Elizabeth Gibbs, Ph.D. - Publications

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Gibbs EM, Davidson AE, Telfer WR, Feldman EL, Dowling JJ. The myopathy-causing mutation DNM2-S619L leads to defective tubulation in vitro and in developing zebrafish. Disease Models & Mechanisms. 7: 157-61. PMID 24135484 DOI: 10.1242/dmm.012286  0.68
2013 Horstick EJ, Gibbs EM, Li X, Davidson AE, Dowling JJ. Analysis of embryonic and larval zebrafish skeletal myofibers from dissociated preparations. Journal of Visualized Experiments : Jove. e50259. PMID 24300240 DOI: 10.3791/50259  0.68
2013 Gibbs EM, Horstick EJ, Dowling JJ. Swimming into prominence: the zebrafish as a valuable tool for studying human myopathies and muscular dystrophies. The Febs Journal. 280: 4187-97. PMID 23809187 DOI: 10.1111/febs.12412  0.68
2013 Maciejewski BS, LaPerle JL, Chen D, Ghosh A, Zavadoski WJ, McDonald TS, Manion TB, Mather D, Patterson TA, Hanna M, Watkins S, Gibbs EM, Calle RA, Steppan CM. Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G958-69. PMID 23558010 DOI: 10.1152/ajpgi.00384.2012  0.68
2013 Gibbs EM, Davidson AE, Trickey-Glassman A, Backus C, Hong Y, Sakowski SA, Dowling JJ, Feldman EL. Two dynamin-2 genes are required for normal zebrafish development. Plos One. 8: e55888. PMID 23418470 DOI: 10.1371/journal.pone.0055888  0.68
2013 Gibbs EM, Clarke NF, Rose K, Oates EC, Webster R, Feldman EL, Dowling JJ. Neuromuscular junction abnormalities in DNM2-related centronuclear myopathy. Journal of Molecular Medicine (Berlin, Germany). 91: 727-37. PMID 23338057 DOI: 10.1007/s00109-013-0994-4  0.68
2012 Nance JR, Dowling JJ, Gibbs EM, Bönnemann CG. Congenital myopathies: an update. Current Neurology and Neuroscience Reports. 12: 165-74. PMID 22392505 DOI: 10.1007/s11910-012-0255-x  0.68
2011 Dow RL, Li JC, Pence MP, Gibbs EM, LaPerle JL, Litchfield J, Piotrowski DW, Munchhof MJ, Manion TB, Zavadoski WJ, Walker GS, McPherson RK, Tapley S, Sugarman E, Guzman-Perez A, et al. Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1. Acs Medicinal Chemistry Letters. 2: 407-12. PMID 24900321 DOI: 10.1021/ml200051p  0.68
2011 Enayetallah AE, Ziemek D, Leininger MT, Randhawa R, Yang J, Manion TB, Mather DE, Zavadoski WJ, Kuhn M, Treadway JL, des Etages SA, Gibbs EM, Greene N, Steppan CM. Modeling the mechanism of action of a DGAT1 inhibitor using a causal reasoning platform. Plos One. 6: e27009. PMID 22073239 DOI: 10.1371/journal.pone.0027009  0.68
2011 Withers GS, Wallace CS, Gibbs EM, Emery IR, Applegate ML. Synapses on demand require dendrites at the ready: how defining stages of dendritic development in vitro could inform studies of behaviorally driven information storage in the brain. Developmental Psychobiology. 53: 443-55. PMID 21678392 DOI: 10.1002/dev.20560  0.68
2010 Gibbs EM, Feldman EL, Dowling JJ. The role of MTMR14 in autophagy and in muscle disease. Autophagy. 6: 819-20. PMID 20595810 DOI: 10.4161/auto.6.6.12624  0.68
2010 Deshmukh AS, Long YC, de Castro Barbosa T, Karlsson HK, Glund S, Zavadoski WJ, Gibbs EM, Koistinen HA, Wallberg-Henriksson H, Zierath JR. Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle. Diabetologia. 53: 1142-50. PMID 20349036 DOI: 10.1007/s00125-010-1716-x  0.68
2010 Kumari R, Willing LB, Patel SD, Krady JK, Zavadoski WJ, Gibbs EM, Vannucci SJ, Simpson IA. The PPAR-gamma agonist, darglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 352-60. PMID 19861974 DOI: 10.1038/jcbfm.2009.221  0.68
2009 Dowling JJ, Vreede AP, Low SE, Gibbs EM, Kuwada JY, Bonnemann CG, Feldman EL. Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy. Plos Genetics. 5: e1000372. PMID 19197364 DOI: 10.1371/journal.pgen.1000372  0.68
