Deborah J. Lenschow - Publications

Affiliations: 
Biology & Biomedical Sciences (Immunology) Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Virology Biology, Molecular Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hiller BE, Yin Y, Perng YC, de Araujo Castro Í, Fox LE, Locke MC, Monte KJ, López CB, Ornitz DM, Lenschow DJ. Fibroblast growth factor-9 expression in airway epithelial cells amplifies the type I interferon response and alters influenza A virus pathogenesis. Plos Pathogens. 18: e1010228. PMID 35675358 DOI: 10.1371/journal.ppat.1010228  0.43
2021 Locke MC, Fox LE, Dunlap BF, Young AR, Monte K, Lenschow DJ. IFNα, but not IFNβ, acts early to control chronic chikungunya virus pathogenesis. Journal of Virology. JVI0114321. PMID 34668781 DOI: 10.1128/JVI.01143-21  0.379
2020 Fox LE, Locke MC, Lenschow DJ. Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease. Frontiers in Immunology. 11: 606874. PMID 33408718 DOI: 10.3389/fimmu.2020.606874  0.308
2020 Bhushan J, Radke JB, Perng YC, Mcallaster M, Lenschow DJ, Virgin HW, Sibley LD. ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells. Mbio. 11. PMID 33024031 DOI: 10.1128/mBio.00852-20  0.361
2020 Swaim CD, Canadeo LA, Monte KJ, Khanna S, Lenschow DJ, Huibregtse JM. Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins. Cell Reports. 31: 107772. PMID 32553163 DOI: 10.1016/J.Celrep.2020.107772  0.437
2019 Cook LE, Locke MC, Young AR, Monte K, Hedberg ML, Shimak RM, Sheehan KCF, Veis DJ, Diamond MS, Lenschow DJ. Distinct roles of interferon alpha and beta in controlling chikungunya virus replication and modulating neutrophil-mediated inflammation. Journal of Virology. PMID 31619554 DOI: 10.1128/Jvi.00841-19  0.45
2019 Young AR, Locke MC, Cook LE, Hiller BE, Zhang R, Hedberg ML, Monte KJ, Veis DJ, Diamond MS, Lenschow DJ. Dermal and muscle fibroblasts and skeletal myofibers survive chikungunya virus infection and harbor persistent RNA. Plos Pathogens. 15: e1007993. PMID 31465513 DOI: 10.1371/Journal.Ppat.1007993  0.418
2018 Kulkarni HS, Elvington ML, Perng YC, Liszewski MK, Byers DE, Farkouh C, Yusen RD, Lenschow DJ, Brody SL, Atkinson JP. Intracellular C3 Protects Human Airway Epithelial Cells from Stress-Associated Cell Death. American Journal of Respiratory Cell and Molecular Biology. PMID 30156437 DOI: 10.1165/Rcmb.2017-0405Oc  0.344
2018 Perng YC, Lenschow DJ. ISG15 in antiviral immunity and beyond. Nature Reviews. Microbiology. PMID 29769653 DOI: 10.1038/S41579-018-0020-5  0.496
2018 Miner JJ, Lenschow DJ. Lessons learned from Chikungunya in the Americas. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29361204 DOI: 10.1002/Art.40421  0.386
2018 Kulkarni H, Elvington M, Perng Y, Liszewski MK, Frakouh C, Byers D, Lenschow D, Brody S, Atkinson J. Intracellular C3 protects human airway epithelial cells from oxidative-stress induced cell death Molecular Immunology. 102: 177-178. DOI: 10.1016/J.Molimm.2018.06.130  0.382
2017 Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS. The microbial metabolite desaminotyrosine protects from influenza through type I interferon. Science (New York, N.Y.). 357: 498-502. PMID 28774928 DOI: 10.1126/Science.Aam5336  0.48
2017 Burt FJ, Chen W, Miner JJ, Lenschow DJ, Merits A, Schnettler E, Kohl A, Rudd PA, Taylor A, Herrero LJ, Zaid A, Ng LF, Mahalingam S. Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen. The Lancet. Infectious Diseases. PMID 28159534 DOI: 10.1016/S1473-3099(16)30385-1  0.48
2017 Miner JJ, Cook LE, Hong JP, Smith AM, Richner JM, Shimak RM, Young AR, Monte K, Poddar S, Crowe JE, Lenschow DJ, Diamond MS. Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis. Science Translational Medicine. 9. PMID 28148840 DOI: 10.1126/Scitranslmed.Aah3438  0.443
