Lucy Liu - Related publications

2017- Harvard Medical School, Boston, MA, United States 
Neurodegeneration, Lipid metabolism, neuron glia communication, Drosophila, mice
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Standage SW, Xu S, Brown L, Ma Q, Koterba A, Lahni P, Devarajan P, Kennedy MA. NMR-Based Serum and Urine Metabolomic Profile Reveals Suppression of Mitochondrial Pathways in Experimental Sepsis-Associated Acute Kidney Injury. American Journal of Physiology. Renal Physiology. PMID 33843271 DOI: 10.1152/ajprenal.00582.2020   
2021 Chen M, Luo Y, Men L, Lin B, Lin H, Li Y, Zhong G, Zhong X, Fu W, Zhou H, Tong G, Liu Q, Luan J. Investigating the mechanisms of Modified Xiaoyaosan (tiaogan-liqi prescription) in suppressing the progression of atherosclerosis, by means of integrative pharmacology and experimental validation. Aging. 13. PMID 33839698 DOI: 10.18632/aging.202832   
2021 Park JH, Hayakawa K. Extracellular Mitochondria Signals in CNS Disorders. Frontiers in Cell and Developmental Biology. 9: 642853. PMID 33748135 DOI: 10.3389/fcell.2021.642853   
2021 Tardelli M, Bruschi FV, Fuchs CD, Claudel T, Auer N, Kunczer V, Ronda OAHO, Verkade HJ, Stojakovic T, Scharnagl H, Trauner M. Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice. International Journal of Molecular Sciences. 22. PMID 33672787 DOI: 10.3390/ijms22042126   
2021 Hewitson TD, Smith ER. A Metabolic Reprogramming of Glycolysis and Glutamine Metabolism Is a Requisite for Renal Fibrogenesis-Why and How? Frontiers in Physiology. 12: 645857. PMID 33815149 DOI: 10.3389/fphys.2021.645857   
2021 Zhou J, Singh BK, Ho JP, Lim A, Bruinstroop E, Ohba K, Sinha RA, Yen PM. mediator subunit is a key regulator of hepatic autophagy and lipid metabolism. Autophagy. 1-19. PMID 33734012 DOI: 10.1080/15548627.2021.1899691   
2021 Yang Z, Roth K, Agarwal M, Liu W, Petriello MC. The Transcription Factors CREBH, PPARa, and FOXO1 as Critical Hepatic Mediators of Diet-Induced Metabolic Dysregulation: Transcription factors and metabolic diseases. The Journal of Nutritional Biochemistry. 108633. PMID 33789150 DOI: 10.1016/j.jnutbio.2021.108633   
2021 Wu H, Xu X, Zheng A, Wang W, Mei L, Chen Y, Sun S, Jiang L, Wu Y, Zhou Y, Zheng M, Chen Q. TIPE1 Inhibits Hepatic Steatosis, Inflammation, and Fibrosis by Suppressing Polyubiquitination of ASK1. Hepatology (Baltimore, Md.). PMID 33713358 DOI: 10.1002/hep.31801   
2021 Ye J, Haskey N, Dadlani H, Zubaidi HM, Barnett JA, Ghosh S, Gibson DL. Deletion of mucin 2 induces colitis with concomitant metabolic abnormalities in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 33728986 DOI: 10.1152/ajpgi.00277.2020   
2021 Zhang Z, Liu S, Qi Y, Aluo Z, Zhang L, Yu L, Li Q, Luo Z, Sun Z, Zhou L, Li Y. Calcium supplementation relieves high-fat diet-induced liver steatosis by reducing energy metabolism and promoting lipolysis. The Journal of Nutritional Biochemistry. 108645. PMID 33838230 DOI: 10.1016/j.jnutbio.2021.108645   
2021 Xu F, Li Y, Cao Z, Zhang J, Huang W. AFB-induced mice liver injury involves mitochondrial dysfunction mediated by mitochondrial biogenesis inhibition. Ecotoxicology and Environmental Safety. 216: 112213. PMID 33838459 DOI: 10.1016/j.ecoenv.2021.112213   
2021 Mesquita RD, Gaviraghi A, Gonçalves RLS, Vannier-Santos MA, Mignaco JA, Fontes CFL, Machado LESF, Oliveira MF. Cytochrome Oxidase at Full Thrust: Regulation and Biological Consequences to Flying Insects. Cells. 10. PMID 33671793 DOI: 10.3390/cells10020470   
