Rudi D'Hooge - Publications

Affiliations: 
KUL 

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Domínguez-Iturza N, Lo AC, Shah D, Armendáriz M, Vannelli A, Mercaldo V, Trusel M, Li KW, Gastaldo D, Santos AR, Callaerts-Vegh Z, D'Hooge R, Mameli M, Van der Linden A, Smit AB, et al. The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour. Nature Communications. 10: 3454. PMID 31371726 DOI: 10.1038/s41467-019-11203-y  0.6
2019 Thonnard D, Callaerts-Vegh Z, D'Hooge R. Differential effects of post-training scopolamine on spatial and non-spatial learning tasks in mice. Brain Research Bulletin. 152: 52-62. PMID 31302239 DOI: 10.1016/j.brainresbull.2019.07.012  0.56
2019 Lima KR, de Vargas LDS, Ramborger B, Roehrs R, Sevenster D, Izquierdo I, D'Hooge R, Mello-Carpes PB. NORADRENERGIC AND DOPAMINERGIC INVOLVEMENT IN NOVELTY MODULATION OF AVERSIVE MEMORY GENERALIZATION OF ADULT RATS. Behavioural Brain Research. 111991. PMID 31150747 DOI: 10.1016/j.bbr.2019.111991  0.68
2019 Van den Broeck L, Hansquine P, Callaerts-Vegh Z, D'Hooge R. Impaired Reversal Learning in APPPS1-21 Mice in the Touchscreen Visual Discrimination Task. Frontiers in Behavioral Neuroscience. 13: 92. PMID 31143103 DOI: 10.3389/fnbeh.2019.00092  0.56
2019 Thonnard D, Dreesen E, Callaerts-Vegh Z, D'Hooge R. NMDA receptor dependence of reversal learning and the flexible use of cognitively demanding search strategies in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90: 235-244. PMID 30529376 DOI: 10.1016/j.pnpbp.2018.12.003  0.56
2018 Shah D, Verhoye M, Van der Linden A, D'Hooge R. Acquisition of Spatial Search Strategies and Reversal Learning in the Morris Water Maze Depend on Disparate Brain Functional Connectivity in Mice. Cerebral Cortex (New York, N.Y. : 1991). PMID 30590460 DOI: 10.1093/cercor/bhy329  0.6
2018 da Silva de Vargas L, Sevenster D, Lima K, Izquierdo I, D'Hooge R, Mello-Carpes PB. NOVELTY EXPOSURE HINDERS AVERSIVE MEMORY GENERALIZATION AND DEPENDS ON HIPPOCAMPAL PROTEIN SYNTHESIS. Behavioural Brain Research. PMID 30367969 DOI: 10.1016/j.bbr.2018.10.034  0.68
2018 Salas IH, Callaerts-Vegh Z, D'Hooge R, Saido TC, Dotti CG, De Strooper B. Increased Insoluble Amyloid-β Induces Negligible Cognitive Deficits in Old AppNL/NL Knock-In Mice. Journal of Alzheimer's Disease : Jad. PMID 30320577 DOI: 10.3233/JAD-180410  0.56
2018 Sierksma A, Lu A, Salta E, Vanden Eynden E, Callaerts-Vegh Z, D'Hooge R, Blum D, Buée L, Fiers M, De Strooper B. Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology. Molecular Neurodegeneration. 13: 54. PMID 30314521 DOI: 10.1186/s13024-018-0285-1  0.6
2018 Sevenster D, Visser RM, D'Hooge R. A translational perspective on neural circuits of fear extinction: current promises and challenges. Neurobiology of Learning and Memory. PMID 29981423 DOI: 10.1016/j.nlm.2018.07.002  0.68
2018 Stroobants S, Wolf H, Callaerts-Vegh Z, Dierks T, Lübke T, D'Hooge R. Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. Frontiers in Behavioral Neuroscience. 12: 69. PMID 29706874 DOI: 10.3389/fnbeh.2018.00069  0.56
2018 Maes E, Krypotos AM, Boddez Y, Alfei Palloni JM, D'Hooge R, De Houwer J, Beckers T. Failures to replicate blocking are surprising and informative-Reply to Soto (2018). Journal of Experimental Psychology. General. 147: 603-610. PMID 29698031 DOI: 10.1037/xge0000413  1
2018 Van der Jeugd A, Parra-Damas A, Baeta-Corral R, Soto-Faguás CM, Ahmed T, LaFerla FM, Giménez-Llort L, D'Hooge R, Saura CA. Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice. Scientific Reports. 8: 6431. PMID 29691439 DOI: 10.1038/s41598-018-24741-0  0.52
2018 Shah D, Latif-Hernandez A, De Strooper B, Saito T, Saido T, Verhoye M, D'Hooge R, Van der Linden A. Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APP knock-in mice. Scientific Reports. 8: 6264. PMID 29674739 DOI: 10.1038/s41598-018-24657-9  0.6
2018 Van der Jeugd A, D'Hooge R. Assessment of Social Transmission of Food Preferences Behaviors. Journal of Visualized Experiments : Jove. PMID 29443064 DOI: 10.3791/57029  0.52
2018 Salas IH, Weerasekera A, Ahmed T, Callaerts-Vegh Z, Himmelreich U, D'Hooge R, Balschun D, Saido TC, De Strooper B, Dotti CG. High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease. Neurobiology of Disease. PMID 29427755 DOI: 10.1016/j.nbd.2018.02.001  0.6
2017 Sevenster D, Haesen K, Vervliet B, Kindt M, D'Hooge R. Prevention and treatment strategies for contextual overgeneralization. Scientific Reports. 7: 16967. PMID 29208913 DOI: 10.1038/s41598-017-16893-2  0.68
2017 van Boxelaere M, Clements J, Callaerts P, D'Hooge R, Callaerts-Vegh Z. Unpredictable chronic mild stress differentially impairs social and contextual discrimination learning in two inbred mouse strains. Plos One. 12: e0188537. PMID 29166674 DOI: 10.1371/journal.pone.0188537  0.56
2017 Hernandez AL, Shah D, Craessaerts K, Saido T, Saito T, De Strooper B, Van der Linden A, D'Hooge R. Subtle behavioral changes and increased prefrontal-hippocampal network synchronicity in APP(NL-G-F) mice before prominent plaque deposition. Behavioural Brain Research. PMID 29158112 DOI: 10.1016/j.bbr.2017.11.017  0.6
2017 Salas IH, Callaerts-Vegh Z, Arranz AM, Guix FX, D'Hooge R, Esteban JA, De Strooper B, Dotti CG. Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity. Plos One. 12: e0187179. PMID 29065158 DOI: 10.1371/journal.pone.0187179  0.56
2017 Maes E, Vanderoost E, D'Hooge R, De Houwer J, Beckers T. Individual Difference Factors in the Learning and Transfer of Patterning Discriminations. Frontiers in Psychology. 8: 1262. PMID 28804468 DOI: 10.3389/fpsyg.2017.01262  1
2017 Stroobants S, Damme M, der Jeugd AV, Vermaercke B, Andersson C, Fogh J, Saftig P, Blanz J, D'Hooge R. Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice. Neurobiology of Disease. PMID 28720484 DOI: 10.1016/j.nbd.2017.07.013  0.32
2017 Salas IH, Callaerts-Vegh Z, Arranz AM, Guix FX, D'Hooge R, Esteban JA, De Strooper B, Dotti CG. Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity. Plos One. 12: e0178016. PMID 28686613 DOI: 10.1371/journal.pone.0178016  0.56
2017 Pooters T, Laeremans A, Gantois I, Vermaercke B, Arckens L, D'Hooge R. Comparison of the spatial-cognitive functions of dorsomedial striatum and anterior cingulate cortex in mice. Plos One. 12: e0176295. PMID 28467439 DOI: 10.1371/journal.pone.0176295  0.32
2017 Salas IH, Callaerts-Vegh Z, Arranz AM, Guix FX, D'Hooge R, Esteban JA, De Strooper B, Dotti CG. Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity. Plos One. 12: e0171968. PMID 28207852 DOI: 10.1371/journal.pone.0171968  0.56
