Robert Jan Lebbink - Publications

Affiliations: 
2006-2020 University of California, San Francisco, San Francisco, CA 

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tromp AT, Van Gent M, Jansen JP, Scheepmaker LM, Velthuizen A, De Haas CJC, Van Kessel KPM, Bardoel BW, Boettcher M, McManus MT, Van Strijp JAG, Lebbink RJ, Haas PA, Spaan AN. Host-Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity. Toxins. 12. PMID 32041354 DOI: 10.3390/Toxins12020106  0.668
2019 Tang J, Frascaroli G, Lebbink RJ, Ostermann E, Brune W. Human cytomegalovirus glycoprotein B variants affect viral entry, cell fusion, and genome stability. Proceedings of the National Academy of Sciences of the United States of America. PMID 31427511 DOI: 10.1073/Pnas.1907447116  0.311
2019 Luteijn RD, van Diemen F, Blomen VA, Boer IGJ, Manikam Sadasivam S, van Kuppevelt TH, Drexler I, Brummelkamp TR, Lebbink RJ, Wiertz EJ. A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection. Journal of Virology. 93. PMID 30996093 DOI: 10.1128/Jvi.02160-18  0.341
2018 Tromp AT, Van Gent M, Abrial P, Martin A, Jansen JP, De Haas CJC, Van Kessel KPM, Bardoel BW, Kruse E, Bourdonnay E, Boettcher M, McManus MT, Day CJ, Jennings MP, Lina G, ... ... Lebbink RJ, et al. Publisher Correction: Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton-Valentine leukocidin. Nature Microbiology. PMID 30177744 DOI: 10.1038/S41564-018-0247-Y  0.617
2018 de Buhr H, Lebbink RJ. Harnessing CRISPR to combat human viral infections. Current Opinion in Immunology. 54: 123-129. PMID 30056335 DOI: 10.1016/J.Coi.2018.06.002  0.362
2018 Praest P, Luteijn RD, Brak-Boer IGJ, Lanfermeijer J, Hoelen H, Ijgosse L, Costa AI, Gorham RD, Lebbink RJ, Wiertz EJHJ. The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins. Molecular Immunology. 101: 55-64. PMID 29879547 DOI: 10.1016/J.Molimm.2018.05.025  0.366
2018 Luteijn RD, Drexler I, Smith GL, Lebbink RJ, Wiertz EJHJ. Mutagenic repair of double-stranded DNA breaks in vaccinia virus genomes requires cellular DNA ligase IV activity in the cytosol. The Journal of General Virology. PMID 29676720 DOI: 10.1099/Jgv.0.001034  0.31
2018 Döhner K, Ramos-Nascimento A, Bialy D, Anderson F, Hickford-Martinez A, Rother F, Koithan T, Rudolph K, Buch A, Prank U, Binz A, Hügel S, Lebbink RJ, Hoeben RC, Hartmann E, et al. Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons. Plos Pathogens. 14: e1006823. PMID 29304174 DOI: 10.1371/Journal.Ppat.1006823  0.323
2017 Soppe JA, Lebbink RJ. Antiviral Goes Viral: Harnessing CRISPR/Cas9 to Combat Viruses in Humans. Trends in Microbiology. 25: 833-850. PMID 28522157 DOI: 10.1016/J.Tim.2017.04.005  0.354
2017 Hooykaas MJG, van Gent M, Soppe JA, Kruse E, Boer IGJ, van Leenen D, Groot Koerkamp MJA, Holstege FCP, Ressing ME, Wiertz EJHJ, Lebbink RJ. EBV MicroRNA BART16 Suppresses Type I IFN Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 28416598 DOI: 10.4049/Jimmunol.1501605  0.361
2017 Diemen FRv, Lebbink RJ. CRISPR/Cas9, a powerful tool to target human herpesviruses. Cellular Microbiology. 19. PMID 27860066 DOI: 10.1111/Cmi.12694  0.311
2016 van de Weijer ML, van Muijlwijk GH, Visser LJ, Costa AI, Wiertz EJ, Lebbink RJ. The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein. Viruses. 8. PMID 27854284 DOI: 10.3390/V8110309  0.368
2016 Hooykaas MJ, Kruse E, Wiertz EJ, Lebbink RJ. Comprehensive profiling of functional Epstein-Barr virus miRNA expression in human cell lines. Bmc Genomics. 17: 644. PMID 27531524 DOI: 10.1186/S12864-016-2978-6  0.322
