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Year Citation  Score
2020 Bock C, Boutros M, Camp JG, Clarke L, Clevers H, Knoblich JA, Liberali P, Regev A, Rios AC, Stegle O, Stunnenberg HG, Teichmann SA, Treutlein B, Vries RGJ. The Organoid Cell Atlas. Nature Biotechnology. PMID 33384458 DOI: 10.1038/s41587-020-00762-x  0.324
2020 Bonnay F, Veloso A, Steinmann V, Köcher T, Abdusselamoglu MD, Bajaj S, Rivelles E, Landskron L, Esterbauer H, Zinzen RP, Knoblich JA. Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis. Cell. 182: 1490-1507.e19. PMID 32916131 DOI: 10.1016/J.Cell.2020.07.039  0.635
2020 Kim J, Koo BK, Knoblich JA. Human organoids: model systems for human biology and medicine. Nature Reviews. Molecular Cell Biology. PMID 32636524 DOI: 10.1038/S41580-020-0259-3  0.586
2020 Sidhaye J, Knoblich JA. Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease. Cell Death and Differentiation. PMID 32483384 DOI: 10.1038/S41418-020-0566-4  0.616
2020 Bonnay F, Knoblich JA. Prospero Phase-Separating the Way to Neuronal Differentiation. Developmental Cell. 52: 251-252. PMID 32049033 DOI: 10.1016/J.Devcel.2020.01.022  0.624
2019 Abdusselamoglu MD, Landskron L, Bowman SK, Eroglu E, Burkard T, Kingston RE, Knoblich JA. Dynamics of activating and repressive histone modifications in neural stem cell lineages and brain tumors. Development (Cambridge, England). PMID 31748204 DOI: 10.1242/Dev.183400  0.657
2019 Abdusselamoglu MD, Eroglu E, Burkard TR, Knoblich JA. The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop. Elife. 8. PMID 31329099 DOI: 10.7554/Elife.46566  0.598
2019 Masselink W, Reumann D, Murawala P, Pasierbek P, Taniguchi Y, Bonnay F, Meixner K, Knoblich JA, Tanaka EM. Broad applicability of a streamlined Ethyl Cinnamate-based clearing procedure. Development (Cambridge, England). PMID 30665888 DOI: 10.1242/dev.166884  0.508
2018 Lancaster MA, Corsini NS, Wolfinger S, Gustafson EH, Phillips AW, Burkard TR, Otani T, Livesey FJ, Knoblich JA. Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids. Nature Biotechnology. 36: 1016. PMID 30307926 DOI: 10.1038/Nbt1018-1016A  0.725
2018 Wissel S, Harzer H, Bonnay F, Burkard TR, Neumüller RA, Knoblich JA. Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop. The Journal of Cell Biology. PMID 29959232 DOI: 10.1083/Jcb.201711167  0.703
2018 Corsini NS, Peer AM, Moeseneder P, Roiuk M, Burkard TR, Theussl HC, Moll I, Knoblich JA. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 22: 543-558.e12. PMID 29625069 DOI: 10.1016/J.Stem.2018.03.002  0.637
2018 Corsini NS, Knoblich JA. Tracing Stem Cell Division in Adult Neurogenesis. Cell Stem Cell. 22: 143-145. PMID 29451854 DOI: 10.1016/J.Stem.2018.01.012  0.669
2018 Reichardt I, Bonnay F, Steinmann V, Loedige I, Burkard TR, Meister G, Knoblich JA. The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda. Embo Reports. 19: 102-117. PMID 29191977 DOI: 10.15252/Embr.201744188  0.644
2018 Zhang J, Ooi J, Langley SR, Aning OA, Renner M, Cheok CF, Petretto E, Knoblich JA, Pouladi MA. A48 Expanded HTT cag repeats disrupt the balance between neural progenitor expansion and differentiation in isogenic human cerebral organoids Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.46  0.428
2017 Abramczuk MK, Burkard TR, Rolland V, Steinmann V, Duchek P, Jiang Y, Wissel S, Reichert H, Knoblich JA. The splicing co-factor Barricade/Tat-SF1, is required for cell cycle and lineage progression in Drosophila neural stem cells. Development (Cambridge, England). PMID 28935704 DOI: 10.1242/Dev.152199  0.705
2017 Lancaster MA, Corsini NS, Wolfinger S, Gustafson EH, Phillips AW, Burkard TR, Otani T, Livesey FJ, Knoblich JA. Guided self-organization and cortical plate formation in human brain organoids. Nature Biotechnology. PMID 28562594 DOI: 10.1038/Nbt.3906  0.759
