Jean Pierre Julien, PhD - Publications


178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mishra PS, Boutej H, Soucy G, Bareil C, Kumar S, Picher-Martel V, Dupré N, Kriz J, Julien JP. Transmission of ALS pathogenesis by the cerebrospinal fluid. Acta Neuropathologica Communications. 8: 65. PMID 32381112 DOI: 10.1186/s40478-020-00943-4  0.32
2019 Pozzi S, Thammisetty SS, Codron P, Rahimian R, Plourde KV, Soucy G, Bareil C, Phaneuf D, Kriz J, Gravel C, Julien JP. Viral-mediated delivery of antibody targeting TAR DNA-binding protein 43 mitigates associated neuropathology. The Journal of Clinical Investigation. PMID 30667370 DOI: 10.1172/JCI123931  0.32
2016 Yadav P, Selvaraj BT, Bender FL, Behringer M, Moradi M, Sivadasan R, Dombert B, Blum R, Asan E, Sauer M, Julien JP, Sendtner M. Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling. Acta Neuropathologica. PMID 27021905 DOI: 10.1007/s00401-016-1564-y  0.88
2015 Ghasemlou N, Chiu IM, Julien JP, Woolf CJ. CD11b+Ly6G- myeloid cells mediate mechanical inflammatory pain hypersensitivity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598697 DOI: 10.1073/pnas.1501372112  0.88
2015 MacNair L, Xiao S, Miletic D, Ghani M, Julien JP, Keith J, Zinman L, Rogaeva E, Robertson J. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 26525917 DOI: 10.1093/brain/awv308  0.88
2015 Picher-Martel V, Dutta K, Phaneuf D, Sobue G, Julien JP. Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells. Molecular Brain. 8: 71. PMID 26521126 DOI: 10.1186/s13041-015-0162-6  0.88
2015 Correia AS, Patel P, Dutta K, Julien JP. Inflammation Induces TDP-43 Mislocalization and Aggregation. Plos One. 10: e0140248. PMID 26444430 DOI: 10.1371/journal.pone.0140248  0.88
2015 Yuan A, Hassinger L, Rao MV, Julien JP, Miller CC, Nixon RA. Dissociation of Axonal Neurofilament Content from Its Transport Rate. Plos One. 10: e0133848. PMID 26208164 DOI: 10.1371/journal.pone.0133848  0.88
2015 Yuan A, Sershen H, Veeranna, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee JH, Sato Y, Rao MV, Mohan PS, Dyakin V, Julien JP, Lee VM, Nixon RA. Functions of neurofilaments in synapses. Molecular Psychiatry. 20: 915. PMID 26201270 DOI: 10.1038/mp.2015.99  0.88
2015 Froud KE, Wong AC, Cederholm JM, Klugmann M, Sandow SL, Julien JP, Ryan AF, Housley GD. Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. Nature Communications. 6: 7115. PMID 25965946 DOI: 10.1038/ncomms8115  0.88
2015 Yuan A, Sershen H, Veeranna, Basavarajappa BS, Kumar A, Hashim A, Berg M, Lee JH, Sato Y, Rao MV, Mohan PS, Dyakin V, Julien JP, Lee VM, Nixon RA. Neurofilament subunits are integral components of synapses and modulate neurotransmission and behavior in vivo. Molecular Psychiatry. PMID 25869803 DOI: 10.1038/mp.2015.45  0.88
2015 Arbour D, Tremblay E, Martineau É, Julien JP, Robitaille R. Early and persistent abnormal decoding by glial cells at the neuromuscular junction in an ALS model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 688-706. PMID 25589763 DOI: 10.1523/JNEUROSCI.1379-14.2015  0.88
2015 Patel P, Julien JP, Kriz J. Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 217-33. PMID 25404049 DOI: 10.1007/s13311-014-0311-0  0.88
2014 Roche SL, Sherman DL, Dissanayake K, Soucy G, Desmazieres A, Lamont DJ, Peles E, Julien JP, Wishart TM, Ribchester RR, Brophy PJ, Gillingwater TH. Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12904-18. PMID 25232125 DOI: 10.1523/JNEUROSCI.1725-14.2014  0.88
2014 Ohta Y, Tremblay C, Schneider JA, Bennett DA, Calon F, Julien JP. Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits. Acta Neuropathologica Communications. 2: 37. PMID 24690380 DOI: 10.1186/2051-5960-2-37  0.88
2014 Patel P, Kriz J, Gravel M, Soucy G, Bareil C, Gravel C, Julien JP. Adeno-associated virus-mediated delivery of a recombinant single-chain antibody against misfolded superoxide dismutase for treatment of amyotrophic lateral sclerosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 498-510. PMID 24394188 DOI: 10.1038/mt.2013.239  0.88
2013 Saxena S, Roselli F, Singh K, Leptien K, Julien JP, Gros-Louis F, Caroni P. Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 80: 80-96. PMID 24094105 DOI: 10.1016/j.neuron.2013.07.027  0.88
2013 Pickles S, Destroismaisons L, Peyrard SL, Cadot S, Rouleau GA, Brown RH, Julien JP, Arbour N, Vande Velde C. Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1. Human Molecular Genetics. 22: 3947-59. PMID 23736301 DOI: 10.1093/hmg/ddt249  0.88
2013 Mahammad S, Murthy SN, Didonna A, Grin B, Israeli E, Perrot R, Bomont P, Julien JP, Kuczmarski E, Opal P, Goldman RD. Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation. The Journal of Clinical Investigation. 123: 1964-75. PMID 23585478 DOI: 10.1172/JCI66387  0.88
2013 Millecamps S, Julien JP. Axonal transport deficits and neurodegenerative diseases. Nature Reviews. Neuroscience. 14: 161-76. PMID 23361386 DOI: 10.1038/nrn3380  0.88
