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Robert D. Bruno, Ph.D. - Publications

Affiliations: 
2009 Molecular Medicine University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Pharmacology, Molecular Biology, Physiology Biology
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ragle LN, Bruno RD, Boulanger CA, Smith GH. Long-label-retaining mammary epithelial cells are created early in ductal development and distributed throughout the branching ducts. Mechanisms of Development. 103565. PMID 31336167 DOI: 10.1016/J.Mod.2019.103565  0.301
2019 Mollica PA, Creech E, Reid JA, Zamponi M, Sullivan SM, Palmer XL, Sachs PC, Bruno RD. 3D bioprinted mammary organoids and tumoroids in human mammary derived ECM hydrogels. Acta Biomaterialia. PMID 31233891 DOI: 10.1016/J.Actbio.2019.06.017  0.419
2019 Reid JA, Palmer XL, Mollica PA, Northam N, Sachs PC, Bruno RD. A 3D bioprinter platform for mechanistic analysis of tumoroids and chimeric mammary organoids. Scientific Reports. 9: 7466. PMID 31097753 DOI: 10.1038/S41598-019-43922-Z  0.525
2018 Wu V, Auchman M, Mollica PA, Sachs PC, Bruno RD. ALDH1A1 positive cells are a unique component of the tonsillar crypt niche and are lost along with NGFR positive stem cells during tumourigenesis. Pathology. PMID 29891189 DOI: 10.1016/J.Pathol.2018.03.002  0.372
2018 Petrella RA, Mollica PA, Zamponi M, Reid JA, Xiao S, Bruno RD, Sachs PC. 3D bioprinter applied picosecond pulsed electric fields for targeted manipulation of proliferation and lineage specific gene expression in neural stem cells. Journal of Neural Engineering. PMID 29848804 DOI: 10.1088/1741-2552/Aac8Ec  0.319
2018 LaFosse P, Zamponi M, Mollica P, Therrien K, Bruno R, Sachs P, Peixoto N. Effect of substrate coating material on spontaneous activity of human-induced pluripotent stem cell-derived neuronal stem cells Frontiers in Cellular Neuroscience. 12. DOI: 10.3389/Conf.Fncel.2018.38.00115  0.306
2017 Sachs PC, Mollica PA, Bruno RD. Tissue specific microenvironments: a key tool for tissue engineering and regenerative medicine. Journal of Biological Engineering. 11: 34. PMID 29177006 DOI: 10.1186/S13036-017-0077-0  0.311
2017 Bruno RD, Fleming JM, George AL, Boulanger CA, Schedin P, Smith GH. Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo. Scientific Reports. 7: 40196. PMID 28071703 DOI: 10.1038/Srep40196  0.369
2016 Kwegyir-Afful AK, Bruno RD, Purushottamachar P, Murigi FN, Njar VC. Galeterone and VNPT55 disrupts Mnk-eIF4E to inhibit prostate cancer cell migration and invasion. The Febs Journal. PMID 27618366 DOI: 10.1111/Febs.13895  0.744
2016 Reid JA, Mollica PA, Johnson GD, Ogle RC, Bruno RD, Sachs PC. Accessible bioprinting: adaptation of a low-cost 3D-printer for precise cell placement and stem cell differentiation. Biofabrication. 8: 025017. PMID 27271208 DOI: 10.1088/1758-5090/8/2/025017  0.338
2015 Wu VF, Yu T, Harding B, Bruno R. Abstract 1396: Unraveling the cellular hierarchywithin human tonsillar crypt epithelium and oropharyngeal squamous cellcarcinoma tumors Cancer Research. 75: 1396-1396. DOI: 10.1158/1538-7445.Am2015-1396  0.373
2014 Bruno RD, Smith GH. A potential mechanism for extracellular matrix induction of breast cancer cell normality. Breast Cancer Research : Bcr. 16: 302. PMID 25927296 DOI: 10.1186/Bcr3617  0.497
