Diana Imhof - Publications

Affiliations: 
2004-2005 Ohio State University, Columbus, Columbus, OH 

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pepanian A, Binbay FA, Pei D, Imhof D. Design, synthesis, and analysis of macrobicyclic peptides for targeting the Gαi protein. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3565. PMID 38232955 DOI: 10.1002/psc.3565  0.547
2023 Pepanian A, Binbay FA, Roy S, Nubbemeyer B, Koley A, Rhodes CA, Ammer H, Pei D, Ghosh P, Imhof D. Bicyclic Peptide Library Screening for the Identification of Gαi Protein Modulators. Journal of Medicinal Chemistry. PMID 37587416 DOI: 10.1021/acs.jmedchem.3c00873  0.54
2022 Nubbemeyer B, Paul George AA, Kühl T, Pepanian A, Beck MS, Maghraby R, Shetab Boushehri M, Muehlhaupt M, Pfeil EM, Annala SK, Ammer H, Imhof D, Pei D. Targeting Gαi/s Proteins with Peptidyl Nucleotide Exchange Modulators. Acs Chemical Biology. PMID 35042325 DOI: 10.1021/acschembio.1c00929  0.524
2020 Schmitz T, Pengelley S, Belau E, Suckau D, Imhof D. LC-Trapped Ion Mobility Spectrometry-TOF MS Differentiation of 2- and 3-Disulfide-Bonded Isomers of the μ-Conotoxin PIIIA. Analytical Chemistry. 92: 10920-10924. PMID 32806900 DOI: 10.1021/Acs.Analchem.0C02151  0.319
2020 Imhof D, Hopp MT, Alhanafi N, Paul George AA, Hamedani NS, Biswas A, Oldenburg J, Pötzsch B. Molecular insights and functional consequences of the interaction of heme with activated protein C. Antioxidants & Redox Signaling. PMID 32705892 DOI: 10.1089/Ars.2019.7992  0.316
2020 Bäuml CA, Paul George AA, Schmitz T, Sommerfeld P, Pietsch M, Podsiadlowski L, Steinmetzer T, Biswas A, Imhof D. Distinct 3-disulfide-bonded isomers of tridegin differentially inhibit coagulation factor XIIIa: The influence of structural stability on bioactivity. European Journal of Medicinal Chemistry. 201: 112474. PMID 32698061 DOI: 10.1016/J.Ejmech.2020.112474  0.414
2020 Hopp MT, Schmalohr BF, Kühl T, Detzel MS, Wißbrock A, Imhof D. Heme Determination and Quantification Methods and Their Suitability for Practical Applications and Everyday Use. Analytical Chemistry. PMID 32490668 DOI: 10.1021/Acs.Analchem.0C00415  0.3
2020 Schmitz T, Bäuml CA, Imhof D. Inhibitors of blood coagulation factor XIIIa. Analytical Biochemistry. 113708. PMID 32335064 DOI: 10.1016/J.Ab.2020.113708  0.319
2020 Syllwasschy BF, Beck MS, Družeta I, Hopp MT, Ramoji A, Neugebauer U, Nozinovic S, Menche D, Willbold D, Ohlenschläger O, Kühl T, Imhof D. High-affinity binding and catalytic activity of His/Tyr-based sequences: Extending heme-regulatory motifs beyond CP. Biochimica Et Biophysica Acta. General Subjects. 129603. PMID 32234408 DOI: 10.1016/J.Bbagen.2020.129603  0.463
2020 Paul George AA, Lacerda M, Syllwasschy BF, Hopp MT, Wißbrock A, Imhof D. HeMoQuest: a webserver for qualitative prediction of transient heme binding to protein motifs. Bmc Bioinformatics. 21: 124. PMID 32216745 DOI: 10.1186/S12859-020-3420-2  0.357
2019 Singh S, Dodt J, Volkers P, Hethershaw E, Philippou H, Ivaskevicius V, Imhof D, Oldenburg J, Biswas A. Structure functional insights into calcium binding during the activation of coagulation factor XIII A. Scientific Reports. 9: 11324. PMID 31383913 DOI: 10.1038/S41598-019-47815-Z  0.305
2019 Kumar A, Bellstedt P, Wiedemann C, Wißbrock A, Imhof D, Ramachandran R, Ohlenschläger O. NMR experiments on the transient interaction of the intrinsically disordered N-terminal peptide of cystathionine-β-synthase with heme. Journal of Magnetic Resonance (San Diego, Calif. : 1997). PMID 31345774 DOI: 10.1016/J.Jmr.2019.07.048  0.36
