Holly Shiels - Publications

Affiliations: 
University of Manchester, Manchester, England, United Kingdom 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Galli GLJ, Shiels HA, White E, Couturier CS, Stecyk JAW. The air-breathing Alaska blackfish (Dallia pectoralis) suppresses brain mitochondrial reactive oxygen species to survive cold hypoxic winters. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 276: 111355. PMID 36529208 DOI: 10.1016/j.cbpa.2022.111355  0.638
2022 Shiels HA. Avian cardiomyocyte architecture and what it reveals about the evolution of the vertebrate heart. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 377: 20210332. PMID 36189815 DOI: 10.1098/rstb.2021.0332  0.374
2022 Abramochkin DV, Haworth TE, Kuzmin VS, Dzhumaniiazova I, Pustovit KB, Gacoin M, Shiels HA. Adrenergic prolongation of action potential duration in rainbow trout myocardium via inhibition of the delayed rectifier potassium current, I. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 267: 111161. PMID 35143950 DOI: 10.1016/j.cbpa.2022.111161  0.306
2022 Shiels HA, White E, Couturier CS, Hall D, Royal S, Galli GLJ, Stecyk JAW. The air-breathing Alaska blackfish () remodels ventricular Ca cycling with chronic hypoxic submergence to maintain ventricular contractility. Current Research in Physiology. 5: 25-35. PMID 35072107 DOI: 10.1016/j.crphys.2022.01.001  0.736
2021 Keen AN, Mackrill JJ, Gardner P, Shiels HA. Compliance of the fish outflow tract is altered by thermal acclimation through connective tissue remodelling. Journal of the Royal Society, Interface. 18: 20210492. PMID 34784777 DOI: 10.1098/rsif.2021.0492  0.781
2021 Schwieterman GD, Winchester MM, Shiels HA, Bushnell PG, Bernal D, Marshall HM, Brill RW. The effects of elevated potassium, acidosis, reduced oxygen levels, and temperature on the functional properties of isolated myocardium from three elasmobranch fishes: clearnose skate (Rostroraja eglanteria), smooth dogfish (Mustelus canis), and sandbar shark (Carcharhinus plumbeus). Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. PMID 33394123 DOI: 10.1007/s00360-020-01328-8  0.313
2020 Ainerua MO, Tinwell J, Murphy R, Galli GLJ, van Dongen BE, White KN, Shiels HA. Prolonged phenanthrene exposure reduces cardiac function but fails to mount a significant oxidative stress response in the signal crayfish (Pacifastacus leniusculus). Chemosphere. 268: 129297. PMID 33359987 DOI: 10.1016/j.chemosphere.2020.129297  0.668
2020 Filatova TS, Abramochkin DV, Shiels HA. Warmer, faster, stronger: Ca cycling in avian myocardium. The Journal of Experimental Biology. PMID 32843363 DOI: 10.1242/jeb.228205  0.337
2019 Ainerua MO, Tinwell J, Kompella SN, Sørhus E, White KN, van Dongen BE, Shiels HA. Understanding the cardiac toxicity of the anthropogenic pollutant phenanthrene on the freshwater indicator species, the brown trout (Salmo trutta): From whole heart to cardiomyocytes. Chemosphere. 239: 124608. PMID 31499312 DOI: 10.1016/J.Chemosphere.2019.124608  0.367
2019 Heuer RM, Galli GLJ, Shiels HA, Fieber LA, Cox GK, Mager E, Stieglitz JD, Benetti DD, Grosell M, Crossley DA. Impacts of crude oil on mahi-mahi () heart cell function. Environmental Science & Technology. PMID 31343865 DOI: 10.1021/Acs.Est.9B03798  0.654
2019 Filatova TS, Abramochkin DV, Shiels HA. Thermal acclimation and seasonal acclimatization: a comparative study of cardiac response to prolonged temperature change in shorthorn sculpin. The Journal of Experimental Biology. PMID 31315933 DOI: 10.1242/jeb.202242  0.343