2021 Choi MJ, Jung SB, Chang JY, Shong M. Cellular and Intercellular Homeostasis in Adipose Tissue with Mitochondria-Specific Stress. Endocrinology and Metabolism (Seoul, Korea). 36: 1-11. PMID 33677920 DOI: 10.3803/EnM.2021.956   
2021 Lai KKY, Hu X, Chosa K, Nguyen C, Lin DP, Lai KK, Kato N, Higuchi Y, Highlander SK, Melendez E, Eriguchi Y, Fueger PT, Ouellette AJ, Chimge NO, Ono M, et al. p300 Serine 89: A Critical Signaling Integrator and Its Effects on Intestinal Homeostasis and Repair. Cancers. 13. PMID 33799418 DOI: 10.3390/cancers13061288   
2021 Han X, Zhao S, Song H, Xu T, Fang Q, Hu G, Sun L. Kaempferol alleviates LD-mitochondrial damage by promoting autophagy: Implications in Parkinson's disease. Redox Biology. 41: 101911. PMID 33713908 DOI: 10.1016/j.redox.2021.101911   
2021 Yang X, Ding W, Qian X, Jiang P, Chen Q, Zhang X, Lu Y, Wu J, Sun F, Pan Z, Li X, Pan W. Infection Leads to the Reprogramming of Glucose and Lipid Metabolism in the Colon of Mice. Frontiers in Veterinary Science. 8: 645807. PMID 33791356 DOI: 10.3389/fvets.2021.645807   
2021 Kang SG, Choi MJ, Jung SB, Chung HK, Chang JY, Kim JT, Kang YE, Lee JH, Hong HJ, Jun SM, Ro HJ, Suh JM, Kim H, Auwerx J, Yi HS, et al. Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response. Iscience. 24: 102181. PMID 33718833 DOI: 10.1016/j.isci.2021.102181   
2021 Hung TC, Zhao N, Huang C, Liu S, Liu T, Huang W, Xu X, Ji ZL, Yang S. Exploring the mechanism of PingTang No.5 capsule on nonalcoholic fatty liver disease through network pharmacology and experimental validation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 138: 111408. PMID 33684693 DOI: 10.1016/j.biopha.2021.111408   
2021 Xiong S, Ma M, Xu Y, Wei F, Gu Q, He X, Xu X. Protective effects of peptide FK18 against neuro-excitotoxicity in SH-SY5Y cells. Experimental and Therapeutic Medicine. 21: 451. PMID 33747186 DOI: 10.3892/etm.2021.9880   
2021 Ye L, Zhang X, Zhou Q, Tan B, Xu H, Yi Q, Yan L, Xie M, Zhang Y, Tian J, Zhu J. Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Frontiers in Cell and Developmental Biology. 9: 644667. PMID 33768096 DOI: 10.3389/fcell.2021.644667   
2021 Wang X, Shen X, Yan Y, Li H. Pyruvate dehydrogenase kinases (PDKs):An Overview towards Clinical Applications. Bioscience Reports. PMID 33739396 DOI: 10.1042/BSR20204402   
2021 Zhou Y, Guo Y, Zhu Y, Sun Y, Li W, Li Z, Wei L. Dual PPARγ/ɑ Agonist Oroxyloside Suppresses Cell Cycle Progression by Glycolipid Metabolism Switch-Mediated Increase of Reactive Oxygen Species Levels. Free Radical Biology & Medicine. PMID 33713839 DOI: 10.1016/j.freeradbiomed.2021.02.032   
2021 Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y. Deficiency of mitochondrial glycerol 3-phosphate dehydrogenase exacerbates podocyte injury and the progression of diabetic kidney disease. Diabetes. PMID 33741719 DOI: 10.2337/db20-1157   
2021 Huang K, Liu C, Peng M, Su Q, Liu R, Guo Z, Chen S, Li Z, Chang G. Glycoursodeoxycholic Acid Ameliorates Atherosclerosis and Alters Gut Microbiota in Apolipoprotein E-Deficient Mice. Journal of the American Heart Association. e019820. PMID 33787322 DOI: 10.1161/JAHA.120.019820   
2021 Xiang L, Shao Y, Chen Y. Mitochondrial Dysfunction and Mitochondrion-targeted Therapeutics in Liver Diseases. Journal of Drug Targeting. 1-41. PMID 33788656 DOI: 10.1080/1061186X.2021.1909051   