2008 Dowling JJ, Gibbs EM, Feldman EL. Membrane traffic and muscle: lessons from human disease. Traffic (Copenhagen, Denmark). 9: 1035-43. PMID 18266915 DOI: 10.1111/j.1600-0854.2008.00716.x  0.68
2008 Dowling JJ, Gibbs E, Russell M, Goldman D, Minarcik J, Golden JA, Feldman EL. Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function. Circulation Research. 102: 423-31. PMID 18174465 DOI: 10.1161/CIRCRESAHA.107.161489  0.68
2007 Houseknecht KL, Robertson AS, Zavadoski W, Gibbs EM, Johnson DE, Rollema H. Acute effects of atypical antipsychotics on whole-body insulin resistance in rats: implications for adverse metabolic effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 289-97. PMID 17035934 DOI: 10.1038/sj.npp.1301209  0.68
2006 Yu LJ, Chen Y, Treadway JL, McPherson RK, McCoid SC, Gibbs EM, Hoover DJ. Establishment of correlation between in vitro enzyme binding potency and in vivo pharmacological activity: application to liver glycogen phosphorylase a inhibitors. The Journal of Pharmacology and Experimental Therapeutics. 317: 1230-7. PMID 16537796 DOI: 10.1124/jpet.105.100545  0.68
2005 Johnson DE, Yamazaki H, Ward KM, Schmidt AW, Lebel WS, Treadway JL, Gibbs EM, Zawalich WS, Rollema H. Inhibitory effects of antipsychotics on carbachol-enhanced insulin secretion from perifused rat islets: role of muscarinic antagonism in antipsychotic-induced diabetes and hyperglycemia. Diabetes. 54: 1552-8. PMID 15855345 DOI: 10.2337/diabetes.54.5.1552  0.68
2005 Ercan-Fang N, Taylor MR, Treadway JL, Levy CB, Genereux PE, Gibbs EM, Rath VL, Kwon Y, Gannon MC, Nuttall FQ. Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors. American Journal of Physiology. Endocrinology and Metabolism. 289: E366-72. PMID 15797986 DOI: 10.1152/ajpendo.00264.2004  0.68
2005 Harwood HJ, Petras SF, Hoover DJ, Mankowski DC, Soliman VF, Sugarman ED, Hulin B, Kwon Y, Gibbs EM, Mayne JT, Treadway JL. Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase. Journal of Lipid Research. 46: 547-63. PMID 15604516 DOI: 10.1194/jlr.M400436-JLR200  0.68
2005 Wright SW, Rath VL, Genereux PE, Hageman DL, Levy CB, McClure LD, McCoid SC, McPherson RK, Schelhorn TM, Wilder DE, Zavadoski WJ, Gibbs EM, Treadway JL. 5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization. Bioorganic & Medicinal Chemistry Letters. 15: 459-65. PMID 15603973 DOI: 10.1016/j.bmcl.2004.10.048  0.68
2002 Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL. Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase. Chemistry & Biology. 9: 915-24. PMID 12204691 DOI: 10.1016/S1074-5521(02)00186-2  0.68
2001 Brozinick JT, McCoid SC, Reynolds TH, Nardone NA, Hargrove DM, Stevenson RW, Cushman SW, Gibbs EM. GLUT4 overexpression in db/db mice dose-dependently ameliorates diabetes but is not a lifelong cure. Diabetes. 50: 593-600. PMID 11246879  0.68
2001 Belke DD, Larsen TS, Gibbs EM, Severson DL. Glucose metabolism in perfused mouse hearts overexpressing human GLUT-4 glucose transporter. American Journal of Physiology. Endocrinology and Metabolism. 280: E420-7. PMID 11171596  0.68
2000 Belke DD, Larsen TS, Gibbs EM, Severson DL. Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice. American Journal of Physiology. Endocrinology and Metabolism. 279: E1104-13. PMID 11052966  0.68
2000 Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ. Human liver glycogen phosphorylase inhibitors bind at a new allosteric site. Chemistry & Biology. 7: 677-82. PMID 10980448 DOI: 10.1016/S1074-5521(00)00004-1  0.68
