Annet Kirabo, Ph.D. - Publications

Affiliations: 
2011 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Physiology Biology, Pharmacology, Oncology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ruggeri Barbaro N, Van Beusecum J, Xiao L, do Carmo L, Pitzer A, Loperena R, Foss JD, Elijovich F, Laffer CL, Montaniel KR, Galindo CL, Chen W, Ao M, Mernaugh RL, Alsouqi A, ... ... Kirabo A, et al. Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation. Cardiovascular Research. PMID 33038226 DOI: 10.1093/Cvr/Cvaa207  0.364
2020 Elijovich F, Laffer CL, Sahinoz M, Pitzer A, Ferguson JF, Kirabo A. The Gut Microbiome, Inflammation, and Salt-Sensitive Hypertension. Current Hypertension Reports. 22: 79. PMID 32880753 DOI: 10.1007/S11906-020-01091-9  0.304
2020 Sahinoz M, Elijovich F, Laffer CL, Pitzer A, Stewart TG, Ikizler TA, Kirabo A. Abstract P139: The Relationship Between Tissue Sodium Storage, Immune Cell Activation And Salt-sensitive Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P139  0.318
2020 Aden LA, Pitzer A, Grimes S, Ray EC, Kleyman TR, Kirabo A. Abstract P131: Jak2 Expression In Cd11c+ Myeloid Cells Plays A Role In Salt-sensitive Hypertension Through An Enac-dependent Mechanism. Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P131  0.402
2020 Patrick DM, de la Visitacion N, Ormseth MJ, Stein C, Davies SS, Yermalitsky VN, Crofford LJ, Williams JM, Dikalov SI, Xiao L, Van Beusecum JP, Fogo A, Kirabo A, Harrison DG. Abstract MP41: A Role Of Isolevuglandins In Systemic Lupus Erythematosus Associated Autoimmunity And Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp41  0.306
2020 Pitzer AL, Barbaro NR, Aden L, Ray EC, Kleyman TR, Kirabo A. Abstract MP38: High Salt Activates The NLRP3 Inflammasome In Antigen Presenting Cells Via ENaC To Promote Salt-Sensitive Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp38  0.374
2020 Pitzer AL, Barbaro NR, Aden L, Ray E, Kleyman T, Kirabo A. High salt activates NLRP3 inflammasome in antigen presenting cells via ENaC to promote salt‐sensitive hypertension The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05532  0.343
2020 Aden LA, Pitzer AA, Grimes S, Ray E, Kleyman T, Kirabo A. Dendritic Cell Specific Jak2 Expression plays a role in in Salt‐Sensitive Hypertension through an ENaC‐dependent Mechanism The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03493  0.366
2019 Pitzer AL, Kirabo A. Dendritic Cell A20: Targeting Hypertension in Autoimmunity. Circulation Research. 125: 1067-1069. PMID 31804913 DOI: 10.1161/Circresaha.119.316198  0.325
2019 Van Beusecum JP, Barbaro NR, McDowell Z, Aden LA, Xiao L, Pandey AK, Itani HA, Himmel LE, Harrison DG, Kirabo A. High Salt Activates CD11c Antigen-Presenting Cells via SGK (Serum Glucocorticoid Kinase) 1 to Promote Renal Inflammation and Salt-Sensitive Hypertension. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31280647 DOI: 10.1161/Hypertensionaha.119.12761  0.444
2019 Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simmons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, ... ... Kirabo A, et al. High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension. Jci Insight. 5. PMID 31162138 DOI: 10.1172/Jci.Insight.126241  0.394
2019 Van Beusecum JP, Xiao L, Barbaro NR, Patrick DM, Kirabo A. Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells. Journal of Visualized Experiments : Jove. PMID 30907877 DOI: 10.3791/59124  0.369
2018 Xiao L, Patrick DM, Aden LA, Kirabo A. Mechanisms of Isolevuglandin-protein Adduct Formation in Inflammation and Hypertension. Prostaglandins & Other Lipid Mediators. PMID 30278231 DOI: 10.1016/J.Prostaglandins.2018.09.008  0.315
2018 Chen W, Patrick DM, Barbaro NR, Bernstein KE, Bernstein KE, Roeth D, Kalkum M, Xiao L, Kirabo A, Harrison DG. Abstract P281: Artificial Dendritic Cells Identify a Major Histocompatibility Complex Class 1 Subset that Activates T Cells in Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P281  0.338
