Year |
Citation |
Score |
2020 |
Ruggeri Barbaro N, Van Beusecum J, Xiao L, do Carmo L, Pitzer A, Loperena R, Foss JD, Elijovich F, Laffer CL, Montaniel KR, Galindo CL, Chen W, Ao M, Mernaugh RL, Alsouqi A, ... ... Kirabo A, et al. Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation. Cardiovascular Research. PMID 33038226 DOI: 10.1093/Cvr/Cvaa207 |
0.364 |
|
2020 |
Elijovich F, Laffer CL, Sahinoz M, Pitzer A, Ferguson JF, Kirabo A. The Gut Microbiome, Inflammation, and Salt-Sensitive Hypertension. Current Hypertension Reports. 22: 79. PMID 32880753 DOI: 10.1007/S11906-020-01091-9 |
0.304 |
|
2020 |
Sahinoz M, Elijovich F, Laffer CL, Pitzer A, Stewart TG, Ikizler TA, Kirabo A. Abstract P139: The Relationship Between Tissue Sodium Storage, Immune Cell Activation And Salt-sensitive Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P139 |
0.318 |
|
2020 |
Aden LA, Pitzer A, Grimes S, Ray EC, Kleyman TR, Kirabo A. Abstract P131: Jak2 Expression In Cd11c+ Myeloid Cells Plays A Role In Salt-sensitive Hypertension Through An Enac-dependent Mechanism. Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P131 |
0.402 |
|
2020 |
Patrick DM, de la Visitacion N, Ormseth MJ, Stein C, Davies SS, Yermalitsky VN, Crofford LJ, Williams JM, Dikalov SI, Xiao L, Van Beusecum JP, Fogo A, Kirabo A, Harrison DG. Abstract MP41: A Role Of Isolevuglandins In Systemic Lupus Erythematosus Associated Autoimmunity And Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp41 |
0.306 |
|
2020 |
Pitzer AL, Barbaro NR, Aden L, Ray EC, Kleyman TR, Kirabo A. Abstract MP38: High Salt Activates The NLRP3 Inflammasome In Antigen Presenting Cells Via ENaC To Promote Salt-Sensitive Hypertension Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp38 |
0.374 |
|
2020 |
Pitzer AL, Barbaro NR, Aden L, Ray E, Kleyman T, Kirabo A. High salt activates NLRP3 inflammasome in antigen presenting cells via ENaC to promote salt‐sensitive hypertension The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05532 |
0.343 |
|
2020 |
Aden LA, Pitzer AA, Grimes S, Ray E, Kleyman T, Kirabo A. Dendritic Cell Specific Jak2 Expression plays a role in in Salt‐Sensitive Hypertension through an ENaC‐dependent Mechanism The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03493 |
0.366 |
|
2019 |
Pitzer AL, Kirabo A. Dendritic Cell A20: Targeting Hypertension in Autoimmunity. Circulation Research. 125: 1067-1069. PMID 31804913 DOI: 10.1161/Circresaha.119.316198 |
0.325 |
|
2019 |
Van Beusecum JP, Barbaro NR, McDowell Z, Aden LA, Xiao L, Pandey AK, Itani HA, Himmel LE, Harrison DG, Kirabo A. High Salt Activates CD11c Antigen-Presenting Cells via SGK (Serum Glucocorticoid Kinase) 1 to Promote Renal Inflammation and Salt-Sensitive Hypertension. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31280647 DOI: 10.1161/Hypertensionaha.119.12761 |
0.444 |
|
2019 |
Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simmons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, ... ... Kirabo A, et al. High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension. Jci Insight. 5. PMID 31162138 DOI: 10.1172/Jci.Insight.126241 |
0.394 |
