☰

Joseph A. Sorg, Ph.D. - Publications

Affiliations: 
2001-2006 Microbiology University of Chicago, Chicago, IL 
Area:
Microbiology Biology, Molecular Biology
Tree Info Similar researchers PubMed Report error

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nerber HN, Baloh M, Sorg JA. The small acid-soluble proteins of regulate sporulation in a SpoIVB2-dependent manner. Biorxiv : the Preprint Server For Biology. PMID 37292792 DOI: 10.1101/2023.05.17.541253  0.807
2022 Aguirre AM, Adegbite AO, Sorg JA. Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation. Npj Biofilms and Microbiomes. 8: 94. PMID 36450806 DOI: 10.1038/s41522-022-00358-0  0.818
2022 Aguirre AM, Sorg JA. Gut associated metabolites and their roles in pathogenesis. Gut Microbes. 14: 2094672. PMID 35793402 DOI: 10.1080/19490976.2022.2094672  0.782
2022 Baloh M, Nerber HN, Sorg JA. Imaging Clostridioides difficile Spore Germination and Germination Proteins. Journal of Bacteriology. e0021022. PMID 35762766 DOI: 10.1128/jb.00210-22  0.816
2022 Simeon RA, Zeng Y, Chonira V, Aguirre AM, Lasagna M, Baloh M, Sorg JA, Tommos C, Chen Z. Correction to: Protease-stable DARPins as promising oral therapeutics. Protein Engineering, Design & Selection : Peds. PMID 35368085 DOI: 10.1093/protein/gzac003  0.731
2021 Simeon RA, Zeng Y, Chonira V, Aguirre AM, Lasagna M, Baloh M, Sorg JA, Tommos C, Chen Z. Protease-stable DARPins as promising oral therapeutics. Protein Engineering, Design & Selection : Peds. 34. PMID 34882774 DOI: 10.1093/protein/gzab028  0.759
2021 Baloh M, Sorg JA. Clostridioides difficile spore germination: initiation to DPA release. Current Opinion in Microbiology. 65: 101-107. PMID 34808546 DOI: 10.1016/j.mib.2021.11.001  0.812
2021 Aguirre AM, Yalcinkaya N, Wu Q, Swennes A, Tessier ME, Roberts P, Miyajima F, Savidge T, Sorg JA. Bile acid-independent protection against Clostridioides difficile infection. Plos Pathogens. 17: e1010015. PMID 34665847 DOI: 10.1371/journal.ppat.1010015  0.817
2021 Nerber HN, Sorg JA. The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation. Plos Pathogens. 17: e1009516. PMID 34496003 DOI: 10.1371/journal.ppat.1009516  0.344
2021 Baloh M, Sorg JA. SpoVAD and SpoVAE interact and are required for DPA uptake into spores. Journal of Bacteriology. JB0039421. PMID 34424035 DOI: 10.1128/JB.00394-21  0.779
2021 McAllister KN, Martinez Aguirre A, Sorg JA. The selenophosphate synthetase, , is important for physiology. Journal of Bacteriology. PMID 33820795 DOI: 10.1128/JB.00008-21  0.804
2020 Engevik MA, Danhof HA, Shrestha R, Chang-Graham AL, Hyser JM, Haag AM, Mohammad MA, Britton RA, Versalovic J, Sorg JA, Spinler JK. Reuterin disrupts metabolism and pathogenicity through reactive oxygen species generation. Gut Microbes. 12: 1788898. PMID 32804011 DOI: 10.1080/19490976.2020.1795388  0.788
2020 Bhattacharjee D, Sorg JA. Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains. Msphere. 5. PMID 32132157 DOI: 10.1128/mSphere.00941-19  0.769
2019 McAllister KN, Sorg JA. CRISPR genome editing systems in the genus : a timely advancement. Journal of Bacteriology. PMID 31085694 DOI: 10.1128/Jb.00219-19  0.756
2019 Shrestha R, Cochran AM, Sorg JA. The requirement for co-germinants during C. difficile spore germination is influenced by mutations in yabG and cspA. Plos Pathogens. 15: e1007681. PMID 30943268 DOI: 10.1371/Journal.Ppat.1007681  0.79
2019 Shrestha R, Sorg JA. Terbium chloride influences Clostridium difficile spore germination. Anaerobe. PMID 30926439 DOI: 10.1016/J.Anaerobe.2019.03.016  0.8
2019 Bouillaut L, Dubois T, Francis MB, Daou N, Monot M, Sorg JA, Sonenshein AL, Dupuy B. Role of the Global Regulator Rex in Control of NAD -Regeneration in Clostridioides (Clostridium) difficile. Molecular Microbiology. PMID 30882947 DOI: 10.1111/Mmi.14245  0.785
