Xiaobo Mao, Ph.D - Publications

Affiliations: 
2010- Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Area:
Neurodegeneration, alpha-synuclein, amyloid
Website:
http://www.hopkinsmedicine.org/profiles/results/directory/profile/10003736/xiaobo-mao

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Kotha S, Kuo G, Katakam S, Jeong D, Wang L, Wang A, Chen R, ... ... Mao X, et al. Lymphocyte-Activation Gene 3 Facilitates Pathological Tau Neuron-to-Neuron Transmission. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2303775. PMID 38327094 DOI: 10.1002/advs.202303775  0.642
2023 Shastry S, Hu J, Ying M, Mao X. Cell Therapy for Parkinson's Disease. Pharmaceutics. 15. PMID 38139997 DOI: 10.3390/pharmaceutics15122656  0.375
2023 Wang H, Yin X, Xu J, Chen L, Karuppagounder SS, Xu E, Mao X, Dawson VL, Dawson TM. Interspecies chimerism with human embryonic stem cells generates functional human dopamine neurons at low efficiency. Stem Cell Reports. PMID 38134925 DOI: 10.1016/j.stemcr.2023.11.009  0.675
2023 Kang H, Park S, Jo A, Mao X, Kumar M, Park CH, Ahn JY, Lee Y, Choi JY, Lee YS, Dawson VL, Dawson TM, Kam TI, Shin JH. PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification. Embo Reports. e56166. PMID 37870275 DOI: 10.15252/embr.202256166  0.61
2023 Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Katakam S, Jeong D, Wang L, Wang A, Chen R, Zhang S, Jin L, ... ... Mao X, et al. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. Biorxiv : the Preprint Server For Biology. PMID 37293032 DOI: 10.1101/2023.05.16.541015  0.635
2023 Deyell JS, Sriparna M, Ying M, Mao X. The Interplay between α-Synuclein and Microglia in α-Synucleinopathies. International Journal of Molecular Sciences. 24. PMID 36768798 DOI: 10.3390/ijms24032477  0.438
2022 Butler YR, Liu Y, Kumbhar R, Zhao P, Gadhave K, Wang N, Li Y, Mao X, Wang W. α-Synuclein fibril-specific nanobody reduces prion-like α-synuclein spreading in mice. Nature Communications. 13: 4060. PMID 35853942 DOI: 10.1038/s41467-022-31787-2  0.455
2022 Panicker N, Kam TI, Wang H, Neifert S, Chou SC, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, Mao X, Xu E, Karuppagounder SS, Hsu ET, Kang SU, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. PMID 35654037 DOI: 10.1016/j.neuron.2022.05.009  0.77
2021 Seo BA, Kim D, Hwang H, Kim MS, Ma SX, Kwon SH, Kweon SH, Wang H, Yoo JM, Choi S, Kwon SH, Kang SU, Kam TI, Kim K, Karuppagounder SS, ... ... Mao X, et al. TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron. PMID 34644545 DOI: 10.1016/j.neuron.2021.09.031  0.697
2021 Jo A, Lee Y, Kam TI, Kang SU, Neifert S, Karuppagounder SS, Khang R, Kang H, Park H, Chou SC, Oh S, Jiang H, Swing DA, Ham S, Pirooznia S, ... ... Mao X, et al. PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease. Science Translational Medicine. 13. PMID 34321320 DOI: 10.1126/scitranslmed.aax8891  0.705
2021 Zhang S, Liu YQ, Jia C, Lim YJ, Feng G, Xu E, Long H, Kimura Y, Tao Y, Zhao C, Wang C, Liu Z, Hu JJ, Ma MR, Liu Z, ... ... Mao X, et al. Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34172566 DOI: 10.1073/pnas.2011196118  0.707
2021 Li A, Tyson J, Patel S, Patel M, Katakam S, Mao X, He W. Emerging Nanotechnology for Treatment of Alzheimer's and Parkinson's Disease. Frontiers in Bioengineering and Biotechnology. 9: 672594. PMID 34113606 DOI: 10.3389/fbioe.2021.672594  0.36
2021 Gu H, Yang X, Mao X, Xu E, Qi C, Wang H, Brahmachari S, York B, Sriparna M, Li A, Chang M, Patel P, Dawson VL, Dawson TM. Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice. Frontiers in Cellular Neuroscience. 15: 656426. PMID 33776654 DOI: 10.3389/fncel.2021.656426  0.695
