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Heiko Wurdak - Publications

Affiliations: 
University of Leeds, UK 
Area:
Stem cell and tumor biology
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Andreou T, Williams J, Brownlie RJ, Salmond RJ, Watson E, Shaw G, Melcher A, Wurdak H, Short SC, Lorger M. Hematopoietic stem cell gene therapy targeting TGFβ enhances the efficacy of irradiation therapy in a preclinical glioblastoma model. Journal For Immunotherapy of Cancer. 9. PMID 33707311 DOI: 10.1136/jitc-2020-001143  0.318
2020 Alshawli AS, Wurdak H, Wood IC, Ladbury JE. Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes. Molecular Genetics & Genomic Medicine. e1429. PMID 32720471 DOI: 10.1002/Mgg3.1429  0.341
2019 Close HJ, Stead LF, Nsengimana J, Reilly KA, Droop A, Wurdak H, Mathew RK, Corns R, Newton-Bishop J, Melcher AA, Short SC, Cook GP, Wilson EB. Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma. Clinical and Experimental Immunology. PMID 31784984 DOI: 10.1111/Cei.13403  0.441
2019 da Silva B, Irving BK, Polson ES, Droop A, Griffiths HBS, Mathew RK, Stead LF, Marrison J, Williams C, Williams J, Short SC, Scarcia M, O'Toole PJ, Allison SJ, Mavria G, ... Wurdak H, et al. Chemically-induced neurite-like outgrowth reveals multicellular network function in patient-derived glioblastoma cells. Journal of Cell Science. PMID 31515278 DOI: 10.1242/jcs.228452  0.357
2019 Lucki NC, Villa GR, Vergani N, Bollong MJ, Beyer BA, Lee JW, Anglin JL, Spangenberg SH, Chin EN, Sharma A, Johnson K, Sander PN, Gordon P, Skirboll SL, Wurdak H, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30846550 DOI: 10.1073/Pnas.1816626116  0.736
2018 Haynes HR, Scott HL, Killick-Cole CL, Shaw G, Brend T, Hares KM, Redondo J, Kemp KC, Ballesteros LS, Herman A, Cordero-Llana O, Singleton WG, Mills F, Batstone T, Bulstrode H, ... ... Wurdak H, et al. shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth. The Journal of Pathology. PMID 30565681 DOI: 10.1002/Path.5201  0.43
2018 Polson ES, Kuchler VB, Abbosh C, Ross EM, Mathew RK, Beard HA, da Silva B, Holding AN, Ballereau S, Chuntharpursat-Bon E, Williams J, Griffiths HBS, Shao H, Patel A, Davies AJ, ... ... Wurdak H, et al. KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice. Science Translational Medicine. 10. PMID 30111643 DOI: 10.1126/Scitranslmed.Aar2718  0.544
2018 da Silva B, Mathew RK, Polson ES, Williams J, Wurdak H. Spontaneous Glioblastoma Spheroid Infiltration of Early-Stage Cerebral Organoids Models Brain Tumor Invasion. Slas Discovery : Advancing Life Sciences R & D. 2472555218764623. PMID 29543559 DOI: 10.1177/2472555218764623  0.322
2018 Samson A, Scott KJ, Taggart D, West EJ, Wilson E, Nuovo GJ, Thomson S, Corns R, Mathew RK, Fuller MJ, Kottke TJ, Thompson JM, Ilett EJ, Cockle JV, van Hille P, ... ... Wurdak H, et al. Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine. 10. PMID 29298869 DOI: 10.1126/Scitranslmed.Aam7577  0.337
2017 King HO, Brend T, Payne HL, Wright A, Ward TA, Patel K, Egnuni T, Stead LF, Patel A, Wurdak H, Short SC. RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells. Stem Cell Reports. 8: 125-139. PMID 28076755 DOI: 10.1016/J.Stemcr.2016.12.005  0.433
2017 Andreou T, Rippaus N, Taggart D, Williams J, Wronski K, Short S, Wurdak H, Lorger M. Pp27. Establishment Of A Haematopoietic Stem-Cell Based Therapy For Brain Tumours In Pre-Clinical Mouse Models Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Now293.026  0.441
2016 Rippaus N, Taggart D, Williams J, Andreou T, Wurdak H, Wronski K, Lorger M. Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases. Oncotarget. PMID 27203741 DOI: 10.18632/Oncotarget.9445  0.344