2019 Ruhr IM, McCourty H, Bajjig A, Crossley DA, Shiels HA, Galli GLJ. Developmental plasticity of cardiac anoxia-tolerance in juvenile common snapping turtles ( Chelydra serpentina). Proceedings. Biological Sciences. 286: 20191072. PMID 31238852 DOI: 10.1098/rspb.2019.1072  0.701
2019 Sheard TMD, Kharche SR, Pinali C, Shiels HA. 3D ultrastructural organisation of calcium release units in the avian sarcoplasmic reticulum. The Journal of Experimental Biology. PMID 30814295 DOI: 10.1242/jeb.197640  0.306
2018 Keen AN, Fenna AJ, McConnell JC, Sherratt MJ, Gardner P, Shiels HA. Macro- and micromechanical remodelling in the fish atrium is associated with regulation of collagen 1 alpha 3 chain expression. Pflugers Archiv : European Journal of Physiology. PMID 29594338 DOI: 10.1007/s00424-018-2140-1  0.787
2017 Brette F, Shiels HA, Galli GL, Cros C, Incardona JP, Scholz NL, Block BA. A Novel Cardiotoxic Mechanism for a Pervasive Global Pollutant. Scientific Reports. 7: 41476. PMID 28139666 DOI: 10.1038/srep41476  0.727
2016 Keen AN, Klaiman JM, Shiels HA, Gillis TE. Temperature-induced cardiac remodeling in fish. The Journal of Experimental Biology. PMID 27852752 DOI: 10.1242/Jeb.128496  0.812
2016 Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA. Developmental Plasticity of Mitochondrial Function in American Alligators, Alligator mississippiensis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00107.2016. PMID 27707718 DOI: 10.1152/ajpregu.00107.2016  0.652
2016 Ozolina K, Shiels HA, Ollivier H, Claireaux G. Intraspecific individual variation of temperature tolerance associated with oxygen demand in the European sea bass (Dicentrarchus labrax). Conservation Physiology. 4: cov060. PMID 27382468 DOI: 10.1093/conphys/cov060  0.301
2016 Keen AN, Shiels HA, Crossley DA. Cardiovascular function, compliance, and connective tissue remodeling in the turtle, Trachemys scripta, following thermal acclimation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 311: R133-43. PMID 27101300 DOI: 10.1152/ajpregu.00510.2015  0.775
2016 Joyce W, Ozolina K, Mauduit F, Ollivier H, Claireaux G, Shiels HA. Individual variation in whole-animal hypoxia tolerance is associated with cardiac hypoxia tolerance in a marine teleost. Biology Letters. 12: 20150708. PMID 26740561 DOI: 10.1098/rsbl.2015.0708  0.311
2016 Lea JM, Keen AN, Nudds RL, Shiels HA. Kinematics and energetics of swimming performance during acute warming in brown trout Salmo trutta. Journal of Fish Biology. 88: 403-17. PMID 26563644 DOI: 10.1111/Jfb.12788  0.77
2016 Keen AN, Fenna AJ, McConnell JC, Sherratt MJ, Gardner P, Shiels HA. The dynamic nature of hypertrophic and fibrotic remodeling of the fish ventricle Frontiers in Physiology. 6. DOI: 10.3389/fphys.2015.00427  0.8
2015 Keen AN, Fenna AJ, McConnell JC, Sherratt MJ, Gardner P, Shiels HA. The Dynamic Nature of Hypertrophic and Fibrotic Remodeling of the Fish Ventricle. Frontiers in Physiology. 6: 427. PMID 26834645 DOI: 10.3389/fphys.2015.00427  0.8
2015 Shiels HA, Sitsapesan R. Is there something fishy about the regulation of the ryanodine receptor in the fish heart? Experimental Physiology. 100: 1412-20. PMID 26206750 DOI: 10.1113/EP085136  0.392
2015 Shiels HA, Galli GL, Block BA. Cardiac function in an endothermic fish: cellular mechanisms for overcoming acute thermal challenges during diving. Proceedings. Biological Sciences / the Royal Society. 282: 20141989. PMID 25540278 DOI: 10.1098/rspb.2014.1989  0.777
