| Year |
Citation |
Score |
| 2019 |
Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570586 DOI: 10.1073/Pnas.1901893116 |
0.374 |
|
| 2018 |
Wang ET, Treacy D, Eichinger K, Struck A, Estabrook J, Olafson H, Wang TT, Bhatt K, Westbrook T, Sedehizadeh S, Ward A, Day J, Brook D, Berglund JA, Cooper T, et al. Transcriptome alterations in myotonic dystrophy skeletal muscle and heart. Human Molecular Genetics. PMID 30561649 DOI: 10.1093/Hmg/Ddy432 |
0.301 |
|
| 2018 |
Jenquin JR, Coonrod LA, Silverglate QA, Pellitier NA, Hale MA, Xia G, Nakamori M, Berglund JA. Furamidine Rescues Myotonic Dystrophy Type I Associated Mis-Splicing through Multiple Mechanisms. Acs Chemical Biology. PMID 30118588 DOI: 10.1021/acschembio.8b00646 |
0.56 |
|
| 2018 |
Hale MA, Richardson JI, Day RC, McConnell OL, Arboleda J, Wang ET, Berglund JA. An engineered RNA binding protein with improved splicing regulation. Nucleic Acids Research. PMID 29309648 DOI: 10.1093/Nar/Gkx1304 |
0.636 |
|
| 2017 |
deLorimier E, Hinman MN, Copperman J, Datta K, Guenza M, Berglund JA. Pseudouridine modification inhibits muscleblind-like 1 (MBNL1) binding to CCUG repeats and minimally structured RNA through reduced RNA flexibility. The Journal of Biological Chemistry. PMID 28130447 DOI: 10.1074/Jbc.M116.770768 |
0.691 |
|
| 2016 |
Oddo JC, Saxena T, McConnell OL, Berglund JA, Wang ET. Conservation of context-dependent splicing activity in distant Muscleblind homologs. Nucleic Acids Research. PMID 27557707 DOI: 10.1093/Nar/Gkw735 |
0.581 |
|
| 2015 |
Siboni RB, Nakamori M, Wagner SD, Struck AJ, Coonrod LA, Harriott SA, Cass DM, Tanner MK, Berglund JA. Actinomycin D Specifically Reduces Expanded CUG Repeat RNA in Myotonic Dystrophy Models. Cell Reports. PMID 26686629 DOI: 10.1016/J.Celrep.2015.11.028 |
0.416 |
|
| 2015 |
Siboni RB, Bodner MJ, Khalifa MM, Docter AG, Choi JY, Nakamori M, Haley MM, Berglund JA. Biological Efficacy and Toxicity of Diamidines in Myotonic Dystrophy Type 1 Models. Journal of Medicinal Chemistry. PMID 26103061 DOI: 10.1021/Acs.Jmedchem.5B00356 |
0.401 |
|
| 2014 |
deLorimier E, Coonrod LA, Copperman J, Taber A, Reister EE, Sharma K, Todd PK, Guenza MG, Berglund JA. Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model. Nucleic Acids Research. 42: 12768-78. PMID 25303993 DOI: 10.1093/Nar/Gku941 |
0.513 |
|
| 2014 |
Wagner SD, Berglund JA. Alternative pre-mRNA splicing. Methods in Molecular Biology (Clifton, N.J.). 1126: 45-54. PMID 24549655 DOI: 10.1007/978-1-62703-980-2_4 |
0.375 |
|
| 2013 |
Coonrod LA, Nakamori M, Wang W, Carrell S, Hilton CL, Bodner MJ, Siboni RB, Docter AG, Haley MM, Thornton CA, Berglund JA. Reducing levels of toxic RNA with small molecules. Acs Chemical Biology. 8: 2528-37. PMID 24028068 DOI: 10.1021/Cb400431F |
0.602 |
|
| 2013 |
Kannan R, Hartnett S, Voelker RB, Berglund JA, Staley JP, Baumann P. Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast. Genes & Development. 27: 627-38. PMID 23468430 DOI: 10.1101/gad.212738.112 |
0.688 |
|
| 2012 |
Coonrod LA, Lohman JR, Berglund JA. Utilizing the GAAA tetraloop/receptor to facilitate crystal packing and determination of the structure of a CUG RNA helix. Biochemistry. 51: 8330-7. PMID 23025897 DOI: 10.1021/Bi300829W |
