Year |
Citation |
Score |
2024 |
Pepanian A, Binbay FA, Pei D, Imhof D. Design, synthesis, and analysis of macrobicyclic peptides for targeting the Gαi protein. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3565. PMID 38232955 DOI: 10.1002/psc.3565 |
0.547 |
|
2023 |
Pepanian A, Binbay FA, Roy S, Nubbemeyer B, Koley A, Rhodes CA, Ammer H, Pei D, Ghosh P, Imhof D. Bicyclic Peptide Library Screening for the Identification of Gαi Protein Modulators. Journal of Medicinal Chemistry. PMID 37587416 DOI: 10.1021/acs.jmedchem.3c00873 |
0.54 |
|
2022 |
Nubbemeyer B, Paul George AA, Kühl T, Pepanian A, Beck MS, Maghraby R, Shetab Boushehri M, Muehlhaupt M, Pfeil EM, Annala SK, Ammer H, Imhof D, Pei D. Targeting Gαi/s Proteins with Peptidyl Nucleotide Exchange Modulators. Acs Chemical Biology. PMID 35042325 DOI: 10.1021/acschembio.1c00929 |
0.524 |
|
2020 |
Schmitz T, Pengelley S, Belau E, Suckau D, Imhof D. LC-Trapped Ion Mobility Spectrometry-TOF MS Differentiation of 2- and 3-Disulfide-Bonded Isomers of the μ-Conotoxin PIIIA. Analytical Chemistry. 92: 10920-10924. PMID 32806900 DOI: 10.1021/Acs.Analchem.0C02151 |
0.319 |
|
2020 |
Imhof D, Hopp MT, Alhanafi N, Paul George AA, Hamedani NS, Biswas A, Oldenburg J, Pötzsch B. Molecular insights and functional consequences of the interaction of heme with activated protein C. Antioxidants & Redox Signaling. PMID 32705892 DOI: 10.1089/Ars.2019.7992 |
0.316 |
|
2020 |
Bäuml CA, Paul George AA, Schmitz T, Sommerfeld P, Pietsch M, Podsiadlowski L, Steinmetzer T, Biswas A, Imhof D. Distinct 3-disulfide-bonded isomers of tridegin differentially inhibit coagulation factor XIIIa: The influence of structural stability on bioactivity. European Journal of Medicinal Chemistry. 201: 112474. PMID 32698061 DOI: 10.1016/J.Ejmech.2020.112474 |
0.414 |
|
2020 |
Hopp MT, Schmalohr BF, Kühl T, Detzel MS, Wißbrock A, Imhof D. Heme Determination and Quantification Methods and Their Suitability for Practical Applications and Everyday Use. Analytical Chemistry. PMID 32490668 DOI: 10.1021/Acs.Analchem.0C00415 |
0.3 |
|
2020 |
Schmitz T, Bäuml CA, Imhof D. Inhibitors of blood coagulation factor XIIIa. Analytical Biochemistry. 113708. PMID 32335064 DOI: 10.1016/J.Ab.2020.113708 |
0.319 |
|
2020 |
Syllwasschy BF, Beck MS, Družeta I, Hopp MT, Ramoji A, Neugebauer U, Nozinovic S, Menche D, Willbold D, Ohlenschläger O, Kühl T, Imhof D. High-affinity binding and catalytic activity of His/Tyr-based sequences: Extending heme-regulatory motifs beyond CP. Biochimica Et Biophysica Acta. General Subjects. 129603. PMID 32234408 DOI: 10.1016/J.Bbagen.2020.129603 |
0.463 |
|
2020 |
Paul George AA, Lacerda M, Syllwasschy BF, Hopp MT, Wißbrock A, Imhof D. HeMoQuest: a webserver for qualitative prediction of transient heme binding to protein motifs. Bmc Bioinformatics. 21: 124. PMID 32216745 DOI: 10.1186/S12859-020-3420-2 |
0.357 |
|
2019 |
Singh S, Dodt J, Volkers P, Hethershaw E, Philippou H, Ivaskevicius V, Imhof D, Oldenburg J, Biswas A. Structure functional insights into calcium binding during the activation of coagulation factor XIII A. Scientific Reports. 9: 11324. PMID 31383913 DOI: 10.1038/S41598-019-47815-Z |
