Michael C. Fitzgerald - Publications

Affiliations: 
Chemistry Duke University, Durham, NC 
Area:
protein folding and stability
Website:
http://fds.duke.edu/db/aas/Chemistry/faculty/michael.c.fitzgerald

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bailey MA, Tang Y, Park HJ, Fitzgerald MC. Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes. Journal of the American Society For Mass Spectrometry. PMID 36802530 DOI: 10.1021/jasms.2c00248  0.341
2022 Wiebelhaus N, Singh N, Zhang P, Craig SL, Beratan DN, Fitzgerald MC. Discovery of the Xenon-Protein Interactome Using Large-Scale Measurements of Protein Folding and Stability. Journal of the American Chemical Society. PMID 35213151 DOI: 10.1021/jacs.1c11900  0.359
2020 Wiebelhaus N, Zaengle-Barone JM, Hwang KK, Franz KJ, Fitzgerald MC. Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in . Acs Chemical Biology. PMID 33305953 DOI: 10.1021/acschembio.0c00900  0.312
2020 Lu KY, Quan B, Sylvester K, Srivastava T, Fitzgerald MC, Derbyshire ER. chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32127489 DOI: 10.1073/Pnas.1913525117  0.401
2020 Cabrera A, Wiebelhaus N, Quan B, Ma R, Meng H, Fitzgerald MC. Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach. Journal of the American Society For Mass Spectrometry. 31: 217-226. PMID 32031398 DOI: 10.1021/Jasms.9B00041  0.439
2019 Cabrera A, Randall TA, Ogburn RN, Mebrahtu B, Johnson JHR, Foo ACY, Fitzgerald MC, Mueller GA. Are allergens more abundant and/or more stable than other proteins in pollens and dust? Allergy. PMID 31749155 DOI: 10.1111/All.14121  0.4
2018 Ma R, Meng H, Wiebelhaus N, Fitzgerald MC. Chemo-Selection Strategy for Limited Proteolysis Experiments on the Proteomic Scale. Analytical Chemistry. PMID 30403842 DOI: 10.1021/Acs.Analchem.8B04122  0.367
2018 Kaur U, Meng H, Liu F, Ma R, Ogburn RN, Johnson JHR, Fitzgerald MC, Jones LM. Proteome-Wide Structural Biology: An Emerging Field for the Structural Analysis of Proteins on the Proteomic Scale. Journal of Proteome Research. PMID 30222357 DOI: 10.1021/Acs.Jproteome.8B00341  0.485
2018 Meng H, Ma R, Fitzgerald MC. Chemical Denaturation and Protein Precipitation Approach for Discovery and Quantitation of Protein-Drug Interactions. Analytical Chemistry. PMID 29995387 DOI: 10.1021/Acs.Analchem.8B01772  0.471
2018 Meng H, Fitzgerald MC. Proteome-Wide Characterization of Phosphorylation-Induced Conformational Changes in Breast Cancer. Journal of Proteome Research. PMID 29332387 DOI: 10.1021/Acs.Jproteome.7B00795  0.422
2017 Ogburn RN, Jin L, Meng H, Fitzgerald MC. Discovery of Tamoxifen and N-Desmethyl Tamoxifen Protein Targets in MCF-7 Cells Using Large-Scale Protein Folding and Stability Measurements. Journal of Proteome Research. PMID 28927269 DOI: 10.1021/Acs.Jproteome.7B00442  0.469
2017 Liu F, Meng H, Fitzgerald MC. Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins using SILAC-SPROX. Journal of Proteome Research. PMID 28673085 DOI: 10.1021/Acs.Jproteome.7B00283  0.413
2016 Roberts JH, Liu F, Karnuta JM, Fitzgerald MC. Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome. Journal of Proteome Research. PMID 27806573 DOI: 10.1021/Acs.Jproteome.6B00927  0.379
2016 Liu F, Fitzgerald MC. Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins using Limited Proteolysis. Journal of Proteome Research. PMID 27794609 DOI: 10.1021/Acs.Jproteome.6B00755  0.376