2017 Bagley JA, Reumann D, Bian S, Lévi-Strauss J, Knoblich JA. Fused cerebral organoids model interactions between brain regions. Nature Methods. PMID 28504681 DOI: 10.1038/Nmeth.4304  0.605
2017 Huch M, Knoblich JA, Lutolf MP, Martinez-Arias A. The hope and the hype of organoid research. Development (Cambridge, England). 144: 938-941. PMID 28292837 DOI: 10.1242/Dev.150201  0.528
2017 Renner M, Lancaster MA, Bian S, Choi H, Ku T, Peer A, Chung K, Knoblich JA. Self-organized developmental patterning and differentiation in cerebral organoids. The Embo Journal. PMID 28283582 DOI: 10.15252/Embj.201694700  0.752
2017 Bredenoord AL, Clevers H, Knoblich JA. Human tissues in a dish: The research and ethical implications of organoid technology. Science (New York, N.Y.). 355. PMID 28104841 DOI: 10.1126/Science.Aaf9414  0.574
2016 Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R. Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. PMID 28041895 DOI: 10.1016/J.Stem.2016.11.017  0.751
2016 Luo C, Lancaster MA, Castanon R, Nery JR, Knoblich JA, Ecker JR. Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain. Cell Reports. 17: 3369-3384. PMID 28009303 DOI: 10.1016/J.Celrep.2016.12.001  0.744
2016 Knoblich JA. Lab-Built Brains. Scientific American. 316: 26-31. PMID 28004710 DOI: 10.1038/Scientificamerican0117-26  0.549
2016 Fededa JP, Esk C, Mierzwa B, Stanyte R, Yuan S, Zheng H, Ebnet K, Yan W, Knoblich JA, Gerlich DW. MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. The Embo Journal. PMID 27707753 DOI: 10.15252/Embj.201694056  0.607
2016 Landskron L, Knoblich JA. You Are What You Eat: Linking Metabolic Asymmetry and Cell Fate Choice. Developmental Cell. 37: 206-8. PMID 27165551 DOI: 10.1016/J.Devcel.2016.04.017  0.626
2015 Camp JG, Badsha F, Florio M, Kanton S, Gerber T, Wilsch-Bräuninger M, Lewitus E, Sykes A, Hevers W, Lancaster M, Knoblich JA, Lachmann R, Pääbo S, Huttner WB, Treutlein B. Human cerebral organoids recapitulate gene expression programs of fetal neocortex development. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644564 DOI: 10.1073/Pnas.1520760112  0.784
2015 Ballard MS, Zhu A, Iwai N, Stensrud M, Mapps A, Postiglione MP, Knoblich JA, Hinck L. Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC. Cell Reports. 13: 290-301. PMID 26440891 DOI: 10.1016/J.Celrep.2015.09.006  0.688
2015 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, ... ... Knoblich J, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/Science.Aac7932  0.738
2014 Marchetti G, Reichardt I, Knoblich JA, Besse F. The TRIM-NHL protein Brat promotes axon maintenance by repressing src64B expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 13855-64. PMID 25297111 DOI: 10.1523/Jneurosci.3285-13.2014  0.589
2014 Lancaster MA, Knoblich JA. Generation of cerebral organoids from human pluripotent stem cells. Nature Protocols. 9: 2329-40. PMID 25188634 DOI: 10.1038/Nprot.2014.158  0.757
2014 Homem CC, Steinmann V, Burkard TR, Jais A, Esterbauer H, Knoblich JA. Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell. 158: 874-88. PMID 25126791 DOI: 10.1016/J.Cell.2014.06.024  0.682
2014 Mauri F, Reichardt I, Mummery-Widmer JL, Yamazaki M, Knoblich JA. The conserved discs-large binding partner Banderuola regulates asymmetric cell division in Drosophila. Current Biology : Cb. 24: 1811-25. PMID 25088559 DOI: 10.1016/j.cub.2014.06.059  0.673
2014 Lancaster MA, Knoblich JA. Organogenesis in a dish: modeling development and disease using organoid technologies. Science (New York, N.Y.). 345: 1247125. PMID 25035496 DOI: 10.1126/Science.1247125  0.778
