| Year |
Citation |
Score |
| 2023 |
Orfanoudaki M, Smith EA, Hill NT, Garman KA, Brownell I, Copp BR, Grkovic T, Henrich CJ. An Investigation of Structure-Activity Relationships and Cell Death Mechanisms of the Marine Alkaloids Discorhabdins in Merkel Cell Carcinoma Cells. Marine Drugs. 21. PMID 37755087 DOI: 10.3390/md21090474 |
0.663 |
|
| 2023 |
Cadelis MM, Copp BR. Marine pyridoacridine, pyridoacridone and pyrroloacridine alkaloids. The Alkaloids. Chemistry and Biology. 90: 97-157. PMID 37716797 DOI: 10.1016/bs.alkal.2023.06.001 |
0.343 |
|
| 2023 |
Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. 40: 275-325. PMID 36786022 DOI: 10.1039/d2np00083k |
0.37 |
|
| 2023 |
Cadelis MM, Li SA, van de Pas SJ, Grey A, Mulholland D, Weir BS, Copp BR, Wiles S. Antimicrobial Natural Products from Plant Pathogenic Fungi. Molecules (Basel, Switzerland). 28. PMID 36770808 DOI: 10.3390/molecules28031142 |
0.337 |
|
| 2022 |
Li SA, Zheng RJ, Sue K, Bourguet-Kondracki ML, Troudi A, Brunel JM, Copp BR, Cadelis MM. Discovery and Preliminary Structure-Activity Investigation of 3-Substituted-1-imidazol-5-yl-1-indoles with In Vitro Activity towards Methicillin-Resistant . Antibiotics (Basel, Switzerland). 11. PMID 36290109 DOI: 10.3390/antibiotics11101450 |
0.306 |
|
| 2022 |
Cadelis M, Grey A, van de Pas S, Geese S, Weir BS, Copp B, Wiles S. Terrien, a metabolite made by , has activity against . Peerj. 10: e14239. PMID 36275475 DOI: 10.7717/peerj.14239 |
0.317 |
|
| 2022 |
Chen D, Park DJ, Cadelis MM, Douafer H, Bourguet-Kondracki ML, Brunel JM, Copp BR. Total Synthesis of the Four Stereoisomers of Cyclo(l-Trp-l-Arg) Raises Uncertainty of the Structures of the Natural Products and Invalidates Their Promising Antimicrobial Activities. Molecules (Basel, Switzerland). 27. PMID 36144649 DOI: 10.3390/molecules27185913 |
0.313 |
|
| 2022 |
Li SA, Cadelis MM, Deed RC, Douafer H, Bourguet-Kondracki ML, Michel Brunel J, Copp BR. Valorisation of the diterpene podocarpic acid - Antibiotic and antibiotic enhancing activities of polyamine conjugates. Bioorganic & Medicinal Chemistry. 64: 116762. PMID 35477062 DOI: 10.1016/j.bmc.2022.116762 |
0.333 |
|
| 2022 |
Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 35201245 DOI: 10.1039/d1np00076d |
0.396 |
|
| 2021 |
Grey ABJ, Cadelis MM, Diao Y, Park D, Lumley T, Weir BS, Copp BR, Wiles S. Screening of Fungi for Antimycobacterial Activity Using a Medium-Throughput Bioluminescence-Based Assay. Frontiers in Microbiology. 12: 739995. PMID 34552577 DOI: 10.3389/fmicb.2021.739995 |
0.305 |
|
| 2021 |
Cadelis MM, Gordon H, Grey A, Geese S, Mulholland DR, Weir BS, Copp BR, Wiles S. Isolation of a Novel Polyketide from sp. Molecules (Basel, Switzerland). 26. PMID 34072211 DOI: 10.3390/molecules26113235 |
0.32 |
|
| 2021 |
Pearce AN, Chen D, Edmeades LR, Cadelis MM, Troudi A, Brunel JM, Bourguet-Kondracki ML, Copp BR. Repurposing primaquine as a polyamine conjugate to become an antibiotic adjuvant. Bioorganic & Medicinal Chemistry. 38: 116110. PMID 33831695 DOI: 10.1016/j.bmc.2021.116110 |
0.488 |
|
| 2021 |
Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 33570537 DOI: 10.1039/d0np00089b |
0.389 |
|
| 2020 |
Cadelis MM, Copp BR, Wiles S. A Review of Fungal Protoilludane Sesquiterpenoid Natural Products. Antibiotics (Basel, Switzerland). 9. PMID 33352728 DOI: 10.3390/antibiotics9120928 |
0.365 |
|
| 2020 |
Cadelis MM, Geese S, Gris L, Weir BS, Copp BR, Wiles S. A Revised Structure and Assigned Absolute Configuration of Theissenolactone A. Molecules (Basel, Switzerland). 25. PMID 33092217 DOI: 10.3390/molecules25204823 |
0.353 |
|
| 2020 |
Lam CFC, Cadelis MM, Copp BR. Exploration of the Electrophilic Reactivity of the Cytotoxic Marine Alkaloid Discorhabdin C and Subsequent Discovery of a New Dimeric C-1/N-13-Linked Discorhabdin Natural Product. Marine Drugs. 18. PMID 32752009 DOI: 10.3390/Md18080404 |
0.676 |
|
| 2020 |
Barker D, Lee S, Varnava KG, Sparrow K, van Rensburg M, Deed RC, Cadelis MM, Li SA, Copp BR, Sarojini V, Pilkington LI. Synthesis and Antibacterial Analysis of Analogues of the Marine Alkaloid Pseudoceratidine. Molecules (Basel, Switzerland). 25. PMID 32545320 DOI: 10.3390/Molecules25112713 |
0.452 |
|
| 2020 |
Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 32025684 DOI: 10.1039/c9np00069k |
0.395 |
|
| 2020 |
