Tim Thomas - Publications

Affiliations: 
Development and Neurobiology The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gan L, Sun J, Yang S, Zhang X, Chen W, Sun Y, Wu X, Cheng C, Yuan J, Li A, Corbett MA, Dixon MP, Thomas T, Voss AK, Gécz J, et al. Chromatin-Binding Protein PHF6 Regulates Activity-Dependent Transcriptional Networks to Promote Hunger Response. Cell Reports. 30: 3717-3728.e6. PMID 32187544 DOI: 10.1016/j.celrep.2020.02.085  0.36
2020 Priebbenow DL, Leaver D, Nguyen N, Cleary B, Lagiakos HR, Sanchez J, Xue L, Huang F, Sun Y, Mujumdar P, Mudududdla R, Varghese S, Teguh SC, Charman SA, White KL, ... ... Thomas T, et al. Discovery of Acylsulfonohydrazide-Derived Lysine Acetyltransferase (KAT6A) Inhibitors as Potent Senescence-Inducing Anti-Cancer Agents. Journal of Medicinal Chemistry. PMID 32118427 DOI: 10.1021/acs.jmedchem.9b02071  0.36
2019 MacPherson L, Anokye J, Yeung MM, Lam EYN, Chan YC, Weng CF, Yeh P, Knezevic K, Butler MS, Hoegl A, Chan KL, Burr ML, Gearing LJ, Willson T, Liu J, ... ... Thomas T, et al. HBO1 is required for the maintenance of leukaemia stem cells. Nature. PMID 31827282 DOI: 10.1038/s41586-019-1835-6  0.36
2019 Kueh AJ, Eccles S, Tang L, Garnham AL, May RE, Herold MJ, Smyth GK, Voss AK, Thomas T. HBO1(KAT7) does not have an essential role in cell proliferation, DNA replication or histone 4 acetylation in human cells. Molecular and Cellular Biology. PMID 31767635 DOI: 10.1128/MCB.00506-19  0.36
2019 Klein BJ, Jang SM, Lachance C, Mi W, Lyu J, Sakuraba S, Krajewski K, Wang WW, Sidoli S, Liu J, Zhang Y, Wang X, Warfield BM, Kueh AJ, Voss AK, ... Thomas T, et al. Histone H3K23-specific acetylation by MORF is coupled to H3K14 acylation. Nature Communications. 10: 4724. PMID 31624313 DOI: 10.1038/s41467-019-12551-5  0.36
2019 Vanyai HK, Garnham A, May RE, McRae HM, Collin C, Wilcox S, Smyth GK, Thomas T, Voss AK. MOZ directs the distal-less homeobox gene expression program during craniofacial development. Development (Cambridge, England). 146. PMID 31340933 DOI: 10.1242/dev.175042  0.36
2019 McRae HM, Voss AK, Thomas T. Are transplantable stem cells required for adult hematopoiesis? Experimental Hematology. PMID 31175894 DOI: 10.1016/j.exphem.2019.05.007  0.36
2019 Delbridge ARD, Kueh AJ, Ke F, Zamudio NM, El-Saafin F, Jansz N, Wang GY, Iminitoff M, Beck T, Haupt S, Hu Y, May RE, Whitehead L, Tai L, Chiang W, ... ... Thomas T, et al. Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects. Cell Reports. 27: 442-454.e5. PMID 30970248 DOI: 10.1016/j.celrep.2019.03.048  0.36
2019 Urdinguio RG, Lopez V, Bayón GF, Diaz de la Guardia R, Sierra MI, García-Toraño E, Perez RF, García MG, Carella A, Pruneda PC, Prieto C, Dmitrijeva M, Santamarina P, Belmonte T, Mangas C, ... ... Thomas T, et al. Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment. Nucleic Acids Research. PMID 30923829 DOI: 10.1093/nar/gkz195  0.36
2019 McRae HM, Garnham AL, Hu Y, Witkowski MT, Corbett MA, Dixon MP, May RE, Sheikh BN, Chiang W, Kueh AJ, Nguyen TA, Man K, Gloury R, Aubrey BJ, Policheni A, ... ... Thomas T, et al. PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia. Blood. PMID 30755422 DOI: 10.1182/blood-2018-07-860726  0.36
2018 Voss AK, Thomas T. Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1800078. PMID 30144132 DOI: 10.1002/bies.201800078  0.36
2018 Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, ... ... Thomas T, et al. Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature. PMID 30069049 DOI: 10.1038/s41586-018-0387-5  0.36
2018 El-Saafin F, Curry C, Ye T, Garnier JM, Kolb-Cheynel I, Stierle M, Downer NL, Dixon MP, Negroni L, Berger I, Thomas T, Voss AK, Dobyns W, Devys D, Tora L. Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA Polymerase II transcription. Human Molecular Genetics. PMID 29648665 DOI: 10.1093/hmg/ddy126  0.36