2016 Latif-Hernandez A, Shah D, Ahmed T, Lo AC, Callaerts-Vegh Z, Van der Linden A, Balschun D, D'Hooge R. Quinolinic acid injection in mouse medial prefrontal cortex affects reversal learning abilities, cortical connectivity and hippocampal synaptic plasticity. Scientific Reports. 6: 36489. PMID 27819338 DOI: 10.1038/srep36489  0.6
2016 Maes E, Boddez Y, Alfei JM, Krypotos AM, D'Hooge R, De Houwer J, Beckers T. The Elusive Nature of the Blocking Effect: 15 Failures to Replicate. Journal of Experimental Psychology. General. PMID 27428670 DOI: 10.1037/xge0000200  1
2016 Verreet T, Rangarajan JR, Quintens R, Verslegers M, Lo AC, Govaerts K, Neefs M, Leysen L, Baatout S, Maes F, Himmelreich U, D'Hooge R, Moons L, Benotmane MA. Persistent Impact of In utero Irradiation on Mouse Brain Structure and Function Characterized by MR Imaging and Behavioral Analysis. Frontiers in Behavioral Neuroscience. 10: 83. PMID 27199692 DOI: 10.3389/fnbeh.2016.00083  0.68
2016 Shah D, Praet J, Latif Hernandez A, Höfling C, Anckaerts C, Bard F, Morawski M, Detrez JR, Prinsen E, Villa A, De Vos WH, Maggi A, D'Hooge R, Balschun D, Rossner S, et al. Soluble amyloid induces hypersynchrony of BOLD resting-state networks in transgenic mice and provides an early therapeutic window before amyloid plaque deposition. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27107518 DOI: 10.1016/j.jalz.2016.03.010  0.6
2015 Pooters T, Gantois I, Vermaercke B, D'Hooge R. Inability to acquire spatial information and deploy spatial search strategies in mice with lesions in dorsomedial striatum. Behavioural Brain Research. PMID 26548360 DOI: 10.1016/j.bbr.2015.11.001  0.68
2015 Huang Y, Skwarek-Maruszewska A, Horré K, Vandewyer E, Wolfs L, Snellinx A, Saito T, Radaelli E, Corthout N, Colombelli J, Lo AC, Van Aerschot L, Callaerts-Vegh Z, Trabzuni D, Bossers K, et al. Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models. Science Translational Medicine. 7: 309ra164. PMID 26468326 DOI: 10.1126/scitranslmed.aab3492  0.68
2015 Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L, Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, et al. Brain endothelial TAK1 and NEMO safeguard the neurovascular unit. The Journal of Experimental Medicine. 212: 1529-49. PMID 26347470 DOI: 10.1084/jem.20150165  0.68
2015 Callaerts-Vegh Z, Ahmed T, Vermaercke B, Marynen P, Balschun D, Froyen G, D'Hooge R. Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice. Frontiers in Behavioral Neuroscience. 9: 179. PMID 26217206 DOI: 10.3389/fnbeh.2015.00179  0.68
2015 Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Malik E, Mariciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D'Hooge R, Sergeant N, et al. A2A adenosine receptor deletion is protective in a mouse model of Tauopathy. Molecular Psychiatry. PMID 26216297 DOI: 10.1038/mp.2015.115  0.6
2015 Maes E, De Filippo G, Inkster AB, Lea SE, De Houwer J, D'Hooge R, Beckers T, Wills AJ. Feature- versus rule-based generalization in rats, pigeons and humans. Animal Cognition. PMID 26188712 DOI: 10.1007/s10071-015-0895-8  0.4
2015 Pasciuto E, Ahmed T, Wahle T, Gardoni F, D'Andrea L, Pacini L, Jacquemont S, Tassone F, Balschun D, Dotti CG, Callaerts-Vegh Z, D'Hooge R, Müller UC, Di Luca M, De Strooper B, et al. Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome. Neuron. 87: 382-98. PMID 26182420 DOI: 10.1016/j.neuron.2015.06.032  0.68
2015 Goddyn H, Callaerts-Vegh Z, D'Hooge R. Functional Dissociation of Group III Metabotropic Glutamate Receptors Revealed by Direct Comparison between the Behavioral Profiles of Knockout Mouse Lines. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25999589 DOI: 10.1093/ijnp/pyv053  0.56
2015 Bollen E, Akkerman S, Puzzo D, Gulisano W, Palmeri A, D'Hooge R, Balschun D, Steinbusch HW, Blokland A, Prickaerts J. Object memory enhancement by combining sub-efficacious doses of specific phosphodiesterase inhibitors. Neuropharmacology. 95: 361-6. PMID 25896769 DOI: 10.1016/j.neuropharm.2015.04.008  0.68
2015 Stein A, Stroobants S, Gieselmann V, D'Hooge R, Matzner U. Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic Leukodystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1160-8. PMID 25896249 DOI: 10.1038/mt.2015.69  0.68
2015 Pooters T, Van der Jeugd A, Callaerts-Vegh Z, D'Hooge R. Telencephalic neurocircuitry and synaptic plasticity in rodent spatial learning and memory. Brain Research. PMID 25619550 DOI: 10.1016/j.brainres.2015.01.015  0.68
2015 Van der Perren A, Toelen J, Casteels C, Macchi F, Van Rompuy AS, Sarre S, Casadei N, Nuber S, Himmelreich U, Osorio Garcia MI, Michotte Y, D'Hooge R, Bormans G, Van Laere K, Gijsbers R, et al. Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors. Neurobiology of Aging. 36: 1543-58. PMID 25599874 DOI: 10.1016/j.neurobiolaging.2014.11.015  0.68
2015 Bollen B, Ramanantsoa N, Naert A, Matrot B, Van den Bergh O, D'Hooge R, Gallego J. Emotional disorders in adult mice heterozygous for the transcription factor Phox2b. Physiology & Behavior. 141: 120-6. PMID 25582512 DOI: 10.1016/j.physbeh.2015.01.012  0.68
2015 Dionísio PA, Amaral JD, Ribeiro MF, Lo AC, D'Hooge R, Rodrigues CM. Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset. Neurobiology of Aging. 36: 228-40. PMID 25443293 DOI: 10.1016/j.neurobiolaging.2014.08.034  0.68
2015 Ahmed T, Blum D, Burnouf S, Demeyer D, Buée-Scherrer V, D'Hooge R, Buée L, Balschun D. Rescue of impaired late-phase long-term depression in a tau transgenic mouse model. Neurobiology of Aging. 36: 730-9. PMID 25443285 DOI: 10.1016/j.neurobiolaging.2014.09.015  0.68
2015 Woolley DG, Mantini D, Coxon JP, D'Hooge R, Swinnen SP, Wenderoth N. Virtual water maze learning in human increases functional connectivity between posterior hippocampus and dorsal caudate. Human Brain Mapping. 36: 1265-77. PMID 25418860 DOI: 10.1002/hbm.22700  0.68
2015 Trovò L, Stroobants S, D'Hooge R, Ledesma MD, Dotti CG. Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKS. Neurobiology of Disease. 73: 319-26. PMID 25251606 DOI: 10.1016/j.nbd.2014.09.008  0.68
2015 Verslegers M, Van Hove I, Dekeyster E, Gantois I, Hu TT, D'Hooge R, Arckens L, Moons L. MMP-2 mediates Purkinje cell morphogenesis and spine development in the mouse cerebellum. Brain Structure & Function. 220: 1601-17. PMID 24652381 DOI: 10.1007/s00429-014-0747-3  0.68
2015 Laeremans A, Sabanov V, Ahmed T, Nys J, Van de Plas B, Vinken K, Woolley DG, Gantois I, D'Hooge R, Arckens L, Balschun D. Distinct and simultaneously active plasticity mechanisms in mouse hippocampus during different phases of Morris water maze training. Brain Structure & Function. 220: 1273-90. PMID 24562414 DOI: 10.1007/s00429-014-0722-z  0.68
