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Claudio A. Zambaldo - Publications

Affiliations: 
F.Hoffmann La Roche 
Area:
Synthetic Chemistry, Chemical Biology
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shalhout SZ, Yang PY, Grzelak EM, Nutsch K, Shao S, Zambaldo C, Iaconelli J, Ibrahim L, Stanton C, Chadwick SR, Chen E, DeRan M, Li S, Hull M, Wu X, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nature Chemical Biology. PMID 33723431 DOI: 10.1038/s41589-021-00755-0  0.768
2020 Zambaldo C, Koh M, Nasertorabi F, Han GW, Chatterjee A, Stevens RC, Schultz PG. An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli. Bioorganic & Medicinal Chemistry. 28: 115662. PMID 33069069 DOI: 10.1016/J.Bmc.2020.115662  0.782
2020 Zambaldo C, Vinogradova EV, Qi X, Iaconelli J, Suciu RM, Koh M, Senkane K, Chadwick SR, Sanchez BB, Chen JS, Chatterjee AK, Liu P, Schultz PG, Cravatt BF, Bollong MJ. 2-Sulfonyl pyridines as tunable, cysteine-reactive electrophiles. Journal of the American Chemical Society. PMID 32302104 DOI: 10.1021/Jacs.0C02721  0.794
2019 Zambaldo C, Geigle SN, Satz AL. High-Throughput Solid-Phase Building Block Synthesis for DNA-Encoded Libraries. Organic Letters. PMID 31747291 DOI: 10.1021/Acs.Orglett.9B03553  0.314
2018 Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. PMID 30323285 DOI: 10.1038/S41586-018-0622-0  0.758
2018 Supekova L, Zambaldo C, Choi S, Lim R, Luo X, Kazane SA, Young TS, Schultz PG. The genetic incorporation of p-azidomethyl-l-phenylalanine into proteins in yeast. Bioorganic & Medicinal Chemistry Letters. PMID 29625824 DOI: 10.1016/J.Bmcl.2018.03.055  0.759
2017 Zambaldo C, Luo X, Mehta AP, Schultz PG. Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids. Journal of the American Chemical Society. PMID 28809560 DOI: 10.1021/Jacs.7B04159  0.793
2017 Saarbach J, Masi D, Zambaldo C, Winssinger N. Facile access to modified and functionalized PNAs through Ugi-based solid phase oligomerization. Bioorganic & Medicinal Chemistry. PMID 28624242 DOI: 10.1016/J.Bmc.2017.05.064  0.698
2017 Luo X, Fu G, Wang RE, Zhu X, Zambaldo C, Liu R, Liu T, Lyu X, Du J, Xuan W, Yao A, Reed SA, Kang M, Zhang Y, Guo H, et al. Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria. Nature Chemical Biology. PMID 28604693 DOI: 10.1038/Nchembio.2405  0.67
2017 Bollong MJ, Yang B, Vergani N, Beyer BA, Chin EN, Zambaldo C, Wang D, Chatterjee AK, Lairson LL, Schultz PG. Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 114: 4679-4684. PMID 28416697 DOI: 10.1073/Pnas.1702750114  0.763
2016 Yu S, Pearson AD, Lim RK, Rodgers DT, Li S, Parker HB, Weglarz M, Hampton EN, Bollong MJ, Shen J, Zambaldo C, Wang D, Woods AK, Wright TM, Schultz PG, et al. Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody-drug conjugate. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27731313 DOI: 10.1038/Mt.2016.175  0.715
2016 Luo X, Zambaldo C, Liu T, Zhang Y, Xuan W, Wang C, Reed SA, Yang PY, Wang RE, Javahishvili T, Schultz PG, Young TS. Recombinant thiopeptides containing noncanonical amino acids. Proceedings of the National Academy of Sciences of the United States of America. 113: 3615-20. PMID 26976568 DOI: 10.1073/Pnas.1602733113  0.748
2016 Zambaldo C, Daguer J, Saarbach J, Barluenga S, Winssinger N. Screening for covalent inhibitors using DNA-display of small molecule libraries functionalized with cysteine reactive moieties Medchemcomm. 7: 1340-1351. DOI: 10.1039/C6Md00242K  0.674
2015 Daguer JP, Zambaldo C, Ciobanu M, Morieux P, Barluenga S, Winssinger N. DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules. Chemical Science. 6: 739-744. PMID 30154995 DOI: 10.1039/C4Sc01654H  0.708
2015 Barluenga S, Zambaldo C, Ioannidou HA, Ciobanu M, Morieux P, Daguer JP, Winssinger N. Novel PTP1B inhibitors identified by DNA display of fragment pairs. Bioorganic & Medicinal Chemistry Letters. PMID 26691757 DOI: 10.1016/J.Bmcl.2015.11.102  0.757
2015 Daguer JP, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules. Angewandte Chemie (International Ed. in English). 54: 6057-61. PMID 25772490 DOI: 10.1002/Anie.201412276  0.686
2015 Zambaldo C, Barluenga S, Winssinger N. PNA-encoded chemical libraries. Current Opinion in Chemical Biology. 26: 8-15. PMID 25621730 DOI: 10.1016/J.Cbpa.2015.01.005  0.703
2015 Daguer JP, Zambaldo C, Ciobanu M, Morieux P, Barluenga S, Winssinger N. DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules Chemical Science. 6: 739-744. DOI: 10.1039/c4sc01654h  0.65
2015 Daguer J, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Identifizierung von niedermolekularen kovalenten Bromodomäne-Bindern aus einer DNA-kodierten Bibliothek Angewandte Chemie. 127: 6155-6159. DOI: 10.1002/Ange.201412276  0.615
2013 Zambaldo C, Sadhu KK, Karthikeyan G, Barluenga S, Daguer JP, Winssinger N. Selective affinity-based probe for oncogenic kinases suitable for live cell imaging Chemical Science. 4: 2088-2092. DOI: 10.1039/C3Sc21856B  0.776
2012 Chouikhi D, Ciobanu M, Zambaldo C, Duplan V, Barluenga S, Winssinger N. Expanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12698-704. PMID 22915361 DOI: 10.1002/Chem.201201337  0.704
2012 Karthikeyan G, Zambaldo C, Barluenga S, Zoete V, Karplus M, Winssinger N. Asymmetric synthesis of pochonin E and F, revision of their proposed structure, and their conversion to potent Hsp90 inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8978-86. PMID 22696415 DOI: 10.1002/Chem.201200546  0.71
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