Mayer A, Barker D, Copp BR, Miskelly GM. The HONO-methamphetamine adduct – an unexpected derivative Forensic Chemistry. 20: 100276. DOI: 10.1016/J.Forc.2020.100276 |
0.33 |
|
| 2019 |
Cadelis MM, Pike EIW, Kang W, Wu Z, Bourguet-Kondracki ML, Blanchet M, Vidal N, Brunel JM, Copp BR. Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines. European Journal of Medicinal Chemistry. 183: 111708. PMID 31550659 DOI: 10.1016/J.Ejmech.2019.111708 |
0.353 |
|
| 2019 |
Kellner Filho LC, Picão BW, Silva MLA, Cunha WR, Pauletti PM, Dias GM, Copp BR, Bertanha CS, Januario AH. Bioactive Aliphatic Sulfates from Marine Invertebrates. Marine Drugs. 17. PMID 31505775 DOI: 10.3390/Md17090527 |
0.425 |
|
| 2019 |
Pearce AN, Hill CAE, Page MJ, Keyzers RA, Copp BR. An Acetylenic Lipid from the New Zealand Ascidian : Exemplification of an Improved Workflow for Determination of Absolute Configuration of Long-Chain 2-Amino-3-alkanols. Journal of Natural Products. PMID 31356078 DOI: 10.1021/Acs.Jnatprod.9B00504 |
0.551 |
|
| 2019 |
Li SA, Cadelis MM, Sue K, Blanchet M, Vidal N, Brunel JM, Bourguet-Kondracki ML, Copp BR. 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. Bioorganic & Medicinal Chemistry. PMID 30975502 DOI: 10.1016/J.Bmc.2019.04.004 |
0.361 |
|
| 2019 |
Molinski TF, Salib MN, Pearce AN, Copp BR. The Configuration of Distaminolyne A is S: Quantitative Evaluation of Exciton Coupling Circular Dichroism of N, O- Bis-arenoyl-1-amino-2-alkanols. Journal of Natural Products. PMID 30958674 DOI: 10.1021/Acs.Jnatprod.8B00937 |
0.535 |
|
| 2019 |
Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 30663727 DOI: 10.1039/c8np00092a |
0.385 |
|
| 2019 |
Johnson C, Copp B, Lewis A. New psychoactive substances seized at the New Zealand border Australian Journal of Forensic Sciences. 51: S214-S216. DOI: 10.1080/00450618.2019.1571102 |
0.303 |
|
| 2018 |
Pearce AN, Copp BR, Molinski TF. Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols. Molecules (Basel, Switzerland). 24. PMID 30591663 DOI: 10.3390/Molecules24010090 |
0.5 |
|
| 2018 |
Cadelis MM, Copp BR. Investigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds. Beilstein Journal of Organic Chemistry. 14: 2229-2235. PMID 30202476 DOI: 10.3762/Bjoc.14.197 |
0.393 |
|
| 2018 |
Blunt JW, Carroll AR, Copp BR, Davis RA, Keyzers RA, Prinsep MR. Marine natural products. Natural Product Reports. PMID 29335692 DOI: 10.1039/c7np00052a |
0.61 |
|
| 2018 |
Fong HK, Cadelis MM, Brunel JM, Bourguet-Kondracki M, Barker D, Copp BR. Alaninyl variants of the marine natural product halocyamine A and their antibacterial properties Tetrahedron. 74: 6929-6938. DOI: 10.1016/J.Tet.2018.10.021 |
0.402 |
|
| 2018 |
van Rensburg M, Copp BR, Barker D. Front Cover: Synthesis and Absolute Stereochemical Reassignment of Mukanadin F: A Study of Isomerization of Bromopyrrole Alkaloids with Implications on Marine Natural Product Isolation (Eur. J. Org. Chem. 24/2018) European Journal of Organic Chemistry. 2018: 3049-3049. DOI: 10.1002/Ejoc.201800935 |
0.393 |
|
| 2018 |
van Rensburg M, Copp BR, Barker D. Synthesis and Absolute Stereochemical Reassignment of Mukanadin F: A Study of Isomerization of Bromopyrrole Alkaloids with Implications on Marine Natural Product Isolation European Journal of Organic Chemistry. 2018: 3065-3074. DOI: 10.1002/Ejoc.201800422 |
0.392 |
|
| 2017 |
Pearce AN, Kaiser M, Copp BR. Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates. European Journal of Medicinal Chemistry. 140: 595-603. PMID 28988153 DOI: 10.1016/J.Ejmech.2017.09.040 |
0.52 |
|
| 2017 |
Davidson SJ, Pearce AN, Copp BR, Barker D. Total Synthesis of (-)-Bicubebin A, B, (+)-Bicubebin C and Structural Reassignment of (-)-cis-Cubebin. Organic Letters. PMID 28901148 DOI: 10.1021/Acs.Orglett.7B02644 |
0.544 |
|
| 2017 |
Tempone AG, Ferreira DD, Lima ML, Costa Silva TA, Borborema SET, Reimão JQ, Galuppo MK, Guerra JM, Russell AJ, Wynne GM, Lai RYL, Cadelis MM, Copp BR. Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi. European Journal of Medicinal Chemistry. 139: 947-960. PMID 28881289 DOI: 10.1016/J.Ejmech.2017.08.055 |
0.324 |
|
| 2017 |
Fong HKH, Brunel JM, Longeon A, Bourguet-Kondracki ML, Barker D, Copp BR. Synthesis and biological evaluation of the ascidian blood-pigment halocyamine A. Organic & Biomolecular Chemistry. PMID 28695949 DOI: 10.1039/C7Ob01122A |
0.409 |
|
| 2017 |
Cadelis MM, Bourguet-Kondracki ML, Dubois J, Kaiser M, Brunel JM, Barker D, Copp BR. Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase. Bioorganic & Medicinal Chemistry. PMID 28666857 DOI: 10.1016/J.Bmc.2017.06.029 |
