Philip O. Scumpia, Ph.D. - Publications

Affiliations: 
2007 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Immunology, Medicine and Surgery, Pathology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hsieh WY, Zhou QD, York AG, Williams KJ, Scumpia PO, Kronenberger EB, Hoi XP, Su B, Chi X, Bui VL, Khialeeva E, Kaplan A, Son YM, Divakaruni AS, Sun J, et al. Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome. Cell Metabolism. PMID 32516576 DOI: 10.1016/J.Cmet.2020.05.003  0.334
2020 Kelly-Scumpia KM, Choi A, Shirazi R, Bersabe H, Park E, Scumpia PO, Ochoa MT, Yu J, Ma F, Pellegrini M, Modlin RL. ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ. Iscience. 23: 101050. PMID 32339990 DOI: 10.1016/J.Isci.2020.101050  0.425
2019 Koh J, Griffin DR, Archang MM, Feng AC, Horn T, Margolis M, Zalazar D, Segura T, Scumpia PO, Di Carlo D. Enhanced In Vivo Delivery of Stem Cells using Microporous Annealed Particle Scaffolds. Small (Weinheim An Der Bergstrasse, Germany). e1903147. PMID 31410986 DOI: 10.1002/Smll.201903147  0.314
2018 Keegan C, Krutzik S, Schenk M, Scumpia PO, Lu J, Pang YLJ, Russell BS, Lim KS, Shell S, Prestwich E, Su D, Elashoff D, Hershberg RM, Bloom BR, Belisle JT, et al. Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network. Journal of Immunology (Baltimore, Md. : 1950). PMID 29610140 DOI: 10.4049/Jimmunol.1701733  0.457
2017 Moon H, Donahue LR, Choi E, Scumpia PO, Lowry WE, Grenier JK, Zhu J, White AC. Melanocyte Stem Cell Activation and Translocation Initiate Cutaneous Melanoma in Response to UV Exposure. Cell Stem Cell. PMID 29033353 DOI: 10.1016/J.Stem.2017.09.001  0.306
2017 Song C, Piva M, Sun L, Hong A, Moriceau G, Kong X, Zhang H, Lomeli S, Qian J, Yu CC, Damoiseaux R, Kelley MC, Dahlman KB, Scumpia PO, Sosman JA, et al. Recurrent tumor cell-intrinsic and -extrinsic alterations during MAPKi-induced melanoma regression and early adaptation. Cancer Discovery. PMID 28864476 DOI: 10.1158/2159-8290.Cd-17-0401  0.35
2017 Scumpia PO, Botten GA, Norman JS, Kelly-Scumpia KM, Spreafico R, Ruccia AR, Purbey PK, Thomas BJ, Modlin RL, Smale ST. Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense. Plos Pathogens. 13: e1006496. PMID 28704551 DOI: 10.1371/Journal.Ppat.1006496  0.351
2016 Wynn JL, Wilson CS, Hawiger J, Scumpia PO, Marshall AF, Liu JH, Zharkikh I, Wong HR, Lahni P, Benjamin JT, Plosa EJ, Weitkamp JH, Sherwood ER, Moldawer LL, Ungaro R, et al. Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114524 DOI: 10.1073/Pnas.1515793113  0.384
2015 Wynn JL, Scumpia PO, Stocks BT, Romano-Keeler J, Alrifai MW, Liu JH, Kim AS, Alford CE, Matta P, Weitkamp JH, Moore DJ. Neonatal CD71+ Erythroid Cells Do Not Modify Murine Sepsis Mortality. Journal of Immunology (Baltimore, Md. : 1950). PMID 26101326 DOI: 10.4049/Jimmunol.1500771  0.339
2015 Cuenca AG, Joiner DN, Gentile LF, Cuenca AL, Wynn JL, Kelly-Scumpia KM, Scumpia PO, Behrns KE, Efron PA, Nacionales D, Lui C, Wallet SM, Reeves WH, Mathews CE, Moldawer LL. TRIF-dependent innate immune activation is critical for survival to neonatal gram-negative sepsis. Journal of Immunology (Baltimore, Md. : 1950). 194: 1169-77. PMID 25548220 DOI: 10.4049/Jimmunol.1302676  0.318
