manigrasso MB, Juranek J, Ramasamy R, Schmidt AM. Unlocking the biology of RAGE in diabetic microvascular complications. Trends in Endocrinology and Metabolism: Tem. 25: 15-22. PMID 24011512 DOI: 10.1016/J.Tem.2013.08.002 |
0.396 |
|
| 2013 |
Daffu G, del Pozo CH, O'Shea KM, Ananthakrishnan R, Ramasamy R, Schmidt AM. Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond. International Journal of Molecular Sciences. 14: 19891-910. PMID 24084731 DOI: 10.3390/Ijms141019891 |
0.345 |
|
| 2013 |
Ananthakrishnan R, Li Q, O'Shea KM, Quadri N, Wang L, Abuchowski A, Schmidt AM, Ramasamy R. Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice Artificial Cells, Nanomedicine and Biotechnology. 41: 428-436. PMID 23342967 DOI: 10.3109/21691401.2012.762370 |
0.416 |
|
| 2013 |
Bao L, Taskin E, Foster M, Ray B, Rosario R, Ananthakrishnan R, Howlett SE, Schmidt AM, Ramasamy R, Coetzee WA. Alterations in ventricular K(ATP) channel properties during aging. Aging Cell. 12: 167-76. PMID 23173756 DOI: 10.1111/Acel.12033 |
0.303 |
|
| 2012 |
Rai V, Touré F, Chitayat S, Pei R, Song F, Li Q, Zhang J, Rosario R, Ramasamy R, Chazin WJ, Schmidt AM. Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling. The Journal of Experimental Medicine. 209: 2339-50. PMID 23209312 DOI: 10.1084/Jem.20120873 |
0.337 |
|
| 2012 |
Son NH, Ananthakrishnan R, Yu S, Khan RS, Jiang H, Ji R, Akashi H, Li Q, O'Shea K, Homma S, Goldberg IJ, Ramasamy R. Cardiomyocyte aldose reductase causes heart failure and impairs recovery from ischemia. Plos One. 7: e46549. PMID 23029549 DOI: 10.1371/Journal.Pone.0046549 |
0.422 |
|
| 2012 |
Abel ED, O'Shea KM, Ramasamy R. Insulin resistance: Metabolic mechanisms and consequences in the heart Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2068-2076. PMID 22895668 DOI: 10.1161/Atvbaha.111.241984 |
0.338 |
|
| 2012 |
Ramasamy R, Yan SF, Schmidt AM. The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes. Vascular Pharmacology. 57: 160-7. PMID 22750165 DOI: 10.1016/J.Vph.2012.06.004 |
0.404 |
|
| 2012 |
Abdillahi M, Ananthakrishnan R, Vedantham S, Shang L, Zhu Z, Rosario R, Zirpoli H, Bohren KM, Gabbay KH, Ramasamy R. Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 303: H297-308. PMID 22661511 DOI: 10.1152/Ajpheart.00999.2011 |
0.73 |
|
| 2012 |
Vedantham S, Ananthakrishnan R, Schmidt AM, Ramasamy R. Aldose reductase, oxidative stress and diabetic cardiovascular complications. Cardiovascular & Hematological Agents in Medicinal Chemistry. 10: 234-40. PMID 22632267 DOI: 10.2174/187152512802651097 |
0.401 |
|
| 2012 |
Touré F, Fritz G, Li Q, Rai V, Daffu G, Zou YS, Rosario R, Ramasamy R, Alberts AS, Yan SF, Schmidt AM. Formin mDia1 mediates vascular remodeling via integration of oxidative and signal transduction pathways. Circulation Research. 110: 1279-93. PMID 22511750 DOI: 10.1161/Circresaha.111.262519 |
0.305 |
|
| 2012 |
Ramasamy R, Schmidt AM. Receptor for advanced glycation end products (RAGE) and implications for the pathophysiology of heart failure. Current Heart Failure Reports. 9: 107-16. PMID 22457230 DOI: 10.1007/S11897-012-0089-5 |
0.454 |
|
| 2012 |
Tekabe Y, Luma J, Li Q, Schmidt AM, Ramasamy R, Johnson LL. Imaging of receptors for advanced glycation end products in experimental myocardial ischemia and reperfusion injury. Jacc. Cardiovascular Imaging. 5: 59-67. PMID 22239894 DOI: 10.1016/J.Jcmg.2011.09.016 |
