| Year |
Citation |
Score |
| 2023 |
Butler JH, Painter HJ, Bremers EK, Krai P, Llinás M, Cassera MB. Cripowellins Pause Intraerythrocytic Development at the Ring Stage. Molecules (Basel, Switzerland). 28. PMID 36985570 DOI: 10.3390/molecules28062600 |
0.742 |
|
| 2022 |
Russell TJ, De Silva EK, Crowley V, Shaw-Saliba K, Dube N, Josling G, Pasaje CFA, Kouskoumvekaki I, Panagiotou G, Niles JC, Jacobs-Lorena M, Denise Okafor C, Gamo FJ, Llinás M. Inhibitors of ApiAP2 protein DNA binding exhibit multistage activity against Plasmodium parasites. Plos Pathogens. 18: e1010887. PMID 36223427 DOI: 10.1371/journal.ppat.1010887 |
0.809 |
|
| 2022 |
Painter HJ, Chung NC, Sebastian A, Albert I, Storey JD, Llinás M. Author Correction: Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development. Nature Communications. 13: 1497. PMID 35292664 DOI: 10.1038/s41467-022-29067-0 |
0.722 |
|
| 2022 |
Campelo Morillo RA, Tong X, Xie W, Abel S, Orchard LM, Daher W, Patel DJ, Llinás M, Le Roch KG, Kafsack BFC. The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites. Nature Microbiology. PMID 35087229 DOI: 10.1038/s41564-021-01045-0 |
0.403 |
|
| 2021 |
Reader J, van der Watt ME, Taylor D, Le Manach C, Mittal N, Ottilie S, Theron A, Moyo P, Erlank E, Nardini L, Venter N, Lauterbach S, Bezuidenhout B, Horatscheck A, van Heerden A, et al. Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box. Nature Communications. 12: 269. PMID 33431834 DOI: 10.1038/s41467-020-20629-8 |
0.308 |
|
| 2020 |
Singh S, Santos JM, Orchard LM, Yamada N, van Biljon R, Painter HJ, Mahony S, Llinás M. The PfAP2-G2 transcription factor is a critical regulator of gametocyte maturation. Molecular Microbiology. PMID 33368818 DOI: 10.1111/mmi.14676 |
0.789 |
|
| 2020 |
Painter HJ, Morrisey JM, Mather MW, Orchard LM, Luck C, Smilkstein MJ, Riscoe MK, Vaidya AB, Llinás M. Atypical molecular basis for drug resistance to mitochondrial function inhibitors in . Antimicrobial Agents and Chemotherapy. PMID 33361312 DOI: 10.1128/AAC.02143-20 |
0.769 |
|
| 2020 |
Andrade CM, Fleckenstein H, Thomson-Luque R, Doumbo S, Lima NF, Anderson C, Hibbert J, Hopp CS, Tran TM, Li S, Niangaly M, Cisse H, Doumtabe D, Skinner J, Sturdevant D, et al. Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season. Nature Medicine. PMID 33106664 DOI: 10.1038/s41591-020-1084-0 |
0.323 |
|
| 2020 |
Shafik SH, Cobbold SA, Barkat K, Richards SN, Lancaster NS, Llinás M, Hogg SJ, Summers RL, McConville MJ, Martin RE. The natural function of the malaria parasite's chloroquine resistance transporter. Nature Communications. 11: 3922. PMID 32764664 DOI: 10.1038/S41467-020-17781-6 |
0.743 |
|
| 2020 |
Chappell L, Ross P, Orchard L, Russell TJ, Otto TD, Berriman M, Rayner JC, Llinás M. Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq. Bmc Genomics. 21: 395. PMID 32513207 DOI: 10.1186/S12864-020-06787-5 |
0.432 |
|
| 2020 |
Vanaerschot M, Murithi JM, Pasaje CFA, Ghidelli-Disse S, Dwomoh L, Bird M, Spottiswoode N, Mittal N, Arendse LB, Owen ES, Wicht KJ, Siciliano G, Bösche M, Yeo T, Kumar TRS, et al. Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity. Cell Chemical Biology. PMID 32359426 DOI: 10.1016/J.Chembiol.2020.04.001 |
0.387 |
|
| 2020 |
Ling L, Mulaka M, Munro J, Dass S, Mather MW, Riscoe MK, Llinás M, Zhou J, Ke H. Genetic ablation of the mitoribosome in the malaria parasite sensitizes it to antimalarials that target mitochondrial functions. The Journal of Biological Chemistry. PMID 32273345 DOI: 10.1074/Jbc.Ra120.012646 |
0.374 |
|
| 2020 |