2012 Swarup V, Audet JN, Phaneuf D, Kriz J, Julien JP. Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18186-95. PMID 23238732 DOI: 10.1523/JNEUROSCI.2267-12.2012  0.88
2012 Yuan A, Sasaki T, Kumar A, Peterhoff CM, Rao MV, Liem RK, Julien JP, Nixon RA. Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8501-8. PMID 22723690 DOI: 10.1523/JNEUROSCI.1081-12.2012  0.88
2012 Audet JN, Gowing G, Paradis R, Soucy G, Julien JP. Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase. Plos One. 7: e34932. PMID 22523565 DOI: 10.1371/journal.pone.0034932  0.88
2012 Brotherton TE, Li Y, Cooper D, Gearing M, Julien JP, Rothstein JD, Boylan K, Glass JD. Localization of a toxic form of superoxide dismutase 1 protein to pathologically affected tissues in familial ALS. Proceedings of the National Academy of Sciences of the United States of America. 109: 5505-10. PMID 22431618 DOI: 10.1073/pnas.1115009109  0.88
2012 Audet JN, Soucy G, Julien JP. Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models. Neuroscience. 209: 136-43. PMID 22230045 DOI: 10.1016/j.neuroscience.2011.12.047  0.88
2012 Gentil BJ, Minotti S, Beange M, Baloh RH, Julien JP, Durham HD. Normal role of the low-molecular-weight neurofilament protein in mitochondrial dynamics and disruption in Charcot-Marie-Tooth disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1194-203. PMID 22155564 DOI: 10.1096/fj.11-196345  0.88
2012 Perrot R, Julien JP. Neurodegenerative diseases and intermediate filaments Cytoskeleton and Human Disease. 2147483647: 425-448. DOI: 10.1007/978-1-61779-788-0_20  0.88
2011 Swarup V, Phaneuf D, Dupré N, Petri S, Strong M, Kriz J, Julien JP. Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways. The Journal of Experimental Medicine. 208: 2429-47. PMID 22084410 DOI: 10.1084/jem.20111313  0.88
2011 Vande Velde C, McDonald KK, Boukhedimi Y, McAlonis-Downes M, Lobsiger CS, Bel Hadj S, Zandona A, Julien JP, Shah SB, Cleveland DW. Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset. Plos One. 6: e22031. PMID 21779368 DOI: 10.1371/journal.pone.0022031  0.88
2011 Swarup V, Phaneuf D, Bareil C, Robertson J, Rouleau GA, Kriz J, Julien JP. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain : a Journal of Neurology. 134: 2610-26. PMID 21752789 DOI: 10.1093/brain/awr159  0.88
2011 Rao MV, Mohan PS, Kumar A, Yuan A, Montagna L, Campbell J, Veeranna, Espreafico EM, Julien JP, Nixon RA. The myosin Va head domain binds to the neurofilament-L rod and modulates endoplasmic reticulum (ER) content and distribution within axons. Plos One. 6: e17087. PMID 21359212 DOI: 10.1371/journal.pone.0017087  0.88
2011 Filali M, Dequen F, Lalonde R, Julien JP. Sensorimotor and cognitive function of a NEFL(P22S) mutant model of Charcot-Marie-Tooth disease type 2E. Behavioural Brain Research. 219: 175-80. PMID 21168446 DOI: 10.1016/j.bbr.2010.12.022  0.88
2011 Swarup V, Julien JP. ALS pathogenesis: recent insights from genetics and mouse models. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 363-9. PMID 20728492 DOI: 10.1016/j.pnpbp.2010.08.006  0.88
2011 Dequen F, Cairns NJ, Bigio EH, Julien JP. Gigaxonin mutation analysis in patients with NIFID. Neurobiology of Aging. 32: 1528-9. PMID 19782434 DOI: 10.1016/j.neurobiolaging.2009.08.018  0.88
2010 Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nature Neuroscience. 13: 1396-403. PMID 20953194 DOI: 10.1038/nn.2660  0.88
2010 Takeuchi S, Fujiwara N, Ido A, Oono M, Takeuchi Y, Tateno M, Suzuki K, Takahashi R, Tooyama I, Taniguchi N, Julien JP, Urushitani M. Induction of protective immunity by vaccination with wild-type apo superoxide dismutase 1 in mutant SOD1 transgenic mice. Journal of Neuropathology and Experimental Neurology. 69: 1044-56. PMID 20838241 DOI: 10.1097/NEN.0b013e3181f4a90a  0.88
2010 Ezzi SA, Larivière R, Urushitani M, Julien JP. Neuronal over-expression of chromogranin A accelerates disease onset in a mouse model of ALS. Journal of Neurochemistry. 115: 1102-11. PMID 20807312 DOI: 10.1111/j.1471-4159.2010.06979.x  0.88
2010 Audet JN, Gowing G, Julien JP. Wild-type human SOD1 overexpression does not accelerate motor neuron disease in mice expressing murine Sod1 G86R. Neurobiology of Disease. 40: 245-50. PMID 20573565 DOI: 10.1016/j.nbd.2010.05.031  0.88
2010 Dequen F, Filali M, Larivière RC, Perrot R, Hisanaga S, Julien JP. Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E. Human Molecular Genetics. 19: 2616-29. PMID 20421365 DOI: 10.1093/hmg/ddq149  0.88
2010 Gros-Louis F, Soucy G, Larivière R, Julien JP. Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS. Journal of Neurochemistry. 113: 1188-99. PMID 20345765 DOI: 10.1111/j.1471-4159.2010.06683.x  0.88
2010 Barclay M, Julien JP, Ryan AF, Housley GD. Type III intermediate filament peripherin inhibits neuritogenesis in type II spiral ganglion neurons in vitro. Neuroscience Letters. 478: 51-5. PMID 20132868 DOI: 10.1016/j.neulet.2010.01.063  0.88
2010 Zhao W, Beers DR, Henkel JS, Zhang W, Urushitani M, Julien JP, Appel SH. Extracellular mutant SOD1 induces microglial-mediated motoneuron injury. Glia. 58: 231-43. PMID 19672969 DOI: 10.1002/glia.20919  0.88