2016 Sheikh BN, Metcalf D, Voss AK, Thomas T. MOZ and BMI1 act synergistically to maintain Hematopoietic Stem Cells. Experimental Hematology. PMID 27773671 DOI: 10.1016/j.exphem.2016.10.006  0.36
2016 Newman DM, Voss AK, Thomas T, Allan RS. Essential role for the histone acetyltransferase KAT7 in T cell development, fitness, and survival. Journal of Leukocyte Biology. PMID 27733580 DOI: 10.1189/jlb.1MA0816-338R  0.36
2016 Sheikh BN, Yang Y, Schreuder J, Nilsson SK, Bilardi R, Carotta S, McRae HM, Metcalf D, Voss AK, Thomas T. MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells. Blood. PMID 27663673 DOI: 10.1182/blood-2015-10-676072  0.36
2016 Newman DM, Sakaguchi S, Lun A, Preston S, Pellegrini M, Khamina K, Bergthaler A, Nutt SL, Smyth GK, Voss AK, Thomas T, Ellmeier W, Belz GT, Allan RS. Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity. Cell Reports. 16: 3311-21. PMID 27653692 DOI: 10.1016/j.celrep.2016.08.056  0.36
2015 Lawrenson ID, Krebs DL, Linossi EM, Zhang JG, McLennan TJ, Collin C, McRae HM, Kolesnik TB, Koh K, Britto JM, Kueh AJ, Sheikh BN, El-Saafin F, Nicola NA, Tan SS, ... ... Thomas T, et al. Cortical Layer Inversion and Deregulation of Reelin Signaling in the Absence of SOCS6 and SOCS7. Cerebral Cortex (New York, N.Y. : 1991). PMID 26503265 DOI: 10.1093/cercor/bhv253  0.36
2015 Moulin M, Voss AK, Thomas T, Wong WW, Cook WD, Koentgen F, Vince J, Silke J, Vaux DL. Response to Heard et al. The Embo Journal. 34: 2396-7. PMID 26427759 DOI: 10.15252/embj.201592761  0.36
2015 Sheikh BN, Downer NL, Phipson B, Vanyai HK, Kueh AJ, McCarthy DJ, Smyth GK, Thomas T, Voss AK. MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo. Proceedings of the National Academy of Sciences of the United States of America. 112: 5437-42. PMID 25922517 DOI: 10.1073/pnas.1422872112  0.36
2015 Vanyai HK, Thomas T, Voss AK. Mesodermal expression of Moz is necessary for cardiac septum development. Developmental Biology. 403: 22-9. PMID 25912687 DOI: 10.1016/j.ydbio.2015.04.011  0.36
2015 Sheikh BN, Lee SC, El-Saafin F, Vanyai HK, Hu Y, Pang SH, Grabow S, Strasser A, Nutt SL, Alexander WS, Smyth GK, Voss AK, Thomas T. MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development. Blood. 125: 1910-21. PMID 25605372 DOI: 10.1182/blood-2014-08-594655  0.36
2014 Tan KL, Ling KH, Hewitt CA, Cheah PS, Simpson K, Gordon L, Pritchard MA, Smyth GK, Thomas T, Scott HS. Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome. Genomics Data. 2: 314-7. PMID 26484118 DOI: 10.1016/j.gdata.2014.09.009  0.36
2014 Sheikh BN, Downer NL, Kueh AJ, Thomas T, Voss AK. Excessive versus physiologically relevant levels of retinoic acid in embryonic stem cell differentiation. Stem Cells (Dayton, Ohio). 32: 1451-8. PMID 25099890 DOI: 10.1002/stem.1604  0.36
2014 Ling KH, Hewitt CA, Tan KL, Cheah PS, Vidyadaran S, Lai MI, Lee HC, Simpson K, Hyde L, Pritchard MA, Smyth GK, Thomas T, Scott HS. Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks. Bmc Genomics. 15: 624. PMID 25052193 DOI: 10.1186/1471-2164-15-624  0.36
2014 Good-Jacobson KL, Chen Y, Voss AK, Smyth GK, Thomas T, Tarlinton D. Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ. Proceedings of the National Academy of Sciences of the United States of America. 111: 9585-90. PMID 24979783 DOI: 10.1073/pnas.1402485111  0.36
2012 Voss AK, Vanyai HK, Collin C, Dixon MP, McLennan TJ, Sheikh BN, Scambler P, Thomas T. MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome. Developmental Cell. 23: 652-63. PMID 22921202 DOI: 10.1016/j.devcel.2012.07.010  0.36
2012 Yip YP, Thomas T, Voss AK, Yip JW. Migration of sympathetic preganglionic neurons in the spinal cord of a C3G-deficient mouse suggests that C3G acts in the reelin signaling pathway Journal of Comparative Neurology. 520: 3194-3202. PMID 22351125 DOI: 10.1002/cne.23086  0.36
2012 Sheikh BN, Dixon MP, Thomas T, Voss AK. Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells. Journal of Cell Science. 125: 295-309. PMID 22331353 DOI: 10.1242/jcs.077271  0.36
