| Year |
Citation |
Score |
| 2006 |
Gan Y, Spencer TA. Cholesterol surrogates incorporating a benzophenone as part of the sterol tetracycle. The Journal of Organic Chemistry. 71: 5870-5. PMID 16872165 DOI: 10.1021/Jo060480Y |
0.339 |
|
| 2006 |
Gan Y, Blank DH, Ney JE, Spencer TA. Nonsteroidal benzophenone-containing analogues of cholesterol. The Journal of Organic Chemistry. 71: 5864-9. PMID 16872164 DOI: 10.1021/Jo060481Q |
0.317 |
|
| 2005 |
Wang P, Spencer TA. Preparation of isotopically labelled benzophenone-containing lipid analogues Journal of Labelled Compounds and Radiopharmaceuticals. 48: 781-788. DOI: 10.1002/Jlcr.996 |
0.307 |
|
| 2004 |
Nakamura Y, Kotite L, Gan Y, Spencer TA, Fielding CJ, Fielding PE. Molecular mechanism of reverse cholesterol transport: reaction of pre-beta-migrating high-density lipoprotein with plasma lecithin/cholesterol acyltransferase. Biochemistry. 43: 14811-20. PMID 15544352 DOI: 10.1021/Bi0485629 |
0.301 |
|
| 2004 |
Spencer TA, Wang P, Li D, Russel JS, Blank DH, Huuskonen J, Fielding PE, Fielding CJ. Benzophenone-containing cholesterol surrogates: synthesis and biological evaluation. Journal of Lipid Research. 45: 1510-8. PMID 15175357 DOI: 10.1194/Jlr.M400081-Jlr200 |
0.714 |
|
| 2004 |
Wang P, Blank DH, Spencer TA. Synthesis of benzophenone-containing analogues of phosphatidylcholine. The Journal of Organic Chemistry. 69: 2693-702. PMID 15074915 DOI: 10.1021/Jo030329D |
0.32 |
|
| 2003 |
Zhang Y, Yu C, Liu J, Spencer TA, Chang CC, Chang TY. Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1. The Journal of Biological Chemistry. 278: 11642-7. PMID 12533546 DOI: 10.1074/Jbc.M211559200 |
0.313 |
|
| 2001 |
Spencer TA, Li D, Russel JS, Collins JL, Bledsoe RK, Consler TG, Moore LB, Galardi CM, McKee DD, Moore JT, Watson MA, Parks DJ, Lambert MH, Willson TM. Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha. Journal of Medicinal Chemistry. 44: 886-97. PMID 11300870 DOI: 10.1021/Jm0004749 |
0.694 |
|
| 2000 |
Li D, Spencer TA. Synthesis of 7alpha-hydroxy derivatives of regulatory oxysterols. Steroids. 65: 529-35. PMID 10978732 DOI: 10.1016/S0039-128X(00)00131-8 |
0.727 |
|
| 2000 |
Spencer TA, Li D, Russel JS, Tomkinson NC, Willson TM. Further studies on the synthesis of 24(S),25-epoxycholesterol. A new, efficient preparation of desmosterol. The Journal of Organic Chemistry. 65: 1919-23. PMID 10774010 DOI: 10.1021/Jo991370C |
0.732 |
|
| 1998 |
Tomkinson NCO, Willson TM, Russel JS, Spencer TA. Efficient, stereoselective synthesis of 24(S),25-epoxycholesterol Journal of Organic Chemistry. 63: 9919-9923. DOI: 10.1021/Jo981753V |
0.348 |
|
| 1997 |
Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS, Winegar DA, Blanchard DE, Spencer TA, Willson TM. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. The Journal of Biological Chemistry. 272: 3137-40. PMID 9013544 DOI: 10.1074/Jbc.272.6.3137 |
0.316 |
|
| 1996 |
Castro A, Erickson SK, Shechter I, Spencer TA. Synthesis and biological evaluation of nonionic prenyl, geranyl, and farnesyl diphosphate surrogates Bioorganic Chemistry. 24: 242-250. DOI: 10.1006/Bioo.1996.0022 |
0.338 |
|
| 1992 |
Ray NC, Raveendranath PC, Spencer TA. A synthesis of (R)-mevalonolactone Tetrahedron. 48: 9427-9432. DOI: 10.1016/S0040-4020(01)88311-3 |
0.317 |
|
| 1991 |
Kaydos JA, Spencer TA. Attempted synthesis of furanocyclobutenes from .gamma.-keto cyclobutanones Journal of Organic Chemistry. 56: 425-428. DOI: 10.1021/Jo00001A079 |
0.313 |
|
| 1990 |
Raveendranath PC, Newcomb LF, Ray NC, Clark DS, Spencer TA. 7,7-Disubstituted Derivatives of 4,4–10β-Trimethyl-trans-Decal-3β-ol(TMD) Synthetic Communications. 20: 2723-2731. DOI: 10.1080/00397919008051481 |
0.336 |
|
| 1989 |
