Qinghai Zhang, Ph.D. - Publications

Affiliations: 
Molecular Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Self-assembling membrane mimics
Website:
http://www.scripps.edu/research/faculty/qzhang

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Padayatti PS, Lee SC, Stanfield RL, Wen PC, Tajkhorshid E, Wilson IA, Zhang Q. Structural Insights into the Lipid A Transport Pathway in MsbA. Structure (London, England : 1993). PMID 31130486 DOI: 10.1016/J.Str.2019.04.007  0.32
2017 Ishchenko A, Peng L, Zinovev E, Vlasov A, Lee SC, Kuklin A, Mishin A, Borshchevskiy V, Zhang Q, Cherezov V. Chemically Stable Lipids for Membrane Protein Crystallization. Crystal Growth & Design. 17: 3502-3511. PMID 29290736 DOI: 10.1021/Acs.Cgd.7B00458  0.304
2016 Shah MB, Jang HH, Wilderman PR, Lee D, Li S, Zhang Q, Stout CD, Halpert JR. Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophysical Chemistry. 216: 1-8. PMID 27280734 DOI: 10.1016/J.Bpc.2016.05.007  0.309
2016 Shah MB, Liu J, Huo L, Zhang Q, Dearing MD, Wilderman PR, Szklarz GD, Stout CD, Halpert JR. Structure-Function Analysis of Mammalian CYP2B Enzymes using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism. Molecular Pharmacology. PMID 26826176 DOI: 10.1124/Mol.115.102111  0.301
2015 Moeller A, Lee SC, Tao H, Speir JA, Chang G, Urbatsch IL, Potter CS, Carragher B, Zhang Q. Distinct conformational spectrum of homologous multidrug ABC transporters. Structure (London, England : 1993). 23: 450-60. PMID 25661651 DOI: 10.1016/J.Str.2014.12.013  0.31
2015 Shah MB, Wilderman PR, Liu J, Jang HH, Zhang Q, Stout CD, Halpert JR. Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison. Molecular Pharmacology. 87: 649-59. PMID 25585967 DOI: 10.1124/Mol.114.097014  0.308
2014 Hildebrandt E, Zhang Q, Cant N, Ding H, Dai Q, Peng L, Fu Y, DeLucas LJ, Ford R, Kappes JC, Urbatsch IL. A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR). Biochimica Et Biophysica Acta. 1838: 2825-37. PMID 25065669 DOI: 10.1016/J.Bbamem.2014.07.016  0.305
2013 Lee SC, Bennett BC, Hong WX, Fu Y, Baker KA, Marcoux J, Robinson CV, Ward AB, Halpert JR, Stevens RC, Stout CD, Yeager MJ, Zhang Q. Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: E1203-11. PMID 23479627 DOI: 10.1073/Pnas.1221442110  0.322
2013 Zhang H, Gay SC, Shah M, Foroozesh M, Liu J, Osawa Y, Zhang Q, Stout CD, Halpert JR, Hollenberg PF. Potent mechanism-based inactivation of cytochrome P450 2B4 by 9-ethynylphenanthrene: Implications for allosteric modulation of cytochrome P450 catalysis Biochemistry. 52: 355-364. PMID 23276288 DOI: 10.1021/Bi301567Z  0.311
2012 Tao H, Fu Y, Thompson A, Lee SC, Mahoney N, Stevens RC, Zhang Q. Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 11173-81. PMID 22780816 DOI: 10.1021/La3020404  0.321
2012 Wilderman PR, Gay SC, Jang HH, Zhang Q, Stout CD, Halpert JR. Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme. The Febs Journal. 279: 1607-20. PMID 22051155 DOI: 10.1111/J.1742-4658.2011.08411.X  0.301
2010 Gay SC, Roberts AG, Maekawa K, Talakad JC, Hong WX, Zhang Q, Stout CD, Halpert JR. Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel . Biochemistry. 49: 8709-20. PMID 20815363 DOI: 10.1021/Bi100914Z  0.308
2010 Annalora AJ, Goodin DB, Hong WX, Zhang Q, Johnson EF, Stout CD. Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. Journal of Molecular Biology. 396: 441-51. PMID 19961857 DOI: 10.1016/J.Jmb.2009.11.057  0.305
2010 Zhang Q, Lu X, Han X. ChemInform Abstract: Palladium(II)-Catalyzed Asymmetric Cyclization of (Z)-4′-Acetoxy-2′-butenyl 2-Alkynoates. Role of Nitrogen-Containing Ligands in Palladium(II)-Mediated Reactions. Cheminform. 33: no-no. DOI: 10.1002/chin.200218104  0.455
2010 Zhang Z, Lu X, Xu Z, Zhang Q, Han X. ChemInform Abstract: Role of Halide Ions in Divalent Palladium-Mediated Reactions: Competition Between β-Heteroatom Elimination and β-Hydride Elimination of a Carbon-Palladium Bond. Cheminform. 32: no-no. DOI: 10.1002/chin.200150031  0.447
2007 Stewart CR, Wilson LM, Zhang Q, Pham CL, Waddington LJ, Staples MK, Stapleton D, Kelly JW, Howlett GJ. Oxidized cholesterol metabolites found in human atherosclerotic lesions promote apolipoprotein C-II amyloid fibril formation. Biochemistry. 46: 5552-61. PMID 17429947 DOI: 10.1021/Bi602554Z  0.561
2006 Bieschke J, Zhang Q, Bosco DA, Lerner RA, Powers ET, Wentworth P, Kelly JW. Small molecule oxidation products trigger disease-associated protein misfolding. Accounts of Chemical Research. 39: 611-9. PMID 16981677 DOI: 10.1021/Ar0500766  0.733
2006 Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nature Chemical Biology. 2: 249-53. PMID 16565714 DOI: 10.1038/Nchembio782  0.726
2006 Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. Correction: Corrigendum: Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate α-synuclein fibrilization Nature Chemical Biology. 2: 346-346. DOI: 10.1038/Nchembio0606-346B  0.719
2005 Zhang Q, Kelly JW. Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice? Biochemistry. 44: 9079-85. PMID 15966731 DOI: 10.1021/Bi050378F  0.53
2005 Bieschke J, Zhang Q, Powers ET, Lerner RA, Kelly JW. Oxidative metabolites accelerate Alzheimer's amyloidogenesis by a two-step mechanism, eliminating the requirement for nucleation. Biochemistry. 44: 4977-83. PMID 15794636 DOI: 10.1021/Bi0501030  0.748
2005 Zhang Q, Xu W, Lu X. Cycloisomerization of 1,6-enynes using acetate as a nucleophile under palladium(II) catalysis. The Journal of Organic Chemistry. 70: 1505-7. PMID 15704997 DOI: 10.1021/Jo048414O  0.511
2004 Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P, Lerner RA, Kelly JW. Metabolite-initiated protein misfolding may trigger Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 4752-7. PMID 15034169 DOI: 10.1073/Pnas.0400924101  0.714
2003 Zhang Q, Kelly JW. Cys10 mixed disulfides make transthyretin more amyloidogenic under mildly acidic conditions. Biochemistry. 42: 8756-61. PMID 12873136 DOI: 10.1021/Bi030077A  0.482
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