Josling GA, Russell TJ, Venezia J, Orchard L, van Biljon R, Painter HJ, Llinás M. Dissecting the role of PfAP2-G in malaria gametocytogenesis. Nature Communications. 11: 1503. PMID 32198457 DOI: 10.1038/S41467-020-15026-0 |
0.755 |
|
| 2020 |
Akkaya M, Bansal A, Sheehan PW, Pena M, Molina-Cruz A, Orchard LM, Cimperman CK, Qi CF, Ross P, Yazew T, Sturdevant D, Anzick SL, Thiruvengadam G, Otto TD, Billker O, et al. A single-nucleotide polymorphism in a ApiAP2 transcription factor alters the development of host immunity. Science Advances. 6: eaaw6957. PMID 32076635 DOI: 10.1126/Sciadv.Aaw6957 |
0.396 |
|
| 2019 |
Murithi JM, Owen ES, Istvan ES, Lee MCS, Ottilie S, Chibale K, Goldberg DE, Winzeler EA, Llinás M, Fidock DA, Vanaerschot M. Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery. Cell Chemical Biology. PMID 31813848 DOI: 10.1016/J.Chembiol.2019.11.009 |
0.406 |
|
| 2019 |
van Biljon R, van Wyk R, Painter HJ, Orchard L, Reader J, Niemand J, Llinás M, Birkholtz LM. Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation. Bmc Genomics. 20: 920. PMID 31795940 DOI: 10.1186/S12864-019-6322-9 |
0.774 |
|
| 2019 |
Clements RL, Streva V, Dumoulin P, Huang W, Owens E, Raj DK, Burleigh B, Llinás M, Winzeler EA, Zhang Q, Dvorin JD. A novel antiparasitic compound kills ring-stage Plasmodium falciparum and retains activity against artemisinin-resistant parasites. The Journal of Infectious Diseases. PMID 31616928 DOI: 10.1093/Infdis/Jiz534 |
0.415 |
|
| 2019 |
Ngwa CJ, Kiesow MJ, Orchard LM, Farrukh A, Llinás M, Pradel G. The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Gametocyte Development and Transmission. International Journal of Molecular Sciences. 20. PMID 31615031 DOI: 10.3390/Ijms20205087 |
0.389 |
|
| 2019 |
Schalkwijk J, Allman EL, Jansen PAM, de Vries LE, Verhoef JMJ, Jackowski S, Botman PNM, Beuckens-Schortinghuis CA, Koolen KMJ, Bolscher JM, Vos MW, Miller K, Reeves SA, Pett H, Trevitt G, et al. Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in . Science Translational Medicine. 11. PMID 31534021 DOI: 10.1126/Scitranslmed.Aas9917 |
0.47 |
|
| 2019 |
Lee MCS, Lindner SE, Lopez-Rubio JJ, Llinás M. Cutting back malaria: CRISPR/Cas9 genome editing of Plasmodium. Briefings in Functional Genomics. PMID 31365053 DOI: 10.1093/Bfgp/Elz012 |
0.411 |
|
| 2019 |
Josling GA, Llinás M. Commitment Isn't for Everyone. Trends in Parasitology. PMID 31053335 DOI: 10.1016/J.Pt.2019.03.012 |
0.366 |
|
| 2019 |
Istvan E, Das S, Bhatnagar S, Beck JR, Owen E, Llinas M, Ganesan SM, Niles JC, Winzeler E, Vaidya AB, Goldberg DE. Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis. Elife. 8. PMID 30888318 DOI: 10.7554/Elife.40529 |
0.6 |
|
| 2019 |
Istvan ES, Das S, Bhatnagar S, Beck JR, Owen E, Llinas M, Ganesan SM, Niles JC, Winzeler E, Vaidya AB, Goldberg DE. Author response: Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis Elife. DOI: 10.7554/Elife.40529.032 |
0.573 |
|
| 2018 |
Leopold SJ, Ghose A, Allman EL, Kingston HWF, Hossain A, Dutta AK, Plewes K, Chotivanich K, Day NPJ, Tarning J, Winterberg M, White NJ, Llinás M, Dondorp AM. Identifying the components of acidosis in patients with severe P. falciparum malaria using metabolomics. The Journal of Infectious Diseases. PMID 30566600 DOI: 10.1093/Infdis/Jiy727 |
0.387 |
|
| 2018 |
Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado Rodriguez JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, et al. Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science (New York, N.Y.). 362. PMID 30523084 DOI: 10.1126/Science.Aat9446 |
0.391 |
|
| 2018 |