2016 Ogburn RN, Randall TA, Xu Y, Roberts JH, Mebrahtu B, Karnuta JM, Rider SD, Kissling GE, London RE, Pomés A, Arlian L, Fitzgerald MC, Mueller GA. Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins? The Journal of Allergy and Clinical Immunology. PMID 27771129 DOI: 10.1016/J.Jaci.2016.08.016  0.404
2016 Jin L, Wang D, Gooden DM, Ball C, Fitzgerald MC. Targeted Mass Spectrometry-Based Approach for Protein-Ligand Binding Analyses in Complex Biological Mixtures using a Phenacylbromide Modification Strategy. Analytical Chemistry. PMID 27740755 DOI: 10.1021/Acs.Analchem.6B02658  0.491
2016 Xu Y, Wallace MA, Fitzgerald MC. Thermodynamic Analysis of the Geldanamycin-Hsp90 Interaction in a Whole Cell Lysate Using a Mass Spectrometry-Based Proteomics Approach. Journal of the American Society For Mass Spectrometry. PMID 27530778 DOI: 10.1007/S13361-016-1457-2  0.403
2016 Geer Wallace MA, Kwon DY, Weitzel DH, Lee CT, Stephenson TN, Chi JT, Mook RA, Dewhirst MW, Hong J, Fitzgerald MC. Discovery of Manassantin A Protein Targets using Large-Scale Protein Folding and Stability Measurements. Journal of Proteome Research. PMID 27322910 DOI: 10.1021/Acs.Jproteome.6B00237  0.463
2015 Geer MA, Fitzgerald MC. Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique. Journal of the American Society For Mass Spectrometry. PMID 26530046 DOI: 10.1007/S13361-015-1290-Z  0.457
2015 Adhikari J, West GM, Fitzgerald MC. Global analysis of protein folding thermodynamics for disease state characterization. Journal of Proteome Research. 14: 2287-97. PMID 25825992 DOI: 10.1021/Acs.Jproteome.5B00057  0.687
2014 Adhikari J, Fitzgerald MC. SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding. Journal of the American Society For Mass Spectrometry. 25: 2073-83. PMID 25315461 DOI: 10.1007/S13361-014-0992-Y  0.503
2014 Geer MA, Fitzgerald MC. Energetics-based methods for protein folding and stability measurements. Annual Review of Analytical Chemistry (Palo Alto, Calif.). 7: 209-28. PMID 24896313 DOI: 10.1146/Annurev-Anchem-071213-020024  0.519
2014 Xu Y, Strickland EC, Fitzgerald MC. Thermodynamic analysis of protein folding and stability using a tryptophan modification protocol. Analytical Chemistry. 86: 7041-8. PMID 24896224 DOI: 10.1021/Ac501278J  0.482
2014 Tran DT, Adhikari J, Fitzgerald MC. StableIsotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions. Molecular & Cellular Proteomics : McP. 13: 1800-13. PMID 24741112 DOI: 10.1074/Mcp.M113.034702  0.505
2014 Strickland EC, Geer MA, Hong J, Fitzgerald MC. False-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform. Journal of the American Society For Mass Spectrometry. 25: 132-40. PMID 24114261 DOI: 10.1007/S13361-013-0754-2  0.444
2013 Strickland EC, Geer MA, Tran DT, Adhikari J, West GM, DeArmond PD, Xu Y, Fitzgerald MC. Thermodynamic analysis of protein-ligand binding interactions in complex biological mixtures using the stability of proteins from rates of oxidation. Nature Protocols. 8: 148-61. PMID 23257983 DOI: 10.1038/Nprot.2012.146  0.829
2012 Banerjee S, Siburt CJ, Mistry S, Noto JM, DeArmond P, Fitzgerald MC, Lambert LA, Cornelissen CN, Crumbliss AL. Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport. Metallomics : Integrated Biometal Science. 4: 361-72. PMID 22399131 DOI: 10.1039/C2Mt20037F  0.774