2015 Pasciuto E, Ahmed T, Wahle T, Gardoni F, D'Andrea L, Pacini L, Jacquemont S, Tassone F, Balschun D, Dotti CG, Callaerts-Vegh Z, D'Hooge R, Müller UC, Di Luca M, De Strooper B, et al. Errata to Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to SynapticDeficits in Fragile X Syndrome [Neuron, 87, (2015), 382-398] Neuron. 87: 908. DOI: 10.1016/j.neuron.2015.08.010  0.68
2014 Laurent C, Burnouf S, Ferry B, Batalha VL, Coelho JE, Baqi Y, Malik E, Mariciniak E, Parrot S, Van der Jeugd A, Faivre E, Flaten V, Ledent C, D'Hooge R, Sergeant N, et al. A2A adenosine receptor deletion is protective in a mouse model of Tauopathy. Molecular Psychiatry. PMID 25450226 DOI: 10.1038/mp.2014.151  0.68
2014 Papadopoulou AS, Serneels L, Achsel T, Mandemakers W, Callaerts-Vegh Z, Dooley J, Lau P, Ayoubi T, Radaelli E, Spinazzi M, Neumann M, Hébert SS, Silahtaroglu A, Liston A, D'Hooge R, et al. Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice. Neurobiology of Disease. 73: 275-288. PMID 25315682 DOI: 10.1016/j.nbd.2014.10.006  0.68
2014 Ahmed T, Van der Jeugd A, Blum D, Galas MC, D'Hooge R, Buee L, Balschun D. Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion. Neurobiology of Aging. 35: 2474-8. PMID 24913895 DOI: 10.1016/j.neurobiolaging.2014.05.005  0.68
2014 Lo AC, De Maeyer JH, Vermaercke B, Callaerts-Vegh Z, Schuurkes JA, D'Hooge R. SSP-002392, a new 5-HT4 receptor agonist, dose-dependently reverses scopolamine-induced learning and memory impairments in C57Bl/6 mice. Neuropharmacology. 85: 178-89. PMID 24863046 DOI: 10.1016/j.neuropharm.2014.05.013  0.68
2014 Bollen E, Puzzo D, Rutten K, Privitera L, De Vry J, Vanmierlo T, Kenis G, Palmeri A, D'Hooge R, Balschun D, Steinbusch HM, Blokland A, Prickaerts J. Improved long-term memory via enhancing cGMP-PKG signaling requires cAMP-PKA signaling. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2497-505. PMID 24813825 DOI: 10.1038/npp.2014.106  0.68
2014 Piccart E, De Backer JF, Gall D, Lambot L, Raes A, Vanhoof G, Schiffmann S, D'Hooge R. Genetic deletion of PDE10A selectively impairs incentive salience attribution and decreases medium spiny neuron excitability. Behavioural Brain Research. 268: 48-54. PMID 24698799 DOI: 10.1016/j.bbr.2014.03.016  0.68
2014 Vermaercke B, Cop E, Willems S, D'Hooge R, Op de Beeck HP. More complex brains are not always better: rats outperform humans in implicit category-based generalization by implementing a similarity-based strategy. Psychonomic Bulletin & Review. 21: 1080-6. PMID 24408657 DOI: 10.3758/s13423-013-0579-9  0.68
2013 Oliveras-Salvá M, Van der Perren A, Casadei N, Stroobants S, Nuber S, D'Hooge R, Van den Haute C, Baekelandt V. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration. Molecular Neurodegeneration. 8: 44. PMID 24267638 DOI: 10.1186/1750-1326-8-44  0.68
2013 Lo AC, Tesseur I, Scopes DI, Nerou E, Callaerts-Vegh Z, Vermaercke B, Treherne JM, De Strooper B, D'Hooge R. Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500. Neuropharmacology. 75: 458-66. PMID 24035915 DOI: 10.1016/j.neuropharm.2013.08.030  0.68
2013 Piccart E, Langlois X, Vanhoof G, D'Hooge R. Selective inhibition of phosphodiesterase 10A impairs appetitive and aversive conditioning and incentive salience attribution. Neuropharmacology. 75: 437-44. PMID 23973318 DOI: 10.1016/j.neuropharm.2013.08.006  0.68
2013 Van der Jeugd A, Vermaercke B, Derisbourg M, Lo AC, Hamdane M, Blum D, Buée L, D'Hooge R. Progressive age-related cognitive decline in tau mice. Journal of Alzheimer's Disease : Jad. 37: 777-88. PMID 23948912 DOI: 10.3233/JAD-130110  0.68
2013 Prox J, Bernreuther C, Altmeppen H, Grendel J, Glatzel M, D'Hooge R, Stroobants S, Ahmed T, Balschun D, Willem M, Lammich S, Isbrandt D, Schweizer M, Horré K, De Strooper B, et al. Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12915-28, 12928a. PMID 23926248 DOI: 10.1523/JNEUROSCI.5910-12.2013  0.68
2013 Lo AC, Iscru E, Blum D, Tesseur I, Callaerts-Vegh Z, Buée L, De Strooper B, Balschun D, D'Hooge R. Amyloid and tau neuropathology differentially affect prefrontal synaptic plasticity and cognitive performance in mouse models of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 37: 109-25. PMID 23788007 DOI: 10.3233/JAD-122296  0.68
2013 Iscru E, Goddyn H, Ahmed T, Callaerts-Vegh Z, D'Hooge R, Balschun D. Improved spatial learning is associated with increased hippocampal but not prefrontal long-term potentiation in mGluR4 knockout mice. Genes, Brain, and Behavior. 12: 615-25. PMID 23714430 DOI: 10.1111/gbb.12052  0.68
2013 Tesseur I, Lo AC, Roberfroid A, Dietvorst S, Van Broeck B, Borgers M, Gijsen H, Moechars D, Mercken M, Kemp J, D'Hooge R, De Strooper B. Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models". Science (New York, N.Y.). 340: 924-e. PMID 23704554 DOI: 10.1126/science.1233937  0.68
2013 Vanmarsenille L, Verbeeck J, Belet S, Roebroek AJ, Van de Putte T, Nevelsteen J, Callaerts-Vegh Z, D'Hooge R, Marynen P, Froyen G. Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability. Plos One. 8: e64144. PMID 23675524 DOI: 10.1371/journal.pone.0064144  0.68
2013 Simões AE, Pereira DM, Amaral JD, Nunes AF, Gomes SE, Rodrigues PM, Lo AC, D'Hooge R, Steer CJ, Thibodeau SN, Borralho PM, Rodrigues CM. Efficient recovery of proteins from multiple source samples after TRIzol(®) or TRIzol(®)LS RNA extraction and long-term storage. Bmc Genomics. 14: 181. PMID 23496794 DOI: 10.1186/1471-2164-14-181  0.68
2013 Tesseur I, Pimenova AA, Lo AC, Ciesielska M, Lichtenthaler SF, De Maeyer JH, Schuurkes JA, D'Hooge R, De Strooper B. Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice. Neurobiology of Aging. 34: 1779-89. PMID 23474291 DOI: 10.1016/j.neurobiolaging.2013.01.020  0.68
2013 Trovò L, Ahmed T, Callaerts-Vegh Z, Buzzi A, Bagni C, Chuah M, Vandendriessche T, D'Hooge R, Balschun D, Dotti CG. Low hippocampal PI(4,5)Pâ‚‚ contributes to reduced cognition in old mice as a result of loss of MARCKS. Nature Neuroscience. 16: 449-55. PMID 23434911 DOI: 10.1038/nn.3342  0.68
2013 Callaerts-Vegh Z, Moechars D, Van Acker N, Daneels G, Goris I, Leo S, Naert A, Meert T, Balschun D, D'Hooge R. Haploinsufficiency of VGluT1 but not VGluT2 impairs extinction of spatial preference and response suppression. Behavioural Brain Research. 245: 13-21. PMID 23396167 DOI: 10.1016/j.bbr.2013.01.042  0.68
2013 Woolley DG, Laeremans A, Gantois I, Mantini D, Vermaercke B, Op de Beeck HP, Swinnen SP, Wenderoth N, Arckens L, D'Hooge R. Homologous involvement of striatum and prefrontal cortex in rodent and human water maze learning. Proceedings of the National Academy of Sciences of the United States of America. 110: 3131-6. PMID 23382228 DOI: 10.1073/pnas.1217832110  0.68
