Susan L. Ackerman - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Genetics, neurodegeneration

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kapur M, Ganguly A, Nagy G, Adamson SI, Chuang JH, Frankel WN, Ackerman SL. Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility. Neuron. PMID 32853550 DOI: 10.1016/J.Neuron.2020.07.023  0.383
2020 Griffin EN, Ackerman SL. Lipid Metabolism and Axon Degeneration: An ACOX1 Balancing Act. Neuron. 106: 551-553. PMID 32437651 DOI: 10.1016/J.Neuron.2020.04.030  0.361
2018 Vo MN, Terrey M, Lee JW, Roy B, Moresco JJ, Sun L, Fu H, Liu Q, Weber TG, Yates JR, Fredrick K, Schimmel P, Ackerman SL. ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase. Nature. PMID 29769718 DOI: 10.1038/S41586-018-0137-8  0.396
2018 Kapur M, Ackerman SL. mRNA Translation Gone Awry: Translation Fidelity and Neurological Disease. Trends in Genetics : Tig. PMID 29352613 DOI: 10.1016/J.Tig.2017.12.007  0.321
2017 Kapur M, Monaghan CE, Ackerman SL. Regulation of mRNA Translation in Neurons-A Matter of Life and Death. Neuron. 96: 616-637. PMID 29096076 DOI: 10.1016/J.Neuron.2017.09.057  0.359
2017 Ackerman SL. Abstract IA13: Ribosome stalling and disease Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-Ia13  0.325
2016 Ishimura R, Nagy G, Dotu I, Chuang JH, Ackerman SL. Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation. Elife. 5. PMID 27085088 DOI: 10.7554/Elife.14295  0.37
2016 Garrett AM, Jucius TJ, Sigaud LP, Tang FL, Xiong WC, Ackerman SL, Burgess RW. Analysis of Expression Pattern and Genetic Deletion of Netrin5 in the Developing Mouse. Frontiers in Molecular Neuroscience. 9: 3. PMID 26858598 DOI: 10.3389/Fnmol.2016.00003  0.392
2015 Poliak S, Morales D, Croteau LP, Krawchuk D, Palmesino E, Morton S, Jean-François C, Charron F, Dalva MB, Ackerman SL, Kao TJ, Kania A. Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons. Elife. 4. PMID 26633881 DOI: 10.7554/Elife.10841  0.32
2015 Liu Y, Lee JW, Ackerman SL. Mutations in the microtubule-associated protein 1A (Map1a) gene cause Purkinje cell degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4587-98. PMID 25788676 DOI: 10.1523/Jneurosci.2757-14.2015  0.435
2015 Jia Y, Jucius TJ, Cook SA, Ackerman SL. Loss of Clcc1 results in ER stress, misfolded protein accumulation, and neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3001-9. PMID 25698737 DOI: 10.1523/Jneurosci.3678-14.2015  0.4
2015 Poliak S, Morales D, Croteau L, Krawchuk D, Palmesino E, Morton S, Cloutier J, Charron F, Dalva MB, Ackerman SL, Kao T, Kania A. Author response: Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons Elife. DOI: 10.7554/Elife.10841.021  0.319
2014 Liu Y, Satz JS, Vo MN, Nangle LA, Schimmel P, Ackerman SL. Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy. Proceedings of the National Academy of Sciences of the United States of America. 111: 17570-5. PMID 25422440 DOI: 10.1073/Pnas.1420196111  0.376
2014 Ishimura R, Nagy G, Dotu I, Zhou H, Yang XL, Schimmel P, Senju S, Nishimura Y, Chuang JH, Ackerman SL. RNA function. Ribosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration. Science (New York, N.Y.). 345: 455-9. PMID 25061210 DOI: 10.1126/Science.1249749  0.379
2014 Srivatsa S, Parthasarathy S, Britanova O, Bormuth I, Donahoo AL, Ackerman SL, Richards LJ, Tarabykin V. Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation. Nature Communications. 5: 3708. PMID 24739528 DOI: 10.1038/Ncomms4708  0.367
2013 Nagy G, Ackerman SL. Cholesterol metabolism and Rett syndrome pathogenesis. Nature Genetics. 45: 965-7. PMID 23985682 DOI: 10.1038/Ng.2738  0.338
2013 Liu Y, Zaun HC, Orlowski J, Ackerman SL. CHP1-mediated NHE1 biosynthetic maturation is required for Purkinje cell axon homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 12656-69. PMID 23904602 DOI: 10.1523/Jneurosci.0406-13.2013  0.365
2013 Natarajan S, Li Y, Miller EE, Shih DJ, Taylor MD, Stearns TM, Bronson RT, Ackerman SL, Yoon JK, Yun K. Notch1-induced brain tumor models the sonic hedgehog subgroup of human medulloblastoma. Cancer Research. 73: 5381-90. PMID 23852537 DOI: 10.1158/0008-5472.Can-13-0033  0.311