2019 Paul George AA, Heimer P, Leipold E, Schmitz T, Kaufmann D, Tietze D, Heinemann SH, Imhof D. Effect of Conformational Diversity on the Bioactivity of µ-Conotoxin PIIIA Disulfide Isomers. Marine Drugs. 17. PMID 31269696 DOI: 10.3390/Md17070390  0.354
2019 Bäuml CA, Schmitz T, Paul George AA, Sudarsanam M, Hardes K, Steinmetzer T, Holle LA, Wolberg AS, Pötzsch B, Oldenburg J, Biswas A, Imhof D. COAGULATION FACTOR XIIIA-INHIBITOR TRIDEGIN: ON THE ROLE OF DISULFIDE BONDS FOR FOLDING, STABILITY, AND FUNCTION. Journal of Medicinal Chemistry. PMID 30852892 DOI: 10.1021/Acs.Jmedchem.8B01982  0.388
2019 Wißbrock A, Paul George AA, Brewitz HH, Kühl T, Imhof D. The Molecular Basis of Transient Heme-Protein Interactions: Analysis, Concept and Implementation. Bioscience Reports. PMID 30622148 DOI: 10.1042/Bsr20181940  0.391
2018 Paul George AA, Heimer P, Maaß A, Hamaekers J, Hofmann-Apitius M, Biswas A, Imhof D. Insights into the Folding of Disulfide-Rich μ-Conotoxins. Acs Omega. 3: 12330-12340. PMID 30411002 DOI: 10.1021/acsomega.8b01465  0.302
2018 Heimer P, Schmitz T, Bäuml CA, Imhof D. Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities. Journal of Visualized Experiments : Jove. PMID 30346393 DOI: 10.3791/58368  0.419
2018 Imhof D, Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM. Deciphering specificity determinants for FR900359-derived Gαq inhibitors based on computational and structure-activity studies. Chemmedchem. PMID 29873888 DOI: 10.1002/Cmdc.201800304  0.4
2018 Oppermann S, Oppermann C, Böhm M, Kühl T, Imhof D, Kragl U. Quantification of amino acids and peptides in an ionic liquid based aqueous two-phase system by LC-MS analysis. Amb Express. 8: 66. PMID 29696483 DOI: 10.1186/S13568-018-0596-1  0.364
2018 Kumar A, Wißbrock A, Goradia N, Bellstedt P, Ramachandran R, Imhof D, Ohlenschläger O. Heme interaction of the intrinsically disordered N-terminal peptide segment of human cystathionine-β-synthase. Scientific Reports. 8: 2474. PMID 29410458 DOI: 10.1038/S41598-018-20841-Z  0.381
2018 Heimer P, Tietze AA, Bäuml CA, Resemann A, Mayer FJ, Suckau D, Ohlenschläger O, Tietze D, Imhof D. Conformational μ-Conotoxin PIIIA Isomers Revisited: Impact of Cysteine Pairing on Disulfide-Bond Assignment and Structure Elucidation. Analytical Chemistry. PMID 29397705 DOI: 10.1021/Acs.Analchem.7B04854  0.395
2017 Tietze D, Sartorius J, Koley Seth B, Herr K, Heimer P, Imhof D, Mollenhauer D, Buntkowsky G. New insights into the mechanism of nickel superoxide degradation from studies of model peptides. Scientific Reports. 7: 17194. PMID 29222438 DOI: 10.1038/S41598-017-17446-3  0.375
2016 Brewitz HH, Hagelueken G, Imhof D. Structural and functional diversity of transient heme binding to bacterial proteins. Biochimica Et Biophysica Acta. PMID 28012743 DOI: 10.1016/J.Bbagen.2016.12.021  0.303
2016 Wißbrock A, Kühl T, Silbermann K, Becker AJ, Ohlenschläger O, Imhof D. Synthesis and Evaluation of Amyloid β Derived and Amyloid β Independent Enhancers of the Peroxidase-like Activity of Heme. Journal of Medicinal Chemistry. PMID 27976903 DOI: 10.1021/Acs.Jmedchem.6B01432  0.395
2016 Blaurock N, Schmerler D, Hünniger K, Kurzai O, Ludewig K, Baier M, Brunkhorst FM, Imhof D, Kiehntopf M. C-Terminal Alpha-1 Antitrypsin Peptide: A New Sepsis Biomarker with Immunomodulatory Function. Mediators of Inflammation. 2016: 6129437. PMID 27382189 DOI: 10.1155/2016/6129437  0.333
2016 Tietze D, Leipold E, Heimer P, Böhm M, Winschel W, Imhof D, Heinemann SH, Tietze AA. Molecular interaction of δ-conopeptide EVIA with voltage-gated Na(+) channels. Biochimica Et Biophysica Acta. PMID 27316322 DOI: 10.1016/J.Bbagen.2016.06.013  0.321
