Year |
Citation |
Score |
2021 |
Uzor S, Porazinski SR, Li L, Clark B, Ajiro M, Iida K, Hagiwara M, Alqasem AA, Perks CM, Wilson ID, Oltean S, Ladomery MR. CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer. Scientific Reports. 11: 7963. PMID 33846420 DOI: 10.1038/s41598-021-86908-6 |
0.332 |
|
2020 |
Belali T, Wodi C, Clark B, Cheung MK, Craig TJ, Wheway G, Wagner N, Wagner KD, Roberts S, Porazinski S, Ladomery M. WT1 activates transcription of the splice factor kinase SRPK1 gene in PC3 and K562 cancer cells in the absence of corepressor BASP1. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194642. PMID 33017668 DOI: 10.1016/j.bbagrm.2020.194642 |
0.384 |
|
2020 |
Li L, Hobson L, Perry L, Clark B, Heavey S, Haider A, Sridhar A, Shaw G, Kelly J, Freeman A, Wilson I, Whitaker H, Nurmemmedov E, Oltean S, Porazinski S, ... Ladomery M, et al. Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer. British Journal of Cancer. PMID 32581342 DOI: 10.1038/S41416-020-0951-2 |
0.358 |
|
2019 |
Koschorke A, Faraci S, Giani D, Chiodoni C, Iorio E, Canese R, Colombo MP, Lamolinara A, Iezzi M, Ladomery M, Vernieri C, de Braud F, Di Nicola M, Tagliabue E, Castagnoli L, et al. Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. Cellular Oncology (Dordrecht). PMID 31376137 DOI: 10.1007/S13402-019-00464-W |
0.3 |
|
2019 |
Castagnoli L, Ladomery M, Tagliabue E, Pupa SM. The d16HER2 Splice Variant: A Friend or Foe of HER2-Positive Cancers? Cancers. 11. PMID 31261614 DOI: 10.3390/Cancers11070902 |
0.34 |
|
2019 |
Wagner KD, El Maï M, Ladomery M, Belali T, Leccia N, Michiels JF, Wagner N. Altered VEGF Splicing Isoform Balance in Tumor Endothelium Involves Activation of Splicing Factors Srpk1 and Srsf1 by the Wilms' Tumor Suppressor Wt1. Cells. 8. PMID 30641926 DOI: 10.3390/Cells8010041 |
0.471 |
|
2018 |
Uzor S, Zorzou P, Bowler E, Porazinski S, Wilson I, Ladomery M. Autoregulation of the human splice factor kinase CLK1 through exon skipping and intron retention. Gene. PMID 29802995 DOI: 10.1016/j.gene.2018.05.095 |
0.377 |
|
2018 |
Antonopoulou E, Ladomery M. Targeting Splicing in Prostate Cancer. International Journal of Molecular Sciences. 19. PMID 29693622 DOI: 10.3390/Ijms19051287 |
0.411 |
|
2018 |
Bowler E, Porazinski S, Uzor S, Thibault P, Durand M, Lapointe E, Rouschop KMA, Hancock J, Wilson I, Ladomery M. Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells. Bmc Cancer. 18: 355. PMID 29606096 DOI: 10.1186/S12885-018-4227-7 |
0.405 |
|
2018 |
Porazinski S, Ladomery M. Alternative Splicing in the Hippo Pathway-Implications for Disease and Potential Therapeutic Targets. Genes. 9. PMID 29534050 DOI: 10.3390/Genes9030161 |
0.331 |
|
2017 |
Adamo P, Porazinski S, Rajatileka S, Jumbe S, Hagen R, Cheung MK, Wilson I, Ladomery MR. The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells. Oncology Letters. 14: 5605-5610. PMID 29113189 DOI: 10.3892/ol.2017.6841 |
0.301 |
|
2015 |
Ciuzan O, Hancock J, Pamfil D, Wilson I, Ladomery M. The evolutionarily conserved multifunctional glycine-rich RNA-binding proteins play key roles in development and stress adaptation. Physiologia Plantarum. 153: 1-11. PMID 25243592 DOI: 10.1111/Ppl.12286 |
0.398 |
|
2015 |
Hamdollah Zadeh MA, Amin EM, Hoareau-Aveilla C, Domingo E, Symonds KE, Ye X, Heesom KJ, Salmon A, D'Silva O, Betteridge KB, Williams AC, Kerr DJ, Salmon AH, Oltean S, Midgley RS, ... Ladomery MR, et al. Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance. Molecular Oncology. 9: 167-78. PMID 25224594 DOI: 10.1016/J.Molonc.2014.07.017 |
0.571 |
|
2014 |
Mavrou A, Brakspear K, Hamdollah-Zadeh M, Damodaran G, Babaei-Jadidi R, Oxley J, Gillatt DA, Ladomery MR, Harper SJ, Bates DO, Oltean S. Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer. Oncogene. PMID 25381816 DOI: 10.1038/Onc.2014.360 |
0.566 |
|
2013 |
