Christoph J. Binder, Ph.D. - Publications

Affiliations: 
2002 University of California, San Diego, La Jolla, CA 
Area:
Immunology, Pathology, Animal Physiology Biology

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Taleb A, Willeit P, Amir S, Perkmann T, Kozma MO, Watzenböck ML, Binder CJ, Witztum JL, Tsimikas S. High Immunoglobulin-M Levels to Oxidation-Specific Epitopes Are Associated with Lower Risk of Acute Myocardial Infarction. Journal of Lipid Research. 100391. PMID 37211249 DOI: 10.1016/j.jlr.2023.100391  0.428
2022 Srikakulapu P, Pattarabanjird T, Upadhye A, Bontha SV, Osinski V, Marshall MA, Garmey J, Deroissart J, Prohaska TA, Witztum JL, Binder CJ, Holodick NE, Rothstein TL, McNamara CA. B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis. Frontiers in Immunology. 13: 909475. PMID 35935999 DOI: 10.3389/fimmu.2022.909475  0.406
2021 Porsch F, Mallat Z, Binder CJ. Humoral immunity in atherosclerosis and myocardial infarction: from B cells to antibodies. Cardiovascular Research. PMID 34450620 DOI: 10.1093/cvr/cvab285  0.312
2020 Hofheinz K, Seibert F, Ackermann JA, Dietel B, Tauchi M, Oszvar-Kozma M, Kühn H, Schett G, Binder CJ, Krönke G. Formation of atherosclerotic lesions is independent of eosinophils in male mice. Atherosclerosis. 311: 67-72. PMID 32947200 DOI: 10.1016/J.Atherosclerosis.2020.08.030  0.434
2020 Nus M, Basatemur G, Galan M, Cros-Brunsó L, Zhao TX, Masters L, Harrison J, Figg N, Tsiantoulas D, Geissmann F, Binder CJ, Sage AP, Mallat Z. NR4A1 Deletion in Marginal Zone B Cells Exacerbates Atherosclerosis in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314607. PMID 32907369 DOI: 10.1161/Atvbaha.120.314607  0.374
2020 Nicolai O, Pötschke C, Raafat D, van der Linde J, Quosdorf S, Laqua A, Heidecke CD, Berek C, Darisipudi MN, Binder CJ, Bröker BM. Oxidation-Specific Epitopes (OSEs) Dominate the B Cell Response in Murine Polymicrobial Sepsis. Frontiers in Immunology. 11: 1570. PMID 32849533 DOI: 10.3389/Fimmu.2020.01570  0.404
2020 Mussbacher M, Salzmann M, Haigl B, Basílio J, Hochreiter B, Gleitsmann V, Moser B, Hoesel B, Suur BE, Puhm F, Ungerböck C, Kuttke M, Forteza MJ, Binder CJ, Ketelhuth DFJ, et al. Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis. Atherosclerosis. 307: 21-31. PMID 32711212 DOI: 10.1016/J.Atherosclerosis.2020.06.005  0.301
2020 Zernecke A, Winkels H, Cochain C, Williams JW, Wolf D, Soehnlein O, Robbins CS, Monaco C, Park I, McNamara CA, Binder CJ, Cybulsky MI, Scipione CA, Hedrick CC, Galkina EV, et al. Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas. Circulation Research. 127: 402-426. PMID 32673538 DOI: 10.1161/Circresaha.120.316903  0.35
2020 Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, ... ... Binder CJ, et al. The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science Immunology. 5. PMID 32646852 DOI: 10.1126/Sciimmunol.Abc3979  0.35
2020 Biswas TK, VanderLaan PA, Que X, Gonen A, Krishack P, Binder CJ, Witztum JL, Getz GS, Reardon CA. CD1d Selectively Down Regulates the Expression of the Oxidized Phospholipid-Specific E06 IgM Natural Antibody in Mice. Antibodies (Basel, Switzerland). 9. PMID 32635160 DOI: 10.3390/Antib9030030  0.571
2020 Douna H, Amersfoort J, Schaftenaar FH, Kröner MJ, Kiss MG, Slütter B, Depuydt MAC, Bernabé Kleijn MNA, Wezel A, Smeets HJ, Yagita H, Binder CJ, Bot I, van Puijvelde GHM, Kuiper J, et al. B- and T-lymphocyte attenuator stimulation protects against atherosclerosis by regulating follicular B cells. Cardiovascular Research. 116: 295-305. PMID 31150053 DOI: 10.1093/Cvr/Cvz129  0.368
2019 Clément M, Raffort J, Lareyre F, Tsiantoulas D, Newland SA, Lu Y, Masters L, Harrison J, Saveljeva S, Ma MK, Ozsvar-Kozma M, Lam B, Yeo GS, Binder CJ, Kaser A, et al. Impaired Autophagy in CD11b Dendritic Cells Expands CD4 Regulatory T Cells And Limits Atherosclerosis in Mice. Circulation Research. PMID 31610723 DOI: 10.1161/Circresaha.119.315248  0.376
2019 Kiss MG, Ozsvár-Kozma M, Porsch F, Göderle L, Papac-Miličević N, Bartolini-Gritti B, Tsiantoulas D, Pickering MC, Binder CJ. Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production. Frontiers in Immunology. 10: 1607. PMID 31354740 DOI: 10.3389/Fimmu.2019.01607  0.364
2019 Porsch F, Binder CJ. Impact of B-Cell-Targeted Therapies on Cardiovascular Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119311996. PMID 31315439 DOI: 10.1161/Atvbaha.119.311996  0.332
2019 Ketelhuth DFJ, Lutgens E, Bäck M, Binder CJ, Van den Bossche J, Daniel C, Dumitriu IE, Hoefer I, Libby P, O'Neill L, Weber C, Evans P. Immunometabolism and atherosclerosis: perspectives and clinical significance- A position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. Cardiovascular Research. PMID 31228191 DOI: 10.1093/Cvr/Cvz166  0.368
2019 Puhm F, Afonyushkin T, Resch U, Obermayer G, Rohde M, Penz T, Schuster M, Wagner G, Rendeiro AF, Melki I, Kaun C, Wojta J, Bock C, Jilma B, Mackman N, ... ... Binder CJ, et al. Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells. Circulation Research. 125: 43-52. PMID 31219742 DOI: 10.1161/Circresaha.118.314601  0.329