2014 Shiels HA, Galli GL. The sarcoplasmic reticulum and the evolution of the vertebrate heart. Physiology (Bethesda, Md.). 29: 456-69. PMID 25362639 DOI: 10.1152/physiol.00015.2014  0.679
2014 Haworth TE, Haverinen J, Shiels HA, Vornanen M. Electrical excitability of the heart in a Chondrostei fish, the Siberian sturgeon (Acipenser baerii). American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R1157-66. PMID 25163915 DOI: 10.1152/ajpregu.00253.2014  0.318
2014 Nudds RL, John EL, Keen AN, Shiels HA. Rainbow trout provide the first experimental evidence for adherence to a distinct Strouhal number during animal oscillatory propulsion. The Journal of Experimental Biology. 217: 2244-9. PMID 25141343 DOI: 10.1242/jeb.102236  0.742
2011 Klaiman JM, Fenna AJ, Shiels HA, Macri J, Gillis TE. Cardiac remodeling in fish: strategies to maintain heart function during temperature Change. Plos One. 6: e24464. PMID 21915331 DOI: 10.1371/Journal.Pone.0024464  0.409
2011 Patrick SM, White E, Shiels HA. Rainbow trout myocardium does not exhibit a slow inotropic response to stretch. The Journal of Experimental Biology. 214: 1118-22. PMID 21389196 DOI: 10.1242/jeb.048546  0.31
2011 Galli GL, Lipnick MS, Shiels HA, Block BA. Temperature effects on Ca2+ cycling in scombrid cardiomyocytes: a phylogenetic comparison. The Journal of Experimental Biology. 214: 1068-76. PMID 21389190 DOI: 10.1242/jeb.048231  0.746
2011 Shiels HA, Di Maio A, Thompson S, Block BA. Warm fish with cold hearts: thermal plasticity of excitation-contraction coupling in bluefin tuna. Proceedings. Biological Sciences / the Royal Society. 278: 18-27. PMID 20667881 DOI: 10.1098/rspb.2010.1274  0.652
2011 Cros C, Salle L, Warren D, Shiels H, Brette F. Calcium Stored in the Sarcoplasmic Reticulum Acts as a Safety Mechanism in Fish Heart Biophysical Journal. 100: 290a. DOI: 10.1016/J.Bpj.2010.12.1786  0.336
2010 Shiels HA, Santiago DA, Galli GL. Hypercapnic acidosis reduces contractile function in the ventricle of the armored catfish, Pterygoplichthys pardalis. Physiological and Biochemical Zoology : Pbz. 83: 366-75. PMID 20113172 DOI: 10.1086/644759  0.659
2010 Warren DE, Galli GL, Patrick SM, Shiels HA. The cellular force-frequency response in ventricular myocytes from the varanid lizard, Varanus exanthematicus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 298: R567-74. PMID 20053961 DOI: 10.1152/ajpregu.00650.2009  0.693
2009 Galli GL, Warren DE, Shiels HA. Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1636-44. PMID 19812356 DOI: 10.1152/ajpregu.00381.2009  0.691
2009 Birkedal R, Christopher J, Thistlethwaite A, Shiels HA. Temperature acclimation has no effect on ryanodine receptor expression or subcellular localization in rainbow trout heart. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 179: 961-9. PMID 19544062 DOI: 10.1007/s00360-009-0377-x  0.751
2009 Galli GL, Shiels HA, Brill RW. Temperature sensitivity of cardiac function in pelagic fishes with different vertical mobilities: yellowfin tuna (Thunnus albacares), bigeye tuna (Thunnus obesus), mahimahi (Coryphaena hippurus), and swordfish (Xiphias gladius). Physiological and Biochemical Zoology : Pbz. 82: 280-90. PMID 19284308 DOI: 10.1086/597484  0.714
2009 Patrick S, Shiels H, Cazorla O. J001 Comparison of length-dependent Ca2+ activation of cardiac myofilaments between the rat and the rainbow trout Archives of Cardiovascular Diseases. 102: S102. DOI: 10.1016/S1875-2136(09)72376-9  0.47