1999 Ishizuka T, Klepcyk P, Liu S, Panko L, Liu S, Gibbs EM, Friedman JE. Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice. Diabetes. 48: 1061-9. PMID 10331411 DOI: 10.2337/diabetes.48.5.1061  0.68
1999 Etgen GJ, Zavadoski WJ, Holman GD, Gibbs EM. Insulin-sensitive regulation of glucose transport and GLUT4 translocation in skeletal muscle of GLUT1 transgenic mice. The Biochemical Journal. 337: 51-7. PMID 9854024 DOI: 10.1042/0264-6021:3370051  0.68
1998 Hoover DJ, Lefkowitz-Snow S, Burgess-Henry JL, Martin WH, Armento SJ, Stock IA, McPherson RK, Genereux PE, Gibbs EM, Treadway JL. Indole-2-carboxamide inhibitors of human liver glycogen phosphorylase. Journal of Medicinal Chemistry. 41: 2934-8. PMID 9685232 DOI: 10.1021/jm980264k  0.68
1998 Stevenson RW, Kreutter DK, Andrews KM, Genereux PE, Gibbs EM. Possibility of distinct insulin-signaling pathways beyond phosphatidylinositol 3-kinase-mediating glucose transport and lipogenesis. Diabetes. 47: 179-85. PMID 9519710  0.68
1997 Etgen GJ, Fryburg DA, Gibbs EM. Nitric oxide stimulates skeletal muscle glucose transport through a calcium/contraction- and phosphatidylinositol-3-kinase-independent pathway. Diabetes. 46: 1915-9. PMID 9356048  0.68
1997 Vannucci SJ, Gibbs EM, Simpson IA. Glucose utilization and glucose transporter proteins GLUT-1 and GLUT-3 in brains of diabetic (db/db) mice. The American Journal of Physiology. 272: E267-74. PMID 9124334  0.68
1997 Brozinick JT, McCoid SC, Reynolds TH, Wilson CM, Stevenson RW, Cushman SW, Gibbs EM. Regulation of cell surface GLUT4 in skeletal muscle of transgenic mice. The Biochemical Journal. 321: 75-81. PMID 9003403  0.68
1996 Sarges R, Hank RF, Blake JF, Bordner J, Bussolotti DL, Hargrove DM, Treadway JL, Gibbs EM. Glucose transport-enhancing and hypoglycemic activity of 2-methyl-2-phenoxy-3-phenylpropanoic acids. Journal of Medicinal Chemistry. 39: 4783-803. PMID 8941393 DOI: 10.1021/jm950364f  0.68
1996 Evans LA, Genereux PE, Gibbs EM, Sutton SC. Predicting injection site muscle damage. III: Evaluation of intramuscular formulations in the L6 cell model. Pharmaceutical Research. 13: 1585-7. PMID 8899856 DOI: 10.1023/A:1016004318459  0.68
1996 Hulin B, Newton LS, Lewis DM, Genereux PE, Gibbs EM, Clark DA. Hypoglycemic activity of a series of alpha-alkylthio and alpha-alkoxy carboxylic acids related to ciglitazone. Journal of Medicinal Chemistry. 39: 3897-907. PMID 8831756 DOI: 10.1021/jm960230h  0.68
1996 Brozinick JT, Yaspelkis BB, Wilson CM, Grant KE, Gibbs EM, Cushman SW, Ivy JL. Glucose transport and GLUT4 protein distribution in skeletal muscle of GLUT4 transgenic mice. The Biochemical Journal. 313: 133-40. PMID 8546674  0.68
1996 Stevenson RW, McPherson RK, Persson LM, Genereux PE, Swick AG, Spitzer J, Herbst JJ, Andrews KM, Kreutter DK, Gibbs EM. The antihyperglycemic agent englitazone prevents the defect in glucose transport in rats fed a high-fat diet. Diabetes. 45: 60-6. PMID 8522061  0.68
1995 Gibbs EM, Stock JL, McCoid SC, Stukenbrok HA, Pessin JE, Stevenson RW, Milici AJ, McNeish JD. Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4). The Journal of Clinical Investigation. 95: 1512-8. PMID 7706456 DOI: 10.1172/JCI117823  0.68
1995 Herbst JJ, Andrews GC, Contillo LG, Singleton DH, Genereux PE, Gibbs EM, Lienhard GE. Effect of the activation of phosphatidylinositol 3-kinase by a thiophosphotyrosine peptide on glucose transport in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 270: 26000-5. PMID 7592791 DOI: 10.1074/jbc.270.43.26000  0.68