2019 Bagchi-Chakraborty J, Francis A, Bray T, Masters L, Tsiantoulas D, Nus M, Harrison J, Broekhuizen M, Leggat J, Clatworthy MR, Espeli M, Smith KGC, Binder CJ, Mallat Z, Sage AP. B Cell Fcγ Receptor IIb Modulates Atherosclerosis in Male and Female Mice by Controlling Adaptive Germinal Center and Innate B1-Cell Responses. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312272. PMID 31092015 DOI: 10.1161/Atvbaha.118.312272  0.364
2019 Centa M, Jin H, Hofste L, Hellberg S, Busch A, Baumgartner R, Verzaal NJ, Lind Enoksson S, Perisic Matic L, Boddul SV, Atzler D, Li DY, Sun C, Hansson GK, Ketelhuth DFJ, ... ... Binder CJ, et al. Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability. Circulation. PMID 30894016 DOI: 10.1161/Circulationaha.118.038534  0.378
2019 Yin C, Ackermann S, Ma Z, Mohanta SK, Zhang C, Li Y, Nietzsche S, Westermann M, Peng L, Hu D, Bontha SV, Srikakulapu P, Beer M, Megens RTA, Steffens S, ... ... Binder CJ, et al. ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine. PMID 30692699 DOI: 10.1038/S41591-018-0336-8  0.348
2019 Douna H, Amersfoort J, Schaftenaar F, Bot I, Binder C, Yagita H, van Puijvelde G, Kuiper J, Foks A. Btla Stimulation Protects Against Atherosclerosis By Regulating Follicular B Cells Atherosclerosis. 287: e100. DOI: 10.1016/J.Atherosclerosis.2019.06.290  0.305
2019 Porsch F, Kiss M, Tsiantoulas D, Goederle L, Ozsvar-Kozma M, Nitschke L, Mallat Z, Binder CJ. Global And Haematopoietic Cd22 Deficiency In Ldlr-/- Mice Reduce Plasma Triglyceride And Cholesterol Levels Without Affecting Lesion Formation Atherosclerosis. 287. DOI: 10.1016/J.Atherosclerosis.2019.06.066  0.301
2018 Houben T, Magro Dos Reis I, Oligschlaeger Y, Steinbusch H, Gijbels MJJ, Hendrikx T, Binder CJ, Cassiman D, Westerterp M, Prickaerts J, Shiri-Sverdlov R. Pneumococcal Immunization Reduces Neurological and Hepatic Symptoms in a Mouse Model for Niemann-Pick Type C1 Disease. Frontiers in Immunology. 9: 3089. PMID 30666257 DOI: 10.3389/Fimmu.2018.03089  0.373
2018 Sage AP, Tsiantoulas D, Binder CJ, Mallat Z. The role of B cells in atherosclerosis. Nature Reviews. Cardiology. PMID 30410107 DOI: 10.1038/S41569-018-0106-9  0.436
2018 Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, ... ... Binder CJ, et al. Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. PMID 30013121 DOI: 10.1038/S41586-018-0313-X  0.466
2018 Centa M, Prokopec KE, Garimella MG, Habir K, Hofste L, Stark JM, Dahdah A, Tibbit CA, Polyzos KA, Gisterå A, Johansson DK, Maeda NN, Hansson GK, Ketelhuth DFJ, Coquet JM, ... Binder CJ, et al. Acute Loss of Apolipoprotein E Triggers an Autoimmune Response That Accelerates Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29880490 DOI: 10.1161/Atvbaha.118.310802  0.326
2018 Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, ... ... Binder CJ, et al. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature. PMID 29875409 DOI: 10.1038/S41586-018-0198-8  0.545
2018 Tsiantoulas D, Sage AP, Göderle L, Ozsvar-Kozma M, Murphy D, Porsch F, Pasterkamp G, Menche J, Schneider P, Mallat Z, Binder CJ. BAFF Neutralization Aggravates Atherosclerosis. Circulation. PMID 29858401 DOI: 10.1161/Circulationaha.117.032790  0.419
2018 Clément M, Haddad Y, Raffort J, Lareyre F, Newland SA, Masters L, Harrison J, Ozsvar Kozma M, Bruneval P, Binder CJ, Taleb S, Mallat Z. Deletion of IRF8-Dependent Dendritic Cells Abrogates Pro-Atherogenic Adaptive Immunity. Circulation Research. PMID 29436389 DOI: 10.1161/Circresaha.118.312713  0.391
2018 Obermayer G, Afonyushkin T, Binder CJ. Oxidized low density lipoprotein in inflammation-driven thrombosis. Journal of Thrombosis and Haemostasis : Jth. PMID 29316215 DOI: 10.1111/Jth.13925  0.386
2018 Porsch F, Kiss M, Tsiantoulas D, Goederle L, Ozsvar-Kozma M, Binder CJ. P379CD22 deficiency alters B cell populations and plasma triglyceride levels but does not affect atherosclerosis in hyperlipidemic mice Cardiovascular Research. 114: S96-S96. DOI: 10.1093/Cvr/Cvy060.288  0.319
2018 Kiss M, Tsiantoulas D, Papac-Milicevic N, Goderle L, Ozsvar-Kozma M, Hendrikx T, Bartolini Gritti B, Porsch F, Swirski FK, Binder CJ. 14Hematopoietic complement factor H deficiency elevates plasma IgM levels and reduces atherosclerotic lesion formation in Ldlr deficient mice Cardiovascular Research. 114: S3-S3. DOI: 10.1093/Cvr/Cvy060.004  0.303
2018 Even G, Kiss M, Laschet J, Ozvar Kozma M, Simon T, Wigren M, Gaston A, Procopio E, Le Borgne-Moynnier M, Nilsson J, Kuiper J, Nicoletti A, Binder C, Caligiuri G. Vaccination with Prevenar® boosts the production of anti-phosphorylcholine antibodies and protects APOE knockout mice from atherosclerosis Atherosclerosis. 275: e6-e7. DOI: 10.1016/J.Atherosclerosis.2018.06.903  0.321
2018 Kiss M, Porsch F, Hladik A, Göderle L, Sharif O, Knapp S, Binder C. TREM2 deficiency increases plasma cholesterol and triglyceride levels without influencing lesion formation in LDLR-deficient mice Atherosclerosis. 275: e155-e156. DOI: 10.1016/J.Atherosclerosis.2018.06.464  0.31
