| Year |
Citation |
Score |
| 2018 |
Peek J, Lilic M, Montiel D, Milshteyn A, Woodworth I, Biggins JB, Ternei MA, Calle PY, Danziger M, Warrier T, Saito K, Braffman N, Fay A, Glickman MS, Darst SA, et al. Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nature Communications. 9: 4147. PMID 30297823 DOI: 10.1038/S41467-018-06587-2 |
0.519 |
|
| 2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.677 |
|
| 2014 |
Biggins JB, Kang HS, Ternei MA, DeShazer D, Brady SF. The chemical arsenal of Burkholderia pseudomallei is essential for pathogenicity. Journal of the American Chemical Society. 136: 9484-90. PMID 24884988 DOI: 10.1021/ja504617n |
0.559 |
|
| 2014 |
Biggins JB, Kang HS, Ternei MA, Deshazer D, Brady SF. The chemical arsenal of burkholderia pseudomallei is essential for pathogenicity Journal of the American Chemical Society. 136: 9484-9490. DOI: 10.1021/ja504617n |
0.462 |
|
| 2012 |
Biggins JB, Ternei MA, Brady SF. Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens. Journal of the American Chemical Society. 134: 13192-5. PMID 22765305 DOI: 10.1021/ja3052156 |
0.557 |
|
| 2011 |
Biggins JB, Gleber CD, Brady SF. Acyldepsipeptide HDAC inhibitor production induced in Burkholderia thailandensis. Organic Letters. 13: 1536-9. PMID 21348454 DOI: 10.1021/ol200225v |
0.558 |
|
| 2011 |
Biggins JB, Liu X, Feng Z, Brady SF. Metabolites from the induced expression of cryptic single operons found in the genome of Burkholderia pseudomallei. Journal of the American Chemical Society. 133: 1638-41. PMID 21247113 DOI: 10.1021/ja1087369 |
0.552 |
|
| 2010 |
Sauers DJ, Temburni MK, Biggins JB, Ceo LM, Galileo DS, Koh JT. Light-activated gene expression directs segregation of co-cultured cells in vitro. Acs Chemical Biology. 5: 313-20. PMID 20050613 DOI: 10.1021/Cb9002305 |
0.434 |
|
| 2007 |
Biggins JB, Hashimoto A, Koh JT. Photocaged agonist for an analogue-specific form of the vitamin D receptor. Chembiochem : a European Journal of Chemical Biology. 8: 799-803. PMID 17393546 DOI: 10.1002/Cbic.200600497 |
0.679 |
|
| 2007 |
Biggins JB, Koh JT. Chemical biology of steroid and nuclear hormone receptors. Current Opinion in Chemical Biology. 11: 99-110. PMID 17188557 DOI: 10.1016/J.Cbpa.2006.10.042 |
0.648 |
|
| 2006 |
Biggins JB, Prudent JR, Marshall DJ, Thorson JS. A continuous assay for DNA cleavage using molecular break lights. Methods in Molecular Biology (Clifton, N.J.). 335: 83-92. PMID 16785622 DOI: 10.1385/1-59745-069-3:83 |
0.483 |
|
| 2005 |
Koh JT, Biggins JB. Ligand-receptor engineering and its application towards the complementation of genetic disease and target identification. Current Topics in Medicinal Chemistry. 5: 413-20. PMID 15892683 DOI: 10.2174/1568026053828420 |
0.641 |
|
| 2003 |
Biggins JB, Onwueme KC, Thorson JS. Resistance to enediyne antitumor antibiotics by CalC self-sacrifice. Science (New York, N.Y.). 301: 1537-41. PMID 12970566 DOI: 10.1126/Science.1086695 |
0.449 |
|
| 2003 |
Yang J, Fu X, Jia Q, Shen J, Biggins JB, Jiang J, Zhao J, Schmidt JJ, Wang PG, Thorson JS. Studies on the substrate specificity of Escherichia coli galactokinase. Organic Letters. 5: 2223-6. PMID 12816414 DOI: 10.1021/Ol034642D |
0.504 |
|
| 2003 |
Albermann C, Soriano A, Jiang J, Vollmer H, Biggins JB, Barton WA, Lesniak J, Nikolov DB, Thorson JS. Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization. Organic Letters. 5: 933-6. PMID 12633109 DOI: 10.1021/Ol0341086 |
0.701 |
|
| 2002 |
Losey HC, Jiang J, Biggins JB, Oberthür M, Ye XY, Dong SD, Kahne D, Thorson JS, Walsh CT. Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chemistry & Biology. 9: 1305-14. PMID 12498883 DOI: 10.1016/S1074-5521(02)00270-3 |
0.463 |
|
| 2002 |
Barton WA, Biggins JB, Jiang J, Thorson JS, Nikolov DB. Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering. Proceedings of the National Academy of Sciences of the United States of America. 99: 13397-402. PMID 12374866 DOI: 10.1073/Pnas.192468299 |
0.467 |
|
| 2001 |
Jiang J, Biggins JB, Thorson JS. Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl Derivatives. Angewandte Chemie (International Ed. in English). 40: 1502-1505. PMID 29712364 DOI: 10.1002/1521-3773(20010417)40:8<1502::Aid-Anie1502>3.0.Co;2-K |
0.437 |
|
| 2001 |
Barton WA, Lesniak J, Biggins JB, Jeffrey PD, Jiang J, Rajashankar KR, Thorson JS, Nikolov DB. Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization. Nature Structural Biology. 8: 545-51. PMID 11373625 DOI: 10.1038/88618 |
0.494 |
|
| 2001 |
Jiang J, Biggins JB, Thorson JS. Expanding the Pyrimidine Diphosphosugar Repertoire: The Chemoenzymatic Synthesis of Amino- and Acetamidoglucopyranosyl Derivatives This contribution was supported by the National Institutes of Health (GM58196 and CA84374), a Cancer Center Support Grant (CA-08748), and a grant from the Special Projects Committee of the Society of Memorial Sloan-Kettering Cancer Center. J.S.T. is an Alfred P. Sloan Research Fellow and a Rita Allen Foundation Scholar. Angewandte Chemie (International Ed. in English). 40: 1502-1505. PMID 11317315 DOI: 10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K |
0.404 |
|
| 2000 |
Biggins JB, Prudent JR, Marshall DJ, Ruppen M, Thorson JS. A continuous assay for DNA cleavage: The application of 'break lights' to enediynes, iron-dependent and nucleases Proceedings of the National Academy of Sciences of the United States of America. 97: 13537-13542. PMID 11095715 DOI: 10.1073/Pnas.240460997 |
0.495 |
|
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