| Year |
Citation |
Score |
| 2020 |
Kaur S, Sarma SJ, Marshall BL, Liu Y, Kinkade JA, Bellamy MM, Mao J, Helferich WG, Schenk AK, Bivens NJ, Lei Z, Sumner LW, Bowden JA, Koelmel JP, Joshi T, et al. Developmental exposure of California mice to endocrine disrupting chemicals and potential effects on the microbiome-gut-brain axis at adulthood. Scientific Reports. 10: 10902. PMID 32616744 DOI: 10.1038/S41598-020-67709-9 |
0.309 |
|
| 2019 |
Song H, Hughes JR, Turner RT, Iwaniec UT, Doerge DR, Helferich WG. (±)-Equol does not interact with genistein on estrogen-dependent breast tumor growth. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 110979. PMID 31786350 DOI: 10.1016/J.Fct.2019.110979 |
0.448 |
|
| 2019 |
Marshall BL, Liu Y, Farrington MJ, Mao J, Helferich W, Schenk AK, Bivens NJ, Sarma SJ, Lei Z, Sumner LW, Joshi T, Rosenfeld CS. Early genistein exposure of California mice and gut microbiota-brain axis effects. The Journal of Endocrinology. PMID 31189133 DOI: 10.1530/Joe-19-0214 |
0.319 |
|
| 2019 |
Cam A, Oyirifi AB, Liu Y, Haschek WM, Iwaniec UT, Turner RT, Engeseth NJ, Helferich WG. Thermally Abused Frying Oil Potentiates Metastasis to Lung in a Murine Model of Late-Stage Breast Cancer. Cancer Prevention Research (Philadelphia, Pa.). PMID 30885926 DOI: 10.1158/1940-6207.Capr-18-0220 |
0.365 |
|
| 2019 |
Chen C, Chen JJ, Ma L, Helferich WG, Nelson ER. Abstract 1893: Consumption of oil derived from frying bacon increases breast cancer metastasis Cancer Research. 79: 1893-1893. DOI: 10.1158/1538-7445.Am2019-1893 |
0.409 |
|
| 2018 |
Yu L, Wang L, Mao C, Duraki D, Kim JE, Huang R, Helferich WG, Nelson ER, Park BH, Shapiro DJ. Estrogen-Independent Myc Overexpression Confers Endocrine Therapy Resistance on Breast Cancer Cells Expressing ERαY537S and ERαD538G Mutations. Cancer Letters. PMID 30419347 DOI: 10.1016/J.Canlet.2018.10.041 |
0.418 |
|
| 2018 |
Kundu P, Patel S, Meling DD, Deal K, Gao L, Helferich WG, Flaws JA. The Effects of Dietary Levels of Genistein on Ovarian Follicle Number and Gene Expression. Reproductive Toxicology (Elmsford, N.Y.). PMID 30056207 DOI: 10.1016/J.Reprotox.2018.07.085 |
0.304 |
|
| 2018 |
Yin Q, Tang L, Cai K, Yang X, Yin L, Zhang Y, Dobrucki LW, Helferich WG, Fan TM, Cheng J. Albumin as a "Trojan Horse" for polymeric nanoconjugate transendothelial transport across tumor vasculatures for improved cancer targeting. Biomaterials Science. PMID 29570190 DOI: 10.1039/C8Bm00149A |
0.394 |
|
| 2018 |
Kundu P, Neese S, Bandara S, Monaikul S, Helferich WG, Doerge DR, Khan IA, Schantz S. The effects of the botantical estrogen, isoliquiritigenin on delayed spatial alternation. Neurotoxicology and Teratology. PMID 29408209 DOI: 10.1016/J.Ntt.2018.02.001 |
0.341 |
|
| 2018 |
Hughes JR, Joyce KM, Cam A, Helferich WG, Madak-Erdogan Z. Abstract B26: Thermally abused frying oil enhances metastatic progression in vivo and in vitro: A link to elevated fumarate levels Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B26 |
0.373 |
|
| 2017 |
Wang H, Wu X, Lezmi S, Li Q, Helferich WG, Xu Y, Chen H. Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model. Bmc Complementary and Alternative Medicine. 17: 516. PMID 29197355 DOI: 10.1186/S12906-017-2014-7 |