2017 Nus M, Sage AP, Lu Y, Masters L, Lam BY, Newland S, Weller S, Tsiantoulas D, Raffort J, Marcus D, Finigan A, Kitt L, Figg N, Schirmbeck R, Kneilling M, ... ... Binder CJ, et al. Marginal Zone B cells control follicular helper T cell response to high cholesterol diet. Atherosclerosis. 263: e12-e13. PMID 29365488 DOI: 10.1016/J.Atherosclerosis.2017.06.067  0.315
2017 Eichinger S, Kyrle PA, Kammer M, Eischer L, Ozsvar Kozma M, Binder CJ. Natural antibodies to oxidation-specific epitopes: innate immune response and venous thromboembolic disease. Journal of Thrombosis and Haemostasis : Jth. 16: 31-35. PMID 29045005 DOI: 10.1111/Jth.13874  0.384
2017 Houben T, Oligschlaeger Y, Bitorina AV, Hendrikx T, Walenbergh SMA, Lenders MH, Gijbels MJJ, Verheyen F, Lütjohann D, Hofker MH, Binder CJ, Shiri-Sverdlov R. Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation. Scientific Reports. 7: 12550. PMID 28970532 DOI: 10.1038/S41598-017-13058-Z  0.346
2017 Meeuwsen JAL, van Duijvenvoorde A, Gohar A, Kozma MO, van de Weg SM, Gijsberts CM, Haitjema S, Björkbacka H, Fredrikson GN, de Borst GJ, den Ruijter HM, Pasterkamp G, Binder CJ, Hoefer IE, de Jager SCA. High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease. Journal of the American Heart Association. 6. PMID 28882820 DOI: 10.1161/Jaha.117.005747  0.332
2017 Puhm F, Binder CJ. Characterization of Natural IgM Antibodies Recognizing Oxidation-Specific Epitopes on Circulating Microvesicles. Methods in Molecular Biology (Clifton, N.J.). 1643: 147-154. PMID 28667535 DOI: 10.1007/978-1-4939-7180-0_11  0.341
2017 Ponnuswamy P, Joffre J, Herbin O, Esposito B, Laurans L, Binder CJ, Tedder TF, Zeboudj L, Loyer X, Giraud A, Zhang Y, Tedgui A, Mallat Z, Ait-Oufella H. Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells. Scientific Reports. 7: 4111. PMID 28646220 DOI: 10.1038/S41598-017-04438-6  0.336
2017 Sage AP, Nus M, Bagchi Chakraborty J, Tsiantoulas D, Newland SA, Finigan AJ, Masters L, Binder CJ, Mallat Z. X-Box Binding Protein-1 Dependent Plasma Cell Responses Limit the Development of Atherosclerosis. Circulation Research. PMID 28620068 DOI: 10.1161/Circresaha.117.310884  0.421
2017 Tsiantoulas D, Kiss M, Bartolini-Gritti B, Bergthaler A, Mallat Z, Jumaa H, Binder CJ. Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development. Scientific Reports. 7: 3540. PMID 28615655 DOI: 10.1038/S41598-017-03688-8  0.348
2017 Newland SA, Mohanta S, Clément M, Taleb S, Walker JA, Nus M, Sage AP, Yin C, Hu D, Kitt LL, Finigan AJ, Rodewald HR, Binder CJ, McKenzie ANJ, Habenicht AJ, et al. Type-2 innate lymphoid cells control the development of atherosclerosis in mice. Nature Communications. 8: 15781. PMID 28589929 DOI: 10.1038/Ncomms15781  0.309
2017 Jäckel S, Kiouptsi K, Lillich M, Hendrikx T, Khandagale A, Kollar B, Hörmann N, Reiss C, Subramaniam S, Wilms E, Ebner K, von Brühl ML, Rausch P, Baines JF, Haberichter S, ... ... Binder CJ, et al. Gut microbiota regulate hepatic von Willebrand Factor synthesis and arterial thrombus formation via Toll-like receptor-2. Blood. PMID 28572286 DOI: 10.1182/Blood-2016-11-754416  0.331
2017 Nus M, Sage AP, Lu Y, Masters L, Lam BYH, Newland S, Weller S, Tsiantoulas D, Raffort J, Marcus D, Finigan A, Kitt L, Figg N, Schirmbeck R, Kneilling M, ... ... Binder CJ, et al. Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet. Nature Medicine. PMID 28414328 DOI: 10.1038/Nm.4315  0.383
2017 Olsson AG, Angelin B, Assmann G, Binder CJ, Björkhem I, Cedazo-Minguez A, Cohen J, von Eckardstein A, Farinaro E, Müller-Wieland D, Parhofer KG, Parini P, Rosenson RS, Starup-Linde J, Tikkanen MJ, et al. Can LDL cholesterol be too low? Possible risks of extremely low levels. Journal of Internal Medicine. PMID 28295777 DOI: 10.1111/Joim.12614  0.312
2017 Binder CJ. Lipid modification and lipid peroxidation products in innate immunity and inflammation. Biochimica Et Biophysica Acta. PMID 28110101 DOI: 10.1016/J.Bbalip.2017.01.006  0.33
2016 Busch CJ, Hendrikx T, Weismann D, Jäckel S, Walenbergh SM, Rendeiro AF, Weißer J, Puhm F, Hladik A, Göderle L, Papac-Milicevic N, Haas G, Millischer V, Subramaniam S, Knapp S, ... ... Binder CJ, et al. Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. Hepatology (Baltimore, Md.). PMID 27981604 DOI: 10.1002/Hep.28970  0.314
2016 Tsiantoulas D, Bot I, Ozsvar Kozma M, Goederle L, Perkmann T, Hartvigsen K, Conrad DH, Kuiper J, Mallat Z, Binder CJ. Increased Plasma IgE Accelerate Atherosclerosis in Secreted IgM Deficiency. Circulation Research. PMID 27903567 DOI: 10.1161/Circresaha.116.309606  0.421
2016 Wolfram W, Sauerwein KM, Binder CJ, Eibl-Musil N, Wolf HM, Fischer MB. Pneumococcal Polysaccharide Vaccination Elicits IgG Anti-A/B Blood Group Antibodies in Healthy Individuals and Patients with Type I Diabetes Mellitus. Frontiers in Immunology. 7: 493. PMID 27895641 DOI: 10.3389/Fimmu.2016.00493  0.346