2010 Gros-Louis F, Andersen PM, Rouleau GA, Julien JP. Reply to van Vught et al.: P413L CHGB as risk factor for ALS Proceedings of the National Academy of Sciences of the United States of America. 107: E78. DOI: 10.1073/pnas.1003411107  0.88
2009 Gros-Louis F, Andersen PM, Dupre N, Urushitani M, Dion P, Souchon F, D'Amour M, Camu W, Meininger V, Bouchard JP, Rouleau GA, Julien JP. Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 21777-82. PMID 20007371 DOI: 10.1073/pnas.0902174106  0.88
2009 Gowing G, Lalancette-Hébert M, Audet JN, Dequen F, Julien JP. Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase. Experimental Neurology. 220: 267-75. PMID 19733170 DOI: 10.1016/j.expneurol.2009.08.021  0.88
2009 Perrot R, Julien JP. Real-time imaging reveals defects of fast axonal transport induced by disorganization of intermediate filaments. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3213-25. PMID 19451279 DOI: 10.1096/fj.09-129585  0.88
2009 Mckerracher L, Julien JP, Aguayo AJ. Role of cellular interactions in axonal growth and regeneration The Axon: Structure, Function and Pathophysiology. DOI: 10.1093/acprof:oso/9780195082937.003.0029  0.88
2008 Gowing G, Philips T, Van Wijmeersch B, Audet JN, Dewil M, Van Den Bosch L, Billiau AD, Robberecht W, Julien JP. Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10234-44. PMID 18842883 DOI: 10.1523/JNEUROSCI.3494-08.2008  0.88
2008 Barrette B, Hébert MA, Filali M, Lafortune K, Vallières N, Gowing G, Julien JP, Lacroix S. Requirement of myeloid cells for axon regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9363-76. PMID 18799670 DOI: 10.1523/JNEUROSCI.1447-08.2008  0.88
2008 Dequen F, Bomont P, Gowing G, Cleveland DW, Julien JP. Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1. Journal of Neurochemistry. 107: 253-64. PMID 18680552 DOI: 10.1111/j.1471-4159.2008.05601.x  0.88
2008 Gros-Louis F, Kriz J, Kabashi E, McDearmid J, Millecamps S, Urushitani M, Lin L, Dion P, Zhu Q, Drapeau P, Julien JP, Rouleau GA. Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Human Molecular Genetics. 17: 2691-702. PMID 18558633 DOI: 10.1093/hmg/ddn171  0.88
2008 Urushitani M, Ezzi SA, Matsuo A, Tooyama I, Julien JP. The endoplasmic reticulum-Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2476-87. PMID 18337461 DOI: 10.1096/fj.07-092783  0.88
2008 Eriksson KS, Zhang S, Lin L, Larivière RC, Julien JP, Mignot E. The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse. Bmc Neuroscience. 9: 26. PMID 18294400 DOI: 10.1186/1471-2202-9-26  0.4
2008 Millecamps S, Julien JP. [Dysfunction of axonal transport in neuropathies and motor neuron diseases]. MéDecine Sciences : M/S. 24: 65-71. PMID 18198113 DOI: 10.1051/medsci/200824165  0.88
2007 Julien JP, Kriz J. Chapter 6 Animal models of motor neuron death. Handbook of Clinical Neurology. 82: 121-38. PMID 18808891 DOI: 10.1016/S0072-9752(07)80009-1  0.88
2007 Barclay M, Noakes PG, Ryan AF, Julien JP, Housley GD. Neuronal expression of peripherin, a type III intermediate filament protein, in the mouse hindbrain. Histochemistry and Cell Biology. 128: 541-50. PMID 17899157 DOI: 10.1007/s00418-007-0340-4  0.88
2007 Zhai J, Lin H, Julien JP, Schlaepfer WW. Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1. Human Molecular Genetics. 16: 3103-16. PMID 17881652 DOI: 10.1093/hmg/ddm272  0.88
2007 Galarneau H, Villeneuve J, Gowing G, Julien JP, Vallières L. Increased glioma growth in mice depleted of macrophages. Cancer Research. 67: 8874-81. PMID 17875729 DOI: 10.1158/0008-5472.CAN-07-0177  0.88
2007 Millecamps S, Gowing G, Corti O, Mallet J, Julien JP. Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4947-56. PMID 17475803 DOI: 10.1523/JNEUROSCI.5299-06.2007  0.88
2007 Julien JP. ALS: astrocytes move in as deadly neighbors. Nature Neuroscience. 10: 535-7. PMID 17453052 DOI: 10.1038/nn0507-535  0.88
2007 Barry DM, Millecamps S, Julien JP, Garcia ML. New movements in neurofilament transport, turnover and disease. Experimental Cell Research. 313: 2110-20. PMID 17451679 DOI: 10.1016/j.yexcr.2007.03.011  0.88
2007 Ezzi SA, Urushitani M, Julien JP. Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. Journal of Neurochemistry. 102: 170-8. PMID 17394546 DOI: 10.1111/j.1471-4159.2007.04531.x  0.88
2007 Urushitani M, Ezzi SA, Julien JP. Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 2495-500. PMID 17277077 DOI: 10.1073/pnas.0606201104  0.88
2007 Haenggeli C, Julien JP, Mosley RL, Perez N, Dhar A, Gendelman HE, Rothstein JD. Therapeutic immunization with a glatiramer acetate derivative does not alter survival in G93A and G37R SOD1 mouse models of familial ALS. Neurobiology of Disease. 26: 146-52. PMID 17276077 DOI: 10.1016/j.nbd.2006.12.013  0.88
2007 Julien JP. Mouse models of amyotrophic lateral sclerosis Drug Discovery Today: Disease Models. 3: 331-339. DOI: 10.1016/j.ddmod.2006.12.003  0.88