0.305 |
|
2019 |
Kumar A, Bellstedt P, Wiedemann C, Wißbrock A, Imhof D, Ramachandran R, Ohlenschläger O. NMR experiments on the transient interaction of the intrinsically disordered N-terminal peptide of cystathionine-β-synthase with heme. Journal of Magnetic Resonance (San Diego, Calif. : 1997). PMID 31345774 DOI: 10.1016/J.Jmr.2019.07.048 |
0.36 |
|
2019 |
Paul George AA, Heimer P, Leipold E, Schmitz T, Kaufmann D, Tietze D, Heinemann SH, Imhof D. Effect of Conformational Diversity on the Bioactivity of µ-Conotoxin PIIIA Disulfide Isomers. Marine Drugs. 17. PMID 31269696 DOI: 10.3390/Md17070390 |
0.354 |
|
2019 |
Bäuml CA, Schmitz T, Paul George AA, Sudarsanam M, Hardes K, Steinmetzer T, Holle LA, Wolberg AS, Pötzsch B, Oldenburg J, Biswas A, Imhof D. COAGULATION FACTOR XIIIA-INHIBITOR TRIDEGIN: ON THE ROLE OF DISULFIDE BONDS FOR FOLDING, STABILITY, AND FUNCTION. Journal of Medicinal Chemistry. PMID 30852892 DOI: 10.1021/Acs.Jmedchem.8B01982 |
0.388 |
|
2019 |
Wißbrock A, Paul George AA, Brewitz HH, Kühl T, Imhof D. The Molecular Basis of Transient Heme-Protein Interactions: Analysis, Concept and Implementation. Bioscience Reports. PMID 30622148 DOI: 10.1042/Bsr20181940 |
0.391 |
|
2018 |
Paul George AA, Heimer P, Maaß A, Hamaekers J, Hofmann-Apitius M, Biswas A, Imhof D. Insights into the Folding of Disulfide-Rich μ-Conotoxins. Acs Omega. 3: 12330-12340. PMID 30411002 DOI: 10.1021/acsomega.8b01465 |
0.302 |
|
2018 |
Heimer P, Schmitz T, Bäuml CA, Imhof D. Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities. Journal of Visualized Experiments : Jove. PMID 30346393 DOI: 10.3791/58368 |
0.419 |
|
2018 |
Imhof D, Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM. Deciphering specificity determinants for FR900359-derived Gαq inhibitors based on computational and structure-activity studies. Chemmedchem. PMID 29873888 DOI: 10.1002/Cmdc.201800304 |
0.4 |
|
2018 |
Oppermann S, Oppermann C, Böhm M, Kühl T, Imhof D, Kragl U. Quantification of amino acids and peptides in an ionic liquid based aqueous two-phase system by LC-MS analysis. Amb Express. 8: 66. PMID 29696483 DOI: 10.1186/S13568-018-0596-1 |
0.364 |
|
2018 |
Kumar A, Wißbrock A, Goradia N, Bellstedt P, Ramachandran R, Imhof D, Ohlenschläger O. Heme interaction of the intrinsically disordered N-terminal peptide segment of human cystathionine-β-synthase. Scientific Reports. 8: 2474. PMID 29410458 DOI: 10.1038/S41598-018-20841-Z |
0.381 |
|
2018 |
Heimer P, Tietze AA, Bäuml CA, Resemann A, Mayer FJ, Suckau D, Ohlenschläger O, Tietze D, Imhof D. Conformational μ-Conotoxin PIIIA Isomers Revisited: Impact of Cysteine Pairing on Disulfide-Bond Assignment and Structure Elucidation. Analytical Chemistry. PMID 29397705 DOI: 10.1021/Acs.Analchem.7B04854 |
0.395 |
|
2017 |
Tietze D, Sartorius J, Koley Seth B, Herr K, Heimer P, Imhof D, Mollenhauer D, Buntkowsky G. New insights into the mechanism of nickel superoxide degradation from studies of model peptides. Scientific Reports. 7: 17194. PMID 29222438 DOI: 10.1038/S41598-017-17446-3 |