2016 Jeurissen ML, Walenbergh SM, Houben T, Gijbels MJ, Li J, Hendrikx T, Oligschlaeger Y, van Gorp PJ, Binder CJ, Donners MM, Shiri-Sverdlov R. Prevention of oxLDL uptake leads to decreased atherosclerosis in hematopoietic NPC1-deficient Ldlr(-/-) mice. Atherosclerosis. 255: 59-65. PMID 27816810 DOI: 10.1016/J.Atherosclerosis.2016.10.038  0.399
2016 Hendrikx T, Watzenböck ML, Walenbergh SM, Amir S, Gruber S, Kozma MO, Grabsch HI, Koek GH, Pierik MJ, Staufer K, Trauner M, Kalhan SC, Jonkers D, Hofker MH, Binder CJ, et al. Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease. Bmc Medicine. 14: 107. PMID 27443391 DOI: 10.1186/S12916-016-0652-0  0.358
2016 Busch CJ, Binder CJ. Malondialdehyde epitopes as mediators of sterile inflammation. Biochimica Et Biophysica Acta. PMID 27355566 DOI: 10.1016/J.Bbalip.2016.06.016  0.414
2016 Binder CJ, Papac-Milicevic N, Witztum JL. Innate sensing of oxidation-specific epitopes in health and disease. Nature Reviews. Immunology. PMID 27346802 DOI: 10.1038/Nri.2016.63  0.547
2016 Papac-Milicevic N, Busch CJ, Binder CJ. Malondialdehyde Epitopes as Targets of Immunity and the Implications for Atherosclerosis. Advances in Immunology. 131: 1-59. PMID 27235680 DOI: 10.1016/Bs.Ai.2016.02.001  0.427
2016 Gruber S, Hendrikx T, Tsiantoulas D, Ozsvar-Kozma M, Göderle L, Mallat Z, Witztum JL, Shiri-Sverdlov R, Nitschke L, Binder CJ. Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells. Cell Reports. 14: 2348-61. PMID 26947073 DOI: 10.1016/J.Celrep.2016.02.027  0.558
2016 Grimm M, Tischner D, Troidl K, Albarrán Juárez J, Sivaraj KK, Ferreirós Bouzas N, Geisslinger G, Binder CJ, Wettschureck N. S1P2/G12/13 Signaling Negatively Regulates Macrophage Activation and Indirectly Shapes the Atheroprotective B1-Cell Population. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 37-48. PMID 26603156 DOI: 10.1161/Atvbaha.115.306066  0.317
2016 Bartolini Gritti B, Binder CJ. Oxidation-specific epitopes are major targets of innate immunity in atherothrombosis. HäMostaseologie. 36: 89-96. PMID 25682990 DOI: 10.5482/Hamo-14-11-0069  0.476
2016 Obermayer G, Afonyushkin T, Puhm F, Schwameis M, Jilma B, Binder CJ. Natural IgM Against Oxidation-Specific Epitopes Inhibit Microvesicle-Driven Coagulation Blood. 128: 2562-2562. DOI: 10.1182/Blood.V128.22.2562.2562  0.409
2016 Hendrikx T, Watzenboeck M, Walenbergh S, Kalhan S, Koek G, Jonkers D, Binder C, Shiri-Sverdlov R. Low Levels of Natural IGM Antibodies Towards Oxidation-Specific Epitopes are Associated with Human Non-Alcoholic Steatohepatitis Journal of Hepatology. 64: S501. DOI: 10.1016/S0168-8278(16)00865-5  0.312
2016 Papac-Milicevic N, Mohlin FC, Weismann D, Ademi M, Busch CJ, Rebsamen M, Gritti BB, Gorna M, Kiss M, Alic L, Blom AM, Binder CJ. Malondialdehyde epitopes act as hubs for complement activation on dying cells Immunobiology. 221: 1147-1148. DOI: 10.1016/J.Imbio.2016.06.053  0.303
2016 Gruber S, Hendrikx T, Tsiantoulas D, Ozsvar-Kozma M, Göderle L, Mallat Z, Witztum JL, Shiri-Sverdlov R, Nitschke L, Binder CJ. Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells Cell Reports. 14: 2348-2361. DOI: 10.1016/j.celrep.2016.02.027  0.501
2016 Tsiantoulas D, Bot I, Kiss M, Bartolini-Gritti B, Göderle L, Ozsvar-Kozma M, Perkmann T, Hartvigsen K, Bergthaler A, Conrad D, Kuiper J, Mallat Z, Jumaa H, Binder C. Deficiency of secreted IgM antibodies causes increased plasma IgE levels that promote atherosclerosis Atherosclerosis. 252: e263. DOI: 10.1016/J.Atherosclerosis.2016.07.097  0.32
2016 Papac-Milicevic N, Busch CJL, Binder CJ. Malondialdehyde Epitopes as Targets of Immunity and the Implications for Atherosclerosis Advances in Immunology. DOI: 10.1016/bs.ai.2016.02.001  0.316
2015 Centa M, Gruber S, Nilsson D, Polyzos KA, Johansson DK, Hansson GK, Ketelhuth DF, Binder CJ, Malin S. Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26564818 DOI: 10.1161/Atvbaha.115.305990  0.302
2015 Übelhart R, Hug E, Bach MP, Wossning T, Dühren-von Minden M, Horn AH, Tsiantoulas D, Kometani K, Kurosaki T, Binder CJ, Sticht H, Nitschke L, Reth M, Jumaa H. Responsiveness of B cells is regulated by the hinge region of IgD. Nature Immunology. 16: 534-43. PMID 25848865 DOI: 10.1038/Ni.3141  0.367
2015 Aprahamian TR, Zhong X, Amir S, Binder CJ, Chiang LK, Al-Riyami L, Gharakhanian R, Harnett MM, Harnett W, Rifkin IR. The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model. International Journal For Parasitology. 45: 203-7. PMID 25666929 DOI: 10.1016/J.Ijpara.2014.12.006  0.32
2015 Tsiantoulas D, Perkmann T, Afonyushkin T, Mangold A, Prohaska TA, Papac-Milicevic N, Millischer V, Bartel C, Hörkkö S, Boulanger CM, Tsimikas S, Fischer MB, Witztum JL, Lang IM, Binder CJ. Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies. Journal of Lipid Research. 56: 440-8. PMID 25525116 DOI: 10.1194/Jlr.P054569  0.555
2015 Tsiantoulas D, Sage AP, Mallat Z, Binder CJ. Targeting B cells in atherosclerosis: closing the gap from bench to bedside. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 296-302. PMID 25359862 DOI: 10.1161/Atvbaha.114.303569  0.357
