| Year |
Citation |
Score |
| 2019 |
Coltart DM, Uddin N, Knight J, Rastelli E, Soubra-Ghaoui C, Albright T, Wu CH, Wu J. On the Mechanism of the Asymmetric Aldol Addition of Chiral N-Amino Cyclic Carbamate Hydrazones: Evidence of Non-Curtin-Hammett Behavior. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31650641 DOI: 10.1002/Chem.201902388 |
0.813 |
|
| 2019 |
Aderibigbe SO, Coltart DM. Synthesis of 1,3-Diketones and β-Keto Thioesters via Soft Enolization. The Journal of Organic Chemistry. 84: 9770-9777. PMID 31333029 DOI: 10.1021/Acs.Joc.9B00397 |
0.409 |
|
| 2019 |
Ferguson MW, Gerak CAN, Chow CCT, Rastelli EJ, Elmore KE, Stahl F, Hosseini-Farahabadi S, Baradaran-Heravi A, Coltart DM, Roberge M. The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. Plos One. 14: e0216423. PMID 31120902 DOI: 10.1371/Journal.Pone.0216423 |
0.726 |
|
| 2018 |
Huynh U, McDonald SL, Lim D, Uddin MN, Wengryniuk SE, Dey S, Coltart DM. Formation, Alkylation and Hydrolysis of Chiral Nonracemic N-Amino Cyclic Carbamate Hydrazones: An Approach to the Enantioselective α-Alkylation of Ketones. The Journal of Organic Chemistry. PMID 30200759 DOI: 10.1021/Acs.Joc.8B00655 |
0.83 |
|
| 2018 |
Uddin MN, Tarsis EM, Wu CH, Wu JI, Coltart DM. A Mismatch-Free Strategy for the Diastereoselective α,α-Bisalkylation of Chiral Nonracemic Methyl Ketones. Organic Letters. PMID 29897766 DOI: 10.1021/Acs.Orglett.8B01146 |
0.829 |
|
| 2018 |
Rastelli EJ, Bolinger AA, Coltart DM. Stereodivergent Synthesis of β,γ-Fused Bicyclic γ-Lactones via a Multicomponent Ring-Expansion Cascade Chem. 4: 2228-2238. DOI: 10.1016/J.Chempr.2018.08.007 |
0.831 |
|
| 2017 |
Alfie RJ, Truong N, Yost JM, Coltart DM. A kinetically controlled direct aldol addition of α-chloro thioesters via soft enolization Tetrahedron Letters. 58: 185-189. DOI: 10.1016/J.Tetlet.2016.11.010 |
0.8 |
|
| 2017 |
Huynh U, Uddin MN, Wengryniuk SE, McDonald SL, Coltart DM. On the regioselectivity and diastereoselectivity of ACC hydrazone alkylation Tetrahedron. 73: 432-436. DOI: 10.1016/J.Tet.2016.11.064 |
0.783 |
|
| 2016 |
Rastelli EJ, Truong NT, Coltart DM. Asymmetric Induction in Hydroacylation by Cooperative Iminium Ion-Transition-Metal Catalysis. Organic Letters. PMID 27767317 DOI: 10.1021/Acs.Orglett.6B02825 |
0.778 |
|
| 2016 |
Rastelli EJ, Coltart DM. Asymmetric Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride. The Journal of Organic Chemistry. PMID 27657347 DOI: 10.1021/Acs.Joc.6B01476 |
0.814 |
|
| 2016 |
Truong N, Sauer SJ, Seraphin-Hatcher C, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of α-iodo thioesters. Organic & Biomolecular Chemistry. PMID 27492274 DOI: 10.1039/C6Ob01244B |
0.777 |
|
| 2016 |
Huynh U, Uddin MN, Wengryniuk SE, McDonald SL, Coltart DM. A simple and efficient approach to the N-amination of oxazolidinones using monochloroamine Tetrahedron Letters. 57: 4799-4802. DOI: 10.1016/J.Tetlet.2016.09.034 |
0.763 |
|
| 2015 |
Uteuliyev MM, Nguyen TT, Coltart DM. Diastereoselective addition of Grignard reagents to α-epoxy N-sulfonyl hydrazones. Nature Chemistry. 7: 1024-1027. PMID 26587719 DOI: 10.1038/Nchem.2364 |
0.52 |
|
| 2015 |