2012 Reichmann D, Xu Y, Cremers CM, Ilbert M, Mittelman R, Fitzgerald MC, Jakob U. Order out of disorder: working cycle of an intrinsically unfolded chaperone. Cell. 148: 947-57. PMID 22385960 DOI: 10.1016/J.Cell.2012.01.045  0.391
2012 Tran DT, Banerjee S, Alayash AI, Crumbliss AL, Fitzgerald MC. Slow histidine H/D exchange protocol for thermodynamic analysis of protein folding and stability using mass spectrometry. Analytical Chemistry. 84: 1653-60. PMID 22185579 DOI: 10.1021/Ac202927P  0.522
2011 Dearmond PD, Xu Y, Strickland EC, Daniels KG, Fitzgerald MC. Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach. Journal of Proteome Research. 10: 4948-58. PMID 21905665 DOI: 10.1021/Pr200403C  0.825
2011 DeArmond PD, West GM, Huang HT, Fitzgerald MC. Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures. Journal of the American Society For Mass Spectrometry. 22: 418-30. PMID 21472561 DOI: 10.1007/S13361-010-0060-1  0.826
2011 Xu Y, Falk IN, Hallen MA, Fitzgerald MC. Mass spectrometry- and lysine amidination-based protocol for thermodynamic analysis of protein folding and ligand binding interactions. Analytical Chemistry. 83: 3555-62. PMID 21456597 DOI: 10.1021/Ac200211T  0.513
2010 Dearmond PD, West GM, Anbalagan V, Campa MJ, Patz EF, Fitzgerald MC. Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy. Journal of Biomolecular Screening. 15: 1051-62. PMID 20855564 DOI: 10.1177/1087057110382775  0.802
2010 Kim H, Baker JB, Park Y, Park HB, DeArmond PD, Kim SH, Fitzgerald MC, Lee DS, Hong J. Total synthesis, assignment of the absolute stereochemistry, and structure-activity relationship studies of subglutinols A and B. Chemistry, An Asian Journal. 5: 1902-10. PMID 20564278 DOI: 10.1002/Asia.201000147  0.741
2010 West GM, Thompson JW, Soderblom EJ, Dubois LG, Dearmond PD, Moseley MA, Fitzgerald MC. Mass spectrometry-based thermal shift assay for protein-ligand binding analysis. Analytical Chemistry. 82: 5573-81. PMID 20527820 DOI: 10.1021/Ac100465A  0.826
2010 West GM, Tucker CL, Xu T, Park SK, Han X, Yates JR, Fitzgerald MC. Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements. Proceedings of the National Academy of Sciences of the United States of America. 107: 9078-82. PMID 20439767 DOI: 10.1073/Pnas.1000148107  0.7
2010 Xu Y, Schmitt S, Tang L, Jakob U, Fitzgerald MC. Thermodynamic analysis of a molecular chaperone binding to unfolded protein substrates. Biochemistry. 49: 1346-53. PMID 20073505 DOI: 10.1021/Bi902010T  0.636
2009 Hopper ED, Pittman AM, Tucker CL, Campa MJ, Patz EF, Fitzgerald MC. Hydrogen/deuterium exchange- and protease digestion-based screening assay for protein-ligand binding detection. Analytical Chemistry. 81: 6860-7. PMID 20337380 DOI: 10.1021/Ac900854T  0.829
2009 Siburt CJ, Roulhac PL, Weaver KD, Noto JM, Mietzner TA, Cornelissen CN, Fitzgerald MC, Crumbliss AL. Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae. Metallomics : Integrated Biometal Science. 1: 249-55. PMID 20161024 DOI: 10.1039/B902860A  0.791
2009 Fitzgerald MC, West GM. Painting proteins with covalent labels: what's in the picture? Journal of the American Society For Mass Spectrometry. 20: 1193-206. PMID 19269190 DOI: 10.1016/J.Jasms.2009.02.006  0.742