2020 Jia L, Liu Y, Wang W, Wang Y, Liu H, Liu F, Chen R, Dawson VL, Dawson TM, Lu F, Liu L, Wang Y, Mao X. Molecular Mediation of Prion-like α-Synuclein Fibrillation from Toxic PFFs to Nontoxic Species. Acs Applied Bio Materials. 3: 6096-6102. PMID 35021742 DOI: 10.1021/acsabm.0c00684  0.703
2020 Henrich MT, Geibl FF, Lakshminarasimhan H, Stegmann A, Giasson BI, Mao X, Dawson VL, Dawson TM, Oertel WH, Surmeier DJ. Determinants of seeding and spreading of α-synuclein pathology in the brain. Science Advances. 6. PMID 33177086 DOI: 10.1126/sciadv.abc2487  0.721
2020 Gao R, Chen C, Zhao Q, Li M, Wang Q, Zhou L, Chen E, Chen H, Zhang Y, Cai X, Liu C, Cheng X, Zhang S, Mao X, Qiu Y, et al. Identification of the Potential Key Circular RNAs in Elderly Patients With Postoperative Cognitive Dysfunction. Frontiers in Aging Neuroscience. 12: 165. PMID 32655392 DOI: 10.3389/Fnagi.2020.00165  0.341
2020 Panicker N, Kam T, Neifert S, Hinkle J, Mao X, Karuppagounder S, Wang H, Kumar M, Pirooznia S, Pletnikova O, Troncoso J, Dawson VL, Dawson TM. NLRP3 inflammasome activation in dopamine neurons contributes to neurodegeneration in Parkinson’s Disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01881  0.772
2019 Tang Y, Li X, Mao X. Editorial: Linking Neuroinflammation and Glial Phenotypic Changes in Neurological Diseases. Frontiers in Cellular Neuroscience. 13: 542. PMID 31920547 DOI: 10.3389/fncel.2019.00542  0.326
2019 Zhang L, Chen Q, Li P, Yuan L, Feng Y, Wang J, Mao X, Liu L. Deformation of stable and toxic hIAPP oligomers by liposomes with distinct nanomechanical features and reduced cytotoxicity. Chemical Communications (Cambridge, England). PMID 31720593 DOI: 10.1039/C9Cc06264E  0.446
2019 Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder SS, Ge P, Shi R, Kim EJ, Liu A, Kim D, Quintin S, Jiang H, Kumar M, Yun SP, Kam TI, ... Mao X, et al. Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease. Brain : a Journal of Neurology. PMID 31237944 DOI: 10.1093/Brain/Awz172  0.798
2019 Chen C, Gao R, Li M, Wang Q, Chen H, Zhang S, Mao X, Behensky A, Zhang Z, Gan L, Li T, Liao R, Li Q, Yu H, Yang J, et al. Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction. Brain, Behavior, and Immunity. PMID 30980952 DOI: 10.1016/J.Bbi.2019.04.024  0.36
2019 Willard AM, Isett BR, Whalen TC, Mastro KJ, Ki CS, Mao X, Gittis AH. State transitions in the substantia nigra reticulata predict the onset of motor deficits in models of progressive dopamine depletion in mice. Elife. 8. PMID 30839276 DOI: 10.7554/Elife.42746  0.362
2018 Wang T, Zhang L, Wang J, Feng Y, Xu E, Mao X, Liu L. Evaluation of the photo-degradation of Alzheimer's amyloid fibrils with a label-free approach. Chemical Communications (Cambridge, England). PMID 30394470 DOI: 10.1039/C8Cc07164K  0.424
2018 Kam TI, Mao X, Park H, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmachari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, et al. Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease. Science (New York, N.Y.). 362. PMID 30385548 DOI: 10.1126/Science.Aat8407  0.816
2018 Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, ... Mao X, et al. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease. Nature Medicine. PMID 29892066 DOI: 10.1038/S41591-018-0051-5  0.796
2018 Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, et al. Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29386392 DOI: 10.1073/Pnas.1712648115  0.781