2019 Savidge T, Sorg JA. Role of Bile in Infectious Disease: the Gall of 7α-Dehydroxylating Gut Bacteria. Cell Chemical Biology. 26: 1-3. PMID 30658109 DOI: 10.1016/J.Chembiol.2018.12.010  0.413
2018 Bhattacharjee D, Sorg JA. Conservation of the "Outside-in" Germination Pathway in . Frontiers in Microbiology. 9: 2487. PMID 30386321 DOI: 10.3389/Fmicb.2018.02487  0.825
2018 Zhu D, Sorg JA, Sun X. Biology: Sporulation, Germination, and Corresponding Therapies forInfection. Frontiers in Cellular and Infection Microbiology. 8: 29. PMID 29473021 DOI: 10.3389/Fcimb.2018.00029  0.489
2017 Shrestha R, Sorg JA. Hierarchical recognition of amino acid co-germinants during Clostridioides difficile spore germination. Anaerobe. 49: 41-47. PMID 29221987 DOI: 10.1016/J.Anaerobe.2017.12.001  0.803
2017 McAllister KN, Bouillaut L, Kahn JN, Self WT, Sorg JA. Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis. Scientific Reports. 7: 14672. PMID 29116155 DOI: 10.1038/S41598-017-15236-5  0.8
2017 Shrestha R, Lockless SW, Sorg JA. A Clostridium difficile alanine racemase affects spore germination and accommodates serine as a substrate. The Journal of Biological Chemistry. PMID 28487371 DOI: 10.1074/Jbc.M117.791749  0.806
2017 Girinathan BP, Monot M, Boyle D, McAllister KN, Sorg JA, Dupuy B, Govind R. Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291. Msphere. 2. PMID 28217744 DOI: 10.1128/mSphere.00383-16  0.812
2016 Francis MB, Sorg JA. Dipicolinic Acid Release by Germinating Clostridium difficile Spores Occurs through a Mechanosensing Mechanism. Msphere. 1. PMID 27981237 DOI: 10.1128/mSphere.00306-16  0.725
2016 Bhattacharjee D, McAllister KN, Sorg JA. Germinants and their receptors in clostridia. Journal of Bacteriology. PMID 27432831 DOI: 10.1128/Jb.00405-16  0.779
2016 Francis MB, Sorg JA. Detecting Cortex Fragments During Bacterial Spore Germination. Journal of Visualized Experiments : Jove. PMID 27403726 DOI: 10.3791/54146  0.688
2015 Bhattacharjee D, Francis MB, Ding X, McAllister KN, Shrestha R, Sorg JA. Re-examining the germination phenotypes of several Clostridium difficile strains suggests another role for the CspC germinant receptor. Journal of Bacteriology. PMID 26668265 DOI: 10.1128/Jb.00908-15  0.777
2015 Fimlaid KA, Jensen O, Donnelly ML, Francis MB, Sorg JA, Shen A. Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination. Plos Pathogens. 11: e1005239. PMID 26496694 DOI: 10.1371/Journal.Ppat.1005239  0.744
2015 Bouillaut L, McBride S, Sorg JA, Schmidt DJ, Suarez JM, Tzipori S, Mascio C, Chesnel L, Sonenshein AL. Effects of surotomycin on Clostridium difficile viability and toxin production in vitro. Antimicrobial Agents and Chemotherapy. 59: 4199-205. PMID 25941230 DOI: 10.1128/Aac.00275-15  0.721
2015 Francis MB, Allen CA, Sorg JA. Spore Cortex Hydrolysis Precedes Dipicolinic Acid Release during Clostridium difficile Spore Germination. Journal of Bacteriology. 197: 2276-83. PMID 25917906 DOI: 10.1128/Jb.02575-14  0.696
2015 Bouillaut L, McBride S, Sorg JA, Schmidt DJ, Suarez JM, Tzipori S, Mascio C, Chesnel L, Sonenshein AL. Effects of surotomycin on Clostridium difficile viability and toxin production in vitro Antimicrobial Agents and Chemotherapy. 59: 4199-4205. DOI: 10.1128/AAC.00275-15  0.671
2015 Tessier MEM, Andersson H, Ross C, Peniche-trujillo A, Dann S, Francis M, Sorg J, Thevananther S, Conner ME, Savidge T. Mo1850 Obeticholic Acid (INT-747) Confers Disease Protection Against Clostridium difficile Infection Gastroenterology. 148: S-726. DOI: 10.1016/S0016-5085(15)32479-3  0.367
2014 Sorg JA. Microbial bile acid metabolic clusters: the bouncers at the bar. Cell Host & Microbe. 16: 551-2. PMID 25525784 DOI: 10.1016/J.Chom.2014.10.015  0.363
2014 Paredes-Sabja D, Shen A, Sorg JA. Clostridium difficile spore biology: sporulation, germination, and spore structural proteins. Trends in Microbiology. 22: 406-16. PMID 24814671 DOI: 10.1016/J.Tim.2014.04.003  0.472
