Frank Grosveld - Publications

Erasmus Medical Center Rotterdam, Rotterdam, Netherlands 

242 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cruz LJ, van Dijk T, Vepris O, Li TMWY, Schomann T, Baldazzi F, Kurita R, Nakamura Y, Grosveld F, Philipsen S, Eich C. PLGA-Nanoparticles for Intracellular Delivery of the CRISPR-Complex to Elevate Fetal Globin Expression in Erythroid Cells. Biomaterials. 268: 120580. PMID 33321292 DOI: 10.1016/j.biomaterials.2020.120580  0.48
2020 Papadopoulos P, Kafasi A, De Cuyper IM, Barroca V, Lewandowski D, Kadri Z, Veldthuis M, Berghuis J, Gillemans N, Cuesta CMB, Grosveld FG, van Zwieten R, Philipsen S, Vernet M, Gutiérrez L, et al. Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B. Human Genomics. 14: 39. PMID 33066815 DOI: 10.1186/s40246-020-00283-3  0.48
2020 Miyata M, Gillemans N, Hockman D, Demmers JA, Cheng JF, Hou J, Salminen M, Fisher C, Taylor S, Gibbons RJ, Ganis JJ, Zon LI, Grosveld F, Mulugeta E, Sauka-Spengler T, et al. An evolutionary ancient mechanism for regulation of hemoglobin expression in vertebrate red cells. Blood. PMID 32396940 DOI: 10.1182/Blood.2020004826  0.48
2019 Cantú I, van de Werken HJG, Gillemans N, Stadhouders R, Heshusius S, Maas A, Esteghamat F, Ozgur Z, van IJcken WFJ, Grosveld F, von Lindern M, Philipsen S, van Dijk TB. The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation. Plos One. 14: e0208659. PMID 30921348 DOI: 10.1371/Journal.Pone.0208659  0.64
2016 Breton A, Theodorou A, Aktuna S, Sonzogni L, Darling D, Chan L, Menzel S, van der Spek PJ, Swagemakers SM, Grosveld F, Philipsen S, Thein SL. ASH1L (a histone methyltransferase protein) is a novel candidate globin gene regulator revealed by genetic study of an English family with beta-thalassaemia unlinked to the beta-globin locus. British Journal of Haematology. PMID 27434206 DOI: 10.1111/Bjh.14256  0.48
2015 Stadhouders R, Cico A, Stephen T, Thongjuea S, Kolovos P, Baymaz HI, Yu X, Demmers J, Bezstarosti K, Maas A, Barroca V, Kockx C, Ozgur Z, van Ijcken W, Arcangeli ML, ... ... Grosveld F, et al. Control of developmentally primed erythroid genes by combinatorial co-repressor actions. Nature Communications. 6: 8893. PMID 26593974 DOI: 10.1038/ncomms9893  1
2015 Caputo L, Witzel HR, Kolovos P, Cheedipudi S, Looso M, Mylona A, van IJcken WF, Laugwitz KL, Evans SM, Braun T, Soler E, Grosveld F, Dobreva G. The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors. Cell Stem Cell. 17: 287-99. PMID 26321200 DOI: 10.1016/J.Stem.2015.08.007  1
2015 Papadopoulos P, Gutiérrez L, Demmers J, Scheer E, Pourfarzad F, Papageorgiou DN, Karkoulia E, Strouboulis J, van de Werken HJ, van der Linden R, Vandenberghe P, Dekkers DH, Philipsen S, Grosveld F, Tora L. TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis. Molecular and Cellular Biology. 35: 2103-18. PMID 25870109 DOI: 10.1128/Mcb.01370-14  1
2015 Gu W, Monteiro R, Zuo J, Simões FC, Martella A, Andrieu-Soler C, Grosveld F, Sauka-Spengler T, Patient R. A novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedback. Plos Biology. 13: e1002051. PMID 25665164 DOI: 10.1371/Journal.Pbio.1002051  1
2015 van den Heuvel A, Stadhouders R, Andrieu-Soler C, Grosveld F, Soler E. Long-range gene regulation and novel therapeutic applications. Blood. 125: 1521-5. PMID 25617428 DOI: 10.1182/Blood-2014-11-567925  1
2014 Giraud G, Stadhouders R, Conidi A, Dekkers DH, Huylebroeck D, Demmers JA, Soler E, Grosveld FG. NLS-tagging: an alternative strategy to tag nuclear proteins. Nucleic Acids Research. 42. PMID 25260593 DOI: 10.1093/nar/gku869  1
2014 Kapere Ochieng J, Schilders K, Kool H, Buscop-van Kempen M, Boerema-De Munck A, Grosveld F, Wijnen R, Tibboel D, Rottier RJ. Differentiated type II pneumocytes can be reprogrammed by ectopic Sox2 expression. Plos One. 9: e107248. PMID 25210856 DOI: 10.1371/Journal.Pone.0107248  1
2014 Farahbakhshian E, Verstegen MM, Visser TP, Kheradmandkia S, Geerts D, Arshad S, Riaz N, Grosveld F, van Til NP, Meijerink JP. Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cells. Plos One. 9: e105642. PMID 25170927 DOI: 10.1371/Journal.Pone.0105642  1
2014 van Haren J, Boudeau J, Schmidt S, Basu S, Liu Z, Lammers D, Demmers J, Benhari J, Grosveld F, Debant A, Galjart N. Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension. Current Biology : Cb. 24: 1778-85. PMID 25065758 DOI: 10.1016/J.Cub.2014.06.037  1
2014 Kolovos P, van de Werken HJ, Kepper N, Zuin J, Brouwer RW, Kockx CE, Wendt KS, van IJcken WF, Grosveld F, Knoch TA. Targeted Chromatin Capture (T2C): a novel high resolution high throughput method to detect genomic interactions and regulatory elements. Epigenetics & Chromatin. 7: 10. PMID 25031611 DOI: 10.1186/1756-8935-7-10  1
2014 Soler E, Grosveld F. Targeting epigenetics to speed up repair. Cell Stem Cell. 14: 553-4. PMID 24792110 DOI: 10.1016/J.Stem.2014.04.018  1
2014 Ochieng JK, Schilders K, Kool H, Boerema-De Munck A, Buscop-Van Kempen M, Gontan C, Smits R, Grosveld FG, Wijnen RM, Tibboel D, Rottier RJ. Sox2 regulates the emergence of lung basal cells by directly activating the transcription of Trp63. American Journal of Respiratory Cell and Molecular Biology. 51: 311-22. PMID 24669837 DOI: 10.1165/rcmb.2013-0419OC  1
2014 Stadhouders R, Aktuna S, Thongjuea S, Aghajanirefah A, Pourfarzad F, van Ijcken W, Lenhard B, Rooks H, Best S, Menzel S, Grosveld F, Thein SL, Soler E. HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. The Journal of Clinical Investigation. 124: 1699-710. PMID 24614105 DOI: 10.1182/Blood.V122.21.43.43  1
2014 Stadhouders R, de Bruijn MJ, Rother MB, Yuvaraj S, Ribeiro de Almeida C, Kolovos P, Van Zelm MC, van Ijcken W, Grosveld F, Soler E, Hendriks RW. Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions. Plos Biology. 12: e1001791. PMID 24558349 DOI: 10.1371/Journal.Pbio.1001791  1
2014 Wendt KS, Grosveld FG. Transcription in the context of the 3D nucleus. Current Opinion in Genetics & Development. 25: 62-7. PMID 24534714 DOI: 10.1016/j.gde.2013.11.020  1
2014 Visser M, Kayser M, Grosveld F, Palstra RJ. Genetic variation in regulatory DNA elements: the case of OCA2 transcriptional regulation. Pigment Cell & Melanoma Research. 27: 169-77. PMID 24387780 DOI: 10.1111/Pcmr.12210  1
2014 Zuin J, Dixon JR, van der Reijden MI, Ye Z, Kolovos P, Brouwer RW, van de Corput MP, van de Werken HJ, Knoch TA, van IJcken WF, Grosveld FG, Ren B, Wendt KS. Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 996-1001. PMID 24335803 DOI: 10.1073/Pnas.1317788111  1
2013 Francius C, Harris A, Rucchin V, Hendricks TJ, Stam FJ, Barber M, Kurek D, Grosveld FG, Pierani A, Goulding M, Clotman F. Identification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cord. Plos One. 8: e70325. PMID 23967072 DOI: 10.1371/Journal.Pone.0070325  1
2013 Pourfarzad F, Aghajanirefah A, de Boer E, Ten Have S, Bryn van Dijk T, Kheradmandkia S, Stadhouders R, Thongjuea S, Soler E, Gillemans N, von Lindern M, Demmers J, Philipsen S, Grosveld F. Locus-specific proteomics by TChP: targeted chromatin purification. Cell Reports. 4: 589-600. PMID 23911284 DOI: 10.1016/J.Celrep.2013.07.004  1
2013 Thongjuea S, Stadhouders R, Grosveld FG, Soler E, Lenhard B. r3Cseq: an R/Bioconductor package for the discovery of long-range genomic interactions from chromosome conformation capture and next-generation sequencing data. Nucleic Acids Research. 41: e132. PMID 23671339 DOI: 10.1093/nar/gkt373  1
2013 Ghamari A, van de Corput MP, Thongjuea S, van Cappellen WA, van Ijcken W, van Haren J, Soler E, Eick D, Lenhard B, Grosveld FG. In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes & Development. 27: 767-77. PMID 23592796 DOI: 10.1101/gad.216200.113  1
2013 Papasavva T, van Ijcken WF, Kockx CE, van den Hout MC, Kountouris P, Kythreotis L, Kalogirou E, Grosveld FG, Kleanthous M. Next generation sequencing of SNPs for non-invasive prenatal diagnosis: challenges and feasibility as illustrated by an application to β-thalassaemia. European Journal of Human Genetics : Ejhg. 21: 1403-10. PMID 23572027 DOI: 10.1038/ejhg.2013.47  1
2013 Outchkourov NS, Muiño JM, Kaufmann K, van Ijcken WF, Groot Koerkamp MJ, van Leenen D, de Graaf P, Holstege FC, Grosveld FG, Timmers HT. Balancing of histone H3K4 methylation states by the Kdm5c/SMCX histone demethylase modulates promoter and enhancer function. Cell Reports. 3: 1071-9. PMID 23545502 DOI: 10.1016/j.celrep.2013.02.030  1