2006 Gowing G, Dequen F, Soucy G, Julien JP. Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11397-402. PMID 17079668 DOI: 10.1523/JNEUROSCI.0602-06.2006  0.88
2006 Yuan A, Rao MV, Sasaki T, Chen Y, Kumar A, Veeranna, Liem RK, Eyer J, Peterson AC, Julien JP, Nixon RA. Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10006-19. PMID 17005864 DOI: 10.1523/JNEUROSCI.2580-06.2006  0.88
2006 Millecamps S, Robertson J, Lariviere R, Mallet J, Julien JP. Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. Journal of Neurochemistry. 98: 926-38. PMID 16787413 DOI: 10.1111/j.1471-4159.2006.03932.x  0.88
2006 Carmen J, Gowing G, Julien JP, Kerr D. Altered immune response to CNS viral infection in mice with a conditional knock-down of macrophage-lineage cells. Glia. 54: 71-80. PMID 16691560 DOI: 10.1002/glia.20359  0.88
2006 Julien JP, Kriz J. Transgenic mouse models of amyotrophic lateral sclerosis. Biochimica Et Biophysica Acta. 1762: 1013-24. PMID 16675207 DOI: 10.1016/j.bbadis.2006.03.006  0.88
2006 Simard AR, Soulet D, Gowing G, Julien JP, Rivest S. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron. 49: 489-502. PMID 16476660 DOI: 10.1016/j.neuron.2006.01.022  0.88
2006 Sasaki T, Gotow T, Shiozaki M, Sakaue F, Saito T, Julien JP, Uchiyama Y, Hisanaga S. Aggregate formation and phosphorylation of neurofilament-L Pro22 Charcot-Marie-Tooth disease mutants. Human Molecular Genetics. 15: 943-52. PMID 16452125 DOI: 10.1093/hmg/ddl011  0.88
2006 Urushitani M, Sik A, Sakurai T, Nukina N, Takahashi R, Julien JP. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nature Neuroscience. 9: 108-18. PMID 16369483 DOI: 10.1038/nn1603  0.88
2006 Gowing G, Vallières L, Julien JP. Mouse model for ablation of proliferating microglia in acute CNS injuries. Glia. 53: 331-7. PMID 16276506 DOI: 10.1002/glia.20288  0.88
2006 Veglianese P, Lo Coco D, Bao Cutrona M, Magnoni R, Pennacchini D, Pozzi B, Gowing G, Julien JP, Tortarolo M, Bendotti C. Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS. Molecular and Cellular Neurosciences. 31: 218-31. PMID 16219474 DOI: 10.1016/j.mcn.2005.09.009  0.88
2005 Jung C, Lee S, Ortiz D, Zhu Q, Julien JP, Shea TB. The high and middle molecular weight neurofilament subunits regulate the association of neurofilaments with kinesin: inhibition by phosphorylation of the high molecular weight subunit. Brain Research. Molecular Brain Research. 141: 151-5. PMID 16246456 DOI: 10.1016/j.molbrainres.2005.08.009  0.88
2005 Millecamps S, Gentil BJ, Gros-Louis F, Rouleau G, Julien JP. Alsin is partially associated with centrosome in human cells. Biochimica Et Biophysica Acta. 1745: 84-100. PMID 16085057 DOI: 10.1016/j.bbamcr.2004.12.008  0.88
2005 Dubois M, Strazielle C, Julien JP, Lalonde R. Mice with the deleted neurofilament of low molecular weight (Nefl) gene: 2. Effects on motor functions and spatial orientation. Journal of Neuroscience Research. 80: 751-8. PMID 15884021 DOI: 10.1002/jnr.20493  0.88
2005 Julien JP, Millecamps S, Kriz J. Cytoskeletal defects in amyotrophic lateral sclerosis (motor neuron disease). Novartis Foundation Symposium. 264: 183-92; discussion 1. PMID 15773754  0.88
2005 Dubois M, Lalonde R, Julien JP, Strazielle C. Mice with the deleted neurofilament of low-molecular-weight (Nefl) gene: 1. Effects on regional brain metabolism. Journal of Neuroscience Research. 80: 741-50. PMID 15742362 DOI: 10.1002/jnr.20449  0.88
2005 Kriz J, Beaulieu JM, Julien JP, Krnjević K. Up-regulation of peripherin is associated with alterations in synaptic plasticity in CA1 and CA3 regions of hippocampus. Neurobiology of Disease. 18: 409-20. PMID 15686970 DOI: 10.1016/j.nbd.2004.10.009  0.88
2005 Collas P, Stewart CL, Gruenbaum Y, Oshima J, Young SG, Fatkin D, Capeau J, Julien JP, Lévy N, Goldman A, Goldman RD, Davies K, Wilson KL, Gasser SM, Courvalin JC, et al. Discussion Novartis Foundation Symposium. 264: 258-263.  0.88
2005 Goldman A, Goldman RD, Capeau J, Wilson KL, Young SG, Fatkin D, Julien JP, Davies K, Gasser SM, Burke B, Oshima J, Lévy N, Stewart CL. General discussion I Novartis Foundation Symposium. 264: 227-230.  0.88
2005 Gasser SM, Oshima J, Goldman R, Stewart CL, Young SG, Burke BJ, Warner HR, Gerace L, Levy N, Hutchison C, Gruenbaum Y, Bonne G, Shumaker DK, Julien JP, Wilkins A. Discussion Novartis Foundation Symposium. 264: 202-207.  0.88
2005 Fatkin D, Wilson KL, Gruenbaum Y, Ellis J, Julien JP, Shumaker D, Goldman A, Morris GE, Gerace L, Wilkins A. Discussion Novartis Foundation Symposium. 264: 58-62.  0.88
2004 Millecamps S, Julien JP. [35S]Methionine metabolic labeling to study axonal transport of neuronal intermediate filament proteins in vivo. Methods in Cell Biology. 78: 555-71. PMID 15646631 DOI: 10.1016/S0091-679X(04)78019-X  0.88
2004 Gros-Louis F, Larivière R, Gowing G, Laurent S, Camu W, Bouchard JP, Meininger V, Rouleau GA, Julien JP. A frameshift deletion in peripherin gene associated with amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 279: 45951-6. PMID 15322088 DOI: 10.1074/jbc.M408139200  0.88