2013 Naert A, Gantois I, Laeremans A, Vreysen S, Van den Bergh G, Arckens L, Callaerts-Vegh Z, D'Hooge R. Behavioural alterations relevant to developmental brain disorders in mice with neonatally induced ventral hippocampal lesions. Brain Research Bulletin. 94: 71-81. PMID 23357176 DOI: 10.1016/j.brainresbull.2013.01.008  0.68
2013 Van der Jeugd A, Blum D, Raison S, Eddarkaoui S, Buée L, D'Hooge R. Observations in THY-Tau22 mice that resemble behavioral and psychological signs and symptoms of dementia. Behavioural Brain Research. 242: 34-9. PMID 23247080 DOI: 10.1016/j.bbr.2012.12.008  0.68
2013 Stroobants S, Gantois I, Pooters T, D'Hooge R. Increased gait variability in mice with small cerebellar cortex lesions and normal rotarod performance. Behavioural Brain Research. 241: 32-7. PMID 23219967 DOI: 10.1016/j.bbr.2012.11.034  0.68
2013 Nuytens K, Gantois I, Stijnen P, Iscru E, Laeremans A, Serneels L, Van Eylen L, Liebhaber SA, Devriendt K, Balschun D, Arckens L, Creemers JW, D'Hooge R. Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice. Neurobiology of Disease. 51: 144-51. PMID 23153818 DOI: 10.1016/j.nbd.2012.11.004  0.68
2013 Gantois I, Pop AS, de Esch CE, Buijsen RA, Pooters T, Gomez-Mancilla B, Gasparini F, Oostra BA, D'Hooge R, Willemsen R. Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice. Behavioural Brain Research. 239: 72-9. PMID 23142366 DOI: 10.1016/j.bbr.2012.10.059  0.68
2013 Iscru E, Ahmed T, Coremans V, Bozzi Y, Caleo M, Conway EM, D'Hooge R, Balschun D. Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region. Neuroscience. 231: 413-9. PMID 23123921 DOI: 10.1016/j.neuroscience.2012.10.049  0.68
2013 Lo AC, Callaerts-Vegh Z, Nunes AF, Rodrigues CM, D'Hooge R. Tauroursodeoxycholic acid (TUDCA) supplementation prevents cognitive impairment and amyloid deposition in APP/PS1 mice. Neurobiology of Disease. 50: 21-9. PMID 22974733 DOI: 10.1016/j.nbd.2012.09.003  0.68
2013 Ramalho RM, Nunes AF, Dias RB, Amaral JD, Lo AC, D'Hooge R, Sebastião AM, Rodrigues CM. Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice. Neurobiology of Aging. 34: 551-61. PMID 22621777 DOI: 10.1016/j.neurobiolaging.2012.04.018  0.68
2013 Laeremans A, Nys J, Luyten W, D'Hooge R, Paulussen M, Arckens L. AMIGO2 mRNA expression in hippocampal CA2 and CA3a. Brain Structure & Function. 218: 123-30. PMID 22314660 DOI: 10.1007/s00429-012-0387-4  0.68
2012 Callaerts-Vegh Z, Leo S, Vermaercke B, Meert T, D'Hooge R. LPA5 receptor plays a role in pain sensitivity, emotional exploration and reversal learning. Genes, Brain, and Behavior. 11: 1009-19. PMID 23039190 DOI: 10.1111/j.1601-183X.2012.00840.x  0.68
2012 Boddez Y, Callaerts-Vegh Z, Vervliet B, Baeyens F, D'Hooge R, Hermans D, Beckers T. Stimulus generalization and return of fear in C57BL/6J mice. Frontiers in Behavioral Neuroscience. 6: 41. PMID 22811661 DOI: 10.3389/fnbeh.2012.00041  0.68
2012 Kowalewski B, Lamanna WC, Lawrence R, Damme M, Stroobants S, Padva M, Kalus I, Frese MA, Lübke T, Lüllmann-Rauch R, D'Hooge R, Esko JD, Dierks T. Arylsulfatase G inactivation causes loss of heparan sulfate 3-O-sulfatase activity and mucopolysaccharidosis in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 10310-5. PMID 22689975 DOI: 10.1073/pnas.1202071109  0.68
2012 Van der Jeugd A, Hochgräfe K, Ahmed T, Decker JM, Sydow A, Hofmann A, Wu D, Messing L, Balschun D, D'Hooge R, Mandelkow EM. Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau. Acta Neuropathologica. 123: 787-805. PMID 22532069 DOI: 10.1007/s00401-012-0987-3  0.68
2012 Nunes AF, Amaral JD, Lo AC, Fonseca MB, Viana RJ, Callaerts-Vegh Z, D'Hooge R, Rodrigues CM. TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice. Molecular Neurobiology. 45: 440-54. PMID 22438081 DOI: 10.1007/s12035-012-8256-y  0.68
2012 Matthes F, Stroobants S, Gerlach D, Wohlenberg C, Wessig C, Fogh J, Gieselmann V, Eckhardt M, D'Hooge R, Matzner U. Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age. Human Molecular Genetics. 21: 2599-609. PMID 22388935 DOI: 10.1093/hmg/dds086  0.68
2012 Bollen B, Matrot B, Ramanantsoa N, Van den Bergh O, D'Hooge R, Gallego J. Olfactory classical conditioning in neonatal mouse pups using thermal stimuli. Behavioural Brain Research. 229: 250-6. PMID 22257564 DOI: 10.1016/j.bbr.2011.12.030  0.68
2012 Van Hove I, Verslegers M, Buyens T, Delorme N, Lemmens K, Stroobants S, Gantois I, D'Hooge R, Moons L. An aberrant cerebellar development in mice lacking matrix metalloproteinase-3. Molecular Neurobiology. 45: 17-29. PMID 22108898 DOI: 10.1007/s12035-011-8215-z  0.68
2011 Wallays G, Nuyens D, Silasi-Mansat R, Souffreau J, Callaerts-Vegh Z, Van Nuffelen A, Moons L, D'Hooge R, Lupu F, Carmeliet P, Collen D, Dewerchin M. Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2881-8. PMID 21940951 DOI: 10.1161/ATVBAHA.111.237859  0.68
2011 Sydow A, Van der Jeugd A, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Reversibility of Tau-related cognitive defects in a regulatable FTD mouse model. Journal of Molecular Neuroscience : Mn. 45: 432-7. PMID 21822709 DOI: 10.1007/s12031-011-9604-5  0.68
2011 Naert A, Callaerts-Vegh Z, Moechars D, Meert T, D'Hooge R. Vglut2 haploinsufficiency enhances behavioral sensitivity to MK-801 and amphetamine in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1316-21. PMID 21514350 DOI: 10.1016/j.pnpbp.2011.03.023  0.68
2011 Ahmed T, Sabanov V, D'Hooge R, Balschun D. An N-methyl-D-aspartate-receptor dependent, late-phase long-term depression in middle-aged mice identifies no GluN2-subunit bias. Neuroscience. 185: 27-38. PMID 21504782 DOI: 10.1016/j.neuroscience.2011.04.006  0.68
2011 Naert A, Callaerts-Vegh Z, D'Hooge R. Nocturnal hyperactivity, increased social novelty preference and delayed extinction of fear responses in post-weaning socially isolated mice. Brain Research Bulletin. 85: 354-62. PMID 21501666 DOI: 10.1016/j.brainresbull.2011.03.027  0.68
2011 Faldini E, Stroobants S, Lüllmann-Rauch R, Eckhardt M, Gieselmann V, Balschun D, D'Hooge R. Telencephalic histopathology and changes in behavioural and neural plasticity in a murine model for metachromatic leukodystrophy. Behavioural Brain Research. 222: 309-14. PMID 21459117 DOI: 10.1016/j.bbr.2011.03.059  0.68
2011 Sydow A, Van der Jeugd A, Zheng F, Ahmed T, Balschun D, Petrova O, Drexler D, Zhou L, Rune G, Mandelkow E, D'Hooge R, Alzheimer C, Mandelkow EM. Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2511-25. PMID 21325519 DOI: 10.1523/JNEUROSCI.5245-10.2011  0.68
2011 Van der Jeugd A, Ahmed T, Burnouf S, Belarbi K, Hamdame M, Grosjean ME, Humez S, Balschun D, Blum D, Buée L, D'Hooge R. Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission. Neurobiology of Learning and Memory. 95: 296-304. PMID 21167950 DOI: 10.1016/j.nlm.2010.12.005  0.68