0.401 |
|
| 2012 |
Zeng S, Zhang QY, Huang J, Vedantham S, Rosario R, Ananthakrishnan R, Yan SF, Ramasamy R, DeMatteo RP, Emond JC, Friedman RA, Schmidt AM. Opposing roles of RAGE and Myd88 signaling in extensive liver resection. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 882-93. PMID 22075646 DOI: 10.1096/Fj.11-192997 |
0.325 |
|
| 2012 |
Ramasamy R, Yan SF, Schmidt AM. Advanced glycation endproducts: from precursors to RAGE: round and round we go. Amino Acids. 42: 1151-61. PMID 20957395 DOI: 10.1007/S00726-010-0773-2 |
0.399 |
|
| 2011 |
Ramasamy R, Yan SF, Schmidt AM. Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. Annals of the New York Academy of Sciences. 1243: 88-102. PMID 22211895 DOI: 10.1111/J.1749-6632.2011.06320.X |
0.407 |
|
| 2011 |
Vedantham S, Noh H, Ananthakrishnan R, Son N, Hallam K, Hu Y, Yu S, Shen X, Rosario R, Lu Y, Ravindranath T, Drosatos K, Huggins LA, Schmidt AM, Goldberg IJ, ... Ramasamy R, et al. Human aldose reductase expression accelerates atherosclerosis in diabetic apolipoprotein E-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1805-13. PMID 21636809 DOI: 10.1161/Atvbaha.111.226902 |
0.372 |
|
| 2011 |
Ananthakrishnan R, Li Q, Gomes T, Schmidt AM, Ramasamy R. Aldose reductase pathway contributes to vulnerability of aging myocardium to ischemic injury. Experimental Gerontology. 46: 762-7. PMID 21600277 DOI: 10.1016/J.Exger.2011.05.001 |
0.466 |
|
| 2010 |
Ramasamy R, Yan SF, Schmidt AM. Polyol pathway and RAGE: a central metabolic and signaling axis in diabetic complications. Expert Review of Endocrinology & Metabolism. 5: 65-75. PMID 30934384 DOI: 10.1586/Eem.09.52 |
0.41 |
|
| 2010 |
Hallam KM, Li Q, Ananthakrishnan R, Kalea A, Zou YS, Vedantham S, Schmidt AM, Yan SF, Ramasamy R. Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats. Aging Cell. 9: 776-84. PMID 20670350 DOI: 10.1111/J.1474-9726.2010.00606.X |
0.324 |
|
| 2010 |
Reiniger N, Lau K, McCalla D, Eby B, Cheng B, Lu Y, Qu W, Quadri N, Ananthakrishnan R, Furmansky M, Rosario R, Song F, Rai V, Weinberg A, Friedman R, ... Ramasamy R, et al. Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes. 59: 2043-54. PMID 20627935 DOI: 10.2337/Db09-1766 |
0.359 |
|
| 2010 |
Ramasamy R, Goldberg IJ. Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model. Circulation Research. 106: 1449-58. PMID 20466987 DOI: 10.1161/Circresaha.109.213447 |
0.406 |
|
| 2010 |
Shang L, Ananthakrishnan R, Li Q, Quadri N, Abdillahi M, Zhu Z, Qu W, Rosario R, Touré F, Yan SF, Schmidt AM, Ramasamy R. RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways. Plos One. 5: e10092. PMID 20404919 DOI: 10.1371/Journal.Pone.0010092 |
0.744 |
|
| 2010 |
Yan SF, Ramasamy R, Schmidt AM. The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. Circulation Research. 106: 842-53. PMID 20299674 DOI: 10.1161/Circresaha.109.212217 |
0.429 |
|
| 2010 |
Yan SF, Ramasamy R, Schmidt AM. Soluble RAGE: therapy and biomarker in unraveling the RAGE axis in chronic disease and aging. Biochemical Pharmacology. 79: 1379-86. PMID 20096667 DOI: 10.1016/J.Bcp.2010.01.013 |
0.37 |
|
| 2010 |
D'Agati V, Yan SF, Ramasamy R, Schmidt AM. RAGE, glomerulosclerosis and proteinuria: roles in podocytes and endothelial cells. Trends in Endocrinology and Metabolism: Tem. 21: 50-6. PMID 19783154 DOI: 10.1016/J.Tem.2009.07.003 |