Rastelli EJ, Coltart DM. A Concise and Highly Enantioselective Total Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride: Definitive Absolute Stereochemical Assignment of the Mefloquines. Angewandte Chemie (International Ed. in English). PMID 26422780 DOI: 10.1002/Anie.201507304 |
0.809 |
|
| 2015 |
Dey S, Wengryniuk SE, Tarsis EM, Robertson BD, Zhou G, Coltart DM. A formal asymmetric synthesis of apratoxin D via advanced-stage asymmetric ACC α,α-bisalkylation of a chiral nonracemic ketone Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2015.04.022 |
0.798 |
|
| 2015 |
Garnsey MR, Uteuliyev MM, Coltart DM. Asymmetric synthesis of structural analogues of (+)-clusianone via enantioselective ACC alkylation Tetrahedron Letters. 56: 3183-3185. DOI: 10.1016/J.Tetlet.2015.01.012 |
0.799 |
|
| 2015 |
Tarsis EM, Rastelli EJ, Wengryniuk SE, Coltart DM. The apratoxin marine natural products: Isolation, structure determination, and asymmetric total synthesis Tetrahedron. 71: 5029-5044. DOI: 10.1016/J.Tet.2015.05.047 |
0.756 |
|
| 2013 |
Knight JD, Coltart DM. Asymmetric anti-aldol addition of achiral ketones via chiral N-amino cyclic carbamate hydrazones. Chemical Communications (Cambridge, England). 49: 7495-7. PMID 23873079 DOI: 10.1039/C3Cc44716B |
0.505 |
|
| 2013 |
Knight JD, Coltart DM. Expanding the scope of the asymmetric anti-aldol addition of chiral N-amino cyclic carbamate hydrazones Tetrahedron Letters. 54: 5470-5472. DOI: 10.1016/J.Tetlet.2013.07.140 |
0.528 |
|
| 2012 |
Robertson BD, Wengryniuk SE, Coltart DM. Asymmetric total synthesis of apratoxin D. Organic Letters. 14: 5192-5. PMID 23057680 DOI: 10.1021/Ol302309C |
0.794 |
|
| 2011 |
Hatcher JM, Kohler MC, Coltart DM. Catalytic asymmetric addition of thiols to nitrosoalkenes leading to chiral non-racemic α-sulfenyl ketones. Organic Letters. 13: 3810-3. PMID 21714489 DOI: 10.1021/Ol2012633 |
0.835 |
|
| 2011 |
Knight JD, Sauer SJ, Coltart DM. Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones. Organic Letters. 13: 3118-21. PMID 21615091 DOI: 10.1021/Ol2010193 |
0.781 |
|
| 2011 |
Wengryniuk SE, Lim D, Coltart DM. Regioselective asymmetric α,α-bisalkylation of ketones via complex-induced syn-deprotonation of chiral N-amino cyclic carbamate hydrazones. Journal of the American Chemical Society. 133: 8714-20. PMID 21510644 DOI: 10.1021/Ja202267K |
0.806 |
|
| 2011 |
Garnsey MR, Matous JA, Kwiek JJ, Coltart DM. Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity. Bioorganic & Medicinal Chemistry Letters. 21: 2406-9. PMID 21414776 DOI: 10.1016/J.Bmcl.2011.02.074 |
0.743 |
|
| 2011 |
Yost JM, Alfie RJ, Tarsis EM, Chong I, Coltart DM. Direct carbon-carbon bond formation via soft enolization: aldol addition of α-halogenated thioesters. Chemical Communications (Cambridge, England). 47: 571-2. PMID 20963247 DOI: 10.1039/C0Cc02345K |
0.792 |
|
| 2010 |
Krenske EH, Houk KN, Lim D, Wengryniuk SE, Coltart DM. Origins of stereoselectivity in the α-alkylation of chiral hydrazones. The Journal of Organic Chemistry. 75: 8578-84. PMID 21070023 DOI: 10.1021/Jo1019877 |
0.801 |
|
| 2010 |
Garnsey MR, Lim D, Yost JM, Coltart DM. Development of a strategy for the asymmetric synthesis of polycyclic polyprenylated acylphloroglucinols via N-amino cyclic carbamate hydrazones: application to the total synthesis of (+)-clusianone. Organic Letters. 12: 5234-7. PMID 20977254 DOI: 10.1021/Ol1022728 |