0.375 |
|
2016 |
Brewitz HH, Hagelueken G, Imhof D. Structural and functional diversity of transient heme binding to bacterial proteins. Biochimica Et Biophysica Acta. PMID 28012743 DOI: 10.1016/J.Bbagen.2016.12.021 |
0.303 |
|
2016 |
Wißbrock A, Kühl T, Silbermann K, Becker AJ, Ohlenschläger O, Imhof D. Synthesis and Evaluation of Amyloid β Derived and Amyloid β Independent Enhancers of the Peroxidase-like Activity of Heme. Journal of Medicinal Chemistry. PMID 27976903 DOI: 10.1021/Acs.Jmedchem.6B01432 |
0.395 |
|
2016 |
Blaurock N, Schmerler D, Hünniger K, Kurzai O, Ludewig K, Baier M, Brunkhorst FM, Imhof D, Kiehntopf M. C-Terminal Alpha-1 Antitrypsin Peptide: A New Sepsis Biomarker with Immunomodulatory Function. Mediators of Inflammation. 2016: 6129437. PMID 27382189 DOI: 10.1155/2016/6129437 |
0.333 |
|
2016 |
Tietze D, Leipold E, Heimer P, Böhm M, Winschel W, Imhof D, Heinemann SH, Tietze AA. Molecular interaction of δ-conopeptide EVIA with voltage-gated Na(+) channels. Biochimica Et Biophysica Acta. PMID 27316322 DOI: 10.1016/J.Bbagen.2016.06.013 |
0.321 |
|
2016 |
Brewitz HH, Goradia N, Schubert E, Galler K, Kühl T, Syllwasschy B, Popp J, Neugebauer U, Hagelueken G, Schiemann O, Ohlenschläger O, Imhof D. Heme interacts with histidine- and tyrosine-based protein motifs and inhibits enzymatic activity of chloramphenicol acetyltransferase from Escherichiacoli. Biochimica Et Biophysica Acta. PMID 27015758 DOI: 10.1016/J.Bbagen.2016.03.027 |
0.427 |
|
2015 |
Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, ... ... Imhof D, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156. PMID 26658454 DOI: 10.1038/Ncomms10156 |
0.317 |
|
2015 |
Brewitz HH, Kühl T, Goradia N, Galler K, Popp J, Neugebauer U, Ohlenschläger O, Imhof D. Role of the Chemical Environment beyond the Coordination Site: Structural Insight into Fe(III) Protoporphyrin Binding to Cysteine-Based Heme-Regulatory Protein Motifs. Chembiochem : a European Journal of Chemical Biology. 16: 2216-24. PMID 26260099 DOI: 10.1002/Cbic.201500331 |
0.418 |
|
2015 |
Schubert E, Florin N, Duthie F, Henning Brewitz H, Kühl T, Imhof D, Hagelueken G, Schiemann O. Spectroscopic studies on peptides and proteins with cysteine-containing heme regulatory motifs (HRM). Journal of Inorganic Biochemistry. 148: 49-56. PMID 26050879 DOI: 10.1016/J.Jinorgbio.2015.05.008 |
0.428 |
|
2015 |
Chen M, Heimer P, Imhof D. Synthetic strategies for polypeptides and proteins by chemical ligation. Amino Acids. 47: 1283-99. PMID 25894893 DOI: 10.1007/S00726-015-1982-5 |
0.413 |
|
2014 |
Böhm M, Bäuml CA, Hardes K, Steinmetzer T, Roeser D, Schaub Y, Than ME, Biswas A, Imhof D. Novel insights into structure and function of factor XIIIa-inhibitor tridegin. Journal of Medicinal Chemistry. 57: 10355-65. PMID 25415134 DOI: 10.1021/Jm501058G |
0.44 |
|
2014 |
Heimer P, Tietze AA, Böhm M, Giernoth R, Kuchenbuch A, Stark A, Leipold E, Heinemann SH, Kandt C, Imhof D. Application of room-temperature aprotic and protic ionic liquids for oxidative folding of cysteine-rich peptides. Chembiochem : a European Journal of Chemical Biology. 15: 2754-65. PMID 25376613 DOI: 10.1002/Cbic.201402356 |
