Year |
Citation |
Score |
2022 |
Bagatella S, Haghayegh Jahromi N, Monney C, Polidori M, Gall FM, Marchionatti E, Serra F, Riedl R, Engelhardt B, Oevermann A. Bovine neutrophil chemotaxis to Listeria monocytogenes in neurolisteriosis depends on microglia-released rather than bacterial factors. Journal of Neuroinflammation. 19: 304. PMID 36527076 DOI: 10.1186/s12974-022-02653-1 |
0.705 |
|
2022 |
Kiss C, Gall FM, Dreier B, Adams M, Riedl R, Plückthun A, Mittl PRE. Structure of a hydrophobic leucinostatin derivative determined by host lattice display. Acta Crystallographica. Section D, Structural Biology. 78: 1439-1450. PMID 36458615 DOI: 10.1107/S2059798322010762 |
0.73 |
|
2022 |
Brand M, Bommeli EB, Rütimann M, Lindenmann U, Riedl R. Discovery of a Dual SENP1 and SENP2 Inhibitor. International Journal of Molecular Sciences. 23. PMID 36292935 DOI: 10.3390/ijms232012085 |
0.765 |
|
2022 |
Sabani B, Brand M, Albert I, Inderbitzin J, Eichenseher F, Schmelcher M, Rohrer J, Riedl R, Lehmann S. A novel surface functionalization platform to prime extracellular vesicles for targeted therapy and diagnostic imaging. Nanomedicine : Nanotechnology, Biology, and Medicine. 102607. PMID 36167305 DOI: 10.1016/j.nano.2022.102607 |
0.49 |
|
2021 |
Shrestha N, Gall FM, Mathieu C, Hierweger MM, Brügger M, Alves MP, Vesin J, Banfi D, Kalbermatter D, Horvat B, Chambon M, Turcatti G, Fotiadis D, Riedl R, Plattet P. Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier. Mbio. e0262121. PMID 34724816 DOI: 10.1128/mBio.02621-21 |
0.736 |
|
2021 |
Fischer T, Riedl R. Paracelsus' legacy in the faunal realm: Drugs deriving from animal toxins. Drug Discovery Today. PMID 34678490 DOI: 10.1016/j.drudis.2021.10.003 |
0.373 |
|
2021 |
Brand M, Wang L, Agnello S, Gazzola S, Gall FM, Raguž L, Kaiser M, Schmidt RS, Ritschl A, Jelk J, Hemphill A, Mäser P, Bütikofer P, Adams M, Riedl R. Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action. Angewandte Chemie (International Ed. in English). PMID 33730410 DOI: 10.1002/anie.202102153 |
0.723 |
|
2021 |
Zizzari AT, Pliatsika D, Gall FM, Fischer T, Riedl R. New perspectives in oral peptide delivery. Drug Discovery Today. PMID 33497830 DOI: 10.1016/j.drudis.2021.01.020 |
0.739 |
|
2021 |
Shrestha N, Gall FM, Vesin J, Chambon M, Turcatti G, Fotiadis D, Riedl R, Plattet P. Antiviral Screen against Canine Distemper Virus-Induced Membrane Fusion Activity. Viruses. 13. PMID 33477492 DOI: 10.3390/v13010128 |
0.744 |
|
2020 |
Neidhart B, Kowalska M, Valentin JDP, Gall FM, Ren Q, Riedl R, Pot S, Rottmar M. Tissue Inhibitor of Metalloproteinase (TIMP) Peptidomimetic as an Adjunctive Therapy for Infectious Keratitis. Biomacromolecules. PMID 33347749 DOI: 10.1021/acs.biomac.0c01473 |
0.731 |
|
2020 |
Fischer T, Riedl R. Challenges with matrix metalloproteinase inhibition and future drug discovery avenues. Expert Opinion On Drug Discovery. 1-14. PMID 32921161 DOI: 10.1080/17460441.2020.1819235 |
0.499 |
|
2020 |
Kalbermatter D, Shrestha N, Gall FM, Wyss M, Riedl R, Plattet P, Fotiadis D. Cryo-EM structure of the prefusion state of canine distemper virus fusion protein ectodomain. Journal of Structural Biology: X. 4: 100021. PMID 32647825 DOI: 10.1016/j.yjsbx.2020.100021 |
0.734 |
|
2020 |
Lindenmann U, Brand M, Gall F, Frasson D, Hunziker L, Kroslakova I, Sievers M, Riedl R. Discovery of a novel Class of potent and selective non-competitive Sentrin-specific Protease 1 Inhibitors. Chemmedchem. PMID 32083799 DOI: 10.1002/Cmdc.202000067 |
0.748 |
|
2019 |
Höck S, Riedl R. CyBy: a strongly typed, purely functional framework for chemical data management. Journal of Cheminformatics. 11: 80. PMID 33430953 DOI: 10.1186/S13321-019-0403-2 |
0.708 |
|
2019 |
Fischer T, Riedl R. Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation. Molecules (Basel, Switzerland). 24. PMID 31216704 DOI: 10.3390/Molecules24122265 |
0.493 |
|
2019 |