2013 Francis MB, Allen CA, Sorg JA. Muricholic acids inhibit Clostridium difficile spore germination and growth. Plos One. 8: e73653. PMID 24040011 DOI: 10.1371/Journal.Pone.0073653  0.737
2013 Francis MB, Allen CA, Shrestha R, Sorg JA. Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection. Plos Pathogens. 9: e1003356. PMID 23675301 DOI: 10.1371/Journal.Ppat.1003356  0.83
2013 Chen S, Wilson-Stanford S, Cromwell W, Hillman JD, Guerrero A, Allen CA, Sorg JA, Smith L. Site-directed mutations in the lanthipeptide mutacin 1140. Applied and Environmental Microbiology. 79: 4015-23. PMID 23603688 DOI: 10.1128/Aem.00704-13  0.356
2013 Richter SG, Elli D, Kim HK, Hendrickx AP, Sorg JA, Schneewind O, Missiakas D. Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria. Proceedings of the National Academy of Sciences of the United States of America. 110: 3531-6. PMID 23401520 DOI: 10.1073/Pnas.1217337110  0.567
2013 Allen CA, Babakhani F, Sears P, Nguyen L, Sorg JA. Both fidaxomicin and vancomycin inhibit outgrowth of Clostridium difficile spores. Antimicrobial Agents and Chemotherapy. 57: 664-7. PMID 23147724 DOI: 10.1128/Aac.01611-12  0.336
2011 Bouillaut L, McBride SM, Sorg JA. Genetic manipulation of Clostridium difficile. Current Protocols in Microbiology. Unit 9A.2. PMID 21400677 DOI: 10.1002/9780471729259.Mc09A02S20  0.632
2010 Sorg JA, Sonenshein AL. Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid Journal of Bacteriology. 192: 4983-4990. PMID 20675492 DOI: 10.1128/Jb.00610-10  0.649
2010 Giel JL, Sorg JA, Sonenshein AL, Zhu J. Metabolism of bile salts in mice influences spore germination in clostridium difficile Plos One. 5. PMID 20090901 DOI: 10.1371/Journal.Pone.0008740  0.602
2009 Sorg JA, Dineen SS. Laboratory maintenance of Clostridium difficile. Current Protocols in Microbiology. Unit9A.1. PMID 19235151 DOI: 10.1002/9780471729259.Mc09A01S12  0.457
2009 Sorg JA, Sonenshein AL. Chenodeoxycholate is an inhibitor of Clostridium difficile spore germination Journal of Bacteriology. 191: 1115-1117. PMID 19060152 DOI: 10.1128/Jb.01260-08  0.606
2008 Blaylock B, Sorg JA, Schneewind O. Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA. Molecular Microbiology. 70: 1210-22. PMID 18976277 DOI: 10.1111/J.1365-2958.2008.06474.X  0.55
2008 Riordan KE, Sorg JA, Beruhe BJ, Schneewind O. Impassable YscP substrates and their impact on the Yersinia enterocolitica type III secretion pathway Journal of Bacteriology. 190: 6204-6216. PMID 18641141 DOI: 10.1128/Jb.00467-08  0.762
2008 Sorg JA, Sonenshein AL. Bile salts and glycine as cogerminants for Clostridium difficile spores Journal of Bacteriology. 190: 2505-2512. PMID 18245298 DOI: 10.1128/Jb.01765-07  0.664
2006 Sorg JA, Blaylock B, Schneewind O. Secretion signal recognition by YscN, the Yersinia type III secretion ATPase Proceedings of the National Academy of Sciences of the United States of America. 103: 16490-16495. PMID 17050689 DOI: 10.1073/Pnas.0605974103  0.538
2005 Sorg JA, Miller NC, Marketon MM, Schneewind O. Rejection of impassable substrates by Yersinia type III secretion machines. Journal of Bacteriology. 187: 7090-102. PMID 16199580 DOI: 10.1128/Jb.187.20.7090-7102.2005  0.544
2005 Sorg JA, Miller NC, Schneewind O. Substrate recognition of type III secretion machines - Testing the RNA signal hypothesis Cellular Microbiology. 7: 1217-1225. PMID 16098210 DOI: 10.1111/J.1462-5822.2005.00563.X  0.56
2004 Goss JW, Sorg JA, Ramamurthi KS, Ton-That H, Schneewind O. The secretion signal of YopN, a regulatory protein of the Yersinia enterocolitica type III secretion pathway. Journal of Bacteriology. 186: 6320-4. PMID 15342604 DOI: 10.1128/Jb.186.18.6320-6324.2004  0.678
2004 Cambronne ED, Sorg JA, Schneewind O. Binding of SycH Chaperone to YscM1 and YscM2 Activates Effector yop Expression in Yersinia enterocolitica Journal of Bacteriology. 186: 829-841. PMID 14729710 DOI: 10.1128/Jb.186.3.829-841.2004  0.572
Show low-probability matches.