2013 Carvalho RH, Hou J, Haberle V, Aerts J, Grosveld F, Lenhard B, Philipsen S. Genomewide DNA methylation analysis identifies novel methylated genes in non-small-cell lung carcinomas. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 562-73. PMID 23524404 DOI: 10.1097/Jto.0B013E3182863Ed2  1
2013 Huang Y, Kapere Ochieng J, Kempen MB, Munck AB, Swagemakers S, van Ijcken W, Grosveld F, Tibboel D, Rottier RJ. Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development. Plos One. 8: e57695. PMID 23451260 DOI: 10.1371/Journal.Pone.0057695  1
2013 Henikoff S, Grosveld F. Epigenetics & chromatin: interactions and processes. Epigenetics & Chromatin. 6: 2. PMID 23442888 DOI: 10.1186/1756-8935-6-2  1
2013 Stadhouders R, Kolovos P, Brouwer R, Zuin J, van den Heuvel A, Kockx C, Palstra RJ, Wendt KS, Grosveld F, van Ijcken W, Soler E. Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions. Nature Protocols. 8: 509-24. PMID 23411633 DOI: 10.1038/Nprot.2013.018  1
2013 Yin H, Pasut A, Soleimani VD, Bentzinger CF, Antoun G, Thorn S, Seale P, Fernando P, van Ijcken W, Grosveld F, Dekemp RA, Boushel R, Harper ME, Rudnicki MA. MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metabolism. 17: 210-24. PMID 23395168 DOI: 10.1016/J.Cmet.2013.01.004  1
2013 Mylona A, Andrieu-Soler C, Thongjuea S, Martella A, Soler E, Jorna R, Hou J, Kockx C, van Ijcken W, Lenhard B, Grosveld F. Genome-wide analysis shows that Ldb1 controls essential hematopoietic genes/pathways in mouse early development and reveals novel players in hematopoiesis. Blood. 121: 2902-13. PMID 23390196 DOI: 10.1182/Blood-2012-11-467654  1
2013 Esteghamat F, Gillemans N, Bilic I, van den Akker E, Cantù I, van Gent T, Klingmüller U, van Lom K, von Lindern M, Grosveld F, Bryn van Dijk T, Busslinger M, Philipsen S. Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood. 121: 2553-62. PMID 23361909 DOI: 10.1182/Blood-2012-06-434530  1
2013 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, et al. Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 77: 70-82. PMID 23312517 DOI: 10.1016/J.Neuron.2012.11.009  1
2013 Price FD, Yin H, Jones A, van Ijcken W, Grosveld F, Rudnicki MA. Canonical Wnt signaling induces a primitive endoderm metastable state in mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 31: 752-64. PMID 23307624 DOI: 10.1002/Stem.1321  1
2013 Pourfarzad F, von Lindern M, Azarkeivan A, Hou J, Kia SK, Esteghamat F, van Ijcken W, Philipsen S, Najmabadi H, Grosveld F. Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity. Haematologica. 98: 696-704. PMID 23100274 DOI: 10.3324/Haematol.2012.074492  1
2012 Papadopoulos P, Gutiérrez L, van der Linden R, Kong-A-San J, Maas A, Drabek D, Patrinos GP, Philipsen S, Grosveld F. A dual reporter mouse model of the human β-globin locus: applications and limitations. Plos One. 7: e51272. PMID 23272095 DOI: 10.1371/Journal.Pone.0051272  1
2012 Drabek K, Gutiérrez L, Vermeij M, Clapes T, Patel SR, Boisset JC, van Haren J, Pereira AL, Liu Z, Akinci U, Nikolic T, van Ijcken W, van den Hout M, Meinders M, Melo C, ... ... Grosveld F, et al. The microtubule plus-end tracking protein CLASP2 is required for hematopoiesis and hematopoietic stem cell maintenance. Cell Reports. 2: 781-8. PMID 23084744 DOI: 10.1016/J.Celrep.2012.08.040  1
2012 Palstra RJ, Grosveld F. Transcription factor binding at enhancers: shaping a genomic regulatory landscape in flux. Frontiers in Genetics. 3: 195. PMID 23060900 DOI: 10.3389/Fgene.2012.00195  1
2012 Borg J, Phylactides M, Bartsakoulia M, Tafrali C, Lederer C, Felice AE, Papachatzopoulou A, Kourakli A, Stavrou EF, Christou S, Hou J, Karkabouna S, Lappa-Manakou C, Ozgur Z, van Ijcken W, ... ... Grosveld FG, et al. KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients. Pharmacogenomics. 13: 1487-500. PMID 23057549 DOI: 10.2217/pgs.12.125  1
2012 Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, ... ... Grosveld FG, et al. The mammalian gene function resource: the International Knockout Mouse Consortium. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 580-6. PMID 22968824 DOI: 10.1007/S00335-012-9422-2  1
2012 Kheradmand Kia S, Verbeek E, Engelen E, Schot R, Poot RA, de Coo IF, Lequin MH, Poulton CJ, Pourfarzad F, Grosveld FG, Brehm A, de Wit MC, Oegema R, Dobyns WB, Verheijen FW, et al. RTTN mutations link primary cilia function to organization of the human cerebral cortex. American Journal of Human Genetics. 91: 533-40. PMID 22939636 DOI: 10.1016/j.ajhg.2012.07.008  1
2012 Fanis P, Gillemans N, Aghajanirefah A, Pourfarzad F, Demmers J, Esteghamat F, Vadlamudi RK, Grosveld F, Philipsen S, van Dijk TB. Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation. Molecular & Cellular Proteomics : McP. 11: 1263-73. PMID 22872859 DOI: 10.1074/Mcp.M112.017194  1
2012 van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, ... Grosveld F, et al. A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Molecular and Cellular Biology. 32: 3814-22. PMID 22801375 DOI: 10.1128/Mcb.05938-11  1
2012 Stadhouders R, van den Heuvel A, Kolovos P, Jorna R, Leslie K, Grosveld F, Soler E. Transcription regulation by distal enhancers: who's in the loop? Transcription. 3: 181-6. PMID 22771987 DOI: 10.4161/trns.20720  1
2012 Soleimani VD, Yin H, Jahani-Asl A, Ming H, Kockx CE, van Ijcken WF, Grosveld F, Rudnicki MA. Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis. Molecular Cell. 47: 457-68. PMID 22771117 DOI: 10.1016/J.Molcel.2012.05.046  1
2012 van de Corput MP, de Boer E, Knoch TA, van Cappellen WA, Quintanilla A, Ferrand L, Grosveld FG. Super-resolution imaging reveals three-dimensional folding dynamics of the β-globin locus upon gene activation. Journal of Cell Science. 125: 4630-9. PMID 22767512 DOI: 10.1242/jcs.108522  1
2012 Carvalho RH, Haberle V, Hou J, van Gent T, Thongjuea S, van Ijcken W, Kockx C, Brouwer R, Rijkers E, Sieuwerts A, Foekens J, van Vroonhoven M, Aerts J, Grosveld F, Lenhard B, et al. Genome-wide DNA methylation profiling of non-small cell lung carcinomas. Epigenetics & Chromatin. 5: 9. PMID 22726460 DOI: 10.1186/1756-8935-5-9  1
2012 Sleutels F, Soochit W, Bartkuhn M, Heath H, Dienstbach S, Bergmaier P, Franke V, Rosa-Garrido M, van de Nobelen S, Caesar L, van der Reijden M, Bryne JC, van Ijcken W, Grootegoed JA, Delgado MD, ... ... Grosveld F, et al. The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner. Epigenetics & Chromatin. 5: 8. PMID 22709888 DOI: 10.1186/1756-8935-5-8  1
2012 Raghoebir L, Bakker ER, Mills JC, Swagemakers S, Kempen MB, Munck AB, Driegen S, Meijer D, Grosveld F, Tibboel D, Smits R, Rottier RJ. SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype. Journal of Molecular Cell Biology. 4: 377-85. PMID 22679103 DOI: 10.1093/Jmcb/Mjs030  1
2012 Soleimani VD, Punch VG, Kawabe Y, Jones AE, Palidwor GA, Porter CJ, Cross JW, Carvajal JJ, Kockx CE, van IJcken WF, Perkins TJ, Rigby PW, Grosveld F, Rudnicki MA. Transcriptional dominance of Pax7 in adult myogenesis is due to high-affinity recognition of homeodomain motifs. Developmental Cell. 22: 1208-20. PMID 22609161 DOI: 10.1016/J.Devcel.2012.03.014  1
2012 Brazão TF, Demmers J, van IJcken W, Strouboulis J, Fornerod M, Romão L, Grosveld FG. A new function of ROD1 in nonsense-mediated mRNA decay. Febs Letters. 586: 1101-10. PMID 22575643 DOI: 10.1016/j.febslet.2012.03.015  1
2012 Adams D, Altucci L, Antonarakis SE, Ballesteros J, Beck S, Bird A, Bock C, Boehm B, Campo E, Caricasole A, Dahl F, Dermitzakis ET, Enver T, Esteller M, Estivill X, ... ... Grosveld F, et al. BLUEPRINT to decode the epigenetic signature written in blood. Nature Biotechnology. 30: 224-6. PMID 22398613 DOI: 10.1038/Nbt.2153  1
2012 Huang Y, Kempen MB, Munck AB, Swagemakers S, Driegen S, Mahavadi P, Meijer D, van Ijcken W, van der Spek P, Grosveld F, Günther A, Tibboel D, Rottier RJ. Hypoxia-inducible factor 2α plays a critical role in the formation of alveoli and surfactant. American Journal of Respiratory Cell and Molecular Biology. 46: 224-32. PMID 22298531 DOI: 10.1165/Rcmb.2011-0024Oc  1
2012 Kolovos P, Knoch TA, Grosveld FG, Cook PR, Papantonis A. Enhancers and silencers: an integrated and simple model for their function. Epigenetics & Chromatin. 5: 1. PMID 22230046 DOI: 10.1186/1756-8935-5-1  1