0.539 |
|
| 2012 |
Purcell J, Oddo JC, Wang ET, Berglund JA. Combinatorial mutagenesis of MBNL1 zinc fingers elucidates distinct classes of regulatory events. Molecular and Cellular Biology. 32: 4155-67. PMID 22890842 DOI: 10.1128/Mcb.00274-12 |
0.646 |
|
| 2012 |
Voelker RB, Erkelenz S, Reynoso V, Schaal H, Berglund JA. Frequent gain and loss of intronic splicing regulatory elements during the evolution of vertebrates. Genome Biology and Evolution. 4: 659-74. PMID 22619362 DOI: 10.1093/gbe/evs051 |
0.405 |
|
| 2011 |
Gates DP, Coonrod LA, Berglund JA. Autoregulated splicing of muscleblind-like 1 (MBNL1) Pre-mRNA. The Journal of Biological Chemistry. 286: 34224-33. PMID 21832083 DOI: 10.1074/Jbc.M111.236547 |
0.658 |
|
| 2011 |
Cass D, Hotchko R, Barber P, Jones K, Gates DP, Berglund JA. The four Zn fingers of MBNL1 provide a flexible platform for recognition of its RNA binding elements. Bmc Molecular Biology. 12: 20. PMID 21548961 DOI: 10.1186/1471-2199-12-20 |
0.735 |
|
| 2010 |
Culler SJ, Hoff KG, Voelker RB, Berglund JA, Smolke CD. Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors. Nucleic Acids Research. 38: 5152-65. PMID 20385591 DOI: 10.1093/Nar/Gkq248 |
0.419 |
|
| 2010 |
Goers ES, Purcell J, Voelker RB, Gates DP, Berglund JA. MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing. Nucleic Acids Research. 38: 2467-84. PMID 20071745 DOI: 10.1093/Nar/Gkp1209 |
0.729 |
|
| 2010 |
Warf MB, Berglund JA. Role of RNA structure in regulating pre-mRNA splicing. Trends in Biochemical Sciences. 35: 169-78. PMID 19959365 DOI: 10.1016/j.tibs.2009.10.004 |
0.663 |
|
| 2009 |
Warf MB, Nakamori M, Matthys CM, Thornton CA, Berglund JA. Pentamidine reverses the splicing defects associated with myotonic dystrophy. Proceedings of the National Academy of Sciences of the United States of America. 106: 18551-6. PMID 19822739 DOI: 10.1073/pnas.0903234106 |
0.43 |
|
| 2009 |
Warf MB, Diegel JV, von Hippel PH, Berglund JA. The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing. Proceedings of the National Academy of Sciences of the United States of America. 106: 9203-8. PMID 19470458 DOI: 10.1073/pnas.0900342106 |
0.638 |
|
| 2008 |
Goers ES, Voelker RB, Gates DP, Berglund JA. RNA binding specificity of Drosophila muscleblind. Biochemistry. 47: 7284-94. PMID 18557632 DOI: 10.1021/Bi702252D |
0.765 |
|
| 2008 |
Murray JI, Voelker RB, Henscheid KL, Warf MB, Berglund JA. Identification of motifs that function in the splicing of non-canonical introns. Genome Biology. 9: R97. PMID 18549497 DOI: 10.1186/Gb-2008-9-6-R97 |
0.533 |
|
| 2008 |
Henscheid KL, Voelker RB, Berglund JA. Alternative modes of binding by U2AF65 at the polypyrimidine tract. Biochemistry. 47: 449-59. PMID 18067274 DOI: 10.1021/bi701240t |
0.617 |
|
| 2008 |
Garrey SM, Cass DM, Wandler AM, Scanlan MS, Berglund JA. Transposition of two amino acids changes a promiscuous RNA binding protein into a sequence-specific RNA binding protein. Rna (New York, N.Y.). 14: 78-88. PMID 18000034 DOI: 10.1261/Rna.633808 |
0.607 |
|
| 2007 |
