| Year |
Citation |
Score |
| 2023 |
Nikhil K, Shah K. CDK5: an oncogene or an anti-oncogene: location location location. Molecular Cancer. 22: 186. PMID 37993880 DOI: 10.1186/s12943-023-01895-8 |
0.333 |
|
| 2023 |
Shah K, Cook M. LIMK2: A Multifaceted kinase with pleiotropic roles in human physiology and pathologies. Cancer Letters. 216207. PMID 37141984 DOI: 10.1016/j.canlet.2023.216207 |
0.311 |
|
| 2022 |
Yan Y, Zhou B, Qian C, Vasquez A, Kamra M, Chatterjee A, Lee YJ, Yuan X, Ellis L, Di Vizio D, Posadas EM, Kyprianou N, Knudsen BS, Shah K, Murali R, et al. Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis. Nature Communications. 13: 669. PMID 35115556 DOI: 10.1038/s41467-022-28340-6 |
0.365 |
|
| 2020 |
Nikhil K, Haymour HS, Kamra M, Shah K. Phosphorylation-dependent regulation of SPOP by LIMK2 promotes castration-resistant prostate cancer. British Journal of Cancer. PMID 33311589 DOI: 10.1038/s41416-020-01197-6 |
0.782 |
|
| 2020 |
Nikhil K, Kamra M, Raza A, Haymour HS, Shah K. Molecular Interplay between AURKA and SPOP Dictates CRPC Pathogenesis via Androgen Receptor. Cancers. 12. PMID 33158056 DOI: 10.3390/cancers12113247 |
0.8 |
|
| 2020 |
Nikhil K, Kamra M, Raza A, Shah K. Negative cross talk between LIMK2 and PTEN promotes castration resistant prostate cancer pathogenesis in cells and in vivo. Cancer Letters. PMID 32931887 DOI: 10.1016/J.Canlet.2020.09.010 |
0.415 |
|
| 2020 |
Nikhil K, Raza A, Haymour HS, Flueckiger BV, Chu J, Shah K. Aurora Kinase A-YBX1 Synergy Fuels Aggressive Oncogenic Phenotypes and Chemoresistance in Castration-Resistant Prostate Cancer. Cancers. 12. PMID 32178290 DOI: 10.3390/Cancers12030660 |
0.809 |
|
| 2019 |
Zheng XF, Acharya SS, Choe KN, Nikhil K, Adelmant G, Satapathy SR, Sharma S, Viccaro K, Rana S, Natarajan A, Sicinski P, Marto JA, Shah K, Chowdhury D. A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1. Nature Communications. 10: 4252. PMID 31534152 DOI: 10.1038/S41467-019-12084-X |
0.794 |
|
| 2019 |
Shah K, Kim H. The significant others: Global search for direct kinase substrates using chemical approaches. Iubmb Life. PMID 30801966 DOI: 10.1002/Iub.2023 |
0.446 |
|
| 2019 |
Nikhil K, Chang L, Viccaro K, Jacobsen M, McGuire C, Satapathy SR, Tandiary M, Broman MM, Cresswell G, He YJ, Sandusky GE, Ratliff TL, Chowdhury D, Shah K. Identification of LIMK2 as a Therapeutic Target in Castration Resistant Prostate Cancer. Cancer Letters. PMID 30716360 DOI: 10.1016/J.Canlet.2019.01.035 |
0.756 |
|
| 2019 |
Zwart W, Shah K. Decision letter: AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival Elife. DOI: 10.7554/Elife.51378.Sa1 |
0.421 |
|
| 2018 |
Yan Y, Chang L, Tian H, Wang L, Zhang Y, Yang T, Li G, Hu W, Shah K, Chen G, Guo Y. 1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis. Journal For Immunotherapy of Cancer. 6: 148. PMID 30545412 DOI: 10.1186/S40425-018-0466-Z |
0.32 |
|
| 2018 |
Chaitanya MVSK, Reddy POV, Nikhil K, Kumar A, Shah K, Kumar D. Synthesis and anticancer activity studies of indolylisoxazoline analogues. Bioorganic & Medicinal Chemistry Letters. PMID 30072225 DOI: 10.1016/J.Bmcl.2018.07.035 |
0.318 |
|
| 2018 |
Nikhil K, Viccaro K, Shah K. Multifaceted Regulation of ALDH1A1 by Cdk5 in Alzheimer's Disease Pathogenesis. Molecular Neurobiology. PMID 29948941 DOI: 10.1007/S12035-018-1114-9 |
0.794 |
|
| 2018 |