2004 Nguyen MD, Shu T, Sanada K, Larivière RC, Tseng HC, Park SK, Julien JP, Tsai LH. A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons. Nature Cell Biology. 6: 595-608. PMID 15208636 DOI: 10.1038/ncb1139  0.88
2004 Shalin SC, Zirrgiebel U, Honsa KJ, Julien JP, Miller FD, Kaplan DR, Sweatt JD. Neuronal MEK is important for normal fear conditioning in mice. Journal of Neuroscience Research. 75: 760-70. PMID 14994337 DOI: 10.1002/jnr.20052  0.88
2004 Zhang G, Spencer PH, Jin LQ, Cohlberg JA, Beaulieu JM, Julien JP, Selzer ME. The single neurofilament subunit of lamprey may need another element for filament assembly. The Journal of Comparative Neurology. 471: 188-200. PMID 14986312 DOI: 10.1002/cne.20026  0.88
2004 Nguyen MD, D'Aigle T, Gowing G, Julien JP, Rivest S. Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1340-9. PMID 14960605 DOI: 10.1523/JNEUROSCI.4786-03.2004  0.88
2004 Lariviere RC, Julien JP. Functions of intermediate filaments in neuronal development and disease. Journal of Neurobiology. 58: 131-48. PMID 14598376 DOI: 10.1002/neu.10270  0.88
2004 Julien JP. Animal models of motor neuron death Handbook of Clinical Neurophysiology. 4: 201-218. DOI: 10.1016/S1567-4231(04)04010-9  0.88
2003 Nguyen MD, Julien JP. Cyclin-dependent kinase 5 in amyotrophic lateral sclerosis. Neuro-Signals. 12: 215-20. PMID 14673208 DOI: 10.1159/000074623  0.88
2003 Dziarmaga A, Clark P, Stayner C, Julien JP, Torban E, Goodyer P, Eccles M. Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome. Journal of the American Society of Nephrology : Jasn. 14: 2767-74. PMID 14569086 DOI: 10.1097/01.ASN.0000094082.11026.EE  0.88
2003 Lizée G, Basha G, Tiong J, Julien JP, Tian M, Biron KE, Jefferies WA. Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nature Immunology. 4: 1065-73. PMID 14566337 DOI: 10.1038/ni989  0.88
2003 Yuan A, Rao MV, Kumar A, Julien JP, Nixon RA. Neurofilament transport in vivo minimally requires hetero-oligomer formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9452-8. PMID 14561875  0.88
2003 Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillée S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien JP, Goldstein LS, Cleveland DW. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (New York, N.Y.). 302: 113-7. PMID 14526083 DOI: 10.1126/science.1086071  0.88
2003 Larivière RC, Beaulieu JM, Nguyen MD, Julien JP. Peripherin is not a contributing factor to motor neuron disease in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase. Neurobiology of Disease. 13: 158-66. PMID 12828939 DOI: 10.1016/S0969-9961(03)00036-6  0.88
2003 Kriz J, Gowing G, Julien JP. Efficient three-drug cocktail for disease induced by mutant superoxide dismutase. Annals of Neurology. 53: 429-36. PMID 12666110 DOI: 10.1002/ana.10500  0.32
2003 Nguyen MD, Boudreau M, Kriz J, Couillard-Després S, Kaplan DR, Julien JP. Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2131-40. PMID 12657672  0.88
2003 Robertson J, Doroudchi MM, Nguyen MD, Durham HD, Strong MJ, Shaw G, Julien JP, Mushynski WE. A neurotoxic peripherin splice variant in a mouse model of ALS. The Journal of Cell Biology. 160: 939-49. PMID 12642616 DOI: 10.1083/jcb.200205027  0.88
2003 Beaulieu JM, Julien JP. Peripherin-mediated death of motor neurons rescued by overexpression of neurofilament NF-H proteins. Journal of Neurochemistry. 85: 248-56. PMID 12641746  0.88
2003 Farah CA, Nguyen MD, Julien JP, Leclerc N. Altered levels and distribution of microtubule-associated proteins before disease onset in a mouse model of amyotrophic lateral sclerosis. Journal of Neurochemistry. 84: 77-86. PMID 12485403  0.56
2003 Robertson J, Julien JP. Chapter 12 Cytoskeletal Abnormalities in Amyotrophic Lateral Sclerosis/Motor Neuron Disease Blue Books of Practical Neurology. 28: 315-339. DOI: 10.1016/S1877-3419(09)70113-8  0.88
2002 Robertson J, Kriz J, Nguyen MD, Julien JP. Pathways to motor neuron degeneration in transgenic mouse models. Biochimie. 84: 1151-60. PMID 12595144  0.56
2002 Nguyen MD, Mushynski WE, Julien JP. Cycling at the interface between neurodevelopment and neurodegeneration. Cell Death and Differentiation. 9: 1294-306. PMID 12478466 DOI: 10.1038/sj.cdd.4401108  0.88
2002 Rao MV, Engle LJ, Mohan PS, Yuan A, Qiu D, Cataldo A, Hassinger L, Jacobsen S, Lee VM, Andreadis A, Julien JP, Bridgman PC, Nixon RA. Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density. The Journal of Cell Biology. 159: 279-90. PMID 12403814 DOI: 10.1083/jcb.200205062  0.88
2002 Kriz J, Nguyen MD, Julien JP. Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiology of Disease. 10: 268-78. PMID 12270689  0.56
2002 Patel BN, Dunn RJ, Jeong SY, Zhu Q, Julien JP, David S. Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6578-86. PMID 12151537  0.88
2002 Beaulieu JM, Kriz J, Julien JP. Induction of peripherin expression in subsets of brain neurons after lesion injury or cerebral ischemia. Brain Research. 946: 153-61. PMID 12137917 DOI: 10.1016/S0006-8993(02)02830-5  0.88