2015 Walenbergh S, Houben T, Hendrikx T, van Gorp P, Jeurissen M, Bieghs V, Lenders M, Gijbels M, Plat J, Hofker M, Binder C, Luetjohann D, Verheyen F, Koek G, Shiri-Sverdlov R. O068 : Lysosomal cholesterol in kupffer cells, particularly when oxidized, contributes to murine steatohepatitis Journal of Hepatology. 62: S224-S225. DOI: 10.1016/S0168-8278(15)30082-9  0.327
2014 Gonen A, Hansen LF, Turner WW, Montano EN, Que X, Rafia A, Chou MY, Wiesner P, Tsiantoulas D, Corr M, VanNieuwenhze MS, Tsimikas S, Binder CJ, Witztum JL, Hartvigsen K. Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccine. Journal of Lipid Research. 55: 2137-55. PMID 25143462 DOI: 10.1194/Jlr.M053256  0.539
2014 Tsiantoulas D, Diehl CJ, Witztum JL, Binder CJ. B cells and humoral immunity in atherosclerosis. Circulation Research. 114: 1743-56. PMID 24855199 DOI: 10.1161/Circresaha.113.301145  0.539
2014 Wolf D, Jehle F, Michel NA, Bukosza EN, Rivera J, Chen YC, Hoppe N, Dufner B, Rodriguez AO, Colberg C, Nieto L, Rupprecht B, Wiedemann A, Schulte L, Peikert A, ... ... Binder CJ, et al. Coinhibitory suppression of T cell activation by CD40 protects against obesity and adipose tissue inflammation in mice. Circulation. 129: 2414-25. PMID 24664276 DOI: 10.1161/Circulationaha.113.008055  0.307
2014 Schuh C, Wimmer I, Hametner S, Haider L, Van Dam AM, Liblau RS, Smith KJ, Probert L, Binder CJ, Bauer J, Bradl M, Mahad D, Lassmann H. Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models. Acta Neuropathologica. 128: 247-66. PMID 24622774 DOI: 10.1007/S00401-014-1263-5  0.338
2014 Eichinger S, Kyrle PA, Kammer M, Eischer L, Binder C. Naturally Occurring Autoantibodies to Oxidation-Specific Epitopes in Patients with Venous Thromboembolism Blood. 124: 2861-2861. DOI: 10.1182/Blood.V124.21.2861.2861  0.327
2013 Hendrikx T, Bieghs V, Walenbergh SM, van Gorp PJ, Verheyen F, Jeurissen ML, Steinbusch MM, Vaes N, Binder CJ, Koek GH, Stienstra R, Netea MG, Hofker MH, Shiri-Sverdlov R. Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice. Plos One. 8: e78792. PMID 24312444 DOI: 10.1371/Journal.Pone.0078792  0.305
2013 Karper JC, de Jager SC, Ewing MM, de Vries MR, Bot I, van Santbrink PJ, Redeker A, Mallat Z, Binder CJ, Arens R, Jukema JW, Kuiper J, Quax PH. An unexpected intriguing effect of Toll-like receptor regulator RP105 (CD180) on atherosclerosis formation with alterations on B-cell activation. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2810-7. PMID 24115036 DOI: 10.1161/Atvbaha.113.301882  0.353
2013 Zouggari Y, Ait-Oufella H, Bonnin P, Simon T, Sage AP, Guérin C, Vilar J, Caligiuri G, Tsiantoulas D, Laurans L, Dumeau E, Kotti S, Bruneval P, Charo IF, Binder CJ, et al. B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction. Nature Medicine. 19: 1273-80. PMID 24037091 DOI: 10.1038/Nm.3284  0.302
2013 Montano EN, Boullier A, Almazan F, Binder CJ, Witztum JL, Hartvigsen K. Development and application of a nonradioactive binding assay of oxidized low-density lipoprotein to macrophage scavenger receptors Journal of Lipid Research. 54: 3206-3214. PMID 23997238 DOI: 10.1194/Jlr.D040923  0.51
2013 Matt U, Sharif O, Martins R, Furtner T, Langeberg L, Gawish R, Elbau I, Zivkovic A, Lakovits K, Oskolkova O, Doninger B, Vychytil A, Perkmann T, Schabbauer G, Binder CJ, et al. WAVE1 mediates suppression of phagocytosis by phospholipid-derived DAMPs. The Journal of Clinical Investigation. 123: 3014-24. PMID 23934128 DOI: 10.1172/Jci60681  0.326
2013 Que X, Widhopf GF, Amir S, Hartvigsen K, Hansen LF, Woelkers D, Tsimikas S, Binder CJ, Kipps TJ, Witztum JL. IGHV1-69-Encoded Antibodies Expressed in Chronic Lymphocytic Leukemia React with Malondialdehyde-Acetaldehyde Adduct, an Immunodominant Oxidation-Specific Epitope Plos One. 8. PMID 23840319 DOI: 10.1371/Journal.Pone.0065203  0.531
2013 Fischer MT, Wimmer I, Höftberger R, Gerlach S, Haider L, Zrzavy T, Hametner S, Mahad D, Binder CJ, Krumbholz M, Bauer J, Bradl M, Lassmann H. Disease-specific molecular events in cortical multiple sclerosis lesions. Brain : a Journal of Neurology. 136: 1799-815. PMID 23687122 DOI: 10.1093/Brain/Awt110  0.322
2013 Bieghs V, Walenbergh SM, Hendrikx T, van Gorp PJ, Verheyen F, Olde Damink SW, Masclee AA, Koek GH, Hofker MH, Binder CJ, Shiri-Sverdlov R. Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation. Liver International : Official Journal of the International Association For the Study of the Liver. 33: 1056-61. PMID 23617943 DOI: 10.1111/Liv.12170  0.346
2013 Lichtman AH, Binder CJ, Tsimikas S, Witztum JL. Adaptive immunity in atherogenesis: new insights and therapeutic approaches. The Journal of Clinical Investigation. 123: 27-36. PMID 23281407 DOI: 10.1172/Jci63108  0.529
2013 Lievens D, Habets KL, Robertson AK, Laouar Y, Winkels H, Rademakers T, Beckers L, Wijnands E, Boon L, Mosaheb M, Ait-Oufella H, Mallat Z, Flavell RA, Rudling M, Binder CJ, et al. Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis European Heart Journal. 34: 3717-3727. PMID 22613345 DOI: 10.1093/Eurheartj/Ehs106  0.317