2017 Kimmey JM, Campbell JA, Weiss LA, Monte KJ, Lenschow DJ, Stallings CL. The impact of ISGylation during Mycobacterium tuberculosis infection in mice. Microbes and Infection. PMID 28087453 DOI: 10.1016/J.Micinf.2016.12.006  0.448
2016 Steed A, Sun L, David M, Esaulova E, Artyomov M, Lenschow D, Stappenbeck T. 660: THE ROLE OF TYPE I INTERFERON DURING INFLUENZA A INFECTION. Critical Care Medicine. 44: 241. PMID 27850299 DOI: 10.1097/01.Ccm.0000509337.19815.97  0.449
2016 Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M, Duehr J, Sanal O, Tezcan I, Mansouri N, Tabarsi P, ... ... Lenschow DJ, et al. ISG15 deficiency and increased viral resistance in humans but not mice. Nature Communications. 7: 11496. PMID 27193971 DOI: 10.1038/Ncomms11496  0.436
2015 Nogales A, Rodríguez-Sánchez I, Monte K, Lenschow DJ, Perez DR, Martínez-Sobrido L. Replication-competent fluorescent-expressing influenza B virus. Virus Research. PMID 26590325 DOI: 10.1016/J.Virusres.2015.11.014  0.423
2015 Ketscher L, Hannß R, Morales DJ, Basters A, Guerra S, Goldmann T, Hausmann A, Prinz M, Naumann R, Pekosz A, Utermöhlen O, Lenschow DJ, Knobeloch KP. Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance. Proceedings of the National Academy of Sciences of the United States of America. 112: 1577-82. PMID 25605921 DOI: 10.1073/Pnas.1412881112  0.358
2015 Miner JJ, Aw Yeang HX, Fox JM, Taffner S, Malkova ON, Oh ST, Kim AH, Diamond MS, Lenschow DJ, Yokoyama WM. Chikungunya viral arthritis in the United States: a mimic of seronegative rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1214-20. PMID 25605621 DOI: 10.1002/Art.39027  0.341
2015 Sun L, Miyoshi H, Origanti S, Nice TJ, Barger AC, Manieri NA, Fogel LA, French AR, Piwnica-Worms D, Piwnica-Worms H, Virgin HW, Lenschow DJ, Stappenbeck TS. Type I interferons link viral infection to enhanced epithelial turnover and repair. Cell Host & Microbe. 17: 85-97. PMID 25482432 DOI: 10.1016/J.Chom.2014.11.004  0.483
2015 Morales DJ, Monte K, Sun L, Struckhoff JJ, Agapov E, Holtzman MJ, Stappenbeck TS, Lenschow DJ. Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice. Journal of Virology. 89: 337-49. PMID 25320315 DOI: 10.1128/Jvi.02110-14  0.532
2014 Perng YC, Campbell JA, Lenschow DJ, Yu D. Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription. Plos Pathogens. 10: e1004350. PMID 25166009 DOI: 10.1371/Journal.Ppat.1004350  0.419
2014 Deng X, Agnihothram S, Mielech AM, Nichols DB, Wilson MW, StJohn SE, Larsen SD, Mesecar AD, Lenschow DJ, Baric RS, Baker SC. A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses. Journal of Virology. 88: 11825-33. PMID 25100850 DOI: 10.1128/Jvi.01749-14  0.479
2014 Rodriguez MR, Monte K, Thackray LB, Lenschow DJ. ISG15 functions as an interferon-mediated antiviral effector early in the murine norovirus life cycle. Journal of Virology. 88: 9277-86. PMID 24899198 DOI: 10.1128/Jvi.01422-14  0.476
2014 Rohatgi A, Corbo JC, Monte K, Higgs S, Vanlandingham DL, Kardon G, Lenschow DJ. Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virus. Journal of Virology. 88: 2414-25. PMID 24335291 DOI: 10.1128/Jvi.02716-13  0.425
2014 Lubman OY, Cella M, Wang X, Monte K, Lenschow DJ, Huang YH, Fremont DH. Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor. Journal of Virology. 88: 538-46. PMID 24173234 DOI: 10.1128/Jvi.02729-13  0.375
2013 Morales DJ, Lenschow DJ. The antiviral activities of ISG15. Journal of Molecular Biology. 425: 4995-5008. PMID 24095857 DOI: 10.1016/J.Jmb.2013.09.041  0.45
2013 Campbell JA, Lenschow DJ. Emerging roles for immunomodulatory functions of free ISG15. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 728-38. PMID 24010825 DOI: 10.1089/Jir.2013.0064  0.48