2002 Larivière RC, Nguyen MD, Ribeiro-da-Silva A, Julien JP. Reduced number of unmyelinated sensory axons in peripherin null mice. Journal of Neurochemistry. 81: 525-32. PMID 12065660 DOI: 10.1046/j.1471-4159.2002.00853.x  0.88
2002 Nguyen MD, Julien JP, Rivest S. Innate immunity: the missing link in neuroprotection and neurodegeneration? Nature Reviews. Neuroscience. 3: 216-27. PMID 11994753 DOI: 10.1038/nrn752  0.88
2001 Nguyen MD, Julien JP, Rivest S. Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration. Annals of Neurology. 50: 630-9. PMID 11706969 DOI: 10.1002/ana.1256  0.88
2001 Robertson J, Beaulieu JM, Doroudchi MM, Durham HD, Julien JP, Mushynski WE. Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha. The Journal of Cell Biology. 155: 217-26. PMID 11604419 DOI: 10.1083/jcb.200107058  0.88
2001 Nguyen MD, Larivière RC, Julien JP. Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions. Neuron. 30: 135-47. PMID 11343650  0.56
2001 Julien JP. Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded. Cell. 104: 581-91. PMID 11239414 DOI: 10.1016/S0092-8674(01)00244-6  0.88
2000 Kriz J, Zhu Q, Julien JP, Padjen AL. Electrophysiological properties of axons in mice lacking neurofilament subunit genes: disparity between conduction velocity and axon diameter in absence of NF-H. Brain Research. 885: 32-44. PMID 11121527  0.32
2000 Julien JP, Beaulieu JM. Cytoskeletal abnormalities in amyotrophic lateral sclerosis: beneficial or detrimental effects? Journal of the Neurological Sciences. 180: 7-14. PMID 11090858 DOI: 10.1016/S0022-510X(00)00422-6  0.88
2000 Nguyen MD, Larivière RC, Julien JP. Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1. Proceedings of the National Academy of Sciences of the United States of America. 97: 12306-11. PMID 11050249 DOI: 10.1073/pnas.97.22.12306  0.88
2000 Beaulieu JM, Jacomy H, Julien JP. Formation of intermediate filament protein aggregates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5321-8. PMID 10884316  0.88
2000 Kriz J, Meier J, Julien JP, Padjen AL. Altered ionic conductances in axons of transgenic mouse expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis. Experimental Neurology. 163: 414-21. PMID 10833316 DOI: 10.1006/exnr.2000.7378  0.32
2000 McLeod AL, Ritchie J, Cuello AC, Julien JP, Henry JL, Ribeiro-da-Silva A. Upregulation of an opioid-mediated antinociceptive mechanism in transgenic mice over-expressing substance P in the spinal cord. Neuroscience. 96: 785-9. PMID 10727796 DOI: 10.1016/S0306-4522(99)00606-5  0.88
1999 Beaulieu JM, Nguyen MD, Julien JP. Late onset of motor neurons in mice overexpressing wild-type peripherin. The Journal of Cell Biology. 147: 531-44. PMID 15132161 DOI: 10.1083/jcb.147.3.531  0.88
1999 Meier J, Couillard-Després S, Jacomy H, Gravel C, Julien JP. Extra neurofilament NF-L subunits rescue motor neuron disease caused by overexpression of the human NF-H gene in mice. Journal of Neuropathology and Experimental Neurology. 58: 1099-110. PMID 10515233 DOI: 10.1097/00005072-199910000-00009  0.88
1999 Julien JP. Neurofilament functions in health and disease. Current Opinion in Neurobiology. 9: 554-60. PMID 10508735 DOI: 10.1016/S0959-4388(99)00004-5  0.88
1999 Jacomy H, Zhu Q, Couillard-Després S, Beaulieu JM, Julien JP. Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits. Journal of Neurochemistry. 73: 972-84. PMID 10461886 DOI: 10.1046/j.1471-4159.1999.0730972.x  0.88
1999 Yang Y, Bauer C, Strasser G, Wollman R, Julien JP, Fuchs E. Integrators of the cytoskeleton that stabilize microtubules. Cell. 98: 229-38. PMID 10428034 DOI: 10.1016/S0092-8674(00)81017-X  0.88
1999 Beaulieu JM, Robertson J, Julien JP. Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 41-5. PMID 10426285 DOI: 10.1139/bcb-77-1-41  0.88
1999 McLeod AL, Julien JP, Cuello AC, Krause JE, Ribeiro-da-Silva A. Ectopic substance P-immunoreactive boutons are preferentially presynaptic to neurokinin-1 receptor immunoreactive dendrites in the spinal white matter of transgenic mice. Brain Research. 836: 1-8. PMID 10415399 DOI: 10.1016/S0006-8993(99)01524-3  0.88
1999 Levavasseur F, Zhu Q, Julien JP. No requirement of alpha-internexin for nervous system development and for radial growth of axons. Brain Research. Molecular Brain Research. 69: 104-12. PMID 10350642 DOI: 10.1016/S0169-328X(99)00104-7  0.88
1999 Ma D, Descarries L, Micheva KD, Lepage Y, Julien JP, Doucet G. Severe neuronal losses with age in the parietal cortex and ventrobasal thalamus of mice transgenic for the human NF-L neurofilament protein. The Journal of Comparative Neurology. 406: 433-48. PMID 10205021 DOI: 10.1002/(SICI)1096-9861(19990419)406:4<433::AID-CNE2>3.0.CO;2-3  0.88
1999 McLeod AL, Ritchie J, Cuello AC, Julien JP, Ribeiro-Da-Silva A, Henry JL. Transgenic mice over-expressing substance P exhibit allodynia and hyperalgesia which are reversed by substance P and N-methyl-D-aspartate receptor antagonists. Neuroscience. 89: 891-9. PMID 10199622 DOI: 10.1016/S0306-4522(98)00365-0  0.88