2014 Godbole AM, Ramalingam S, Ramamurthy VP, Khandelwal A, Bruno RD, Upreti VV, Gediya LK, Purushottamachar P, Mbatia HW, Addya S, Ambulos N, Njar VC. VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats. European Journal of Pharmacology. 734: 98-104. PMID 24726842 DOI: 10.1016/J.Ejphar.2014.04.004  0.643
2014 Bruno RD, Boulanger CA, Rosenfield SM, Anderson LH, Lydon JP, Smith GH. Paracrine-rescued lobulogenesis in chimeric outgrowths comprising progesterone-receptor-null mammary epithelium and redirected wild-type testicular cells. Journal of Cell Science. 127: 27-32. PMID 24190884 DOI: 10.1242/Jcs.140749  0.362
2013 Boulanger CA, Bruno RD, Mack DL, Gonzales M, Castro NP, Salomon DS, Smith GH. Embryonic stem cells are redirected to non-tumorigenic epithelial cell fate by interaction with the mammary microenvironment. Plos One. 8: e62019. PMID 23637952 DOI: 10.1371/Journal.Pone.0062019  0.387
2012 Bruno RD, Smith GH. Reprogramming non-mammary and cancer cells in the developing mouse mammary gland. Seminars in Cell & Developmental Biology. 23: 591-8. PMID 22430755 DOI: 10.1016/J.Semcdb.2012.03.007  0.403
2012 Bruno RD, Boulanger CA, Smith GH. Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor. Oncogene. 31: 60-67. PMID 21666720 DOI: 10.1038/Onc.2011.215  0.323
2012 Boulanger CA, Bruno RD, Rosu-Myles M, Smith GH. The mouse mammary microenvironment redirects mesoderm-derived bone marrow cells to a mammary epithelial progenitor cell fate. Stem Cells and Development. 21: 948-54. PMID 21649558 DOI: 10.1089/Scd.2011.0148  0.366
2011 Bruno RD, Smith GH. Role of epithelial stem/progenitor cells in mammary cancer. Gene Expression. 15: 133-40. PMID 22268295 DOI: 10.3727/105221611X13176664479368  0.358
2011 Bruno RD, Vasaitis TS, Gediya LK, Purushottamachar P, Godbole AM, Ates-Alagoz Z, Brodie AM, Njar VC. Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model. Steroids. 76: 1268-79. PMID 21729712 DOI: 10.1016/J.Steroids.2011.06.002  0.741
2011 Vasaitis TS, Bruno RD, Njar VC. CYP17 inhibitors for prostate cancer therapy. The Journal of Steroid Biochemistry and Molecular Biology. 125: 23-31. PMID 21092758 DOI: 10.1016/J.Jsbmb.2010.11.005  0.722
2011 Bruno RD, Smith GH. Functional characterization of stem cell activity in the mouse mammary gland. Stem Cell Reviews. 7: 238-47. PMID 20853073 DOI: 10.1007/S12015-010-9191-9  0.325
2010 Bussard KM, Boulanger CA, Booth BW, Bruno RD, Smith GH. Reprogramming human cancer cells in the mouse mammary gland. Cancer Research. 70: 6336-43. PMID 20647316 DOI: 10.1158/0008-5472.Can-10-0591  0.443
2008 Bruno RD, Gover TD, Burger AM, Brodie AM, Njar VC. 17alpha-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response. Molecular Cancer Therapeutics. 7: 2828-36. PMID 18790763 DOI: 10.1158/1535-7163.Mct-08-0336  0.72
2008 Purushottamachar P, Khandelwal A, Vasaitis TS, Bruno RD, Gediya LK, Njar VC. Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agent. Bioorganic & Medicinal Chemistry. 16: 3519-29. PMID 18316193 DOI: 10.1016/J.Bmc.2008.02.031  0.755
2007 Bruno RD, Njar VC. Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development. Bioorganic & Medicinal Chemistry. 15: 5047-60. PMID 17544277 DOI: 10.1016/J.Bmc.2007.05.046  0.706
2007 Purushottamachar P, Khandelwal A, Chopra P, Maheshwari N, Gediya LK, Vasaitis TS, Bruno RD, Clement OO, Njar VC. First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents. Bioorganic & Medicinal Chemistry. 15: 3413-21. PMID 17383188 DOI: 10.1016/J.Bmc.2007.03.019  0.747
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