van Biljon R, Niemand J, van Wyk R, Clark K, Verlinden B, Abrie C, von Grüning H, Smidt W, Smit A, Reader J, Painter H, Llinás M, Doerig C, Birkholtz LM. Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites. Scientific Reports. 8: 16581. PMID 30409996 DOI: 10.1038/S41598-018-34964-W |
0.774 |
|
| 2018 |
Lee AH, Dhingra SK, Lewis IA, Singh MK, Siriwardana A, Dalal S, Rubiano K, Klein MS, Baska KS, Krishna S, Klemba M, Roepe PD, Llinás M, Garcia CRS, Fidock DA. Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter. Scientific Reports. 8: 13578. PMID 30206341 DOI: 10.1038/S41598-018-31715-9 |
0.664 |
|
| 2018 |
Shukla A, Olszewski KL, Llinás M, Rommereim LM, Fox BA, Bzik DJ, Xia D, Wastling J, Beiting D, Roos DS, Shanmugam D. Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii. International Journal For Parasitology. PMID 30176233 DOI: 10.1016/J.Ijpara.2018.05.013 |
0.743 |
|
| 2018 |
Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, et al. A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum. Plos Pathogens. 14: e1007249. PMID 30133543 DOI: 10.1371/Journal.Ppat.1007249 |
0.459 |
|
| 2018 |
Painter HJ, Chung NC, Sebastian A, Albert I, Storey JD, Llinás M. Genome-wide real-time in vivo transcriptional dynamics during Plasmodium falciparum blood-stage development. Nature Communications. 9: 2656. PMID 29985403 DOI: 10.1038/S41467-018-04966-3 |
0.759 |
|
| 2018 |
Josling GA, Williamson KC, Llinás M. Regulation of Sexual Commitment and Gametocytogenesis in Malaria Parasites. Annual Review of Microbiology. PMID 29975590 DOI: 10.1146/Annurev-Micro-090817-062712 |
0.406 |
|
| 2018 |
Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, et al. Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics. Science (New York, N.Y.). 359: 191-199. PMID 29326268 DOI: 10.1126/Science.Aan4472 |
0.764 |
|
| 2017 |
Gisselberg JE, Herrera Z, Orchard LM, Llinás M, Yeh E. Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site. Cell Chemical Biology. PMID 29276048 DOI: 10.1016/J.Chembiol.2017.11.010 |
0.386 |
|
| 2017 |
Llinás M. Less Lipid, More Commitment. Cell. 171: 1474-1476. PMID 29245007 DOI: 10.1016/J.Cell.2017.11.044 |
0.346 |
|
| 2017 |
Turnbull LB, Siwo GH, Button-Simons KA, Tan A, Checkley LA, Painter HJ, Llinás M, Ferdig MT. Simultaneous genome-wide gene expression and transcript isoform profiling in the human malaria parasite. Plos One. 12: e0187595. PMID 29112986 DOI: 10.1371/Journal.Pone.0187595 |
0.746 |
|
| 2017 |
Ngwa CJ, Kiesow MJ, Papst O, Orchard LM, Filarsky M, Rosinski AN, Voss TS, Llinás M, Pradel G. Transcriptional Profiling Defines Histone Acetylation as a Regulator of Gene Expression during Human-to-Mosquito Transmission of the Malaria Parasite Plasmodium falciparum. Frontiers in Cellular and Infection Microbiology. 7: 320. PMID 28791254 DOI: 10.3389/Fcimb.2017.00320 |
0.454 |
|
| 2017 |
Mancio-Silva L, Slavic K, Grilo Ruivo MT, Grosso AR, Modrzynska KK, Vera IM, Sales-Dias J, Gomes AR, MacPherson CR, Crozet P, Adamo M, Baena-Gonzalez E, Tewari R, Llinás M, Billker O, et al. Nutrient sensing modulates malaria parasite virulence. Nature. PMID 28678779 DOI: 10.1038/Nature23009 |
0.479 |
|
| 2017 |
Santos JM, Josling G, Ross P, Joshi P, Orchard L, Campbell T, Schieler A, Cristea IM, Llinás M. Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor. Cell Host & Microbe. 21: 731-741.e10. PMID 28618269 DOI: 10.1016/J.Chom.2017.05.006 |
0.665 |
|
| 2017 |
Painter HJ, Carrasquilla M, Llinás M. Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum. Genome Research. PMID 28416533 DOI: 10.1101/Gr.217356.116 |
0.775 |
|
| 2017 |