Pollan SG, Huang F, Sperger JM, Lang JM, Morrissey C, Cress AE, Chu CY, Bhowmick NA, You S, Freeman MR, Spassov DS, Moasser MM, Carter WG, Satapathy SR, Shah K, et al. Regulation of inside-out β1-integrin activation by CDCP1. Oncogene. PMID 29511352 DOI: 10.1038/S41388-018-0142-2 |
0.426 |
|
| 2017 |
Nikhil K, Shah K. Cdk5-Mcl-1 axis promotes mitochondrial dysfunction and neurodegeneration in Alzheimer's disease model. Journal of Cell Science. PMID 28751497 DOI: 10.1242/Jcs.205666 |
0.416 |
|
| 2017 |
Rajasekhar K, Narayanaswamy N, Murugan NA, Viccaro K, Lee HG, Shah K, Govindaraju T. Aβ plaque-selective NIR fluorescence probe to differentiate Alzheimer's disease from tauopathies. Biosensors & Bioelectronics. 98: 54-61. PMID 28649025 DOI: 10.1016/J.Bios.2017.06.030 |
0.762 |
|
| 2017 |
Shah K, Rossie S. Tale of the Good and the Bad Cdk5: Remodeling of the Actin Cytoskeleton in the Brain. Molecular Neurobiology. PMID 28502042 DOI: 10.1007/S12035-017-0525-3 |
0.366 |
|
| 2017 |
Venkataramana Reddy PO, Mishra S, Tantak MP, Nikhil K, Sadana R, Shah K, Kumar D. Design, synthesis and in vitro cytotoxicity studies of novel β-carbolinium bromides. Bioorganic & Medicinal Chemistry Letters. PMID 28254167 DOI: 10.1016/J.Bmcl.2017.02.010 |
0.317 |
|
| 2017 |
Wang J, Nikhil K, Viccaro K, Chang L, White J, Shah K. Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer. Bmc Biology. 15: 10. PMID 28193222 DOI: 10.1186/S12915-016-0335-5 |
0.791 |
|
| 2017 |
Wang J, Nikhil K, Viccaro K, Chang L, Jacobsen M, Sandusky G, Shah K. Aurora A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma. Journal of Cell Science. PMID 28167680 DOI: 10.1242/Jcs.196790 |
0.82 |
|
| 2017 |
Pollan SG, Huang F, Lang JM, Sperger JM, Shah K, Knudsen BS. Abstract 5795: Loss of CDCP1 in patient prostate cancer metastasis leads to uncoupling of beta-1 integrin from its cytoplasmic signaling through FAK Cancer Research. 77: 5795-5795. DOI: 10.1158/1538-7445.Am2017-5795 |
0.435 |
|
| 2016 |
Shi C, Viccaro K, Lee HG, Shah K. Cdk5-Foxo3 axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models. Journal of Cell Science. 129: 1815-1830. PMID 28157684 DOI: 10.1242/Jcs.185009 |
0.8 |
|
| 2016 |
Tantak MP, Gupta V, Nikhil K, Arun V, Singh RP, Jha PN, Shah K, Kumar D. Sequential one-pot synthesis of bis(indolyl)glyoxylamides: Evaluation of antibacterial and anticancer activities. Bioorganic & Medicinal Chemistry Letters. 26: 3167-71. PMID 27173802 DOI: 10.1016/J.Bmcl.2016.04.080 |
0.31 |
|
| 2016 |
Shi C, Viccaro K, Lee HG, Shah K. Cdk5-FOXO3a axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models. Journal of Cell Science. PMID 26962010 DOI: 10.1242/jcs.185009 |
0.802 |
|
| 2016 |
Shah K, Lahiri DK. A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5. Molecular Neurobiology. PMID 26944284 DOI: 10.1007/S12035-016-9792-7 |
0.332 |
|
| 2016 |
Sundaree S, Vaddula BR, Tantak MP, Khandagale SB, Shi C, Shah K, Kumar D. Synthesis and anticancer activity study of indolyl hydrazide–hydrazones Medicinal Chemistry Research. 1-10. DOI: 10.1007/S00044-016-1522-1 |
0.34 |
|
| 2014 |
Shah K, Lahiri DK. Cdk5 activity in the brain - multiple paths of regulation. Journal of Cell Science. 127: 2391-400. PMID 24879856 DOI: 10.1242/Jcs.147553 |
0.405 |
|
| 2012 |