2014 Cuenca AG, Cuenca AL, Winfield RD, Joiner DN, Gentile L, Delano MJ, Kelly-Scumpia KM, Scumpia PO, Matheny MK, Scarpace PJ, Vila L, Efron PA, LaFace DM, Moldawer LL. Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia. Journal of Immunology (Baltimore, Md. : 1950). 192: 6111-9. PMID 24829407 DOI: 10.4049/Jimmunol.1302895  0.352
2014 Scumpia PO, Kelly-Scumpia K, Stevens BR. Alpha-lipoic acid effects on brain glial functions accompanying double-stranded RNA antiviral and inflammatory signaling. Neurochemistry International. 64: 55-63. PMID 24269587 DOI: 10.1016/J.Neuint.2013.11.006  0.35
2013 Weinstein JS, Delano MJ, Xu Y, Kelly-Scumpia KM, Nacionales DC, Li Y, Lee PY, Scumpia PO, Yang L, Sobel E, Moldawer LL, Reeves WH. Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 3916-27. PMID 23509349 DOI: 10.4049/Jimmunol.1201880  0.358
2011 Kelly-Scumpia KM, Scumpia PO, Weinstein JS, Delano MJ, Cuenca AG, Nacionales DC, Wynn JL, Lee PY, Kumagai Y, Efron PA, Akira S, Wasserfall C, Atkinson MA, Moldawer LL. B cells enhance early innate immune responses during bacterial sepsis. The Journal of Experimental Medicine. 208: 1673-82. PMID 21746813 DOI: 10.1084/Jem.20101715  0.416
2011 Cuenca AG, Wynn JL, Kelly-Scumpia KM, Scumpia PO, Vila L, Delano MJ, Mathews CE, Wallet SM, Reeves WH, Behrns KE, Nacionales DC, Efron PA, Kunkel SL, Moldawer LL. Critical role for CXC ligand 10/CXC receptor 3 signaling in the murine neonatal response to sepsis. Infection and Immunity. 79: 2746-54. PMID 21518789 DOI: 10.1128/Iai.01291-10  0.369
2011 Delano MJ, Thayer T, Gabrilovich S, Kelly-Scumpia KM, Winfield RD, Scumpia PO, Cuenca AG, Warner E, Wallet SM, Wallet MA, O'Malley KA, Ramphal R, Clare-Salzer M, Efron PA, Mathews CE, et al. Sepsis induces early alterations in innate immunity that impact mortality to secondary infection. Journal of Immunology (Baltimore, Md. : 1950). 186: 195-202. PMID 21106855 DOI: 10.4049/Jimmunol.1002104  0.359
2011 Cuenca AG, Delano MJ, Kelly-Scumpia KM, Moreno C, Scumpia PO, Laface DM, Heyworth PG, Efron PA, Moldawer LL. A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Molecular Medicine (Cambridge, Mass.). 17: 281-92. PMID 21085745 DOI: 10.2119/Molmed.2010.00178  0.437
2010 Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, Al-Quran S, Bovio I, Akira S, Kumagai Y, Moldawer LL. Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 2247-51. PMID 20130216 DOI: 10.4049/Jimmunol.0903652  0.397
2010 Kelly-Scumpia KM, Scumpia PO, Delano MJ, Weinstein JS, Cuenca AG, Wynn JL, Moldawer LL. Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10. The Journal of Experimental Medicine. 207: 319-26. PMID 20071504 DOI: 10.1084/Jem.20091959  0.376
2009 Efron PA, Matsumoto T, McAuliffe PF, Scumpia P, Ungaro R, Fujita S, Moldawer LL, Foley D, Hemming AW. Major hepatectomy induces phenotypic changes in circulating dendritic cells and monocytes. Journal of Clinical Immunology. 29: 568-81. PMID 19387804 DOI: 10.1007/S10875-009-9291-Y  0.322
