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Ahmed Heikal - Publications

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Biomedical Engineering, Radiology
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45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mersch SA, Bergman S, Sheets ED, Boersma AJ, Heikal AA. Two-photon excited-state dynamics of mEGFP-linker-mScarlet-I crowding biosensor in controlled environments. Physical Chemistry Chemical Physics : Pccp. 26: 3927-3940. PMID 38231116 DOI: 10.1039/d3cp04733d  0.754
2021 Kay TM, Aplin CP, Simonet R, Beenken J, Miller RC, Libal C, Boersma AJ, Sheets ED, Heikal AA. Molecular Brightness Approach for FRET Analysis of Donor-Linker-Acceptor Constructs at the Single Molecule Level: A Concept. Frontiers in Molecular Biosciences. 8: 730394. PMID 34595208 DOI: 10.3389/fmolb.2021.730394  0.745
2021 Aplin CP, Miller RC, Kay TM, Heikal AA, Boersma AJ, Sheets ED. Fluorescence Depolarization Dynamics of Ionic Strength Sensors using Time-Resolved Anisotropy. Biophysical Journal. PMID 33582140 DOI: 10.1016/j.bpj.2021.01.035  0.732
2020 Miller RC, Aplin CP, Kay TM, Leighton R, Libal C, Simonet R, Cembran A, Heikal AA, Boersma AJ, Sheets ED. Correction to "FRET Analysis of Ionic Strength Sensors in the Hofmeister Series of Salt Solutions Using Fluorescence Lifetime Measurements". The Journal of Physical Chemistry. B. PMID 32871075 DOI: 10.1021/Acs.Jpcb.0C07220  0.694
2020 Miller RC, Aplin CP, Kay TM, Leighton R, Libal C, Simonet R, Cembran A, Heikal AA, Boersma AJ, Sheets ED. FRET Analysis of Ionic Strength Sensors in the Hofmeister Series of Salt Solutions Using Fluorescence Lifetime Measurements. The Journal of Physical Chemistry. B. PMID 32267692 DOI: 10.1021/Acs.Jpcb.9B10498  0.709
2020 Beenken JA, Tetteh-Jada E, Aplin CP, Kay TM, Boersma AJ, Heikal AA, Sheets ED. Comparative Photophysical Studies of mCerulean3 and mTurquoise2.1 as FRET Donors Biophysical Journal. 118: 44a. DOI: 10.1016/j.bpj.2019.11.423  0.637
2020 Kay TM, Libal C, Aplin CP, Boersma AJ, Sheets ED, Heikal AA. Single-Molecule Studies of Hetero-FRET Biosensors to Environmental Ionic Strength using Different Modalities of Fluorescence Correlation Spectroscopy Biophysical Journal. 118: 615a. DOI: 10.1016/J.Bpj.2019.11.3322  0.729
2020 Aplin CP, Miller RC, Kay TM, Cembran A, Boersma AJ, Heikal AA, Sheets ED. Investigating Novel Hetero-FRET Biosensors for Environmental Ionic Strength using Experimental and Theoretical Approaches Biophysical Journal. 118: 508a. DOI: 10.1016/J.Bpj.2019.11.2798  0.629
2019 Schwarz J, Leopold HJ, Leighton R, Miller RC, Aplin CP, Arnold BJ, Heikal AA, Sheets ED. Macromolecular Crowding Effects on Energy Transfer Efficiency and Donor-Acceptor Distance of Hetero-FRET Sensors using Time-Resolved Fluorescence. Methods and Applications in Fluorescence. PMID 30690439 DOI: 10.1088/2050-6120/ab0242  0.744
2019 Miller RC, Simonet R, Libal C, Aplin C, Cong A, Gurumani M, Kauffman E, Bok Lee H, Boersma AJ, Sheets ED, Heikal AA. FRET at the Single Molecule Level using Molecular Brightness and Fluorescence Correlation Spectroscopy Biophysical Journal. 116: 567a. DOI: 10.1016/J.Bpj.2018.11.3049  0.717
2019 Miller R, Aplin C, Cong A, Libal C, Simonet R, Kauffman E, Gurumani M, Leighton R, Naughton A, Marshik J, Boersma AJ, Heikal AA, Sheets ED. Measuring Ionic Strength Changes using Fluorescence Lifetime and Time-Resolved Anisotropy Biophysical Journal. 116: 472a. DOI: 10.1016/J.Bpj.2018.11.2551  0.726
2018 Leopold H, Leighton R, Schwarz J, Boersma AJ, Sheets ED, Heikal AA. Crowding Effects on Energy Transfer Efficiencies of hetero-FRET Probes as Measured using Time-Resolved Fluorescence Anisotropy. The Journal of Physical Chemistry. B. PMID 30571116 DOI: 10.1021/acs.jpcb.8b09829  0.756