0.471 |
|
| 2017 |
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 34: 235-294. PMID 28290569 DOI: 10.1039/c6np00124f |
0.747 |
|
| 2017 |
Lam CF, Cadelis MM, Copp BR. Exploration of the influence of spiro-dienone moiety on biological activity of the cytotoxic marine alkaloid discorhabdin P Tetrahedron. 73: 4779-4785. DOI: 10.1016/J.Tet.2017.06.057 |
0.66 |
|
| 2016 |
Phummarin N, Boshoff HI, Tsang PS, Dalton J, Wiles S, Barry Rd CE, Copp BR. SAR and identification of 2-(quinolin-4-yloxy)acetamides as Mycobacterium tuberculosis cytochrome bc1 inhibitors. Medchemcomm. 7: 2122-2127. PMID 28337336 DOI: 10.1039/C6Md00236F |
0.348 |
|
| 2016 |
Cadelis MM, Khalil IM, Harper JL, Shaw L, Dubois J, Valentin A, Bourguet-Kondracki ML, Barker D, Copp BR. Structure-activity relationships of bioactive marine natural products leading to the identification of more potent non-natural analogues - the meroterpenoids, thiaplidiaquinones A and B. Planta Medica. 81: S1-S381. PMID 27976307 DOI: 10.1055/S-0036-1596124 |
0.692 |
|
| 2016 |
Cadelis MM, Bourguet-Kondracki ML, Dubois J, Valentin A, Barker D, Copp BR. Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors. Bioorganic & Medicinal Chemistry. 24: 3102-7. PMID 27240468 DOI: 10.1016/J.Bmc.2016.05.024 |
0.437 |
|
| 2016 |
Goey AK, Chau CH, Sissung TM, Cook KM, Venzon DJ, Castro A, Ransom TR, Henrich CJ, McKee TC, McMahon JB, Grkovic T, Cadelis MM, Copp BR, Gustafson KR, Figg WD. Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction. Journal of Natural Products. PMID 27140429 DOI: 10.1021/Acs.Jnatprod.5B00846 |
0.674 |
|
| 2016 |
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 33: 382-431. PMID 26837534 DOI: 10.1039/c5np00156k |
0.747 |
|
| 2016 |
Khalil IM, Barker D, Copp BR. Bioinspired Syntheses of the Pyridoacridine Marine Alkaloids Demethyldeoxyamphimedine, Deoxyamphimedine, and Amphimedine. The Journal of Organic Chemistry. 81: 282-9. PMID 26642369 DOI: 10.1021/Acs.Joc.5B02312 |
0.643 |
|
| 2015 |
Wang J, Pearce AN, Chan ST, Taylor RB, Page MJ, Valentin A, Bourguet-Kondracki ML, Dalton JP, Wiles S, Copp BR. Biologically Active Acetylenic Amino Alcohol and N-Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum. Journal of Natural Products. PMID 26670413 DOI: 10.1021/Acs.Jnatprod.5B00770 |
0.789 |
|
| 2015 |
Yeung L, Pilkington LI, Cadelis MM, Copp BR, Barker D. Total synthesis of panicein A2. Beilstein Journal of Organic Chemistry. 11: 1991-6. PMID 26664619 DOI: 10.3762/Bjoc.11.215 |
0.312 |
|
| 2015 |
Harper JL, Khalil IM, Shaw L, Bourguet-Kondracki ML, Dubois J, Valentin A, Barker D, Copp BR. Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B. Marine Drugs. 13: 5102-10. PMID 26266415 DOI: 10.3390/Md13085102 |
0.686 |
|
| 2015 |
He F, Mai LH, Longeon A, Copp BR, Loaëc N, Bescond A, Meijer L, Bourguet-Kondracki ML. Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp. Marine Drugs. 13: 2617-28. PMID 25927661 DOI: 10.3390/Md13052617 |
0.403 |
|
| 2015 |
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 32: 116-211. PMID 25620233 DOI: 10.1039/c4np00144c |
0.756 |
|
| 2015 |
Wang J, Prinsep MR, Gordon DP, Page MJ, Copp BR. Isolation and stereospecific synthesis of janolusimide B from a New Zealand collection of the bryozoan Bugula flabellata. Journal of Natural Products. 78: 530-3. PMID 25494238 DOI: 10.1021/Np500752Y |
0.595 |
|
| 2015 |
Pullar M, Copp B. The synthesis of dehydrodopamine containing marine natural products Planta Medica. 81. DOI: 10.1055/S-0035-1556346 |
0.41 |
|
| 2015 |
Cadelis M, Barker D, Copp B. Synthesis and chemical reactivity of α,β-unsaturated carbonyl fragments related to the marine natural product onchidal Planta Medica. 81. DOI: 10.1055/S-0035-1556345 |
0.339 |
|
| 2015 |
Fong H, Barker D, Copp B. Synthesis of marine natural products that contain a CIS-enamide fragment Planta Medica. 81. DOI: 10.1055/S-0035-1556344 |
0.359 |
|
| 2015 |
Pullar MA, Barker D, Copp BR. Synthesis of tunichrome Sp-1 Tetrahedron Letters. 56: 5604-5606. DOI: 10.1016/J.Tetlet.2015.08.047 |
0.352 |
|
| 2015 |
Chan ST, Pullar MA, Khalil IM, Allouche E, Barker D, Copp BR. Bio-inspired dimerisation of prenylated quinones directed towards the synthesis of the meroterpenoid natural products, the scabellones Tetrahedron Letters. 56: 1486-1488. DOI: 10.1016/J.Tetlet.2015.02.024 |
0.741 |