2018 Beusecum JPV, Barbaro NR, Xiao L, Pandey AK, Harrison DG, Kirabo A. Abstract P214: Serum Glucocorticoid Kinase 1 and Sympathetic Nerve Activity in Salt-Sensitive Hypertension. Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P214  0.309
2018 Patrick DM, Xiao L, Chen CW, Ao M, Kirabo A, Harrison DG. Abstract 022: Proteasome Inhibition Prevents Renal Inflammation and Hypertension by Abrogation of Dendritic Cell Autoantigen Presentation Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.022  0.359
2017 Barbaro NR, Foss JD, Kryshtal DO, Tsyba N, Kumaresan S, Xiao L, Mernaugh RL, Itani HA, Loperena R, Chen W, Dikalov S, Titze JM, Knollmann BC, Harrison DG, Kirabo A. Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension. Cell Reports. 21: 1009-1020. PMID 29069584 DOI: 10.1016/J.Celrep.2017.10.002  0.373
2017 Kirabo A. A New Paradigm of Sodium Regulation in Inflammation and Hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00250.2017. PMID 28931546 DOI: 10.1152/Ajpregu.00250.2017  0.339
2017 Barbaro NR, Kirabo A, Harrison DG. A New Role of Mister (MR) T in Hypertension: Mineralocorticoid Receptor, Immune System, and Hypertension. Circulation Research. 120: 1527-1529. PMID 28495982 DOI: 10.1161/Circresaha.117.310985  0.401
2017 Kirabo A, Ryzhov S, Gupte M, Sengsayadeth S, Gumina RJ, Sawyer DB, Galindo CL. Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts. Journal of Molecular and Cellular Cardiology. PMID 28263756 DOI: 10.1016/J.Yjmcc.2017.03.001  0.316
2016 Dixon KB, Davies SS, Kirabo A. Dendritic Cells and Isolevuglandins in Immunity, Inflammation and Hypertension. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00603.2016. PMID 27986660 DOI: 10.1152/Ajpheart.00603.2016  0.372
2016 Foss JD, Kirabo A, Harrison DG. Do High Salt Microenvironments Drive Hypertensive Inflammation? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00414.2016. PMID 27903514 DOI: 10.1152/Ajpregu.00414.2016  0.338
2016 Itani HA, Xiao L, Saleh MA, Wu J, Pilkinton MA, Dale BL, Barbaro NR, Foss JD, Kirabo A, Montaniel KR, Norlander AE, Chen W, Sato R, Navar LG, Mallal SA, et al. CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circulation Research. PMID 26988069 DOI: 10.1161/Circresaha.115.308111  0.321
2015 Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, et al. Immune activation caused by vascular oxidation promotes fibrosis and hypertension. The Journal of Clinical Investigation. PMID 26595812 DOI: 10.1172/Jci80761  0.372
2015 Xiao L, Kirabo A, Wu J, Saleh MA, Zhu L, Wang F, Takahashi T, Loperena R, Foss JD, Mernaugh RL, Chen W, Roberts J, Osborn JW, Itani HA, Harrison DG. Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension. Circulation Research. PMID 26156232 DOI: 10.1161/Circresaha.115.306010  0.344
2015 McMaster WG, Kirabo A, Madhur MS, Harrison DG. Inflammation, immunity, and hypertensive end-organ damage. Circulation Research. 116: 1022-33. PMID 25767287 DOI: 10.1161/Circresaha.116.303697  0.372
2015 Saleh MA, McMaster WG, Wu J, Norlander AE, Funt SA, Thabet SR, Kirabo A, Xiao L, Chen W, Itani HA, Michell D, Huan T, Zhang Y, Takaki S, Titze J, et al. Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. The Journal of Clinical Investigation. 125: 1189-202. PMID 25664851 DOI: 10.1172/Jci76327  0.398
2015 Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA. Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice. Hypertension. 65: 569-76. PMID 25601932 DOI: 10.1161/Hypertensionaha.114.04975  0.344
2014 Trott DW, Thabet SR, Kirabo A, Saleh MA, Itani H, Norlander AE, Wu J, Goldstein A, Arendshorst WJ, Madhur MS, Chen W, Li CI, Shyr Y, Harrison DG. Oligoclonal CD8+ T cells play a critical role in the development of hypertension. Hypertension. 64: 1108-15. PMID 25259750 DOI: 10.1161/Hypertensionaha.114.04147  0.337
2014 Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, et al. DC isoketal-modified proteins activate T cells and promote hypertension. The Journal of Clinical Investigation. 124: 4642-56. PMID 25244096 DOI: 10.1172/Jci74084  0.357