2008 Hopper ED, Pittman AM, Fitzgerald MC, Tucker CL. In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. The Journal of Biological Chemistry. 283: 30493-502. PMID 18782763 DOI: 10.1074/Jbc.M803525200  0.8
2008 Hopper ED, Roulhac PL, Campa MJ, Patz EF, Fitzgerald MC. Throughput and efficiency of a mass spectrometry-based screening assay for protein-ligand binding detection. Journal of the American Society For Mass Spectrometry. 19: 1303-11. PMID 18653356 DOI: 10.1016/J.Jasms.2008.06.007  0.79
2008 Weaver KD, Heymann JJ, Mehta A, Roulhac PL, Anderson DS, Nowalk AJ, Adhikari P, Mietzner TA, Fitzgerald MC, Crumbliss AL. Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 887-98. PMID 18461372 DOI: 10.1007/S00775-008-0376-5  0.791
2008 West GM, Tang L, Fitzgerald MC. Thermodynamic analysis of protein stability and ligand binding using a chemical modification- and mass spectrometry-based strategy. Analytical Chemistry. 80: 4175-85. PMID 18457414 DOI: 10.1021/Ac702610A  0.776
2008 Roulhac PL, Weaver KD, Adhikari P, Anderson DS, DeArmond PD, Mietzner TA, Crumbliss AL, Fitzgerald MC. Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria. Biochemistry. 47: 4298-305. PMID 18338854 DOI: 10.1021/Bi701188X  0.798
2008 Fitzgerald MC, Tang L, Hopper ED. Chapter 6 Thermodynamic Analysis of Protein Folding and Ligand Binding by SUPREX Comprehensive Analytical Chemistry. 52: 127-149. DOI: 10.1016/S0166-526X(08)00206-7  0.828
2007 Tang L, Roulhac PL, Fitzgerald MC. H/D exchange and mass spectrometry-based method for biophysical analysis of multidomain proteins at the domain level. Analytical Chemistry. 79: 8728-39. PMID 17948968 DOI: 10.1021/Ac071380A  0.812
2007 Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, Fitzgerald MC. H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. Analytical Chemistry. 79: 5869-77. PMID 17580981 DOI: 10.1021/Ac0700777  0.829
2007 Williams JC, Roulhac PL, Roy AG, Vallee RB, Fitzgerald MC, Hendrickson WA. Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex. Proceedings of the National Academy of Sciences of the United States of America. 104: 10028-33. PMID 17551010 DOI: 10.1073/Pnas.0703614104  0.782
2007 Frankel BA, Tong Y, Bentley ML, Fitzgerald MC, McCafferty DG. Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. Biochemistry. 46: 7269-78. PMID 17518446 DOI: 10.1021/Bi700448E  0.534
2006 Dai SY, Fitzgerald MC. A mass spectrometry-based probe of equilibrium intermediates in protein-folding reactions. Biochemistry. 45: 12890-7. PMID 17042507 DOI: 10.1021/Bi061295H  0.459
2006 Yang X, Wang M, Fitzgerald MC. Direct analysis of backbone-backbone hydrogen bond formation in protein folding transition states. Journal of Molecular Biology. 363: 506-19. PMID 16963082 DOI: 10.1016/J.Jmb.2006.07.058  0.325
2006 Dai SY, Fitzgerald MC. Accuracy of SUPREX (stability of unpurified proteins from rates of H/D exchange) and MALDI mass spectrometry-derived protein unfolding free energies determined under non-EX2 exchange conditions. Journal of the American Society For Mass Spectrometry. 17: 1535-42. PMID 16872837 DOI: 10.1016/J.Jasms.2006.06.025  0.448
2006 Yang X, Fitzgerald MC. Total chemical synthesis of the B1 domain of protein L from Peptostreptococcus magnus. Bioorganic Chemistry. 34: 131-41. PMID 16690101 DOI: 10.1016/J.Bioorg.2006.02.001  0.413