Kumar D, Arun V, Maruthi Kumar N, Acosta G, Noel B, Shah K. A facile synthesis of novel bis-(indolyl)-1,3,4-oxadiazoles as potent cytotoxic agents. Chemmedchem. 7: 1915-20. PMID 22997171 DOI: 10.1002/Cmdc.201200363 |
0.319 |
|
| 2012 |
Chang KH, Vincent F, Shah K. Deregulated Cdk5 triggers aberrant activation of cell cycle kinases and phosphatases inducing neuronal death. Journal of Cell Science. 125: 5124-37. PMID 22899714 DOI: 10.1242/Jcs.108183 |
0.805 |
|
| 2012 |
Johnson EO, Chang KH, Ghosh S, Venkatesh C, Giger K, Low PS, Shah K. LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy. Journal of Cell Science. 125: 1204-16. PMID 22492986 DOI: 10.1242/Jcs.092304 |
0.82 |
|
| 2012 |
Kumar D, Maruthi Kumar N, Ghosh S, Shah K. Novel bis(indolyl)hydrazide-hydrazones as potent cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 22: 212-5. PMID 22123320 DOI: 10.1016/J.Bmcl.2011.11.031 |
0.304 |
|
| 2011 |
Chi X, Amet T, Byrd D, Chang KH, Shah K, Hu N, Grantham A, Hu S, Duan J, Tao F, Nicol G, Yu Q. Direct effects of HIV-1 Tat on excitability and survival of primary dorsal root ganglion neurons: possible contribution to HIV-1-associated pain. Plos One. 6: e24412. PMID 21912693 DOI: 10.1371/Journal.Pone.0024412 |
0.749 |
|
| 2011 |
Kumar D, Kumar NM, Chang KH, Gupta R, Shah K. Synthesis and in-vitro anticancer activity of 3,5-bis(indolyl)-1,2,4-thiadiazoles. Bioorganic & Medicinal Chemistry Letters. 21: 5897-900. PMID 21873049 DOI: 10.1016/J.Bmcl.2011.07.089 |
0.756 |
|
| 2011 |
Johnson EO, Chang KH, de Pablo Y, Ghosh S, Mehta R, Badve S, Shah K. PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer. Journal of Cell Science. 124: 2711-22. PMID 21807936 DOI: 10.1242/Jcs.084970 |
0.796 |
|
| 2011 |
Sun KH, Chang KH, Clawson S, Ghosh S, Mirzaei H, Regnier F, Shah K. Glutathione-S-transferase P1 is a critical regulator of Cdk5 kinase activity. Journal of Neurochemistry. 118: 902-14. PMID 21668448 DOI: 10.1111/J.1471-4159.2011.07343.X |
0.807 |
|
| 2011 |
Kumar D, Patel G, Chavers AK, Chang KH, Shah K. Synthesis of novel 1,2,4-oxadiazoles and analogues as potential anticancer agents. European Journal of Medicinal Chemistry. 46: 3085-92. PMID 21481985 DOI: 10.1016/J.Ejmech.2011.03.031 |
0.76 |
|
| 2011 |
Kumar D, Vaddula BR, Chang KH, Shah K. One-pot synthesis and anticancer studies of 2-arylamino-5-aryl-1,3,4-thiadiazoles. Bioorganic & Medicinal Chemistry Letters. 21: 2320-3. PMID 21429743 DOI: 10.1016/J.Bmcl.2011.02.083 |
0.764 |
|
| 2011 |
Chang KH, Multani PS, Sun KH, Vincent F, de Pablo Y, Ghosh S, Gupta R, Lee HP, Lee HG, Smith MA, Shah K. Nuclear envelope dispersion triggered by deregulated Cdk5 precedes neuronal death. Molecular Biology of the Cell. 22: 1452-62. PMID 21389115 DOI: 10.1091/Mbc.E10-07-0654 |
0.792 |
|
| 2011 |
Kumar D, Narayanam MK, Chang KH, Shah K. Synthesis of novel indolyl-1,2,4-triazoles as potent and selective anticancer agents. Chemical Biology & Drug Design. 77: 182-8. PMID 21251232 DOI: 10.1111/J.1747-0285.2010.01051.X |
0.753 |
|
| 2011 |
Kumar D, Vaddula BR, Chang K, Shah K. ChemInform Abstract: One-Pot Synthesis and Anticancer Studies of 2-Arylamino-5-aryl-1,3,4-thiadiazoles. Cheminform. 42: no-no. DOI: 10.1002/chin.201134131 |
0.719 |
|
| 2010 |
Kumar D, Maruthi Kumar N, Chang KH, Shah K. Synthesis and anticancer activity of 5-(3-indolyl)-1,3,4-thiadiazoles. European Journal of Medicinal Chemistry. 45: 4664-8. PMID 20692741 DOI: 10.1016/J.Ejmech.2010.07.023 |