2014 Jin X, Zhao W, Kirabo A, Park SO, Ho WT, Sayeski PP, Zhao ZJ. Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 477-84. PMID 24920845 DOI: 10.4049/Jimmunol.1301946  0.676
2014 Wu J, Thabet SR, Kirabo A, Trott DW, Saleh MA, Xiao L, Madhur MS, Chen W, Harrison DG. Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase. Circulation Research. 114: 616-25. PMID 24347665 DOI: 10.1161/Circresaha.114.302157  0.331
2012 Kirabo A, Park SO, Wamsley HL, Gali M, Baskin R, Reinhard MK, Zhao ZJ, Bisht KS, Keserű GM, Cogle CR, Sayeski PP. The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis. The American Journal of Pathology. 181: 858-65. PMID 22796437 DOI: 10.1016/J.Ajpath.2012.05.033  0.698
2012 Majumder A, Magis AT, Park SO, Figueroa NC, Baskin R, Kirabo A, Allan RW, Zhao ZJ, Bisht KS, Keseru GM, Sayeski PP. A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth. Experimental Hematology. 40: 22-34. PMID 22019628 DOI: 10.1016/J.Exphem.2011.10.003  0.768
2012 Jin X, Zhao W, Kirabo A, Park S, Ho W, Sayeski PP, Zhao ZJ. Aberrant Functions of Mast Cells Are Involved in Pruritus Associated with Polycythemia Vera Blood. 120: 1756-1756. DOI: 10.1182/Blood.V120.21.1756.1756  0.704
2011 Kirabo A, Park SO, Majumder A, Gali M, Reinhard MK, Wamsley HL, Zhao ZJ, Cogle CR, Bisht KS, Keserü GM, Sayeski PP. The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow. Neoplasia (New York, N.Y.). 13: 1058-68. PMID 22131881 DOI: 10.1593/Neo.111112  0.784
2011 Majumder A, Kirabo A, Karrupiah K, Tsuda S, Caldwell-Busby J, Cardounel AJ, Keseru GM, Sayeski PP. Cell death induced by the Jak2 inhibitor, G6, correlates with cleavage of vimentin filaments. Biochemistry. 50: 7774-86. PMID 21823612 DOI: 10.1021/Bi200847N  0.792
2011 Kirabo A, Oh SP, Kasahara H, Wagner KU, Sayeski PP. Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice. Journal of Molecular and Cellular Cardiology. 50: 1026-34. PMID 21420414 DOI: 10.1016/J.Yjmcc.2011.03.005  0.639
2011 Kirabo A, Kearns PN, Jarajapu YP, Sasser JM, Oh SP, Grant MB, Kasahara H, Cardounel AJ, Baylis C, Wagner KU, Sayeski PP. Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species. Cardiovascular Research. 91: 171-9. PMID 21354995 DOI: 10.1093/Cvr/Cvr059  0.619
2011 Kirabo A, Embury J, Kiss R, Polgár T, Gali M, Majumder A, Bisht KS, Cogle CR, Keseru GM, Sayeski PP. The stilbenoid tyrosine kinase inhibitor, G6, suppresses Jak2-V617F-mediated human pathological cell growth in vitro and in vivo. The Journal of Biological Chemistry. 286: 4280-91. PMID 21127060 DOI: 10.1074/Jbc.M110.200774  0.795
2011 Sayeski PP, Kirabo A, Park S, Gali M, Reinhard M, Wamsley HL, Zhao ZJ, Bisht KS, Cogle CR, Keseru GM. The Jak2 Kinase Inhibitor, G6, Reduces the Mutant Burden and Reverses Marrow Fibrosis in a Mouse Model of Jak2-V617F Mediated PMF, Blood. 118: 3858-3858. DOI: 10.1182/Blood.V118.21.3858.3858  0.707
2011 Majumder A, Kirabo A, Karrupiah K, Tsuda S, Caldwell-Busby J, Cardounel AJ, Sayeski PP. Abstract 5127: G6-mediated inhibition of Jak2 tyrosine kinase correlates with the cleavage and cellular reorganization of vimentin Cancer Research. 71: 5127-5127. DOI: 10.1158/1538-7445.Am2011-5127  0.795
2010 Kirabo A, Sayeski PP. Jak2 tyrosine kinase: A potential therapeutic target for AT1 receptor mediated cardiovascular disease Pharmaceuticals. 3: 3478-3493. DOI: 10.3390/Ph3113478  0.645
2009 Kiss R, Polgár T, Kirabo A, Sayyah J, Figueroa NC, List AF, Sokol L, Zuckerman KS, Gali M, Bisht KS, Sayeski PP, Keseru GM. Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening. Bioorganic & Medicinal Chemistry Letters. 19: 3598-601. PMID 19447617 DOI: 10.1016/J.Bmcl.2009.04.138  0.736
2008 McDoom I, Ma X, Kirabo A, Lee KY, Ostrov DA, Sayeski PP. Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation. Biochemistry. 47: 8326-34. PMID 18636744 DOI: 10.1021/Bi800867D  0.643
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