2012 Stadhouders R, Thongjuea S, Andrieu-Soler C, Palstra RJ, Bryne JC, van den Heuvel A, Stevens M, de Boer E, Kockx C, van der Sloot A, van den Hout M, van Ijcken W, Eick D, Lenhard B, Grosveld F, et al. Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. The Embo Journal. 31: 986-99. PMID 22157820 DOI: 10.1038/Emboj.2011.450  1
2012 Hou J, Lambers M, den Hamer B, den Bakker MA, Hoogsteden HC, Grosveld F, Hegmans J, Aerts J, Philipsen S. Expression profiling-based subtyping identifies novel non-small cell lung cancer subgroups and implicates putative resistance to pemetrexed therapy. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 105-14. PMID 22134068 DOI: 10.1097/JTO.0b013e3182352a45  1
2012 Brouwer RW, van den Hout MC, Grosveld FG, van Ijcken WF. NARWHAL, a primary analysis pipeline for NGS data. Bioinformatics (Oxford, England). 28: 284-5. PMID 22072383 DOI: 10.1093/bioinformatics/btr613  1
2011 Hou J, Lambers L, Hamer BD, Bakker MD, Hoogsteden H, Grosveld F, Hegmans J, Aerts J, Philipsen S. Expression profiling-based subtyping of NSCLC and its putative association with response to chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e21111. PMID 28022822 DOI: 10.1200/jco.2011.29.15_suppl.e21111  0.48
2011 Ribeiro de Almeida C, Stadhouders R, de Bruijn MJ, Bergen IM, Thongjuea S, Lenhard B, van Ijcken W, Grosveld F, Galjart N, Soler E, Hendriks RW. The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus. Immunity. 35: 501-13. PMID 22035845 DOI: 10.1016/J.Immuni.2011.07.014  1
2011 Laventie BJ, Rademaker HJ, Saleh M, de Boer E, Janssens R, Bourcier T, Subilia A, Marcellin L, van Haperen R, Lebbink JH, Chen T, Prévost G, Grosveld F, Drabek D. Heavy chain-only antibodies and tetravalent bispecific antibody neutralizing Staphylococcus aureus leukotoxins. Proceedings of the National Academy of Sciences of the United States of America. 108: 16404-9. PMID 21930905 DOI: 10.1073/Pnas.1102265108  1
2011 Porcu S, Manchinu MF, Marongiu MF, Sogos V, Poddie D, Asunis I, Porcu L, Marini MG, Moi P, Cao A, Grosveld F, Ristaldi MS. Klf1 affects DNase II-alpha expression in the central macrophage of a fetal liver erythroblastic island: a non-cell-autonomous role in definitive erythropoiesis. Molecular and Cellular Biology. 31: 4144-54. PMID 21807894 DOI: 10.1128/Mcb.05532-11  1
2011 Lunardi A, Gaboli M, Giorgio M, Rivi R, Bygrave A, Antoniou M, Drabek D, Dzierzak E, Fagioli M, Salmena L, Botto M, Cordon-Cardo C, Luzzatto L, Pelicci PG, Grosveld F, et al. A Role for PML in Innate Immunity. Genes & Cancer. 2: 10-9. PMID 21779477 DOI: 10.1177/1947601911402682  1
2011 Cui S, Kolodziej KE, Obara N, Amaral-Psarris A, Demmers J, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O. Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells. Molecular and Cellular Biology. 31: 3298-311. PMID 21670149 DOI: 10.1128/MCB.05310-11  1
2011 Jagalur NB, Ghazvini M, Mandemakers W, Driegen S, Maas A, Jones EA, Jaegle M, Grosveld F, Svaren J, Meijer D. Functional dissection of the Oct6 Schwann cell enhancer reveals an essential role for dimeric Sox10 binding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8585-94. PMID 21653862 DOI: 10.1523/Jneurosci.0659-11.2011  1
2011 Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, Demmers J, Rijkers EJ, Bhattacharya S, Philipsen S, Pevny LH, ... Grosveld FG, et al. Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Nature Genetics. 43: 607-11. PMID 21532573 DOI: 10.1038/Ng.825  1
2011 Soler E, Andrieu-Soler C, Boer Ed, Bryne JC, Thongjuea S, Rijkers E, Demmers J, van IJcken W, Grosveld F. A systems approach to analyze transcription factors in mammalian cells. Methods (San Diego, Calif.). 53: 151-62. PMID 20705139 DOI: 10.1016/J.Ymeth.2010.08.002  1
2010 van de Nobelen S, Rosa-Garrido M, Leers J, Heath H, Soochit W, Joosen L, Jonkers I, Demmers J, van der Reijden M, Torrano V, Grosveld F, Delgado MD, Renkawitz R, Galjart N, Sleutels F. CTCF regulates the local epigenetic state of ribosomal DNA repeats. Epigenetics & Chromatin. 3: 19. PMID 21059229 DOI: 10.1186/1756-8935-3-19  1
2010 Tsarovina K, Reiff T, Stubbusch J, Kurek D, Grosveld FG, Parlato R, Schütz G, Rohrer H. The Gata3 transcription factor is required for the survival of embryonic and adult sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10833-43. PMID 20702712 DOI: 10.1523/Jneurosci.0175-10.2010  1
2010 van Dijk TB, Gillemans N, Pourfarzad F, van Lom K, von Lindern M, Grosveld F, Philipsen S. Fetal globin expression is regulated by Friend of Prmt1. Blood. 116: 4349-52. PMID 20688955 DOI: 10.1182/Blood-2010-03-274399  1
2010 Borg J, Papadopoulos P, Georgitsi M, Gutiérrez L, Grech G, Fanis P, Phylactides M, Verkerk AJ, van der Spek PJ, Scerri CA, Cassar W, Galdies R, van Ijcken W, Ozgür Z, Gillemans N, ... ... Grosveld FG, et al. Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin. Nature Genetics. 42: 801-5. PMID 20676099 DOI: 10.1038/ng.630  1
2010 Bezstarosti K, Ghamari A, Grosveld FG, Demmers JA. Differential proteomics based on 18O labeling to determine the cyclin dependent kinase 9 interactome. Journal of Proteome Research. 9: 4464-75. PMID 20593818 DOI: 10.1021/pr100217d  1
2010 Kepper N, Ettig R, Dickmann F, Stehr R, Grosveld FG, Wedemann G, Knoch TA. Parallel high-performance grid computing: capabilities and opportunities of a novel demanding service and business class allowing highest resource efficiency. Studies in Health Technology and Informatics. 159: 264-71. PMID 20543448 DOI: 10.7490/F1000Research.1110613.1  1
2010 Kepper N, Schmitt E, Lesnussa M, Weiland Y, Eussen HB, Grosveld FG, Hausmann M, Knoch TA. Visualization, analysis, and design of COMBO-FISH probes in the grid-based GLOBE 3D genome platform. Studies in Health Technology and Informatics. 159: 171-80. PMID 20543436 DOI: 10.3233/978-1-60750-583-9-171  1
2010 Grigorieva IV, Mirczuk S, Gaynor KU, Nesbit MA, Grigorieva EF, Wei Q, Ali A, Fairclough RJ, Stacey JM, Stechman MJ, Mihai R, Kurek D, Fraser WD, Hough T, Condie BG, ... ... Grosveld F, et al. Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. The Journal of Clinical Investigation. 120: 2144-55. PMID 20484821 DOI: 10.1172/Jci42021  1
2010 Stepanova T, Smal I, van Haren J, Akinci U, Liu Z, Miedema M, Limpens R, van Ham M, van der Reijden M, Poot R, Grosveld F, Mommaas M, Meijering E, Galjart N. History-dependent catastrophes regulate axonal microtubule behavior. Current Biology : Cb. 20: 1023-8. PMID 20471267 DOI: 10.1016/J.Cub.2010.04.024  1
2010 Hou J, Aerts J, den Hamer B, van Ijcken W, den Bakker M, Riegman P, van der Leest C, van der Spek P, Foekens JA, Hoogsteden HC, Grosveld F, Philipsen S. Gene expression-based classification of non-small cell lung carcinomas and survival prediction. Plos One. 5: e10312. PMID 20421987 DOI: 10.1371/journal.pone.0010312  1
2010 Soler E, Andrieu-Soler C, de Boer E, Bryne JC, Thongjuea S, Stadhouders R, Palstra RJ, Stevens M, Kockx C, van Ijcken W, Hou J, Steinhoff C, Rijkers E, Lenhard B, Grosveld F. The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation. Genes & Development. 24: 277-89. PMID 20123907 DOI: 10.1101/Gad.551810  1
2010 de Wit T, Dekker S, Maas A, Breedveld G, Knoch TA, Langeveld A, Szumska D, Craig R, Bhattacharya S, Grosveld F, Drabek D. Tagged mutagenesis by efficient Minos-based germ line transposition. Molecular and Cellular Biology. 30: 68-77. PMID 19884347 DOI: 10.1128/Mcb.00913-09  1
2010 van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S. Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases. Molecular and Cellular Biology. 30: 260-72. PMID 19858291 DOI: 10.1128/Mcb.00645-09  1
2010 Knoch TA, Baumgärtner V, Grosveld FG, Egger K. Approaching the internalization challenge of grid technologies into e-society by e-human "grid" ecology Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6296: 116-128. DOI: 10.1007/978-3-642-15681-6_9  1
2010 Soler E, Andrieu-Soler C, De Boer E, Bryne JC, Thongjuea S, Stadhouders R, Palstra RJ, Stevens M, Kockx C, Van Ijcken W, Hou J, Steinhoff C, Rijkers E, Lenhard B, Grosveld F. The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation (Genes & Development (2010) 24, (277-289)) Genes and Development. 24: 623.  1