Coetzee N, Sidoli S, van Biljon R, Painter H, Llinás M, Garcia BA, Birkholtz LM. Quantitative chromatin proteomics reveals a dynamic histone post-translational modification landscape that defines asexual and sexual Plasmodium falciparum parasites. Scientific Reports. 7: 607. PMID 28377601 DOI: 10.1038/S41598-017-00687-7 |
0.758 |
|
| 2016 |
Gabryszewski SJ, Dhingra SK, Combrinck JM, Lewis IA, Callaghan PS, Hassett MR, Siriwardana A, Henrich PP, Lee AH, Gnädig NF, Musset L, Llinás M, Egan TJ, Roepe PD, Fidock DA. Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology. Plos Pathogens. 12: e1005976. PMID 27832198 DOI: 10.1371/Journal.Ppat.1005976 |
0.634 |
|
| 2016 |
Allman EL, Painter HJ, Samra J, Carrasquilla M, Llinás M. Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways. Antimicrobial Agents and Chemotherapy. PMID 27572391 DOI: 10.1128/Aac.01224-16 |
0.774 |
|
| 2016 |
Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, et al. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. Plos Pathogens. 12: e1005763. PMID 27467575 DOI: 10.1371/Journal.Ppat.1005763 |
0.573 |
|
| 2016 |
Shears MJ, MacRae JI, Mollard V, Goodman CD, Sturm A, Orchard LM, Llinás M, McConville MJ, Botté CY, McFadden GI. Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast. Cellular Microbiology. PMID 27324409 DOI: 10.1111/Cmi.12633 |
0.435 |
|
| 2016 |
Cobbold SA, Santos JM, Ochoa A, Perlman DH, Llinás M. Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite. Scientific Reports. 6: 19722. PMID 26813983 DOI: 10.1038/Srep19722 |
0.826 |
|
| 2015 |
Adjalley SH, Scanfeld D, Kozlowski E, Llinás M, Fidock DA. Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1. Bmc Genomics. 16: 1090. PMID 26689807 DOI: 10.1186/S12864-015-2320-8 |
0.452 |
|
| 2015 |
Cobbold SA, Llinás M, Kirk K. Sequestration and metabolism of host cell arginine by the intraerythrocytic malaria parasite Plasmodium falciparum. Cellular Microbiology. PMID 26633083 DOI: 10.1111/Cmi.12552 |
0.763 |
|
| 2015 |
Ochoa A, Storey JD, Llinás M, Singh M. Beyond the E-Value: Stratified Statistics for Protein Domain Prediction. Plos Computational Biology. 11: e1004509. PMID 26575353 DOI: 10.1371/Journal.Pcbi.1004509 |
0.574 |
|
| 2015 |
Pulcini S, Staines HM, Lee AH, Shafik SH, Bouyer G, Moore CM, Daley DA, Hoke MJ, Altenhofen LM, Painter HJ, Mu J, Ferguson DJ, Llinás M, Martin RE, Fidock DA, et al. Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities. Scientific Reports. 5: 14552. PMID 26420308 DOI: 10.1038/Srep14552 |
0.749 |
|
| 2015 |
Josling GA, Llinás M. Sexual development in Plasmodium parasites: knowing when it's time to commit. Nature Reviews. Microbiology. 13: 573-87. PMID 26272409 DOI: 10.1038/Nrmicro3519 |
0.433 |
|
| 2015 |
Ke H, Lewis IA, Morrisey JM, McLean KJ, Ganesan SM, Painter HJ, Mather MW, Jacobs-Lorena M, Llinás M, Vaidya AB. Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle. Cell Reports. 11: 164-74. PMID 25843709 DOI: 10.1016/J.Celrep.2015.03.011 |
0.812 |
|
| 2015 |
Eshar S, Altenhofen L, Rabner A, Ross P, Fastman Y, Mandel-Gutfreund Y, Karni R, Llinás M, Dzikowski R. PfSR1 controls alternative splicing and steady-state RNA levels in Plasmodium falciparum through preferential recognition of specific RNA motifs. Molecular Microbiology. 96: 1283-97. PMID 25807998 DOI: 10.1111/Mmi.13007 |
0.343 |
|
| 2014 |
Lisewski AM, Quiros JP, Ng CL, Adikesavan AK, Miura K, Putluri N, Eastman RT, Scanfeld D, Regenbogen SJ, Altenhofen L, Llinás M, Sreekumar A, Long C, Fidock DA, Lichtarge O. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 158: 916-28. PMID 25126794 DOI: 10.1016/J.Cell.2014.07.011 |