0.33 |
|
| 2009 |
Bucciarelli LG, Pollreisz A, Kebschull M, Ganda A, Kalea AZ, Hudson BI, Zou YS, Lalla E, Ramasamy R, Colombo PC, Schmidt AM, Yan SF. Inflammatory stress in primary venous and aortic endothelial cells of type 1 diabetic mice. Diabetes & Vascular Disease Research. 6: 249-61. PMID 20368219 DOI: 10.1177/1479164109338775 |
0.372 |
|
| 2009 |
Ravindranath TM, Mong PY, Ananthakrishnan R, Li Q, Quadri N, Schmidt AM, Ramasamy R, Wang Q. Novel role for aldose reductase in mediating acute inflammatory responses in the lung. Journal of Immunology (Baltimore, Md. : 1950). 183: 8128-37. PMID 20007578 DOI: 10.4049/Jimmunol.0900720 |
0.32 |
|
| 2009 |
Ramasamy R, Yan SF, Schmidt AM. RAGE: therapeutic target and biomarker of the inflammatory response--the evidence mounts. Journal of Leukocyte Biology. 86: 505-12. PMID 19477910 DOI: 10.1189/Jlb.0409230 |
0.352 |
|
| 2009 |
Yan SF, Yan SD, Ramasamy R, Schmidt AM. Tempering the wrath of RAGE: an emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation. Annals of Medicine. 41: 408-22. PMID 19322705 DOI: 10.1080/07853890902806576 |
0.375 |
|
| 2009 |
Yan SF, Ramasamy R, Schmidt AM. The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease. Expert Reviews in Molecular Medicine. 11: e9. PMID 19278572 DOI: 10.1017/S146239940900101X |
0.432 |
|
| 2009 |
Yan SF, Ramasamy R, Schmidt AM. Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response. Journal of Molecular Medicine (Berlin, Germany). 87: 235-47. PMID 19189073 DOI: 10.1007/S00109-009-0439-2 |
0.423 |
|
| 2009 |
Ananthakrishnan R, Kaneko M, Hwang YC, Quadri N, Gomez T, Li Q, Caspersen C, Ramasamy R. Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore. American Journal of Physiology. Heart and Circulatory Physiology. 296: H333-41. PMID 19060123 DOI: 10.1152/Ajpheart.01012.2008 |
0.433 |
|
| 2008 |
Sternberg DI, Gowda R, Mehra D, Qu W, Weinberg A, Twaddell W, Sarkar J, Wallace A, Hudson B, D'Ovidio F, Arcasoy S, Ramasamy R, D'Armiento J, Schmidt AM, Sonett JR. Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice. The Journal of Thoracic and Cardiovascular Surgery. 136: 1576-85. PMID 19114209 DOI: 10.1016/J.Jtcvs.2008.05.032 |
0.41 |
|
| 2008 |
Li Q, Hwang YC, Ananthakrishnan R, Oates PJ, Guberski D, Ramasamy R. Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts. Cardiovascular Diabetology. 7: 33. PMID 18957123 DOI: 10.1186/1475-2840-7-33 |
0.484 |
|
| 2008 |
Ramasamy R, Yan SF, Schmidt AM. Stopping the primal RAGE reaction in myocardial infarction: capturing adaptive responses to heal the heart? Circulation. 117: 3165-7. PMID 18574057 DOI: 10.1161/Circulationaha.108.784397 |
0.468 |
|
| 2008 |
Ramasamy R, Yan SF, Herold K, Clynes R, Schmidt AM. Receptor for advanced glycation end products: fundamental roles in the inflammatory response: winding the way to the pathogenesis of endothelial dysfunction and atherosclerosis. Annals of the New York Academy of Sciences. 1126: 7-13. PMID 18448789 DOI: 10.1196/Annals.1433.056 |
0.383 |
|
| 2008 |
Bucciarelli LG, Ananthakrishnan R, Hwang YC, Kaneko M, Song F, Sell DR, Strauch C, Monnier VM, Yan SF, Schmidt AM, Ramasamy R. RAGE and modulation of ischemic injury in the diabetic myocardium. Diabetes. 57: 1941-51. PMID 18420491 DOI: 10.2337/Db07-0326 |
0.477 |
|