2006 Wang M, Wales TE, Fitzgerald MC. Conserved thermodynamic contributions of backbone hydrogen bonds in a protein fold. Proceedings of the National Academy of Sciences of the United States of America. 103: 2600-4. PMID 16473949 DOI: 10.1073/Pnas.0508121103  0.647
2006 Cisneros GA, Wang M, Silinski P, Fitzgerald MC, Yang W. Theoretical and experimental determination on two substrates turned over by 4-oxalocrotonate tautomerase. The Journal of Physical Chemistry. A. 110: 700-8. PMID 16405343 DOI: 10.1021/Jp0543328  0.744
2005 Lin SM, Haney RP, Campa MJ, Fitzgerald MC, Patz EF. Characterising phase variations in MALDI-TOF data and correcting them by peak alignment. Cancer Informatics. 1: 32-40. PMID 19305630 DOI: 10.4137/Cin.S0  0.302
2005 Tong Y, Wuebbens MM, Rajagopalan KV, Fitzgerald MC. Thermodynamic analysis of subunit interactions in Escherichia coli molybdopterin synthase. Biochemistry. 44: 2595-601. PMID 15709772 DOI: 10.1021/Bi047762H  0.586
2005 Dai SY, Gardner MW, Fitzgerald MC. Protocol for the thermodynamic analysis of some proteins using an H/D exchange- and mass spectrometry-based technique. Analytical Chemistry. 77: 693-7. PMID 15649073 DOI: 10.1021/Ac048967Z  0.481
2004 Roulhac PL, Powell KD, Dhungana S, Weaver KD, Mietzner TA, Crumbliss AL, Fitzgerald MC. SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin. Biochemistry. 43: 15767-74. PMID 15595832 DOI: 10.1021/Bi0481848  0.802
2004 Howard BA, Zheng Z, Campa MJ, Wang MZ, Sharma A, Haura E, Herndon JE, Fitzgerald MC, Bepler G, Patz EF. Translating biomarkers into clinical practice: prognostic implications of cyclophilin A and macrophage migratory inhibitory factor identified from protein expression profiles in non-small cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 46: 313-23. PMID 15541816 DOI: 10.1016/J.Lungcan.2004.05.013  0.47
2004 Yang X, Wang M, Fitzgerald MC. Analysis of protein folding and function using backbone modified proteins. Bioorganic Chemistry. 32: 438-49. PMID 15381405 DOI: 10.1016/J.Bioorg.2004.06.011  0.449
2004 Wang MZ, Shetty JT, Howard BA, Campa MJ, Patz EF, Fitzgerald MC. Thermodynamic analysis of cyclosporin a binding to cyclophilin a in a lung tumor tissue lysate. Analytical Chemistry. 76: 4343-8. PMID 15283571 DOI: 10.1021/Ac049536J  0.574
2004 Cisneros GA, Wang M, Silinski P, Fitzgerald MC, Yang W. The protein backbone makes important contributions to 4-oxalocrotonate tautomerase enzyme catalysis: understanding from theory and experiment. Biochemistry. 43: 6885-92. PMID 15170325 DOI: 10.1021/Bi049943P  0.762
2004 Wales TE, Richardson JS, Fitzgerald MC. Facile chemical synthesis and equilibrium unfolding properties of CopG. Protein Science : a Publication of the Protein Society. 13: 1918-26. PMID 15169951 DOI: 10.1110/Ps.04671804  0.659
2004 Powell KD, Fitzgerald MC. High-throughput screening assay for the tunable selection of protein ligands. Journal of Combinatorial Chemistry. 6: 262-9. PMID 15002975 DOI: 10.1021/Cc034051E  0.655
2003 Ma L, Fitzgerald MC. A new H/D exchange- and mass spectrometry-based method for thermodynamic analysis of protein-DNA interactions. Chemistry & Biology. 10: 1205-13. PMID 14700628 DOI: 10.1016/J.Chembiol.2003.11.017  0.584