0.383 |
|
2014 |
Schmitz AL, Schrage R, Gaffal E, Charpentier TH, Wiest J, Hiltensperger G, Morschel J, Hennen S, Häußler D, Horn V, Wenzel D, Grundmann M, Büllesbach KM, Schröder R, Brewitz HH, ... ... Imhof D, et al. A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation. Chemistry & Biology. 21: 890-902. PMID 25036778 DOI: 10.1016/J.Chembiol.2014.06.003 |
0.333 |
|
2014 |
Hennig D, Schubert S, Dargatz H, Kostenis E, Fahr A, Schubert US, Heinzel T, Imhof D. Novel insights into appropriate encapsulation methods for bioactive compounds into polymers: a study with peptides and HDAC inhibitors. Macromolecular Bioscience. 14: 69-80. PMID 23966296 DOI: 10.1002/Mabi.201300213 |
0.336 |
|
2014 |
Kühl T, Chen M, Teichmann K, Stark A, Imhof D. Ionic liquid 1-ethyl-3-methylimidazolium acetate: an attractive solvent for native chemical ligation of peptides Tetrahedron Letters. 55: 3658-3662. DOI: 10.1016/J.Tetlet.2014.04.102 |
0.376 |
|
2014 |
Böhm M, Tietze AA, Heimer P, Chen M, Imhof D. Ionic liquids as reaction media for oxidative folding and native chemical ligation of cysteine-containing peptides Journal of Molecular Liquids. 192: 67-70. DOI: 10.1016/J.Molliq.2013.08.020 |
0.361 |
|
2013 |
Tietze AA, Bordusa F, Giernoth R, Imhof D, Lenzer T, Maass A, Mrestani-Klaus C, Neundorf I, Oum K, Reith D, Stark A. On the nature of interactions between ionic liquids and small amino-acid-based biomolecules. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 14: 4044-64. PMID 24222640 DOI: 10.1002/Cphc.201300736 |
0.329 |
|
2013 |
Kühl T, Wißbrock A, Goradia N, Sahoo N, Galler K, Neugebauer U, Popp J, Heinemann SH, Ohlenschläger O, Imhof D. Analysis of Fe(III) heme binding to cysteine-containing heme-regulatory motifs in proteins. Acs Chemical Biology. 8: 1785-93. PMID 23730736 DOI: 10.1021/Cb400317X |
0.451 |
|
2013 |
Brückner C, Bunz SC, Imhof D, Neusüss C, Scriba GK. Isomerization and epimerization of the aspartyl tetrapeptide Ala-Phe-Asp-GlyOH at pH 10-A CE study. Electrophoresis. 34: 2666-73. PMID 23533053 DOI: 10.1002/Elps.201200685 |
0.343 |
|
2013 |
Brückner C, Imhof D, Scriba GK. Capillary electrophoretic study of the degradation pathways and kinetics of the aspartyl model tetrapeptide Gly-Phe-Asp-GlyOH in alkaline solution. Journal of Pharmaceutical and Biomedical Analysis. 76: 96-103. PMID 23298912 DOI: 10.1016/J.Jpba.2012.12.012 |
0.319 |
|
2012 |
Brückner C, Fahr A, Imhof D, Scriba GK. Degradation kinetics of an aspartyl-tripeptide-derived diketopiperazine under forced conditions. Journal of Pharmaceutical Sciences. 101: 4178-90. PMID 22899465 DOI: 10.1002/Jps.23272 |
0.315 |
|
2012 |
Tietze AA, Heimer P, Stark A, Imhof D. Ionic liquid applications in peptide chemistry: synthesis, purification and analytical characterization processes. Molecules (Basel, Switzerland). 17: 4158-85. PMID 22481538 DOI: 10.3390/Molecules17044158 |
0.374 |
|
2012 |