2014 Williams SE, Ratliff LA, Postiglione MP, Knoblich JA, Fuchs E. Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN. Nature Cell Biology. 16: 758-69. PMID 25016959 DOI: 10.1038/Ncb3001  0.687
2014 Ayukawa T, Akiyama M, Mummery-Widmer JL, Stoeger T, Sasaki J, Knoblich JA, Senoo H, Sasaki T, Yamazaki M. Dachsous-dependent asymmetric localization of spiny-legs determines planar cell polarity orientation in Drosophila. Cell Reports. 8: 610-21. PMID 24998533 DOI: 10.1016/J.Celrep.2014.06.009  0.628
2014 Yasugi T, Fischer A, Jiang Y, Reichert H, Knoblich JA. A regulatory transcriptional loop controls proliferation and differentiation in Drosophila neural stem cells. Plos One. 9: e97034. PMID 24804774 DOI: 10.1371/Journal.Pone.0097034  0.674
2014 Eroglu E, Burkard TR, Jiang Y, Saini N, Homem CC, Reichert H, Knoblich JA. SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells. Cell. 156: 1259-73. PMID 24630726 DOI: 10.1016/J.Cell.2014.01.053  0.652
2014 Jüschke C, Xie Y, Postiglione MP, Knoblich JA. Analysis and modeling of mitotic spindle orientations in three dimensions. Proceedings of the National Academy of Sciences of the United States of America. 111: 1014-9. PMID 24381158 DOI: 10.1073/Pnas.1314984111  0.61
2013 Jüschke C, Dohnal I, Pichler P, Harzer H, Swart R, Ammerer G, Mechtler K, Knoblich JA. Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biology. 14: r133. PMID 24289286 DOI: 10.1186/Gb-2013-14-11-R133  0.61
2013 Homem CC, Reichardt I, Berger C, Lendl T, Knoblich JA. Long-term live cell imaging and automated 4D analysis of drosophila neuroblast lineages. Plos One. 8: e79588. PMID 24260257 DOI: 10.1371/Journal.Pone.0079588  0.661
2013 Lancaster MA, Renner M, Martin CA, Wenzel D, Bicknell LS, Hurles ME, Homfray T, Penninger JM, Jackson AP, Knoblich JA. Cerebral organoids model human brain development and microcephaly. Nature. 501: 373-9. PMID 23995685 DOI: 10.1038/Nature12517  0.774
2013 Bardet AF, Steinmann J, Bafna S, Knoblich JA, Zeitlinger J, Stark A. Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics (Oxford, England). 29: 2705-13. PMID 23980024 DOI: 10.1093/Bioinformatics/Btt470  0.56
2013 Xie Y, Jüschke C, Esk C, Hirotsune S, Knoblich JA. The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron. 79: 254-65. PMID 23830831 DOI: 10.1016/J.Neuron.2013.05.027  0.685
2013 Harzer H, Berger C, Conder R, Schmauss G, Knoblich JA. FACS purification of Drosophila larval neuroblasts for next-generation sequencing. Nature Protocols. 8: 1088-99. PMID 23660757 DOI: 10.1038/Nprot.2013.062  0.685
2013 Sparmann A, Xie Y, Verhoeven E, Vermeulen M, Lancini C, Gargiulo G, Hulsman D, Mann M, Knoblich JA, van Lohuizen M. The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. The Embo Journal. 32: 1598-612. PMID 23624931 DOI: 10.1038/Emboj.2013.93  0.675
2012 Homem CC, Knoblich JA. Drosophila neuroblasts: a model for stem cell biology. Development (Cambridge, England). 139: 4297-310. PMID 23132240 DOI: 10.1242/Dev.080515  0.692
2012 Goulas S, Conder R, Knoblich JA. The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells. Cell Stem Cell. 11: 529-40. PMID 23040479 DOI: 10.1016/J.Stem.2012.06.017  0.698
2012 Berger C, Harzer H, Burkard TR, Steinmann J, van der Horst S, Laurenson AS, Novatchkova M, Reichert H, Knoblich JA. FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Cell Reports. 2: 407-18. PMID 22884370 DOI: 10.1016/J.Celrep.2012.07.008  0.684
2012 Lancaster MA, Knoblich JA. Spindle orientation in mammalian cerebral cortical development. Current Opinion in Neurobiology. 22: 737-46. PMID 22554882 DOI: 10.1016/J.Conb.2012.04.003  0.797
2012 Postiglione MP, Xie Y, Jüschke C, Haas GA, Charalambous C, Knoblich JA. ISDN2012_0274: The orientation of asymmetric cell divisions directs lineage decisions in the mouse neocortex International Journal of Developmental Neuroscience. 30: 637-637. DOI: 10.1016/J.Ijdevneu.2012.10.096  0.622