Bushweller JH, Anzalone L, Spencer TA. Synthesis of Cis- And 77Jaws-1-Methylcyclohexane-1,4-Diols and Their 4-Hemisuccinate Esters Synthetic Communications. 19: 745-754. DOI: 10.1080/00397918908050989 |
0.311 |
|
| 1989 |
Ruhl KK, Anzalone L, Arguropoulos ED, Gayen AK, Spencer TA. Azadecalin analogs of 4,4,10β-trimethyl-trans-decal-3β-ol: Synthesis and assay as inhibitors of oxidosqualene cyclase Bioorganic Chemistry. 17: 108-120. DOI: 10.1016/0045-2068(89)90012-6 |
0.311 |
|
| 1988 |
Vite GD, Spencer TA. Exploration of a novel cyclization reaction. Synthesis of (.+-.)-.beta.-eudesmol Journal of Organic Chemistry. 53: 2555-2560. DOI: 10.1021/Jo00246A029 |
0.313 |
|
| 1985 |
Byers JH, Spencer TA. Improved preparation and new reactions of β -(1-phenylthio) cyclopropyl enones Tetrahedron Letters. 26: 717-720. DOI: 10.1016/S0040-4039(00)89117-0 |
0.329 |
|
| 1983 |
Garst ME, Spencer TA. A novel furan synthesis. Menthofuran from 2-bromo-4-methylcyclohexanone and (.alpha.-formylethylidene)triphenylphosphorane Journal of Organic Chemistry. 14: 2442-2443. DOI: 10.1021/Jo00162A037 |
0.351 |
|
| 1980 |
Jacob JN, Nelson JA, Spencer TA. Synthesis of trans-2-decalones with 9.alpha. leaving groups and 8.beta. general bases for 1.beta. proton abstraction Journal of Organic Chemistry. 45: 1645-1650. DOI: 10.1021/Jo01297A022 |
0.318 |
|
| 1980 |
Gula MJ, Spencer TA. Syntheses of 10-(carboxymethyl)-trans-decal-2-one Journal of Organic Chemistry. 45: 805-809. DOI: 10.1021/Jo01293A009 |
0.304 |
|
| 1976 |
Townsend JM, Reingold ID, Kendall MCR, Spencer TA. Dehydrobromination of .alpha.-bromo ketones with palladium tetrakis(triphenylphosphine) Cheminform. 7. DOI: 10.1002/Chin.197601123 |
0.318 |
|
| 1975 |
Czarny MR, Maheshwari KK, Nelson JA, Spencer TA. Synthesis of stereoisomeric 4-hydroxymethyl-4-methyl-3beta-hydroxy-cholestanes, -androstanes, and -10-methyl-trans-decalins. The Journal of Organic Chemistry. 40: 2079-85. PMID 1142043 DOI: 10.1002/Chin.197542444 |
0.335 |
|
| 1975 |
Townsend JM, Reingold ID, Kendall MCR, Spencer TA. Dehydrobromination of .alpha.-bromo ketones with palladium tetrakis(triphenylphosphine) Journal of Organic Chemistry. 40: 2976-2978. DOI: 10.1021/Jo00908A035 |
0.318 |
|
| 1975 |
Nelson JA, Kahn S, Spencer TA, Sharpless KB, Clayton RB. Some aspects of substrate specificity in biological demethylation at C4 of steroids Bioorganic Chemistry. 4: 363-376. DOI: 10.1016/0045-2068(75)90047-4 |
0.56 |
|
| 1974 |
Garst ME, Spencer TA. Furan synthesis of reaction of .alpha.-hydroxy ketones with .beta.-ethoxyvinyltriphenylphosphonium salts Journal of Organic Chemistry. 39: 584-585. DOI: 10.1021/Jo00918A044 |
0.36 |
|
| 1974 |
Garst ME, Spencer TA. Furan Synthesis By Reaction Of Alpha-Hydroxy Ketones With Beta-Ethoxyvinyltriphenylphosphonium Salts Cheminform. 5. DOI: 10.1002/Chin.197420318 |
0.36 |
|
| 1973 |
Garst ME, Spencer TA. General method for the synthesis of 3- and 3,4-substituted furans. Simple syntheses of perillene and dendrolasin Journal of the American Chemical Society. 95: 250-252. DOI: 10.1021/Ja00782A051 |
0.324 |
|
| 1972 |
Spencer TA, Ariel RA, Rouse DS, Dunlap WP. Pyrolysis of 2-acetoxy-2-methylcyclopentane-1,3-dione and 3-acetoxy-3-methylpentane-2,4-dione Journal of Organic Chemistry. 37: 2349-2351. DOI: 10.1021/Jo00979A033 |
0.323 |
|
| 1970 |
Rahman R, Sharpless KB, Spencer TA, Clayton RB. Removal of the 4,4-dimethyl carbons in the enzymic conversion of lanosterol to cholesterol. Initial loss of the 4-alpha-methyl group. The Journal of Biological Chemistry. 245: 2667-71. PMID 5445804 |
0.551 |
|
| 1970 |
Smith RAJ, Spencer TA. Synthesis of 2-alkylidene ketones. Chemistry of boron difluoride complexes of 2-formyl ketones Journal of Organic Chemistry. 35: 3220-3223. DOI: 10.1021/Jo00835A007 |