0.813 |
|
| 2010 |
Sauer SJ, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of α-halo thioesters and enolizable aldehydes. Journal of the American Chemical Society. 132: 13997-9. PMID 20849119 DOI: 10.1021/Ja1057407 |
0.832 |
|
| 2010 |
Kohler MC, Yost JM, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a biomimetic asymmetric Mannich reaction of phenylacetate thioesters. Organic Letters. 12: 3376-9. PMID 20608684 DOI: 10.1021/Ol101152B |
0.796 |
|
| 2010 |
Hatcher JM, Coltart DM. Copper(I)-catalyzed addition of Grignard reagents to in situ-derived N-sulfonyl azoalkenes: an umpolung alkylation procedure applicable to the formation of up to three contiguous quaternary centers. Journal of the American Chemical Society. 132: 4546-7. PMID 20232808 DOI: 10.1021/Ja100932Q |
0.747 |
|
| 2010 |
Coltart D, Sauer S, Garnsey M. Reductive Enolization in Aldol Addition to Enolizable Aldehydes Synfacts. 2010: 1388-1388. DOI: 10.1055/s-0030-1258895 |
0.817 |
|
| 2009 |
Zhou G, Lim D, Fang F, Coltart DM. A practical synthesis of b-keto thioesters by direct crossed-claisen coupling of thioesters and N-acylbenzotriazoles Synthesis. 3350-3352. DOI: 10.1055/S-0029-1216971 |
0.67 |
|
| 2009 |
Yost JM, Garnsey MR, Kohler MC, Coltart DM. Direct carbon-carbon bond formation via soft enolization of thioesters: An operationally simple mannich addition reaction Synthesis. 56-58. DOI: 10.1055/S-0028-1083278 |
0.796 |
|
| 2009 |
Tarsis E, Gromova A, Lim D, Zhou G, Coltart DM. ChemInform Abstract: Overcoming the Limitations of the Morita-Baylis-Hillman Reaction: A Rapid and General Synthesis of α-Alkenyl-β′-hydroxy Thioesters. Cheminform. 40. DOI: 10.1002/chin.200912091 |
0.82 |
|
| 2008 |
Tarsis E, Gromova A, Lim D, Zhou G, Coltart DM. Overcoming the limitations of the Morita-Baylis-Hillman reaction: a rapid and general synthesis of alpha-alkenyl-beta'-hydroxy thioesters. Organic Letters. 10: 4819-22. PMID 18844367 DOI: 10.1021/Ol801896Q |
0.784 |
|
| 2008 |
Zhou G, Lim D, Coltart DM. Direct carbon-carbon bond formation via chemoselective soft enolization of thioesters: a remarkably simple and versatile crossed-Claisen reaction applied to the synthesis of LY294002. Organic Letters. 10: 3809-12. PMID 18681454 DOI: 10.1021/Ol801498U |
0.652 |
|
| 2008 |
Lim D, Coltart DM. Simple and efficient asymmetric alpha-alkylation and alpha,alpha-bisalkylation of acyclic ketones by using chiral N-amino cyclic carbamate hydrazones. Angewandte Chemie (International Ed. in English). 47: 5207-10. PMID 18528835 DOI: 10.1002/Anie.200800848 |
0.502 |
|
| 2008 |
Lim D, Zhou G, Livanos AE, Fang F, Coltart DM. MgBr2·OEt2-promoted coupling of ketones and activated acyl donors via soft enolization: A practical synthesis of 1,3-diketones Synthesis. 2148-2152. DOI: 10.1055/S-2008-1042947 |
0.662 |
|
| 2008 |
Lim D, Coltart DM. ChemInform Abstract: Simple and Efficient Asymmetric α-Alkylation and α,α-Bisalkylation of Acyclic Ketones by Using Chiral N-Amino Cyclic Carbamate Hydrazones. Cheminform. 39. DOI: 10.1002/chin.200841058 |
0.361 |
|
| 2007 |
Zhou G, Yost JM, Sauer SJ, Coltart DM. A facile and efficient anti-selective four-component direct aldol addition via chemoselective thioester enolate formation. Organic Letters. 9: 4663-5. PMID 17902688 DOI: 10.1021/Ol702240P |