2013 Shoji-Kawata S, Sumpter R, Leveno M, Campbell GR, Zou Z, Kinch L, Wilkins AD, Sun Q, Pallauf K, MacDuff D, Huerta C, Virgin HW, Helms JB, Eerland R, Tooze SA, ... ... Lenschow DJ, et al. Identification of a candidate therapeutic autophagy-inducing peptide. Nature. 494: 201-6. PMID 23364696 DOI: 10.1038/Nature11866  0.463
2012 Joubert PE, Werneke S, de la Calle C, Guivel-Benhassine F, Giodini A, Peduto L, Levine B, Schwartz O, Lenschow D, Albert ML. Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy. Autophagy. 8: 1261-3. PMID 22836517 DOI: 10.4161/Auto.20751  0.689
2012 Joubert PE, Werneke SW, de la Calle C, Guivel-Benhassine F, Giodini A, Peduto L, Levine B, Schwartz O, Lenschow DJ, Albert ML. Chikungunya virus-induced autophagy delays caspase-dependent cell death. The Journal of Experimental Medicine. 209: 1029-47. PMID 22508836 DOI: 10.1084/Jem.20110996  0.7
2012 Swiecki M, Wang Y, Gilfillan S, Lenschow DJ, Colonna M. Cutting edge: paradoxical roles of BST2/tetherin in promoting type I IFN response and viral infection. Journal of Immunology (Baltimore, Md. : 1950). 188: 2488-92. PMID 22327075 DOI: 10.4049/Jimmunol.1103145  0.53
2011 Werneke SW, Schilte C, Rohatgi A, Monte KJ, Michault A, Arenzana-Seisdedos F, Vanlandingham DL, Higgs S, Fontanet A, Albert ML, Lenschow DJ. ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation. Plos Pathogens. 7: e1002322. PMID 22028657 DOI: 10.1371/Journal.Ppat.1002322  0.685
2011 Nakka VP, Lang BT, Lenschow DJ, Zhang DE, Dempsey RJ, Vemuganti R. Increased cerebral protein ISGylation after focal ischemia is neuroprotective. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 2375-84. PMID 21847135 DOI: 10.1038/Jcbfm.2011.103  0.309
2010 Lenschow DJ. Antiviral Properties of ISG15. Viruses. 2: 2154-68. PMID 21994614 DOI: 10.3390/V2102154  0.531
2010 Versteeg GA, Hale BG, van Boheemen S, Wolff T, Lenschow DJ, García-Sastre A. Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein. Journal of Virology. 84: 5423-30. PMID 20219937 DOI: 10.1128/Jvi.02395-09  0.384
2009 Giannakopoulos NV, Arutyunova E, Lai C, Lenschow DJ, Haas AL, Virgin HW. ISG15 Arg151 and the ISG15-conjugating enzyme UbE1L are important for innate immune control of Sindbis virus. Journal of Virology. 83: 1602-10. PMID 19073728 DOI: 10.1128/Jvi.01590-08  0.447
2009 Lai C, Struckhoff JJ, Schneider J, Martinez-Sobrido L, Wolff T, García-Sastre A, Zhang DE, Lenschow DJ. Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection. Journal of Virology. 83: 1147-51. PMID 19004958 DOI: 10.1128/Jvi.00105-08  0.506
2007 Frias-Staheli N, Giannakopoulos NV, Kikkert M, Taylor SL, Bridgen A, Paragas J, Richt JA, Rowland RR, Schmaljohn CS, Lenschow DJ, Snijder EJ, García-Sastre A, Virgin HW. Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses. Cell Host & Microbe. 2: 404-16. PMID 18078692 DOI: 10.1016/J.Chom.2007.09.014  0.412
2007 Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, García-Sastre A, Leib DA, Pekosz A, Knobeloch KP, Horak I, Virgin HW. IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proceedings of the National Academy of Sciences of the United States of America. 104: 1371-6. PMID 17227866 DOI: 10.1073/Pnas.0607038104  0.546
2005 Lenschow DJ, Giannakopoulos NV, Gunn LJ, Johnston C, O'Guin AK, Schmidt RE, Levine B, Virgin HW. Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo. Journal of Virology. 79: 13974-83. PMID 16254333 DOI: 10.1128/Jvi.79.22.13974-13983.2005  0.474
2005 Giannakopoulos NV, Luo JK, Papov V, Zou W, Lenschow DJ, Jacobs BS, Borden EC, Li J, Virgin HW, Zhang DE. Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochemical and Biophysical Research Communications. 336: 496-506. PMID 16139798 DOI: 10.1016/J.Bbrc.2005.08.132  0.347
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