Fischer T, Gazzola S, Riedl R. Approaching Target Selectivity by De Novo Drug Design. Expert Opinion On Drug Discovery. 1-13. PMID 31179763 DOI: 10.1080/17460441.2019.1615435 |
0.749 |
|
2019 |
Fischer T, Koulas SM, Tsagkarakou AS, Kyriakis E, Stravodimos GA, Skamnaki VT, Liggri PGV, Zographos SE, Riedl R, Leonidas DD. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl--acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Molecules (Basel, Switzerland). 24. PMID 30987252 DOI: 10.3390/Molecules24071322 |
0.483 |
|
2019 |
Fischer T, Senn N, Riedl R. Design and Structural Evolution of Matrix Metalloproteinase Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30720221 DOI: 10.1002/Chem.201805361 |
0.701 |
|
2019 |
Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Drug design inspired by Nature: Crystallographic detection of auto-tailored protease inhibitor template. Angewandte Chemie (International Ed. in English). PMID 30615822 DOI: 10.1002/Anie.201812348 |
0.787 |
|
2019 |
Fischer T, Senn N, Riedl R. Frontispiece: Design and Structural Evolution of Matrix Metalloproteinase Inhibitors Chemistry – a European Journal. 25. DOI: 10.1002/Chem.201983461 |
0.672 |
|
2019 |
Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Cover Picture: Drug Design Inspired by Nature: Crystallographic Detection of an Auto‐Tailored Protease Inhibitor Template (Angew. Chem. Int. Ed. 12/2019) Angewandte Chemie International Edition. 58: 3653-3653. DOI: 10.1002/Anie.201901671 |
0.776 |
|
2019 |
Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Titelbild: Von der Natur inspiriertes Wirkstoffdesign: kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts (Angew. Chem. 12/2019) Angewandte Chemie. 131: 3691-3691. DOI: 10.1002/Ange.201901671 |
0.756 |
|
2019 |
Gall FM, Hohl D, Frasson D, Wermelinger T, Mittl PRE, Sievers M, Riedl R. Von der Natur inspiriertes Wirkstoffdesign: kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts Angewandte Chemie. 131: 4091-4096. DOI: 10.1002/Ange.201812348 |
0.755 |
|
2019 |
Agnello S, Brand M, Chellat MF, Gazzola S, Riedl R. Eine strukturelle Evaluierung medizinalchemischer Strategien gegen Wirkstoffresistenzen Angewandte Chemie. 131: 3336-3383. DOI: 10.1002/Ange.201802416 |
0.707 |
|
2018 |
Kalbermatter D, Shrestha N, Ader-Ebert N, Herren M, Moll P, Plemper RK, Altmann KH, Langedijk JP, Gall F, Lindenmann U, Riedl R, Fotiadis D, Plattet P. Primary Resistance Mechanism of the Canine Distemper Virus Fusion Protein against a Small-Molecule Membrane Fusion Inhibitor. Virus Research. PMID 30296457 DOI: 10.1016/J.Virusres.2018.10.003 |
0.731 |
|
2018 |
Agnello S, Brand M, Chellat MF, Gazzola S, Riedl R. A Structural View on Medicinal Chemistry Strategies against Drug Resistance. Angewandte Chemie (International Ed. in English). PMID 29846032 DOI: 10.1002/Anie.201802416 |
0.745 |
|
2017 |
Fischer T, Riedl R. Development of a Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-7/-13 Inhibitor. Molecules (Basel, Switzerland). 22. PMID 32961647 DOI: 10.3390/Molecules22091548 |
0.482 |
|
2017 |
Senn N, Ott M, Lanz J, Riedl R. Targeted Polypharmacology: Discovery of a Highly Potent Non-Hydroxamate Dual Matrix Metalloproteinase (MMP)-10/-13 Inhibitor. Journal of Medicinal Chemistry. PMID 28953404 DOI: 10.1021/Acs.Jmedchem.7B01001 |
0.753 |
|
2017 |
Chellat MF, Riedl R. Pseudouridimycin: the first Nucleoside Analogue that Selectively Inhibits Bacterial RNA Polymerase. Angewandte Chemie (International Ed. in English). PMID 28895263 DOI: 10.1002/Anie.201708133 |
0.771 |
|
2017 |
Fischer T, Riedl R. Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor. Chemistryopen. 6: 192-195. PMID 28413749 DOI: 10.1002/Open.201600158 |
0.533 |
|
2017 |
Fischer T, Riedl R. Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor. Chemistryopen. 6: 167. PMID 28413746 DOI: 10.1002/open.201700042 |
0.463 |
|
2017 |