2016 Brewitz HH, Goradia N, Schubert E, Galler K, Kühl T, Syllwasschy B, Popp J, Neugebauer U, Hagelueken G, Schiemann O, Ohlenschläger O, Imhof D. Heme interacts with histidine- and tyrosine-based protein motifs and inhibits enzymatic activity of chloramphenicol acetyltransferase from Escherichiacoli. Biochimica Et Biophysica Acta. PMID 27015758 DOI: 10.1016/J.Bbagen.2016.03.027  0.427
2015 Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, ... ... Imhof D, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156. PMID 26658454 DOI: 10.1038/Ncomms10156  0.317
2015 Brewitz HH, Kühl T, Goradia N, Galler K, Popp J, Neugebauer U, Ohlenschläger O, Imhof D. Role of the Chemical Environment beyond the Coordination Site: Structural Insight into Fe(III) Protoporphyrin Binding to Cysteine-Based Heme-Regulatory Protein Motifs. Chembiochem : a European Journal of Chemical Biology. 16: 2216-24. PMID 26260099 DOI: 10.1002/Cbic.201500331  0.418
2015 Schubert E, Florin N, Duthie F, Henning Brewitz H, Kühl T, Imhof D, Hagelueken G, Schiemann O. Spectroscopic studies on peptides and proteins with cysteine-containing heme regulatory motifs (HRM). Journal of Inorganic Biochemistry. 148: 49-56. PMID 26050879 DOI: 10.1016/J.Jinorgbio.2015.05.008  0.428
2015 Chen M, Heimer P, Imhof D. Synthetic strategies for polypeptides and proteins by chemical ligation. Amino Acids. 47: 1283-99. PMID 25894893 DOI: 10.1007/S00726-015-1982-5  0.413
2014 Böhm M, Bäuml CA, Hardes K, Steinmetzer T, Roeser D, Schaub Y, Than ME, Biswas A, Imhof D. Novel insights into structure and function of factor XIIIa-inhibitor tridegin. Journal of Medicinal Chemistry. 57: 10355-65. PMID 25415134 DOI: 10.1021/Jm501058G  0.44
2014 Heimer P, Tietze AA, Böhm M, Giernoth R, Kuchenbuch A, Stark A, Leipold E, Heinemann SH, Kandt C, Imhof D. Application of room-temperature aprotic and protic ionic liquids for oxidative folding of cysteine-rich peptides. Chembiochem : a European Journal of Chemical Biology. 15: 2754-65. PMID 25376613 DOI: 10.1002/Cbic.201402356  0.383
2014 Schmitz AL, Schrage R, Gaffal E, Charpentier TH, Wiest J, Hiltensperger G, Morschel J, Hennen S, Häußler D, Horn V, Wenzel D, Grundmann M, Büllesbach KM, Schröder R, Brewitz HH, ... ... Imhof D, et al. A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation. Chemistry & Biology. 21: 890-902. PMID 25036778 DOI: 10.1016/J.Chembiol.2014.06.003  0.333
2014 Hennig D, Schubert S, Dargatz H, Kostenis E, Fahr A, Schubert US, Heinzel T, Imhof D. Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors. Macromolecular Bioscience. 14: 69-80. PMID 23966296 DOI: 10.1002/Mabi.201300213  0.336
2014 Kühl T, Chen M, Teichmann K, Stark A, Imhof D. Ionic liquid 1-ethyl-3-methylimidazolium acetate: an attractive solvent for native chemical ligation of peptides Tetrahedron Letters. 55: 3658-3662. DOI: 10.1016/J.Tetlet.2014.04.102  0.376
2014 Böhm M, Tietze AA, Heimer P, Chen M, Imhof D. Ionic liquids as reaction media for oxidative folding and native chemical ligation of cysteine-containing peptides Journal of Molecular Liquids. 192: 67-70. DOI: 10.1016/J.Molliq.2013.08.020  0.361
2013 Tietze AA, Bordusa F, Giernoth R, Imhof D, Lenzer T, Maass A, Mrestani-Klaus C, Neundorf I, Oum K, Reith D, Stark A. On the nature of interactions between ionic liquids and small amino-acid-based biomolecules. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 14: 4044-64. PMID 24222640 DOI: 10.1002/Cphc.201300736  0.329