2009 Jonkers I, Barakat TS, Achame EM, Monkhorst K, Kenter A, Rentmeester E, Grosveld F, Grootegoed JA, Gribnau J. RNF12 is an X-Encoded dose-dependent activator of X chromosome inactivation. Cell. 139: 999-1011. PMID 19945382 DOI: 10.1016/J.Cell.2009.10.034  1
2009 Simonis M, Klous P, Homminga I, Galjaard RJ, Rijkers EJ, Grosveld F, Meijerink JP, de Laat W. High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology. Nature Methods. 6: 837-42. PMID 19820713 DOI: 10.1038/Nmeth.1391  1
2009 Estrada K, Abuseiris A, Grosveld FG, Uitterlinden AG, Knoch TA, Rivadeneira F. GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data. Bioinformatics (Oxford, England). 25: 2750-2. PMID 19700477 DOI: 10.1093/bioinformatics/btp497  1
2009 Lederer CW, Basak AN, Aydinok Y, Christou S, El-Beshlawy A, Eleftheriou A, Fattoum S, Felice AE, Fibach E, Galanello R, Gambari R, Gavrila L, Giordano PC, Grosveld F, Hassapopoulou H, et al. An electronic infrastructure for research and treatment of the thalassemias and other hemoglobinopathies: the Euro-mediterranean ITHANET project. Hemoglobin. 33: 163-76. PMID 19657830 DOI: 10.1080/03630260903089177  1
2009 Knoch TA, Baumgärtner V, de Zeeuw LV, Grosveld FG, Egger K. e-Human Grid Ecology - understanding and approaching the inverse tragedy of the commons in the e-Grid society. Studies in Health Technology and Informatics. 147: 269-76. PMID 19593066 DOI: 10.3233/978-1-60750-027-8-269  1
2009 Knoch TA, Lesnussa M, Kepper N, Eussen HB, Grosveld FG. The GLOBE 3D Genome Platform - towards a novel system-biological paper tool to integrate the huge complexity of genome organization and function. Studies in Health Technology and Informatics. 147: 105-16. PMID 19593049 DOI: 10.3233/978-1-60750-027-8-105  1
2009 Knoch TA, Göker M, Lohner R, Abuseiris A, Grosveld FG. Fine-structured multi-scaling long-range correlations in completely sequenced genomes--features, origin, and classification. European Biophysics Journal : Ebj. 38: 757-79. PMID 19533117 DOI: 10.1007/s00249-009-0489-y  1
2009 van Haperen R, Samyn H, van Gent T, Zonneveld AJ, Moerland M, Grosveld F, Jansen H, Dallinga-Thie GM, van Tol A, de Crom R. Novel roles of hepatic lipase and phospholipid transfer protein in VLDL as well as HDL metabolism. Biochimica Et Biophysica Acta. 1791: 1031-6. PMID 19524061 DOI: 10.1016/j.bbalip.2009.06.001  1
2009 Monkhorst K, de Hoon B, Jonkers I, Mulugeta Achame E, Monkhorst W, Hoogerbrugge J, Rentmeester E, Westerhoff HV, Grosveld F, Grootegoed JA, Gribnau J. The probability to initiate X chromosome inactivation is determined by the X to autosomal ratio and X chromosome specific allelic properties. Plos One. 4: e5616. PMID 19440388 DOI: 10.1371/Journal.Pone.0005616  1
2009 van Haren J, Draegestein K, Keijzer N, Abrahams JP, Grosveld F, Peeters PJ, Moechars D, Galjart N. Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motility and the Cytoskeleton. 66: 824-38. PMID 19396870 DOI: 10.1002/Cm.20370  1
2009 Gontan C, Güttler T, Engelen E, Demmers J, Fornerod M, Grosveld FG, Tibboel D, Görlich D, Poot RA, Rottier RJ. Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors. The Journal of Cell Biology. 185: 27-34. PMID 19349578 DOI: 10.1083/jcb.200810106  1
2009 Kolodziej KE, Pourfarzad F, de Boer E, Krpic S, Grosveld F, Strouboulis J. Optimal use of tandem biotin and V5 tags in ChIP assays. Bmc Molecular Biology. 10: 6. PMID 19196479 DOI: 10.1186/1471-2199-10-6  1
2009 Ribeiro de Almeida C, Heath H, Krpic S, Dingjan GM, van Hamburg JP, Bergen I, van de Nobelen S, Sleutels F, Grosveld F, Galjart N, Hendriks RW. Critical role for the transcription regulator CCCTC-binding factor in the control of Th2 cytokine expression. Journal of Immunology (Baltimore, Md. : 1950). 182: 999-1010. PMID 19124743 DOI: 10.4049/Jimmunol.182.2.999  1
2009 Samyn H, Moerland M, van Gent T, van Haperen R, Grosveld F, van Tol A, de Crom R. Elevation of systemic PLTP, but not macrophage-PLTP, impairs macrophage reverse cholesterol transport in transgenic mice. Atherosclerosis. 204: 429-34. PMID 19100548 DOI: 10.1016/j.atherosclerosis.2008.10.020  1
2008 Heath H, Ribeiro de Almeida C, Sleutels F, Dingjan G, van de Nobelen S, Jonkers I, Ling KW, Gribnau J, Renkawitz R, Grosveld F, Hendriks RW, Galjart N. CTCF regulates cell cycle progression of alphabeta T cells in the thymus. The Embo Journal. 27: 2839-50. PMID 18923423 DOI: 10.1038/Emboj.2008.214  1
2008 Samyn H, Moerland M, van Gent T, van Haperen R, Metso J, Grosveld F, Jauhiainen M, van Tol A, de Crom R. Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study. Journal of Lipid Research. 49: 2504-12. PMID 18711210 DOI: 10.1194/Jlr.M800080-Jlr200  1
2008 Jonkers I, Monkhorst K, Rentmeester E, Grootegoed JA, Grosveld F, Gribnau J. Xist RNA is confined to the nuclear territory of the silenced X chromosome throughout the cell cycle. Molecular and Cellular Biology. 28: 5583-94. PMID 18625719 DOI: 10.1128/Mcb.02269-07  1
2008 van Haperen R, Samyn H, Moerland M, van Gent T, Peeters M, Grosveld F, van Tol A, de Crom R. Elevated expression of phospholipid transfer protein in bone marrow derived cells causes atherosclerosis. Plos One. 3: e2255. PMID 18509527 DOI: 10.1371/Journal.Pone.0002255  1
2008 Jhunjhunwala S, van Zelm MC, Peak MM, Cutchin S, Riblet R, van Dongen JJ, Grosveld FG, Knoch TA, Murre C. The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. Cell. 133: 265-79. PMID 18423198 DOI: 10.1016/J.Cell.2008.03.024  1
2008 Moerland M, Samyn H, van Gent T, van Haperen R, Dallinga-Thie G, Grosveld F, van Tol A, de Crom R. Acute elevation of plasma PLTP activity strongly increases pre-existing atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1277-82. PMID 18421000 DOI: 10.1161/Atvbaha.108.165084  1
2008 Gontan C, de Munck A, Vermeij M, Grosveld F, Tibboel D, Rottier R. Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Developmental Biology. 317: 296-309. PMID 18374910 DOI: 10.1016/J.Ydbio.2008.02.035  1
2008 Dragestein KA, van Cappellen WA, van Haren J, Tsibidis GD, Akhmanova A, Knoch TA, Grosveld F, Galjart N. Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends. The Journal of Cell Biology. 180: 729-37. PMID 18283108 DOI: 10.1083/Jcb.200707203  1
2008 de Laat W, Klous P, Kooren J, Noordermeer D, Palstra RJ, Simonis M, Splinter E, Grosveld F. Three-dimensional organization of gene expression in erythroid cells. Current Topics in Developmental Biology. 82: 117-39. PMID 18282519 DOI: 10.1016/S0070-2153(07)00005-1  1
2008 Palstra RJ, de Laat W, Grosveld F. Beta-globin regulation and long-range interactions. Advances in Genetics. 61: 107-42. PMID 18282504 DOI: 10.1016/S0065-2660(07)00004-1  1
2008 Patrinos GP, Grosveld FG. Pharmacogenomics and therapeutics of hemoglobinopathies. Hemoglobin. 32: 229-36. PMID 18275000 DOI: 10.1080/03630260701680367  1
2008 Monkhorst K, Jonkers I, Rentmeester E, Grosveld F, Gribnau J. X inactivation counting and choice is a stochastic process: evidence for involvement of an X-linked activator. Cell. 132: 410-21. PMID 18267073 DOI: 10.1016/J.Cell.2007.12.036  1
2007 Grosveld FG, Duboule D. Differentiation and gene regulation. Current Opinion in Genetics & Development. 17: 369-72. PMID 17959371 DOI: 10.1016/J.Gde.2007.10.001  1
2007 van Loo PF, Mahtab EA, Wisse LJ, Hou J, Grosveld F, Suske G, Philipsen S, Gittenberger-de Groot AC. Transcription factor Sp3 knockout mice display serious cardiac malformations. Molecular and Cellular Biology. 27: 8571-82. PMID 17923686 DOI: 10.1128/Mcb.01350-07  1
2007 Katsantoni EZ, Anghelescu NE, Rottier R, Moerland M, Antoniou M, de Crom R, Grosveld F, Strouboulis J. Ubiquitous expression of the rtTA2S-M2 inducible system in transgenic mice driven by the human hnRNPA2B1/CBX3 CpG island. Bmc Developmental Biology. 7: 108. PMID 17900353 DOI: 10.1186/1471-213X-7-108  1
2007 de Laat W, Grosveld F. Inter-chromosomal gene regulation in the mammalian cell nucleus. Current Opinion in Genetics & Development. 17: 456-64. PMID 17884460 DOI: 10.1016/J.Gde.2007.07.009  1
2007 Moerland M, Samyn H, van Gent T, Jauhiainen M, Metso J, van Haperen R, Grosveld F, van Tol A, de Crom R. Atherogenic, enlarged, and dysfunctional HDL in human PLTP/apoA-I double transgenic mice. Journal of Lipid Research. 48: 2622-31. PMID 17761633 DOI: 10.1194/Jlr.M700020-Jlr200  1
