Robbert Havekes, Ph.D. - Publications

2015- Biology University of Groningen, Groningen, Netherlands 
Learning and memory, Sleep, synaptic plasticity, Hippocampus

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bolsius YG, Zurbriggen MD, Kim JK, Kas MJ, Meerlo P, Aton SJ, Havekes R. The role of clock genes in sleep, stress and memory. Biochemical Pharmacology. 114493. PMID 33647263 DOI: 10.1016/j.bcp.2021.114493  1
2020 Heckman PRA, Roig Kuhn F, Meerlo P, Havekes R. A brief period of sleep deprivation negatively impacts the acquisition, consolidation, and retrieval of object-location memories. Neurobiology of Learning and Memory. 175: 107326. PMID 33059032 DOI: 10.1016/j.nlm.2020.107326  1
2020 Kelly MP, Heckman PRA, Havekes R. Genetic manipulation of cyclic nucleotide signaling during hippocampal neuroplasticity and memory formation. Progress in Neurobiology. 101799. PMID 32360536 DOI: 10.1016/J.Pneurobio.2020.101799  0.56
2020 Bridi MS, Schoch H, Florian C, Poplawski SG, Banerjee A, Hawk JD, Banks GS, Lejards C, Hahn CG, Giese KP, Havekes R, Spruston N, Abel T. Transcriptional co-repressor Sin3a regulates hippocampal synaptic plasticity via Homer1/mGluR5. Jci Insight. PMID 32069266 DOI: 10.1172/Jci.Insight.92385  1
2020 Heckman PRA, Roig Kuhn F, Raven F, Bolsius YG, Prickaerts J, Meerlo P, Havekes R. Phosphodiesterase inhibitors roflumilast and vardenafil prevent sleep deprivation-induced deficits in spatial pattern separation. Synapse (New York, N.Y.). e22150. PMID 32056276 DOI: 10.1002/Syn.22150  1
2020 van der Vlag M, Havekes R, Heckman PRA. The contribution of Parkin, PINK1 and DJ-1 genes to selective neuronal degeneration in Parkinson's disease. The European Journal of Neuroscience. PMID 31991026 DOI: 10.1111/Ejn.14689  0.56
2020 Raven F, Bolsius YG, van Renssen LV, Meijer EL, van der Zee EA, Meerlo P, Havekes R. Elucidating the role of protein synthesis in hippocampus-dependent memory consolidation across the day and night. The European Journal of Neuroscience. PMID 31965655 DOI: 10.1111/Ejn.14684  1
2019 Raven F, Heckman PRA, Havekes R, Meerlo P. Sleep deprivation-induced impairment of memory consolidation is not mediated by glucocorticoid stress hormones. Journal of Sleep Research. e12972. PMID 31845433 DOI: 10.1111/Jsr.12972  1
2019 Havekes R, Heckman PRA, Wams EJ, Stasiukonyte N, Meerlo P, Eisel ULM. Alzheimer's disease pathogenesis: The role of disturbed sleep in attenuated brain plasticity and neurodegenerative processes. Cellular Signalling. 109420. PMID 31536750 DOI: 10.1016/J.Cellsig.2019.109420  1
2019 El Aidy S, Bolsius YG, Raven F, Havekes R. A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota. Journal of Sleep Research. e12920. PMID 31515894 DOI: 10.1111/Jsr.12920  1
2019 Havekes R, Aton S, Tudor JC, Meerlo P. NLM Special Issue on Sleep and hippocampal function. Neurobiology of Learning and Memory. 160: 1-2. PMID 31023441 DOI: 10.1016/J.Nlm.2019.03.009  1
2018 Kumar VJ, Grissom NM, McKee SE, Schoch H, Bowman N, Havekes R, Kumar M, Pickup S, Poptani H, Reyes TM, Hawrylycz M, Abel T, Nickl-Jockschat T. Linking spatial gene expression patterns to sex-specific brain structural changes on a mouse model of 16p11.2 hemideletion. Translational Psychiatry. 8: 109. PMID 29844452 DOI: 10.1038/S41398-018-0157-Z  1
2018 Raven F, Meerlo P, Van der Zee EA, Abel T, Havekes R. A brief period of sleep deprivation causes spine loss in the dentate gyrus of mice. Neurobiology of Learning and Memory. PMID 29588221 DOI: 10.1016/J.Nlm.2018.03.018  1
2018 Raven F, Van der Zee EA, Meerlo P, Havekes R. The role of sleep in regulating structural plasticity and synaptic strength: Implications for memory and cognitive function. Sleep Medicine Reviews. 39: 3-11. PMID 28641933 DOI: 10.1016/J.Smrv.2017.05.002  1
2017 Grissom NM, McKee SE, Schoch H, Bowman N, Havekes R, O'Brien WT, Mahrt E, Siegel S, Commons K, Portfors C, Nickl-Jockschat T, Reyes TM, Abel T. Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders. Molecular Psychiatry. PMID 29038598 DOI: 10.1038/Mp.2017.184  1