Tietze AA, Tietze D, Ohlenschläger O, Leipold E, Ullrich F, Kühl T, Mischo A, Buntkowsky G, Görlach M, Heinemann SH, Imhof D. Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4. Angewandte Chemie (International Ed. in English). 51: 4058-61. PMID 22407516 DOI: 10.1002/Anie.201107011 |
0.321 |
|
2012 |
Böhm M, Kühl T, Hardes K, Coch R, Arkona C, Schlott B, Steinmetzer T, Imhof D. Synthesis and functional characterization of tridegin and its analogues: inhibitors and substrates of factor XIIIa. Chemmedchem. 7: 326-33. PMID 22162181 DOI: 10.1002/Cmdc.201100405 |
0.396 |
|
2011 |
Kühl T, Sahoo N, Nikolajski M, Schlott B, Heinemann SH, Imhof D. Determination of hemin-binding characteristics of proteins by a combinatorial peptide library approach. Chembiochem : a European Journal of Chemical Biology. 12: 2846-55. PMID 22045633 DOI: 10.1002/Cbic.201100556 |
0.445 |
|
2011 |
Tietze D, Voigt S, Mollenhauer D, Tischler M, Imhof D, Gutmann T, González L, Ohlenschläger O, Breitzke H, Görlach M, Buntkowsky G. Revealing the position of the substrate in nickel superoxide dismutase: A model study Angewandte Chemie - International Edition. 50: 2946-2950. PMID 21404375 DOI: 10.1002/Anie.201005027 |
0.304 |
|
2010 |
Tietze D, Tischler M, Voigt S, Imhof D, Ohlenschläger O, Görlach M, Buntkowsky G. Development of a functional cis-prolyl bond biomimetic and mechanistic implications for nickel superoxide dismutase. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 7572-8. PMID 20461826 DOI: 10.1002/Chem.200903306 |
0.411 |
|
2010 |
Miloslavina A, Ebert C, Tietze D, Ohlenschläger O, Englert C, Görlach M, Imhof D. An unusual peptide from Conus villepinii: synthesis, solution structure, and cardioactivity. Peptides. 31: 1292-300. PMID 20385188 DOI: 10.1016/J.Peptides.2010.04.002 |
0.424 |
|
2010 |
Teichmann K, Kühl T, Könnig I, Wieligmann K, Zacharias M, Imhof D. Modulation of SHP-1 phosphatase activity by monovalent and bivalent SH2 phosphopeptide ligands. Biopolymers. 93: 102-12. PMID 19768778 DOI: 10.1002/Bip.21307 |
0.416 |
|
2010 |
Teichmann K, Niksch T, Wieligmann K, Zacharias M, Imhof D. Synthetic strategies to a backbone-side chain cyclic SHP-1 N-SH2 ligand containing N-functionalized alkyl phosphotyrosine. Protein and Peptide Letters. 17: 809-16. PMID 19747152 DOI: 10.2174/092986610791306779 |
0.345 |
|
2009 |
Tietze D, Breitzke H, Imhof D, Kothe E, Weston J, Buntkowsky G. New insight into the mode of action of nickel superoxide dismutase by investigating metallopeptide substrate models. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 517-23. PMID 19016282 DOI: 10.1002/Chem.200800870 |
0.314 |
|
2009 |
Dubs M, Weisser J, Linke R, Pfuch A, Imhof D, Schnabelrauch M. Dextran‐based coating system for the immobilization of cell adhesion promoting molecules on titanium surfaces Materialwissenschaft Und Werkstofftechnik. 40: 853-860. DOI: 10.1002/Mawe.200900504 |
0.313 |
|
2008 |
Fan Y, Ludewig R, Imhof D, Scriba GK. Development of a capillary electrophoresis-based assay of sirtuin enzymes. Electrophoresis. 29: 3717-23. PMID 18850641 DOI: 10.1002/Elps.200800361 |
0.39 |
|
2008 |