2007 Grigoriev I, Splinter D, Keijzer N, Wulf PS, Demmers J, Ohtsuka T, Modesti M, Maly IV, Grosveld F, Hoogenraad CC, Akhmanova A. Rab6 regulates transport and targeting of exocytotic carriers. Developmental Cell. 13: 305-14. PMID 17681140 DOI: 10.1016/J.Devcel.2007.06.010  1
2007 Papachatzopoulou A, Kaimakis P, Pourfarzad F, Menounos PG, Evangelakou P, Kollia P, Grosveld FG, Patrinos GP. Increased gamma-globin gene expression in beta-thalassemia intermedia patients correlates with a mutation in 3'HS1. American Journal of Hematology. 82: 1005-9. PMID 17654503 DOI: 10.1002/ajh.20979  1
2007 Gutiérrez L, Nikolic T, van Dijk TB, Hammad H, Vos N, Willart M, Grosveld F, Philipsen S, Lambrecht BN. Gata1 regulates dendritic-cell development and survival. Blood. 110: 1933-41. PMID 17505015 DOI: 10.1182/Blood-2006-09-048322  1
2007 Moerland M, Anghelescu N, Samyn H, van Haperen R, van Gent T, Strouboulis J, van Tol A, Grosveld F, de Crom R. Inducible expression of phospholipid transfer protein (PLTP) in transgenic mice: acute effects of PLTP on lipoprotein metabolism. Transgenic Research. 16: 503-13. PMID 17437182 DOI: 10.1007/s11248-007-9094-y  1
2007 Kooren J, Palstra RJ, Klous P, Splinter E, von Lindern M, Grosveld F, de Laat W. Beta-globin active chromatin Hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice. The Journal of Biological Chemistry. 282: 16544-52. PMID 17428799 DOI: 10.1074/Jbc.M701159200  1
2007 Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindern M, Ohneda K, Grosveld F, Yamamoto M, Philipsen S. Dynamic regulation of Gata factor levels is more important than their identity. Blood. 109: 5481-90. PMID 17327407 DOI: 10.1182/Blood-2006-11-060491  1
2007 Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, Hartley L, Robb L, Grosveld FG, van der Wees J, Lindeman GJ, Visvader JE. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nature Cell Biology. 9: 201-9. PMID 17187062 DOI: 10.1038/ncb1530  1
2007 Kurek D, Garinis GA, van Doorninck JH, van der Wees J, Grosveld FG. Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles. Development (Cambridge, England). 134: 261-72. PMID 17151017 DOI: 10.1242/dev.02721  1
2007 Markaki M, Drabek D, Livadaras I, Craig RK, Grosveld F, Savakis C. Stable expression of human growth hormone over 50 generations in transgenic insect larvae. Transgenic Research. 16: 99-107. PMID 17103025 DOI: 10.1007/S11248-006-9032-4  1
2006 Drabek K, van Ham M, Stepanova T, Draegestein K, van Horssen R, Sayas CL, Akhmanova A, Ten Hagen T, Smits R, Fodde R, Grosveld F, Galjart N. Role of CLASP2 in microtubule stabilization and the regulation of persistent motility. Current Biology : Cb. 16: 2259-64. PMID 17113391 DOI: 10.1016/J.Cub.2006.09.065  1
2006 Meier N, Krpic S, Rodriguez P, Strouboulis J, Monti M, Krijgsveld J, Gering M, Patient R, Hostert A, Grosveld F. Novel binding partners of Ldb1 are required for haematopoietic development. Development (Cambridge, England). 133: 4913-23. PMID 17108004 DOI: 10.1242/Dev.02656  1
2006 Janssens R, Dekker S, Hendriks RW, Panayotou G, van Remoortere A, San JK, Grosveld F, Drabek D. Generation of heavy-chain-only antibodies in mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 15130-5. PMID 17015837 DOI: 10.1073/Pnas.0601108103  1
2006 Splinter E, Heath H, Kooren J, Palstra RJ, Klous P, Grosveld F, Galjart N, de Laat W. CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes & Development. 20: 2349-54. PMID 16951251 DOI: 10.1016/J.Bcmd.2006.10.131  1
2006 Rodriguez P, Braun H, Kolodziej KE, de Boer E, Campbell J, Bonte E, Grosveld F, Philipsen S, Strouboulis J. Isolation of transcription factor complexes by in vivo biotinylation tagging and direct binding to streptavidin beads. Methods in Molecular Biology (Clifton, N.J.). 338: 305-23. PMID 16888367 DOI: 10.1385/1-59745-097-9:305  1
2006 Lansbergen G, Grigoriev I, Mimori-Kiyosue Y, Ohtsuka T, Higa S, Kitajima I, Demmers J, Galjart N, Houtsmuller AB, Grosveld F, Akhmanova A. CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta. Developmental Cell. 11: 21-32. PMID 16824950 DOI: 10.1016/J.Devcel.2006.05.012  1
2006 Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJ, Krams R, de Crom R. Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation. 113: 2744-53. PMID 16754802 DOI: 10.1161/Circulationaha.105.590018  1
2006 Tam JL, Triantaphyllopoulos K, Todd H, Raguz S, de Wit T, Morgan JE, Partridge TA, Makrinou E, Grosveld F, Antoniou M. The human desmin locus: gene organization and LCR-mediated transcriptional control. Genomics. 87: 733-46. PMID 16545539 DOI: 10.1016/J.Ygeno.2006.01.009  1
2006 Horsman S, Moorhouse MJ, de Jager VC, van der Spek P, Grosveld F, Strouboulis J, Katsantoni EZ. TF Target Mapper: a BLAST search tool for the identification of Transcription Factor target genes. Bmc Bioinformatics. 7: 120. PMID 16524462 DOI: 10.1186/1471-2105-7-120  1
2006 van der Wegen P, Louwen R, Imam AM, Buijs-Offerman RM, Sinaasappel M, Grosveld F, Scholte BJ. Successful treatment of UGT1A1 deficiency in a rat model of Crigler-Najjar disease by intravenous administration of a liver-specific lentiviral vector. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 374-81. PMID 16337205 DOI: 10.1016/J.Ymthe.2005.09.022  1
2006 Cheng C, Tempel D, Van Der Baan A, Krams R, Daemen MJAP, Van Haperen R, Grosveld F, De Crom R. Response to letter regarding article, "atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress" [2] Circulation. 114: e615. DOI: 10.1161/Circulationaha.106.658302  1
2005 Grosveld F, Rodriguez P, Meier N, Krpic S, Pourfarzad F, Papadopoulos P, Kolodziej K, Patrinos GP, Hostert A, Strouboulis J. Isolation and characterization of hematopoietic transcription factor complexes by in vivo biotinylation tagging and mass spectrometry. Annals of the New York Academy of Sciences. 1054: 55-67. PMID 16339652 DOI: 10.1196/annals.1345.008  1
2005 Akhmanova A, Mausset-Bonnefont AL, van Cappellen W, Keijzer N, Hoogenraad CC, Stepanova T, Drabek K, van der Wees J, Mommaas M, Onderwater J, van der Meulen H, Tanenbaum ME, Medema RH, Hoogerbrugge J, Vreeburg J, ... ... Grosveld F, et al. The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes & Development. 19: 2501-15. PMID 16230537 DOI: 10.1101/Gad.344505  1
2005 Gutiérrez L, Lindeboom F, Ferreira R, Drissen R, Grosveld F, Whyatt D, Philipsen S. A hanging drop culture method to study terminal erythroid differentiation. Experimental Hematology. 33: 1083-91. PMID 16219530 DOI: 10.1016/j.exphem.2005.06.014  1
2005 Driegen S, Ferreira R, van Zon A, Strouboulis J, Jaegle M, Grosveld F, Philipsen S, Meijer D. A generic tool for biotinylation of tagged proteins in transgenic mice. Transgenic Research. 14: 477-82. PMID 16201414 DOI: 10.1007/S11248-005-7220-2  1
2005 Komarova Y, Lansbergen G, Galjart N, Grosveld F, Borisy GG, Akhmanova A. EB1 and EB3 control CLIP dissociation from the ends of growing microtubules. Molecular Biology of the Cell. 16: 5334-45. PMID 16148041 DOI: 10.1091/Mbc.E05-07-0614  1
2005 Drissen R, von Lindern M, Kolbus A, Driegen S, Steinlein P, Beug H, Grosveld F, Philipsen S. The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Molecular and Cellular Biology. 25: 5205-14. PMID 15923635 DOI: 10.1128/Mcb.25.12.5205-5214.2005  1
2005 Rodriguez P, Bonte E, Krijgsveld J, Kolodziej KE, Guyot B, Heck AJ, Vyas P, de Boer E, Grosveld F, Strouboulis J. GATA-1 forms distinct activating and repressive complexes in erythroid cells. The Embo Journal. 24: 2354-66. PMID 15920471 DOI: 10.1038/Sj.Emboj.7600702  1
2005 Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, Sasaki H, Matsui C, Severin F, Galjart N, Grosveld F, Vorobjev I, Tsukita S, Akhmanova A. CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex. The Journal of Cell Biology. 168: 141-53. PMID 15631994 DOI: 10.1083/Jcb.200405094  1
2005 Parera MC, van Dooren M, van Kempen M, de Krijger R, Grosveld F, Tibboel D, Rottier R. Distal angiogenesis: a new concept for lung vascular morphogenesis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L141-9. PMID 15377499 DOI: 10.1152/Ajplung.00148.2004  1
2004 Drissen R, Palstra RJ, Gillemans N, Splinter E, Grosveld F, Philipsen S, de Laat W. The active spatial organization of the beta-globin locus requires the transcription factor EKLF. Genes & Development. 18: 2485-90. PMID 15489291 DOI: 10.1101/Gad.317004  1