2012 Moulin M, Anderton H, Voss AK, Thomas T, Wong WW, Bankovacki A, Feltham R, Chau D, Cook WD, Silke J, Vaux DL. IAPs limit activation of RIP kinases by TNF receptor 1 during development. The Embo Journal. 31: 1679-91. PMID 22327219 DOI: 10.1038/emboj.2012.18  0.36
2012 Howitt J, Lackovic J, Low LH, Naguib A, Macintyre A, Goh CP, Callaway JK, Hammond V, Thomas T, Dixon M, Putz U, Silke J, Bartlett P, Yang B, Kumar S, et al. Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. The Journal of Cell Biology. 196: 29-36. PMID 22213801 DOI: 10.1083/jcb.201105009  0.36
2012 Voss AK, Dixon MP, McLennan T, Kueh AJ, Thomas T. Chromatin immunoprecipitation of mouse embryos. Methods in Molecular Biology (Clifton, N.J.). 809: 335-52. PMID 22113287 DOI: 10.1007/978-1-61779-376-9_23  0.36
2011 Falk H, Connor T, Yang H, Loft KJ, Alcindor JL, Nikolakopoulos G, Surjadi RN, Bentley JD, Hattarki MK, Dolezal O, Murphy JM, Monahan BJ, Peat TS, Thomas T, Baell JB, et al. An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets. Journal of Biomolecular Screening. 16: 1196-205. PMID 22086725 DOI: 10.1177/1087057111421631  0.36
2011 Clayton-Smith J, O'Sullivan J, Daly S, Bhaskar S, Day R, Anderson B, Voss AK, Thomas T, Biesecker LG, Smith P, Fryer A, Chandler KE, Kerr B, Tassabehji M, Lynch SA, et al. Whole-exome-sequencing identifies mutations in histone acetyltransferase gene KAT6B in individuals with the Say-Barber-Biesecker variant of Ohdo syndrome. American Journal of Human Genetics. 89: 675-81. PMID 22077973 DOI: 10.1016/j.ajhg.2011.10.008  0.36
2011 Kraft M, Cirstea IC, Voss AK, Thomas T, Goehring I, Sheikh BN, Gordon L, Scott H, Smyth GK, Ahmadian MR, Trautmann U, Zenker M, Tartaglia M, Ekici A, Reis A, et al. Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice. The Journal of Clinical Investigation. 121: 3479-91. PMID 21804188 DOI: 10.1172/JCI43428  0.36
2011 Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson TA, Collin C, Thomas T, Voss AK, Kile BT, Alexander WS, Pimanda JE, Hilton DJ. ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes & Development. 25: 251-62. PMID 21245161 DOI: 10.1101/gad.2009211  0.36
2011 Kueh AJ, Dixon MP, Voss AK, Thomas T. HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development. Molecular and Cellular Biology. 31: 845-60. PMID 21149574 DOI: 10.1128/MCB.00159-10  0.36
2011 Ling KH, Hewitt CA, Beissbarth T, Hyde L, Cheah PS, Smyth GK, Tan SS, Hahn CN, Thomas T, Thomas PQ, Scott HS. Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis. Cerebral Cortex (New York, N.Y. : 1991). 21: 683-97. PMID 20693275 DOI: 10.1093/cercor/bhq141  0.36
2010 Hewitt CA, Ling KH, Merson TD, Simpson KM, Ritchie ME, King SL, Pritchard MA, Smyth GK, Thomas T, Scott HS, Voss AK. Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome. Plos One. 5: e11561. PMID 20661276 DOI: 10.1371/journal.pone.0011561  0.36
2009 Voss AK, Collin C, Dixon MP, Thomas T. Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity. Developmental Cell. 17: 674-86. PMID 19922872 DOI: 10.1016/j.devcel.2009.10.006  0.36
2009 Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas T, Scott HS. Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling. Genome Biology. 10: R104. PMID 19799774 DOI: 10.1186/gb-2009-10-10-r104  0.36
2009 Voss AK, Thomas T. MYST family histone acetyltransferases take center stage in stem cells and development. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 31: 1050-61. PMID 19722182 DOI: 10.1002/bies.200900051  0.36
2008 Thomas T, Dixon MP, Kueh AJ, Voss AK. Mof (MYST1 or KAT8) is essential for progression of embryonic development past the blastocyst stage and required for normal chromatin architecture. Molecular and Cellular Biology. 28: 5093-105. PMID 18541669 DOI: 10.1128/MCB.02202-07  0.36
2008 Voss AK, Britto JM, Dixon MP, Sheikh BN, Collin C, Tan SS, Thomas T. C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment. Development (Cambridge, England). 135: 2139-49. PMID 18506028 DOI: 10.1242/dev.016725  0.36