0.341 |
|
| 2014 |
Coleman BI, Skillman KM, Jiang RH, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BF, Marti M, Llinás M, Buckee CO, Duraisingh MT. A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion. Cell Host & Microbe. 16: 177-86. PMID 25121747 DOI: 10.1016/J.Chom.2014.06.014 |
0.785 |
|
| 2014 |
Oberstaller J, Pumpalova Y, Schieler A, Llinás M, Kissinger JC. The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems. Nucleic Acids Research. 42: 8271-84. PMID 24957599 DOI: 10.1093/Nar/Gku500 |
0.384 |
|
| 2014 |
O'Hara JK, Kerwin LJ, Cobbold SA, Tai J, Bedell TA, Reider PJ, Llinás M. Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum. Plos One. 9: e94061. PMID 24747974 DOI: 10.1371/Journal.Pone.0094061 |
0.805 |
|
| 2014 |
Kafsack BF, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA, Cortés A, Llinás M. A transcriptional switch underlies commitment to sexual development in malaria parasites. Nature. 507: 248-52. PMID 24572369 DOI: 10.1038/Nature12920 |
0.798 |
|
| 2014 |
Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BF, Williams AE, Llinás M, Berriman M, Billker O, et al. A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium. Nature. 507: 253-7. PMID 24572359 DOI: 10.1038/Nature12970 |
0.789 |
|
| 2014 |
Lewis IA, Wacker M, Olszewski KL, Cobbold SA, Baska KS, Tan A, Ferdig MT, Llinás M. Metabolic QTL analysis links chloroquine resistance in Plasmodium falciparum to impaired hemoglobin catabolism. Plos Genetics. 10: e1004085. PMID 24391526 DOI: 10.1371/Journal.Pgen.1004085 |
0.806 |
|
| 2014 |
Klein EY, Graham AL, Llinás M, Levin S. Cross-reactive immune responses as primary drivers of malaria chronicity. Infection and Immunity. 82: 140-51. PMID 24126530 DOI: 10.1128/Iai.00958-13 |
0.363 |
|
| 2013 |
Carter LM, Kafsack BF, Llinás M, Mideo N, Pollitt LC, Reece SE. Stress and sex in malaria parasites: Why does commitment vary? Evolution, Medicine, and Public Health. 2013: 135-47. PMID 24481194 DOI: 10.1093/Emph/Eot011 |
0.784 |
|
| 2013 |
Cobbold SA, Vaughan AM, Lewis IA, Painter HJ, Camargo N, Perlman DH, Fishbaugher M, Healer J, Cowman AF, Kappe SH, Llinás M. Kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in Plasmodium falciparum. The Journal of Biological Chemistry. 288: 36338-50. PMID 24163372 DOI: 10.1074/Jbc.M113.503557 |
0.806 |
|
| 2013 |
Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D, Bauerle C, Bisaria N, Bradley PH, Breunig JS, Bush E, et al. A new system for comparative functional genomics of Saccharomyces yeasts. Genetics. 195: 275-87. PMID 23852385 DOI: 10.1534/Genetics.113.152918 |
0.32 |
|
| 2013 |
Mira-Martínez S, Rovira-Graells N, Crowley VM, Altenhofen LM, Llinás M, Cortés A. Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites. Cellular Microbiology. 15: 1913-23. PMID 23819786 DOI: 10.1111/Cmi.12162 |
0.425 |
|
| 2013 |
Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 497: 652. PMID 23615611 DOI: 10.1038/Nature12164 |
0.738 |
|
| 2013 |
Radke JB, Lucas O, De Silva EK, Ma Y, Sullivan WJ, Weiss LM, Llinas M, White MW. ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst. Proceedings of the National Academy of Sciences of the United States of America. 110: 6871-6. PMID 23572590 DOI: 10.1073/Pnas.1300059110 |
0.798 |
|
| 2013 |
Olszewski KL, Llinás M. Extraction of hydrophilic metabolites from Plasmodium falciparum-infected erythrocytes for metabolomic analysis. Methods in Molecular Biology (Clifton, N.J.). 923: 259-66. PMID 22990783 DOI: 10.1007/978-1-62703-026-7_17 |
0.752 |
|
| 2013 |