2013 Kühl T, Wißbrock A, Goradia N, Sahoo N, Galler K, Neugebauer U, Popp J, Heinemann SH, Ohlenschläger O, Imhof D. Analysis of Fe(III) heme binding to cysteine-containing heme-regulatory motifs in proteins. Acs Chemical Biology. 8: 1785-93. PMID 23730736 DOI: 10.1021/Cb400317X  0.451
2013 Brückner C, Bunz SC, Imhof D, Neusüss C, Scriba GK. Isomerization and epimerization of the aspartyl tetrapeptide Ala-Phe-Asp-GlyOH at pH 10-A CE study. Electrophoresis. 34: 2666-73. PMID 23533053 DOI: 10.1002/Elps.201200685  0.343
2013 Brückner C, Imhof D, Scriba GK. Capillary electrophoretic study of the degradation pathways and kinetics of the aspartyl model tetrapeptide Gly-Phe-Asp-GlyOH in alkaline solution. Journal of Pharmaceutical and Biomedical Analysis. 76: 96-103. PMID 23298912 DOI: 10.1016/J.Jpba.2012.12.012  0.319
2012 Brückner C, Fahr A, Imhof D, Scriba GK. Degradation kinetics of an aspartyl-tripeptide-derived diketopiperazine under forced conditions. Journal of Pharmaceutical Sciences. 101: 4178-90. PMID 22899465 DOI: 10.1002/Jps.23272  0.315
2012 Tietze AA, Heimer P, Stark A, Imhof D. Ionic liquid applications in peptide chemistry: synthesis, purification and analytical characterization processes. Molecules (Basel, Switzerland). 17: 4158-85. PMID 22481538 DOI: 10.3390/Molecules17044158  0.374
2012 Tietze AA, Tietze D, Ohlenschläger O, Leipold E, Ullrich F, Kühl T, Mischo A, Buntkowsky G, Görlach M, Heinemann SH, Imhof D. Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4. Angewandte Chemie (International Ed. in English). 51: 4058-61. PMID 22407516 DOI: 10.1002/Anie.201107011  0.321
2012 Böhm M, Kühl T, Hardes K, Coch R, Arkona C, Schlott B, Steinmetzer T, Imhof D. Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa. Chemmedchem. 7: 326-33. PMID 22162181 DOI: 10.1002/Cmdc.201100405  0.396
2011 Kühl T, Sahoo N, Nikolajski M, Schlott B, Heinemann SH, Imhof D. Determination of hemin-binding characteristics of proteins by a combinatorial peptide library approach. Chembiochem : a European Journal of Chemical Biology. 12: 2846-55. PMID 22045633 DOI: 10.1002/Cbic.201100556  0.445
2011 Tietze D, Voigt S, Mollenhauer D, Tischler M, Imhof D, Gutmann T, González L, Ohlenschläger O, Breitzke H, Görlach M, Buntkowsky G. Revealing the position of the substrate in nickel superoxide dismutase: A model study Angewandte Chemie - International Edition. 50: 2946-2950. PMID 21404375 DOI: 10.1002/Anie.201005027  0.304
2010 Tietze D, Tischler M, Voigt S, Imhof D, Ohlenschläger O, Görlach M, Buntkowsky G. Development of a functional cis-prolyl bond biomimetic and mechanistic implications for nickel superoxide dismutase. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 7572-8. PMID 20461826 DOI: 10.1002/Chem.200903306  0.411
2010 Miloslavina A, Ebert C, Tietze D, Ohlenschläger O, Englert C, Görlach M, Imhof D. An unusual peptide from Conus villepinii: synthesis, solution structure, and cardioactivity. Peptides. 31: 1292-300. PMID 20385188 DOI: 10.1016/J.Peptides.2010.04.002  0.424
2010 Teichmann K, Kühl T, Könnig I, Wieligmann K, Zacharias M, Imhof D. Modulation of SHP-1 phosphatase activity by monovalent and bivalent SH2 phosphopeptide ligands. Biopolymers. 93: 102-12. PMID 19768778 DOI: 10.1002/Bip.21307  0.416
2010 Teichmann K, Niksch T, Wieligmann K, Zacharias M, Imhof D. Synthetic strategies to a backbone-side chain cyclic SHP-1 N-SH2 ligand containing N-functionalized alkyl phosphotyrosine. Protein and Peptide Letters. 17: 809-16. PMID 19747152 DOI: 10.2174/092986610791306779  0.345