2018 Kim S, Yun SP, Lee S, Umanah GE, Bandaru VVR, Yin X, Rhee P, Karuppagounder SS, Kwon SH, Lee H, Mao X, Kim D, Pandey A, Lee G, Dawson VL, et al. GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311330 DOI: 10.1073/Pnas.1700465115  0.822
2017 Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, et al. Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy. Stem Cell Reports. PMID 29337114 DOI: 10.1016/J.Stemcr.2017.12.001  0.719
2017 Umanah GKE, Pignatelli M, Yin X, Chen R, Crawford J, Neifert S, Scarffe L, Behensky AA, Guiberson N, Chang M, Ma E, Kim JW, Castro CC, Mao X, Chen L, et al. Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel. Science Translational Medicine. 9. PMID 29237760 DOI: 10.1126/Scitranslmed.Aah4985  0.624
2017 Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, et al. Erratum: T cells from patients with Parkinson's disease recognize α-synuclein peptides. Nature. 549: 292. PMID 28905919 DOI: 10.1038/nature23896  0.671
2017 Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, et al. T cells from patients with Parkinson's disease recognize α-synuclein peptides. Nature. PMID 28636593 DOI: 10.1038/Nature22815  0.707
2016 Zhang J, Wang H, Sherbini O, Ling-Lin Pai E, Kang SU, Kwon JS, Yang J, He W, Wang H, Eacker SM, Chi Z, Mao X, Xu J, Jiang H, Andrabi SA, et al. High-Content Genome-Wide RNAi Screen Reveals CCR3 as a Key Mediator of Neuronal Cell Death. Eneuro. 3. PMID 27822494 DOI: 10.1523/ENEURO.0185-16.2016  0.745
2016 Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, et al. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. Science (New York, N.Y.). 353. PMID 27708076 DOI: 10.1126/Science.Aah3374  0.786
2016 Brahmachari S, Ge P, Lee SH, Kim D, Karuppagounder SS, Kumar M, Mao X, Lee Y, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Ko HS. Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration. The Journal of Clinical Investigation. PMID 27348587 DOI: 10.1172/Jci85456  0.812
2013 Zhang M, Mao X, Yu Y, Wang CX, Yang YL, Wang C. Nanomaterials for reducing amyloid cytotoxicity. Advanced Materials (Deerfield Beach, Fla.). 25: 3780-801. PMID 23722464 DOI: 10.1002/Adma.201301210  0.391
2013 Mao X, Guo Y, Luo Y, Niu L, Liu L, Ma X, Wang H, Yang Y, Wei G, Wang C. Sequence effects on peptide assembly characteristics observed by using scanning tunneling microscopy. Journal of the American Chemical Society. 135: 2181-7. PMID 23331193 DOI: 10.1021/Ja307198U  0.362
2013 Zhang M, Mao X, Wang C, Zeng W, Zhang C, Li Z, Fang Y, Yang Y, Liang W, Wang C. The effect of graphene oxide on conformation change, aggregation and cytotoxicity of HIV-1 regulatory protein (Vpr). Biomaterials. 34: 1383-90. PMID 23153418 DOI: 10.1016/J.Biomaterials.2012.10.067  0.416
2012 Wang C, Yang A, Li X, Li D, Zhang M, Du H, Li C, Guo Y, Mao X, Dong M, Besenbacher F, Yang Y, Wang C. Observation of molecular inhibition and binding structures of amyloid peptides. Nanoscale. 4: 1895-909. PMID 22334382 DOI: 10.1039/C2Nr11508E  0.415
2011 Mao X, Guo Y, Wang C, Zhang M, Ma X, Liu L, Niu L, Zeng Q, Yang Y, Wang C. Binding modes of thioflavin T molecules to prion peptide assemblies identified by using scanning tunneling microscopy. Acs Chemical Neuroscience. 2: 281-7. PMID 22778872 DOI: 10.1021/Cn200006H  0.389
2011 Wang C, Mao X, Yang A, Niu L, Wang S, Li D, Guo Y, Wang Y, Yang Y, Wang C. Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy. Chemical Communications (Cambridge, England). 47: 10638-40. PMID 21869951 DOI: 10.1039/C1Cc12380G  0.331