Painter HJ, Altenhofen LM, Kafsack BF, Llinás M. Whole-genome analysis of Plasmodium spp. Utilizing a new agilent technologies DNA microarray platform. Methods in Molecular Biology (Clifton, N.J.). 923: 213-9. PMID 22990780 DOI: 10.1007/978-1-62703-026-7_14 |
0.783 |
|
| 2013 |
Olszewski KL, Llinás M. Extraction of hydrophilic metabolites from plasmodium falciparum -infected erythrocytes for metabolomic analysis Methods in Molecular Biology. 923: 259-266. DOI: 10.1007/978-1-62703-26-7_17 |
0.681 |
|
| 2012 |
Pino P, Sebastian S, Kim EA, Bush E, Brochet M, Volkmann K, Kozlowski E, Llinás M, Billker O, Soldati-Favre D. A tetracycline-repressible transactivator system to study essential genes in malaria parasites. Cell Host & Microbe. 12: 824-34. PMID 23245327 DOI: 10.1016/J.Chom.2012.10.016 |
0.702 |
|
| 2012 |
Babbitt SE, Altenhofen L, Cobbold SA, Istvan ES, Fennell C, Doerig C, Llinás M, Goldberg DE. Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state. Proceedings of the National Academy of Sciences of the United States of America. 109: E3278-87. PMID 23112171 DOI: 10.1073/Pnas.1209823109 |
0.749 |
|
| 2012 |
Straimer J, Lee MC, Lee AH, Zeitler B, Williams AE, Pearl JR, Zhang L, Rebar EJ, Gregory PD, Llinás M, Urnov FD, Fidock DA. Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases. Nature Methods. 9: 993-8. PMID 22922501 DOI: 10.1038/Nmeth.2143 |
0.422 |
|
| 2012 |
Kafsack BF, Painter HJ, Llinás M. New Agilent platform DNA microarrays for transcriptome analysis of Plasmodium falciparum and Plasmodium berghei for the malaria research community. Malaria Journal. 11: 187. PMID 22681930 DOI: 10.1186/1475-2875-11-187 |
0.791 |
|
| 2012 |
Painter HJ, Llinás M. Comment on "Emerging functions of transcription factors in malaria parasite". Journal of Biomedicine & Biotechnology. 2012: 754054. PMID 22675258 DOI: 10.1155/2012/754054 |
0.78 |
|
| 2012 |
Klein EY, Lewis IA, Jung C, Llinás M, Levin SA. Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana. Malaria Journal. 11: 110. PMID 22482747 DOI: 10.1186/1475-2875-11-110 |
0.55 |
|
| 2011 |
Lindner SE, Llinás M, Keck JL, Kappe SH. The primase domain of PfPrex is a proteolytically matured, essential enzyme of the apicoplast. Molecular and Biochemical Parasitology. 180: 69-75. PMID 21856338 DOI: 10.1016/J.Molbiopara.2011.08.002 |
0.637 |
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| 2011 |
Storm J, Perner J, Aparicio I, Patzewitz EM, Olszewski K, Llinas M, Engel PC, Müller S. Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development. Malaria Journal. 10: 193. PMID 21756354 DOI: 10.1186/1475-2875-10-193 |
0.757 |
|
| 2011 |
Ochoa A, Llinás M, Singh M. Using context to improve protein domain identification. Bmc Bioinformatics. 12: 90. PMID 21453511 DOI: 10.1186/1471-2105-12-90 |
0.585 |
|
| 2011 |
Amino R, Bassat Q, Baum J, Billker O, Bogyo M, Bousema T, Christophides G, Deitsch K, Dinglasan R, Djimde A, Duraisingh M, Dzinjalamala F, Happi C, Heussler V, Kramarik J, et al. A research agenda for malaria eradication: basic science and enabling technologies Plos Medicine. 8: 1-6. PMID 21311584 DOI: 10.1371/Journal.Pmed.1000399 |
0.405 |
|
| 2011 |
Painter HJ, Campbell TL, Llinás M. The Apicomplexan AP2 family: integral factors regulating Plasmodium development. Molecular and Biochemical Parasitology. 176: 1-7. PMID 21126543 DOI: 10.1016/J.Molbiopara.2010.11.014 |
0.799 |
|
| 2011 |
Olszewski KL, Llinás M. Central carbon metabolism of Plasmodium parasites. Molecular and Biochemical Parasitology. 175: 95-103. PMID 20849882 DOI: 10.1016/J.Molbiopara.2010.09.001 |
