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Yong Lei, Ph.D. - Publications

Affiliations: 
2013 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Genetics, Molecular Biology, General Biology
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lei Y, Huang YH, Goodell MA. DNA methylation and de-methylation using hybrid site-targeting proteins. Genome Biology. 19: 187. PMID 30400938 DOI: 10.1186/S13059-018-1566-2  0.345
2018 Su J, Huang YH, Cui X, Wang X, Zhang X, Lei Y, Xu J, Lin X, Chen K, Lv J, Goodell MA, Li W. Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biology. 19: 108. PMID 30097071 DOI: 10.1186/S13059-018-1492-3  0.313
2018 Jeong M, Park HJ, Celik H, Ostrander EL, Reyes JM, Guzman A, Rodriguez B, Lei Y, Lee Y, Ding L, Guryanova OA, Li W, Goodell MA, Challen GA. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo. Cell Reports. 23: 1-10. PMID 29617651 DOI: 10.1016/J.Celrep.2018.03.025  0.306
2018 Lei Y, Goodell MA. Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells Blood. 132: 2571-2571. DOI: 10.1182/Blood-2018-99-116841  0.372
2017 Huang YH, Su J, Lei Y, Brunetti L, Gundry MC, Zhang X, Jeong M, Li W, Goodell MA. DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A. Genome Biology. 18: 176. PMID 28923089 DOI: 10.1186/S13059-017-1306-Z  0.338
2017 Lei Y, Zhang X, Su J, Jeong M, Gundry MC, Huang YH, Zhou Y, Li W, Goodell MA. Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nature Communications. 8: 16026. PMID 28695892 DOI: 10.1038/Ncomms16026  0.345
2016 Zhang X, Su J, Jeong M, Ko M, Huang Y, Park HJ, Guzman A, Lei Y, Huang YH, Rao A, Li W, Goodell MA. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nature Genetics. PMID 27428748 DOI: 10.1038/Ng.3610  0.326
2016 Liu Z, Cheng TT, Shi Z, Liu Z, Lei Y, Wang C, Shi W, Chen X, Qi X, Cai D, Feng B, Deng Y, Chen Y, Zhao H. Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos. Cell & Bioscience. 6: 22. PMID 27042291 DOI: 10.1186/S13578-016-0088-4  0.327
2014 Liu Y, Luo D, Lei Y, Hu W, Zhao H, Cheng CH. A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish. Methods (San Diego, Calif.). 69: 58-66. PMID 24556556 DOI: 10.1016/J.Ymeth.2014.02.011  0.331
2014 Hu J, Lei Y, Wong WK, Liu S, Lee KC, He X, You W, Zhou R, Guo JT, Chen X, Peng X, Sun H, Huang H, Zhao H, Feng B. Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Research. 42: 4375-90. PMID 24500196 DOI: 10.1093/Nar/Gku109  0.346
2013 Lei Y, Guo X, Deng Y, Chen Y, Zhao H. Generation of gene disruptions by transcription activator-like effector nucleases (TALENs) in Xenopus tropicalis embryos. Cell & Bioscience. 3: 21. PMID 23663889 DOI: 10.1186/2045-3701-3-21  0.367
2012 Lei Y, Guo X, Liu Y, Cao Y, Deng Y, Chen X, Cheng CH, Dawid IB, Chen Y, Zhao H. Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proceedings of the National Academy of Sciences of the United States of America. 109: 17484-9. PMID 23045671 DOI: 10.1073/Pnas.1215421109  0.336
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