2004 Lansbergen G, Komarova Y, Modesti M, Wyman C, Hoogenraad CC, Goodson HV, Lemaitre RP, Drechsel DN, van Munster E, Gadella TW, Grosveld F, Galjart N, Borisy GG, Akhmanova A. Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization. The Journal of Cell Biology. 166: 1003-14. PMID 15381688 DOI: 10.1083/Jcb.200402082  1
2004 Darbas A, Jaegle M, Walbeehm E, van den Burg H, Driegen S, Broos L, Uyl M, Visser P, Grosveld F, Meijer D. Cell autonomy of the mouse claw paw mutation. Developmental Biology. 272: 470-82. PMID 15282162 DOI: 10.1016/j.ydbio.2004.05.017  1
2004 van der Wees J, van Looij MA, de Ruiter MM, Elias H, van der Burg H, Liem SS, Kurek D, Engel JD, Karis A, van Zanten BG, de Zeeuw CI, Grosveld FG, van Doorninck JH. Hearing loss following Gata3 haploinsufficiency is caused by cochlear disorder. Neurobiology of Disease. 16: 169-78. PMID 15207274 DOI: 10.1016/j.nbd.2004.02.004  1
2004 Patrinos GP, de Krom M, de Boer E, Langeveld A, Imam AM, Strouboulis J, de Laat W, Grosveld FG. Multiple interactions between regulatory regions are required to stabilize an active chromatin hub. Genes & Development. 18: 1495-509. PMID 15198986 DOI: 10.1101/gad.289704  1
2004 Gutiérrez L, Lindeboom F, Langeveld A, Grosveld F, Philipsen S, Whyatt D. Homotypic signalling regulates Gata1 activity in the erythroblastic island. Development (Cambridge, England). 131: 3183-93. PMID 15175249 DOI: 10.1242/Dev.01198  1
2004 Katsantoni EZ, de Krom M, Kong-a-San J, Imam AM, Grosveld F, Anagnou NP, Strouboulis J. An embryonic-specific repressor element located 3' to the Agamma-globin gene influences transcription of the human beta-globin locus in transgenic mice. Experimental Hematology. 32: 224-33. PMID 15102485 DOI: 10.1016/J.Exphem.2003.11.001  1
2004 Splinter E, Grosveld F, de Laat W. 3C technology: analyzing the spatial organization of genomic loci in vivo. Methods in Enzymology. 375: 493-507. PMID 14870685 DOI: 10.1016/S0076-6879(03)75030-7  1
2003 Samson SI, Richard O, Tavian M, Ranson T, Vosshenrich CA, Colucci F, Buer J, Grosveld F, Godin I, Di Santo JP. GATA-3 promotes maturation, IFN-gamma production, and liver-specific homing of NK cells. Immunity. 19: 701-11. PMID 14614857 DOI: 10.1016/S1074-7613(03)00294-2  1
2003 Hoogenraad CC, Wulf P, Schiefermeier N, Stepanova T, Galjart N, Small JV, Grosveld F, de Zeeuw CI, Akhmanova A. Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. The Embo Journal. 22: 6004-15. PMID 14609947 DOI: 10.1093/Emboj/Cdg592  1
2003 Dekker S, Toussaint W, Panayotou G, de Wit T, Visser P, Grosveld F, Drabek D. Intracellularly expressed single-domain antibody against p15 matrix protein prevents the production of porcine retroviruses. Journal of Virology. 77: 12132-9. PMID 14581550 DOI: 10.1128/Jvi.77.22.12132-12139.2003  1
2003 Haley JD, Smith DE, Schwedes J, Brennan R, Pearce C, Moore C, Wang F, Petti F, Grosveld F, Jane SM, Noguchi CT, Schechter AN. Identification and characterization of mechanistically distinct inducers of gamma-globin transcription. Biochemical Pharmacology. 66: 1755-68. PMID 14563486 DOI: 10.1016/S0006-2952(03)00542-2  1
2003 Palstra RJ, Tolhuis B, Splinter E, Nijmeijer R, Grosveld F, de Laat W. The beta-globin nuclear compartment in development and erythroid differentiation. Nature Genetics. 35: 190-4. PMID 14517543 DOI: 10.1038/Ng1244  1
2003 de Laat W, Grosveld F. Spatial organization of gene expression: the active chromatin hub. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 11: 447-59. PMID 12971721 DOI: 10.1023/A:1024922626726  1
2003 Lindeboom F, Gillemans N, Karis A, Jaegle M, Meijer D, Grosveld F, Philipsen S. A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse. Nucleic Acids Research. 31: 5405-12. PMID 12954777 DOI: 10.1093/Nar/Gkg723  1
2003 Wai AW, Gillemans N, Raguz-Bolognesi S, Pruzina S, Zafarana G, Meijer D, Philipsen S, Grosveld F. HS5 of the human beta-globin locus control region: a developmental stage-specific border in erythroid cells. The Embo Journal. 22: 4489-500. PMID 12941700 DOI: 10.1093/Emboj/Cdg437  1
2003 Bottardi S, Aumont A, Grosveld F, Milot E. Developmental stage-specific epigenetic control of human beta-globin gene expression is potentiated in hematopoietic progenitor cells prior to their transcriptional activation. Blood. 102: 3989-97. PMID 12920025 DOI: 10.1182/Blood-2003-05-1540  1
2003 Katsantoni EZ, Langeveld A, Wai AW, Drabek D, Grosveld F, Anagnou NP, Strouboulis J. Persistent gamma-globin expression in adult transgenic mice is mediated by HPFH-2, HPFH-3, and HPFH-6 breakpoint sequences. Blood. 102: 3412-9. PMID 12855570 DOI: 10.1182/Blood-2003-05-1681  1
2003 de Boer E, Rodriguez P, Bonte E, Krijgsveld J, Katsantoni E, Heck A, Grosveld F, Strouboulis J. Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 7480-5. PMID 12802011 DOI: 10.1073/Pnas.1332608100  1
2003 Jaegle M, Ghazvini M, Mandemakers W, Piirsoo M, Driegen S, Levavasseur F, Raghoenath S, Grosveld F, Meijer D. The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes & Development. 17: 1380-91. PMID 12782656 DOI: 10.1101/Gad.258203  1
2003 Stepanova T, Slemmer J, Hoogenraad CC, Lansbergen G, Dortland B, De Zeeuw CI, Grosveld F, van Cappellen G, Akhmanova A, Galjart N. Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2655-64. PMID 12684451 DOI: 10.1523/Jneurosci.23-07-02655.2003  1
2003 Van Loo PF, Bouwman P, Ling KW, Middendorp S, Suske G, Grosveld F, Dzierzak E, Philipsen S, Hendriks RW. Impaired hematopoiesis in mice lacking the transcription factor Sp3. Blood. 102: 858-66. PMID 12676787 DOI: 10.1182/Blood-2002-06-1848  1
2003 Drabek D, Zagoraiou L, deWit T, Langeveld A, Roumpaki C, Mamalaki C, Savakis C, Grosveld F. Transposition of the Drosophila hydei Minos transposon in the mouse germ line. Genomics. 81: 108-11. PMID 12620388 DOI: 10.1016/S0888-7543(02)00030-7  1
2003 Gillemans N, McMorrow T, Tewari R, Wai AW, Burgtorf C, Drabek D, Ventress N, Langeveld A, Higgs D, Tan-Un K, Grosveld F, Philipsen S. Functional and comparative analysis of globin loci in pufferfish and humans. Blood. 101: 2842-9. PMID 12517812 DOI: 10.1182/Blood-2002-09-2850  1
2002 Tolhuis B, Palstra RJ, Splinter E, Grosveld F, de Laat W. Looping and interaction between hypersensitive sites in the active beta-globin locus. Molecular Cell. 10: 1453-65. PMID 12504019 DOI: 10.1016/S1097-2765(02)00781-5  1
2002 Matanis T, Akhmanova A, Wulf P, Del Nery E, Weide T, Stepanova T, Galjart N, Grosveld F, Goud B, De Zeeuw CI, Barnekow A, Hoogenraad CC. Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nature Cell Biology. 4: 986-92. PMID 12447383 DOI: 10.1038/Ncb891  1
2002 van Haperen R, van Tol A, van Gent T, Scheek L, Visser P, van der Kamp A, Grosveld F, de Crom R. Increased risk of atherosclerosis by elevated plasma levels of phospholipid transfer protein. The Journal of Biological Chemistry. 277: 48938-43. PMID 12372822 DOI: 10.1074/Jbc.M209128200  1
2002 van Haperen R, de Waard M, van Deel E, Mees B, Kutryk M, van Aken T, Hamming J, Grosveld F, Duncker DJ, de Crom R. Reduction of blood pressure, plasma cholesterol, and atherosclerosis by elevated endothelial nitric oxide. The Journal of Biological Chemistry. 277: 48803-7. PMID 12364322 DOI: 10.1074/Jbc.M209477200  1
2002 Ghazvini M, Mandemakers W, Jaegle M, Piirsoo M, Driegen S, Koutsourakis M, Smit X, Grosveld F, Meijer D. A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration. The Embo Journal. 21: 4612-20. PMID 12198163 DOI: 10.1093/Emboj/Cdf475  1
2002 Hoogenraad CC, Koekkoek B, Akhmanova A, Krugers H, Dortland B, Miedema M, van Alphen A, Kistler WM, Jaegle M, Koutsourakis M, Van Camp N, Verhoye M, van der Linden A, Kaverina I, Grosveld F, et al. Targeted mutation of Cyln2 in the Williams syndrome critical region links CLIP-115 haploinsufficiency to neurodevelopmental abnormalities in mice. Nature Genetics. 32: 116-27. PMID 12195424 DOI: 10.1038/Ng954  1
2002 de Wit T, Grosveld F, Drabek D. The tomato RNA-directed RNA polymerase has no effect on gene silencing by RNA interference in transgenic mice. Transgenic Research. 11: 305-10. PMID 12113462 DOI: 10.1023/A:1015687008357  1
2002 de Krom M, van de Corput M, von Lindern M, Grosveld F, Strouboulis J. Stochastic patterns in globin gene expression are established prior to transcriptional activation and are clonally inherited. Molecular Cell. 9: 1319-26. PMID 12086628 DOI: 10.1016/S1097-2765(02)00558-0  1
