| Year |
Citation |
Score |
| 2023 |
Spangenberg SH, Palermo A, Gazaniga NR, Martínez-Peña F, Guijas C, Chin EN, Rinschen MM, Sander PN, Webb B, Pereira LE, Jia Y, Meitz L, Siuzdak G, Lairson LL. Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux. Cell Chemical Biology. PMID 37467751 DOI: 10.1016/j.chembiol.2023.06.016 |
0.643 |
|
| 2022 |
Chin EN, Sulpizio A, Lairson LL. Targeting STING to promote antitumor immunity. Trends in Cell Biology. PMID 35931610 DOI: 10.1016/j.tcb.2022.06.010 |
0.686 |
|
| 2020 |
Chin EN, Yu C, Vartabedian VF, Jia Y, Kumar M, Gamo AM, Vernier W, Ali SH, Kissai M, Lazar DC, Nguyen N, Pereira LE, Benish B, Woods AK, Joseph SB, et al. Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.). 369: 993-999. PMID 32820126 DOI: 10.1126/Science.Abb4255 |
0.63 |
|
| 2020 |
Vinogradova EV, Zhang X, Remillard D, Lazar DC, Suciu RM, Wang Y, Bianco G, Yamashita Y, Crowley VM, Schafroth MA, Yokoyama M, Konrad DB, Lum KM, Simon GM, Kemper EK, ... ... Chin EN, et al. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. PMID 32730809 DOI: 10.1016/J.Cell.2020.07.001 |
0.671 |
|
| 2020 |
Huffman BJ, Chen S, Schwarz JL, Plata RE, Chin EN, Lairson LL, Houk KN, Shenvi RA. Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonists. Nature Chemistry. PMID 32042135 DOI: 10.1038/S41557-019-0413-8 |
0.608 |
|
| 2019 |
Lucki NC, Villa GR, Vergani N, Bollong MJ, Beyer BA, Lee JW, Anglin JL, Spangenberg SH, Chin EN, Sharma A, Johnson K, Sander PN, Gordon P, Skirboll SL, Wurdak H, et al. A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 30846550 DOI: 10.1073/Pnas.1816626116 |
0.561 |
|
| 2018 |
Bollong MJ, Lee G, Coukos JS, Yun H, Zambaldo C, Chang JW, Chin EN, Ahmad I, Chatterjee AK, Lairson LL, Schultz PG, Moellering RE. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. PMID 30323285 DOI: 10.1038/S41586-018-0622-0 |
0.678 |
|
| 2017 |
Bollong MJ, Yang B, Vergani N, Beyer BA, Chin EN, Zambaldo C, Wang D, Chatterjee AK, Lairson LL, Schultz PG. Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 114: 4679-4684. PMID 28416697 DOI: 10.1073/Pnas.1702750114 |
0.702 |
|
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