2011 Postiglione MP, Jüschke C, Xie Y, Haas GA, Charalambous C, Knoblich JA. Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 72: 269-84. PMID 22017987 DOI: 10.1016/J.Neuron.2011.09.022  0.657
2011 Richter C, Oktaba K, Steinmann J, Müller J, Knoblich JA. The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. Nature Cell Biology. 13: 1029-39. PMID 21857667 DOI: 10.1038/Ncb2306  0.608
2011 Neumüller RA, Richter C, Fischer A, Novatchkova M, Neumüller KG, Knoblich JA. Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8: 580-93. PMID 21549331 DOI: 10.1016/J.Stem.2011.02.022  0.658
2010 Knoblich JA. Asymmetric cell division: recent developments and their implications for tumour biology. Nature Reviews. Molecular Cell Biology. 11: 849-60. PMID 21102610 DOI: 10.1038/Nrm3010  0.679
2009 Neumüller RA, Knoblich JA. Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes & Development. 23: 2675-99. PMID 19952104 DOI: 10.1101/Gad.1850809  0.692
2009 Conder R, Knoblich JA. Fly stem cell research gets infectious. Cell. 137: 1185-7. PMID 19563751 DOI: 10.1016/J.Cell.2009.06.006  0.634
2009 Neumüller RA, Knoblich JA. Wicked views on stem cell news. Nature Cell Biology. 11: 678-9. PMID 19488057 DOI: 10.1038/Ncb0609-678  0.673
2009 Mummery-Widmer JL, Yamazaki M, Stoeger T, Novatchkova M, Bhalerao S, Chen D, Dietzl G, Dickson BJ, Knoblich JA. Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature. 458: 987-92. PMID 19363474 DOI: 10.1038/Nature07936  0.61
2009 Coumailleau F, Fürthauer M, Knoblich JA, González-Gaitán M. Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature. 458: 1051-5. PMID 19295516 DOI: 10.1038/Nature07854  0.621
2009 Schwamborn JC, Berezikov E, Knoblich JA. The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell. 136: 913-25. PMID 19269368 DOI: 10.1016/J.Cell.2008.12.024  0.696
2009 Mauri F, Stoeger T, Mummery-Widmer J, Yamazaki M, Knoblich J. 02-P011 Identification of new cell growth regulators in Drosophila melanogaster by genome wide RNAi screening Mechanisms of Development. 126: S63. DOI: 10.1016/J.Mod.2009.06.041  0.585
2008 Wirtz-Peitz F, Nishimura T, Knoblich JA. Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell. 135: 161-73. PMID 18854163 DOI: 10.1016/J.Cell.2008.07.049  0.662
2008 Neumüller RA, Betschinger J, Fischer A, Bushati N, Poernbacher I, Mechtler K, Cohen SM, Knoblich JA. Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature. 454: 241-5. PMID 18528333 DOI: 10.1038/Nature07014  0.691
2008 Speicher S, Fischer A, Knoblich J, Carmena A. The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors. Current Biology : Cb. 18: 831-7. PMID 18499457 DOI: 10.1016/J.Cub.2008.04.072  0.698
2008 Schwamborn JC, Knoblich JA. LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell. 2: 193-4. PMID 18371441 DOI: 10.1016/J.Stem.2008.02.010  0.685
2008 Bowman SK, Rolland V, Betschinger J, Kinsey KA, Emery G, Knoblich JA. The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Developmental Cell. 14: 535-46. PMID 18342578 DOI: 10.1016/J.Devcel.2008.03.004  0.661
2008 Knoblich JA. Mechanisms of asymmetric stem cell division. Cell. 132: 583-97. PMID 18295577 DOI: 10.1016/J.Cell.2008.02.007  0.694
2007 Knoblich J. On the backroads to cellular asymmetry Development. 134: 4311-4313. DOI: 10.1242/Dev.014886  0.672
2006 Knoblich JA. Cell biology. Sara splits the signal. Science (New York, N.Y.). 314: 1094-6. PMID 17110561 DOI: 10.1126/Science.1135825  0.624
2006 Gallagher CM, Knoblich JA. The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Developmental Cell. 11: 641-53. PMID 17084357 DOI: 10.1016/J.Devcel.2006.09.014  0.674
