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Pravir Kumar, Ph.D. - Publications

Affiliations: 
1999-2004 Centre for Cardiovascular Physiology and Centre for Molecular and Cell Biology Johann Wolfgang Goethe University, Frankfurt, Germany 
 2004-2016 Neurology Tufts University School of Medicine, Boston USA 
 2008-2012 School of Biosciences and Technology Vellore institute of Technology, TamilNadu, India 
 2012- Biotechnology Delhi Technological University, Delhi, India 
Area:
Ubiquitin E3 ligase, chaperones, Neurodegenerative disorders
Website:
http://www.dtu.ac.in/Web/Departments/BioTech/faculty/
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Year Citation  Score
2021 Oli V, Gupta R, Kumar P.. FOXO and related transcription factors binding elements in the regulation of neurodegenerative disorders. J Chem Neuroanat.. 16: 102012.. PMID 34400291 DOI: doi: 10.1016/j.jchemneu.2021.102012.  0.302
2020 Advani D, Gupta R, Tripathi R, Sharma S, Ambasta RK, Kumar P. Protective role of anticancer drugs in neurodegenerative disorders: A drug repurposing approach. Neurochemistry International. 104841. PMID 32853752 DOI: 10.1016/J.Neuint.2020.104841  0.3
2020 Ambasta RK, Adeshara K, Yadav S, Kumar P. VEGF/CDK2 are involved in diabetic organ regeneration. Biochemical and Biophysical Research Communications. 529: 1094-1100. PMID 32819570 DOI: 10.1016/J.Bbrc.2020.07.014  0.315
2020 Bisht I, Ambasta RK, Kumar P. An integrated approach to unravel a putative crosstalk network in Alzheimer's disease and Parkinson's disease. Neuropeptides. 102078. PMID 32807513 DOI: 10.1016/J.Npep.2020.102078  0.322
2020 Gupta R, Ambasta RK, Kumar P. Identification of novel class I and class IIb histone deacetylase inhibitor for Alzheimer's disease therapeutics. Life Sciences. 256: 117912. PMID 32504755 DOI: 10.1016/J.Lfs.2020.117912  0.329
2020 Kumar D, Ambasta RK, Kumar P. Ubiquitin biology in neurodegenerative disorders: From impairment to therapeutic strategies. Ageing Research Reviews. 101078. PMID 32407951 DOI: 10.1016/J.Arr.2020.101078  0.397
2020 Sharan S, Kumar P, Ambasta RK. Discovery of Novel Compounds Targeting DJ-1 as Neuroprotectants for Parkinson's Disease by Virtual Screening and in Silico Method. Current Computer - Aided Drug Design. 16: 1-9. PMID 32303174 DOI: 10.2174/1573409916666200417110645  0.327
2020 Gupta R, Ambasta RK, Kumar P. Pharmacological intervention of histone deacetylase enzymes in the neurodegenerative disorders. Life Sciences. 117278. PMID 31926248 DOI: 10.1016/J.Lfs.2020.117278  0.33
2019 Kumar D, Kumar P. Aβ, Tau, and α-Synuclein aggregation and integrated role of PARK2 in the regulation and clearance of toxic peptides. Neuropeptides. 101971. PMID 31540705 DOI: 10.1016/J.Npep.2019.101971  0.39
2019 Kumar D, Kumar P. Integrated Mechanism of Lysine 351, PARK2, and STUB1 in AβPP Ubiquitination. Journal of Alzheimer's Disease : Jad. PMID 30958363 DOI: 10.3233/Jad-181219  0.365
2018 Kumar D, Kumar P. An In-Silico Investigation of Key Lysine Residues and Their Selection for Clearing off Aβ and Holo-AβPP Through Ubiquitination. Interdisciplinary Sciences, Computational Life Sciences. PMID 30194628 DOI: 10.1007/S12539-018-0307-2  0.329
2018 Jha NK, Jha SK, Sharma R, Kumar D, Ambasta RK, Kumar P. Hypoxia-Induced Signaling Activation in Neurodegenerative Diseases: Targets for New Therapeutic Strategies. Journal of Alzheimer's Disease : Jad. 62: 15-38. PMID 29439330 DOI: 10.3233/Jad-170589  0.331
2017 Jha SK, Kumar P. Molecular Docking Study Of Neuroprotective Plant-Derived Biomolecules In Parkinson’S Disease International Journal of Pharmacy and Pharmaceutical Sciences. 9: 149-155. DOI: 10.22159/Ijpps.2017V9I9.20445  0.347
2017 Jha NK, Kumar P. MOLECULAR DOCKING STUDIES FOR THE COMPARATIVE ANALYSIS OF DIFFERENT BIOMOLECULES TO TARGET HYPOXIA INDUCIBLE FACTOR-1α International Journal of Applied Pharmaceutics. 9: 83-89. DOI: 10.22159/Ijap.2017V9I4.19505  0.336
2017 Jha NK, Kumar P. Biomolecules Mediated Targeting Of Vascular Endothelial Growth Factor In Neuronal Dysfunction: An In Silico Approach Asian Journal of Pharmaceutical and Clinical Research. 10: 96-99. DOI: 10.22159/Ajpcr.2017.V10I9.19466  0.33