2003 Howard BA, Wang MZ, Campa MJ, Corro C, Fitzgerald MC, Patz EF. Identification and validation of a potential lung cancer serum biomarker detected by matrix-assisted laser desorption/ionization-time of flight spectra analysis. Proteomics. 3: 1720-4. PMID 12973732 DOI: 10.1002/Pmic.200300514  0.448
2003 Wang MZ, Howard B, Campa MJ, Patz EF, Fitzgerald MC. Analysis of human serum proteins by liquid phase isoelectric focusing and matrix-assisted laser desorption/ionization-mass spectrometry. Proteomics. 3: 1661-6. PMID 12973721 DOI: 10.1002/Pmic.200300513  0.501
2003 Silinski P, Fitzgerald MC. Comparative analysis of two different amide-to-ester bond mutations in the beta-sheet of 4-oxalocrotonate tautomerase. Biochemistry. 42: 6620-30. PMID 12767246 DOI: 10.1021/Bi020700B  0.756
2003 Powell KD, Fitzgerald MC. Accuracy and precision of a new H/D exchange- and mass spectrometry-based technique for measuring the thermodynamic properties of protein-peptide complexes. Biochemistry. 42: 4962-70. PMID 12718538 DOI: 10.1021/Bi034096W  0.629
2003 Campa MJ, Wang MZ, Howard B, Fitzgerald MC, Patz EF. Protein expression profiling identifies macrophage migration inhibitory factor and cyclophilin a as potential molecular targets in non-small cell lung cancer. Cancer Research. 63: 1652-6. PMID 12670919  0.422
2003 Powell KD, Ghaemmaghami S, Wang MZ, Ma L, Oas aTG, Fitzgerald MC. A General Mass Spectrometry-Based Assay for the Quantitation of Protein−Ligand Binding Interactions in Solution [J. Am. Chem. Soc. 2002, 124, 10256−10257]. Journal of the American Chemical Society. 125: 4398-4398. DOI: 10.1021/Ja0251266  0.592
2003 Powell KD, Wang MZ, Silinski P, Ma L, Wales TE, Dai SY, Warner AH, Yang X, Fitzgerald MC. The accuracy and precision of a new H/D exchange- and mass spectrometry-based technique for measuring the thermodynamic stability of proteins Analytica Chimica Acta. 496: 225-232. DOI: 10.1016/S0003-2670(03)01002-X  0.809
2002 Powell KD, Ghaemmaghami S, Wang MZ, Ma L, Oas TG, Fitzgerald MC. A general mass spectrometry-based assay for the quantitation of protein-ligand binding interactions in solution. Journal of the American Chemical Society. 124: 10256-7. PMID 12197709 DOI: 10.1021/Ja026574G  0.766
2002 Silinski P, Fitzgerald MC. A stable dimer in the pH-induced equilibrium unfolding of the homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT). Biochemistry. 41: 4480-91. PMID 11914096 DOI: 10.1021/Bi011872W  0.755
2002 Powell KD, Wales TE, Fitzgerald MC. Thermodynamic stability measurements on multimeric proteins using a new H/D exchange- and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry-based method. Protein Science : a Publication of the Protein Society. 11: 841-51. PMID 11910027 DOI: 10.1110/Ps.3820102  0.775
2002 Powell KD, Fitzgerald MC. Quantitative determination of protein-peptide binding constants using a new, MALDI- and H/D-exchange based technique Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 445-446.  0.57
2002 Ma L, Powell KD, Fitzgerald MC. A new H/D exchange- and MALDI-based assay for the quantitative analysis of protein-DNA interactions in solution Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 471-472.  0.529
2002 Fitzgerald MC, Powell KD, Wang MZ, Ma L, Ghaemmaghami S, Oas TG. A general mass spectrometry-based method for the quantitation of protein-ligand binding interactions in solution Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 395-396.  0.656