0.359 |
|
| 2017 |
Wang W, Gordon JL, Philbrick KA, Yang X, Branscum AJ, Löhr CV, Haschek WM, Turner RT, Iwaniec UT, Helferich WG. Low calcium diet increases 4T1 mammary tumor carcinoma cell burden and bone pathology in mice. Plos One. 12: e0180886. PMID 28750038 DOI: 10.1371/Journal.Pone.0180886 |
0.383 |
|
| 2017 |
Zhang X, Cook KL, Warri A, Cruz IM, Rosim M, Riskin J, Helferich W, Doerge D, Clarke R, Hilakivi-Clarke L. Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: 814-824. PMID 28148690 DOI: 10.1158/1078-0432.Ccr-16-1735 |
0.441 |
|
| 2016 |
Mahalingam S, Gao L, Eisner J, Helferich W, Flaws JA. Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis. Reproductive Toxicology (Elmsford, N.Y.). PMID 27773742 DOI: 10.1016/J.Reprotox.2016.10.004 |
0.353 |
|
| 2016 |
Rendeiro C, Sheriff A, Bhattacharya TK, Gogola JV, Baxter JH, Chen H, Helferich WG, Roy EJ, Rhodes JS. Long-lasting impairments in adult neurogenesis, spatial learning and memory from a standard chemotherapy regimen used to treat breast cancer. Behavioural Brain Research. PMID 27478140 DOI: 10.1016/J.Bbr.2016.07.043 |
0.342 |
|
| 2016 |
Yin Q, Tang L, Cai K, Tong R, Sternberg R, Yang X, Dobrucki LW, Borst LB, Kamstock D, Song Z, Helferich WG, Cheng J, Fan TM. Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27457945 DOI: 10.1073/Pnas.1603316113 |
0.308 |
|
| 2016 |
Wang W, Belosay A, Yang X, Hartman JA, Song H, Iwaniec UT, Turner RT, Churchwell MI, Doerge DR, Helferich WG. Effects of letrozole on breast cancer micro-metastatic tumor growth in bone and lung in mice inoculated with murine 4T1 cells. Clinical & Experimental Metastasis. PMID 27209469 DOI: 10.1007/S10585-016-9792-Z |
0.462 |
|
| 2016 |
Zheng X, Andruska N, Yu L, Mao C, Kim JE, Livezey M, Helferich WG, Shapiro DJ. Interplay between steroid hormone activation of the unfolded protein response and nuclear receptor action. Steroids. PMID 27016130 DOI: 10.1016/J.Steroids.2016.03.014 |
0.43 |
|
| 2016 |
Mahalingam S, Gao L, Gonnering M, Helferich W, Flaws JA. Equol inhibits growth, induces atresia, and inhibits steroidogenesis of mouse antral follicles in vitro. Toxicology and Applied Pharmacology. 295: 47-55. PMID 26876617 DOI: 10.1016/J.Taap.2016.02.009 |
0.336 |
|
| 2016 |
Patel S, Peretz J, Pan YX, Helferich WG, Flaws JA. Genistein exposure inhibits growth and alters steroidogenesis in adult mouse antral follicles. Toxicology and Applied Pharmacology. 293: 53-62. PMID 26792615 DOI: 10.1016/J.Taap.2015.12.026 |
0.335 |
|
| 2015 |
Aumsuwan P, Khan SI, Khan IA, Ali Z, Avula B, Walker LA, Shariat-Madar Z, Helferich WG, Katzenellenbogen BS, Dasmahapatra AK. The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro. Archives of Biochemistry and Biophysics. PMID 26682631 DOI: 10.1016/J.Abb.2015.12.001 |
0.417 |
|
| 2015 |
Boonmuen N, Gong P, Ali Z, Chittiboyina AG, Khan I, Doerge DR, Helferich WG, Carlson KE, Martin T, Piyachaturawat P, Katzenellenbogen JA, Katzenellenbogen BS. Licorice Root Components in Dietary Supplements are Selective Estrogen Receptor Modulators with a Spectrum of Estrogenic and Anti-Estrogenic Activities. Steroids. PMID 26631549 DOI: 10.1016/J.Steroids.2015.11.006 |
0.574 |
|
| 2015 |
Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin AR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, ... ... Helferich WG, et al. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars in Cancer Biology. 35: S276-304. PMID 26590477 DOI: 10.1016/J.Semcancer.2015.09.007 |
0.33 |
|
| 2015 |
Madak-Erdogan Z, Gong P, Zhao YC, Xu L, Wrobel KU, Hartman JA, Wang M, Cam A, Iwaniec UT, Turner RT, Twaddle NC, Doerge DR, Khan IA, Katzenellenbogen JA, Katzenellenbogen BS, ... Helferich WG, et al. Dietary licorice root supplementation reduces diet-induced weight gain, lipid deposition, and hepatic steatosis in ovariectomized mice without stimulating reproductive tissues and mammary gland. Molecular Nutrition & Food Research. PMID 26555669 DOI: 10.1002/Mnfr.201500445 |
0.32 |
|
| 2015 |
Strakovsky RS, Lezmi S, Shkoda I, Flaws JA, Helferich WG, Pan YX. In utero growth restriction and catch-up adipogenesis after developmental di (2-ethylhexyl) phthalate exposure cause glucose intolerance in adult male rats following a high-fat dietary challenge. The Journal of Nutritional Biochemistry. 26: 1208-20. PMID 26188368 DOI: 10.1016/J.Jnutbio.2015.05.012 |
0.317 |
|
| 2015 |
Cai K, Yen J, Yin Q, Liu Y, Song Z, Lezmi S, Zhang Y, Yang X, Helferich WG, Cheng J. Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics. Biomaterials Science. 3: 1061-1065. PMID 26146551 DOI: 10.1039/C4Bm00452C |
0.453 |
|
| 2015 |
Samadi AK, Bilsland A, Georgakilas AG, Amedei A, Amin A, Bishayee A, Azmi AS, Lokeshwar BL, Grue B, Panis C, Boosani CS, Poudyal D, Stafforini DM, Bhakta D, Niccolai E, ... ... Helferich WG, et al. A multi-targeted approach to suppress tumor-promoting inflammation. Seminars in Cancer Biology. PMID 25951989 DOI: 10.1016/J.Semcancer.2015.03.006 |
0.337 |
|
| 2015 |
Mohammad RM, Muqbil I, Lowe L, Yedjou C, Hsu HY, Lin LT, Siegelin MD, Fimognari C, Kumar NB, Dou QP, Yang H, Samadi AK, Russo GL, Spagnuolo C, Ray SK, ... ... Helferich WG, et al. Broad targeting of resistance to apoptosis in cancer. Seminars in Cancer Biology. PMID 25936818 DOI: 10.1016/J.Semcancer.2015.03.001 |
0.316 |
|
| 2015 |
Casey SC, Amedei A, Aquilano K, Azmi AS, Benencia F, Bhakta D, Bilsland AE, Boosani CS, Chen S, Ciriolo MR, Crawford S, Fujii H, Georgakilas AG, Guha G, Halicka D, ... Helferich WG, et al. Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars in Cancer Biology. PMID 25865775 DOI: 10.1016/J.Semcancer.2015.02.007 |
0.373 |
|
| 2015 |
Jiang WG, Sanders AJ, Katoh M, Ungefroren H, Gieseler F, Prince M, Thompson SK, Zollo M, Spano D, Dhawan P, Sliva D, Subbarayan PR, Sarkar M, Honoki K, Fujii H, ... ... Helferich WG, et al. Tissue invasion and metastasis: Molecular, biological and clinical perspectives. Seminars in Cancer Biology. PMID 25865774 DOI: 10.1016/J.Semcancer.2015.03.008 |
0.331 |
|
| 2015 |
Andruska ND, Zheng X, Yang X, Mao C, Cherian MM, Mahapatra L, Helferich WG, Shapiro DJ. Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regression. Proceedings of the National Academy of Sciences of the United States of America. 112: 4737-42. PMID 25825714 DOI: 10.1073/Pnas.1403685112 |
0.408 |
|
| 2015 |