2012 Tsiantoulas D, Gruber S, Binder CJ. B-1 cell immunoglobulin directed against oxidation-specific epitopes. Frontiers in Immunology. 3: 415. PMID 23316200 DOI: 10.3389/Fimmu.2012.00415  0.443
2012 Cardilo-Reis L, Gruber S, Schreier SM, Drechsler M, Papac-Milicevic N, Weber C, Wagner O, Stangl H, Soehnlein O, Binder CJ. Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype. Embo Molecular Medicine. 4: 1072-86. PMID 23027612 DOI: 10.1002/Emmm.201201374  0.347
2012 Binder CJ. Naturally occurring IgM antibodies to oxidation-specific epitopes. Advances in Experimental Medicine and Biology. 750: 2-13. PMID 22903662 DOI: 10.1007/978-1-4614-3461-0_1  0.404
2012 Amir S, Hartvigsen K, Gonen A, Leibundgut G, Que X, Jensen-Jarolim E, Wagner O, Tsimikas S, Witztum JL, Binder CJ. Peptide mimotopes of malondialdehyde epitopes for clinical applications in cardiovascular disease Journal of Lipid Research. 53: 1316-1326. PMID 22508944 DOI: 10.1194/Jlr.M025445  0.524
2012 Bieghs V, Verheyen F, van Gorp PJ, Hendrikx T, Wouters K, Lütjohann D, Gijbels MJ, Febbraio M, Binder CJ, Hofker MH, Shiri-Sverdlov R. Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. Plos One. 7: e34378. PMID 22470565 DOI: 10.1371/Journal.Pone.0034378  0.334
2012 Papac-Milicevic N, Breuss JM, Zaujec J, Ryban L, Plyushch T, Wagner GA, Fenzl S, Dremsek P, Cabaravdic M, Steiner M, Glass CK, Binder CJ, Uhrin P, Binder BR. The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors. Circulation Research. 110: e50-63. PMID 22427340 DOI: 10.1161/Circresaha.111.258814  0.333
2012 Sage AP, Tsiantoulas D, Baker L, Harrison J, Masters L, Murphy D, Loinard C, Binder CJ, Mallat Z. BAFF receptor deficiency reduces the development of atherosclerosis in mice--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1573-6. PMID 22426131 DOI: 10.1161/Atvbaha.111.244731  0.344
2012 Wolf D, Jehle F, Ortiz Rodriguez A, Dufner B, Hoppe N, Colberg C, Lozhkin A, Bassler N, Rupprecht B, Wiedemann A, Hilgendorf I, Stachon P, Willecke F, Febbraio M, von zur Muhlen C, ... Binder CJ, et al. CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies. Plos One. 7: e33026. PMID 22412980 DOI: 10.1371/Journal.Pone.0033026  0.347
2012 Döring Y, Manthey HD, Drechsler M, Lievens D, Megens RT, Soehnlein O, Busch M, Manca M, Koenen RR, Pelisek J, Daemen MJ, Lutgens E, Zenke M, Binder CJ, Weber C, et al. Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation. 125: 1673-83. PMID 22388324 DOI: 10.1161/Circulationaha.111.046755  0.321
2012 Bieghs V, van Gorp PJ, Walenbergh SM, Gijbels MJ, Verheyen F, Buurman WA, Briles DE, Hofker MH, Binder CJ, Shiri-Sverdlov R. Specific immunization strategies against oxidized low-density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice. Hepatology (Baltimore, Md.). 56: 894-903. PMID 22334337 DOI: 10.1002/Hep.25660  0.444
2012 Weismann D, Binder CJ. The innate immune response to products of phospholipid peroxidation. Biochimica Et Biophysica Acta. 1818: 2465-75. PMID 22305963 DOI: 10.1016/J.Bbamem.2012.01.018  0.429
2012 Bieghs V, Van Gorp PJ, Wouters K, Hendrikx T, Gijbels MJ, van Bilsen M, Bakker J, Binder CJ, Lütjohann D, Staels B, Hofker MH, Shiri-Sverdlov R. LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. Plos One. 7: e30668. PMID 22295101 DOI: 10.1371/Journal.Pone.0030668  0.32
2012 Elsøe S, Ahnström J, Christoffersen C, Hoofnagle AN, Plomgaard P, Heinecke JW, Binder CJ, Björkbacka H, Dahlbäck B, Nielsen LB. Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL. Atherosclerosis. 221: 91-7. PMID 22204862 DOI: 10.1016/J.Atherosclerosis.2011.11.031  0.366
2011 Binder CJ, Witztum JL. Is atherosclerosis an allergic disease? Circulation Research. 109: 1103-4. PMID 22034478 DOI: 10.1161/Res.0B013E31823A8C44  0.53
2011 Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HP, Charbel Issa P, Cano M, Brandstätter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature. 478: 76-81. PMID 21979047 DOI: 10.1038/Nature10449  0.538
2011 Haider L, Fischer MT, Frischer JM, Bauer J, Höftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL, Lassmann H. Oxidative damage in multiple sclerosis lesions. Brain : a Journal of Neurology. 134: 1914-24. PMID 21653539 DOI: 10.1093/Brain/Awr128  0.501
2011 Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, et al. CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. The Journal of Clinical Investigation. 121: 2898-910. PMID 21633167 DOI: 10.1172/Jci44925  0.377
2011 Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K, Boullier A, Gonen A, Diehl CJ, Que X, Montano E, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. Oxidation-specific epitopes are danger-associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circulation Research. 108: 235-48. PMID 21252151 DOI: 10.1161/Circresaha.110.223875  0.561