|
| 2014 |
Wang J, Kaiser M, Copp BR. Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents. Marine Drugs. 12: 3138-60. PMID 24879541 DOI: 10.3390/Md12063138 |
0.529 |
|
| 2014 |
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 31: 160-258. PMID 24389707 DOI: 10.1039/c3np70117d |
0.762 |
|
| 2014 |
Tempone A, Reimao J, Rong C, Copp B. α-Pyrone as a marine scaffold for the synthesis of new antileishmanial and antitrypanosomal compounds Planta Medica. 80. DOI: 10.1055/S-0034-1394720 |
0.433 |
|
| 2014 |
Liew LP, Fleming JM, Longeon A, Mouray E, Florent I, Bourguet-Kondracki M, Copp BR. Synthesis of 1-indolyl substituted β-carboline natural products and discovery of antimalarial and cytotoxic activities Tetrahedron. 70: 4910-4920. DOI: 10.1016/J.Tet.2014.05.068 |
0.684 |
|
| 2014 |
Liew LPP, Fleming JM, Longeon A, Mouray E, Florent I, Bourguet-Kondracki M, Copp BR. ChemInform Abstract: Synthesis of 1-Indolyl Substituted β-Carboline Natural Products and Discovery of Antimalarial and Cytotoxic Activities. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201451207 |
0.644 |
|
| 2013 |
Lam CF, Pearce AN, Tan SH, Kaiser M, Copp BR. Discovery and evaluation of thiazinoquinones as anti-protozoal agents. Marine Drugs. 11: 3472-99. PMID 24022732 DOI: 10.3390/Md11093472 |
0.724 |
|
| 2013 |
Liew LP, Pearce AN, Kaiser M, Copp BR. Synthesis and in vitro and in vivo evaluation of antimalarial polyamines. European Journal of Medicinal Chemistry. 69: 22-31. PMID 23995215 DOI: 10.1016/J.Ejmech.2013.07.055 |
0.729 |
|
| 2013 |
Fong HK, Copp BR. Synthesis, DNA binding and antitumor evaluation of styelsamine and cystodytin analogues. Marine Drugs. 11: 274-99. PMID 23358307 DOI: 10.3390/Md11020274 |
0.349 |
|
| 2013 |
Liew LP, Kaiser M, Copp BR. Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds. Bioorganic & Medicinal Chemistry Letters. 23: 452-4. PMID 23265884 DOI: 10.1016/J.Bmcl.2012.11.072 |
0.699 |
|
| 2013 |
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 30: 237-323. PMID 23263727 DOI: 10.1039/c2np20112g |
0.762 |
|
| 2013 |
Grkovic T, Copp BR. Establishment of a Phenotypic-based Sand DollarFellaster zelandiaeEmbryo Development Assay and its Application in Defining the Structure-Activity Relationship of Discorhabdin Alkaloids Natural Product Communications. 8: 1934578X1300800. DOI: 10.1177/1934578X1300800604 |
0.71 |
|
| 2013 |
Wang J, Liew L, Pearce A, Kaiser M, Copp B. From Natural Products to Potential Drug Leads: Antimalarials from NZ Marine Organisms Planta Medica. 79. DOI: 10.1055/S-0033-1348533 |
0.487 |
|
| 2013 |
Dickson E, Copp BR, Barker D. Rapid synthesis of indole cis-enamides via hydroamidation of indolic alkynes Tetrahedron Letters. 54: 5239-5242. DOI: 10.1016/J.Tetlet.2013.07.081 |
0.331 |
|
| 2012 |
Khalil IM, Barker D, Copp BR. Biomimetic synthesis of thiaplidiaquinones A and B. Journal of Natural Products. 75: 2256-60. PMID 23214418 DOI: 10.1021/Np300790G |
0.663 |
|
| 2012 |
Lam CF, Grkovic T, Pearce AN, Copp BR. Investigation of the electrophilic reactivity of the cytotoxic marine alkaloid discorhabdin B. Organic & Biomolecular Chemistry. 10: 3092-7. PMID 22395232 DOI: 10.1039/C2Ob07090A |
0.795 |
|
| 2012 |
McCracken ST, Kaiser M, Boshoff HI, Boyd PD, Copp BR. Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers. Bioorganic & Medicinal Chemistry. 20: 1482-93. PMID 22285027 DOI: 10.1016/J.Bmc.2011.12.053 |
0.673 |
|
| 2012 |
Blunt JW, Copp BR, Keyzers RA, Munro MH, Prinsep MR. Marine natural products. Natural Product Reports. 29: 144-222. PMID 22193773 DOI: 10.1039/c2np00090c |
0.756 |
|
| 2012 |
Cadelis M, Barker D, Copp B. The central role of chromenols in the biomimetic synthesis of structurally diverse natural product scaffolds Planta Medica. 78. DOI: 10.1055/S-0032-1320252 |
0.39 |
|
| 2012 |
Copp B, Cadelis M, Barker D. Synthesis of Hemitectol, Tectol, and Tecomaquinone I Synlett. 23: 2939-2942. DOI: 10.1055/S-0032-1317541 |
0.429 |
|
| 2012 |
Lam CFC, Giddens AC, Chand N, Webb VL, Copp BR. Semi-synthesis of bioactive fluorescent analogues of the cytotoxic marine alkaloid discorhabdin C Tetrahedron. 68: 3187-3194. DOI: 10.1016/J.Tet.2012.02.052 |
0.79 |
|
| 2011 |
Chan ST, Pearce AN, Januario AH, Page MJ, Kaiser M, McLaughlin RJ, Harper JL, Webb VL, Barker D, Copp BR. Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum. The Journal of Organic Chemistry. 76: 9151-6. PMID 21958335 DOI: 10.1021/Jo201654H |