Eid SA, Adams M, Scherer T, Torres-Gómez H, Hackl MT, Kaplanian M, Riedl R, Luger A, Fürnsinn C. Emodin, a compound with putative antidiabetic potential, deteriorates glucose tolerance in rodents. European Journal of Pharmacology. PMID 28108376 DOI: 10.1016/J.Ejphar.2017.01.022 |
0.732 |
|
2017 |
Fischer T, Riedl R. Cover profile : targeted fluoro positioning for the discovery of a potent and highly selective matrix metalloproteinase inhibitor Chemistryopen. 6: 167. DOI: 10.21256/Zhaw-1688 |
0.507 |
|
2017 |
Fischer T, Riedl R. Cover Picture: Targeted Fluoro Positioning for the Discovery of a Potent and Highly Selective Matrix Metalloproteinase Inhibitor (ChemistryOpen 2/2017) Chemistryopen. 6: 165-165. DOI: 10.1002/Open.201700043 |
0.508 |
|
2017 |
Chellat MF, Riedl R. Pseudouridimycin: das erste Nukleosid-Analogon, das bakterielle RNA-Polymerase selektiv inhibiert Angewandte Chemie. 129: 13364-13366. DOI: 10.1002/Ange.201708133 |
0.737 |
|
2016 |
Chellat MF, Raguž L, Riedl R. Targeting Antibiotic Resistance. Angewandte Chemie (International Ed. in English). PMID 27000559 DOI: 10.1002/Anie.201506818 |
0.742 |
|
2016 |
Fischer T, Riedl R. Molecular Recognition of the Catalytic Zinc(II) Ion in MMP-13: Structure-Based Evolution of an Allosteric Inhibitor to Dual Binding Mode Inhibitors with Improved Lipophilic Ligand Efficiencies. International Journal of Molecular Sciences. 17. PMID 26938528 DOI: 10.3390/Ijms17030314 |
0.51 |
|
2016 |
Chellat MF, Raguž L, Riedl R. Antibiotikaresistenzen gezielt überwinden Angewandte Chemie. 128: 6710-6738. DOI: 10.1002/Ange.201506818 |
0.759 |
|
2015 |
Lanz J, Riedl R. Merging allosteric and active site binding motifs: de novo generation of target selectivity and potency via natural-product-derived fragments. Chemmedchem. 10: 451-4. PMID 25487909 DOI: 10.1002/Cmdc.201402478 |
0.691 |
|
2015 |
Lanz J, Riedl R. Cover Picture: Merging Allosteric and Active Site Binding Motifs: De novo Generation of Target Selectivity and Potency via Natural-Product-Derived Fragments (ChemMedChem 3/2015) Chemmedchem. 10: 425-425. DOI: 10.1002/Cmdc.201590003 |
0.671 |
|
2013 |
Fischer T, Riedl R. Strategic targeting of multiple water-mediated interactions: a concise and rational structure-based design approach to potent and selective MMP-13 inhibitors. Chemmedchem. 8: 1457-61, 1572. PMID 23894097 DOI: 10.1002/Cmdc.201300278 |
0.467 |
|
2013 |
Fischer T, Riedl R. Back Cover: Strategic Targeting of Multiple Water‐Mediated Interactions: A Concise and Rational Structure‐Based Design Approach to Potent and Selective MMP‐13 Inhibitors (ChemMedChem 9/2013) Chemmedchem. 8: 1572-1572. DOI: 10.1002/Cmdc.201390039 |
0.494 |
|
2012 |
Höck S, Riedl R. chemf: A purely functional chemistry toolkit. Journal of Cheminformatics. 4: 38. PMID 23253942 DOI: 10.1186/1758-2946-4-38 |
0.698 |
|
2002 |
Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer DE. Genomic effects of polyamide/DNA interactions on mRNA expression. Chemistry & Biology. 9: 821-7. PMID 12144926 DOI: 10.1016/S1074-5521(02)00174-6 |
0.745 |
|
2000 |
Berkessel A, Riedl R. Combinatorial de novo synthesis of catalysts: how much of a hit-structure is needed for activity? Journal of Combinatorial Chemistry. 2: 215-9. PMID 10827924 DOI: 10.1021/Cc990073I |
0.495 |
|
1998 |
Riedl R, Tappe R, Berkessel A. Probing the scope of the asymmetric dihydroxylation of polymer-bound olefins. Monitoring of HRMAS NMR allows for reaction control and on-bead measurement of enantiomeric excess Journal of the American Chemical Society. 120: 8994-9000. DOI: 10.1021/Ja980183D |
0.475 |
|
1997 |
Berkessel A, Riedl R. Fluorescence Reporters for Phosphodiesterase Activity Angewandte Chemie (International Edition in English). 36: 1481-1483. DOI: 10.1002/Anie.199714811 |
0.478 |
|
1997 |
Berkessel A, Riedl R. Fluoreszenz-Reporter für Phosphodiesterase-Aktivität Angewandte Chemie. 109: 1518-1520. DOI: 10.1002/Ange.19971091313 |
0.468 |
|
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