2002 Chow CM, Athanassiadou A, Raguz S, Psiouri L, Harland L, Malik M, Aitken MA, Grosveld F, Antoniou M. LCR-mediated, long-term tissue-specific gene expression within replicating episomal plasmid and cosmid vectors. Gene Therapy. 9: 327-36. PMID 11938452 DOI: 10.1038/Sj.Gt.3301654  1
2002 Whyatt D, Grosveld F. Cell-nonautonomous function of the retinoblastoma tumour suppressor protein: new interpretations of old phenotypes. Embo Reports. 3: 130-5. PMID 11839697 DOI: 10.1093/Embo-Reports/Kvf033  1
2001 Simon I, Tenzen T, Mostoslavsky R, Fibach E, Lande L, Milot E, Gribnau J, Grosveld F, Fraser P, Cedar H. Developmental regulation of DNA replication timing at the human beta globin locus. The Embo Journal. 20: 6150-7. PMID 11689454 DOI: 10.1093/Emboj/20.21.6150  1
2001 Ristaldi MS, Drabek D, Gribnau J, Poddie D, Yannoutsous N, Cao A, Grosveld F, Imam AM. The role of the -50 region of the human gamma-globin gene in switching. The Embo Journal. 20: 5242-9. PMID 11566887 DOI: 10.1093/Emboj/20.18.5242  1
2001 Zagoraiou L, Drabek D, Alexaki S, Guy JA, Klinakis AG, Langeveld A, Skavdis G, Mamalaki C, Grosveld F, Savakis C. In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues. Proceedings of the National Academy of Sciences of the United States of America. 98: 11474-8. PMID 11562481 DOI: 10.1073/Pnas.201392398  1
2001 van de Corput MP, Grosveld FG. Fluorescence in situ hybridization analysis of transcript dynamics in cells. Methods (San Diego, Calif.). 25: 111-8. PMID 11559002 DOI: 10.1006/meth.2001.1220  1
2001 Göllner H, Bouwman P, Mangold M, Karis A, Braun H, Rohner I, Del Rey A, Besedovsky HO, Meinhardt A, van den Broek M, Cutforth T, Grosveld F, Philipsen S, Suske G. Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 6: 689-97. PMID 11532028 DOI: 10.1046/J.1365-2443.2001.00455.X  1
2001 Hoogenraad CC, Akhmanova A, Howell SA, Dortland BR, De Zeeuw CI, Willemsen R, Visser P, Grosveld F, Galjart N. Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. The Embo Journal. 20: 4041-54. PMID 11483508 DOI: 10.1093/Emboj/20.15.4041  1
2001 Nawijn MC, Dingjan GM, Ferreira R, Lambrecht BN, Karis A, Grosveld F, Savelkoul H, Hendriks RW. Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo. Journal of Immunology (Baltimore, Md. : 1950). 167: 724-32. PMID 11441076 DOI: 10.4049/Jimmunol.167.2.724  1
2001 Nawijn MC, Ferreira R, Dingjan GM, Kahre O, Drabek D, Karis A, Grosveld F, Hendriks RW. Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 715-23. PMID 11441075 DOI: 10.4049/Jimmunol.167.2.715  1
2001 Koutsourakis M, Keijzer R, Visser P, Post M, Tibboel D, Grosveld F. Branching and differentiation defects in pulmonary epithelium with elevated Gata6 expression. Mechanisms of Development. 105: 105-14. PMID 11429286 DOI: 10.1016/S0925-4773(01)00386-0  1
2001 Dingjan GM, Middendorp S, Dahlenborg K, Maas A, Grosveld F, Hendriks RW. Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse. The Journal of Experimental Medicine. 193: 1169-78. PMID 11369788 DOI: 10.1084/Jem.193.10.1169  1
2001 Akhmanova A, Hoogenraad CC, Drabek K, Stepanova T, Dortland B, Verkerk T, Vermeulen W, Burgering BM, De Zeeuw CI, Grosveld F, Galjart N. Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts. Cell. 104: 923-35. PMID 11290329 DOI: 10.1016/S0092-8674(01)00288-4  1
2001 Keijzer R, van Tuyl M, Meijers C, Post M, Tibboel D, Grosveld F, Koutsourakis M. The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development. Development (Cambridge, England). 128: 503-11. PMID 11171334  1
2001 Karis A, Pata I, van Doorninck JH, Grosveld F, de Zeeuw CI, de Caprona D, Fritzsch B. Transcription factor GATA-3 alters pathway selection of olivocochlear neurons and affects morphogenesis of the ear. The Journal of Comparative Neurology. 429: 615-30. PMID 11135239 DOI: 10.1002/1096-9861(20010122)429:4<615::Aid-Cne8>3.0.Co;2-F  1
2001 van Loo ND, Fortunati E, Ehlert E, Rabelink M, Grosveld F, Scholte BJ. Baculovirus infection of nondividing mammalian cells: mechanisms of entry and nuclear transport of capsids. Journal of Virology. 75: 961-70. PMID 11134309 DOI: 10.1128/Jvi.75.2.961-970.2001  1
2000 Akhmanova A, Verkerk T, Langeveld A, Grosveld F, Galjart N. Characterisation of transcriptionally active and inactive chromatin domains in neurons. Journal of Cell Science. 113: 4463-74. PMID 11082040  1
2000 Tanimoto K, Liu Q, Grosveld F, Bungert J, Engel JD. Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice. Genes & Development. 14: 2778-94. PMID 11069894 DOI: 10.1101/Gad.822500  1
2000 Zafarana G, Rottier R, Grosveld F, Philipsen S. Erythroid overexpression of C/EBPgamma in transgenic mice affects gamma-globin expression and fetal liver erythropoiesis. The Embo Journal. 19: 5856-63. PMID 11060036 DOI: 10.1093/Emboj/19.21.5856  0.48
2000 McMorrow T, van den Wijngaard A, Wollenschlaeger A, van de Corput M, Monkhorst K, Trimborn T, Fraser P, van Lohuizen M, Jenuwein T, Djabali M, Philipsen S, Grosveld F, Milot E. Activation of the beta globin locus by transcription factors and chromatin modifiers. The Embo Journal. 19: 4986-96. PMID 10990462 DOI: 10.1093/Emboj/19.18.4986  1
2000 Whyatt D, Lindeboom F, Karis A, Ferreira R, Milot E, Hendriks R, de Bruijn M, Langeveld A, Gribnau J, Grosveld F, Philipsen S. An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells. Nature. 406: 519-24. PMID 10952313 DOI: 10.1038/35020086  1
2000 Imam AM, Patrinos GP, de Krom M, Bottardi S, Janssens RJ, Katsantoni E, Wai AW, Sherratt DJ, Grosveld FG. Modification of human beta-globin locus PAC clones by homologous recombination in Escherichia coli. Nucleic Acids Research. 28: E65. PMID 10871388  1
2000 Lim KC, Lakshmanan G, Crawford SE, Gu Y, Grosveld F, Engel JD. Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. Nature Genetics. 25: 209-12. PMID 10835639 DOI: 10.1038/76080  1
2000 Hoogenraad CC, Akhmanova A, Grosveld F, De Zeeuw CI, Galjart N. Functional analysis of CLIP-115 and its binding to microtubules. Journal of Cell Science. 113: 2285-97. PMID 10825300  0.68
2000 Bouwman P, Göllner H, Elsässer HP, Eckhoff G, Karis A, Grosveld F, Philipsen S, Suske G. Transcription factor Sp3 is essential for post-natal survival and late tooth development. The Embo Journal. 19: 655-61. PMID 10675334 DOI: 10.1093/Emboj/19.4.655  0.48
1999 Pata I, Studer M, van Doorninck JH, Briscoe J, Kuuse S, Engel JD, Grosveld F, Karis A. The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. Development (Cambridge, England). 126: 5523-31. PMID 10556076  1
1999 Hendriks RW, Nawijn MC, Engel JD, van Doorninck H, Grosveld F, Karis A. Expression of the transcription factor GATA-3 is required for the development of the earliest T cell progenitors and correlates with stages of cellular proliferation in the thymus. European Journal of Immunology. 29: 1912-8. PMID 10382753 DOI: 10.1002/(Sici)1521-4141(199906)29:06<1912::Aid-Immu1912>3.0.Co;2-D  1
1999 van Doorninck JH, van Der Wees J, Karis A, Goedknegt E, Engel JD, Coesmans M, Rutteman M, Grosveld F, De Zeeuw CI. GATA-3 is involved in the development of serotonergic neurons in the caudal raphe nuclei. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: RC12. PMID 10366650 DOI: 10.1523/Jneurosci.19-12-J0002.1999  1
1999 Samakoglu S, Philipsen S, Grosveld F, Lüleci G, Bagci H. Nucleotide changes in the gamma-globin promoter and the (AT)xNy(AT)z polymorphic sequence of beta LCRHS-2 region associated with altered levels of HbF. European Journal of Human Genetics : Ejhg. 7: 345-56. PMID 10234511 DOI: 10.1038/Sj.Ejhg.5200284  0.48
1999 Calzolari R, McMorrow T, Yannoutsos N, Langeveld A, Grosveld F. Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression. The Embo Journal. 18: 949-58. PMID 10022837 DOI: 10.1093/Emboj/18.4.949  1
1999 Lakshmanan G, Lieuw KH, Lim KC, Gu Y, Grosveld F, Engel JD, Karis A. Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus. Molecular and Cellular Biology. 19: 1558-68. PMID 9891089 DOI: 10.1128/Mcb.19.2.1558  1
1998 Lakshmanan G, Lieuw KH, Grosveld F, Engel JD. Partial rescue of GATA-3 by yeast artificial chromosome transgenes. Developmental Biology. 204: 451-63. PMID 9882482 DOI: 10.1006/Dbio.1998.8991  1