0.767 |
|
| 2011 |
Chan ST, Pearce AN, Page MJ, Kaiser M, Copp BR. Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum. Journal of Natural Products. 74: 1972-9. PMID 21846091 DOI: 10.1021/Np200509G |
0.772 |
|
| 2011 |
Longeon A, Copp BR, Quévrain E, Roué M, Kientz B, Cresteil T, Petek S, Debitus C, Bourguet-Kondracki ML. Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios sp. Marine Drugs. 9: 879-88. PMID 21673896 DOI: 10.3390/Md9050879 |
0.422 |
|
| 2011 |
Finlayson R, Pearce AN, Page MJ, Kaiser M, Bourguet-Kondracki ML, Harper JL, Webb VL, Copp BR. Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. Journal of Natural Products. 74: 888-92. PMID 21348447 DOI: 10.1021/Np1008619 |
0.611 |
|
| 2011 |
Wang J, Bourguet-Kondracki ML, Longeon A, Dubois J, Valentin A, Copp BR. Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles. Bioorganic & Medicinal Chemistry Letters. 21: 1261-4. PMID 21256013 DOI: 10.1016/J.Bmcl.2010.12.056 |
0.541 |
|
| 2011 |
Blunt JW, Copp BR, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 28: 196-268. PMID 21152619 DOI: 10.1039/c005001f |
0.692 |
|
| 2011 |
Finlayson R, Brackovic A, Simon-Levert A, Banaigs B, O'Toole RF, Miller CH, Copp BR. Establishment of the absolute configuration of the bioactive marine alkaloid eudistomin X by stereospecific synthesis Tetrahedron Letters. 52: 837-840. DOI: 10.1016/J.Tetlet.2010.12.052 |
0.397 |
|
| 2010 |
Grkovic T, Pearce AN, Munro MH, Blunt JW, Davies-Coleman MT, Copp BR. Isolation and characterization of diastereomers of discorhabdins H and K and assignment of absolute configuration to discorhabdins D, N, Q, S, T, and U. Journal of Natural Products. 73: 1686-93. PMID 20860391 DOI: 10.1021/Np100443C |
0.784 |
|
| 2010 |
Longeon A, Copp BR, Roué M, Dubois J, Valentin A, Petek S, Debitus C, Bourguet-Kondracki ML. New bioactive halenaquinone derivatives from South Pacific marine sponges of the genus Xestospongia. Bioorganic & Medicinal Chemistry. 18: 6006-11. PMID 20634081 DOI: 10.1016/J.Bmc.2010.06.066 |
0.478 |
|
| 2010 |
Blunt JW, Copp BR, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 27: 165-237. PMID 20111802 DOI: 10.1039/b906091j |
0.761 |
|
| 2010 |
Appleton DR, Pearce AN, Copp BR. anti-Tuberculosis natural products: synthesis and biological evaluation of pyridoacridine alkaloids related to ascididemin Tetrahedron. 66: 4977-4986. DOI: 10.1016/J.Tet.2010.05.033 |
0.733 |
|
| 2010 |
Lindsay BS, Christiansen HC, Copp BR. ChemInform Abstract: Structural Studies of Cytotoxic Marine Alkaloids: Synthesis of Novel Ring-E Analogues of Ascididemin and Their in vitro and in vivo Biological Evaluation. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200019198 |
0.8 |
|
| 2010 |
Copp BR, Hansen RP, Appleton DR, Lindsay BS, Squire CJ, Clark GR, Rickard CEF. ChemInform Abstract: A Convenient New Route to 4-Substituted Benzo[de][3,6]phenanthrolin-6(6H)-ones: Important Intermediates in the Synthesis of Ring-A Analogues of the Cytotoxic Marine Alkaloid Ascididemin. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199938201 |
0.795 |
|
| 2010 |
LINDSAY BS, PEARCE AN, COPP BR. ChemInform Abstract: Efficient and Convenient Pyridine Ring-E Formation of the Cytotoxic Marine Alkaloid Ascididemin and Related Analogues. Cheminform. 28: no-no. DOI: 10.1002/CHIN.199742264 |
0.79 |
|
| 2009 |
Appleton DR, Chuen CS, Berridge MV, Webb VL, Copp BR. Rossinones A and B, biologically active meroterpenoids from the Antarctic ascidian, Aplidium species. The Journal of Organic Chemistry. 74: 9195-8. PMID 19863121 DOI: 10.1021/Jo901846J |
0.707 |
|
| 2009 |
Blunt JW, Copp BR, Hu WP, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 26: 170-244. PMID 19177222 DOI: 10.1039/b805113p |
0.755 |
|
| 2009 |
Grkovic T, Copp BR. New natural products in the discorhabdin A- and B-series from New Zealand-sourced Latrunculia spp. sponges Tetrahedron. 65: 6335-6340. DOI: 10.1016/J.Tet.2009.06.012 |
0.684 |
|
| 2008 |
Grkovic T, Ding Y, Li XC, Webb VL, Ferreira D, Copp BR. Enantiomeric discorhabdin alkaloids and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra. The Journal of Organic Chemistry. 73: 9133-6. PMID 18855481 DOI: 10.1021/Jo801622N |
0.69 |
|
| 2008 |
Chia EW, Pearce AN, Berridge MV, Larsen L, Perry NB, Sansom CE, Godfrey CA, Hanton LR, Lu GL, Walton M, Denny WA, Webb VL, Copp BR, Harper JL. Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis. Bioorganic & Medicinal Chemistry. 16: 9432-42. PMID 18835721 DOI: 10.1016/J.Bmc.2008.09.052 |