2009 Tietze D, Breitzke H, Imhof D, Kothe E, Weston J, Buntkowsky G. New insight into the mode of action of nickel superoxide dismutase by investigating metallopeptide substrate models. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 517-23. PMID 19016282 DOI: 10.1002/Chem.200800870  0.314
2009 Dubs M, Weisser J, Linke R, Pfuch A, Imhof D, Schnabelrauch M. Dextran‐based coating system for the immobilization of cell adhesion promoting molecules on titanium surfaces Materialwissenschaft Und Werkstofftechnik. 40: 853-860. DOI: 10.1002/Mawe.200900504  0.313
2008 Fan Y, Ludewig R, Imhof D, Scriba GK. Development of a capillary electrophoresis-based assay of sirtuin enzymes. Electrophoresis. 29: 3717-23. PMID 18850641 DOI: 10.1002/Elps.200800361  0.39
2008 Musharraf A, Markschies N, Teichmann K, Pankratz S, Landgraf K, Englert C, Imhof D. Eyes absent proteins: characterization of substrate specificity and phosphatase activity of mutants associated with branchial, otic and renal anomalies. Chembiochem : a European Journal of Chemical Biology. 9: 2285-94. PMID 18759246 DOI: 10.1002/Cbic.200800224  0.429
2007 Valkova C, Maerz S, Imhof D, Liebmann C. Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1. Cellular Signalling. 19: 1830-43. PMID 17561374 DOI: 10.1016/J.Cellsig.2007.04.004  0.311
2007 Teichmann K, Winkler R, Hampel K, Trümpler A, Böhmer FD, Imhof D. Monitoring phosphatase reactions of multiple phosphorylated substrates by reversed-phase HPLC. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 853: 204-13. PMID 17416557 DOI: 10.1016/J.Jchromb.2007.03.019  0.396
2006 Hampel K, Kaufhold I, Zacharias M, Böhmer FD, Imhof D. Phosphopeptide ligands of the SHP-1 N-SH2 domain: effects on binding and stimulation of phosphatase activity. Chemmedchem. 1: 869-77. PMID 16902940 DOI: 10.1002/Cmdc.200600037  0.417
2006 Imhof D, Wavreille AS, May A, Zacharias M, Tridandapani S, Pei D. Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position. The Journal of Biological Chemistry. 281: 20271-82. PMID 16702225 DOI: 10.1074/Jbc.M601047200  0.542
2005 Imhof D, Wieligmann K, Hampel K, Nothmann D, Zoda MS, Schmidt-Arras D, Zacharias M, Böhmer FD, Reissmann S. Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1. Journal of Medicinal Chemistry. 48: 1528-39. PMID 15743195 DOI: 10.1021/Jm049151T  0.471
2005 Imhof D, Nothmann D, Zoda MS, Hampel K, Wegert J, Böhmer FD, Reissmann S. Synthesis of linear and cyclic phosphopeptides as ligands for the N-terminal SH2-domain of protein tyrosine phosphatase SHP-1. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 390-400. PMID 15635669 DOI: 10.1002/Psc.631  0.422
2004 Reissmann S, Imhof D. Development of conformationally restricted analogues of bradykinin and somatostatin using constrained amino acids and different types of cyclization. Current Medicinal Chemistry. 11: 2823-44. PMID 15544478 DOI: 10.2174/0929867043364135  0.375
2004 Frank C, Burkhardt C, Imhof D, Ringel J, Zschörnig O, Wieligmann K, Zacharias M, Böhmer FD. Effective Dephosphorylation of Src Substrates by SHP-1 Journal of Biological Chemistry. 279: 11375-11383. PMID 14699166 DOI: 10.1074/Jbc.M309096200  0.333
2003 Nguyen HH, Imhof D, Kronen M, Gräfe U, Reissmann S. Circular dichroism studies of ampullosporin-A analogues. Journal of Peptide Science : An Official Publication of the European Peptide Society. 9: 714-28. PMID 14658791 DOI: 10.1002/Psc.459  0.371
2002 Nguyen HH, Imhof D, Kronen M, Schlegel B, Härtl A, Gräfe U, Gera L, Reissmann S. Synthesis and biological evaluation of analogues of the peptaibol ampullosporin A. Journal of Medicinal Chemistry. 45: 2781-7. PMID 12061880 DOI: 10.1021/Jm0208018  0.407
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