2017 Park AJ, Havekes R, Fu X, Hansen R, Tudor JC, Peixoto L, Li Z, Wu YC, Poplawski SG, Baraban JM, Abel T. Learning induces the translin/trax RNase complex to express activin receptors for persistent memory. Elife. 6. PMID 28927503 DOI: 10.7554/Elife.27872  1
2017 Vogel Ciernia A, Kramár EA, Matheos DP, Havekes R, Hemstedt TJ, Magnan CN, Sakata K, Tran A, Azzawi S, Lopez A, Dang R, Wang W, Trieu B, Tong J, Barrett RM, et al. Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 199-209. PMID 28416631 DOI: 10.1101/Lm.044602.116  1
2017 Havekes R, Abel T. The tired hippocampus: the molecular impact of sleep deprivation on hippocampal function. Current Opinion in Neurobiology. 44: 13-19. PMID 28242433 DOI: 10.1016/J.Conb.2017.02.005  1
2016 Havekes R, Park AJ, Tolentino RE, Bruinenberg VM, Tudor JC, Lee Y, Hansen RT, Guercio LA, Linton E, Neves-Zaph SR, Meerlo P, Baillie GS, Houslay MD, Abel T. Compartmentalized PDE4A5 Signaling Impairs Hippocampal Synaptic Plasticity and Long-Term Memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8936-46. PMID 27559174 DOI: 10.1523/Jneurosci.0248-16.2016  1
2016 Havekes R, Park AJ, Tudor JC, Luczak VG, Hansen RT, Ferri SL, Bruinenberg VM, Poplawski SG, Day JP, Aton SJ, Radwańska K, Meerlo P, Houslay MD, Baillie GS, Abel T. Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1. Elife. 5. PMID 27549340 DOI: 10.7554/Elife.13424  1
2016 Tudor JC, Davis EJ, Peixoto L, Wimmer ME, van Tilborg E, Park AJ, Poplawski SG, Chung CW, Havekes R, Huang J, Gatti E, Pierre P, Abel T. Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis. Science Signaling. 9: ra41. PMID 27117251 DOI: 10.1126/Scisignal.Aad4949  1
2015 Kreutzmann JC, Havekes R, Abel T, Meerlo P. Sleep deprivation and hippocampal vulnerability: changes in neuronal plasticity, neurogenesis and cognitive function. Neuroscience. PMID 25937398 DOI: 10.1016/J.Neuroscience.2015.04.053  1
2015 Havekes R, Meerlo P, Abel T. Animal studies on the role of sleep in memory: from behavioral performance to molecular mechanisms. Current Topics in Behavioral Neurosciences. 25: 183-206. PMID 25680961 DOI: 10.1007/7854_2015_369  1
2015 Meerlo P, Havekes R, Steiger A. Chronically restricted or disrupted sleep as a causal factor in the development of depression. Current Topics in Behavioral Neurosciences. 25: 459-81. PMID 25646723 DOI: 10.1007/7854_2015_367  1
2014 Havekes R, Bruinenberg VM, Tudor JC, Ferri SL, Baumann A, Meerlo P, Abel T. Transiently increasing cAMP levels selectively in hippocampal excitatory neurons during sleep deprivation prevents memory deficits caused by sleep loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15715-21. PMID 25411499 DOI: 10.1523/Jneurosci.2403-14.2014  1
2014 Park AJ, Havekes R, Choi JH, Luczak V, Nie T, Huang T, Abel T. A presynaptic role for PKA in synaptic tagging and memory. Neurobiology of Learning and Memory. 114: 101-12. PMID 24882624 DOI: 10.1016/J.Nlm.2014.05.005  1
2014 Prince TM, Wimmer M, Choi J, Havekes R, Aton S, Abel T. Sleep deprivation during a specific 3-hour time window post-training impairs hippocampal synaptic plasticity and memory. Neurobiology of Learning and Memory. 109: 122-30. PMID 24380868 DOI: 10.1016/J.Nlm.2013.11.021  1
2013 Abel T, Havekes R, Saletin JM, Walker MP. Sleep, plasticity and memory from molecules to whole-brain networks. Current Biology : Cb. 23: R774-88. PMID 24028961 DOI: 10.1016/J.Cub.2013.07.025  1
2013 Vecsey CG, Wimmer ME, Havekes R, Park AJ, Perron IJ, Meerlo P, Abel T. Daily acclimation handling does not affect hippocampal long-term potentiation or cause chronic sleep deprivation in mice. Sleep. 36: 601-7. PMID 23565007 DOI: 10.5665/Sleep.2556  1
2012 Havekes R, Canton DA, Park AJ, Huang T, Nie T, Day JP, Guercio LA, Grimes Q, Luczak V, Gelman IH, Baillie GS, Scott JD, Abel T. Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18137-49. PMID 23238728 DOI: 10.1523/Jneurosci.3612-12.2012  1
2012 Havekes R, Vecsey CG, Abel T. The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity. Cellular Signalling. 24: 1251-60. PMID 22570866 DOI: 10.1016/J.Cellsig.2012.02.010  1