2007 Voss AK, Gamble R, Collin C, Shoubridge C, Corbett M, Gécz J, Thomas T. Protein and gene expression analysis of Phf6, the gene mutated in the Börjeson-Forssman-Lehmann Syndrome of intellectual disability and obesity. Gene Expression Patterns : Gep. 7: 858-71. PMID 17698420 DOI: 10.1016/j.modgep.2007.06.007  0.36
2007 Coultas L, Terzano S, Thomas T, Voss A, Reid K, Stanley EG, Scott CL, Bouillet P, Bartlett P, Ham J, Adams JM, Strasser A. Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis. Journal of Cell Science. 120: 2044-52. PMID 17535852 DOI: 10.1242/jcs.002063  0.36
2007 Thomas T, Loveland KL, Voss AK. The genes coding for the MYST family histone acetyltransferases, Tip60 and Mof, are expressed at high levels during sperm development. Gene Expression Patterns : Gep. 7: 657-65. PMID 17517537 DOI: 10.1016/j.modgep.2007.03.005  0.36
2007 Thomas T, Voss AK. The diverse biological roles of MYST histone acetyltransferase family proteins. Cell Cycle (Georgetown, Tex.). 6: 696-704. PMID 17374998 DOI: 10.4161/cc.6.6.4013  0.36
2006 Merson TD, Dixon MP, Collin C, Rietze RL, Bartlett PF, Thomas T, Voss AK. The transcriptional coactivator Querkopf controls adult neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11359-70. PMID 17079664 DOI: 10.1523/JNEUROSCI.2247-06.2006  0.36
2006 Voss AK, Krebs DL, Thomas T. C3G regulates the size of the cerebral cortex neural precursor population. The Embo Journal. 25: 3652-63. PMID 16858399 DOI: 10.1038/sj.emboj.7601234  0.36
2006 Thomas T, Corcoran LM, Gugasyan R, Dixon MP, Brodnicki T, Nutt SL, Metcalf D, Voss AK. Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. Genes & Development. 20: 1175-86. PMID 16651658 DOI: 10.1101/gad.1382606  0.36
2006 Hirst CE, Ng ES, Azzola L, Voss AK, Thomas T, Stanley EG, Elefanty AG. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Developmental Biology. 293: 90-103. PMID 16546155 DOI: 10.1016/j.ydbio.2006.01.023  0.36
2004 Krebs DL, Metcalf D, Merson TD, Voss AK, Thomas T, Zhang JG, Rakar S, O'bryan MK, Willson TA, Viney EM, Mielke LA, Nicola NA, Hilton DJ, Alexander WS. Development of hydrocephalus in mice lacking SOCS7. Proceedings of the National Academy of Sciences of the United States of America. 101: 15446-51. PMID 15494444 DOI: 10.1073/pnas.0406870101  0.36
2004 Katschinski DM, Le L, Schindler SG, Thomas T, Voss AK, Wenger RH. Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 14: 351-60. PMID 15319539 DOI: 10.1159/000080345  0.36
2004 Thomas T, Voss AK. Querkopf, a histone acetyltransferase, is essential for embryonic neurogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 9: 24-31. PMID 14766340  0.36
2003 Ting SB, Wilanowski T, Auden A, Hall M, Voss AK, Thomas T, Parekh V, Cunningham JM, Jane SM. Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3 Nature Medicine. 9: 1513-1519. PMID 14608380 DOI: 10.1038/nm961  0.36
2003 Burdon KP, McKay JD, Sale MM, Russell-Eggitt IM, Mackey DA, Wirth MG, Elder JE, Nicoll A, Clarke MP, FitzGerald LM, Stankovich JM, Shaw MA, Sharma S, Gajovic S, Gruss P, ... ... Thomas T, et al. Mutations in a novel gene, NHS, cause the pleiotropic effects of Nance-Horan syndrome, including severe congenital cataract, dental anomalies, and mental retardation. American Journal of Human Genetics. 73: 1120-30. PMID 14564667 DOI: 10.1086/379381  0.36
2003 Voss AK, Gruss P, Thomas T. The guanine nucleotide exchange factor C3G is necessary for the formation of focal adhesions and vascular maturation. Development (Cambridge, England). 130: 355-67. PMID 12466202 DOI: 10.1242/dev.00217  0.36
2002 Stecca B, Nait-Oumesmar B, Kelley KA, Voss AK, Thomas T, Lazzarini RA. Gcm1 expression defines three stages of chorio-allantoic interaction during placental development. Mechanisms of Development. 115: 27-34. PMID 12049764 DOI: 10.1016/S0925-4773(02)00095-3  0.36
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