Liu Y, Hilakivi-Clarke L, Zhang Y, Wang X, Pan YX, Xuan J, Fleck SC, Doerge DR, Helferich WG. Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice. Molecular Nutrition & Food Research. PMID 25820259 DOI: 10.1002/Mnfr.201500028 |
0.599 |
|
| 2015 |
Vinay DS, Ryan EP, Pawelec G, Talib WH, Stagg J, Elkord E, Lichtor T, Decker WK, Whelan RL, Kumara HM, Signori E, Honoki K, Georgakilas AG, Amin A, Helferich WG, et al. Immune evasion in cancer: Mechanistic basis and therapeutic strategies. Seminars in Cancer Biology. PMID 25818339 DOI: 10.1016/J.Semcancer.2015.03.004 |
0.345 |
|
| 2015 |
Yang X, Belosay A, Hartman JA, Song H, Zhang Y, Wang W, Doerge DR, Helferich WG. Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors. Clinical & Experimental Metastasis. 32: 323-33. PMID 25749878 DOI: 10.1007/S10585-015-9709-2 |
0.592 |
|
| 2015 |
Strakovsky RS, Wang H, Engeseth NJ, Flaws JA, Helferich WG, Pan YX, Lezmi S. Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis. Toxicology and Applied Pharmacology. 284: 101-12. PMID 25748669 DOI: 10.1016/J.Taap.2015.02.021 |
0.3 |
|
| 2015 |
Andruska N, Zheng X, Yang X, Helferich WG, Shapiro DJ. Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer. Oncogene. 34: 3760-9. PMID 25263449 DOI: 10.1038/Onc.2014.292 |
0.438 |
|
| 2015 |
Aumsuwan P, Khan SI, Khan IA, Avula B, Walker LA, Helferich WG, Katzenellenbogen BS, Dasmahapatra AK. Evaluation of wild yam (Dioscorea villosa) root extract as a potential epigenetic agent in breast cancer cells. In Vitro Cellular & Developmental Biology. Animal. 51: 59-71. PMID 25148825 DOI: 10.1007/S11626-014-9807-5 |
0.406 |
|
| 2015 |
Andrade JE, Ju YH, Baker C, Doerge DR, Helferich WG. Long-term exposure to dietary sources of genistein induces estrogen-independence in the human breast cancer (MCF-7) xenograft model. Molecular Nutrition & Food Research. 59: 413-23. PMID 24668689 DOI: 10.1002/Mnfr.201300780 |
0.428 |
|
| 2015 |
Zhang Y, Wang W, Yang X, Helferich WG. Abstract 899: High fat diet induced DNA methylation at transcription factor binding region and repressed gene expression of a metastasis suppressor E-cadherin in primary site of murine metastatic breast cancer (MBC), and promoted invasion of MBC cells to lung and liver Cancer Research. 75: 899-899. DOI: 10.1158/1538-7445.Am2015-899 |
0.615 |
|
| 2014 |
Gong P, Madak-Erdogan Z, Li J, Cheng J, Greenlief CM, Helferich W, Katzenellenbogen JA, Katzenellenbogen BS. Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens. Nuclear Receptor Signaling. 12: e001. PMID 25363786 DOI: 10.1621/Nrs.12001 |
0.372 |
|
| 2014 |
Tang L, Yang X, Yin Q, Cai K, Wang H, Chaudhury I, Yao C, Zhou Q, Kwon M, Hartman JA, Dobrucki IT, Dobrucki LW, Borst LB, Lezmi S, Helferich WG, et al. Investigating the optimal size of anticancer nanomedicine. Proceedings of the National Academy of Sciences of the United States of America. 111: 15344-9. PMID 25316794 DOI: 10.1073/Pnas.1411499111 |
0.319 |
|
| 2014 |
Neese SL, Pisani SL, Doerge DR, Helferich WG, Sepehr E, Chittiboyina AG, Rotte SC, Smillie TJ, Khan IA, Korol DL, Schantz SL. The effects of dietary treatment with S-equol on learning and memory processes in middle-aged ovariectomized rats. Neurotoxicology and Teratology. 41: 80-8. PMID 24368316 DOI: 10.1016/J.Ntt.2013.12.004 |
0.566 |
|
| 2014 |