0.759 |
|
| 2010 |
Chang KH, de Pablo Y, Lee HP, Lee HG, Smith MA, Shah K. Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease. Journal of Neurochemistry. 113: 1221-9. PMID 20345761 DOI: 10.1111/J.1471-4159.2010.06687.X |
0.777 |
|
| 2010 |
Kumar D, Kumar NM, Sundaree S, Johnson EO, Shah K. An expeditious synthesis and anticancer activity of novel 4-(3'-indolyl)oxazoles. European Journal of Medicinal Chemistry. 45: 1244-9. PMID 20047778 DOI: 10.1016/J.Ejmech.2009.12.024 |
0.615 |
|
| 2010 |
Shah K. Chemical Genetic Approaches for Dissecting Signaling Cascades Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2214 |
0.353 |
|
| 2009 |
Sun KH, Lee HG, Smith MA, Shah K. Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease. Molecular Biology of the Cell. 20: 4611-9. PMID 19776350 DOI: 10.1091/Mbc.E09-05-0433 |
0.602 |
|
| 2009 |
Das M, Wiley DJ, Chen X, Shah K, Verde F. The conserved NDR kinase Orb6 controls polarized cell growth by spatial regulation of the small GTPase Cdc42. Current Biology : Cb. 19: 1314-9. PMID 19646873 DOI: 10.1016/J.Cub.2009.06.057 |
0.44 |
|
| 2009 |
Kumar D, Sundaree S, Johnson EO, Shah K. An efficient synthesis and biological study of novel indolyl-1,3,4-oxadiazoles as potent anticancer agents. Bioorganic & Medicinal Chemistry Letters. 19: 4492-4. PMID 19559607 DOI: 10.1016/J.Bmcl.2009.03.172 |
0.622 |
|
| 2009 |
Kumar D, Patel G, Johnson EO, Shah K. Synthesis and anticancer activities of novel 3,5-disubstituted-1,2,4-oxadiazoles. Bioorganic & Medicinal Chemistry Letters. 19: 2739-41. PMID 19376704 DOI: 10.1016/J.Bmcl.2009.03.158 |
0.632 |
|
| 2008 |
Sun KH, de Pablo Y, Vincent F, Shah K. Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction. Journal of Neurochemistry. 107: 265-78. PMID 18691386 DOI: 10.1111/J.1471-4159.2008.05616.X |
0.54 |
|
| 2008 |
Sun KH, de Pablo Y, Vincent F, Johnson EO, Chavers AK, Shah K. Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease. Molecular Biology of the Cell. 19: 3052-69. PMID 18480410 DOI: 10.1091/Mbc.E07-11-1106 |
0.749 |
|
| 2008 |
Juris SJ, Shah K, Shokat K, Dixon JE, Vacratsis PO. Corrigendum to "Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry" [FEBS Lett. 580 (2006) 179-183] (DOI:10.1016/j.febslet.2005.11.071) Febs Letters. 582: 3159. DOI: 10.1016/J.Febslet.2008.07.053 |
0.559 |
|
| 2007 |
Oh H, Ozkirimli E, Shah K, Harrison ML, Geahlen RL. Generation of an analog-sensitive Syk tyrosine kinase for the study of signaling dynamics from the B cell antigen receptor. The Journal of Biological Chemistry. 282: 33760-8. PMID 17913708 DOI: 10.1074/Jbc.M704846200 |
0.42 |
|
| 2007 |
Vincent F, Cook SP, Johnson EO, Emmert D, Shah K. Engineering unnatural nucleotide specificity to probe G protein signaling. Chemistry & Biology. 14: 1007-18. PMID 17884633 DOI: 10.1016/J.Chembiol.2007.08.006 |
0.613 |
|
| 2007 |
Kim S, Shah K. Dissecting yeast Hog1 MAP kinase pathway using a chemical genetic approach. Febs Letters. 581: 1209-16. PMID 17346711 DOI: 10.1016/J.Febslet.2007.02.032 |
0.476 |
|
| 2007 |
Schauble S, King CC, Darshi M, Koller A, Shah K, Taylor SS. Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit. The Journal of Biological Chemistry. 282: 14952-9. PMID 17242405 DOI: 10.1074/Jbc.M609221200 |
0.453 |
|
| 2006 |