0.579 |
|
| 2008 |
Blunt JW, Copp BR, Hu WP, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 25: 35-94. PMID 18250897 DOI: 10.1039/b701534h |
0.764 |
|
| 2008 |
Grkovic T, Li X, Ding Y, Ferreira D, Copp B. The first enantiomeric discorhabdin alkaloids and determination of absolute configuration using TDDFT calculations of electronic circular dichroism data Planta Medica. 74. DOI: 10.1055/S-0028-1083912 |
0.627 |
|
| 2008 |
Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Harper JL, Webb VL, Copp BR. Orthidines A-E, tubastrine, 3,4-dimethoxyphenethyl-β-guanidine, and 1,14-sperminedihomovanillamide: potential anti-inflammatory alkaloids isolated from the New Zealand ascidian Aplidium orthium that act as inhibitors of neutrophil respiratory burst Tetrahedron. 64: 5748-5755. DOI: 10.1016/J.Tet.2008.04.012 |
0.618 |
|
| 2008 |
Giddens AC, Nielsen L, Boshoff HI, Tasdemir D, Perozzo R, Kaiser M, Wang F, Sacchettini JC, Copp BR. Natural product inhibitors of fatty acid biosynthesis: synthesis of the marine microbial metabolites pseudopyronines A and B and evaluation of their anti-infective activities Tetrahedron. 64: 1242-1249. DOI: 10.1016/J.Tet.2007.11.075 |
0.81 |
|
| 2008 |
Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Harper JL, Webb VL, Copp BR. ChemInform Abstract: Orthidines A-E, Tubastrine, 3,4-Dimethoxyphenethyl-β-guanidine, and 1,14-Sperminedihomovanillamide: Potential Antiinflammatory Alkaloids Isolated from the New Zealand Ascidian Aplidium orthium that Act as Inhibitors of Neutrophil Respiratory Burst. Cheminform. 39. DOI: 10.1002/CHIN.200845184 |
0.45 |
|
| 2008 |
Giddens AC, Nielsen L, Boshoff HI, Tasdemir D, Perozzo R, Kaiser M, Wang F, Sacchettini JC, Copp BR. ChemInform Abstract: Natural Product Inhibitors of Fatty Acid Biosynthesis: Synthesis of the Marine Microbial Metabolites Pseudopyronines A (Ia) and B (Ib) and Evaluation of Their Antiinfective Activities. Cheminform. 39. DOI: 10.1002/CHIN.200836218 |
0.779 |
|
| 2007 |
Pearce AN, Chia EW, Berridge MV, Clark GR, Harper JL, Larsen L, Maas EW, Page MJ, Perry NB, Webb VL, Copp BR. Anti-inflammatory thiazine alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis. Journal of Natural Products. 70: 936-40. PMID 17497807 DOI: 10.1021/Np060626O |
0.601 |
|
| 2007 |
Copp BR, Pearce AN. Natural product growth inhibitors of Mycobacterium tuberculosis. Natural Product Reports. 24: 278-97. PMID 17389998 DOI: 10.1039/B513520F |
0.616 |
|
| 2007 |
Blunt JW, Copp BR, Hu WP, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 24: 31-86. PMID 17268607 DOI: 10.1039/b603047p |
0.763 |
|
| 2007 |
Pearce AN, Chia EW, Berridge MV, Maas EW, Page MJ, Webb VL, Harper JL, Copp BR. E/Z-rubrolide O, an anti-inflammatory halogenated furanone from the New Zealand ascidian Synoicum n. sp. Journal of Natural Products. 70: 111-3. PMID 17253860 DOI: 10.1021/Np060188L |
0.517 |
|
| 2006 |
Blunt JW, Copp BR, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 23: 26-78. PMID 16453031 DOI: 10.1039/b502792f |
0.761 |
|
| 2006 |
Grkovic T, Kaur B, Webb VL, Copp BR. Semi-synthetic preparation of the rare, cytotoxic, deep-sea sourced sponge metabolites discorhabdins P and U. Bioorganic & Medicinal Chemistry Letters. 16: 1944-6. PMID 16439119 DOI: 10.1016/J.Bmcl.2005.12.081 |
0.714 |
|
| 2006 |
Alfaro AC, Copp BR, Appleton DR, Kelly S, Jeffs AG. Chemical cues promote settlement in larvae of the green-lipped mussel, Perna canaliculus Aquaculture International. 14: 405-412. DOI: 10.1007/S10499-005-9041-Y |
0.665 |
|
| 2005 |
Copp BR, Christiansen HC, Lindsay BS, G Franzblau S. Identification of heteroarylenamines as a new class of antituberculosis lead molecules. Bioorganic & Medicinal Chemistry Letters. 15: 4097-9. PMID 16005211 DOI: 10.1016/J.Bmcl.2005.06.010 |
0.786 |
|
| 2005 |
Antunes EM, Copp BR, Davies-Coleman MT, Samaai T. Pyrroloiminoquinone and related metabolites from marine sponges. Natural Product Reports. 22: 62-72. PMID 15692617 DOI: 10.1039/B407299P |
0.404 |
|
| 2005 |
Blunt JW, Copp BR, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 22: 15-61. PMID 15692616 DOI: 10.1039/b415080p |
0.761 |
|
| 2005 |
Giddens AC, Boshoff HIM, Franzblau SG, Barry CE, Copp BR. Antimycobacterial natural products: Synthesis and preliminary biological evaluation of the oxazole-containing alkaloid texaline Tetrahedron Letters. 46: 7355-7357. DOI: 10.1016/J.Tetlet.2005.08.119 |