1994 Treadway JL, Hargrove DM, Nardone NA, McPherson RK, Russo JF, Milici AJ, Stukenbrok HA, Gibbs EM, Stevenson RW, Pessin JE. Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT4 gene. The Journal of Biological Chemistry. 269: 29956-61. PMID 7961994  0.68
1994 Gould GW, Jess TJ, Andrews GC, Herbst JJ, Plevin RJ, Gibbs EM. Evidence for a role of phosphatidylinositol 3-kinase in the regulation of glucose transport in Xenopus oocytes. The Journal of Biological Chemistry. 269: 26622-5. PMID 7929393  0.68
1994 Herbst JJ, Andrews G, Contillo L, Lamphere L, Gardner J, Lienhard GE, Gibbs EM. Potent activation of phosphatidylinositol 3′-kinase by simple phosphotyrosine peptides derived from insulin receptor substrate 1 containing two YMXM motifs for binding SH2 domains Biochemistry. 33: 9376-9381.  0.68
1993 Marshall BA, Ren JM, Johnson DW, Gibbs EM, Lillquist JS, Soeller WC, Holloszy JO, Mueckler M. Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle. The Journal of Biological Chemistry. 268: 18442-5. PMID 8360145  0.68
1993 Liu ML, Gibbs EM, McCoid SC, Milici AJ, Stukenbrok HA, McPherson RK, Treadway JL, Pessin JE. Transgenic mice expressing the human GLUT4/muscle-fat facilitative glucose transporter protein exhibit efficient glycemic control. Proceedings of the National Academy of Sciences of the United States of America. 90: 11346-50. PMID 8248251  0.68
1993 Hulin B, Lau CL, Gibbs EM. Synthesis of a biotin conjugate of darglitazone, a new antidiabetic agent. A general protocol for the reversible biotinylation of ketones Bioorganic and Medicinal Chemistry Letters. 3: 703-706. DOI: 10.1016/S0960-894X(01)81258-0  0.68
1992 Gould GW, Brant AM, Kahn BB, Shepherd PR, McCoid SC, Gibbs EM. Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice. Diabetologia. 35: 304-9. PMID 1516757 DOI: 10.1007/BF00401196  0.68
1992 Brant AM, McCoid S, Thomas HM, Baldwin SA, Davies A, Parker JC, Gibbs EM, Gould GW. Analysis of the glucose transporter content of islet cell lines: implications for glucose-stimulated insulin release. Cellular Signalling. 4: 641-50. PMID 1489658 DOI: 10.1016/0898-6568(92)90045-A  0.68
1992 Brant AM, Gibbs EM, Gould GW, Thomas HM. Immunological identification of five members of the human facilitative glucose transporter family. Biochemical Society Transactions. 20: 236S. PMID 1426534  0.68
1992 Brant AM, Gibbs EM, Gould GW. Examination of the glycosidation state of five members of the human facilitative glucose transporter family. Biochemical Society Transactions. 20: 235S. PMID 1426533  0.68
1992 Shepherd PR, Gould GW, Colville CA, McCoid SC, Gibbs EM, Kahn BB. Distribution of GLUT3 glucose transporter protein in human tissues. Biochemical and Biophysical Research Communications. 188: 149-54. PMID 1417839 DOI: 10.1016/0006-291X(92)92362-2  0.68
1992 Shepherd PR, Gibbs EM, Wesslau C, Gould GW, Kahn BB. Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation. Diabetes. 41: 1360-5. PMID 1397712  0.68
1991 Gibbs EM, Calderhead DM, Holman GD, Gould GW. Phorbol ester only partially mimics the effects of insulin on glucose transport and glucose-transporter distribution in 3T3-L1 adipocytes. The Biochemical Journal. 275: 145-50. PMID 2018470  0.68
1990 Kreutter DK, Andrews KM, Gibbs EM, Hutson NJ, Stevenson RW. Insulinlike activity of new antidiabetic agent CP 68722 in 3T3-L1 adipocytes. Diabetes. 39: 1414-9. PMID 2227113  0.68
1990 Stevenson RW, Hutson NJ, Krupp MN, Volkmann RA, Holland GF, Eggler JF, Clark DA, McPherson RK, Hall KL, Danbury BH, Gibbs EM, Kreutter DK. Actions of novel antidiabetic agent englitazone in hyperglycemic hyperinsulinemic ob/ob mice Diabetes. 39: 1218-1227. PMID 2210074  0.68