| 2008 |
Yan SF, Ramasamy R, Schmidt AM. Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications. Nature Clinical Practice. Endocrinology & Metabolism. 4: 285-93. PMID 18332897 DOI: 10.1038/Ncpendmet0786 |
0.414 |
|
| 2008 |
Guo J, Ananthakrishnan R, Qu W, Lu Y, Reiniger N, Zeng S, Ma W, Rosario R, Yan SF, Ramasamy R, D'Agati V, Schmidt AM. RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis. Journal of the American Society of Nephrology : Jasn. 19: 961-72. PMID 18256352 DOI: 10.1681/Asn.2007101109 |
0.444 |
|
| 2008 |
Aleshin A, Ananthakrishnan R, Li Q, Rosario R, Lu Y, Qu W, Song F, Bakr S, Szabolcs M, D'Agati V, Liu R, Homma S, Schmidt AM, Yan SF, Ramasamy R. RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1823-32. PMID 18245563 DOI: 10.1152/Ajpheart.01210.2007 |
0.488 |
|
| 2008 |
Kong L, Andrassy M, Chang JS, Huang C, Asai T, Szabolcs MJ, Homma S, Liu R, Zou YS, Leitges M, Yan SD, Ramasamy R, Schmidt AM, Yan SF. PKCbeta modulates ischemia-reperfusion injury in the heart. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1862-70. PMID 18245560 DOI: 10.1152/Ajpheart.01346.2007 |
0.412 |
|
| 2008 |
Harja E, Bu DX, Hudson BI, Jong SC, Shen X, Hallam K, Kalea AZ, Lu Y, Rosario RH, Oruganti S, Nikolla Z, Belov D, Lalla E, Ramasamy R, Shi FY, et al. Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice Journal of Clinical Investigation. 118: 183-194. PMID 18079965 DOI: 10.1172/Jci32703 |
0.34 |
|
| 2007 |
Clynes R, Moser B, Yan SF, Ramasamy R, Herold K, Schmidt AM. Receptor for AGE (RAGE): Weaving tangled webs within the inflammatory response Current Molecular Medicine. 7: 743-751. PMID 18331232 DOI: 10.2174/156652407783220714 |
0.37 |
|
| 2007 |
Yan SF, D'Agati V, Schmidt AM, Ramasamy R. Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging. Current Molecular Medicine. 7: 699-710. PMID 18331228 DOI: 10.2174/156652407783220732 |
0.461 |
|
| 2007 |
Ramasamy R, Yan SF, Schmidt AM. Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts. Molecular Nutrition & Food Research. 51: 1111-5. PMID 17854009 DOI: 10.1002/Mnfr.200700008 |
0.312 |
|
| 2007 |
Herold K, Moser B, Chen Y, Zeng S, Shi FY, Ramasamy R, Emond J, Clynes R, Schmidt AM. Receptor for advanced glycation end products (RAGE) in a dash to the rescue: Inflammatory signals gone awry in the primal response to stress Journal of Leukocyte Biology. 82: 204-212. PMID 17513693 DOI: 10.1189/Jlb.1206751 |
0.357 |
|
| 2007 |
Yan SF, Barile GR, D'Agati V, Du Yan S, Ramasamy R, Schmidt AM. The biology of RAGE and its ligands: uncovering mechanisms at the heart of diabetes and its complications. Current Diabetes Reports. 7: 146-53. PMID 17425919 DOI: 10.1007/S11892-007-0024-4 |
0.417 |
|
| 2007 |
Ramasamy R, Yan SF, Schmidt AM. The RAGE connection to diabetes and atherosclerosis: an intertwined web of advanced glycation and inflammation Future Lipidology. 2: 239-250. DOI: 10.2217/17460875.2.2.239 |
0.414 |
|
| 2006 |
Ramasamy R, Yan SF, Schmidt AM. Sphingosine-1-phosphate: waging a battle in the diabetic blood vessel. Circulation Research. 99: 669-71. PMID 17008596 DOI: 10.1161/01.Res.0000245453.09893.7F |
0.418 |
|
| 2006 |
Ekong U, Zeng S, Dun H, Feirt N, Guo J, Ippagunta N, Guarrera JV, Lu Y, Weinberg A, Qu W, Ramasamy R, Schmidt AM, Emond JC. Blockade of the receptor for advanced glycation end products attenuates acetaminophen-induced hepatotoxicity in mice. Journal of Gastroenterology and Hepatology. 21: 682-8. PMID 16677153 DOI: 10.1111/J.1440-1746.2006.04225.X |