|
2019 |
Van Beusecum JP, Xiao L, Barbaro NR, Patrick DM, Kirabo A. Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells. Journal of Visualized Experiments : Jove. PMID 30907877 DOI: 10.3791/59124 |
0.369 |
|
2018 |
Xiao L, Patrick DM, Aden LA, Kirabo A. Mechanisms of Isolevuglandin-protein Adduct Formation in Inflammation and Hypertension. Prostaglandins & Other Lipid Mediators. PMID 30278231 DOI: 10.1016/J.Prostaglandins.2018.09.008 |
0.315 |
|
2018 |
Chen W, Patrick DM, Barbaro NR, Bernstein KE, Bernstein KE, Roeth D, Kalkum M, Xiao L, Kirabo A, Harrison DG. Abstract P281: Artificial Dendritic Cells Identify a Major Histocompatibility Complex Class 1 Subset that Activates T Cells in Hypertension Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P281 |
0.338 |
|
2018 |
Beusecum JPV, Barbaro NR, Xiao L, Pandey AK, Harrison DG, Kirabo A. Abstract P214: Serum Glucocorticoid Kinase 1 and Sympathetic Nerve Activity in Salt-Sensitive Hypertension. Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P214 |
0.309 |
|
2018 |
Patrick DM, Xiao L, Chen CW, Ao M, Kirabo A, Harrison DG. Abstract 022: Proteasome Inhibition Prevents Renal Inflammation and Hypertension by Abrogation of Dendritic Cell Autoantigen Presentation Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.022 |
0.359 |
|
2017 |
Barbaro NR, Foss JD, Kryshtal DO, Tsyba N, Kumaresan S, Xiao L, Mernaugh RL, Itani HA, Loperena R, Chen W, Dikalov S, Titze JM, Knollmann BC, Harrison DG, Kirabo A. Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension. Cell Reports. 21: 1009-1020. PMID 29069584 DOI: 10.1016/J.Celrep.2017.10.002 |
0.373 |
|
2017 |
Kirabo A. A New Paradigm of Sodium Regulation in Inflammation and Hypertension. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00250.2017. PMID 28931546 DOI: 10.1152/Ajpregu.00250.2017 |
0.339 |
|
2017 |
Barbaro NR, Kirabo A, Harrison DG. A New Role of Mister (MR) T in Hypertension: Mineralocorticoid Receptor, Immune System, and Hypertension. Circulation Research. 120: 1527-1529. PMID 28495982 DOI: 10.1161/Circresaha.117.310985 |
0.401 |
|
2017 |
Kirabo A, Ryzhov S, Gupte M, Sengsayadeth S, Gumina RJ, Sawyer DB, Galindo CL. Neuregulin-1β induces proliferation, survival and paracrine signaling in normal human cardiac ventricular fibroblasts. Journal of Molecular and Cellular Cardiology. PMID 28263756 DOI: 10.1016/J.Yjmcc.2017.03.001 |
0.316 |
|
2016 |
Dixon KB, Davies SS, Kirabo A. Dendritic Cells and Isolevuglandins in Immunity, Inflammation and Hypertension. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00603.2016. PMID 27986660 DOI: 10.1152/Ajpheart.00603.2016 |
0.372 |
|
2016 |
Foss JD, Kirabo A, Harrison DG. Do High Salt Microenvironments Drive Hypertensive Inflammation? American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00414.2016. PMID 27903514 DOI: 10.1152/Ajpregu.00414.2016 |
0.338 |
|
2016 |
Itani HA, Xiao L, Saleh MA, Wu J, Pilkinton MA, Dale BL, Barbaro NR, Foss JD, Kirabo A, Montaniel KR, Norlander AE, Chen W, Sato R, Navar LG, Mallal SA, et al. CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circulation Research. PMID 26988069 DOI: 10.1161/Circresaha.115.308111 |