2011 Damme M, Stroobants S, Walkley SU, Lüllmann-Rauch R, D'Hooge R, Fogh J, Saftig P, Lübke T, Blanz J. Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in α-mannosidosis. Journal of Neuropathology and Experimental Neurology. 70: 83-94. PMID 21157375 DOI: 10.1097/NEN.0b013e31820428fa  0.68
2011 Piccart E, Gantois I, Laeremans A, de Hoogt R, Meert T, Vanhoof G, Arckens L, D'Hooge R. Impaired appetitively as well as aversively motivated behaviors and learning in PDE10A-deficient mice suggest a role for striatal signaling in evaluative salience attribution. Neurobiology of Learning and Memory. 95: 260-9. PMID 21130175 DOI: 10.1016/j.nlm.2010.11.018  0.68
2011 Kerkhof I, Vansteenwegen D, Beckers T, Dirikx T, Baeyens F, D'Hooge R, Hermans D. The role of negative affective valence in return of fear Psychology of Fear: New Research. 153-170.  0.68
2010 Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, et al. Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15052-66. PMID 21068311 DOI: 10.1523/JNEUROSCI.0477-10.2010  0.68
2010 Kuperstein I, Broersen K, Benilova I, Rozenski J, Jonckheere W, Debulpaep M, Vandersteen A, Segers-Nolten I, Van Der Werf K, Subramaniam V, Braeken D, Callewaert G, Bartic C, D'Hooge R, Martins IC, et al. Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. The Embo Journal. 29: 3408-20. PMID 20818335 DOI: 10.1038/emboj.2010.211  0.68
2010 Buée L, Troquier L, Burnouf S, Belarbi K, Van der Jeugd A, Ahmed T, Fernandez-Gomez F, Caillierez R, Grosjean ME, Begard S, Barbot B, Demeyer D, Obriot H, Brion I, Buée-Scherrer V, et al. From tau phosphorylation to tau aggregation: what about neuronal death? Biochemical Society Transactions. 38: 967-72. PMID 20658986 DOI: 10.1042/BST0380967  0.68
2010 Vervoort R, Ceulemans H, Van Aerschot L, D'Hooge R, David G. Genetic modification of the inner ear lateral semicircular canal phenotype of the Bmp4 haplo-insufficient mouse. Biochemical and Biophysical Research Communications. 394: 780-5. PMID 20233579 DOI: 10.1016/j.bbrc.2010.03.069  0.68
2010 Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, Hüve J, Kratzke M, Baltes J, Boening D, Böning D, Klingauf J, Schu P. AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. The Embo Journal. 29: 1318-30. PMID 20203623 DOI: 10.1038/emboj.2010.15  0.68
2010 Coremans V, Ahmed T, Balschun D, D'Hooge R, DeVriese A, Cremer J, Antonucci F, Moons M, Baekelandt V, Reumers V, Cremer H, Eisch A, Lagace D, Janssens T, Bozzi Y, et al. Impaired neurogenesis, learning and memory and low seizure threshold associated with loss of neural precursor cell survivin. Bmc Neuroscience. 11: 2. PMID 20051123 DOI: 10.1186/1471-2202-11-2  0.68
2010 Woolley DG, Vermaercke B, Op de Beeck H, Wagemans J, Gantois I, D'Hooge R, Swinnen SP, Wenderoth N. Sex differences in human virtual water maze performance: novel measures reveal the relative contribution of directional responding and spatial knowledge. Behavioural Brain Research. 208: 408-14. PMID 20035800 DOI: 10.1016/j.bbr.2009.12.019  0.68
2010 Leo S, D'Hooge R, Meert T. Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice. Behavioural Brain Research. 208: 149-57. PMID 19931571 DOI: 10.1016/j.bbr.2009.11.023  0.68
2010 Balschun D, Moechars D, Callaerts-Vegh Z, Vermaercke B, Van Acker N, Andries L, D'Hooge R. Vesicular glutamate transporter VGLUT1 has a role in hippocampal long-term potentiation and spatial reversal learning. Cerebral Cortex (New York, N.Y. : 1991). 20: 684-93. PMID 19574394 DOI: 10.1093/cercor/bhp133  0.68
2009 Kalus I, Salmen B, Viebahn C, von Figura K, Schmitz D, D'Hooge R, Dierks T. Differential involvement of the extracellular 6-O-endosulfatases Sulf1 and Sulf2 in brain development and neuronal and behavioural plasticity. Journal of Cellular and Molecular Medicine. 13: 4505-21. PMID 20394677 DOI: 10.1111/j.1582-4934.2008.00558.x  0.68
2009 Leroy T, Stroobants S, Aerts JM, D'Hooge R, Berckmans D. Automatic analysis of altered gait in arylsulphatase A-deficient mice in the open field. Behavior Research Methods. 41: 787-94. PMID 19587193 DOI: 10.3758/BRM.41.3.787  0.68
2009 Van Calsteren K, Hartmann D, Van Aerschot L, Verbesselt R, Van Bree R, D'Hooge R, Amant F. Vinblastine and doxorubicin administration to pregnant mice affects brain development and behaviour in the offspring. Neurotoxicology. 30: 647-57. PMID 19422850 DOI: 10.1016/j.neuro.2009.04.009  0.68
2009 Serneels L, Van Biervliet J, Craessaerts K, Dejaegere T, Horré K, Van Houtvin T, Esselmann H, Paul S, Schäfer MK, Berezovska O, Hyman BT, Sprangers B, Sciot R, Moons L, Jucker M, et al. gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease. Science (New York, N.Y.). 324: 639-42. PMID 19299585 DOI: 10.1126/science.1171176  0.68
2009 Bollen B, Bouslama M, Matrot B, Rotrou Y, Vardon G, Lofaso F, Van den Bergh O, D'Hooge R, Gallego J. Cold stimulates the behavioral response to hypoxia in newborn mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R1503-11. PMID 19297539 DOI: 10.1152/ajpregu.90582.2008  0.68
2009 Kollmann K, Damme M, Deuschl F, Kahle J, D'Hooge R, Lüllmann-Rauch R, Lübke T. Molecular characterization and gene disruption of mouse lysosomal putative serine carboxypeptidase 1. The Febs Journal. 276: 1356-69. PMID 19187242 DOI: 10.1111/j.1742-4658.2009.06877.x  0.68
2009 Leroy T, Silva M, D'Hooge R, Aerts JM, Berckmans D. Automated gait analysis in the open-field test for laboratory mice. Behavior Research Methods. 41: 148-53. PMID 19182134 DOI: 10.3758/BRM.41.1.148  0.68
2009 Matzner U, Lüllmann-Rauch R, Stroobants S, Andersson C, Weigelt C, Eistrup C, Fogh J, D'Hooge R, Gieselmann V. Enzyme replacement improves ataxic gait and central nervous system histopathology in a mouse model of metachromatic leukodystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 600-6. PMID 19174759 DOI: 10.1038/mt.2008.305  0.68
2009 Leo S, Moechars D, Callaerts-Vegh Z, D'Hooge R, Meert T. Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity. European Journal of Pain (London, England). 13: 1008-17. PMID 19171494 DOI: 10.1016/j.ejpain.2008.12.001  0.68
2009 Van der Jeugd A, Goddyn H, Laeremans A, Arckens L, D'Hooge R, Verguts T. Hippocampal involvement in the acquisition of relational associations, but not in the expression of a transitive inference task in mice. Behavioral Neuroscience. 123: 109-14. PMID 19170435 DOI: 10.1037/a0013990  0.68
2009 Kerkhof I, Goesaert E, Dirikx T, Vansteenwegen D, Baeyens F, D'Hooge R, Hermans D. Assessing valence indirectly and online Cognition and Emotion. 23: 1615-1629. DOI: 10.1080/02699930802469239  0.68