1999 Zhu Q, Julien JP. A key role for GAP-43 in the retinotectal topographic organization. Experimental Neurology. 155: 228-42. PMID 10072298 DOI: 10.1006/exnr.1998.6989  0.88
1998 Zhu Q, Lindenbaum M, Levavasseur F, Jacomy H, Julien JP. Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile. The Journal of Cell Biology. 143: 183-93. PMID 9763430 DOI: 10.1083/jcb.143.1.183  0.88
1998 Julien JP, Mushynski WE. Neurofilaments in health and disease. Progress in Nucleic Acid Research and Molecular Biology. 61: 1-23. PMID 9752717  0.88
1998 Kawaja MD, Walsh GS, Tovich PR, Julien JP. Effects of elevated levels of nerve growth factor on the septohippocampal system in transgenic mice. The European Journal of Neuroscience. 10: 2207-16. PMID 9749749 DOI: 10.1046/j.1460-9568.1998.00228.x  0.88
1998 Williamson TL, Bruijn LI, Zhu Q, Anderson KL, Anderson SD, Julien JP, Cleveland DW. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proceedings of the National Academy of Sciences of the United States of America. 95: 9631-6. PMID 9689132 DOI: 10.1073/pnas.95.16.9631  0.32
1998 Couillard-Després S, Zhu Q, Wong PC, Price DL, Cleveland DW, Julien JP. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proceedings of the National Academy of Sciences of the United States of America. 95: 9626-30. PMID 9689131 DOI: 10.1073/pnas.95.16.9626  0.88
1997 Julien JP. Neurofilaments and motor neuron disease. Trends in Cell Biology. 7: 243-9. PMID 17708953 DOI: 10.1016/S0962-8924(97)01049-0  0.88
1997 Zhu Q, Couillard-Després S, Julien JP. Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments. Experimental Neurology. 148: 299-316. PMID 9398473 DOI: 10.1006/exnr.1997.6654  0.32
1997 Lazzaro MA, Julien JP. Chromosomal mapping of the PFTAIRE gene, Pftk1, a cdc2-related kinase expressed predominantly in the mouse nervous system. Genomics. 42: 536-7. PMID 9205131 DOI: 10.1006/geno.1997.4760  0.88
1997 Nalbantoglu J, Tirado-Santiago G, Lahsaïni A, Poirier J, Goncalves O, Verge G, Momoli F, Welner SA, Massicotte G, Julien JP, Shapiro ML. Impaired learning and LTP in mice expressing the carboxy terminus of the Alzheimer amyloid precursor protein. Nature. 387: 500-5. PMID 9168112 DOI: 10.1038/387500a0  0.88
1997 Tu PH, Gurney ME, Julien JP, Lee VM, Trojanowski JQ. Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 76: 441-56. PMID 9111507  0.88
1997 Kuchel GA, Poon T, Irshad K, Richard C, Julien JP, Cowen T. Decreased neurofilament gene expression is an index of selective axonal hypotrophy in ageing. Neuroreport. 8: 799-805. PMID 9106770  0.88
1996 Kuchel GA, Poon T, Irshad K, Richard C, Julien JP, Cowen T. Decreased neurofilament gene expression is an index of selective axonal hypotrophy in ageing. Neuroreport. 7: 1353-9. PMID 8856674  0.88
1996 Rouleau GA, Clark AW, Rooke K, Pramatarova A, Krizus A, Suchowersky O, Julien JP, Figlewicz D. SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. Annals of Neurology. 39: 128-31. PMID 8572658 DOI: 10.1002/ana.410390119  0.88
1995 Julien JP. A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 593-7. PMID 8714677  0.88
1995 Martinoli MG, Trojanowski JQ, Schmidt ML, Arnold SE, Fujiwara TM, Lee VM, Hurtig H, Julien JP, Clark C. Association of apolipoprotein epsilon 4 allele and neuropathologic findings in patients with dementia. Acta Neuropathologica. 90: 239-43. PMID 8525796 DOI: 10.1007/BF00296506  0.88
1995 Collard JF, Julien JP. A simple test to monitor the motor dysfunction in a transgenic mouse model of amyotrophic lateral sclerosis. Journal of Psychiatry & Neuroscience : Jpn. 20: 80-2. PMID 7865504  0.88
1995 Mathieu JF, Ma D, Descarries L, Vallée A, Parent A, Julien JP, Doucet G. CNS distribution and overexpression of neurofilament light proteins (NF-L) in mice transgenic for the human NF-L: aberrant accumulation in thalamic perikarya. Experimental Neurology. 132: 134-46. PMID 7720822 DOI: 10.1016/0014-4886(95)90067-5  0.88
1995 Ma D, Descarries L, Julien JP, Doucet G. Abnormal perikaryal accumulation of neurofilament light protein in the brain of mice transgenic for the human protein: sequence of postnatal development. Neuroscience. 68: 135-49. PMID 7477919 DOI: 10.1016/0306-4522(95)00088-Z  0.88
1995 Julien JP. Author's response to commentary Neurobiology of Aging. 16: 492. DOI: 10.1016/0197-4580(94)00171-V  0.88
1994 Figlewicz DA, Krizus A, Martinoli MG, Meininger V, Dib M, Rouleau GA, Julien JP. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Human Molecular Genetics. 3: 1757-61. PMID 7849698 DOI: 10.1093/hmg/3.10.1757  0.88
1993 Beaudet L, Côté F, Houle D, Julien JP. Different posttranscriptional controls for the human neurofilament light and heavy genes in transgenic mice. Brain Research. Molecular Brain Research. 18: 23-31. PMID 8479288 DOI: 10.1016/0169-328X(93)90170-T  0.88
1993 Figlewicz DA, Rouleau GA, Krizus A, Julien JP. Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene. Gene. 132: 297-300. PMID 8224877 DOI: 10.1016/0378-1119(93)90211-K  0.88