2017 Jha SK, Kumar P. An In Silico Study Of Naringenin-Mediated Neuroprotection In Parkinson’S Disease Asian Journal of Pharmaceutical and Clinical Research. 10: 171-176. DOI: 10.22159/Ajpcr.2017.V10I8.18709  0.369
2017 Sharma R, Kumar P. Neuroprotective Role Of Bimoclomol In Ectopic Cell Cycle In Parkinson’S Disease: New Insights Asian Journal of Pharmaceutical and Clinical Research. 10: 180-183. DOI: 10.22159/Ajpcr.2017.V10I6.17971  0.363
2016 Jha SK, Jha NK, Kumar D, Sharma R, Shrivastava A, Ambasta RK, Kumar P. Stress-Induced Synaptic Dysfunction and Neurotransmitter Release in Alzheimer's Disease: Can Neurotransmitters and Neuromodulators be Potential Therapeutic Targets? Journal of Alzheimer's Disease : Jad. PMID 27662312 DOI: 10.3233/Jad-160623  0.315
2016 Sharma R, Kumar D, Jha NK, Jha SK, Ambasta RK, Kumar P. Re-expression of cell cycle markers in aged neurons and muscles: Whether cells should divide or die? Biochimica Et Biophysica Acta. PMID 27639832 DOI: 10.1016/J.Bbadis.2016.09.010  0.34
2016 Jha SK, Jha NK, Kumar D, Ambasta RK, Kumar P. Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration. Biochimica Et Biophysica Acta. PMID 27345267 DOI: 10.1016/J.Bbadis.2016.06.015  0.363
2015 Jha NK, Jha SK, Kumar D, Kejriwal N, Sharma R, Ambasta RK, Kumar P. Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications. Journal of Alzheimer's Disease : Jad. PMID 26444774 DOI: 10.3233/Jad-150379  0.353
2015 Ambasta RK, Jha SK, Kumar D, Sharma R, Jha NK, Kumar P. Comparative study of anti-angiogenic activities of luteolin, lectin and lupeol biomolecules. Journal of Translational Medicine. 13: 307. PMID 26385094 DOI: 10.1186/S12967-015-0665-Z  0.302
2015 Kumar P, Jha NK, Jha SK, Ramani K, Ambasta RK. Tau phosphorylation, molecular chaperones, and ubiquitin E3 ligase: clinical relevance in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 43: 341-61. PMID 25096626 DOI: 10.3233/Jad-140933  0.338
2014 Kwon B, Kumar P, Lee HK, Zeng L, Walsh K, Fu Q, Barakat A, Querfurth HW. Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis. Human Molecular Genetics. 23: 3681-94. PMID 24556217 DOI: 10.1093/Hmg/Ddu077  0.349
2013 Sonia Angeline M, Sarkar A, Anand K, Ambasta RK, Kumar P. Sesamol and naringenin reverse the effect of rotenone-induced PD rat model. Neuroscience. 254: 379-94. PMID 24070629 DOI: 10.1016/J.Neuroscience.2013.09.029  0.326
2012 Sarkar A, Angeline MS, Anand K, Ambasta RK, Kumar P. Naringenin and quercetin reverse the effect of hypobaric hypoxia and elicit neuroprotective response in the murine model. Brain Research. 1481: 59-70. PMID 22981402 DOI: 10.1016/J.Brainres.2012.08.036  0.325
2012 Angeline MS, Chaterjee P, Anand K, Ambasta RK, Kumar P. Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat. Neuroscience. 220: 291-301. PMID 22710069 DOI: 10.1016/J.Neuroscience.2012.06.021  0.347
2012 Kumar P, Pradhan K, Karunya R, Ambasta RK, Querfurth HW. Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders. Journal of Neurochemistry. 120: 350-70. PMID 22098618 DOI: 10.1111/J.1471-4159.2011.07588.X  0.435
2009 Lee HK, Kumar P, Fu Q, Rosen KM, Querfurth HW. The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid. Molecular Biology of the Cell. 20: 1533-44. PMID 19144826 DOI: 10.1091/Mbc.E08-07-0777  0.335
2007 Kumar P, Ambasta RK, Veereshwarayya V, Rosen KM, Kosik KS, Band H, Mestril R, Patterson C, Querfurth HW. CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism. Human Molecular Genetics. 16: 848-64. PMID 17317785 DOI: 10.1093/Hmg/Ddm030  0.362
2006 Veereshwarayya V, Kumar P, Rosen KM, Mestril R, Querfurth HW. Differential effects of mitochondrial heat shock protein 60 and related molecular chaperones to prevent intracellular beta-amyloid-induced inhibition of complex IV and limit apoptosis. The Journal of Biological Chemistry. 281: 29468-78. PMID 16887805 DOI: 10.1074/Jbc.M602533200  0.347
2004 Ambasta RK, Kumar P, Griendling KK, Schmidt HH, Busse R, Brandes RP. Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase. The Journal of Biological Chemistry. 279: 45935-41. PMID 15322091 DOI: 10.1074/Jbc.M406486200  0.311
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