2008 Denayer E, Ahmed T, Brems H, Van Woerden G, Borgesius NZ, Callaerts-Vegh Z, Yoshimura A, Hartmann D, Elgersma Y, D'Hooge R, Legius E, Balschun D. Spred1 is required for synaptic plasticity and hippocampus-dependent learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14443-9. PMID 19118178 DOI: 10.1523/JNEUROSCI.4698-08.2008  0.68
2008 Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, et al. Novel role for vascular endothelial growth factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10451-9. PMID 18923022 DOI: 10.1523/JNEUROSCI.1092-08.2008  0.68
2008 Errijgers V, Fransen E, D'Hooge R, De Deyn PP, Kooy RF. Effect of genetic background on acoustic startle response in fragile X knockout mice. Genetics Research. 90: 341-5. PMID 18840308 DOI: 10.1017/S0016672308009415  0.68
2008 Blanz J, Stroobants S, Lüllmann-Rauch R, Morelle W, Lüdemann M, D'Hooge R, Reuterwall H, Michalski JC, Fogh J, Andersson C, Saftig P. Reversal of peripheral and central neural storage and ataxia after recombinant enzyme replacement therapy in alpha-mannosidosis mice. Human Molecular Genetics. 17: 3437-45. PMID 18713755 DOI: 10.1093/hmg/ddn237  0.68
2008 Dejaegere T, Serneels L, Schäfer MK, Van Biervliet J, Horré K, Depboylu C, Alvarez-Fischer D, Herreman A, Willem M, Haass C, Höglinger GU, D'Hooge R, De Strooper B. Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment. Proceedings of the National Academy of Sciences of the United States of America. 105: 9775-80. PMID 18626010 DOI: 10.1073/pnas.0800507105  0.68
2008 Leo S, Straetemans R, D'Hooge R, Meert T. Differences in nociceptive behavioral performance between C57BL/6J, 129S6/SvEv, B6 129 F1 and NMRI mice. Behavioural Brain Research. 190: 233-42. PMID 18420287 DOI: 10.1016/j.bbr.2008.03.001  0.68
2008 Hulshagen L, Krysko O, Bottelbergs A, Huyghe S, Klein R, Van Veldhoven PP, De Deyn PP, D'Hooge R, Hartmann D, Baes M. Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4015-27. PMID 18400901 DOI: 10.1523/JNEUROSCI.4968-07.2008  0.68
2008 Stroobants S, Leroy T, Eckhardt M, Aerts JM, Berckmans D, D'Hooge R. Early signs of neurolipidosis-related behavioural alterations in a murine model of metachromatic leukodystrophy. Behavioural Brain Research. 189: 306-16. PMID 18336930 DOI: 10.1016/j.bbr.2008.01.008  0.68
2008 Berkovic SF, Dibbens LM, Oshlack A, Silver JD, Katerelos M, Vears DF, Lüllmann-Rauch R, Blanz J, Zhang KW, Stankovich J, Kalnins RM, Dowling JP, Andermann E, Andermann F, Faldini E, et al. Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. American Journal of Human Genetics. 82: 673-84. PMID 18308289 DOI: 10.1016/j.ajhg.2007.12.019  0.68
2008 Goddyn H, Callaerts-Vegh Z, Stroobants S, Dirikx T, Vansteenwegen D, Hermans D, van der Putten H, D'Hooge R. Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice. Neurobiology of Learning and Memory. 90: 103-11. PMID 18289889 DOI: 10.1016/j.nlm.2008.01.001  0.68
2008 Martins IC, Kuperstein I, Wilkinson H, Maes E, Vanbrabant M, Jonckheere W, Van Gelder P, Hartmann D, D'Hooge R, De Strooper B, Schymkowitz J, Rousseau F. Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. The Embo Journal. 27: 224-33. PMID 18059472 DOI: 10.1038/sj.emboj.7601953  0.68
2008 Poesen K, Lambrechts D, Van Damme P, Dhondt J, Bender F, Frank N, Bogaert E, Claes B, Heylen L, Verheyen A, Raes K, Tjwa M, Eriksson U, Shibuya M, Nuydens R, et al. Novel role for Vascular Endotheial Growth Factor (VEGF) receptor-1 and its ligand VEGF-B in motor neuron degeneration (Journal of Neuroscience (October 15, 2008) (10451-10459)) Journal of Neuroscience. 28: 1P.  0.68
2007 Dirikx T, Beckers T, Muyls C, Eelen P, Vansteenwegen D, Hermans D, D'Hooge R. Differential acquisition, extinction, and reinstatement of conditioned suppression in mice. Quarterly Journal of Experimental Psychology (2006). 60: 1313-20. PMID 17853239 DOI: 10.1080/17470210701515785  0.68
2007 Matzner U, Matthes F, Herbst E, Lüllmann-Rauch R, Callaerts-Vegh Z, D'Hooge R, Weigelt C, Eistrup C, Fogh J, Gieselmann V. Induction of tolerance to human arylsulfatase A in a mouse model of metachromatic leukodystrophy. Molecular Medicine (Cambridge, Mass.). 13: 471-9. PMID 17660863 DOI: 10.2119/2007-00063.Matzner  0.68
2007 Bollen B, Bouslama M, Matrot B, D'Hooge R, Van den Bergh O, Gallego J. Learned defense response to hypoxia in newborn mice. Neuroscience Letters. 420: 268-72. PMID 17532570 DOI: 10.1016/j.neulet.2007.05.012  0.68
2007 Errijgers V, Van Dam D, Gantois I, Van Ginneken CJ, Grossman AW, D'Hooge R, De Deyn PP, Kooy RF. FVB.129P2-Pde6b(+) Tyr(c-ch)/Ant, a sighted variant of the FVB/N mouse strain suitable for behavioral analysis. Genes, Brain, and Behavior. 6: 552-7. PMID 17083330 DOI: 10.1111/j.1601-183X.2006.00282.x  0.68
2006 Moechars D, Weston MC, Leo S, Callaerts-Vegh Z, Goris I, Daneels G, Buist A, Cik M, van der Spek P, Kass S, Meert T, D'Hooge R, Rosenmund C, Hampson RM. Vesicular glutamate transporter VGLUT2 expression levels control quantal size and neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12055-66. PMID 17108179 DOI: 10.1523/JNEUROSCI.2556-06.2006  0.68
2006 Vloeberghs E, Van Dam D, D'Hooge R, Staufenbiel M, De Deyn PP. APP23 mice display working memory impairment in the plus-shaped water maze. Neuroscience Letters. 407: 6-10. PMID 16959424 DOI: 10.1016/j.neulet.2006.07.060  0.68
2006 Franken S, Wittke D, Mansson JE, D'Hooge R, De Deyn PP, Lüllmann-Rauch R, Matzner U, Gieselmann V. Modest phenotypic improvements in ASA-deficient mice with only one UDP-galactose:ceramide-galactosyltransferase gene. Lipids in Health and Disease. 5: 21. PMID 16893448 DOI: 10.1186/1476-511X-5-21  0.68
2006 Goddyn H, Leo S, Meert T, D'Hooge R. Differences in behavioural test battery performance between mice with hippocampal and cerebellar lesions. Behavioural Brain Research. 173: 138-47. PMID 16860407 DOI: 10.1016/j.bbr.2006.06.016  0.68
2006 Cromphout K, Vleugels W, Heykants L, Schollen E, Keldermans L, Sciot R, D'Hooge R, De Deyn PP, von Figura K, Hartmann D, Körner C, Matthijs G. The normal phenotype of Pmm1-deficient mice suggests that Pmm1 is not essential for normal mouse development. Molecular and Cellular Biology. 26: 5621-35. PMID 16847318 DOI: 10.1128/MCB.02357-05  0.68
2006 Cipolat S, Rudka T, Hartmann D, Costa V, Serneels L, Craessaerts K, Metzger K, Frezza C, Annaert W, D'Adamio L, Derks C, Dejaegere T, Pellegrini L, D'Hooge R, Scorrano L, et al. Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. Cell. 126: 163-75. PMID 16839884 DOI: 10.1016/j.cell.2006.06.021  0.68
2006 Callaerts-Vegh Z, Beckers T, Ball SM, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R. Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6573-82. PMID 16775145 DOI: 10.1523/JNEUROSCI.1497-06.2006  0.68