0.332 |
|
| 1969 |
Sharpless KB, Snyder TE, Spencer TA, Maheshwari KK, Nelson JA. Biological demethylation of 4,4-dimethyl sterols, Evidence for enzymic epimerization of the 4beta-methyl group prior to its oxidative removal. Journal of the American Chemical Society. 91: 3394-6. PMID 5791927 DOI: 10.1021/Ja01040A065 |
0.563 |
|
| 1968 |
Spencer T, Weaver T, Villarica R, Friary R, Posler J, Schwartz M. Correction. Synthesis of Methyl Deisopropyldehydroabietate. Diterpenoid Synthesis by the AB → ABC Approach. Journal of Organic Chemistry. 33: 4315-4315. DOI: 10.1021/Jo01275A620 |
0.345 |
|
| 1968 |
Spencer TA, Weaver TD, Villarica RM, Friary RJ, Posler J, Schwartz MA. Syntheses of methyl deisopropyldehydroabietate. Diterpenoid synthesis by the AB.fwdarw.ABC approach Journal of Organic Chemistry. 33: 712-719. DOI: 10.1021/Jo01266A049 |
0.336 |
|
| 1968 |
Sharpless KB, Snyder TE, Spencer TA, Maheshwari KK, Guhn G, Clayton RB. Biological demethylation of 4,4-dimethyl sterols. Initial removal of the 4.alpha.-methyl group Journal of the American Chemical Society. 90: 6874-6875. DOI: 10.1021/Ja01026A073 |
0.585 |
|
| 1968 |
Spencer TA, Villarica RM, Storm DL, Weaver TD, Friary RJ, Posler J, Shafer PR. Additions and Corrections - Total Synthesis of Racemic Methyl Vinhaticoate. Journal of the American Chemical Society. 90: 541-541. DOI: 10.1021/Ja01004A604 |
0.346 |
|
| 1967 |
Spencer TA, Britton RW, Watt DS. Chemistry of enolates from zinc reduction of .alpha.-bromo ketones. New method of substitution .alpha. to carbonyl groups Journal of the American Chemical Society. 89: 5727-5729. DOI: 10.1021/Ja00998A055 |
0.328 |
|
| 1967 |
Spencer TA, Villarica RM, Storm DL, Weaver TD, Friary RJ, Posler J, Shafer PR. Total synthesis of racemic methyl vinhaticoate Journal of the American Chemical Society. 89: 5497-5499. DOI: 10.1021/Ja00997A060 |
0.346 |
|
| 1967 |
Storm DL, Spencer TA. Furan synthesis by 1,4 addition of carboethoxycarbene to α-methoxymethylene ketones Tetrahedron Letters. 8: 1865-1867. DOI: 10.1016/S0040-4039(00)90743-3 |
0.335 |
|
| 1965 |
Spencer TA, Weaver TD, Greco WJ. Synthesis of Resin Acid Intermediates. 4β,9β-Dimethyl-4α-carboxy-8β-hydroxy-trans-decalin from 4-Carboethoxy-9-methyl-Δ4,10-octalin-3,8-dione Journal of Organic Chemistry. 30: 3333-3336. DOI: 10.1021/Jo01021A017 |
0.319 |
|
| 1965 |
Spencer TA, Schmiegel KK, Schmiegel WW. Synthesis of 1,9-cis-Diacetoxy-5-methyl-Δ5,10-octalone-6. Novel Lithium—Ammonia Reduction of the γ,δ-Diacetoxy α,β-Unsaturated Ketone System1a Journal of Organic Chemistry. 30: 1626-1629. DOI: 10.1021/Jo01016A072 |
0.342 |
|
| 1965 |
Spencer TA, Baldwin SW, Schmiegel KK. Pyrolysis of 2-acetoxy-2-(3-oxobutyl)cyclohexane-1,3-dione Journal of Organic Chemistry. 30: 1294-1296. DOI: 10.1021/Jo01015A537 |
0.3 |
|
| 1964 |
Spencer TA, Newton MD, Baldwin SW. Condensation of diethyl malonate with methyl vinyl ketone Journal of Organic Chemistry. 29: 787-789. DOI: 10.1021/Jo01027A004 |
0.309 |
|
| 1964 |
Spencer TA, Schwartz MA, Sharpless KB. Synthesis of Resin Acid Intermediates. 8α,10β-Dimethyl-8β-carbomethoxy-Δ1,9,3,4-hexahydronaphthalone-2 and 8α,10β-Dimethyl-8β-carbomethoxy-Δ1,9-octalone-2 The Journal of Organic Chemistry. 29: 782-786. DOI: 10.1021/Jo01027A003 |
0.557 |
|
| 1962 |
Spencer TA, Newton MD. The synthesis of isocamphorquinone Tetrahedron Letters. 3: 1019-1021. DOI: 10.1016/S0040-4039(00)70949-X |
0.338 |
|
| 1959 |
Tamelen EEV, Spencer TA, Allen DS, Orvis RL. The Total Synthesis Of Colchicine Journal of the American Chemical Society. 81: 6341-6342. DOI: 10.1021/Ja01532A070 |
0.338 |
|
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