Strakovsky RS, Lezmi S, Flaws JA, Schantz SL, Pan YX, Helferich WG. Genistein exposure during the early postnatal period favors the development of obesity in female, but not male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 138: 161-74. PMID 24361872 DOI: 10.1093/Toxsci/Kft331 |
0.328 |
|
| 2013 |
Xing H, Tang L, Yang X, Hwang K, Wang W, Yin Q, Wong NY, Dobrucki LW, Yasui N, Katzenellenbogen JA, Helferich WG, Cheng J, Lu Y. Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 1: 5288-5297. PMID 24159374 DOI: 10.1039/C3Tb20412J |
0.396 |
|
| 2013 |
Yang X, Belosay A, Du M, Fan TM, Turner RT, Iwaniec UT, Helferich WG. Estradiol increases ER-negative breast cancer metastasis in an experimental model. Clinical & Experimental Metastasis. 30: 711-21. PMID 24096710 DOI: 10.1007/S10585-012-9559-0 |
0.743 |
|
| 2013 |
Jiang Y, Gong P, Madak-Erdogan Z, Martin T, Jeyakumar M, Carlson K, Khan I, Smillie TJ, Chittiboyina AG, Rotte SC, Helferich WG, Katzenellenbogen JA, Katzenellenbogen BS. Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4406-18. PMID 23882126 DOI: 10.1096/Fj.13-234617 |
0.648 |
|
| 2013 |
Turner RT, Iwaniec UT, Andrade JE, Branscum AJ, Neese SL, Olson DA, Wagner L, Wang VC, Schantz SL, Helferich WG. Genistein administered as a once-daily oral supplement had no beneficial effect on the tibia in rat models for postmenopausal bone loss. Menopause (New York, N.Y.). 20: 677-86. PMID 23385720 DOI: 10.1097/Gme.0B013E31827D44Df |
0.301 |
|
| 2012 |
Du M, Yang X, Hartman JA, Cooke PS, Doerge DR, Ju YH, Helferich WG. Low-dose dietary genistein negates the therapeutic effect of tamoxifen in athymic nude mice. Carcinogenesis. 33: 895-901. PMID 22266527 DOI: 10.1093/Carcin/Bgs017 |
0.737 |
|
| 2012 |
Neese SL, Bandara SB, Doerge DR, Helferich WG, Korol DL, Schantz SL. Effects of multiple daily genistein treatments on delayed alternation and a differential reinforcement of low rates of responding task in middle-aged rats. Neurotoxicology and Teratology. 34: 187-95. PMID 21945133 DOI: 10.1016/J.Ntt.2011.09.002 |
0.315 |
|
| 2011 |
de Assis S, Warri A, Benitez C, Helferich W, Hilakivi-Clarke L. Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expression. Cancer Prevention Research (Philadelphia, Pa.). 4: 1436-48. PMID 21680703 DOI: 10.1158/1940-6207.Capr-10-0346 |
0.439 |
|
| 2010 |
Hilakivi-Clarke L, Andrade JE, Helferich W. Is soy consumption good or bad for the breast? The Journal of Nutrition. 140: 2326S-2334S. PMID 20980638 DOI: 10.3945/Jn.110.124230 |
0.44 |
|
| 2010 |
Hsu A, Bray TM, Helferich WG, Doerge DR, Ho E. Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells. Experimental Biology and Medicine (Maywood, N.J.). 235: 90-7. PMID 20404023 DOI: 10.1258/Ebm.2009.009128 |
0.337 |
|
| 2010 |
Cimafranca MA, Davila J, Ekman GC, Andrews RN, Neese SL, Peretz J, Woodling KA, Helferich WG, Sarkar J, Flaws JA, Schantz SL, Doerge DR, Cooke PS. Acute and chronic effects of oral genistein administration in neonatal mice. Biology of Reproduction. 83: 114-21. PMID 20357267 DOI: 10.1095/Biolreprod.109.080549 |
0.332 |
|
| 2010 |
Andrade JE, Twaddle NC, Helferich WG, Doerge DR. Absolute bioavailability of isoflavones from soy protein isolate-containing food in female BALB/c mice. Journal of Agricultural and Food Chemistry. 58: 4529-36. PMID 20225898 DOI: 10.1021/Jf9039843 |