2018 Lee HB, Cong A, Leopold H, Currie M, Boersma AJ, Sheets ED, Heikal AA. Rotational and translational diffusion of size-dependent fluorescent probes in homogeneous and heterogeneous environments. Physical Chemistry Chemical Physics : Pccp. PMID 30204161 DOI: 10.1039/c8cp03873b  0.757
2018 Bok Lee H, Currie M, Leopold H, Sheets ED, Heikal AA. Single Molecule Fluorescence Fluctuation Analysis of Fluorescent Probes in Crowded Environments: Molecular Size and Shape Dependence Biophysical Journal. 114: 682a. DOI: 10.1016/J.Bpj.2017.11.3681  0.743
2018 Leighton RE, Leopold H, Schwarz J, Boersma AJ, Sheets ED, Heikal AA. Modeling the Rotational Dynamics of Novel Hetero-FRET Probes as Measured using Time-Resolved Anisotropy Biophysical Journal. 114: 341a-342a. DOI: 10.1016/j.bpj.2017.11.1907  0.679
2017 Currie M, Leopold H, Schwarz J, Boersma AJ, Sheets ED, Heikal AA. Fluorescence Dynamics of a FRET Probe Designed for Crowding Studies. The Journal of Physical Chemistry. B. PMID 28520430 DOI: 10.1021/acs.jpcb.7b01306  0.745
2017 Schwarz J, Currie M, Leopold H, Boersma AJ, Heikal AA, Sheets ED. Monitoring Macromolecular Crowding via FRET using Wavelength-Dependent Fluorescence Lifetime Measurements Biophysical Journal. 112: 347a. DOI: 10.1016/j.bpj.2016.11.1885  0.737
2017 Leopold H, Currie M, Schwarz J, Boersma AJ, Sheets ED, Heikal AA. Characterization of a Novel FRET Probe in a Crowded Environment using Time-Resolved Anisotropy Biophysical Journal. 112: 346a. DOI: 10.1016/j.bpj.2016.11.1878  0.697
2016 Currie M, Berry B, Ward T, Sheets ED, Heikal AA. Modeling Macromolecular Crowding through Translational and Rotational Diffusion of Small Molecular Probes Biophysical Journal. 110: 50a. DOI: 10.1016/j.bpj.2015.11.335  0.663
2016 Floden T, Warner R, Heikal AA, Sheets ED. Investigating Membrane Domain Dynamics using Multimodal Optical Microscopy Biophysical Journal. 110: 568a. DOI: 10.1016/J.Bpj.2015.11.3040  0.679
2016 Gardeen S, Johnson JL, Heikal A. Fluorescence Micro-Spectroscopy Assessment of the in Vitro Dimerization of BACE1-GFP Fusion Protein in Cultured Cells Biophysical Journal. 110: 319a. DOI: 10.1016/J.Bpj.2015.11.1712  0.725
2015 Currie M, Thao C, Timerman R, Welty R, Berry B, Sheets ED, Heikal AA. Multiscale diffusion of a molecular probe in a crowded environment: A concept Proceedings of Spie - the International Society For Optical Engineering. 9584. DOI: 10.1117/12.2188746  0.728
2015 Warner R, Floden T, Heikal AA, Sheets ED. Molecular and Mechanical Manipulation of Membrane Domains in Planar Supported Bilayers Biophysical Journal. 108: 87a. DOI: 10.1016/j.bpj.2014.11.506  0.613
2014 Heikal A. Natural bioluminescence in living cells for biomedical diagnostics Spie Newsroom. DOI: 10.1117/2.1201410.005615  0.319
2014 Sheets ED, Welty R, Heikal AA. Macromolecular Crowding Effects on the Multiscale Diffusion of Single Molecules Biophysical Journal. 106: 736a. DOI: 10.1016/J.Bpj.2013.11.4057  0.708
2014 Thao C, Timerman R, Welty R, Wickramasinghe D, Heikal A. What Kind of Microviscosity Does a Molecule Experience During its Rotational and Translational Diffusion in Crowded Environments? Biophysical Journal. 106: 736a. DOI: 10.1016/J.Bpj.2013.11.4056  0.461
2014 Alfveby J, Timerman R, Bartusek J, Wickramasinghe D, Israelson H, Heikal A. Two-Photon Fluorescence Lifetime Imaging of Natural Coenzymes in Living Cells as a Function of Oxidative Stress Biophysical Journal. 106: 185a. DOI: 10.1016/J.Bpj.2013.11.1044  0.379
2013 Fransen T, Soto Velasquez M, Welty R, Wickramasinghe D, Heikal A. Experimental and Simulation Analysis of NADH-Enzymes Binding in a Crowded Environment Biophysical Journal. 104: 304a. DOI: 10.1016/J.Bpj.2012.11.1690  0.418
2009 Yu Q, Heikal AA. Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level. Journal of Photochemistry and Photobiology. B, Biology. 95: 46-57. PMID 19179090 DOI: 10.1016/J.Jphotobiol.2008.12.010  0.736