2009 Galli GL, Warren D, Shiels HA. Specialisations in excitation–contraction coupling contribute to high cardiovascular performance in varanid lizards Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 153: S97. DOI: 10.1016/j.cbpa.2009.04.113  0.596
2009 Warren DE, Galli GL, Patrick S, Shiels HA. Cellular investigation into the negative-force frequency response in ventricular myocytes from the varanid lizard Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 153: S97. DOI: 10.1016/j.cbpa.2009.04.112  0.651
2008 Stecyk JA, Galli GL, Shiels HA, Farrell AP. Cardiac survival in anoxia-tolerant vertebrates: An electrophysiological perspective. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 148: 339-54. PMID 18589002 DOI: 10.1016/j.cbpc.2008.05.016  0.748
2008 Shiels HA, White E. The Frank-Starling mechanism in vertebrate cardiac myocytes. The Journal of Experimental Biology. 211: 2005-13. PMID 18552289 DOI: 10.1242/jeb.003145  0.374
2008 Patrick S, Shiels H, White E. The presence of mechanosensitive channels in the rainbow trout (Oncorhynchus mykiss) heart Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 150: S98. DOI: 10.1016/J.Cbpa.2008.04.195  0.315
2008 Galli G, Lipnick M, Shiels H, Block B. Thermal plasticity of excitation–contraction coupling in bluefin tuna myocytes Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 150: S98. DOI: 10.1016/J.Cbpa.2008.04.194  0.695
2007 Birkedal R, Shiels HA. High [Na+]i in cardiomyocytes from rainbow trout. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R861-6. PMID 17507438 DOI: 10.1152/ajpregu.00198.2007  0.737
2007 Shiels H, O'Connell A, Qureshi MA, Howarth FC, White E, Calaghan S. Stable microtubules contribute to cardiac dysfunction in the streptozotocin-induced model of type 1 diabetes in the rat. Molecular and Cellular Biochemistry. 294: 173-80. PMID 16838107 DOI: 10.1007/S11010-006-9257-9  0.387
2007 Patrick S, White E, Brill R, Shiels H. 35.P5. The effect of heart rate on the monophasic action potential recorded in isolated yellowfin tuna (Thunnus albacares) cardiac muscle Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 148: S153. DOI: 10.1016/J.Cbpa.2007.06.388  0.371
2007 Patrick S, White E, Shiels H. 35.P4. The effect of stretch on the electrical activity of the rainbow trout (Oncorhynchus mykiss) heart Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 148: S152. DOI: 10.1016/J.Cbpa.2007.06.387  0.322
2007 Shiels H, Thompson S, Block B. 35.1. The effect of temperature on cellular Ca2+ flux in ventricular myocytes from bluefin tuna Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 148: S149. DOI: 10.1016/J.Cbpa.2007.06.377  0.625
2007 Shiels H, Crawford F, Esward M, Dibb K, Loudon A, Trafford A. 1.5. Cardiac survival during temperature change from fish to mammals: a role for altered calcium homeostasis Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 148: S5. DOI: 10.1016/J.Cbpa.2007.06.012  0.396
2007 Galli G, Shiels H, Gilly W, Block B. 1.3. Thermal acclimation confers no tolerance to acute temperature change in cardiac myocytes from the bluefin tuna Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 148: S4-S5. DOI: 10.1016/J.Cbpa.2007.06.010  0.747
2007 Trafford A, Crawford F, Esward M, Dibb K, Shiels H, Loudon A. Cardiac adaptations in preparation for torpor in the Siberian hamster (Phodopus sungorus): A role for altered calcium homeostasis Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 146: S167. DOI: 10.1016/J.Cbpa.2007.01.349  0.339
2007 Galli G, Musyl M, Brill R, Shiels H. Cardiac temperature sensitivity influences depth distribution in pelagic fish species Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 146: S166-S167. DOI: 10.1016/J.Cbpa.2007.01.347  0.701