2016 van Diemen FR, Kruse EM, Hooykaas MJ, Bruggeling CE, Schürch AC, van Ham PM, Imhof SM, Nijhuis M, Wiertz EJ, Lebbink RJ. CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections. Plos Pathogens. 12: e1005701. PMID 27362483 DOI: 10.1371/Journal.Ppat.1005701  0.342
2016 Sebestyen Z, Scheper W, Vyborova A, Gu S, Rychnavska Z, Schiffler M, Cleven A, Chéneau C, van Noorden M, Peigné CM, Olive D, Lebbink RJ, Oostvogels R, Mutis T, Schuurhuis GJ, et al. RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor. Cell Reports. PMID 27210746 DOI: 10.1016/J.Celrep.2016.04.081  0.342
2016 Gram AM, Oosenbrug T, Lindenbergh MF, Büll C, Comvalius A, Dickson KJ, Wiegant J, Vrolijk H, Lebbink RJ, Wolterbeek R, Adema GJ, Griffioen M, Heemskerk MH, Tscharke DC, Hutt-Fletcher LM, et al. The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells. Plos Pathogens. 12: e1005550. PMID 27077376 DOI: 10.1371/Journal.Ppat.1005550  0.351
2016 Holm CK, Rahbek SH, Gad HH, Bak RO, Jakobsen MR, Jiang Z, Hansen AL, Jensen SK, Sun C, Thomsen MK, Laustsen A, Nielsen CG, Severinsen K, Xiong Y, Burdette DL, ... ... Lebbink RJ, et al. Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses. Nature Communications. 7: 10680. PMID 26893169 DOI: 10.1038/Ncomms10680  0.305
2015 Benedictus L, Luteijn RD, Otten H, Lebbink RJ, Kooten PJSv, Wiertz EJHJ, Rutten VPMG, Koets AP. Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression. Scientific Reports. 5: 12748-12748. PMID 26235972 DOI: 10.1038/Srep12748  0.338
2015 Hoelen H, Zaldumbide A, van Leeuwen WF, Torfs EC, Engelse MA, Hassan C, Lebbink RJ, de Koning EJ, Resssing ME, de Ru AH, van Veelen PA, Hoeben RC, Roep BO, Wiertz EJ. Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97. Plos One. 10: e0128206. PMID 26107514 DOI: 10.1371/Journal.Pone.0128206  0.336
2015 D'Astolfo DS, Pagliero RJ, Pras A, Karthaus WR, Clevers H, Prasad V, Lebbink RJ, Rehmann H, Geijsen N. Efficient intracellular delivery of native proteins. Cell. 161: 674-90. PMID 25910214 DOI: 10.1016/J.Cell.2015.03.028  0.373
2015 van Gent M, Gram AM, Boer IG, Geerdink RJ, Lindenbergh MF, Lebbink RJ, Wiertz EJ, Ressing ME. Silencing the shutoff protein of Epstein-Barr virus in productively infected B cells points to (innate) targets for immune evasion. The Journal of General Virology. 96: 858-65. PMID 25502648 DOI: 10.1099/Jgv.0.000021  0.399
2014 Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M. Systematic identification of barriers to human iPSC generation. Cell. 158: 449-61. PMID 25036638 DOI: 10.1016/J.Cell.2014.05.040  0.578
2014 Luteijn RD, Hoelen H, Kruse E, van Leeuwen WF, Grootens J, Horst D, Koorengevel M, Drijfhout JW, Kremmer E, Früh K, Neefjes JJ, Killian A, Lebbink RJ, Ressing ME, Wiertz EJ. Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP. Journal of Immunology (Baltimore, Md. : 1950). 193: 1578-89. PMID 25024387 DOI: 10.4049/Jimmunol.1400964  0.332
2014 van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, ... Lebbink RJ, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nature Communications. 5: 3832. PMID 24807418 DOI: 10.1038/Ncomms4832  0.651
2013 Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 152: 909-22. PMID 23394947 DOI: 10.1016/J.Cell.2013.01.030  0.638
2011 Lebbink RJ, Lowe M, Chan T, Khine H, Wang X, McManus MT. Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs. Plos One. 6: e26213. PMID 22031824 DOI: 10.1371/Journal.Pone.0026213  0.563