2011 Wool GD, Cabana VG, Lukens J, Shaw PX, Binder CJ, Witztum JL, Reardon CA, Getz GS. 4F Peptide reduces nascent atherosclerosis and induces natural antibody production in apolipoprotein E-null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 290-300. PMID 20876212 DOI: 10.1096/Fj.10-165670  0.5
2010 Jellusova J, Düber S, Gückel E, Binder CJ, Weiss S, Voll R, Nitschke L. Siglec-G regulates B1 cell survival and selection. Journal of Immunology (Baltimore, Md. : 1950). 185: 3277-84. PMID 20729333 DOI: 10.4049/Jimmunol.1001792  0.318
2010 Ait-Oufella H, Herbin O, Bouaziz JD, Binder CJ, Uyttenhove C, Laurans L, Taleb S, Van Vré E, Esposito B, Vilar J, Sirvent J, Van Snick J, Tedgui A, Tedder TF, Mallat Z. B cell depletion reduces the development of atherosclerosis in mice. The Journal of Experimental Medicine. 207: 1579-87. PMID 20603314 DOI: 10.1084/Jem.20100155  0.411
2010 Binder CJ. Natural IgM antibodies against oxidation-specific epitopes. Journal of Clinical Immunology. 30: S56-60. PMID 20387104 DOI: 10.1007/S10875-010-9396-3  0.341
2010 Cardilo-Reis L, Witztum JL, Binder CJ. When monocytes come (too) close to our hearts. Journal of the American College of Cardiology. 55: 1639-41. PMID 20378084 DOI: 10.1016/J.Jacc.2009.11.068  0.438
2010 Bieghs V, Wouters K, van Gorp PJ, Gijbels MJ, de Winther MP, Binder CJ, Lütjohann D, Febbraio M, Moore KJ, van Bilsen M, Hofker MH, Shiri-Sverdlov R. Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice. Gastroenterology. 138: 2477-86, 2486.e1-3. PMID 20206177 DOI: 10.1053/J.Gastro.2010.02.051  0.353
2010 Pedersen TX, Binder CJ, Fredrikson GN, Nilsson J, Bro S, Nielsen LB. The pro-inflammatory effect of uraemia overrules the anti-atherogenic potential of immunization with oxidized LDL in apoE-/- mice. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 25: 2486-91. PMID 20164045 DOI: 10.1093/Ndt/Gfq059  0.443
2010 Schwartz-Albiez R, Monteiro RC, Rodriguez M, Binder CJ, Shoenfeld Y. Natural antibodies, intravenous immunoglobulin and their role in autoimmunity, cancer and inflammation. Clinical and Experimental Immunology. 43-50. PMID 19883423 DOI: 10.1111/J.1365-2249.2009.04026.X  0.397
2010 Kelly JA, Griffin ME, Fava RA, Wood SG, Bessette KA, Miller ER, Huber SA, Binder CJ, Witztum JL, Morganelli PM. Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the role of IL-10. Cardiovascular Research. 85: 224-31. PMID 19720605 DOI: 10.1093/Cvr/Cvp300  0.525
2010 Bochkov VN, Oskolkova OV, Birukov KG, Levonen AL, Binder CJ, Stöckl J. Generation and biological activities of oxidized phospholipids. Antioxidants & Redox Signaling. 12: 1009-59. PMID 19686040 DOI: 10.1089/Ars.2009.2597  0.414
2010 Amir S, Binder CJ. Experimental immunotherapeutic approaches for atherosclerosis. Clinical Immunology (Orlando, Fla.). 134: 66-79. PMID 19666239 DOI: 10.1016/J.Clim.2009.07.009  0.363
2009 Chou MY, Fogelstrand L, Hartvigsen K, Hansen LF, Woelkers D, Shaw PX, Choi J, Perkmann T, Bäckhed F, Miller YI, Hörkkö S, Corr M, Witztum JL, Binder CJ. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans Journal of Clinical Investigation. 119: 1335-1349. PMID 19363291 DOI: 10.1172/Jci36800  0.601
2009 Hartvigsen K, Chou MY, Hansen LF, Shaw PX, Tsimikas S, Binder CJ, Witztum JL. The role of innate immunity in atherogenesis Journal of Lipid Research. 50. PMID 19106070 DOI: 10.1194/Jlr.R800100-Jlr200  0.574
2009 Lutz HU, Binder CJ, Kaveri S. Naturally occurring auto-antibodies in homeostasis and disease. Trends in Immunology. 30: 43-51. PMID 19058756 DOI: 10.1016/J.It.2008.10.002  0.317
2008 Sämpi M, Ukkola O, Päivänsalo M, Kesäniemi YA, Binder CJ, Hörkkö S. Plasma interleukin-5 levels are related to antibodies binding to oxidized low-density lipoprotein and to decreased subclinical atherosclerosis. Journal of the American College of Cardiology. 52: 1370-8. PMID 18940525 DOI: 10.1016/J.Jacc.2008.06.047  0.357
2008 Bergmark C, Dewan A, Orsoni A, Merki E, Miller ER, Shin MJ, Binder CJ, Hörkkö S, Krauss RM, Chapman MJ, Witztum JL, Tsimikas S. A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. Journal of Lipid Research. 49: 2230-9. PMID 18594118 DOI: 10.1194/Jlr.M800174-Jlr200  0.494
2008 Chou MY, Hartvigsen K, Hansen LF, Fogelstrand L, Shaw PX, Boullier A, Binder CJ, Witztum JL. Oxidation-specific epitopes are important targets of innate immunity Journal of Internal Medicine. 263: 479-488. PMID 18410591 DOI: 10.1111/J.1365-2796.2008.01968.X  0.581
2008 Bro S, Flyvbjerg A, Binder CJ, Bang CA, Denner L, Olgaard K, Nielsen LB. A neutralizing antibody against receptor for advanced glycation end products (RAGE) reduces atherosclerosis in uremic mice. Atherosclerosis. 201: 274-80. PMID 18371970 DOI: 10.1016/J.Atherosclerosis.2008.01.015  0.34
2008 Binder CJ, Chou MY, Fogelstrand L, Hartvigsen K, Shaw PX, Boullier A, Witztum JL. Natural antibodies in murine atherosclerosis Current Drug Targets. 9: 190-195. PMID 18336236 DOI: 10.2174/138945008783755520  0.522