0.372 |
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| 2006 |
Yan SF, Naka Y, Hudson BI, Herold K, Yan SD, Ramasamy R, Schmidt AM. The ligand/RAGE axis: Lighting the fuse and igniting vascular stress Current Atherosclerosis Reports. 8: 232-239. PMID 16640960 DOI: 10.1007/S11883-006-0078-9 |
0.423 |
|
| 2006 |
Bucciarelli LG, Kaneko M, Ananthakrishnan R, Harja E, Lee LK, Hwang YC, Lerner S, Bakr S, Li Q, Lu Y, Song F, Qu W, Gomez T, Zou YS, Yan SF, ... ... Ramasamy R, et al. Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury. Circulation. 113: 1226-34. PMID 16505177 DOI: 10.1161/Circulationaha.105.575993 |
0.439 |
|
| 2006 |
Ramasamy R, Yan SF, Schmidt AM. Methylglyoxal comes of AGE. Cell. 124: 258-60. PMID 16439200 DOI: 10.1016/J.Cell.2006.01.002 |
0.31 |
|
| 2006 |
Ramasamy R, Yan SF, Schmidt AM. Glycation and RAGE: Common Links in the Pathogenesis of Microvascular and Macrovascular Complications of Diabetes Canadian Journal of Diabetes. 30: 422-429. DOI: 10.1016/S1499-2671(06)04007-X |
0.408 |
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| 2005 |
Ananthakrishnan R, Hallam K, Li Q, Ramasamy R. JAK-STAT pathway in cardiac ischemic stress. Vascular Pharmacology. 43: 353-6. PMID 16260187 DOI: 10.1016/J.Vph.2005.08.020 |
0.407 |
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| 2005 |
Ramasamy R, Yan SF, Schmidt AM. The RAGE axis and endothelial dysfunction: maladaptive roles in the diabetic vasculature and beyond. Trends in Cardiovascular Medicine. 15: 237-43. PMID 16226677 DOI: 10.1016/J.Tcm.2005.08.003 |
0.418 |
|
| 2005 |
Vikramadithyan RK, Hu Y, Noh HL, Liang CP, Hallam K, Tall AR, Ramasamy R, Goldberg IJ. Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice. The Journal of Clinical Investigation. 115: 2434-43. PMID 16127462 DOI: 10.1172/Jci24819 |
0.377 |
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| 2005 |
Kaneko M, Bucciarelli L, Hwang YC, Lee L, Yan SF, Schmidt AM, Ramasamy R. Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury. Annals of the New York Academy of Sciences. 1043: 702-9. PMID 16037296 DOI: 10.1196/Annals.1333.081 |
0.473 |
|
| 2005 |
Kim W, Hudson BI, Moser B, Guo J, Rong LL, Lu Y, Qu W, Lalla E, Lerner S, Chen Y, Yan SS, D'Agati V, Naka Y, Ramasamy R, Herold K, et al. Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis. Annals of the New York Academy of Sciences. 1043: 553-61. PMID 16037278 DOI: 10.1196/Annals.1338.063 |
0.431 |
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| 2005 |
Ramasamy R, Vannucci SJ, Yan SS, Herold K, Yan SF, Schmidt AM. Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation. Glycobiology. 15: 16R-28R. PMID 15764591 DOI: 10.1093/Glycob/Cwi053 |
0.382 |
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| 2005 |
Hwang YC, Shaw S, Kaneko M, Redd H, Marrero MB, Ramasamy R. Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 795-7. PMID 15746188 DOI: 10.1096/Fj.04-2780Fje |
0.441 |
|
| 2005 |
Pillutla P, Hwang YC, Augustus A, Yokoyama M, Yagyu H, Johnston TP, Kaneko M, Ramasamy R, Goldberg IJ. Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy. American Journal of Physiology. Endocrinology and Metabolism. 288: E1229-35. PMID 15701679 DOI: 10.1152/Ajpendo.00273.2004 |