1989 Frost SC, Lane MD, Gibbs EM. Effect of phenylarsine oxide on fluid phase endocytosis: further evidence for activation of the glucose transporter. Journal of Cellular Physiology. 141: 467-74. PMID 2687296 DOI: 10.1002/jcp.1041410304  0.68
1989 Gould GW, Lienhard GE, Tanner LI, Gibbs EM. Phenylarsine oxide stimulates hexose transport in 3T3-L1 adipocytes by a mechanism other than an increase in surface transporters. Archives of Biochemistry and Biophysics. 268: 264-75. PMID 2643384 DOI: 10.1016/0003-9861(89)90588-2  0.68
1989 Gould GW, Derechin V, James DE, Tordjman K, Ahern S, Gibbs EM, Lienhard GE, Mueckler M. Insulin-stimulated translocation of the HepG2/erythrocyte-type glucose transporter expressed in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 264: 2180-4. PMID 2536700  0.68
1988 Blok J, Gibbs EM, Lienhard GE, Slot JW, Geuze HJ. Insulin-induced translocation of glucose transporters from post-Golgi compartments to the plasma membrane of 3T3-L1 adipocytes. The Journal of Cell Biology. 106: 69-76. PMID 3276714  0.68
1988 Gibbs EM, Lienhard GE, Gould GW. Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport. Biochemistry. 27: 6681-5. PMID 3058203  0.68
1988 Witters LA, Watts TD, Gould GW, Lienhard GE, Gibbs EM. Regulation of protein phosphorylation by insulin and an insulinomimetic oligosaccharide in 3T3-L1 adipocytes and Fao hepatoma cells. Biochemical and Biophysical Research Communications. 153: 992-8. PMID 2839176 DOI: 10.1016/S0006-291X(88)81326-3  0.68
1987 Allard WJ, Gibbs EM, Witters LA, Lienhard GE. The glucose transporter in human fibroblasts is phosphorylated in response to phorbol ester but not in response to growth factors. Biochimica Et Biophysica Acta. 929: 288-95. PMID 3300786 DOI: 10.1016/0167-4889(87)90255-2  0.68
1986 Gibbs EM, Allard WJ, Lienhard GE. The glucose transporter in 3T3-L1 adipocytes is phosphorylated in response to phorbol ester but not in response to insulin. The Journal of Biological Chemistry. 261: 16597-603. PMID 3536929  0.68
1986 Gibbs EM, Lienhard GE, Appleman JR, Lane MD, Frost SC. Insulin stimulates fluid-phase endocytosis and exocytosis in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 261: 3944-51. PMID 3512562  0.68
1985 Gibbs EM, Lienhard GE, Lane MD, Frost SC. Kinetics of fluid-phase exocytosis in 3T3-L1 adipocytes: Stimulation by insulin Federation Proceedings. 44: No. 8147.  0.68
1984 Gibbs EM, Lienhard GE. Fluid-phase endocytosis by isolated rat adipocytes. Journal of Cellular Physiology. 121: 569-75. PMID 6389574 DOI: 10.1002/jcp.1041210316  0.68
1982 Gibbs EM, Hosang M, Reber BF, Semenza G, Diedrich DF. 4-Azidophlorizin, a high affinity probe and photoaffinity label for the glucose transporter in brush border membranes. Biochimica Et Biophysica Acta. 688: 547-56. PMID 7201853 DOI: 10.1016/0005-2736(82)90366-2  0.68
1981 Fannin FF, Evans JO, Gibbs EM, Diedrich DF. Phloretinyl-3'-benzylazide: a high affinity probe for the sugar transporter in human erythrocytes. I. Hexose transport inhibition and photolabeling of mutarotase. Biochimica Et Biophysica Acta. 649: 189-201. PMID 7198487 DOI: 10.1016/0005-2736(81)90406-5  0.68
1981 Gibbs EM, Hosang M, Diedrich DF. Inhibition of D-glucose transport and phlorizin binding by a 4-azide derivative of phlorizin Federation Proceedings. 40: 775.  0.68
1980 Diedrich DF, Gibbs EM, Hosang M. 4-Azidophlorizin (4-AzPHZ), a potential photoaffinity label for the renal D-glucose transporter Pharmacologist. 22: 223.  0.68
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