Sette C, Ladomery M, Ghigna C. Alternative splicing: role in cancer development and progression. International Journal of Cell Biology. 2013: 421606. PMID 24348561 DOI: 10.1155/2013/421606 |
0.451 |
|
2013 |
Ladomery M. Aberrant alternative splicing is another hallmark of cancer. International Journal of Cell Biology. 2013: 463786. PMID 24101931 DOI: 10.1155/2013/463786 |
0.429 |
|
2012 |
Oltean S, Gammons M, Hulse R, Hamdollah-Zadeh M, Mavrou A, Donaldson L, Salmon AH, Harper SJ, Ladomery MR, Bates DO. SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases. Biochemical Society Transactions. 40: 831-5. PMID 22817743 DOI: 10.1042/Bst20120051 |
0.589 |
|
2011 |
Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, ... ... Ladomery MR, et al. WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell. 20: 768-80. PMID 22172722 DOI: 10.1016/J.Ccr.2011.10.016 |
0.569 |
|
2010 |
Nowak DG, Amin EM, Rennel ES, Hoareau-Aveilla C, Gammons M, Damodoran G, Hagiwara M, Harper SJ, Woolard J, Ladomery MR, Bates DO. Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis. The Journal of Biological Chemistry. 285: 5532-40. PMID 19906640 DOI: 10.1074/Jbc.M109.074930 |
0.594 |
|
2010 |
Schmidt F, Marnef A, Cheung MK, Wilson I, Hancock J, Staiger D, Ladomery M. A proteomic analysis of oligo(dT)-bound mRNP containing oxidative stress-induced Arabidopsis thaliana RNA-binding proteins ATGRP7 and ATGRP8. Molecular Biology Reports. 37: 839-45. PMID 19672695 DOI: 10.1007/S11033-009-9636-X |
0.373 |
|
2009 |
Camats M, Kokolo M, Heesom KJ, Ladomery M, Bach-Elias M. P19 H-ras induces G1/S phase delay maintaining cells in a reversible quiescence state. Plos One. 4: e8513. PMID 20046837 DOI: 10.1371/Journal.Pone.0008513 |
0.3 |
|
2008 |
Nowak DG, Woolard J, Amin EM, Konopatskaya O, Saleem MA, Churchill AJ, Ladomery MR, Harper SJ, Bates DO. Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. Journal of Cell Science. 121: 3487-95. PMID 18843117 DOI: 10.1242/Jcs.016410 |
0.6 |
|
2007 |
Morrison AA, Venables JP, Dellaire G, Ladomery MR. The Wilms tumour suppressor protein WT1 (+KTS isoform) binds alpha-actinin 1 mRNA via its zinc-finger domain. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 789-98. PMID 17167543 DOI: 10.1139/O06-065 |
0.421 |
|
2007 |
Ladomery MR, Harper SJ, Bates DO. Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm. Cancer Letters. 249: 133-42. PMID 17027147 DOI: 10.1016/J.Canlet.2006.08.015 |
0.566 |
|
2007 |
Nowak DG, Amin E, Ladomery MR, Harper SJ, Bates DO. Selective upregulation of anti‐angiogenic splice variants of VEGF by TGF‐β1 is mediated by Cdc2‐like kinase family (Clk) and p38 MAPK The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A248-D |
0.478 |
|
2006 |
Markus MA, Heinrich B, Raitskin O, Adams DJ, Mangs H, Goy C, Ladomery M, Sperling R, Stamm S, Morris BJ. WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Experimental Cell Research. 312: 3379-88. PMID 16934801 DOI: 10.1016/J.Yexcr.2006.07.008 |
0.438 |
|
2006 |
Bor YC, Swartz J, Morrison A, Rekosh D, Ladomery M, Hammarskjöld ML. The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron. Genes & Development. 20: 1597-608. PMID 16738405 DOI: 10.1101/Gad.1402306 |
0.395 |
|
2003 |
Ladomery M, Sommerville J, Woolner S, Slight J, Hastie N. Expression in Xenopus oocytes shows that WT1 binds transcripts in vivo, with a central role for zinc finger one. Journal of Cell Science. 116: 1539-49. PMID 12640038 DOI: 10.1242/jcs.00324 |
0.31 |
|
2003 |
Ladomery M, Dellaire G. Multifunctional zinc finger proteins in development and disease. Annals of Human Genetics. 66: 331-42. PMID 12485467 DOI: 10.1046/J.1469-1809.2002.00121.X |
0.362 |
|
1998 |
Ladomery M. Multifunctional proteins suggest connections between transcriptional and post-transcriptional processes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 19: 903-9. PMID 9363684 DOI: 10.1002/BIES.950191010 |
0.301 |
|
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