0.816 |
|
| 2005 |
Copp BR, Christiansen HC, Lindsay BS, Franzblau SG. Identification of Heteroarylenamines as a New Class of Antituberculosis Lead Molecules. Cheminform. 36. DOI: 10.1002/chin.200551136 |
0.751 |
|
| 2004 |
Marshall KM, Holden JA, Koller A, Kashman Y, Copp BR, Barrows LR. AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex. Anti-Cancer Drugs. 15: 907-13. PMID 15457132 DOI: 10.1097/00001813-200410000-00012 |
0.326 |
|
| 2004 |
Blunt JW, Copp BR, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 21: 1-49. PMID 15039834 DOI: 10.1039/b305250h |
0.761 |
|
| 2004 |
Appleton DR, Page MJ, Lambert G, Copp BR. 1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum. Natural Product Research. 18: 39-42. PMID 14974616 DOI: 10.1080/1057563031000122077 |
0.718 |
|
| 2003 |
Copp BR. Antimycobacterial natural products. Natural Product Reports. 20: 535-57. PMID 14700198 DOI: 10.1039/B212154A |
0.455 |
|
| 2003 |
Copp BR, Kayser O, Brun R, Kiderlen AF. Antiparasitic activity of marine pyridoacridone alkaloids related to the ascididemins. Planta Medica. 69: 527-31. PMID 12865971 DOI: 10.1055/S-2003-40640 |
0.382 |
|
| 2003 |
Blunt JW, Copp BR, Munro MH, Northcote PT, Prinsep MR. Marine natural products. Natural Product Reports. 20: 1-48. PMID 12636082 |
0.768 |
|
| 2003 |
Matsumoto SS, Biggs J, Copp BR, Holden JA, Barrows LR. Mechanism of ascididemin-induced cytotoxicity. Chemical Research in Toxicology. 16: 113-22. PMID 12588181 DOI: 10.1021/Tx025618W |
0.328 |
|
| 2003 |
Pearce A, Appleton DR, Babcock RC, Copp BR. Distomadines A and B, novel 6-hydroxyquinoline alkaloids from the New Zealand ascidian, Pseudodistoma aureum Tetrahedron Letters. 44: 3897-3899. DOI: 10.1016/S0040-4039(03)00831-1 |
0.752 |
|
| 2003 |
Appleton DR, Copp BR. Kottamide E, the first example of a natural product bearing the amino acid 4-amino-1,2-dithiolane-4-carboxylic acid (Adt) Tetrahedron Letters. 44: 8963-8965. DOI: 10.1016/J.Tetlet.2003.10.008 |
0.684 |
|
| 2002 |
Appleton DR, Page MJ, Lambert G, Berridge MV, Copp BR. Kottamides A-D: novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae. The Journal of Organic Chemistry. 67: 5402-4. PMID 12126438 DOI: 10.1021/Jo0201427 |
0.718 |
|
| 2002 |
Appleton DR, Sewell MA, Berridge MV, Copp BR. A new biologically active malyngamide from a New Zealand collection of the sea hare Bursatella leachii. Journal of Natural Products. 65: 630-1. PMID 11975522 DOI: 10.1021/Np010511E |
0.726 |
|
| 2002 |
Appleton DR, Pearce A, Lambert G, Babcock RC, Copp BR. Isodiplamine, cystodytin K and lissoclinidine: novel bioactive alkaloids from the New Zealand ascidian Lissoclinum notti Tetrahedron. 58: 9779-9783. DOI: 10.1016/S0040-4020(02)01296-6 |
0.761 |
|
| 2001 |
Pearce AN, Babcock RC, Lambert G, Copp BR. N2,N2,7-trimethylguanine, a new trimethylated guanine natural product from the New Zealand ascidian, Lissoclinum notti. Natural Product Letters. 15: 237-41. PMID 11833618 DOI: 10.1080/10575630108041287 |
0.486 |
|
| 2001 |
Pearce AN, Babcock RC, Battershill CN, Lambert G, Copp BR. Enantiomeric 1,2,3-trithiane-containing alkaloids and two new 1,3-dithiane alkaloids from New Zealand ascidians. The Journal of Organic Chemistry. 66: 8257-9. PMID 11722237 DOI: 10.1021/Jo010769+ |
0.552 |
|
| 2001 |
Baker L, Copp BR, Rickard CEF. 2′-Amino-5′-bromoacetophenone Acta Crystallographica Section E Structure Reports Online. 57: o540-o541. DOI: 10.1107/S160053680100839X |
0.35 |
|
| 2001 |
Baker L, Copp BR, Rickard CEF. 2′-Amino-3′,5′-dibromoacetophenone Acta Crystallographica Section E Structure Reports Online. 57: o538-o539. DOI: 10.1107/S1600536801008388 |
0.366 |
|
| 2001 |
Appleton DR, Babcock RC, Copp BR. Novel tryptophan-derived dipeptides and bioactive metabolites from the sea hare Aplysia dactylomela Tetrahedron. 57: 10181-10189. DOI: 10.1016/S0040-4020(01)01044-4 |
0.751 |
|
| 2000 |
Copp BR, Wassvik CM, Lambert G, Page MJ. Isolation and characterization of the new purine 1,3, 7-trimethylisoguanine from the New Zealand ascidian Pseudodistoma cereum. Journal of Natural Products. 63: 1168-9. PMID 10978221 DOI: 10.1021/Np000172+ |
0.398 |
|
| 2000 |
Copp BR, Lindsay BS, Oliver AG, Rickard CE. 11-methylpyrido[2,3-b]acridine-5,12-dione. Acta Crystallographica. Section C, Crystal Structure Communications. 56: 102-3. PMID 10710687 DOI: 10.1107/S0108270199013578 |