0.731 |
|
| 2011 |
Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Erratum: Branched tricarboxylic acid metabolism in Plasmodium falciparum Nature. 469: 432-432. DOI: 10.1038/Nature09712 |
0.756 |
|
| 2010 |
Campbell TL, De Silva EK, Olszewski KL, Elemento O, Llinás M. Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite. Plos Pathogens. 6: e1001165. PMID 21060817 DOI: 10.1371/Journal.Ppat.1001165 |
0.805 |
|
| 2010 |
Helm S, Lehmann C, Nagel A, Stanway RR, Horstmann S, Llinas M, Heussler VT. Identification and characterization of a liver stage-specific promoter region of the malaria parasite Plasmodium. Plos One. 5: e13653. PMID 21048918 DOI: 10.1371/Journal.Pone.0013653 |
0.459 |
|
| 2010 |
Plata G, Hsiao TL, Olszewski KL, Llinás M, Vitkup D. Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network. Molecular Systems Biology. 6: 408. PMID 20823846 DOI: 10.1038/Msb.2010.60 |
0.732 |
|
| 2010 |
Olszewski KL, Mather MW, Morrisey JM, Garcia BA, Vaidya AB, Rabinowitz JD, Llinás M. Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature. 466: 774-8. PMID 20686576 DOI: 10.1038/Nature09301 |
0.785 |
|
| 2010 |
Dowling DP, Ilies M, Olszewski KL, Portugal S, Mota MM, Llinás M, Christianson DW. Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection . Biochemistry. 49: 5600-8. PMID 20527960 DOI: 10.1021/Bi100390Z |
0.72 |
|
| 2010 |
Kafsack BF, Llinás M. Eating at the table of another: metabolomics of host-parasite interactions. Cell Host & Microbe. 7: 90-9. PMID 20159614 DOI: 10.1016/J.Chom.2010.01.008 |
0.789 |
|
| 2010 |
Otto TD, Wilinski D, Assefa S, Keane TM, Sarry LR, Böhme U, Lemieux J, Barrell B, Pain A, Berriman M, Newbold C, Llinás M. New insights into the blood-stage transcriptome of Plasmodium falciparum using RNA-Seq. Molecular Microbiology. 76: 12-24. PMID 20141604 DOI: 10.1111/J.1365-2958.2009.07026.X |
0.409 |
|
| 2010 |
Lindner SE, De Silva EK, Keck JL, Llinás M. Structural determinants of DNA binding by a P. falciparum ApiAP2 transcriptional regulator. Journal of Molecular Biology. 395: 558-67. PMID 19913037 DOI: 10.1016/J.Jmb.2009.11.004 |
0.782 |
|
| 2009 |
Howitt CA, Wilinski D, Llinás M, Templeton TJ, Dzikowski R, Deitsch KW. Clonally variant gene families in Plasmodium falciparum share a common activation factor. Molecular Microbiology. 73: 1171-85. PMID 19708920 DOI: 10.1111/J.1365-2958.2009.06846.X |
0.353 |
|
| 2009 |
Zawada RJ, Kwan P, Olszewski KL, Llinas M, Huang SG. Quantitative determination of urea concentrations in cell culture medium. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 541-4. PMID 19448747 DOI: 10.1139/o09-011 |
0.656 |
|
| 2009 |
Olszewski KL, Morrisey JM, Wilinski D, Burns JM, Vaidya AB, Rabinowitz JD, Llinás M. Host-parasite interactions revealed by Plasmodium falciparum metabolomics. Cell Host & Microbe. 5: 191-9. PMID 19218089 DOI: 10.1016/J.Chom.2009.01.004 |
0.81 |
|
| 2009 |
van Brummelen AC, Olszewski KL, Wilinski D, Llinás M, Louw AI, Birkholtz LM. Co-inhibition of Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase reveals perturbation-specific compensatory mechanisms by transcriptome, proteome, and metabolome analyses. The Journal of Biological Chemistry. 284: 4635-46. PMID 19073607 DOI: 10.1074/Jbc.M807085200 |
0.754 |
|
| 2008 |
Llinás M, Deitsch KW, Voss TS. Plasmodium gene regulation: far more to factor in. Trends in Parasitology. 24: 551-6. PMID 18929512 DOI: 10.1016/J.Pt.2008.08.010 |
0.454 |
|
| 2008 |