0.32 |
|
| 2004 |
Yan SF, Ramasamy R, Bucciarelli LG, Wendt T, Lee LK, Hudson BI, Stern DM, Lalla E, DU Yan S, Rong LL, Naka Y, Schmidt AM. RAGE and its ligands: a lasting memory in diabetic complications? Diabetes & Vascular Disease Research. 1: 10-20. PMID 16305050 DOI: 10.3132/Dvdr.2004.001 |
0.375 |
|
| 2004 |
Hwang YC, Kaneko M, Bakr S, Liao H, Lu Y, Lewis ER, Yan S, Ii S, Itakura M, Rui L, Skopicki H, Homma S, Schmidt AM, Oates PJ, Szabolcs M, ... Ramasamy R, et al. Central role for aldose reductase pathway in myocardial ischemic injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1192-9. PMID 15284219 DOI: 10.1096/Fj.03-1400Com |
0.466 |
|
| 2004 |
Naka Y, Bucciarelli LG, Wendt T, Lee LK, Rong LL, Ramasamy R, Yan SF, Schmidt AM. RAGE axis: Animal models and novel insights into the vascular complications of diabetes. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1342-9. PMID 15155381 DOI: 10.1161/01.Atv.0000133191.71196.90 |
0.396 |
|
| 2004 |
Ramasamy R, Hwang YC, Liu Y, Son NH, Ma N, Parkinson J, Sciacca R, Albala A, Edwards N, Szabolcs MJ, Cannon PJ. Metabolic and functional protection by selective inhibition of nitric oxide synthase 2 during ischemia-reperfusion in isolated perfused hearts. Circulation. 109: 1668-73. PMID 15051645 DOI: 10.1161/01.Cir.0000124489.46660.2E |
0.402 |
|
| 2004 |
Kaneko M, Ramasamy R. Aldose reductase: a key player in myocardial ischemic injury. Exercise and Sport Sciences Reviews. 32: 19-23. PMID 14748545 DOI: 10.1097/00003677-200401000-00005 |
0.391 |
|
| 2003 |
Yan SF, Ramasamy R, Naka Y, Schmidt AM. Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond. Circulation Research. 93: 1159-69. PMID 14670831 DOI: 10.1161/01.Res.0000103862.26506.3D |
0.434 |
|
| 2003 |
Ramasamy R. Aldose reductase: a novel target for cardioprotective interventions. Current Drug Targets. 4: 625-32. PMID 14577653 DOI: 10.2174/1389450033490768 |
0.393 |
|
| 2003 |
Hudson BI, Bucciarelli LG, Wendt T, Sakaguchi T, Lalla E, Qu W, Lu Y, Lee L, Stern DM, Naka Y, Ramasamy R, Yan SD, Yan SF, D'Agati V, Schmidt AM. Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders. Archives of Biochemistry and Biophysics. 419: 80-8. PMID 14568011 DOI: 10.1016/J.Abb.2003.08.030 |
0.401 |
|
| 2003 |
Hwang YC, Bakr S, Ellery CA, Oates PJ, Ramasamy R. Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2331-3. PMID 14525943 DOI: 10.1096/Fj.03-0128Fje |
0.425 |
|
| 2003 |
Wendt T, Tanji N, Guo J, Hudson BI, Bierhaus A, Ramasamy R, Arnold B, Nawroth PP, Yan SF, D'Agati V, Schmidt AM. Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy. Journal of the American Society of Nephrology : Jasn. 14: 1383-95. PMID 12707408 DOI: 10.1097/01.Asn.0000065100.17349.Ca |
0.437 |
|
| 2002 |
Hwang YC, Sato S, Tsai JY, Yan S, Bakr S, Zhang H, Oates PJ, Ramasamy R. Aldose reductase activation is a key component of myocardial response to ischemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 243-5. PMID 11772943 DOI: 10.1096/Fj.01-0368Fje |
0.437 |
|
| 2002 |
Ramasamy R, Liu H, Cherednichenko G, Schaefer S. Fasting limits the increase in intracellular calcium during ischemia in isolated rat hearts. Basic Research in Cardiology. 96: 463-70. PMID 11605993 DOI: 10.1007/S003950170028 |
0.35 |
|
| 2001 |