0.329 |
|
| 2009 |
Zhang Y, Li Q, Wan HY, Helferich WG, Wong MS. Genistein and a soy extract differentially affect three-dimensional bone parameters and bone-specific gene expression in ovariectomized mice. The Journal of Nutrition. 139: 2230-6. PMID 19793844 DOI: 10.3945/Jn.109.108399 |
0.524 |
|
| 2009 |
Legette LL, Martin BR, Shahnazari M, Lee WH, Helferich WG, Qian J, Waters DJ, Arabshahi A, Barnes S, Welch J, Bostwick DG, Weaver CM. Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats. The Journal of Nutrition. 139: 1908-13. PMID 19710157 DOI: 10.3945/Jn.109.108225 |
0.337 |
|
| 2009 |
Iwaniec UT, Dube MG, Boghossian S, Song H, Helferich WG, Turner RT, Kalra SP. Body mass influences cortical bone mass independent of leptin signaling. Bone. 44: 404-12. PMID 19095090 DOI: 10.1016/J.Bone.2008.10.058 |
0.307 |
|
| 2008 |
Helferich WG, Andrade JE, Hoagland MS. Phytoestrogens and breast cancer: a complex story. Inflammopharmacology. 16: 219-26. PMID 18815740 DOI: 10.1007/S10787-008-8020-0 |
0.449 |
|
| 2008 |
Wang VC, Sable HJ, Ju YH, Allred CD, Helferich WG, Korol DL, Schantz SL. Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding. Behavioral Neuroscience. 122: 794-804. PMID 18729633 DOI: 10.1037/A0012513 |
0.304 |
|
| 2008 |
Jiang X, Patterson NM, Ling Y, Xie J, Helferich WG, Shapiro DJ. Low concentrations of the soy phytoestrogen genistein induce proteinase inhibitor 9 and block killing of breast cancer cells by immune cells. Endocrinology. 149: 5366-73. PMID 18669594 DOI: 10.1210/En.2008-0857 |
0.444 |
|
| 2008 |
Ju YH, Doerge DR, Woodling KA, Hartman JA, Kwak J, Helferich WG. Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo. Carcinogenesis. 29: 2162-8. PMID 18632754 DOI: 10.1093/Carcin/Bgn161 |
0.474 |
|
| 2008 |
Chang EC, Charn TH, Park SH, Helferich WG, Komm B, Katzenellenbogen JA, Katzenellenbogen BS. Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Molecular Endocrinology (Baltimore, Md.). 22: 1032-43. PMID 18258689 DOI: 10.1210/Me.2007-0356 |
0.376 |
|
| 2008 |
Ju YH, Doerge DR, Helferich WG. A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 310-20. PMID 17919800 DOI: 10.1016/J.Fct.2007.08.006 |
0.487 |
|
| 2006 |
Putt KS, Chen GW, Pearson JM, Sandhorst JS, Hoagland MS, Kwon JT, Hwang SK, Jin H, Churchwell MI, Cho MH, Doerge DR, Helferich WG, Hergenrother PJ. Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nature Chemical Biology. 2: 543-50. PMID 16936720 DOI: 10.1038/Nchembio814 |
0.336 |
|
| 2006 |
Ju YH, Allred KF, Allred CD, Helferich WG. Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations Carcinogenesis. 27: 1292-1299. PMID 16537557 DOI: 10.1093/Carcin/Bgi370 |
0.457 |
|
| 2006 |
Ju YH, Fultz J, Allred KF, Doerge DR, Helferich WG. Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice Carcinogenesis. 27: 856-863. PMID 16399773 DOI: 10.1093/Carcin/Bgi320 |
0.459 |
|
| 2005 |
Allred CD, Twaddle NC, Allred KF, Goeppinger TS, Churchwell MI, Ju YH, Helferich WG, Doerge DR. Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized Balb/c Mice Journal of Agricultural and Food Chemistry. 53: 8542-8550. PMID 16248551 DOI: 10.1021/Jf051246W |