2010 Steevels TA, Lebbink RJ, Westerlaken GH, Coffer PJ, Meyaard L. Signal inhibitory receptor on leukocytes-1 is a novel functional inhibitory immune receptor expressed on human phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 184: 4741-8. PMID 20375307 DOI: 10.4049/Jimmunol.0902039  0.374
2010 Brondijk TH, de Ruiter T, Ballering J, Wienk H, Lebbink RJ, van Ingen H, Boelens R, Farndale RW, Meyaard L, Huizinga EG. Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI. Blood. 115: 1364-73. PMID 20007810 DOI: 10.1182/Blood-2009-10-246322  0.306
2009 Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nature Methods. 6: 443-5. PMID 19448642 DOI: 10.1038/Nmeth.1330  0.673
2009 Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. The Journal of Biological Chemistry. 284: 18515-24. PMID 19419954 DOI: 10.1074/Jbc.M109.006676  0.604
2009 Lebbink RJ, Raynal N, de Ruiter T, Bihan DG, Farndale RW, Meyaard L. Identification of multiple potent binding sites for human leukocyte associated Ig-like receptor LAIR on collagens II and III. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 202-10. PMID 19345263 DOI: 10.1016/J.Matbio.2009.03.005  0.335
2008 Lebbink RJ, van den Berg MC, de Ruiter T, Raynal N, van Roon JA, Lenting PJ, Jin B, Meyaard L. The soluble leukocyte-associated Ig-like receptor (LAIR)-2 antagonizes the collagen/LAIR-1 inhibitory immune interaction. Journal of Immunology (Baltimore, Md. : 1950). 180: 1662-9. PMID 18209062 DOI: 10.4049/Jimmunol.180.3.1662  0.39
2007 Lebbink RJ, de Ruiter T, Kaptijn GJ, Bihan DG, Jansen CA, Lenting PJ, Meyaard L. Mouse leukocyte-associated Ig-like receptor-1 (mLAIR-1) functions as an inhibitory collagen-binding receptor on immune cells. International Immunology. 19: 1011-9. PMID 17702987 DOI: 10.1093/Intimm/Dxm071  0.386
2007 Lebbink RJ, Meyaard L. Non-MHC ligands for inhibitory immune receptors: Novel insights and implications for immune regulation Molecular Immunology. 44: 2153-2164. PMID 17188357 DOI: 10.1016/J.Molimm.2006.11.014  0.349
2006 Lebbink RJ, de Ruiter T, Adelmeijer J, Brenkman AB, van Helvoort JM, Koch M, Farndale RW, Lisman T, Sonnenberg A, Lenting PJ, Meyaard L. Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1. The Journal of Experimental Medicine. 203: 1419-25. PMID 16754721 DOI: 10.1084/Jem.20052554  0.357
2005 Lebbink RJ, de Ruiter T, Kaptijn GJ, Meyaard L. Identification and characterization of the rat homologue of LAIR-1. Immunogenetics. 57: 344-51. PMID 15902436 DOI: 10.1007/S00251-005-0804-4  0.32
2004 Lebbink RJ, Ruiter Td, Verbrugge A, Bril WS, Meyaard L. The Mouse Homologue of the Leukocyte-Associated Ig-Like Receptor-1 Is an Inhibitory Receptor That Recruits Src Homology Region 2-Containing Protein Tyrosine Phosphatase (SHP)-2, but Not SHP-1 Journal of Immunology. 172: 5535-5543. PMID 15100296 DOI: 10.4049/Jimmunol.172.9.5535  0.37
2002 Brinkman AB, Bell SD, Lebbink RJ, de Vos WM, van der Oost J. The Sulfolobus solfataricus Lrp-like protein LysM regulates lysine biosynthesis in response to lysine availability. The Journal of Biological Chemistry. 277: 29537-49. PMID 12042311 DOI: 10.1074/Jbc.M203528200  0.368
2001 IJkel WF, Lebbink RJ, Op den Brouw ML, Goldbach RW, Vlak JM, Zuidema D. Identification of a novel occlusion derived virus-specific protein in Spodoptera exigua multicapsid nucleopolyhedrovirus. Virology. 284: 170-81. PMID 11384217 DOI: 10.1006/Viro.2001.0906  0.348
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