Whang J, Ramasamy R, Dizon JM, Bergmann SR. Enalaprilat attenuates ischemic rises in intracellular sodium in the isolated rat heart via the bradykinin receptor. Journal of Cardiovascular Magnetic Resonance. 3: 27-34. PMID 11545137 DOI: 10.1081/Jcmr-100001834 |
0.373 |
|
| 2001 |
Ramasamy R, Hwang Y, Bakr S, Bergmann SR. Protection of ischemic hearts perfused with an anion exchange inhibitor, DIDS, is associated with beneficial changes in substrate metabolism Cardiovascular Research. 51: 275-282. PMID 11470467 DOI: 10.1016/S0008-6363(01)00301-7 |
0.365 |
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| 2001 |
Ramasamy R, Payne JA, Whang J, Bergmann SR, Schaefer S. Protection of ischemic myocardium in diabetics by inhibition of electroneutral Na+-K+-2Cl- cotransporter American Journal of Physiology - Heart and Circulatory Physiology. 281. PMID 11454552 DOI: 10.1152/Ajpheart.2001.281.2.H515 |
0.467 |
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| 2001 |
Ramasamy R, Hwang YC, Whang J, Bergmann SR. Protection of ischemic hearts by high glucose is mediated, in part, by GLUT-4. American Journal of Physiology-Heart and Circulatory Physiology. 281. PMID 11406496 DOI: 10.1152/Ajpheart.2001.281.1.H290 |
0.33 |
|
| 2000 |
Fard A, Tuck CH, Donis JA, Sciacca R, Tullio MRD, Wu HD, Bryant TA, Chen NT, Torres-Tamayo M, Ramasamy R, Berglund L, Ginsberg HN, Homma S, Cannon PJ. Acute Elevations of Plasma Asymmetric Dimethylarginine and Impaired Endothelial Function in Response to a High-Fat Meal in Patients With Type 2 Diabetes Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2039-2044. PMID 10978246 DOI: 10.1161/01.Atv.20.9.2039 |
0.306 |
|
| 2000 |
Salaris SC, Ramasamy R, Bergmann SR. Fructose-2,6-bisphosphate, a potent stimulator of phosphofructokinase, is increased by high exogenous glucose perfusion. Coronary Artery Disease. 11: 279-286. PMID 10832563 DOI: 10.1097/00019501-200005000-00012 |
0.309 |
|
| 1999 |
Lundmark JL, Ramasamy R, Vulliet PR, Schaefer S. Chelerythrine increases Na-K-ATPase activity and limits ischemic injury in isolated rat hearts. The American Journal of Physiology. 277: H999-H1006. PMID 10484422 DOI: 10.1152/Ajpheart.1999.277.3.H999 |
0.318 |
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| 1999 |
Ramasamy R, Liu H, Oates PJ, Schaefer S. Attenuation of ischemia induced increases in sodium and calcium by the aldose reductase inhibitor zopolrestat. Cardiovascular Research. 42: 130-9. PMID 10435004 DOI: 10.1016/S0008-6363(98)00303-4 |
0.416 |
|
| 1999 |
Ramasamy R, Schaefer S. Inhibition of Na+-H+ exchanger protects diabetic and non-diabetic hearts from ischemic injury: Insight into altered susceptibility of diabetic hearts to ischemic injury Journal of Molecular and Cellular Cardiology. 31: 785-797. PMID 10329206 DOI: 10.1006/Jmcc.1998.0908 |
0.447 |
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| 1998 |
Ramasamy R, Trueblood N, Schaefer S. Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 275: H195-H203. PMID 29586607 DOI: 10.1152/Ajpheart.1998.275.1.H195 |
0.414 |
|
| 1998 |
Trueblood N, Ramasamy R. Aldose reductase inhibition improves altered glucose metabolism of isolated diabetic rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 275: H75-H83. PMID 29586592 DOI: 10.1152/Ajpheart.1998.275.1.H75 |
0.404 |
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