Tamez PA, Bhattacharjee S, van Ooij C, Hiller NL, Llinás M, Balu B, Adams JH, Haldar K. An erythrocyte vesicle protein exported by the malaria parasite promotes tubovesicular lipid import from the host cell surface. Plos Pathogens. 4: e1000118. PMID 18688278 DOI: 10.1371/Journal.Ppat.1000118 |
0.488 |
|
| 2008 |
De Silva EK, Gehrke AR, Olszewski K, León I, Chahal JS, Bulyk ML, Llinás M. Specific DNA-binding by apicomplexan AP2 transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 105: 8393-8. PMID 18541913 DOI: 10.1073/Pnas.0801993105 |
0.809 |
|
| 2008 |
Birkholtz L, van Brummelen AC, Clark K, Niemand J, Maréchal E, Llinás M, Louw AI. Exploring functional genomics for drug target and therapeutics discovery in Plasmodia. Acta Tropica. 105: 113-23. PMID 18083131 DOI: 10.1016/J.Actatropica.2007.10.013 |
0.35 |
|
| 2007 |
Hu G, Llinás M, Li J, Preiser PR, Bozdech Z. Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy. Bmc Bioinformatics. 8: 350. PMID 17880708 DOI: 10.1186/1471-2105-8-350 |
0.336 |
|
| 2007 |
Deitsch K, Duraisingh M, Dzikowski R, Gunasekera A, Khan S, Le Roch K, Llinás M, Mair G, McGovern V, Roos D, Shock J, Sims J, Wiegand R, Winzeler E. Mechanisms of gene regulation in Plasmodium. The American Journal of Tropical Medicine and Hygiene. 77: 201-8. PMID 17690387 |
0.773 |
|
| 2007 |
Cellitti J, Llinas M, Echols N, Shank EA, Gillespie B, Kwon E, Crowder SM, Dahlquist FW, Alber T, Marqusee S. Exploring subdomain cooperativity in T4 lysozyme I: structural and energetic studies of a circular permutant and protein fragment. Protein Science : a Publication of the Protein Society. 16: 842-51. PMID 17400926 DOI: 10.1110/Ps.062628607 |
0.762 |
|
| 2006 |
Llinás M, Bozdech Z, Wong ED, Adai AT, DeRisi JL. Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains. Nucleic Acids Research. 34: 1166-73. PMID 16493140 DOI: 10.1093/Nar/Gkj517 |
0.516 |
|
| 2005 |
Llinás M, del Portillo HA. Mining the malaria transcriptome. Trends in Parasitology. 21: 350-2. PMID 15979411 DOI: 10.1016/J.Pt.2005.06.009 |
0.426 |
|
| 2005 |
Vranken WF, Boucher W, Stevens TJ, Fogh RH, Pajon A, Llinas M, Ulrich EL, Markley JL, Ionides J, Laue ED. The CCPN data model for NMR spectroscopy: development of a software pipeline. Proteins. 59: 687-96. PMID 15815974 DOI: 10.1002/Prot.20449 |
0.331 |
|
| 2004 |
Galgoczy DJ, Cassidy-Stone A, Llinás M, O'Rourke SM, Herskowitz I, DeRisi JL, Johnson AD. Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 101: 18069-74. PMID 15604142 DOI: 10.1073/Pnas.0407611102 |
0.5 |
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| 2004 |
Llinás M, DeRisi JL. Pernicious plans revealed: Plasmodium falciparum genome wide expression analysis. Current Opinion in Microbiology. 7: 382-7. PMID 15358256 DOI: 10.1016/J.Mib.2004.06.014 |
0.601 |
|
| 2003 |
Bozdech Z, Llinás M, Pulliam BL, Wong ED, Zhu J, DeRisi JL. The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. Plos Biology. 1: E5. PMID 12929205 DOI: 10.1371/Journal.Pbio.0000005 |
0.669 |
|
| 1999 |
Llinás M, Gillespie B, Dahlquist FW, Marqusee S. The energetics of T4 lysozyme reveal a hierarchy of conformations. Nature Structural Biology. 6: 1072-8. PMID 10542101 DOI: 10.1038/14956 |
0.539 |
|
| 1999 |
Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL. Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 38: 5362-77. PMID 10220323 DOI: 10.1021/Bi982878X |
0.624 |
|
| 1998 |
Llinás M, Marqusee S. Subdomain interactions as a determinant in the folding and stability of T4 lysozyme. Protein Science : a Publication of the Protein Society. 7: 96-104. PMID 9514264 DOI: 10.1002/Pro.5560070110 |
0.558 |
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