0.805 |
|
| 2007 |
Lim D, Fang F, Zhou G, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a facile and efficient synthesis of 1,3-diketones. Organic Letters. 9: 4139-42. PMID 17877360 DOI: 10.1021/Ol701599V |
0.68 |
|
| 2007 |
Zhou G, Yost JM, Coltart DM. A direct aldol addition of simple thioesters employing soft enolization Synthesis. 0478-0482. DOI: 10.1055/S-2006-958959 |
0.815 |
|
| 2006 |
Yost JM, Zhou G, Coltart DM. A facile and efficient direct aldol addition of simple thioesters. Organic Letters. 8: 1503-6. PMID 16562927 DOI: 10.1021/Ol060413Q |
0.797 |
|
| 2006 |
Coltart D, Yost J, Zhou G. Efficient Aldol Addition of Simple Thioesters Synfacts. 2006: 0591-0591. DOI: 10.1055/s-2006-934524 |
0.75 |
|
| 2003 |
Clive DL, Hisaindee S, Coltart DM. Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer. The Journal of Organic Chemistry. 68: 9247-54. PMID 14629143 DOI: 10.1021/Jo030192R |
0.657 |
|
| 2003 |
Coltart DM, Danishefsky SJ. Novel synthetic approach to the 8,10-dimethyl anti-syn-anti-perhydrophenanthrene skeleton. Organic Letters. 5: 1289-92. PMID 12688741 DOI: 10.1021/Ol034213F |
0.544 |
|
| 2003 |
Keding SJ, Atsushi E, Biswas K, Zatorski A, Coltart DM, Danishefsky SJ. Hydroxynorleucine as a glycosyl acceptor is an efficient means for introducing amino acid functionality into complex carbohydrates Tetrahedron Letters. 44: 3413-3416. DOI: 10.1016/S0040-4039(03)00517-3 |
0.443 |
|
| 2002 |
Ragupathi G, Coltart DM, Williams LJ, Koide F, Kagan E, Allen J, Harris C, Glunz PW, Livingston PO, Danishefsky SJ. On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines. Proceedings of the National Academy of Sciences of the United States of America. 99: 13699-704. PMID 12359877 DOI: 10.1073/Pnas.202427599 |
0.42 |
|
| 2002 |
Coltart DM, Royyuru AK, Williams LJ, Glunz PW, Sames D, Kuduk SD, Schwarz JB, Chen XT, Danishefsky SJ, Live DH. Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains. Journal of the American Chemical Society. 124: 9833-44. PMID 12175243 DOI: 10.1021/Ja020208F |
0.639 |
|
| 2002 |
Ragupathi G, Deshpande PP, Coltart DM, Kim HM, Williams LJ, Danishefsky SJ, Livingston PO. Constructing an adenocarcinoma vaccine: immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Le(y) antibodies. International Journal of Cancer. Journal International Du Cancer. 99: 207-12. PMID 11979435 DOI: 10.1002/Ijc.10305 |
0.431 |
|
| 2002 |
Biswas K, Coltart DM, Danishefsky SJ. Construction of carbohydrate-based antitumor vaccines: Synthesis of glycosyl amino acids by olefin cross-metathesis Tetrahedron Letters. 43: 6107-6110. DOI: 10.1016/S0040-4039(02)01336-9 |
0.377 |
|
| 1999 |
Clive DL, Coltart DM, Zhou Y. Synthesis of the Angiotensin-Converting Enzyme Inhibitors (-)-A58365A and (-)-A58365B from a Common Intermediate. The Journal of Organic Chemistry. 64: 1447-1454. PMID 11674202 DOI: 10.1021/Jo9822941 |
0.617 |
|
| 1996 |
Coltart DM, Charlton JL. The asymmetric synthesis of aryltetralin lignans: (-)-isolariciresinol dimethyl ether and (-)-deoxysikkimotoxin Canadian Journal of Chemistry. 74: 88-94. DOI: 10.1139/V96-011 |
0.44 |
|
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