1993 Friedman HCH, Julien JP. Transgenic Mouse Approaches for Analysis of the Nervous System Neuroprotocols. 3: 69-80. DOI: 10.1006/ncmn.1993.1039  0.88
1992 Aubry M, Marineau C, Zhang FR, Zahed L, Figlewicz D, Delattre O, Thomas G, de Jong PJ, Julien JP, Rouleau GA. Cloning of six new genes with zinc finger motifs mapping to short and long arms of human acrocentric chromosome 22 (p and q11.2). Genomics. 13: 641-8. PMID 1639391 DOI: 10.1016/0888-7543(92)90135-F  0.88
1992 Beaudet L, Charron G, Houle D, Tretjakoff I, Peterson A, Julien JP. Intragenic regulatory elements contribute to transcriptional control of the neurofilament light gene. Gene. 116: 205-14. PMID 1634118 DOI: 10.1016/0378-1119(92)90517-S  0.88
1992 Beaudet L, Charron G, Julien JP. Origin of the two mRNA species for the human neurofilament light gene. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 70: 279-84. PMID 1497855  0.88
1991 Vidal-Sanz M, Villegas-Pérez MP, Carter DA, Julien JP, Peterson A, Aguayo AJ. Expression of Human Neurofilament-light Transgene in Mouse Neurons Transplanted into the Brain of Adult Rats. The European Journal of Neuroscience. 3: 758-763. PMID 12106461  0.88
1990 Julien JP, Beaudet L, Tretjakoff I, Peterson A. Neurofilament gene expression in transgenic mice. Journal De Physiologie. 84: 50-2. PMID 2359036  0.88
1990 Clark AW, Tran PM, Parhad IM, Krekoski CA, Julien JP. Neuronal gene expression in amyotrophic lateral sclerosis. Brain Research. Molecular Brain Research. 7: 75-83. PMID 2153897 DOI: 10.1016/0169-328X(90)90076-P  0.88
1990 Lacoste-Royal G, Mathieu M, Nalbantoglu J, Julien JP, Gauthier S, Gauvreau D. Lack of association between two restriction fragment length polymorphisms in the genes for the light and heavy neurofilament proteins and Alzheimer's disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 17: 302-5. PMID 1976427 DOI: 10.1017/S0317167100030614  0.88
1989 Clark AW, Krekoski CA, Parhad IM, Liston D, Julien JP, Hoar DI. Altered expression of neuronal messenger RNA in Alzheimer cortex. Progress in Clinical and Biological Research. 317: 511-5. PMID 2602430  0.88
1989 Clark AW, Krekoski CA, Parhad IM, Liston D, Julien JP, Hoar DI. Altered expression of genes for amyloid and cytoskeletal proteins in Alzheimer cortex. Annals of Neurology. 25: 331-9. PMID 2469380 DOI: 10.1002/ana.410250404  0.88
1988 Julien JP, Côté F, Beaudet L, Sidky M, Flavell D, Grosveld F, Mushynski W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit. Gene. 68: 307-14. PMID 3220257 DOI: 10.1016/0378-1119(88)90033-9  0.88
1987 Hurst J, Flavell D, Julien JP, Meijer D, Mushynski W, Grosveld F. The human neurofilament gene (NEFL) is located on the short arm of chromosome 8. Cytogenetics and Cell Genetics. 45: 30-2. PMID 3036423 DOI: 10.1159/000132421  0.88
1987 Julien JP, Grosveld F, Yazdanbaksh K, Flavell D, Meijer D, Mushynski W. The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament gene family. Biochimica Et Biophysica Acta. 909: 10-20. PMID 3034332 DOI: 10.1016/0167-4781(87)90041-8  0.88
1987 Julien JP, Tretjakoff I, Beaudet L, Peterson A. Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system. Genes & Development. 1: 1085-95. PMID 2828164  0.88
1986 Liesi P, Julien JP, Vilja P, Grosveld F, Rechardt L. Specific detection of neuronal cell bodies: in situ hybridization with a biotin-labeled neurofilament cDNA probe. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 34: 923-6. PMID 3458811  0.72
1986 Julien JP, Meyer D, Flavell D, Hurst J, Grosveld F. Cloning and developmental expression of the murine neurofilament gene family. Brain Research. 387: 243-50. PMID 3103856  0.72
1985 Julien JP, Ramachandran K, Grosveld F. Cloning of a cDNA encoding the smallest neurofilament protein from the rat. Biochimica Et Biophysica Acta. 825: 398-404. PMID 3925999  0.72
1983 Julien JP, Smoluk GD, Mushynski WE. Characteristics of the protein kinase activity associated with rat neurofilament preparations. Biochimica Et Biophysica Acta. 755: 25-31. PMID 6681714 DOI: 10.1016/0304-4165(83)90268-4  0.88
1983 Julien JP, Mushynski WE. The distribution of phosphorylation sites among identified proteolytic fragments of mammalian neurofilaments. The Journal of Biological Chemistry. 258: 4019-25. PMID 6339492  0.88
1982 Julien JP, Mushynski WE. Multiple phosphorylation sites in mammalian neurofilament polypeptides. The Journal of Biological Chemistry. 257: 10467-70. PMID 7202005  0.88
1981 Julien JP, Mushynski WE. A comparison of in vitro- and in vivo-phosphorylated neurofilament polypeptides. Journal of Neurochemistry. 37: 1579-85. PMID 7199562  0.88
1981 Julien JP, Mushynski WE, Duncan ID, Griffiths IR. Giant axonal neuropathy: neurofilaments isolated from diseased dogs have a normal polypeptide composition. Experimental Neurology. 72: 619-27. PMID 7195344 DOI: 10.1016/0014-4886(81)90010-8  0.88
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