Kevin S. Orwig, Ph.D. - Publications
Affiliations: | 2006 | Medical University of South Carolina, Charleston, SC, United States |
Area:
PharmacologyYear | Citation | Score | |||
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2010 | Lundquist IV JT, Orwig KS, Dix TA. ChemInform Abstract: Synthesis of Ethylene-Bridged (Nδ to Nω) Analogues of Arginine. Cheminform. 31: no-no. DOI: 10.1002/chin.200011200 | 0.562 | |||
2009 | Orwig KS, Lassetter MR, Hadden MK, Dix TA. Comparison of N-terminal modifications on neurotensin(8-13) analogues correlates peptide stability but not binding affinity with in vivo efficacy. Journal of Medicinal Chemistry. 52: 1803-13. PMID 19290594 DOI: 10.1021/Jm801072V | 0.726 | |||
2005 | Hadden MK, Orwig KS, Kokko KP, Mazella J, Dix TA. Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8-13) analogues containing non-natural arginine and lysine residues. Neuropharmacology. 49: 1149-59. PMID 16095636 DOI: 10.1016/J.Neuropharm.2005.06.010 | 0.643 | |||
2005 | Kokko KP, Hadden MK, Price KL, Orwig KS, See RE, Dix TA. In vivo behavioral effects of stable, receptor-selective neurotensin[8-13] analogues that cross the blood-brain barrier. Neuropharmacology. 48: 417-25. PMID 15721174 DOI: 10.1016/J.Neuropharm.2004.10.008 | 0.648 | |||
2005 | Orwig KS, Dix TA. Synthesis of Cα methylated carboxylic acids: isosteres of arginine and lysine for use as N-terminal capping residues in polypeptides Tetrahedron Letters. 46: 7007-7009. DOI: 10.1016/J.Tetlet.2005.08.056 | 0.637 | |||
2003 | Kokko KP, Hadden MK, Orwig KS, Mazella J, Dix TA. In vitro analysis of stable, receptor-selective neurotensin[8-13] analogues. Journal of Medicinal Chemistry. 46: 4141-8. PMID 12954066 DOI: 10.1021/Jm0300633 | 0.649 | |||
2002 | Kennedy KJ, Orwig KS, Dix TA, Christopher J, Jaffa AA. Synthesis and analysis of potent, more lipophilic derivatives of the bradykinin B2 receptor antagonist peptide Hoe 140. The Journal of Peptide Research : Official Journal of the American Peptide Society. 59: 139-48. PMID 11972749 DOI: 10.1034/J.1399-3011.2002.1O987.X | 0.721 | |||
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