2012 Jia Y, Mu JC, Ackerman SL. Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration. Cell. 148: 296-308. PMID 22265417 DOI: 10.1016/J.Cell.2011.11.057  0.39
2011 Zhao L, Spassieva SD, Jucius TJ, Shultz LD, Shick HE, Macklin WB, Hannun YA, Obeid LM, Ackerman SL. A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation. Plos Genetics. 7: e1002063. PMID 21625621 DOI: 10.1371/Journal.Pgen.1002063  0.407
2011 Kim D, Ackerman SL. The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons Journal of Neuroscience. 31: 2167-2179. PMID 21307253 DOI: 10.1523/Jneurosci.5254-10.2011  0.378
2011 Stum M, McLaughlin HM, Kleinbrink EL, Miers KE, Ackerman SL, Seburn KL, Antonellis A, Burgess RW. An assessment of mechanisms underlying peripheral axonal degeneration caused by aminoacyl-tRNA synthetase mutations. Molecular and Cellular Neurosciences. 46: 432-43. PMID 21115117 DOI: 10.1016/J.Mcn.2010.11.006  0.42
2010 Zhao L, Rosales C, Seburn K, Ron D, Ackerman SL. Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome. Human Molecular Genetics. 19: 25-35. PMID 19801575 DOI: 10.1093/Hmg/Ddp464  0.351
2008 Ackerman SL, Cox GA. From ER to Eph Receptors: New Roles for VAP Fragments Cell. 133: 949-951. PMID 18555770 DOI: 10.1016/J.Cell.2008.05.028  0.3
2008 Ishimura R, Martin GR, Ackerman SL. Loss of apoptosis-inducing factor results in cell-type-specific neurogenesis defects. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4938-48. PMID 18463247 DOI: 10.1523/Jneurosci.0229-08.2008  0.397
2008 Renaud J, Kerjan G, Sumita I, Zagar Y, Georget V, Kim D, Fouquet C, Suda K, Sanbo M, Suto F, Ackerman SL, Mitchell KJ, Fujisawa H, Chédotal A. Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells. Nature Neuroscience. 11: 440-9. PMID 18327254 DOI: 10.1038/Nn2064  0.306
2008 Hu Z, Shanker S, MacLean JA, Ackerman SL, Wilkinson MF. The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c. The Journal of Biological Chemistry. 283: 3866-76. PMID 18077458 DOI: 10.1074/Jbc.M706717200  0.373
2007 Dillon AK, Jevince AR, Hinck L, Ackerman SL, Lu X, Tessier-Lavigne M, Kaprielian Z. UNC5C is required for spinal accessory motor neuron development. Molecular and Cellular Neurosciences. 35: 482-9. PMID 17543537 DOI: 10.1016/J.Mcn.2007.04.011  0.343
2006 Lee JW, Beebe K, Nangle LA, Jang J, Longo-Guess CM, Cook SA, Davisson MT, Sundberg JP, Schimmel P, Ackerman SL. Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration. Nature. 443: 50-5. PMID 16906134 DOI: 10.1038/Nature05096  0.401
2006 Burgess RW, Jucius TJ, Ackerman SL. Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5756-66. PMID 16723533 DOI: 10.1523/Jneurosci.0736-06.2006  0.346
2006 Xie Y, Hong Y, Ma XY, Ren XR, Ackerman S, Mei L, Xiong WC. DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation. The Journal of Biological Chemistry. 281: 2605-11. PMID 16321979 DOI: 10.1074/Jbc.M512767200  0.331
2005 Xie Y, Ding YQ, Hong Y, Feng Z, Navarre S, Xi CX, Zhu XJ, Wang CL, Ackerman SL, Kozlowski D, Mei L, Xiong WC. Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth. Nature Cell Biology. 7: 1124-32. PMID 16244667 DOI: 10.1038/Ncb1321  0.408
2005 Zhao L, Longo-Guess C, Harris BS, Lee JW, Ackerman SL. Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nature Genetics. 37: 974-9. PMID 16116427 DOI: 10.1038/Ng1620  0.405
2005 van Empel VPM, Bertrand AT, van der Nagel R, Kostin S, Doevendans PA, Crijns HJ, de Wit E, Sluiter W, Ackerman SL, De Windt LJ. Downregulation of apoptosis-inducing factor in harlequin mutant mice sensitizes the myocardium to oxidative stress-related cell death and pressure overload-induced decompensation Circulation Research. 96: e92-e101. PMID 15933268 DOI: 10.1161/01.Res.0000172081.30327.28  0.336
2004 Munroe RJ, Ackerman SL, Schimenti JC. Genomewide two-generation screens for recessive mutations by ES cell mutagenesis Mammalian Genome. 15: 960-965. PMID 15599554 DOI: 10.1007/S00335-004-2406-0  0.326
2004 Herrup K, Neve R, Ackerman SL, Copani A. Divide and die: cell cycle events as triggers of nerve cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9232-9. PMID 15496657 DOI: 10.1523/Jneurosci.3347-04.2004  0.311
2004 Schwarting GA, Raitcheva D, Bless EP, Ackerman SL, Tobet S. Netrin 1-mediated chemoattraction regulates the migratory pathway of LHRH neurons European Journal of Neuroscience. 19: 11-20. PMID 14750959 DOI: 10.1111/J.1460-9568.2004.03094.X  0.392