2006 Hutterer A, Berdnik D, Wirtz-Peitz F, Zigman M, Schleiffer A, Knoblich JA. Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Developmental Cell. 11: 147-57. PMID 16890155 DOI: 10.1016/J.Devcel.2006.06.002  0.628
2006 Emery G, Knoblich JA. Endosome dynamics during development. Current Opinion in Cell Biology. 18: 407-15. PMID 16806877 DOI: 10.1016/J.Ceb.2006.06.009  0.654
2006 Bowman SK, Neumüller RA, Novatchkova M, Du Q, Knoblich JA. The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Developmental Cell. 10: 731-42. PMID 16740476 DOI: 10.1016/J.Devcel.2006.05.005  0.666
2006 Wirtz-Peitz F, Knoblich JA. Lethal giant larvae take on a life of their own. Trends in Cell Biology. 16: 234-41. PMID 16616850 DOI: 10.1016/J.Tcb.2006.03.006  0.621
2006 Betschinger J, Mechtler K, Knoblich JA. Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell. 124: 1241-53. PMID 16564014 DOI: 10.1016/J.Cell.2006.01.038  0.692
2005 Knoblich JA. Pins for spines. Nature Cell Biology. 7: 1157-8. PMID 16319966 DOI: 10.1038/ncb1205-1057  0.461
2005 Zigman M, Cayouette M, Charalambous C, Schleiffer A, Hoeller O, Dunican D, McCudden CR, Firnberg N, Barres BA, Siderovski DP, Knoblich JA. Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron. 48: 539-45. PMID 16301171 DOI: 10.1016/J.Neuron.2005.09.030  0.669
2005 Mayer B, Emery G, Berdnik D, Wirtz-Peitz F, Knoblich JA. Quantitative analysis of protein dynamics during asymmetric cell division. Current Biology : Cb. 15: 1847-54. PMID 16243032 DOI: 10.1016/J.Cub.2005.08.067  0.674
2005 Hampoelz B, Hoeller O, Bowman SK, Dunican D, Knoblich JA. Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins. Nature Cell Biology. 7: 1099-105. PMID 16228011 DOI: 10.1038/Ncb1318  0.635
2005 Bhalerao S, Berdnik D, Török T, Knoblich JA. Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila. Current Biology : Cb. 15: 1583-90. PMID 16139215 DOI: 10.1016/J.Cub.2005.07.061  0.686
2005 Jafar-Nejad H, Andrews HK, Acar M, Bayat V, Wirtz-Peitz F, Mehta SQ, Knoblich JA, Bellen HJ. Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Developmental Cell. 9: 351-63. PMID 16137928 DOI: 10.1016/J.Devcel.2005.06.010  0.644
2005 Emery G, Hutterer A, Berdnik D, Mayer B, Wirtz-Peitz F, Gaitan MG, Knoblich JA. Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell. 122: 763-73. PMID 16137758 DOI: 10.1016/J.Cell.2005.08.017  0.696
2005 Hutterer A, Knoblich JA. Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. Embo Reports. 6: 836-42. PMID 16113648 DOI: 10.1038/Sj.Embor.7400500  0.671
2005 Knoblich JA. Neurobiology: getting axons going. Nature. 436: 632-3. PMID 16079825 DOI: 10.1038/436632A  0.547
2005 Betschinger J, Eisenhaber F, Knoblich JA. Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Current Biology : Cb. 15: 276-82. PMID 15694314 DOI: 10.1016/J.Cub.2005.01.012  0.645
2005 Zarnescu DC, Jin P, Betschinger J, Nakamoto M, Wang Y, Dockendorff TC, Feng Y, Jongens TA, Sisson JC, Knoblich JA, Warren ST, Moses K. Fragile X protein functions with lgl and the par complex in flies and mice. Developmental Cell. 8: 43-52. PMID 15621528 DOI: 10.1016/J.Devcel.2004.10.020  0.598
2004 Hampoelz B, Knoblich JA. Heterotrimeric G proteins: new tricks for an old dog. Cell. 119: 453-6. PMID 15537535 DOI: 10.1016/J.Cell.2004.10.025  0.604
2004 Hutterer A, Betschinger J, Petronczki M, Knoblich JA. Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Developmental Cell. 6: 845-54. PMID 15177032 DOI: 10.1016/J.Devcel.2004.05.003  0.665
2003 Subramanian A, Prokop A, Yamamoto M, Sugimura K, Uemura T, Betschinger J, Knoblich JA, Volk T. Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Current Biology : Cb. 13: 1086-95. PMID 12842007 DOI: 10.1016/S0960-9822(03)00416-0  0.725