2011 Liu L, Zhang L, Niu L, Xu M, Mao X, Yang Y, Wang C. Observation of reduced cytotoxicity of aggregated amyloidogenic peptides with chaperone-like molecules. Acs Nano. 5: 6001-7. PMID 21682328 DOI: 10.1021/Nn201773X  0.432
2011 He W, Hou S, Mao X, Wu X, Ji Y, Liu J, Hu X, Zhang K, Wang C, Yang Y, Wang Q. Peptide-tailored assembling of Au nanorods. Chemical Communications (Cambridge, England). 47: 5482-4. PMID 21483907 DOI: 10.1039/C1Cc10394F  0.351
2011 Mao X, Wang C, Ma X, Zhang M, Liu L, Zhang L, Niu L, Zeng Q, Yang Y, Wang C. Molecular level studies on binding modes of labeling molecules with polyalanine peptides. Nanoscale. 3: 1592-9. PMID 21283870 DOI: 10.1039/C0Nr00782J  0.344
2010 Yang M, Meng J, Mao X, Yang Y, Cheng X, Yuan H, Wang C, Xu H. Carbon nanotubes induce secondary structure changes of bovine albumin in aqueous phase. Journal of Nanoscience and Nanotechnology. 10: 7550-3. PMID 21137980 DOI: 10.1166/Jnn.2010.2825  0.336
2010 Niu L, Ma X, Liu L, Mao X, Wu D, Yang Y, Zeng Q, Wang C. Molecularly tuned peptide assemblies at the liquid-solid interface studied by scanning tunneling microscopy. Physical Chemistry Chemical Physics : Pccp. 12: 11683-7. PMID 20714468 DOI: 10.1039/B923927H  0.358
2010 Wang Y, Niu L, Li Y, Mao X, Yang Y, Wang C. Single molecule studies of cyclic peptides using molecular matrix at liquid/solid interface by scanning tunneling microscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 16305-11. PMID 20593799 DOI: 10.1021/La101467S  0.344
2010 Yang H, Mao X, Guo Y, Wang D, Ge G, Yang R, Qiu X, Yang Y, Wang C, Wang Y, Liu G. Porous α-Fe2O3 nanostructures with branched topology: growth, formation mechanism, and properties Crystengcomm. 12: 1842-1849. DOI: 10.1039/B921618A  0.466
2010 Zhou X, Yang H, Wang C, Mao X, Wang Y, Yang Y, Liu G. Visible Light Induced Photocatalytic Degradation of Rhodamine B on One-Dimensional Iron Oxide Particles The Journal of Physical Chemistry C. 114: 17051-17061. DOI: 10.1021/Jp103816E  0.462
2010 Mao X, Yang H, Zhou X, Wang C, Wang Y, Yang Y, Wang C, Liu G. Straight and Branched Goethite Topology by Oriented Attachment at High pH Crystal Growth & Design. 10: 504-509. DOI: 10.1021/Cg900392M  0.319
2009 Liu L, Zhang L, Mao X, Niu L, Yang Y, Wang C. Chaperon-mediated single molecular approach toward modulating Abeta peptide aggregation. Nano Letters. 9: 4066-72. PMID 19842691 DOI: 10.1021/Nl902256B  0.395
2009 Mao X, Wang Y, Liu L, Niu L, Yang Y, Wang C. Molecular-level evidence of the surface-induced transformation of peptide structures revealed by scanning tunneling microscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 8849-53. PMID 19624165 DOI: 10.1021/La901342R  0.351
2009 Mao X, Ma X, Liu L, Niu L, Yang Y, Wang C. Structural characteristics of the beta-sheet-like human and rat islet amyloid polypeptides as determined by scanning tunneling microscopy. Journal of Structural Biology. 167: 209-15. PMID 19505580 DOI: 10.1016/J.Jsb.2009.05.009  0.36
2009 Ma X, Liu L, Mao X, Niu L, Deng K, Wu W, Li Y, Yang Y, Wang C. Amyloid beta (1-42) folding multiplicity and single-molecule binding behavior studied with STM. Journal of Molecular Biology. 388: 894-901. PMID 19328210 DOI: 10.1016/J.Jmb.2009.03.054  0.395
2008 Mao X, Ma Z, Yang Y, Lei S, Wang C, Huang W. Self-assembly of truxene derivatives investigated by STM Frontiers of Materials Science in China. 2: 26-30. DOI: 10.1007/S11706-008-0005-9  0.347
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