0.321 |
|
2015 |
Wu J, Saleh MA, Kirabo A, Itani HA, Montaniel KR, Xiao L, Chen W, Mernaugh RL, Cai H, Bernstein KE, Goronzy JJ, Weyand CM, Curci JA, Barbaro NR, Moreno H, et al. Immune activation caused by vascular oxidation promotes fibrosis and hypertension. The Journal of Clinical Investigation. PMID 26595812 DOI: 10.1172/Jci80761 |
0.372 |
|
2015 |
Xiao L, Kirabo A, Wu J, Saleh MA, Zhu L, Wang F, Takahashi T, Loperena R, Foss JD, Mernaugh RL, Chen W, Roberts J, Osborn JW, Itani HA, Harrison DG. Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension. Circulation Research. PMID 26156232 DOI: 10.1161/Circresaha.115.306010 |
0.344 |
|
2015 |
McMaster WG, Kirabo A, Madhur MS, Harrison DG. Inflammation, immunity, and hypertensive end-organ damage. Circulation Research. 116: 1022-33. PMID 25767287 DOI: 10.1161/Circresaha.116.303697 |
0.372 |
|
2015 |
Saleh MA, McMaster WG, Wu J, Norlander AE, Funt SA, Thabet SR, Kirabo A, Xiao L, Chen W, Itani HA, Michell D, Huan T, Zhang Y, Takaki S, Titze J, et al. Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. The Journal of Clinical Investigation. 125: 1189-202. PMID 25664851 DOI: 10.1172/Jci76327 |
0.398 |
|
2015 |
Kamat NV, Thabet SR, Xiao L, Saleh MA, Kirabo A, Madhur MS, Delpire E, Harrison DG, McDonough AA. Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice. Hypertension. 65: 569-76. PMID 25601932 DOI: 10.1161/Hypertensionaha.114.04975 |
0.344 |
|
2014 |
Trott DW, Thabet SR, Kirabo A, Saleh MA, Itani H, Norlander AE, Wu J, Goldstein A, Arendshorst WJ, Madhur MS, Chen W, Li CI, Shyr Y, Harrison DG. Oligoclonal CD8+ T cells play a critical role in the development of hypertension. Hypertension. 64: 1108-15. PMID 25259750 DOI: 10.1161/Hypertensionaha.114.04147 |
0.337 |
|
2014 |
Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, et al. DC isoketal-modified proteins activate T cells and promote hypertension. The Journal of Clinical Investigation. 124: 4642-56. PMID 25244096 DOI: 10.1172/Jci74084 |
0.357 |
|
2014 |
Jin X, Zhao W, Kirabo A, Park SO, Ho WT, Sayeski PP, Zhao ZJ. Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 477-84. PMID 24920845 DOI: 10.4049/Jimmunol.1301946 |
0.676 |
|
2014 |
Wu J, Thabet SR, Kirabo A, Trott DW, Saleh MA, Xiao L, Madhur MS, Chen W, Harrison DG. Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase. Circulation Research. 114: 616-25. PMID 24347665 DOI: 10.1161/Circresaha.114.302157 |
0.331 |
|
2012 |
Kirabo A, Park SO, Wamsley HL, Gali M, Baskin R, Reinhard MK, Zhao ZJ, Bisht KS, Keserű GM, Cogle CR, Sayeski PP. The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis. The American Journal of Pathology. 181: 858-65. PMID 22796437 DOI: 10.1016/J.Ajpath.2012.05.033 |
0.698 |
|
2012 |
Majumder A, Magis AT, Park SO, Figueroa NC, Baskin R, Kirabo A, Allan RW, Zhao ZJ, Bisht KS, Keseru GM, Sayeski PP. A46, a benzothiophene-derived compound, suppresses Jak2-mediated pathologic cell growth. Experimental Hematology. 40: 22-34. PMID 22019628 DOI: 10.1016/J.Exphem.2011.10.003 |
0.768 |
|
2012 |