2006 Galli GL, Taylor EW, Shiels HA. Calcium flux in turtle ventricular myocytes. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R1781-9. PMID 16887918 DOI: 10.1152/ajpregu.00421.2006  0.667
2006 Birkedal R, Shiels HA, Vendelin M. Three-dimensional mitochondrial arrangement in ventricular myocytes: from chaos to order. American Journal of Physiology. Cell Physiology. 291: C1148-58. PMID 16822946 DOI: 10.1152/ajpcell.00236.2006  0.677
2006 Shiels HA, Calaghan SC, White E. The cellular basis for enhanced volume-modulated cardiac output in fish hearts. The Journal of General Physiology. 128: 37-44. PMID 16769795 DOI: 10.1085/jgp.200609543  0.398
2006 Galli GL, Gesser H, Taylor EW, Shiels HA, Wang T. The role of the sarcoplasmic reticulum in the generation of high heart rates and blood pressures in reptiles. The Journal of Experimental Biology. 209: 1956-63. PMID 16651560 DOI: 10.1242/jeb.02228  0.69
2004 Shiels HA, Blank JM, Farrell AP, Block BA. Electrophysiological properties of the L-type Ca(2+) current in cardiomyocytes from bluefin tuna and Pacific mackerel. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R659-68. PMID 14656768 DOI: 10.1152/Ajpregu.00521.2003  0.677
2003 Shiels HA, Vornanen M, Farrell AP. Acute temperature change modulates the response of ICa to adrenergic stimulation in fish cardiomyocytes. Physiological and Biochemical Zoology : Pbz. 76: 816-24. PMID 14988796 DOI: 10.1086/378918  0.563
2002 Shiels HA, Vornanen M, Farrell AP. Effects of temperature on intracellular Ca2+ in trout atrial myocytes. The Journal of Experimental Biology. 205: 3641-50. PMID 12409490  0.551
2002 Shiels HA, Vornanen M, Farrell AP. Temperature dependence of cardiac sarcoplasmic reticulum function in rainbow trout myocytes. The Journal of Experimental Biology. 205: 3631-9. PMID 12409489  0.537
2002 Vornanen M, Shiels HA, Farrell AP. Plasticity of excitation-contraction coupling in fish cardiac myocytes. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 132: 827-46. PMID 12095866  0.602
2002 Shiels HA, Vornanen M, Farrell AP. The force-frequency relationship in fish hearts--a review. Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 132: 811-26. PMID 12095865  0.486
2000 Olsson HI, Yee N, Shiels HA, Brauner C, Farrell AP. A comparison of myocardial beta-adrenoreceptor density and ligand binding affinity among selected teleost fishes. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 170: 545-50. PMID 11128445 DOI: 10.1007/s003600000133  0.416
2000 Shiels HA, Vornanen M, Farrell AP. Temperature-dependence of L-type Ca(2+) channel current in atrial myocytes from rainbow trout. The Journal of Experimental Biology. 203: 2771-80. PMID 10952877  0.567
2000 Shiels HA, Farrell AP. The effect of ryanodine on isometric tension development in isolated ventricular trabeculae from Pacific mackerel (Scomber japonicus). Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 125: 331-41. PMID 10794962  0.54
1999 Shiels HA, Freund EV, Farrell AP, Block BA. The sarcoplasmic reticulum plays a major role in isometric contraction in atrial muscle of yellowfin tuna The Journal of Experimental Biology. 202: 881-90. PMID 10069977  0.647
1998 Shiels HA, Stevens ED, Farrell AP. Effects of temperature, adrenaline and ryanodine on power production in rainbow trout oncorhynchus mykiss ventricular trabeculae The Journal of Experimental Biology. 201: 2701-10. PMID 9732325  0.57
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