Musharraf A, Markschies N, Teichmann K, Pankratz S, Landgraf K, Englert C, Imhof D. Eyes absent proteins: characterization of substrate specificity and phosphatase activity of mutants associated with branchial, otic and renal anomalies. Chembiochem : a European Journal of Chemical Biology. 9: 2285-94. PMID 18759246 DOI: 10.1002/Cbic.200800224 |
0.429 |
|
2007 |
Valkova C, Maerz S, Imhof D, Liebmann C. Protein kinase Cepsilon may act as EGF-inducible scaffold protein for phospholipase Cgamma1. Cellular Signalling. 19: 1830-43. PMID 17561374 DOI: 10.1016/J.Cellsig.2007.04.004 |
0.311 |
|
2007 |
Teichmann K, Winkler R, Hampel K, Trümpler A, Böhmer FD, Imhof D. Monitoring phosphatase reactions of multiple phosphorylated substrates by reversed-phase HPLC. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 853: 204-13. PMID 17416557 DOI: 10.1016/J.Jchromb.2007.03.019 |
0.396 |
|
2006 |
Hampel K, Kaufhold I, Zacharias M, Böhmer FD, Imhof D. Phosphopeptide ligands of the SHP-1 N-SH2 domain: effects on binding and stimulation of phosphatase activity. Chemmedchem. 1: 869-77. PMID 16902940 DOI: 10.1002/Cmdc.200600037 |
0.417 |
|
2006 |
Imhof D, Wavreille AS, May A, Zacharias M, Tridandapani S, Pei D. Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position. The Journal of Biological Chemistry. 281: 20271-82. PMID 16702225 DOI: 10.1074/Jbc.M601047200 |
0.542 |
|
2005 |
Imhof D, Wieligmann K, Hampel K, Nothmann D, Zoda MS, Schmidt-Arras D, Zacharias M, Böhmer FD, Reissmann S. Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1. Journal of Medicinal Chemistry. 48: 1528-39. PMID 15743195 DOI: 10.1021/Jm049151T |
0.471 |
|
2005 |
Imhof D, Nothmann D, Zoda MS, Hampel K, Wegert J, Böhmer FD, Reissmann S. Synthesis of linear and cyclic phosphopeptides as ligands for the N-terminal SH2-domain of protein tyrosine phosphatase SHP-1. Journal of Peptide Science : An Official Publication of the European Peptide Society. 11: 390-400. PMID 15635669 DOI: 10.1002/Psc.631 |
0.422 |
|
2004 |
Reissmann S, Imhof D. Development of conformationally restricted analogues of bradykinin and somatostatin using constrained amino acids and different types of cyclization. Current Medicinal Chemistry. 11: 2823-44. PMID 15544478 DOI: 10.2174/0929867043364135 |
0.375 |
|
2004 |
Frank C, Burkhardt C, Imhof D, Ringel J, Zschörnig O, Wieligmann K, Zacharias M, Böhmer FD. Effective Dephosphorylation of Src Substrates by SHP-1 Journal of Biological Chemistry. 279: 11375-11383. PMID 14699166 DOI: 10.1074/Jbc.M309096200 |
0.333 |
|
2003 |
Nguyen HH, Imhof D, Kronen M, Gräfe U, Reissmann S. Circular dichroism studies of ampullosporin-A analogues. Journal of Peptide Science : An Official Publication of the European Peptide Society. 9: 714-28. PMID 14658791 DOI: 10.1002/Psc.459 |
0.371 |
|
2002 |
Nguyen HH, Imhof D, Kronen M, Schlegel B, Härtl A, Gräfe U, Gera L, Reissmann S. Synthesis and biological evaluation of analogues of the peptaibol ampullosporin A. Journal of Medicinal Chemistry. 45: 2781-7. PMID 12061880 DOI: 10.1021/Jm0208018 |
0.407 |
|
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