2009 Yu Q, Heikal AA. Noninvasive Approach For Quantitative Analysis Of Energy Metabolism And Mitochondrial Anomalies In Living Cells Biophysical Journal. 96: 240a-241a. DOI: 10.1016/J.Bpj.2008.12.1184  0.752
2008 Yu Q, Proia M, Heikal AA. Integrated biophotonics approach for noninvasive and multiscale studies of biomolecular and cellular biophysics. Journal of Biomedical Optics. 13: 041315. PMID 19021323 DOI: 10.1117/1.2952297  0.788
2008 Davey AM, Krise KM, Sheets ED, Heikal AA. Molecular perspective of antigen-mediated mast cell signaling. The Journal of Biological Chemistry. 283: 7117-27. PMID 18093971 DOI: 10.1074/Jbc.M708879200  0.697
2007 Davey AM, Walvick RP, Liu Y, Heikal AA, Sheets ED. Membrane order and molecular dynamics associated with IgE receptor cross-linking in mast cells. Biophysical Journal. 92: 343-55. PMID 17040981 DOI: 10.1529/Biophysj.106.088815  0.727
2006 Liu Y, Kim HR, Heikal AA. Structural basis of fluorescence fluctuation dynamics of green fluorescent proteins in acidic environments. The Journal of Physical Chemistry. B. 110: 24138-46. PMID 17125385 DOI: 10.1021/jp062164t  0.402
2006 Ariola FS, Mudaliar DJ, Walvick RP, Heikal AA. Dynamics imaging of lipid phases and lipid-marker interactions in model biomembranes. Physical Chemistry Chemical Physics : Pccp. 8: 4517-29. PMID 17047749 DOI: 10.1039/b608629b  0.315
2005 Vishwasrao HD, Heikal AA, Kasischke KA, Webb WW. Conformational dependence of intracellular NADH on metabolic state revealed by associated fluorescence anisotropy. The Journal of Biological Chemistry. 280: 25119-26. PMID 15863500 DOI: 10.1074/Jbc.M502475200  0.37
2004 Korlach J, Baird DW, Heikal AA, Gee KR, Hoffman GR, Webb WW. Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled gamma-phosphate-linked GTP analogs. Proceedings of the National Academy of Sciences of the United States of America. 101: 2800-5. PMID 14973186 DOI: 10.1073/Pnas.0308579100  0.365
2004 Hess ST, Heikal AA, Webb WW. Fluorescence Photoconversion Kinetics in Novel Green Fluorescent Protein pH Sensors (pHluorins) The Journal of Physical Chemistry B. 108: 10138-10148. DOI: 10.1021/Jp0362077  0.39
2003 Hess ST, Sheets ED, Wagenknecht-Wiesner A, Heikal AA. Quantitative analysis of the fluorescence properties of intrinsically fluorescent proteins in living cells. Biophysical Journal. 85: 2566-80. PMID 14507719 DOI: 10.1016/S0006-3495(03)74679-7  0.753
2002 Hess ST, Huang S, Heikal AA, Webb WW. Biological and chemical applications of fluorescence correlation spectroscopy: a review. Biochemistry. 41: 697-705. PMID 11790090 DOI: 10.1021/Bi0118512  0.327
2002 Heikal AA, Webb WW. Multiphoton fluorescence microscopy in biology Proceedings of Spie - the International Society For Optical Engineering. 4812: 1-14. DOI: 10.1117/12.451382  0.409
2001 Heikal AA, Hess ST, Webb WW. Multiphoton molecular spectroscopy and excited-state dynamics of enhanced green fluorescent protein (EGFP): Acid-base specificity Chemical Physics. 274: 37-55. DOI: 10.1016/S0301-0104(01)00486-4  0.427
2000 Heikal AA, Hess ST, Baird GS, Tsien RY, Webb WW. Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: coral red (dsRed) and yellow (Citrine). Proceedings of the National Academy of Sciences of the United States of America. 97: 11996-2001. PMID 11050231 DOI: 10.1073/Pnas.97.22.11996  0.467
2000 Schwille P, Kummer S, Heikal AA, Moerner WE, Webb WW. Fluorescence correlation spectroscopy reveals fast optical excitation-driven intramolecular dynamics of yellow fluorescent proteins. Proceedings of the National Academy of Sciences of the United States of America. 97: 151-6. PMID 10618386 DOI: 10.1073/Pnas.97.1.151  0.414
1995 Kim SK, Breen JJ, Willberg DM, Peng LW, Heikal A, Syage JA, Zewail AH. Solvation Ultrafast Dynamics of Reactions. 8. Acid-Base Reactions in Finite-Sized Clusters of Naphthol in Ammonia, Water, and Piperidine The Journal of Physical Chemistry. 99: 7421-7435. DOI: 10.1021/J100019A027  0.318
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