2003 Blumer JB, Bernard ML, Peterson YK, Nezu J, Chung P, Dunican DJ, Knoblich JA, Lanier SM. Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha. The Journal of Biological Chemistry. 278: 23217-20. PMID 12719437 DOI: 10.1074/Jbc.C200686200  0.593
2003 Betschinger J, Mechtler K, Knoblich JA. The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature. 422: 326-30. PMID 12629552 DOI: 10.1038/Nature01486  0.679
2003 Knoblich JA. Genetic Analysis of Heterotrimeric G-Protein Function Handbook of Cell Signaling. 2: 571-573. DOI: 10.1016/B978-012124546-7/50575-1  0.511
2002 Berdnik D, Török T, González-Gaitán M, Knoblich JA. The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Developmental Cell. 3: 221-31. PMID 12194853 DOI: 10.1016/S1534-5807(02)00215-0  0.657
2002 Berdnik D, Knoblich JA. Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Current Biology : Cb. 12: 640-7. PMID 11967150 DOI: 10.1016/S0960-9822(02)00766-2  0.683
2001 Schaefer M, Knoblich JA. Protein localization during asymmetric cell division. Experimental Cell Research. 271: 66-74. PMID 11697883 DOI: 10.1006/Excr.2001.5371  0.656
2001 Schaefer M, Petronczki M, Dorner D, Forte M, Knoblich JA. Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell. 107: 183-94. PMID 11672526 DOI: 10.1016/S0092-8674(01)00521-9  0.636
2001 Huynh JR, Petronczki M, Knoblich JA, St Johnston D. Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila. Current Biology : Cb. 11: 901-6. PMID 11516655 DOI: 10.1016/S0960-9822(01)00244-5  0.655
2001 Knoblich JA. Asymmetric cell division during animal development. Nature Reviews. Molecular Cell Biology. 2: 11-20. PMID 11413461 DOI: 10.1038/35048085  0.701
2001 Petronczki M, Knoblich JA. DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila. Nature Cell Biology. 3: 43-9. PMID 11146625 DOI: 10.1038/35050550  0.702
2000 Knoblich JA. Epithelial polarity: the ins and outs of the fly epidermis. Current Biology : Cb. 10: R791-4. PMID 11084352 DOI: 10.1016/S0960-9822(00)00761-2  0.622
2000 Schaefer M, Shevchenko A, Shevchenko A, Knoblich JA. A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila. Current Biology : Cb. 10: 353-62. PMID 10753746 DOI: 10.1016/S0960-9822(00)00401-2  0.675
1999 Schober M, Schaefer M, Knoblich JA. Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature. 402: 548-51. PMID 10591217 DOI: 10.1038/990135  0.693
1999 Knoblich JA, Jan LY, Jan YN. Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization. Current Biology : Cb. 9: 155-8. PMID 10021388 DOI: 10.1016/S0960-9822(99)80070-0  0.709
1998 Shen CP, Knoblich JA, Chan YM, Jiang MM, Jan LY, Jan YN. Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila. Genes & Development. 12: 1837-46. PMID 9637685 DOI: 10.1101/Gad.12.12.1837  0.737
1997 Knoblich JA, Jan LY, Jan YN. Asymmetric segregation of the Drosophila numb protein during mitosis: facts and speculations. Cold Spring Harbor Symposia On Quantitative Biology. 62: 71-7. PMID 9598338 DOI: 10.1101/Sqb.1997.062.01.011  0.677
1997 Knoblich JA. Mechanisms of asymmetric cell division during animal development. Current Opinion in Cell Biology. 9: 833-41. PMID 9425348 DOI: 10.1016/S0955-0674(97)80085-3  0.705
1997 Knoblich JA, Jan LY, Jan YN. The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proceedings of the National Academy of Sciences of the United States of America. 94: 13005-10. PMID 9371790 DOI: 10.1073/Pnas.94.24.13005  0.701
1994 Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77: 107-20. PMID 8156587 DOI: 10.1016/0092-8674(94)90239-9  0.775
1993 Knoblich JA, Lehner CF. Synergistic action of Drosophila cyclins A and B during the G2-M transition. The Embo Journal. 12: 65-74. PMID 8428595 DOI: 10.1002/J.1460-2075.1993.Tb05632.X  0.721
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