1998 Hoogenraad CC, Eussen BH, Langeveld A, van Haperen R, Winterberg S, Wouters CH, Grosveld F, De Zeeuw CI, Galjart N. The murine CYLN2 gene: genomic organization, chromosome localization, and comparison to the human gene that is located within the 7q11.23 Williams syndrome critical region. Genomics. 53: 348-58. PMID 9799601 DOI: 10.1006/Geno.1998.5529  0.68
1998 Gillemans N, Tewari R, Lindeboom F, Rottier R, de Wit T, Wijgerde M, Grosveld F, Philipsen S. Altered DNA-binding specificity mutants of EKLF and Sp1 show that EKLF is an activator of the beta-globin locus control region in vivo. Genes & Development. 12: 2863-73. PMID 9744863 DOI: 10.1101/Gad.12.18.2863  0.48
1998 Levavasseur F, Mandemakers W, Visser P, Broos L, Grosveld F, Zivkovic D, Meijer D. Comparison of sequence and function of the Oct-6 genes in zebrafish, chicken and mouse. Mechanisms of Development. 74: 89-98. PMID 9651490 DOI: 10.1016/S0925-4773(98)00067-7  1
1998 Grosveld F, de Boer E, Dillon N, Gribnau J, McMorrow T, Milot E, Trimborn T, Wijgerde M, Fraser P. The dynamics of globin gene expression and position effects. Novartis Foundation Symposium. 214: 67-79; discussion 79. PMID 9601012 DOI: 10.1002/9780470515501.Ch5  1
1998 Tewari R, Gillemans N, Wijgerde M, Nuez B, von Lindern M, Grosveld F, Philipsen S. Erythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control region. The Embo Journal. 17: 2334-41. PMID 9545245 DOI: 10.1093/Emboj/17.8.2334  0.64
1998 Payen E, Verkerk T, Michalovich D, Dreyer SD, Winterpacht A, Lee B, De Zeeuw CI, Grosveld F, Galjart N. The centromeric/nucleolar chromatin protein ZFP-37 may function to specify neuronal nuclear domains. The Journal of Biological Chemistry. 273: 9099-109. PMID 9535899  0.68
1998 van Leeuwen FW, de Kleijn DP, van den Hurk HH, Neubauer A, Sonnemans MA, Sluijs JA, Köycü S, Ramdjielal RD, Salehi A, Martens GJ, Grosveld FG, Peter J, Burbach H, Hol EM. Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients. Science (New York, N.Y.). 279: 242-7. PMID 9422699 DOI: 10.1126/Science.279.5348.242  1
1997 Whyatt DJ, Karis A, Harkes IC, Verkerk A, Gillemans N, Elefanty AG, Vairo G, Ploemacher R, Grosveld F, Philipsen S. The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery. Genes and Function. 1: 11-24. PMID 9680325  0.48
1997 Koekkoek SK, v Alphen AM, vd Burg J, Grosveld F, Galjart N, De Zeeuw CI. Gain adaptation and phase dynamics of compensatory eye movements in mice. Genes and Function. 1: 175-90. PMID 9680293  0.68
1997 De Zeeuw CI, Hoogenraad CC, Goedknegt E, Hertzberg E, Neubauer A, Grosveld F, Galjart N. CLIP-115, a novel brain-specific cytoplasmic linker protein, mediates the localization of dendritic lamellar bodies. Neuron. 19: 1187-99. PMID 9427243 DOI: 10.1016/S0896-6273(00)80411-0  0.68
1997 Lieuw KH, Li Gl, Zhou Y, Grosveld F, Engel JD. Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements. Developmental Biology. 188: 1-16. PMID 9245507 DOI: 10.1006/Dbio.1997.8575  1
1997 Marin M, Karis A, Visser P, Grosveld F, Philipsen S. Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation. Cell. 89: 619-28. PMID 9160753 DOI: 10.1016/S0092-8674(00)80243-3  0.48
1997 Ma GT, Roth ME, Groskopf JC, Tsai FY, Orkin SH, Grosveld F, Engel JD, Linzer DI. GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. Development (Cambridge, England). 124: 907-14. PMID 9043071  1
1996 Tewari R, Gillemans N, Harper A, Wijgerde M, Zafarana G, Drabek D, Grosveld F, Philipsen S. The human beta-globin locus control region confers an early embryonic erythroid-specific expression pattern to a basic promoter driving the bacterial lacZ gene. Development (Cambridge, England). 122: 3991-9. PMID 9012519  0.48
1996 Wijgerde M, Gribnau J, Trimborn T, Nuez B, Philipsen S, Grosveld F, Fraser P. The role of EKLF in human beta-globin gene competition. Genes & Development. 10: 2894-902. PMID 8918890 DOI: 10.1101/Gad.10.22.2894  0.48
1996 Mazarakis N, Michalovich D, Karis A, Grosveld F, Galjart N. Zfp-37 is a member of the KRAB zinc finger gene family and is expressed in neurons of the developing and adult CNS. Genomics. 33: 247-57. PMID 8660973 DOI: 10.1006/Geno.1996.0189  0.68
1996 Ellis J, Tan-Un KC, Harper A, Michalovich D, Yannoutsos N, Philipsen S, Grosveld F. A dominant chromatin-opening activity in 5' hypersensitive site 3 of the human beta-globin locus control region. The Embo Journal. 15: 562-8. PMID 8599939  0.48
1995 Einerhand MP, Antoniou M, Zolotukhin S, Muzyczka N, Berns KI, Grosveld F, Valerio D. Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transfer. Gene Therapy. 2: 336-43. PMID 7671109  1
1995 Zhou XY, Morreau H, Rottier R, Davis D, Bonten E, Gillemans N, Wenger D, Grosveld FG, Doherty P, Suzuki K, Grosveld GC, d'Azzo A. Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells. Genes & Development. 9: 2623-34. PMID 7590240 DOI: 10.1101/Gad.9.21.2623  1
1995 Pandolfi PP, Roth ME, Karis A, Leonard MW, Dzierzak E, Grosveld FG, Engel JD, Lindenbaum MH. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis. Nature Genetics. 11: 40-4. PMID 7550312 DOI: 10.1038/ng0995-40  1
1994 Foley KP, Pruzina S, Winick JD, Engel JD, Grosveld F, Fraser P. The chicken beta/epsilon-globin enhancer directs autonomously regulated, high-level expression of the chicken epsilon-globin gene in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 91: 7252-6. PMID 8041775 DOI: 10.1073/Pnas.91.15.7252  1
1994 George KM, Leonard MW, Roth ME, Lieuw KH, Kioussis D, Grosveld F, Engel JD. Embryonic expression and cloning of the murine GATA-3 gene. Development (Cambridge, England). 120: 2673-86. PMID 7956841  1
1994 Pruzina S, Antoniou M, Hurst J, Grosveld F, Philipsen S. Transcriptional activation by hypersensitive site three of the human beta-globin locus control region in murine erythroleukemia cells. Biochimica Et Biophysica Acta. 1219: 351-60. PMID 7918632 DOI: 10.1016/0167-4781(94)90059-0  0.48
1993 Wijnholds J, Philipsen S, Pruzina S, Fraser P, Grosveld F, Ab G. Estrogen-inducible and liver-specific expression of the chicken Very Low Density Apolipoprotein II gene locus in transgenic mice. Nucleic Acids Research. 21: 1629-35. PMID 8479914 DOI: 10.1093/Nar/21.7.1629  1
1993 Philipsen S, Pruzina S, Grosveld F. The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region. The Embo Journal. 12: 1077-85. PMID 8458325 DOI: 10.1002/J.1460-2075.1993.Tb05749.X  0.48
1993 Whyatt DJ, deBoer E, Grosveld F. The two zinc finger-like domains of GATA-1 have different DNA binding specificities. The Embo Journal. 12: 4993-5005. PMID 8262042 DOI: 10.1002/J.1460-2075.1993.Tb06193.X  1
1991 Pruzina S, Hanscombe O, Whyatt D, Grosveld F, Philipsen S. Hypersensitive site 4 of the human beta globin locus control region. Nucleic Acids Research. 19: 1413-9. PMID 2027748 DOI: 10.1093/Nar/19.7.1413  0.48
1990 Talbot D, Philipsen S, Fraser P, Grosveld F. Detailed analysis of the site 3 region of the human beta-globin dominant control region. The Embo Journal. 9: 2169-77. PMID 2357965 DOI: 10.1002/J.1460-2075.1990.Tb07386.X  0.48
1990 Philipsen S, Talbot D, Fraser P, Grosveld F. The beta-globin dominant control region: hypersensitive site 2. The Embo Journal. 9: 2159-67. PMID 2357964 DOI: 10.1002/J.1460-2075.1990.Tb07385.X  0.48
1989 Spanopoulou E, Early A, Elliott J, Crispe N, Ladyman H, Ritter M, Watt S, Grosveld F, Kioussis D. Complex lymphoid and epithelial thymic tumours in Thyl-myc transgenic mice Nature. 342: 185-189. PMID 2572968 DOI: 10.1038/342185A0  1
1988 Julien JP, Côté F, Beaudet L, Sidky M, Flavell D, Grosveld F, Mushynski W. Sequence and structure of the mouse gene coding for the largest neurofilament subunit. Gene. 68: 307-14. PMID 3220257 DOI: 10.1016/0378-1119(88)90033-9  1
1987 Hurst J, Flavell D, Julien JP, Meijer D, Mushynski W, Grosveld F. The human neurofilament gene (NEFL) is located on the short arm of chromosome 8. Cytogenetics and Cell Genetics. 45: 30-2. PMID 3036423 DOI: 10.1159/000132421  1
1987 Julien JP, Grosveld F, Yazdanbaksh K, Flavell D, Meijer D, Mushynski W. The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament gene family. Biochimica Et Biophysica Acta. 909: 10-20. PMID 3034332 DOI: 10.1016/0167-4781(87)90041-8  1
1984 Hui K, Grosveld F, Festenstein H. Rejection of transplantable AKR leukaemia cells following MHC DNA-mediated cell transformation Nature. 311: 750-752. PMID 6333639 DOI: 10.1038/311750A0  1
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