Jin X, Zhao W, Kirabo A, Park S, Ho W, Sayeski PP, Zhao ZJ. Aberrant Functions of Mast Cells Are Involved in Pruritus Associated with Polycythemia Vera Blood. 120: 1756-1756. DOI: 10.1182/Blood.V120.21.1756.1756 |
0.704 |
|
2011 |
Kirabo A, Park SO, Majumder A, Gali M, Reinhard MK, Wamsley HL, Zhao ZJ, Cogle CR, Bisht KS, Keserü GM, Sayeski PP. The Jak2 inhibitor, G6, alleviates Jak2-V617F-mediated myeloproliferative neoplasia by providing significant therapeutic efficacy to the bone marrow. Neoplasia (New York, N.Y.). 13: 1058-68. PMID 22131881 DOI: 10.1593/Neo.111112 |
0.784 |
|
2011 |
Majumder A, Kirabo A, Karrupiah K, Tsuda S, Caldwell-Busby J, Cardounel AJ, Keseru GM, Sayeski PP. Cell death induced by the Jak2 inhibitor, G6, correlates with cleavage of vimentin filaments. Biochemistry. 50: 7774-86. PMID 21823612 DOI: 10.1021/Bi200847N |
0.792 |
|
2011 |
Kirabo A, Oh SP, Kasahara H, Wagner KU, Sayeski PP. Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice. Journal of Molecular and Cellular Cardiology. 50: 1026-34. PMID 21420414 DOI: 10.1016/J.Yjmcc.2011.03.005 |
0.639 |
|
2011 |
Kirabo A, Kearns PN, Jarajapu YP, Sasser JM, Oh SP, Grant MB, Kasahara H, Cardounel AJ, Baylis C, Wagner KU, Sayeski PP. Vascular smooth muscle Jak2 mediates angiotensin II-induced hypertension via increased levels of reactive oxygen species. Cardiovascular Research. 91: 171-9. PMID 21354995 DOI: 10.1093/Cvr/Cvr059 |
0.619 |
|
2011 |
Kirabo A, Embury J, Kiss R, Polgár T, Gali M, Majumder A, Bisht KS, Cogle CR, Keseru GM, Sayeski PP. The stilbenoid tyrosine kinase inhibitor, G6, suppresses Jak2-V617F-mediated human pathological cell growth in vitro and in vivo. The Journal of Biological Chemistry. 286: 4280-91. PMID 21127060 DOI: 10.1074/Jbc.M110.200774 |
0.795 |
|
2011 |
Sayeski PP, Kirabo A, Park S, Gali M, Reinhard M, Wamsley HL, Zhao ZJ, Bisht KS, Cogle CR, Keseru GM. The Jak2 Kinase Inhibitor, G6, Reduces the Mutant Burden and Reverses Marrow Fibrosis in a Mouse Model of Jak2-V617F Mediated PMF, Blood. 118: 3858-3858. DOI: 10.1182/Blood.V118.21.3858.3858 |
0.707 |
|
2011 |
Majumder A, Kirabo A, Karrupiah K, Tsuda S, Caldwell-Busby J, Cardounel AJ, Sayeski PP. Abstract 5127: G6-mediated inhibition of Jak2 tyrosine kinase correlates with the cleavage and cellular reorganization of vimentin Cancer Research. 71: 5127-5127. DOI: 10.1158/1538-7445.Am2011-5127 |
0.795 |
|
2010 |
Kirabo A, Sayeski PP. Jak2 tyrosine kinase: A potential therapeutic target for AT1 receptor mediated cardiovascular disease Pharmaceuticals. 3: 3478-3493. DOI: 10.3390/Ph3113478 |
0.645 |
|
2009 |
Kiss R, Polgár T, Kirabo A, Sayyah J, Figueroa NC, List AF, Sokol L, Zuckerman KS, Gali M, Bisht KS, Sayeski PP, Keseru GM. Identification of a novel inhibitor of JAK2 tyrosine kinase by structure-based virtual screening. Bioorganic & Medicinal Chemistry Letters. 19: 3598-601. PMID 19447617 DOI: 10.1016/J.Bmcl.2009.04.138 |
0.736 |
|
2008 |
McDoom I, Ma X, Kirabo A, Lee KY, Ostrov DA, Sayeski PP. Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation. Biochemistry. 47: 8326-34. PMID 18636744 DOI: 10.1021/Bi800867D |
0.643 |
|
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