2006 Rooms L, Reyniers E, Scheers S, van Luijk R, Wauters J, Van Aerschot L, Callaerts-Vegh Z, D'Hooge R, Mengus G, Davidson I, Courtens W, Kooy RF. TBP as a candidate gene for mental retardation in patients with subtelomeric 6q deletions. European Journal of Human Genetics : Ejhg. 14: 1090-6. PMID 16773126 DOI: 10.1038/sj.ejhg.5201674  0.68
2006 Caeyenberghs K, Balschun D, Roces DP, Schwake M, Saftig P, D'Hooge R. Multivariate neurocognitive and emotional profile of a mannosidosis murine model for therapy assessment. Neurobiology of Disease. 23: 422-32. PMID 16766199 DOI: 10.1016/j.nbd.2006.03.009  0.68
2006 Gantois I, Vandesompele J, Speleman F, Reyniers E, D'Hooge R, Severijnen LA, Willemsen R, Tassone F, Kooy RF. Expression profiling suggests underexpression of the GABA(A) receptor subunit delta in the fragile X knockout mouse model. Neurobiology of Disease. 21: 346-57. PMID 16199166 DOI: 10.1016/j.nbd.2005.07.017  0.68
2006 Dirikx T, Gillard E, Muyls C, Beckers T, Hermans D, Vansteenwegen D, D'Hooge R. Reinstatement of conditioned suppression in mice Psychologica Belgica. 46: 185-195.  0.68
2005 D'Hooge R, Lüllmann-Rauch R, Beckers T, Balschun D, Schwake M, Reiss K, von Figura K, Saftig P. Neurocognitive and psychotiform behavioral alterations and enhanced hippocampal long-term potentiation in transgenic mice displaying neuropathological features of human alpha-mannosidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6539-49. PMID 16014715 DOI: 10.1523/JNEUROSCI.0283-05.2005  0.68
2005 Dominguez D, Tournoy J, Hartmann D, Huth T, Cryns K, Deforce S, Serneels L, Camacho IE, Marjaux E, Craessaerts K, Roebroek AJ, Schwake M, D'Hooge R, Bach P, Kalinke U, et al. Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice. The Journal of Biological Chemistry. 280: 30797-806. PMID 15987683 DOI: 10.1074/jbc.M505249200  0.68
2005 Torremans A, Marescau B, Possemiers I, Van Dam D, D'Hooge R, Isbrandt D, De Deyn PP. Biochemical and behavioural phenotyping of a mouse model for GAMT deficiency. Journal of the Neurological Sciences. 231: 49-55. PMID 15792821 DOI: 10.1016/j.jns.2004.12.014  0.68
2005 Torremans A, Marescau B, Van Dam D, Van Ginneken C, Van Meir F, Van Bogaert PP, D'Hooge R, de Vente J, De Deyn PP. GSA: behavioral, histological, electrophysiological and neurochemical effects. Physiology & Behavior. 84: 251-64. PMID 15708777 DOI: 10.1016/j.physbeh.2004.12.001  0.68
2004 Torremans A, D'Hooge R, Van de Vijver G, Marescau B, Vanholder R, Lameire N, De Deyn PP, Van Bogaert PP. Effect of NaCN on currents evoked by uremic retention solutes in dissociated mouse neurons. Brain Research. 1008: 107-12. PMID 15081387 DOI: 10.1016/j.brainres.2004.02.021  0.68
2003 Gieselmann V, Franken S, Klein D, Mansson JE, Sandhoff R, Lüllmann Rauch R, Hartmann D, Saravanan VP, De Deyn PP, D'Hooge R, Van Der Linden AM, Schaeren-Wiemers N. Metachromatic leukodystrophy: consequences of sulphatide accumulation. Acta Paediatrica (Oslo, Norway : 1992). Supplement. 92: 74-9; discussion 45. PMID 14989469  0.68
2003 Van Camp N, D'Hooge R, Verhoye M, Peeters RR, De Deyn PP, Van der Linden A. Simultaneous electroencephalographic recording and functional magnetic resonance imaging during pentylenetetrazol-induced seizures in rat. Neuroimage. 19: 627-36. PMID 12880793 DOI: 10.1016/S1053-8119(03)00138-1  0.68
2003 Frints SG, Marynen P, Hartmann D, Fryns JP, Steyaert J, Schachner M, Rolf B, Craessaerts K, Snellinx A, Hollanders K, D'Hooge R, De Deyn PP, Froyen G. CALL interrupted in a patient with non-specific mental retardation: gene dosage-dependent alteration of murine brain development and behavior. Human Molecular Genetics. 12: 1463-74. PMID 12812975 DOI: 10.1093/hmg/ddg165  0.68
2003 Gieselmann V, Matzner U, Klein D, Mansson JE, D'Hooge R, DeDeyn PD, Lüllmann Rauch R, Hartmann D, Harzer K. Gene therapy: prospects for glycolipid storage diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 921-5. PMID 12803926 DOI: 10.1098/rstb.2003.1277  0.68
2003 De Deyn PP, Vanholder R, D'Hooge R. Nitric oxide in uremia: effects of several potentially toxic guanidino compounds. Kidney International. Supplement. S25-8. PMID 12694302 DOI: 10.1046/j.1523-1755.63.s84.9.x  0.68
2003 D'Hooge R, Van de Vijver G, Van Bogaert PP, Marescau B, Vanholder R, De Deyn PP. Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins. Kidney International. 63: 1764-75. PMID 12675852 DOI: 10.1046/j.1523-1755.2003.00912.x  0.68
2003 Gamp AC, Tanaka Y, Lüllmann-Rauch R, Wittke D, D'Hooge R, De Deyn PP, Moser T, Maier H, Hartmann D, Reiss K, Illert AL, von Figura K, Saftig P. LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice. Human Molecular Genetics. 12: 631-46. PMID 12620969 DOI: 10.1093/hmg/12.6.631  0.68
2003 Van Dam D, D'Hooge R, Staufenbiel M, Van Ginneken C, Van Meir F, De Deyn PP. Age-dependent cognitive decline in the APP23 model precedes amyloid deposition. The European Journal of Neuroscience. 17: 388-96. PMID 12542676 DOI: 10.1046/j.1460-9568.2003.02444.x  0.68
2002 Matzner U, Hartmann D, Lüllmann-Rauch R, Coenen R, Rothert F, MÃ¥nsson JE, Fredman P, D'Hooge R, De Deyn PP, Gieselmann V. Bone marrow stem cell-based gene transfer in a mouse model for metachromatic leukodystrophy: effects on visceral and nervous system disease manifestations. Gene Therapy. 9: 53-63. PMID 11850723 DOI: 10.1038/sj.gt.3301593  0.68
2001 Al Banchaabouchi M, Marescau B, D'Hooge R, De Deyn PP. The effect of high protein diet on urea and guanidino compound levels in renal insufficient mice. Amino Acids. 21: 401-15. PMID 11858699 DOI: 10.1007/s007260170005  0.68
2001 Al Banchaabouchi M, Marescau B, Van Marck E, D'hooge R, De Deyn PP. Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice. Metabolism: Clinical and Experimental. 50: 1418-25. PMID 11735086 DOI: 10.1053/meta.2001.26763  0.68
2001 de Jonge WJ, Marescau B, D'Hooge R, De Deyn PP, Hallemeesch MM, Deutz NE, Ruijter JM, Lamers WH. Overexpression of arginase alters circulating and tissue amino acids and guanidino compounds and affects neuromotor behavior in mice. The Journal of Nutrition. 131: 2732-40. PMID 11584097  0.68
2001 Al Banchaabouchi M, Marescau B, D'Hooge R, Van Marck E, De Deyn PP. Biochemical, histological and behavioral consequences of nephrectomy in young and aged mice. Nephron. 89: 90-100. PMID 11528238 DOI: 10.1159/000046049  0.68
2001 D'Hooge R, De Deyn PP. Applications of the Morris water maze in the study of learning and memory. Brain Research. Brain Research Reviews. 36: 60-90. PMID 11516773 DOI: 10.1016/S0165-0173(01)00067-4  0.68
2001 D'Hooge R, Van Dam D, Franck F, Gieselmann V, De Deyn PP. Hyperactivity, neuromotor defects, and impaired learning and memory in a mouse model for metachromatic leukodystrophy. Brain Research. 907: 35-43. PMID 11430883 DOI: 10.1016/S0006-8993(01)02374-5  0.68