2011 Kim M, Park AJ, Havekes R, Chay A, Guercio LA, Oliveira RF, Abel T, Blackwell KT. Colocalization of protein kinase A with adenylyl cyclase enhances protein kinase A activity during induction of long-lasting long-term-potentiation. Plos Computational Biology. 7: e1002084. PMID 21738458 DOI: 10.1371/Journal.Pcbi.1002084  1
2011 Havekes R, Abel T, Van der Zee EA. The cholinergic system and neostriatal memory functions. Behavioural Brain Research. 221: 412-23. PMID 21129408 DOI: 10.1016/J.Bbr.2010.11.047  1
2010 Hagewoud R, Havekes R, Tiba PA, Novati A, Hogenelst K, Weinreder P, Van der Zee EA, Meerlo P. Coping with sleep deprivation: shifts in regional brain activity and learning strategy. Sleep. 33: 1465-73. PMID 21102988 DOI: 10.1093/Sleep/33.11.1465  1
2010 Hagewoud R, Whitcomb SN, Heeringa AN, Havekes R, Koolhaas JM, Meerlo P. A time for learning and a time for sleep: the effect of sleep deprivation on contextual fear conditioning at different times of the day. Sleep. 33: 1315-22. PMID 21061853 DOI: 10.1093/Sleep/33.10.1315  1
2010 Oliveira AM, Hawk JD, Abel T, Havekes R. Post-training reversible inactivation of the hippocampus enhances novel object recognition memory. Learning & Memory (Cold Spring Harbor, N.Y.). 17: 155-60. PMID 20189960 DOI: 10.1101/Lm.1625310  1
2010 Hagewoud R, Havekes R, Novati A, Keijser JN, Van der Zee EA, Meerlo P. Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation. Journal of Sleep Research. 19: 280-8. PMID 20050994 DOI: 10.1111/J.1365-2869.2009.00799.X  1
2009 Tretter V, Revilla-Sanchez R, Houston C, Terunuma M, Havekes R, Florian C, Jurd R, Vithlani M, Michels G, Couve A, Sieghart W, Brandon N, Abel T, Smart TG, Moss SJ. Deficits in spatial memory correlate with modified {gamma}-aminobutyric acid type A receptor tyrosine phosphorylation in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 106: 20039-44. PMID 19903874 DOI: 10.1073/Pnas.0908840106  1
2009 Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, et al. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature. 461: 1122-5. PMID 19847264 DOI: 10.1038/Nature08488  1
2009 Havekes R, Abel T. Genetic dissection of neural circuits and behavior in Mus musculus. Advances in Genetics. 65: 1-38. PMID 19615530 DOI: 10.1016/S0065-2660(09)65001-X  1
2008 Isiegas C, McDonough C, Huang T, Havekes R, Fabian S, Wu LJ, Xu H, Zhao MG, Kim JI, Lee YS, Lee HR, Ko HG, Lee N, Choi SL, Lee JS, et al. A novel conditional genetic system reveals that increasing neuronal cAMP enhances memory and retrieval. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6220-30. PMID 18550764 DOI: 10.1523/Jneurosci.2935-07.2008  1
2008 Van der Zee EA, Havekes R, Barf RP, Hut RA, Nijholt IM, Jacobs EH, Gerkema MP. Circadian time-place learning in mice depends on Cry genes. Current Biology : Cb. 18: 844-8. PMID 18514517 DOI: 10.1016/J.Cub.2008.04.077  1
2008 Havekes R, Nijholt IM, Visser AK, Eisel UL, Van der Zee EA. Transgenic inhibition of neuronal calcineurin activity in the forebrain facilitates fear conditioning, but inhibits the extinction of contextual fear memories. Neurobiology of Learning and Memory. 89: 595-8. PMID 17884610 DOI: 10.1016/J.Nlm.2007.08.003  1
2007 Van der Borght K, Havekes R, Bos T, Eggen BJ, Van der Zee EA. Exercise improves memory acquisition and retrieval in the Y-maze task: relationship with hippocampal neurogenesis. Behavioral Neuroscience. 121: 324-34. PMID 17469921 DOI: 10.1037/0735-7044.121.2.324  1
2007 Havekes R, Timmer M, Van der Zee EA. Regional differences in hippocampal PKA immunoreactivity after training and reversal training in a spatial Y-maze task. Hippocampus. 17: 338-48. PMID 17315197 DOI: 10.1002/Hipo.20272  1
2006 Havekes R, Nijholt IM, Luiten PG, Van der Zee EA. Differential involvement of hippocampal calcineurin during learning and reversal learning in a Y-maze task. Learning & Memory (Cold Spring Harbor, N.Y.). 13: 753-9. PMID 17101875 DOI: 10.1101/Lm.323606  1
2006 van der Borght K, Ferrari F, Klauke K, Roman V, Havekes R, Sgoifo A, van der Zee EA, Meerlo P. Hippocampal cell proliferation across the day: increase by running wheel activity, but no effect of sleep and wakefulness. Behavioural Brain Research. 167: 36-41. PMID 16214238 DOI: 10.1016/J.Bbr.2005.08.012  1
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