2003 Klein JA, Ackerman SL. Oxidative stress, cell cycle, and neurodegeneration Journal of Clinical Investigation. 111: 785-793. PMID 12639981 DOI: 10.1172/Jci18182  0.313
2002 Klein JA, Longo-Guess CM, Rossmann MP, Seburn KL, Hurd RE, Frankel WN, Bronson RT, Ackerman SL. The harlequin mouse mutation downregulates apoptosis-inducing factor Nature. 419: 367-374. PMID 12353028 DOI: 10.1038/Nature01034  0.409
2002 Park C, Falls W, Finger JH, Longo-Guess CM, Ackerman SL. Deletion in Catna2, encoding αN-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation Nature Genetics. 31: 279-284. PMID 12089526 DOI: 10.1038/Ng908  0.376
2002 Park C, Finger JH, Cooper JA, Ackerman SL. The cerebellar deficient folia (cdf) gene acts intrinsically in Purkinje cell migrations Genesis. 32: 32-41. PMID 11835672 DOI: 10.1002/Gene.10024  0.419
2002 Finger JH, Bronson RT, Harris B, Johnson K, Przyborski SA, Ackerman SL. The netrin 1 receptors Unc5h3 and Dcc are necessary at multiple choice points for the guidance of corticospinal tract axons. The Journal of Neuroscience. 22: 10346-10356. DOI: 10.1523/Jneurosci.22-23-10346.2002  0.367
2001 Barclay J, Balaguero N, Mione M, Ackerman SL, Letts VA, Brodbeck J, Canti C, Meir A, Page KM, Kusumi K, Perez-Reyes E, Lander ES, Frankel WN, Gardiner RM, Dolphin AC, et al. Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6095-104. PMID 11487633 DOI: 10.1523/Jneurosci.21-16-06095.2001  0.322
2001 Beierbach E, Park C, Ackerman SL, Goldowitz D, Hawkes R. Abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf). The Journal of Comparative Neurology. 436: 42-51. PMID 11413545 DOI: 10.1002/Cne.1052  0.317
2001 Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, Lussier-Cacan S, Chen MF, Pai A, John SW, Smith RS, Bottiglieri T, Bagley P, Selhub J, Rudnicki MA, James SJ, et al. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Human Molecular Genetics. 10: 433-43. PMID 11181567 DOI: 10.1093/Hmg/10.5.433  0.327
2001 Näf D, Wilson LA, Bergstrom RA, Smith RS, Goodwin NC, Verkerk A, van Ommen GJ, Ackerman SL, Frankel WN, Schimenti JC. Mouse models for the Wolf-Hirschhorn deletion syndrome. Human Molecular Genetics. 10: 91-8. PMID 11152656 DOI: 10.1093/Hmg/10.2.91  0.323
2000 Park C, Longo CM, Ackerman SL. Genetic and physical mapping of the cerebellar deficient folia (cdf) locus on mouse chromosome 6 Genomics. 69: 135-138. PMID 11013084 DOI: 10.1006/Geno.2000.6322  0.33
2000 Goldowitz D, Hamre KM, Przyborski SA, Ackerman SL. Granule cells and cerebellar boundaries: analysis of Unc5h3 mutant chimeras. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 4129-37. PMID 10818148 DOI: 10.1523/Jneurosci.20-11-04129.2000  0.364
1998 Ackerman SL, Knowles BB. Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23. Genomics. 52: 205-8. PMID 9782087 DOI: 10.1006/Geno.1998.5425  0.338
1998 Przyborski SA, Knowles BB, Handel MA, Gurwitch SA, Ackerman SL. Differential expression of the zinc finger gene Zfp105 during spermatogenesis. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 9: 758-62. PMID 9716663 DOI: 10.1007/S003359900859  0.328
1997 Ackerman SL, Kozak LP, Przyborski SA, Rund LA, Boyer BB, Knowles BB. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein. Nature. 386: 838-42. PMID 9126743 DOI: 10.1038/386838A0  0.443
1997 Leonardo ED, Hinck L, Masu M, Keino-Masu K, Ackerman SL, Tessier-Lavigne M. Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors. Nature. 386: 833-8. PMID 9126742 DOI: 10.1038/386833A0  0.386
1996 Hwang S, Benjamin LE, Oh B, Rothstein JL, Ackerman SL, Beddington RS, Solter D, Knowles BB. Genetic mapping and embryonic expression of a novel, maternally transcribed gene Mem3. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 586-90. PMID 8678978 DOI: 10.1007/S003359900174  0.306
1994 Ackerman SL, Knowles BB, Andrews PW. Gene regulation during neuronal and non-neuronal differentiation of NTERA2 human teratocarcinoma-derived stem cells Molecular Brain Research. 25: 157-162. PMID 7984043 DOI: 10.1016/0169-328X(94)90293-3  0.358
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