Endo S, Satoh Y, Shah K, Takishima K. A single amino-acid change in ERK1/2 makes the enzyme susceptible to PP1 derivatives. Biochemical and Biophysical Research Communications. 341: 261-5. PMID 16431218 DOI: 10.1016/J.Bbrc.2005.12.179 |
0.383 |
|
| 2006 |
Juris SJ, Shah K, Shokat K, Dixon JE, Vacratsis PO. Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. Febs Letters. 580: 179-83. PMID 16364312 DOI: 10.1016/J.Febslet.2005.11.071 |
0.574 |
|
| 2005 |
Shah K, Vincent F. Divergent roles of c-Src in controlling platelet-derived growth factor-dependent signaling in fibroblasts. Molecular Biology of the Cell. 16: 5418-32. PMID 16135530 DOI: 10.1091/Mbc.E05-03-0263 |
0.403 |
|
| 2005 |
Stauffer EA, Scarborough JD, Hirono M, Miller ED, Shah K, Mercer JA, Holt JR, Gillespie PG. Fast adaptation in vestibular hair cells requires myosin-1c activity. Neuron. 47: 541-53. PMID 16102537 DOI: 10.1016/J.Neuron.2005.07.024 |
0.301 |
|
| 2005 |
Shah K. Orthogonal chemical genetic approaches for unraveling signaling pathways. Iubmb Life. 57: 397-405. PMID 16012048 DOI: 10.1080/15216540500138238 |
0.321 |
|
| 2004 |
Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T. c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. The Journal of Cell Biology. 165: 493-503. PMID 15148308 DOI: 10.1083/Jcb.200312171 |
0.402 |
|
| 2004 |
Provance DW, Gourley CR, Silan CM, Cameron LC, Shokat KM, Goldenring JR, Shah K, Gillespie PG, Mercer JA. Chemical-genetic inhibition of a sensitized mutant myosin Vb demonstrates a role in peripheral-pericentriolar membrane traffic. Proceedings of the National Academy of Sciences of the United States of America. 101: 1868-73. PMID 14766983 DOI: 10.1073/Pnas.0305895101 |
0.512 |
|
| 2004 |
Hindley AD, Park S, Wang L, Shah K, Wang Y, Hu X, Shokat KM, Kolch W, Sedivy JM, Yeung KC. Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position. Febs Letters. 556: 26-34. PMID 14706820 DOI: 10.1016/S0014-5793(03)01352-8 |
0.624 |
|
| 2003 |
Ubersax JA, Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, Shokat KM, Morgan DO. Targets of the cyclin-dependent kinase Cdk1. Nature. 425: 859-64. PMID 14574415 DOI: 10.1038/Nature02062 |
0.807 |
|
| 2003 |
Shah K, Shokat KM. A chemical genetic approach for the identification of direct substrates of protein kinases. Methods in Molecular Biology (Clifton, N.J.). 233: 253-71. PMID 12840513 DOI: 10.1385/1-59259-397-6:253 |
0.575 |
|
| 2003 |
Eblen ST, Kumar NV, Shah K, Henderson MJ, Watts CK, Shokat KM, Weber MJ. Identification of novel ERK2 substrates through use of an engineered kinase and ATP analogs. The Journal of Biological Chemistry. 278: 14926-35. PMID 12594221 DOI: 10.1074/Jbc.M300485200 |
0.638 |
|
| 2002 |
Holt JR, Gillespie SK, Provance DW, Shah K, Shokat KM, Corey DP, Mercer JA, Gillespie PG. A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell. 108: 371-81. PMID 11853671 DOI: 10.1016/S0092-8674(02)00629-3 |
0.499 |
|
| 2002 |
Shah K, Shokat KM. A chemical genetic screen for direct v-Src substrates reveals ordered assembly of a retrograde signaling pathway. Chemistry & Biology. 9: 35-47. PMID 11841937 DOI: 10.1016/S1074-5521(02)00086-8 |
0.57 |
|
| 2002 |
Witucki LA, Huang X, Shah K, Liu Y, Kyin S, Eck MJ, Shokat KM. Mutant tyrosine kinases with unnatural nucleotide specificity retain the structure and phospho-acceptor specificity of the wild-type enzyme. Chemistry & Biology. 9: 25-33. PMID 11841936 DOI: 10.1016/S1074-5521(02)00091-1 |