2014 Hayes J, Thygesen H, Droop A, Boissinot M, Bellamy C, Hughes T, Westhead D, Shaw L, Wurdak H, Lawler S, Short S. BI-11PROGNOSTIC microRNAS IN MALIGNANT GLIOMA Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou239.11  0.303
2012 Wurdak H. Exploring the cancer stem cell phenotype with high-throughput screening applications. Future Medicinal Chemistry. 4: 1229-41. PMID 22800368 DOI: 10.4155/Fmc.12.73  0.478
2011 Lyssiotis CA, Lairson LL, Boitano AE, Wurdak H, Zhu S, Schultz PG. Chemical control of stem cell fate and developmental potential. Angewandte Chemie (International Ed. in English). 50: 200-42. PMID 21184400 DOI: 10.1002/Anie.201004284  0.78
2010 Zhu S, Wurdak H, Schultz PG. Directed embryonic stem cell differentiation with small molecules. Future Medicinal Chemistry. 2: 965-73. PMID 21426114 DOI: 10.4155/Fmc.10.190  0.729
2010 Wurdak H, Zhu S, Min KH, Aimone L, Lairson LL, Watson J, Chopiuk G, Demas J, Charette B, Halder R, Weerapana E, Cravatt BF, Cline HT, Peters EC, Zhang J, et al. A small molecule accelerates neuronal differentiation in the adult rat. Proceedings of the National Academy of Sciences of the United States of America. 107: 16542-7. PMID 20823227 DOI: 10.1073/Pnas.1010300107  0.673
2010 Wurdak H, Zhu S, Romero A, Lorger M, Watson J, Chiang CY, Zhang J, Natu VS, Lairson LL, Walker JR, Trussell CM, Harsh GR, Vogel H, Felding-Habermann B, Orth AP, et al. An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation. Cell Stem Cell. 6: 37-47. PMID 20085741 DOI: 10.1016/J.Stem.2009.11.002  0.773
2010 Lyssiotis CA, Lairson LL, Boitano AE, Wurdak H, Zhu S, Schultz PG. Chemische Kontrolle des Schicksals und Entwicklungspotenzials von Stammzellen Angewandte Chemie. 123: 210-256. DOI: 10.1002/Ange.201004284  0.673
2009 Zhu S, Wurdak H, Wang Y, Galkin A, Tao H, Li J, Lyssiotis CA, Yan F, Tu BP, Miraglia L, Walker J, Sun F, Orth A, Schultz PG, Wu X. A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 17025-30. PMID 19805117 DOI: 10.1073/Pnas.0909292106  0.723
2009 Zhu S, Wurdak H, Wang J, Lyssiotis CA, Peters EC, Cho CY, Wu X, Schultz PG. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell. 4: 416-26. PMID 19427291 DOI: 10.1016/J.Stem.2009.04.001  0.655
2009 Alves J, Wurdak H, Garay-Malpartida HM, Harris JL, Occhiucci JM, Belizário JE, Li J. TAF15 and the leukemia-associated fusion protein TAF15-CIZ/NMP4 are cleaved by caspases-3 and -7. Biochemical and Biophysical Research Communications. 384: 495-500. PMID 19426707 DOI: 10.1016/J.Bbrc.2009.05.009  0.352
2008 Falk S, Wurdak H, Ittner LM, Ille F, Sumara G, Schmid MT, Draganova K, Lang KS, Paratore C, Leveen P, Suter U, Karlsson S, Born W, Ricci R, Götz M, et al. Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion. Cell Stem Cell. 2: 472-83. PMID 18462697 DOI: 10.1016/J.Stem.2008.03.006  0.431
2005 Ittner LM, Wurdak H, Schwerdtfeger K, Kunz T, Ille F, Leveen P, Hjalt TA, Suter U, Karlsson S, Hafezi F, Born W, Sommer L. Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells. Journal of Biology. 4: 11. PMID 16403239 DOI: 10.1186/Jbiol29  0.339
2005 Kléber M, Lee HY, Wurdak H, Buchstaller J, Riccomagno MM, Ittner LM, Suter U, Epstein DJ, Sommer L. Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling. The Journal of Cell Biology. 169: 309-20. PMID 15837799 DOI: 10.1083/Jcb.200411095  0.379
2005 Wurdak H, Ittner LM, Lang KS, Leveen P, Suter U, Fischer JA, Karlsson S, Born W, Sommer L. Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes & Development. 19: 530-5. PMID 15741317 DOI: 10.1101/Gad.317405  0.317
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