2001 Matzner U, Schestag F, Hartmann D, Lüllmann-Rauch R, D'Hooge R, De Deyn PP, Gieselmann V. Bone marrow stem cell gene therapy of arylsulfatase A-deficient mice, using an arylsulfatase A mutant that is hypersecreted from retrovirally transduced donor-type cells. Human Gene Therapy. 12: 1021-33. PMID 11399225 DOI: 10.1089/104303401750214258  0.68
2001 De Deyn PP, D'Hooge R, Van Bogaert PP, Marescau B. Endogenous guanidino compounds as uremic neurotoxins. Kidney International. Supplement. 78: S77-83. PMID 11168988 DOI: 10.1046/j.1523-1755.2001.59780077.x  0.68
2001 Mariën P, Engelborghs S, D'Hooge R, De Deyn PP. Familial sinistrality in crossed aphasia: A new case and review of the available literature Aphasiology. 15: 1143-1168. DOI: 10.1080/02687040143000582  0.68
2000 Engelborghs S, D'Hooge R, De Deyn PP. Pathophysiology of epilepsy. Acta Neurologica Belgica. 100: 201-13. PMID 11233674  0.68
2000 Van Dam D, D'Hooge R, Hauben E, Reyniers E, Gantois I, Bakker CE, Oostra BA, Kooy RF, De Deyn PP. Spatial learning, contextual fear conditioning and conditioned emotional response in Fmr1 knockout mice. Behavioural Brain Research. 117: 127-36. PMID 11099766 DOI: 10.1016/S0166-4328(00)00296-5  0.68
2000 D'Hooge R, Marescau B, Qureshi IA, De Deyn PP. Impaired cognitive performance in ornithine transcarbamylase-deficient mice on arginine-free diet. Brain Research. 876: 1-9. PMID 10973586 DOI: 10.1016/S0006-8993(00)02589-0  0.68
2000 Al Banchaabouchi M, Marescau B, D'Hooge R, Engelborghs S, De Deyn PP. Consequences of renal mass reduction on amino acid and biogenic amine levels in nephrectomized mice. Amino Acids. 18: 265-77. PMID 10901623  0.68
2000 Al Banchaabouchi M, Marescau B, Possemiers I, D'Hooge R, Levillain O, De Deyn PP. NG, NG-dimethylarginine and NG, NG-dimethylarginine in renal insufficiency. PflüGers Archiv : European Journal of Physiology. 439: 524-31. PMID 10764210 DOI: 10.1007/s004240050973  0.68
2000 Bakker CE, Kooy RF, D'Hooge R, Tamanini F, Willemsen R, Nieuwenhuizen I, De Vries BBA, Reyniers E, Hoogeveen AT, Willems PJ, De Deyn PP, Oostra BA. Introduction of a FMR1 transgene in the fragile X knockout mouse Neuroscience Research Communications. 26: 265-277. DOI: 10.1002/1520-6769(200005/06)26:3<265::AID-NRC13>3.0.CO;2-T  0.68
2000 De Deyn PP, De Baets M, D'Hooge R. Neurosciences Research Communications: Foreword Neuroscience Research Communications. 26: 139. DOI: 10.1002/1520-6769(200005/06)26:3<139::AID-NRC1>3.0.CO;2-B  0.68
2000 De Deyn PP, D'Hooge R, Van Zutphen LFM. Animal models of human disorders-general aspects Neuroscience Research Communications. 26: 141-148.  0.68
1999 Al Banchaabouchi M, D'Hooge R, Marescau B, De Deyn PP. Behavioural deficits during the acute phase of mild renal failure in mice. Metabolic Brain Disease. 14: 173-87. PMID 10646693  0.68
1999 D'hooge R, Franck F, Mucke L, De Deyn PP. Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120. The European Journal of Neuroscience. 11: 4398-402. PMID 10594667  0.68
1999 D'Hooge R, Coenen R, Gieselmann V, Lüllmann-Rauch R, De Deyn PP. Decline in brainstem auditory-evoked potentials coincides with loss of spiral ganglion cells in arylsulfatase A-deficient mice. Brain Research. 847: 352-6. PMID 10575108 DOI: 10.1016/S0006-8993(99)02085-5  0.68
1999 D'Hooge R, Hartmann D, Manil J, Colin F, Gieselmann V, De Deyn PP. Neuromotor alterations and cerebellar deficits in aged arylsulfatase A-deficient transgenic mice. Neuroscience Letters. 273: 93-6. PMID 10505624 DOI: 10.1016/S0304-3940(99)00647-3  0.68
1999 Engelborghs S, De Brabander M, De Crée J, D'Hooge R, Geerts H, Verhaegen H, De Deyn PP. Unchanged levels of interleukins, neopterin, interferon-gamma and tumor necrosis factor-alpha in cerebrospinal fluid of patients with dementia of the Alzheimer type. Neurochemistry International. 34: 523-30. PMID 10402228 DOI: 10.1016/S0197-0186(99)00031-5  0.68
1999 D'Hooge R, De Deyn PP, Van de Vijver G, Antoons G, Raes A, Van Bogaert PP. Uraemic guanidino compounds inhibit gamma-aminobutyric acid-evoked whole cell currents in mouse spinal cord neurones. Neuroscience Letters. 265: 83-6. PMID 10327174 DOI: 10.1016/S0304-3940(99)00190-1  0.68
1999 D'Hooge R, Raes A, Van de Vijver G, Van Bogaert PP, De Deyn PP. Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones. Fundamental & Clinical Pharmacology. 13: 67-74. PMID 10027090  0.68
1998 Fransen E, D'Hooge R, Van Camp G, Verhoye M, Sijbers J, Reyniers E, Soriano P, Kamiguchi H, Willemsen R, Koekkoek SK, De Zeeuw CI, De Deyn PP, Van der Linden A, Lemmon V, Kooy RF, et al. L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns. Human Molecular Genetics. 7: 999-1009. PMID 9580664 DOI: 10.1093/hmg/7.6.999  0.68
1998 Al Banchaabouchi M, Marescau B, D'Hooge R, Van Marck E, Van Daele A, Levillain O, De Deyn PP. Biochemical and histopathological changes in nephrectomized mice. Metabolism: Clinical and Experimental. 47: 355-61. PMID 9500577 DOI: 10.1016/S0026-0495(98)90271-2  0.68
1996 D'Hooge R, Nagels G, Westland CE, Mucke L, De Deyn PP. Spatial learning deficit in mice expressing human 751-amino acid beta-amyloid precursor protein. Neuroreport. 7: 2807-11. PMID 8981472  0.68
1995 De Deyn PP, Marescau B, D'Hooge R, Possemiers I, Nagler J, Mahler C. Guanidino compound levels in brain regions of non-dialyzed uremic patients. Neurochemistry International. 27: 227-37. PMID 8520461  0.68
1994 D'Hooge R, Pei YQ, Marescau B, De Deyn PP. Ontogenetic differences in convulsive action and cerebral uptake of uremic guanidino compounds in juvenile mice. Neurochemistry International. 24: 215-20. PMID 8025530 DOI: 10.1016/0197-0186(94)90078-7  0.68
1992 D'Hooge R, Pei YQ, Marescau B, De Deyn PP. Behavioral toxicity of guanidinosuccinic acid in adult and young mice. Toxicology Letters. 64: 773-7. PMID 1471235 DOI: 10.1016/0378-4274(92)90261-H  0.68
1992 D'Hooge R, Pei YQ, Marescau B, De Deyn PP. Convulsive action and toxicity of uremic guanidino compounds: behavioral assessment and relation to brain concentration in adult mice. Journal of the Neurological Sciences. 112: 96-105. PMID 1469446 DOI: 10.1016/0022-510X(92)90138-B  0.68
1992 De Deyn PP, D'Hooge R, Marescau B, Pei YQ. Chemical models of epilepsy with some reference to their applicability in the development of anticonvulsants. Epilepsy Research. 12: 87-110. PMID 1396544 DOI: 10.1016/0920-1211(92)90030-W  0.68
1992 De Deyn PP, Saxena VK, Abts H, Borggreve F, D'Hooge R, Marescau B, Crols R. Clinical and pathophysiological aspects of neurological complications in renal failure. Acta Neurologica Belgica. 92: 191-206. PMID 1332359  0.68
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