2008 Winfield RD, Delano MJ, Pande K, Scumpia PO, Laface D, Moldawer LL. Myeloid-derived suppressor cells in cancer cachexia syndrome: a new explanation for an old problem. Jpen. Journal of Parenteral and Enteral Nutrition. 32: 651-5. PMID 18974247 DOI: 10.1177/0148607108325075  0.353
2008 Weinstein JS, Nacionales DC, Lee PY, Kelly-Scumpia KM, Yan XJ, Scumpia PO, Vale-Cruz DS, Sobel E, Satoh M, Chiorazzi N, Reeves WH. Colocalization of antigen-specific B and T cells within ectopic lymphoid tissue following immunization with exogenous antigen. Journal of Immunology (Baltimore, Md. : 1950). 181: 3259-67. PMID 18713997 DOI: 10.4049/Jimmunol.181.5.3259  0.391
2008 Wynn JL, Scumpia PO, Winfield RD, Delano MJ, Kelly-Scumpia K, Barker T, Ungaro R, Levy O, Moldawer LL. Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood. 112: 1750-8. PMID 18591384 DOI: 10.1182/Blood-2008-01-130500  0.387
2008 Lee PY, Weinstein JS, Nacionales DC, Scumpia PO, Li Y, Butfiloski E, van Rooijen N, Moldawer L, Satoh M, Reeves WH. A novel type I IFN-producing cell subset in murine lupus. Journal of Immunology (Baltimore, Md. : 1950). 180: 5101-8. PMID 18354236 DOI: 10.4049/Jimmunol.180.7.5101  0.378
2008 Tsujimoto H, Ono S, Efron PA, Scumpia PO, Moldawer LL, Mochizuki H. Role of Toll-like receptors in the development of sepsis. Shock (Augusta, Ga.). 29: 315-21. PMID 18277854 DOI: 10.1097/Shk.0B013E318157Ee55  0.348
2008 Caicedo RA, Li N, Des Robert C, Scumpia PO, Hubsher CP, Wasserfall CH, Schatz DA, Atkinson MA, Neu J. Neonatal formula feeding leads to immunological alterations in an animal model of type 1 diabetes. Pediatric Research. 63: 303-7. PMID 18091354 DOI: 10.1203/Pdr.0B013E31815Ed662  0.39
2007 Kelly-Scumpia KM, Nacionales DC, Scumpia PO, Weinstein JS, Narain S, Moldawer LL, Satoh M, Reeves WH. In vivo adjuvant activity of the RNA component of the Sm/RNP lupus autoantigen. Arthritis and Rheumatism. 56: 3379-86. PMID 17907192 DOI: 10.1002/Art.22946  0.354
2007 Scumpia PO, Delano MJ, Kelly-Scumpia KM, Weinstein JS, Wynn JL, Winfield RD, Xia C, Chung CS, Ayala A, Atkinson MA, Reeves WH, Clare-Salzler MJ, Moldawer LL. Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood. 110: 3673-81. PMID 17690255 DOI: 10.1182/Blood-2007-04-087171  0.629
2007 Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, Kelly-Scumpia KM, O'Malley KA, Wynn JL, Antonenko S, Al-Quran SZ, Swan R, Chung CS, Atkinson MA, Ramphal R, Gabrilovich DI, et al. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. The Journal of Experimental Medicine. 204: 1463-74. PMID 17548519 DOI: 10.1084/Jem.20062602  0.643
2007 Uchida T, Scumpia PO, Murasko DM, Seki S, Woulfe S, Clare-Salzler MJ, Moldawer LL. Variable requirement of dendritic cells for recruitment of NK and T cells to different TLR agonists. Journal of Immunology (Baltimore, Md. : 1950). 178: 3886-92. PMID 17339488 DOI: 10.4049/Jimmunol.178.6.3886  0.641
2006 Scumpia PO, Delano MJ, Kelly KM, O'Malley KA, Efron PA, McAuliffe PF, Brusko T, Ungaro R, Barker T, Wynn JL, Atkinson MA, Reeves WH, Salzler MJ, Moldawer LL. Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 177: 7943-9. PMID 17114466 DOI: 10.4049/Jimmunol.177.11.7943  0.394