Warf MB, Berglund JA. MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T. Rna (New York, N.Y.). 13: 2238-51. PMID 17942744 DOI: 10.1261/rna.610607 |
0.616 |
|
| 2007 |
Voelker RB, Berglund JA. A comprehensive computational characterization of conserved mammalian intronic sequences reveals conserved motifs associated with constitutive and alternative splicing. Genome Research. 17: 1023-33. PMID 17525134 DOI: 10.1101/gr.6017807 |
0.452 |
|
| 2006 |
Cass DM, Berglund JA. The SF3b155 N-terminal domain is a scaffold important for splicing. Biochemistry. 45: 10092-101. PMID 16906767 DOI: 10.1021/bi060429o |
0.575 |
|
| 2006 |
Garrey SM, Voelker R, Berglund JA. An extended RNA binding site for the yeast branch point-binding protein and the role of its zinc knuckle domains in RNA binding. The Journal of Biological Chemistry. 281: 27443-53. PMID 16861232 DOI: 10.1074/jbc.M603137200 |
0.654 |
|
| 2005 |
Mooers BH, Logue JS, Berglund JA. The structural basis of myotonic dystrophy from the crystal structure of CUG repeats. Proceedings of the National Academy of Sciences of the United States of America. 102: 16626-31. PMID 16269545 DOI: 10.1073/pnas.0505873102 |
0.712 |
|
| 2005 |
Henscheid KL, Shin DS, Cary SC, Berglund JA. The splicing factor U2AF65 is functionally conserved in the thermotolerant deep-sea worm Alvinella pompejana. Biochimica Et Biophysica Acta. 1727: 197-207. PMID 15777616 DOI: 10.1016/J.Bbaexp.2005.01.008 |
0.441 |
|
| 2003 |
Berglund JA. Expanding the structural repertoire of g-quadruplexes. Structure (London, England : 1993). 11: 1315-6. PMID 14604520 DOI: 10.1016/j.str.2003.10.008 |
0.387 |
|
| 2001 |
Peled-Zehavi H, Berglund JA, Rosbash M, Frankel AD. Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex. Molecular and Cellular Biology. 21: 5232-41. PMID 11438677 DOI: 10.1128/Mcb.21.15.5232-5241.2001 |
0.702 |
|
| 2001 |
Berglund JA, Rosbash M, Schultz SC. Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines. Rna (New York, N.Y.). 7: 682-91. PMID 11350032 DOI: 10.1017/S1355838201002187 |
0.732 |
|
| 1998 |
Berglund JA, Fleming ML, Rosbash M. The KH domain of the branchpoint sequence binding protein determines specificity for the pre-mRNA branchpoint sequence. Rna (New York, N.Y.). 4: 998-1006. PMID 9701290 DOI: 10.1017/S1355838298980499 |
0.708 |
|
| 1998 |
Berglund JA, Abovich N, Rosbash M. A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition. Genes & Development. 12: 858-67. PMID 9512519 |
0.747 |
|
| 1997 |
Berglund JA, Chua K, Abovich N, Reed R, Rosbash M. The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC. Cell. 89: 781-7. PMID 9182766 DOI: 10.1016/S0092-8674(00)80261-5 |
0.634 |
|
| 1997 |
Berglund JA, Charpentier B, Rosbash M. A high affinity binding site for the HIV-1 nucleocapsid protein. Nucleic Acids Research. 25: 1042-9. PMID 9023116 DOI: 10.1093/Nar/25.5.1042 |
0.666 |
|
| 1996 |
Lietzke SE, Barnes CL, Berglund JA, Kundrot CE. The structure of an RNA dodecamer shows how tandem U-U base pairs increase the range of stable RNA structures and the diversity of recognition sites. Structure (London, England : 1993). 4: 917-30. PMID 8805576 DOI: 10.1016/S0969-2126(96)00099-8 |
0.548 |
|
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