2007 Binder CJ, Hartvigsen K, Witztum JL. Promise of Immune Modulation to Inhibit Atherogenesis**Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology Journal of the American College of Cardiology. 50: 547-550. PMID 17678739 DOI: 10.1016/J.Jacc.2007.04.054  0.524
2007 Bro S, Binder CJ, Witztum JL, Olgaard K, Nielsen LB. Inhibition of the renin-angiotensin system abolishes the proatherogenic effect of uremia in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1080-6. PMID 17347482 DOI: 10.1161/Atvbaha.107.139634  0.469
2007 Hartvigsen K, Binder CJ, Hansen LF, Rafia A, Juliano J, Hörkkö S, Steinberg D, Palinski W, Witztum JL, Li AC. A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 878-885. PMID 17255537 DOI: 10.1161/01.Atv.0000258790.35810.02  0.49
2007 Isobe H, Perkmann T, Breuss JM, Binder CJ, Boulanger CM, Binder BR. Red Blood Cell Derived Microparticles Are Thrombogenic in Mouse Models of Atherosclerosis. Blood. 110: 3624-3624. DOI: 10.1182/Blood.V110.11.3624.3624  0.313
2006 Binder C, Chang M, Boullier A, Chou M, Shaw P, Hartvigsen K, Hansen L, Woelkers D, Miller Y, Hörkkö S, Witztum J. Th-W46:1 Oxidation of LDL leads its recognition by multiple arcs of innate immunity Atherosclerosis Supplements. 7: 459. DOI: 10.1016/S1567-5688(06)81846-5  0.464
2005 Binder CJ, Shaw PX, Chang MK, Boullier A, Hartvigsen K, Hörkkö S, Miller YI, Woelkers DA, Corr M, Witztum JL. The role of natural antibodies in atherogenesis. Journal of Lipid Research. 46: 1353-63. PMID 15897601 DOI: 10.1194/Jlr.R500005-Jlr200  0.564
2005 Buono C, Binder CJ, Stavrakis G, Witztum JL, Glimcher LH, Lichtman AH. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proceedings of the National Academy of Sciences of the United States of America. 102: 1596-601. PMID 15665085 DOI: 10.1073/Pnas.0409015102  0.54
2005 Binder CJ, Silverman GJ. Natural antibodies and the autoimmunity of atherosclerosis. Springer Seminars in Immunopathology. 26: 385-404. PMID 15609021 DOI: 10.1007/S00281-004-0185-Z  0.426
2004 Chang MK, Binder CJ, Miller YI, Subbanagounder G, Silverman GJ, Berliner JA, Witztum JL. Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory. The Journal of Experimental Medicine. 200: 1359-70. PMID 15583011 DOI: 10.1084/Jem.20031763  0.58
2004 Li AC, Binder CJ, Gutierrez A, Brown KK, Plotkin CR, Pattison JW, Valledor AF, Davis RA, Willson TM, Witztum JL, Palinski W, Glass CK. Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. The Journal of Clinical Investigation. 114: 1564-76. PMID 15578089 DOI: 10.1172/Jci18730  0.524
2004 Binder CJ, Hartvigsen K, Chang MK, Miller M, Broide D, Palinski W, Curtiss LK, Corr M, Witztum JL. IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. The Journal of Clinical Investigation. 114: 427-37. PMID 15286809 DOI: 10.1172/Jci20479  0.568
2004 Reardon CA, Miller ER, Blachowicz L, Lukens J, Binder CJ, Witztum JL, Getz GS. Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice. Journal of Lipid Research. 45: 1347-54. PMID 15102879 DOI: 10.1194/Jlr.M400075-Jlr200  0.585
2003 Miller YI, Chang MK, Binder CJ, Shaw PX, Witztum JL. Oxidized low density lipoprotein and innate immune receptors. Current Opinion in Lipidology. 14: 437-45. PMID 14501582 DOI: 10.1097/00041433-200310000-00004  0.553
2003 Binder CJ, Hörkkö S, Dewan A, Chang MK, Kieu EP, Goodyear CS, Shaw PX, Palinski W, Witztum JL, Silverman GJ. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nature Medicine. 9: 736-43. PMID 12740573 DOI: 10.1016/S0214-9168(03)78944-X  0.595
2003 Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells. The Journal of Biological Chemistry. 278: 1561-8. PMID 12424240 DOI: 10.1074/Jbc.M209634200  0.537
2003 Binder CJ, Witztum JL. Reply to "Humoral immunity and atherosclerosis" Nature Medicine. 9: 244-245. DOI: 10.1038/Nm0303-244  0.509
2002 Binder CJ, Chang MK, Shaw PX, Miller YI, Hartvigsen K, Dewan A, Witztum JL. Innate and acquired immunity in atherogenesis. Nature Medicine. 8: 1218-26. PMID 12411948 DOI: 10.1038/Nm1102-1218  0.519
2002 Chang MK, Binder CJ, Torzewski M, Witztum JL. C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids. Proceedings of the National Academy of Sciences of the United States of America. 99: 13043-8. PMID 12244213 DOI: 10.1073/Pnas.192399699  0.547
2000 Hörkkö S, Binder CJ, Shaw PX, Chang MK, Silverman G, Palinski W, Witztum JL. Immunological responses to oxidized LDL. Free Radical Biology & Medicine. 28: 1771-9. PMID 10946219 DOI: 10.1016/S0891-5849(00)00333-6  0.569
1999 Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C, Witztum JL, Funk CD, Conrad D, Glass CK. Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Nature. 400: 378-82. PMID 10432118 DOI: 10.1038/22572  0.49
1999 Binder CJ, Weiher H, Exner M, Kerjaschki D. Glomerular overproduction of oxygen radicals in Mpv17 gene-inactivated mice causes podocyte foot process flattening and proteinuria: A model of steroid-resistant nephrosis sensitive to radical scavenger therapy. The American Journal of Pathology. 154: 1067-75. PMID 10233845 DOI: 10.1016/S0002-9440(10)65359-X  0.3
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