2002 Wang MZ, Campa M, Howard BA, Patz EF, Fitzgerald MC. A fractionation protocol to reduce signal suppression effects in the MALDI analysis of blood proteins Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 587-588.  0.413
2001 Wales TE, Fitzgerald MC. The energetic contribution of backbone--backbone hydrogen bonds to the thermodynamic stability of a hyperstable P22 Arc repressor mutant. Journal of the American Chemical Society. 123: 7709-10. PMID 11480998 DOI: 10.1021/Ja010775N  0.606
2001 Powell KD, Fitzgerald MC. Measurements of protein stability by H/D exchange and matrix-assisted laser desorption/ionization mass spectrometry using picomoles of material. Analytical Chemistry. 73: 3300-4. PMID 11476229 DOI: 10.1021/Ac0100805  0.634
2001 Moss JA, Silinski P, Fitzgerald MC. Mapping tertiary interactions in protein folding reactions: a novel mass spectrometry- and chemical synthesis-based approach. Fresenius' Journal of Analytical Chemistry. 369: 252-7. PMID 11293701 DOI: 10.1007/S002160000644  0.792
2001 Silinski P, Allingham MJ, Fitzgerald MC. Guanidine-induced equilibrium unfolding of a homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT). Biochemistry. 40: 4493-502. PMID 11284706 DOI: 10.1021/Bi002752B  0.757
2001 Wang MZ, Fitzgerald MC. A solid sample preparation method that reduces signal suppression effects in the MALDI analysis of peptides. Analytical Chemistry. 73: 625-31. PMID 11217772 DOI: 10.1021/Ac0009090  0.44
2000 Ghaemmaghami S, Fitzgerald MC, Oas TG. A quantitative, high-throughput screen for protein stability. Proceedings of the National Academy of Sciences of the United States of America. 97: 8296-301. PMID 10890887 DOI: 10.1073/Pnas.140111397  0.484
2000 Nakhle BM, Silinski P, Fitzgerald MC. Identification of an essential backbone amide bond in the folding and stability of a multimeric enzyme Journal of the American Chemical Society. 122: X. DOI: 10.1021/Ja0006090  0.771
2000 Nakhle BM, Silinski P, Fitzgerald MC. Identification of an essential backbone amide bond in the folding and stability of a multimeric enzyme Journal of the American Chemical Society. 122: X. DOI: 10.1021/ja0006090  0.742
1998 Beeston RF, Aldridge WS, Treadway JA, Fitzgerald MC, DeGraff BA, Stitzel SE. Synthesis, Characterization, and Photochemical/Photophysical Properties of Ruthenium(II) Complexes with Hexadentate Bipyridine and Phenanthroline Ligands. Inorganic Chemistry. 37: 4368-4379. PMID 11670574 DOI: 10.1021/Ic971322F  0.767
1998 Winston RL, Fitzgerald MC. Concentration and desalting of protein samples for mass spectrometry analysis. Analytical Biochemistry. 262: 83-5. PMID 9735152 DOI: 10.1006/Abio.1998.2754  0.357
1998 Stamps SL, Fitzgerald MC, Whitman CP. Characterization of the role of the amino-terminal proline in the enzymatic activity catalyzed by macrophage migration inhibitory factor. Biochemistry. 37: 10195-202. PMID 9665726 DOI: 10.1021/Bi9806955  0.322
1997 Winston RL, Fitzgerald MC. Mass spectrometry as a readout of protein structure and function. Mass Spectrometry Reviews. 16: 165-79. PMID 9449832 DOI: 10.1002/(Sici)1098-2787(1997)16:4<165::Aid-Mas1>3.0.Co;2-F  0.445
1997 Fitzgerald MC, Laco GS, Elder JH, Kent SB. A continuous fluorometric assay for the feline immunodeficiency virus protease. Analytical Biochemistry. 254: 226-30. PMID 9417781 DOI: 10.1006/Abio.1997.2407  0.508