2021 Bekhite M, González-Delgado A, Hübner S, Haxhikadrija P, Kretzschmar T, Müller T, Wu JMF, Bekfani T, Franz M, Wartenberg M, Gräler M, Greber B, Schulzedrp PC. The role of ceramide accumulation in human induced pluripotent stem cell-derived cardiomyocytes on mitochondrial oxidative stress and mitophagy. Free Radical Biology & Medicine. PMID 33705961 DOI: 10.1016/j.freeradbiomed.2021.02.016   
2021 van Leent MMT, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, Pérez-Medina C, et al. Prosaposin mediates inflammation in atherosclerosis. Science Translational Medicine. 13. PMID 33692130 DOI: 10.1126/scitranslmed.abe1433   
2021 Doroshenko ER, Drohomyrecky PC, Gower A, Whetstone H, Cahill LS, Ganguly M, Spring S, Yi TJ, Sled JG, Dunn SE. Peroxisome Proliferator-Activated Receptor-δ Deficiency in Microglia Results in Exacerbated Axonal Injury and Tissue Loss in Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 12: 570425. PMID 33732230 DOI: 10.3389/fimmu.2021.570425   
2021 Huang Y, Zhao C, Kong Y, Tan P, Liu S, Liu Y, Zeng F, Yuan Y, Zhao B, Wang J. Elucidation of the mechanism of NEFA-induced PERK-eIF2α signaling pathway regulation of lipid metabolism in bovine hepatocytes. The Journal of Steroid Biochemistry and Molecular Biology. 105893. PMID 33819629 DOI: 10.1016/j.jsbmb.2021.105893   
2021 Pajed L, Taschler U, Tilp A, Hofer P, Kotzbeck P, Kolleritsch S, Radner FPW, Pototschnig I, Wagner C, Schratter M, Eder S, Huetter S, Schreiber R, Haemmerle G, Eichmann TO, et al. Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase. Communications Biology. 4: 323. PMID 33692445 DOI: 10.1038/s42003-021-01858-z   
2021 Gu Y, Zhang Y, Li M, Huang Z, Jiang J, Chen Y, Chen J, Jia Y, Zhang L, Zhou F. Ferulic Acid Ameliorates Atherosclerotic Injury by Modulating Gut Microbiota and Lipid Metabolism. Frontiers in Pharmacology. 12: 621339. PMID 33841148 DOI: 10.3389/fphar.2021.621339   
2021 Liu X, Yuan Q, Li GX, Jia CC, Liu JY, Yang YQ, Wang XY, Hou Y, Wang B. Regulation of Superoxide by BAP31 through Its Effect on p22 and Keap1/Nrf2/HO-1 Signaling Pathway in Microglia. Oxidative Medicine and Cellular Longevity. 2021: 1457089. PMID 33777312 DOI: 10.1155/2021/1457089   
2021 Vandenberg GG, Dawson NJ, Head A, Scott GR, Scott AL. Astrocyte-mediated disruption of ROS homeostasis in Fragile X mouse model. Neurochemistry International. 105036. PMID 33785420 DOI: 10.1016/j.neuint.2021.105036   
2021 Miao Y, Qin H, Zhong Y, Huang K, Rao C. Novel adipokine asprosin modulates browning and adipogenesis in white adipose tissue. The Journal of Endocrinology. PMID 33705351 DOI: 10.1530/JOE-20-0503   
2021 Hsiao YH, Wang YH, Lin WS, Cheng YC, Nagabhushanam K, Ho CT, Pan MH. Molecular Mechanisms of the Anti-obesity Properties of in Mice Fed a High-Fat Diet. Journal of Agricultural and Food Chemistry. PMID 33848157 DOI: 10.1021/acs.jafc.1c01117   
2021 Liu PY, Chen CC, Chin CY, Liu TJ, Tsai WC, Chou JL, Huang CY, Chen YG, Chen YC. E3 ubiquitin ligase Grail promotes hepatic steatosis through Sirt1 inhibition. Cell Death & Disease. 12: 323. PMID 33771967 DOI: 10.1038/s41419-021-03608-9   
2021 Cho BO, Kim JH, Che DN, Kang HJ, Shin JY, Hao S, Park JH, Wang F, Lee YJ, Jang SI. Kushenol C Prevents Tert-Butyl Hydroperoxide and Acetaminophen-Induced Liver Injury. Molecules (Basel, Switzerland). 26. PMID 33804228 DOI: 10.3390/molecules26061635   