0.814 |
|
| 2001 |
Ting AY, Witte K, Shah K, Kraybill B, Shokat KM, Schultz PG. Phage-display evolution of tyrosine kinases with altered nucleotide specificity. Biopolymers. 60: 220-8. PMID 11774228 DOI: 10.1002/1097-0282(2001)60:3<220::Aid-Bip10035>3.0.Co;2-C |
0.818 |
|
| 2001 |
Habelhah H, Shah K, Huang L, Burlingame AL, Shokat KM, Ronai Z. Identification of new JNK substrate using ATP pocket mutant JNK and a corresponding ATP analogue. The Journal of Biological Chemistry. 276: 18090-5. PMID 11259409 DOI: 10.1074/Jbc.M011396200 |
0.568 |
|
| 2001 |
Habelhah H, Shah K, Huang L, Ostareck-Lederer A, Burlingame AL, Shokat KM, Hentze MW, Ronai Z. ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nature Cell Biology. 3: 325-30. PMID 11231586 DOI: 10.1038/35060131 |
0.551 |
|
| 2000 |
Liu Y, Witucki LA, Shah K, Bishop AC, Shokat KM. Src-Abl tyrosine kinase chimeras: replacement of the adenine binding pocket of c-Abl with v-Src to swap nucleotide and inhibitor specificities. Biochemistry. 39: 14400-8. PMID 11087392 DOI: 10.1021/Bi000437J |
0.81 |
|
| 2000 |
Bishop A, Buzko O, Heyeck-Dumas S, Jung I, Kraybill B, Liu Y, Shah K, Ulrich S, Witucki L, Yang F, Zhang C, Shokat KM. Unnatural ligands for engineered proteins: new tools for chemical genetics. Annual Review of Biophysics and Biomolecular Structure. 29: 577-606. PMID 10940260 DOI: 10.1146/Annurev.Biophys.29.1.577 |
0.744 |
|
| 2000 |
Ulrich SM, Buzko O, Shah K, Shokat KM. Towards the Engineering of an Orthogonal Protein Kinase/Nucleotide Triphosphate Pair Tetrahedron. 56: 9495-9502. DOI: 10.1016/S0040-4020(00)00834-6 |
0.816 |
|
| 2000 |
Ulrich SM, Buzko O, Shah K, Shokat KM. Towards the engineering of an orthogonal protein kinase/nucleotide triphosphate pair Tetrahedron. 56: 9495-9502. |
0.673 |
|
| 1999 |
Gillespie PG, Gillespie SK, Mercer JA, Shah K, Shokat KM. Engineering of the myosin-ibeta nucleotide-binding pocket to create selective sensitivity to N(6)-modified ADP analogs. The Journal of Biological Chemistry. 274: 31373-81. PMID 10531338 DOI: 10.1074/Jbc.274.44.31373 |
0.447 |
|
| 1999 |
Bishop AC, Kung CY, Shah K, Witucki L, Shokat KM, Liu Y. Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach Journal of the American Chemical Society. 121: 627-631. DOI: 10.1021/Ja983267V |
0.822 |
|
| 1998 |
Liu Y, Shah K, Yang F, Witucki L, Shokat KM. A molecular gate which controls unnatural ATP analogue recognition by the tyrosine kinase v-Src. Bioorganic & Medicinal Chemistry. 6: 1219-26. PMID 9784863 DOI: 10.1016/S0968-0896(98)00099-6 |
0.794 |
|
| 1998 |
Bishop AC, Shah K, Liu Y, Witucki L, Kung C, Shokat KM. Design of allele-specific inhibitors to probe protein kinase signaling. Current Biology : Cb. 8: 257-66. PMID 9501066 DOI: 10.1016/S0960-9822(98)70198-8 |
0.806 |
|
| 1998 |
Liu Y, Shah K, Yang F, Witucki L, Shokat KM. Engineering Src family protein kinases with unnatural nucleotide specificity. Chemistry & Biology. 5: 91-101. PMID 9495830 DOI: 10.1016/S1074-5521(98)90143-0 |
0.818 |
|
| 1997 |
Shah K, Liu Y, Deirmengian C, Shokat KM. Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates. Proceedings of the National Academy of Sciences of the United States of America. 94: 3565-70. PMID 9108016 DOI: 10.1073/Pnas.94.8.3565 |
0.644 |
|
| Show low-probability matches. |