0.776 |
|
| 2000 |
Lindsay BS, Christiansen HC, Copp BR. Structural Studies of Cytotoxic Marine Alkaloids: Synthesis of Novel Ring-E Analogues of Ascididemin and their in vitro and in vivo Biological Evaluation Tetrahedron. 56: 497-505. DOI: 10.1016/S0040-4020(99)01038-8 |
0.819 |
|
| 1999 |
Lindsay BS, Battershill CN, Copp BR. 1,3-Dimethylguanine, a new purine from the new zealand ascidian botrylloides leachi Journal of Natural Products. 62: 638-9. PMID 10217731 DOI: 10.1021/Np980477C |
0.797 |
|
| 1999 |
Copp BR, Hansen RP, Appleton DR, Lindsay BS, Squire CJ, Clark GR, Rickard CEF. A Convenient New Route to 4-Substituted Benzo[de][3,6]Phenanthrolin-6(6H)-Ones: Important Intermediates in the Synthesis of Ring-A Analogues of the Cytotoxic Marine Alkaloid Ascididemin Synthetic Communications. 29: 2665-2676. DOI: 10.1080/00397919908086428 |
0.801 |
|
| 1998 |
Copp BR, Fairchild CR, Cornell L, Casazza AM, Robinson S, Ireland CM. Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent Journal of Medicinal Chemistry. 41: 3909-3911. PMID 9748366 DOI: 10.1021/Jm980294N |
0.543 |
|
| 1998 |
Lindsay BS, Battershill CN, Copp BR. Isolation of 2-(3'-bromo-4'-hydroxyphenol)ethanamine from the New Zealand ascidian Cnemidocarpa bicornuta. Journal of Natural Products. 61: 857-8. PMID 9644087 DOI: 10.1021/Np980052Q |
0.806 |
|
| 1998 |
Lindsay BS, Oliver AG, Rickard CEF, Copp BR. Crystal structure of the cytotoxic marine alkaloid 2-bromoleptoclinidinone Journal of Chemical Crystallography. 28: 645-648. DOI: 10.1023/A:1022421328245 |
0.769 |
|
| 1998 |
De Guzman FS, Copp BR, Mayne CL, Conception GP, Mangalindan GC, Barrows LR, Ireland CM. Bolinaquinone: A novel cytotoxic sesquiterpene hydroxyquinone from a Philippine Dysidea sponge Journal of Organic Chemistry. 63: 8042-8044. DOI: 10.1021/Jo981037T |
0.612 |
|
| 1998 |
Copp BR, Jompa J, Tahir A, Ireland CM. Styelsamines A-D: New tetracyclic pyridoacridine alkaloids from the indonesian ascidian eusynstyela latericius Journal of Organic Chemistry. 63: 8024-8026. DOI: 10.1021/Jo980905J |
0.557 |
|
| 1997 |
Lindsay BS, Pearce AN, Copp BR. Efficient and Convenient Pyridine Ring-E Formation of the Cytotoxic Marine Alkaloid Ascididemin and Related Analogues. Synthetic Communications. 27: 2587-2592. DOI: 10.1080/00397919708004128 |
0.792 |
|
| 1995 |
Ainsworth AM, Chicarelli-Robinson MI, Copp BR, Fauth U, Hylands PJ, Holloway JA, Latif M, O'Beirne GB, Porter N, Renno DV. Xenovulene A, a novel GABA-benzodiazepine receptor binding compound produced by Acremonium strictum. The Journal of Antibiotics. 48: 568-73. PMID 7649852 DOI: 10.7164/Antibiotics.48.568 |
0.311 |
|
| 1995 |
Lindsay BS, Barrows LR, Copp BR. Structural requirements for biological activity of the marine alkaloid ascididemin Bioorganic and Medicinal Chemistry Letters. 5: 739-742. DOI: 10.1016/0960-894X(95)00106-4 |
0.796 |
|
| 1994 |
Copp BR, Fulton KF, Perry NB, Blunt JW, Munro MHG. Natural and Synthetic Derivatives of Discorhabdin C, a Cytotoxic Pigment from the New Zealand Sponge Latrunculia cf. bocagei The Journal of Organic Chemistry. 59: 8233-8238. DOI: 10.1021/Jo00105A047 |
0.589 |
|
| 1993 |
Barrows LR, Radisky DC, Copp BR, Swaffar DS, Kramer RA, Warters RL, Ireland CM. Makaluvamines, marine natural products, are active anti-cancer agents and DNA topo II inhibitors Anti-Cancer Drug Design. 8: 333-347. PMID 8251041 |
0.5 |
|
| 1993 |
Radisky DC, Radisky ES, Barrows LR, Copp BR, Kramer RA, Ireland CM. Novel cytotoxic topoisomerase II inhibiting pyrroloiminoquinones from Fijian sponges of the genus Zyzzya Journal of the American Chemical Society. 115: 1632-1638. DOI: 10.1021/Ja00058A003 |
0.651 |
|
| 1992 |
Copp BR, Ireland CM, Barrows LR. Psammaplysin C: A new cytotoxic dibromotyrosine-derived metabolite from the marine sponge Druinella (=Psammaplysilla) purpurea Journal of Natural Products. 55: 822-823. PMID 1522422 DOI: 10.1021/Np50084A021 |
0.639 |
|
| 1991 |
Copp BR, Ireland CM, Barrows LR. Wakayin: A novel cytotoxic pyrroloiminoquinone alkaloid from the ascidian Clavelina species Journal of Organic Chemistry. 56: 4596-4597. DOI: 10.1021/Jo00015A005 |
0.553 |
|
| 1989 |
Copp BR, Blunt JW, Munro MH, Pannell LK. A biologically active 1,2,3-trithiane derivative from the New Zealand ascidain Aplidium sp. D. Tetrahedron Letters. 30: 3703-3706. DOI: 10.1016/S0040-4039(01)80488-3 |
0.732 |
|
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