1997 Johnson WH, Czerwinski RM, Fitzgerald MC, Whitman CP. Inactivation of 4-oxalocrotonate tautomerase by 2-oxo-3-pentynoate. Biochemistry. 36: 15724-32. PMID 9398301 DOI: 10.1021/Bi971608W  0.322
1997 Muir TW, Dawson PE, Fitzgerald MC, Kent SB. Protein signature analysis: a practical new approach for studying structure-activity relationships in peptides and proteins. Methods in Enzymology. 289: 545-64. PMID 9353737 DOI: 10.1016/S0076-6879(97)89063-5  0.76
1997 Laco GS, Fitzgerald MC, Morris GM, Olson AJ, Kent SB, Elder JH. Molecular analysis of the feline immunodeficiency virus protease: generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases. Journal of Virology. 71: 5505-11. PMID 9188624 DOI: 10.1128/Jvi.71.7.5505-5511.1997  0.523
1997 Dawson PE, Fitzgerald MC, Muir TW, Kent SBH. Methods for the chemical synthesis and readout of self-encoded arrays of polypeptide analogues Journal of the American Chemical Society. 119: 7917-7927. DOI: 10.1021/Ja963122T  0.639
1996 Muir TW, Dawson PE, Fitzgerald MC, Kent SB. Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis. Chemistry & Biology. 3: 817-25. PMID 8939700 DOI: 10.1016/S1074-5521(96)90067-8  0.778
1996 Fitzgerald MC, Chernushevich I, Standing KG, Whitman CP, Kent SB. Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 93: 6851-6. PMID 8692908 DOI: 10.1073/Pnas.93.14.6851  0.551
1996 Fitzgerald MC, Harris K, Shevlin CG, Siuzdak G. Direct characterization of solid phase resin-bound molecules by mass spectrometry Bioorganic and Medicinal Chemistry Letters. 6: 979-982. DOI: 10.1016/0960-894X(96)00152-7  0.305
1995 Fitzgerald MC, Smith LM. Mass spectrometry of nucleic acids: the promise of matrix-assisted laser desorption-ionization (MALDI) mass spectrometry. Annual Review of Biophysics and Biomolecular Structure. 24: 117-40. PMID 7663111 DOI: 10.1146/Annurev.Bb.24.060195.001001  0.487
1995 Zhu L, Parr GR, Fitzgerald MC, Nelson CM, Smith LM. Oligodeoxynucleotide fragmentation in MALDI/TOF mass spectrometry using 355-nm radiation Journal of the American Chemical Society. 117: 6048-6056. DOI: 10.1021/Ja00127A018  0.47
1993 Fitzgerald MC, Parr GR, Smith LM. Basic matrices for the matrix-assisted laser desorption/ionization mass spectrometry of proteins and oligonucleotides. Analytical Chemistry. 65: 3204-11. PMID 8291672 DOI: 10.1021/Ac00070A007  0.533
1993 Fitzgerald MC, Zhu L, Smith LM. The analysis of mock DNA sequencing reactions using matrix-assisted laser desorption/ionization mass spectrometry Rapid Communications in Mass Spectrometry. 7: 895-897. DOI: 10.1002/Rcm.1290071008  0.476
1992 Fitzgerald MC, Skowron P, Van Etten JL, Smith LM, Mead DA. Rapid shotgun cloning utilizing the two base recognition endonuclease CviJI. Nucleic Acids Research. 20: 3753-62. PMID 1322530 DOI: 10.1093/Nar/20.14.3753  0.463
1992 Parr GR, Fitzgerald MC, Smith LM. Matrix-assisted laser desorption/ionization mass spectrometry of synthetic oligodeoxyribonucleotides Rapid Communications in Mass Spectrometry. 6: 369-372. DOI: 10.1002/Rcm.1290060603  0.489
1989 Beeston RF, Larson SL, Fitzgerald MC. Ground- and excited-state properties of a photostable hemicage ruthenium(II) polypyridine complex Inorganic Chemistry. 28: 4187-4189. DOI: 10.1021/Ic00322A003  0.748
Show low-probability matches.