2006 Matsumoto T, O'Malley K, Efron PA, Burger C, McAuliffe PF, Scumpia PO, Uchida T, Tschoeke SK, Fujita S, Moldawer LL, Hemming AW, Foley DP. Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioning. Surgery. 140: 793-802. PMID 17084723 DOI: 10.1016/J.Surg.2006.04.010  0.332
2006 Kelly KM, Zhuang H, Nacionales DC, Scumpia PO, Lyons R, Akaogi J, Lee P, Williams B, Yamamoto M, Akira S, Satoh M, Reeves WH. "Endogenous adjuvant" activity of the RNA components of lupus autoantigens Sm/RNP and Ro 60. Arthritis and Rheumatism. 54: 1557-67. PMID 16645989 DOI: 10.1002/Art.21819  0.335
2006 McAuliffe PF, Murday ME, Efron PA, Scumpia PO, Ungaro R, Abouhamze A, Tannahill CL, Hutchins B, LaFace D, Moldawer LL. Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure Gene Therapy. 13: 276-282. PMID 16251998 DOI: 10.1038/Sj.Gt.3302600  0.365
2006 Delano M, Scumpia P, O'Malley K, Wynn J, Ungaro R, Moldawer L. Regulation Of Gr-1+Cd11B+ Myeloid Suppressor Cells In Murine Polymicrobial Sepsis Shock. 25: 64-65. DOI: 10.1097/00024382-200606001-00195  0.367
2006 Scumpia P, Delano M, Moldawer L. Regulatory T Cells Are Increased But Do Not Participate In Mortality In Murine Polymicrobial Sepsis Shock. 25: 8-9. DOI: 10.1097/00024382-200606001-00025  0.322
2005 Scumpia PO, McAuliffe PF, O'Malley KA, Ungaro R, Uchida T, Matsumoto T, Remick DG, Clare-Salzler MJ, Moldawer LL, Efron PA. CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis. Journal of Immunology (Baltimore, Md. : 1950). 175: 3282-6. PMID 16116220 DOI: 10.4049/Jimmunol.175.5.3282  0.616
2005 Tsujimoto H, Uchida T, Efron PA, Scumpia PO, Verma A, Matsumoto T, Tschoeke SK, Ungaro RF, Ono S, Seki S, Clare-Salzler MJ, Baker HV, Mochizuki H, Ramphal R, Moldawer LL. Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions. Journal of Leukocyte Biology. 78: 888-97. PMID 16033815 DOI: 10.1189/Jlb.0105051  0.641
2005 Scumpia PO, Kelly KM, Reeves WH, Stevens BR. Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes Glia. 52: 153-162. PMID 15920723 DOI: 10.1002/Glia.20234  0.353
2005 Oberholzer A, Oberholzer C, Efron PA, Scumpia PO, Uchida T, Bahjat K, Ungaro R, Tannahill CL, Murday M, Bahjat FR, Tsai V, Hutchins B, Moldawer LL, Laface D, Clare-Salzler MJ. Functional modification of dendritic cells with recombinant adenovirus encoding interleukin 10 for the treatment of sepsis. Shock (Augusta, Ga.). 23: 507-15. PMID 15897802 DOI: 10.1097/01.Shk.0000163208.29655.74  0.665
2005 Liboni KC, Li N, Scumpia PO, Neu J. Glutamine modulates LPS-induced IL-8 production through IkappaB/NF-kappaB in human fetal and adult intestinal epithelium. The Journal of Nutrition. 135: 245-51. PMID 15671221 DOI: 10.1093/Jn/135.2.245  0.385
2004 Efron PA, Scumpia PO, Matsumoto T, Ungaro R, Moldawer LL. T Regulatory Cells Are Increased During Murine Polymicrobial Sepsis: 209 Shock. 21: 53. DOI: 10.1097/00024382-200403001-00209  0.352
2003 Sarcia PJ, Scumpia PO, Moldawer LL, DeMarco VG, Skimming JW. Hypothermia induces interleukin-10 and attenuates injury in the lungs of endotoxemic rats. Shock (Augusta, Ga.). 20: 41-5. PMID 12813367 DOI: 10.1097/01.Shk.0000071080.50028.F2  0.362
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