2021 Zeng M, Xu J, Zhang Z, Zou X, Wang X, Cao K, Lv W, Cui Y, Long J, Feng Z, Liu J. Htd2 deficiency-associated suppression of α-lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes. Redox Biology. 41: 101948. PMID 33774475 DOI: 10.1016/j.redox.2021.101948   
2021 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT. Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21450. PMID 33788980 DOI: 10.1096/fj.202002740R   
2021 Verschoor PJ, Greig FH, Rochford JJ, Levate G, Delibegovic M, Thompson D, Leeson-Payne A, Dekeryte R, Banks R, Ramos JW, Nixon GF. Phosphoprotein enriched in astrocytes (PEA)-15 is a novel regulator of adipose tissue expansion. Scientific Reports. 11: 6949. PMID 33772049 DOI: 10.1038/s41598-021-86250-x   
2021 Omarjee O, Mathieu AL, Quiniou G, Moreews M, Ainouze M, Frachette C, Melki I, Dumaine C, Gerfaud-Valentin M, Duquesne A, Kallinich T, Tahir Turanli E, Malcus C, Viel S, Pescarmona R, et al. LACC1 deficiency links juvenile arthritis with autophagy and metabolism in macrophages. The Journal of Experimental Medicine. 218. PMID 33606008 DOI: 10.1084/jem.20201006   
2021 Zhang Q, Song W, Zhao B, Xie J, Sun Q, Shi X, Yan B, Tian G, Liang X. Quercetin Attenuates Diabetic Peripheral Neuropathy by Correcting Mitochondrial Abnormality via Activation of AMPK/PGC-1α Pathway and . Frontiers in Neuroscience. 15: 636172. PMID 33746703 DOI: 10.3389/fnins.2021.636172   
2021 Zhang X, Ye L, Xu H, Zhou Q, Tan B, Yi Q, Yan L, Xie M, Zhang Y, Tian J, Zhu J. NRF2 is required for structural and metabolic maturation of human induced pluripotent stem cell-derived ardiomyocytes. Stem Cell Research & Therapy. 12: 208. PMID 33762018 DOI: 10.1186/s13287-021-02264-2   
2021 Huang CF, Liu SH, Su CC, Fang KM, Yen CC, Yang CY, Tang FC, Liu JM, Wu CC, Lee KI, Chen YW. Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite of bisphenol A. Toxicology. 152764. PMID 33771661 DOI: 10.1016/j.tox.2021.152764   
2021 Sun M, Gu Y, Glisan SL, Lambert JD. Dietary Cocoa Ameliorates Non-Alcoholic Fatty Liver Disease and Increases Markers of Antioxidant Response and Mitochondrial Biogenesis in High Fat-Fed Mice. The Journal of Nutritional Biochemistry. 108618. PMID 33711421 DOI: 10.1016/j.jnutbio.2021.108618   
2021 Huang HC, Chen CJ, Lai YH, Lin YC, Chiou WC, Lu HF, Chen YF, Chen YH, Huang C. Aril Ameliorates Diet-Induced Metabolic Dysfunction and Non-Alcoholic Fatty Liver by Modulating Gut Microbiota. International Journal of Molecular Sciences. 22. PMID 33808007 DOI: 10.3390/ijms22052640   
2021 Kim YN, Shin JH, Kyeong DS, Cho SY, Kim MY, Lim HJ, Jimenez MRR, Kim IY, Lee MO, Bae YS, Seong JK. Ahnak deficiency attenuates high-fat diet-induced fatty liver in mice through FGF21 induction. Experimental & Molecular Medicine. PMID 33785868 DOI: 10.1038/s12276-021-00573-3   
2021 Ham J, Lim W, Song G. Flufenoxuron suppresses the proliferation of testicular cells by targeting mitochondria in mice. Pesticide Biochemistry and Physiology. 173: 104773. PMID 33771252 DOI: 10.1016/j.pestbp.2021.104773   
2021 Jeon HJ, Choi DK, Choi J, Lee S, Lee H, Yu JH, Min SH. D-Mannitol Induces a Brown Fat-like Phenotype via a β3-Adrenergic Receptor-Dependent Mechanism. Cells. 10. PMID 33807329 DOI: 10.3390/cells10040768   
2021 Decano JL, Singh SA, Bueno CG, Lee LH, Halu A, Chelvanambi S, Matamalas JT, Zhang H, Mlynarchik AK, Qiao J, Sharma A, Mukai S, Wang J, Anderson DG, Ozaki CK, et al. Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development. Circulation. PMID 33821665 DOI: 10.1161/CIRCULATIONAHA.119.043724