0.411 |
|
| 2004 |
Selvaraj V, Zakroczymski MA, Naaz A, Mukai M, Ju YH, Doerge DR, Katzenellenbogen JA, Helferich WG, Cooke PS. Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice. Biology of Reproduction. 71: 966-72. PMID 15151933 DOI: 10.1095/Biolreprod.104.029512 |
0.387 |
|
| 2004 |
Allred CD, Allred KF, Ju YH, Goeppinger TS, Doerge DR, Helferich WG. Soy processing influences growth of estrogen-dependent breast cancer tumors Carcinogenesis. 25: 1649-1657. PMID 15131010 DOI: 10.1093/Carcin/Bgh178 |
0.47 |
|
| 2004 |
Ju YH, Clausen LM, Allred KF, Almada AL, Helferich WG. β-Sitosterol, β-Sitosterol Glucoside, and a Mixture of β-Sitosterol and β-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells in Vitro and in Ovariectomized Athymic Mice Journal of Nutrition. 134: 1145-1151. PMID 15113961 DOI: 10.1093/Jn/134.5.1145 |
0.454 |
|
| 2004 |
Allred CD, Allred KF, Ju YH, Clausen LM, Doerge DR, Schantz SL, Korol DL, Wallig MA, Helferich WG. Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis. 25: 211-8. PMID 14578162 DOI: 10.1093/Carcin/Bgg198 |
0.491 |
|
| 2003 |
Naaz A, Yellayi S, Zakroczymski MA, Bunick D, Doerge DR, Lubahn DB, Helferich WG, Cooke PS. The soy isoflavone genistein decreases adipose deposition in mice. Endocrinology. 144: 3315-20. PMID 12865308 DOI: 10.1210/En.2003-0076 |
0.373 |
|
| 2003 |
Yellayi S, Zakroczymski MA, Selvaraj V, Valli VE, Helferich WG, Cooke PS. The phytoestrogen genistein suppresses cell-mediated immunity in mice. The Journal of Endocrinology. 176: 267-74. PMID 12553875 DOI: 10.1677/Joe.0.1760267 |
0.384 |
|
| 2002 |
Yellayi S, Naaz A, Szewczykowski MA, Sato T, Woods JA, Chang J, Segre M, Allred CD, Helferich WG, Cooke PS. The phytoestrogen genistein induces thymic and immune changes: a human health concern? Proceedings of the National Academy of Sciences of the United States of America. 99: 7616-21. PMID 12032332 DOI: 10.1073/Pnas.102650199 |
0.303 |
|
| 2002 |
Ju YH, Doerge DR, Allred KF, Allred CD, Helferich WG. Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice Cancer Research. 62: 2474-2477. PMID 11980635 |
0.316 |
|
| 2001 |
Ju YH, Allred CD, Allred KF, Karko KL, Doerge DR, Helferich WG. Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice Journal of Nutrition. 131: 2957-2962. PMID 11694625 DOI: 10.1093/Jn/131.11.2957 |
0.435 |
|
| 2001 |
Allred CD, Ju YH, Allred KF, Chang J, Helferich WG. Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein Carcinogenesis. 22: 1667-1673. PMID 11577007 DOI: 10.1093/Carcin/22.10.1667 |
0.516 |
|
| 2000 |
Ju YH, Carlson KE, Sun J, Pathak D, Katzenellenbogen BS, Katzenellenbogen JA, Helferich WG. Estrogenic effects of extracts from cabbage, fermented cabbage, and acidified brussels sprouts on growth and gene expression of estrogen-dependent human breast cancer (MCF-7) cells. Journal of Agricultural and Food Chemistry. 48: 4628-34. PMID 11052710 DOI: 10.1021/Jf000164Z |
0.386 |
|
| 2000 |
Santell RC, Kieu N, Helferich WG. Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice. The Journal of Nutrition. 130: 1665-9. PMID 10867033 DOI: 10.1093/JN/130.7.1665 |
0.325 |
|
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